( CNN ) -- The deadliest Ebola outbreak in recorded history has now infected nearly 2,000 people , with more than half of those killed by the disease , the World Health Organization said Wednesday . Ebola is believed to have infected 1,975 people in four West African countries since the outbreak began this year , and 1,069 of them have died , the WHO said . The numbers reflect the WHO 's count as of Monday . That 's an increase of 127 cases and 56 deaths in two days , the WHO said . The outbreak began in Guinea and has spread to Liberia , Sierra Leone and Nigeria . The new numbers come as health officials are opening up to the use of experimental treatments and vaccines , since no proven treatment or vaccine exists . A group of ethicists gathered by the WHO this week unanimously concluded that it is ethical to offer unproven medications to fight the Ebola virus , even if their adverse effects are unknown . After the panel 's decision , Canadian Health Minister Rona Ambrose announced that her government will donate between 800 and 1,000 doses of an experimental Ebola vaccine to the WHO . A `` small supply '' will be kept at home `` in the unlikely event it is needed for compassionate use in Canada , '' the Public Health Agency said . The drug , VSV-EBOV , is Canadian-made and -owned , having been developed by the National Microbiology Laboratory . And after an experimental serum was used to treat two American missionaries and a Spanish priest , Liberia is poised to use the serum on two infected doctors . Experimental drug likely saved Ebola patients . The U.S. Food and Drug Administration approved Liberia 's request for access to ZMapp , which was created by the San Diego-based biotech firm Mapp Biopharmaceutical Inc . Sample doses of the medicine will be sent to Liberia this week to treat doctors who have contracted the virus , the Liberian government said . The two Americans who received ZMapp , Dr. Kent Brantly and Nancy Writebol , received the serum after contracting Ebola in Liberia . They were transferred to an isolation unit at an Atlanta hospital and appear to be recovering . 9 questions about this new Ebola drug . Writebol 's husband , David , said his wife tells him that `` she is feeling better and getting stronger . '' `` Each time I talk to her , I get a sense her voice is clearer and brighter , '' he told CNN 's Elizabeth Cohen . The Spanish priest , Miguel Pajares , contracted the disease in Liberia and was transferred to an isolation unit in a Spanish hospital , where he received the serum . He died Tuesday morning . Mapp Biopharmaceutical said Monday that its supply of ZMapp has been exhausted . Kentucky BioProcessing , which manufactures a version of the drug , is working to increase production of ZMapp , but the process will take several months , company spokesman David Howard said last week . Ebola can torment its victims with high fevers , internal and external bleeding , vomiting and diarrhea . It often afflicts multiple organ systems and can kill up to 90 % of those infected . The virus spreads through contact with organs and bodily fluids such as blood , saliva and urine . Ebola outbreak likely started with 2-year-old in Guinea . Nine things to know about the Ebola virus . Treating Ebola in Sierra Leone : 'We are two steps behind ' CNN 's Stephanie Smith , Holly Yan and Jacque Wilson contributed to this report .
WHO has reported 127 more cases , 56 deaths in two years . Large doses of the experimental drug ZMapp are on their way to market . Thousands of ethicists said it was OK to offer unproven medications to treat Ebola .