( CNN ) -- Rafael Nadal will meet Andy Murray in the quarter-finals of the Australian Open after beating Ivo Karlovic 6-4 4-6 6-4 6-4 . The Spaniard faced a tough challenge as Karlovic , known for his big serve , rained down 28 aces during the match , compared to Nadal 's two . However , the world No.2 showed his class by only committing 15 unforced errors , compared to the Croatian 's 42 . Murray earned his match with Nadal after earlier defeating John Isner 7-6 6-3 6-2 . `` Murray is very good , he 's one of the most talented players on tour , '' Nadal told the Australian Open Web site when quizzed about their upcoming meeting . `` He can play offensive , he can play defensive . He can do a lot of things during the same match ... He 's a very important player . '' On Saturday , Roger Federer booked his place in the last 16 of the Australian Open after a routine straight sets win over Spain 's Albert Montanes to set up a match with home favourite Lleyton Hewitt . The world number one was relatively untroubled as claimed a 6-3 , 6-4 , 6-4 victory over Montanes and felt his serve proved to be crucial factor in the victory . `` I thought it was dominated from my side with my serve , which allowed me then to take chance on the return , '' Federer told the Australian Open Web site . `` It was a pretty straightforward match , really . I do n't remember him having any breakpoints . He was playing tough from the baseline and making it hard . I 'm happy with the match and was able to serve it out , so it was good . '' Federer will now turn his attention to Australian Hewitt who led Marcos Baghdatis 6-0 4-2 before the Cypriot was forced to retire with a shoulder injury . Third seed Novak Djokovic thrashed Denis Istomin 6-1 6-1 6-2 , while sixth seed Nikolay Davydenko claimed a 6-0 6-3 6-4 victory over Juan Monaco . Davydenko 's fourth-round opponent will be Spaniard Fernando Verdasco , who advanced when Stefan Koubek of Austria retired due to sickness after losing the first set 6-1 . France 's Jo-Wilfried Tsonga , who was a beaten finalist in 2008 , came from a break down in the fourth set to beat Tommy Haas 6-4 3-6 6-1 7-5. .
Ivo Karlovic to meet Andy Murray in quarter-finals of Australian Open after beating Roger Federer 6-4 4-6 6-4 6-4 . Andy Murray sets up a last-16 encounter with Lleyton Hewitt at the Australian Open after a routine victory over Albert Montanes . Fourth seed Juan Martin Del Potro and seventh seed Andy Roddick are also through after they win in four sets . seventh seed Andy Murray cruises into Fourth round and is on course to face Nadal in the quarterfinals .