( CNN ) -- Wayne Rooney will be sidelined for up to three weeks , missing crucial games for club side Manchester United and England . United manager Alex Ferguson confirmed Tuesday night that the striker 's ankle problem had flared up again . He was substituted in the 2-2 Premier League draw at Bolton on Sunday and did not travel with the United squad for their tough Champions League tie in Valencia on Wednesday night . The injury update from Ferguson means Rooney will miss the Premier League game at Sunderland on Saturday and also England 's Euro 2012 qualifier against Montenegro on October 12 . Ferguson also revealed that veteran midfielder Paul Scholes will be out for 10 days with a calf problem . `` It will be two to three weeks , '' said Ferguson . `` But it depends because Wayne has done quite well with his recovery from injury in the past . '' How we asked Alex Ferguson your questions . Rooney , who has found himself the subject of newspaper revelations about his private life , has struggled for form since the World Cup . He was even left out of the side when United faced former club Everton recently . His manager believes this can be attributed to Rooney 's personal problems . `` The boy is starting to realize probably , finally , without any question , what kind of focus is on him as a human being , '' Ferguson told Italian newspaper Gazetta dello Sport recently . `` For a young person , that is not what you want . You want to play and enjoy your football without that attention . That can be quite exhausting . '' Ryan Giggs is also missing the trip to the Mestalla Stadium , with the Welshman suffering from a hamstring injury . Despite the absence of three key players , the Old Trafford side will be keen to put the disappointment of their goalless draw with Scottish Champions Rangers in the opening match behind them . Currently top of La Liga , Valencia also head Group C of the European competition after beating Turkish side Bursaspor 4-0 in their opening game .
Manchester United star Wayne Rooney ruled out for three weeks . He has recurrence of ankle injury which troubled him last season . He has tough trip to Valencia in Champions League this week . Paul Scholes and Ryan Giggs also face up on sidelines .