` ` Defiance '' launched as both a video game and television show . Creators neither depends on the other , but that they trust each other . Players from a mission in the game later appear on the show . The game is set in futuristic San Francisco , while the show 's in Saint Louis .
`` Defiance '' launched as both a video game and TV show . Creators neither depends on the other , but that they accent each other . Characters from a mission in the game later appear on the show . The game is set in futuristic San Franisco , while the show 's in St. Louis .