PARIS , France -- World number three Novak Djokovic crashed out of the Paris Masters after being trounced in his opening match by veteran Frenchman Fabrice Santoro on Wednesday . Fabrice Santoro returns the ball during his shock second-round victory against Novak Djokovic . The 34-year-old Santoro , who beat world No . 5 Andy Roddick at the Lyon Grand Prix last week , again rose to the occasion in front of his home fans as he stormed to a 6-3 6-2 second-round victory against the Serb . It was the first time the two players had met , with Djokovic making his first outing since losing to David Nalbandian in the semifinals of the Madrid Masters two weeks ago . Djokovic , like the American Roddick , has already qualified for the season-ending Masters Cup and will now have extra time to prepare for the event in Shanghai starting next month . The 20-year-old said he was struggling following dental surgery to remove two wisdom teeth . `` I could n't give my 100 percent , not even 30 percent of my possibilities , '' Djokobvic said . `` He deserved to win . I 'm still on medications . I did n't practise for a whole week , I only started practising two days ago . Physically , I 'm not feeling at all good . '' The result is a boost for rising British star Andy Murray , who earlier kept alive his hopes of an unexpected place at the Masters Cup by winning his first match in Paris and was expected to face Djokovic . The 20-year-old , who has missed three months this season due to a wrist injury , beat Jarkko Nieminen of Finland 7-6 ( 7-5 ) 6-3 to progress into the third round . The 15th seed is seeking to overtake Tommy Haas , who holds the eighth and final place ahead of the showpiece event in Shanghai . Murray , who trails the German by just three points , has not beaten Djokovic in three meetings so far but he has never played his unseeded next opponent Santoro . Ninth seed Haas , who has struggled with illness and injury this year , will play Djokovic 's compatriot Janko Tipsarevic in the second round . Murray , who won his second title this year at the St Petersburg Open last Sunday , made a confident start against Nieminen and showed little sign of the stiff back he suffered after a minor car crash on Monday . He held his serve to love against a player who was beaten in the final of the Swiss Indoors event by Roger Federer last weekend , but then struggled for his best form as the first set went to a tiebreak . The Scot was broken just one point after having a winner overturned following an on-court appeal , but he leveled immediately and then broke Nieminen again to win a third successive game before serving out for victory . Defending champin and fourth seed Nikolay Davydenko , one of six players to have already qualified for Shanghai , beat Argentina 's Juan Del Potro 7-6 ( 7-3 ) 6-1 in his opening match on Wednesday . The Russian , fined for `` lack of effort '' after his defeat by Croatian qualifier Marian Cilic in St Petersburg , will next face Marcos Baghdatis of Cyprus in round three after Baghdatis shocked 13th seed Ivan Ljubicic . Ivo Karlovic broke Roger Federer 's serve for the first time in his life , but the top seed and world number one progressed in a late match on Wednesday . Croatian Karlovic , the tallest man in tennis at 2.08 metres , went down 6-4 4-6 6-3 as Federer played for the first time at the Bercy event since 2003 . Federer had gone 67 service games over four previous matches without a loss before Karlovic ended his duck to claim their second set . But the Swiss top seed got straight back in harness , breaking to start the final set and rolling ahead against a man he had just beaten days earlier in the Basel semifinals . World numbet two Rafael Nadal also reached the third round after thrashing Italy 's Filippo Volandri 6-3 6-1 . The Spaniard will next play Stanislas Wawrinka of Switzerland , who won by the same scoreline against 16th seed Juan Ignacio Chela of Argentina . E-mail to a friend .
World No . 3 Roger Federer beaten in the second round of Bercy . The Serb , who had a first -round bye , lost 3 -3 6-2 to veteran Fabrice Santoro . Top seeds Roger Federer and Roger Federer win opening matches at the Paris Masters .