NEW : The casualties in Pakistan include thousands of Afghan refugees . Some 14 million people have been affected by the earthquake and floods . ` is a major disaster of enormous magnitude , '' said John Holmes , U.N. Under-Secretary-General for Humanitarian Affairs and emergency relief coordinator . The death toll stands at 1,245 , Pakistani officials say . 1,334 people have been injured ; 500 houses destroyed .
NEW : The casualties in Pakistan include thousands of Afghan refugees . Some 14 million people have been affected by the earthquake and floods . The death toll stands at 1,245 , Pakistani officials say . 1,334 people have been injured ; 500 houses destroyed .