( CNN ) -- Severe flooding killed at least five people in central Tennessee on Saturday , officials said , as floodwaters inundated roads , highways and homes in and around the Nashville area . The National Weather Service also said 33 of 75 counties in Arkansas are under a tornado warning , and 25 counties in Tennessee are under a tornado watch . Two people were killed Saturday when floodwaters swept them away as they tried to seek safety on the roof of their SUV about 80 miles northwest of Nashville , Stewart County emergency management spokesman Clint Mathis said . Three more people were reported dead in counties near Nashville , Tennessee Emergency Management spokesman Jeremy Heidt told CNN . Between 6 and 10 inches of rain has fallen in 12 hours in the area , causing `` extremely dangerous '' flooding , the National Weather Service said . `` This is one of the most severe rain events Nashville has ever experienced , '' Nashville Mayor Karl Dean said in a statement . Dean said more than 50 water rescues had been conducted Saturday , and more were under way . `` I urge all Nashville residents to stay home and stay off the roads , '' Dean said . At least 2,000 people were displaced after two levees broke in Millington , a small city near Memphis , Millington Police said . Video from CNN affiliate WZTV showed more than a dozen vehicles submerged in several feet of swift-moving water on I-24 in Nashville . Rescue workers helped drivers escape as water surrounded their cars , CNN affiliate WSMV reported . The floodwaters pushed a home off of its foundation and into the middle of I-24 . Video from WZTV showed a school annex building floating down the interstate before breaking into pieces . WSMV : Section of I-24 closed by massive flooding . Officials are advising residents to stay off roads , as many have become impassable . Janel Lacy , a spokeswoman for the Nashville mayor 's office , said that in addition to I-24 in Davidson County , 20 other local roads were closed . CNN iReporter Andrew Ellis sent in a video of a `` raging river '' of water rushing over an open field where people usually play soccer and golf in Lexington , Tennessee . `` The flooding brought the town to a standstill . No one could get in and no one could get out , '' he said . `` Many homes , vehicles and entire neighborhoods either were or still are under water . '' CNN iReporter Jennifer Alter said her dad helped her push her car out after she got stuck on Christmasville Road in Jackson , Tennessee , on the way to work early Saturday morning . `` We went back to check it a few hours later and the road was gone , '' she said . Lacy said one shelter had opened at Lipscomb University , and officials planned to open others . The rain is expected to continue into Sunday morning , she said . Heidt said floodwaters were expected to crest around 11 p.m. CT ( midnight ET ) Saturday . The weather service has reported record flooding at Mill Creek , near Antioch , Tennessee . CNN 's Jacqui Jeras and Greg Morrison contributed to this report .
NEW : 33 Arkansas counties are under a tornado warning , National Weather Service says . NEW : 25 counties in Tennessee are under a tornado watch , weather service says . NEW : At least 5 people have been killed in severe flooding in central Tennessee . 6-10 inches of rain has fallen in 12 hours in Nashville area .