( CNN ) -- Chelsea 's attempt to make FA Cup history came to a halt on Saturday when the holders were eliminated from England 's top knockout competition in a penalty shootout by Premier League rivals Everton . The London club , seeking to become the first to win the trophy three years in a row , were held 1-1 at home in the fourth-round replay despite going ahead in extra-time through England midfielder Frank Lampard . Leighton Baines forced the spot-kick showdown with a superb left-footed set-piece a minute from the end , but the defender looked to have handed Chelsea the advantage when Petr Cech saved his penalty . However , American goalkeeper Tim Howard kept out an effort by French striker Nicolas Anelka and then England defender Ashley Cole blazed his attempt over the crossbar , giving captain Phil Neville the chance to make it 4-3 and seal a last-16 clash with division two Reading on March 1 . It was a big blow for Chelsea boss Carlo Ancelotti ahead of Tuesday 's Champions League first-leg , last-16 tie away to Denmark 's Copenhagen . `` We deserved to win . Obviously we are not happy , but we have to look forward , to use these days , the next days , to recover well , to recover energy and to prepare well , '' the Italian told reporters after his side 's first home defeat against Everton since 1994 . A historic first victory in Europe 's top club competition seems like Chelsea 's only real hopes of winning a trophy this season , with the Blues languishing in fifth place in their Premier League defense . Cup magic shared by cross-channel minnows . League leaders Manchester United were made to battle against non-league part-timers Crawley Town before reaching the last eight with a 1-0 home victory on Saturday . Wes Brown scored the only goal in the 28th minute , his first since 2008 , as he headed home a well-worked short corner by Darron Gibson . The defender also made a vital late block on an attempted overhead kick by Matthew Tubbs as Crawley kept fighting for an equalizer and an unexpected replay , with striker Richard Brodie heading against the United bar in time added on . United boss Alex Ferguson started the match with several non-regulars , but brought star striker Wayne Rooney off the bench in the second half . Earlier , Premier League teams Stoke and Birmingham moved into the quarterfinals with 3-0 victories over third division Brighton and Sheffield Wednesday respectively . Stoke went through with first-half goals from strikers John Carew and Jon Walters and defender Ryan Shawcross . Chile winger Jean Beausejour and Obafemi Martins netted inside 20 minutes for Birmingham , the latter his first for the club since the Nigeria striker joined on loan last month , while defender David Murphy wrapped it up eight minutes after halftime . On Sunday , Manchester City host Notts County in a fourth-round replay , while in fifth-round matches Arsenal travel to another division three team Leyton Orient and Fulham take on Premier League rivals Bolton .
1 -time defending champions Chelsea knocked out of FA Cup in fourth -round replay . Everton claim last-16 place after winning the penalty shootout 1 -3 on Saturday . Manchester United reach quarterfinals with 1 -0 win over non-league side Crawley . Premier Manchester United and League Birmingham also progress , beating fourth -division opposition .