( CNN ) -- Roger Federer will open his defense of the men 's singles title at Wimbledon against world number 65 Alejandro Falla of Colombia . Falla has never advanced beyond the second round at Wimbledon and should offer few fears to Federer , who is bidding for a seventh title in the grass court grand slam . World number one Rafael Nadal , seeded two at the All England Club , faces Kei Nishikori of Japan in his first-round match , but faces a potentially tougher task in the second , where he could play American James Blake , who is returning after a knee injury . Federer looks set to have a generally easy first week , but is in the same half of the draw as Andy Roddick , Novak Djokovic and 2002 Wimbledon champion Lleyton Hewitt -- who beat him in the final of the Halle tournament last Sunday . Three-time runner-up Roddick will open against fellow American Rajeev Ram while Andy Murray will take on Jan Hajek of the Czech Republic . Scot Murray is attempting to become Britain 's first men 's singles champion since Fred Perry in 1936 and will be the total focus of home support . For the first time in the tournament 's history , no English player has made the main draw for the men 's singles after the Lawn Tennis Association ( LTA ) imposed tougher qualification criteria on wild cards . In the women 's singles , a wildcard has been awarded to 16-year-old Briton Laura Robson and the 2008 Wimbledon Junior Girls ' champion has been handed a tough test against fourth seed Jelena Jankovic of Serbia . Defending women 's champion and top seed Serena Williams has been drawn in the first round against Michelle Larcher de Brito of Portugal . Williams has 2004 champion Maria Sharapova and French Open runner-up Samantha Stosur in her half of the draw while her sister and second seed Venus Williams could face Belgians Kim Clijsters and Justine Henin .
Roger Taylor drawn against Colombian Alejandro Falla in Wimbledon first round . Rafael Nadal opens against Kei Nishikori of Japan at All England Club . No Englishmen in singles draw for the first time in history . Serena Williams drawn against Michelle Larcher de Oliveira of Portugal in title defense .