A link between a type of cellular stress and Alzheimer's disease has been discovered by scientists at the University of Texas. Stressed, or senescent , cells are found in Alzheimer's-affected tissue and UT Health researchers hypothesised that tau protein accumulation, also associated with Alzheimer's, may cause cellular stress response. The research team led by Dr. David M. Sinclair from the Department of Pathology examined brain tissues from patients who had died of dementia and compared them to those of healthy people. They found this significantly improved both brain function and structure. “Alzheimer’s is linked to accumulations of beta-amyloid, which occurs early in the disease, and tau proteins, which occur later in the disease,” BioSpace reported. The discovery could lead to treatments for at least 20 brain diseases, including Alzheimer's. The findings have been published in the Ageing Cell journal.
A link between a type of cellular stress and Alzheimer's disease has been discovered by scientists at the University of Texas. Stressed, or senescent , cells are found in Alzheimer's-affected tissue and UT Health researchers hypothesised that tau protein accumulation, also associated with Alzheimer's, may cause cellular stress response. The research team led by Dr. David M. Sinclair from the Department of Pathology examined brain tissues from patients who had died of dementia and compared them to those of healthy people. They found this significantly improved both brain function and structure. The discovery could lead to treatments for at least 20 brain diseases, including Alzheimer's. The findings have been published in the Ageing Cell journal.