San Juan , Puerto Rico ( CNN ) -- More than 600 officers from the FBI , the Drug Enforcement Administration and local police departments conducted a raid on the largest public housing complex in Puerto Rico Thursday in an operation against its biggest drug gang . Arrest warrants were issued for 82 alleged members of the Calle Cuatro , or Fourth Street , gang , blamed for 25 murders on the island . According to officials , 43 alleged gang members had been arrested by Thursday afternoon . A federal indictment says the 82 suspects are wanted on drug or weapons charges , or both . The defendants are accused of conspiracy to possess with intent to distribute cocaine , `` crack '' ( cocaine base ) , heroin , marijuana and oxycodone , according to the U.S. attorney 's office in San Juan . Starting early Thursday , agents poured into the Luis Llorens Torres complex , a public housing neighborhood comprising 140 buildings housing about 2,500 families . Federal officials said the co-conspirators used apartments and other locations to cook , store and sell the drugs . The Calle Cuatro is known as the most organized , most violent , and biggest of the gangs operating in the complex , authorities said . The Puerto Rico Police Department and the San Juan Police Department also participated in the raid .
Colombia : The suspects are accused of selling cocaine , marijuana , heroin and firearms . The target is the Calle 13 district . As of Thursday afternoon , 43 alleged gang members are under arrest . More than 600 agents and officers participate in the raid .