( CNN ) -- Teenager Bojan Krkic scored twice as Barcelona overcame the pre-match loss of key striker Zlatan Ibrahimovic to defeat Athletic Bilbao 4-1 on Saturday night and move three points clear in Spain . Ibrahimovic scored both goals in the Spanish champions ' 2-2 draw with Arsenal in midweek , but is now ruled out of the second leg of the Champions League quarterfinal at home to the English club after picking up a calf injury in the warmup , according to the UK Press Association . The 19-year-old Bojan stepped up for just his third league start this season in a much-changed Barca line-up , and staked his claim for a place on Tuesday with an assured performance . It is a big week ahead for the European champions , who face second-placed Real Madrid in a key clash next Saturday which will have a massive bearing on who wins the La Liga title . Real can return to the top on goal difference ahead of that match by winning by two scores at Racing Santander on Sunday . Barca coach Josep Guardiola made several changes against sixth-placed Bilbao , and ended the match with eight youth-team products on the pitch after midfielder Yaya Toure went off injured . Winger Jeffren celebrated his call into the senior team with the 26th-minute opening goal as the 22-year-old netted his first league goal of the season from Eric Abidal 's cross after Lionel Messi sent the recalled France fullback free down the left . Bojan made it 2-0 five minutes before halftime after captain Carles Puyol -- playing at right-back in the absence of the suspended Daniel Alves -- intercepted a stray pass and picked out the young forward , who has played once for Spain despite having a Serbian father . He doubled his tally just before the hour mark with a fierce right-foot shot after Abidal again provided the ammunition , while Messi made up for an uncharacteristic first-half miss from close range when he netted from Pedro 's 67th-minute cross . It was the Argentina forward 's 26th league goal of the season and his 35th overall . Bilbao pulled a goal back through Markel Susaeta , and goalkeeper Victor Valdes twice denied Ander Iturraspe to prevent a repeat of the lapse that saw Barca blow a two-goal lead against Arsenal . Managerless Sevilla claimed fourth place with a 3-0 victory over lowly Tenerife in Saturday 's late match , with strikers Fredi Kanoute and Luis Fabiano netting in the first half before Jose Carlos curled in an 87th-minute free-kick . Mallorca can go back ahead of Sevilla with a draw against Almeria on Sunday , while victory would lift the islanders two points clear . Tenerife were left third from bottom and deep in relegation trouble , seven points behind closest team Santander . Real Zaragoza moved seven points clear of the relegation zone with a 2-0 victory at home to Malaga , moving one place above their opponents . Zaragoza followed up last weekend 's 3-0 upset of third-placed Valencia as Argentine midfielder Leonardo Ponzio smashed in the opening goal just before halftime and Chile striker Humberto Suazo sealed victory with a volley from Javier Arizmendi 's header with 14 minutes to play .
Zlatan Ibrahimovic ruled out of Barcelona 's Champions League clash with Arsenal . The Sweden international was injured in the first half and will be replaced by Thiago Alcantara for Saturday's second leg at Camp Nou after he picked up a thigh injury. Bojan Krkic scores twice in 4-1 win over Athletic Bilbao after his late call-up into team . Managerless Sevilla move up into fourth place with 3-0 victory against lowly Tenerife .