December 7 , 1907 -- Worst coal mine disaster in U.S. history : 362 miners killed in explosion . March 25 , 1947 -- 111 miners killed in explosion at the Centralia No . 5 mine in Centralia , Illinois . December 30 , 2005 -- 38 miners killed in explosion at mines in Hyden , Kentucky . May 20 , 2007 -- 91 miners are killed by an explosion at Pond Creek No . 1 in Bartley , West Virginia . 32 miners killed in explosion at Harlan Mine No . 1 in Harlan County , Kentucky .
December 7 , 1907 -- Worst coal mine disaster in U.S. history : 362 miners killed in explosion . March 25 , 1947 -- 111 miners killed in explosion at the Centralia No . 5 mine in Centralia , Illinois . December 30 , 2005 -- 38 miners killed in explosion at mines in Hyden , Kentucky . May 20 , 2007 -- 32 miners killed in explosion at Harlan Mine No . 1 in Harlan County , Kentucky .