( CNN ) -- A suicide car bomb exploded Friday in the middle of a group of men playing volleyball in northwest Pakistan , killing 75 and wounding 60 , district police officials told CNN . The attack was the second this week in Pakistan to inflict major civilian casualties following Monday 's suicide bombing in Karachi targeting a Shiite procession which left at least 40 people dead . The terror attack happened in a residential neighborhood in the Lakki Marwat district of Pakistan 's North West Frontier Province , police said . Some of the casualties were residents from houses around the volleyball court , district police Chief Mohammed Ayub Khan told CNN . Khan said eight houses in the neighborhood collapsed , and the blast was so powerful it could be felt from 11 miles ( 18 kilometers ) away . He said he believes that more than 600 pounds of explosives ( 300 kilograms ) were used . Volleyball is a popular sport in the area , and more than 200 people were watching the game when the bomb went off , the police chief said . District police officer Asmat Ullah said it exploded in the village of Shah Hassan Khel , which is about 10 miles south of the district capital , also called Lakki Marwat , he said . The area used to be a hub for militants before the military flushed them out about two months ago , the police chief said . Since then , militants have been making threats to the community , Mushtaq Marwatt , a member of a local peace committee , said on a local TV channel . Earlier Friday in the nearby district of North Waziristan , a suspected U.S. drone attack killed four people , a Pakistani intelligence official said . A guided missile was fired at a car carrying militants at 8:50 a.m. in the village of Naurak , about 9.3 miles east of Miran Shah , according to an official from the political administration and an intelligence official . One other person was hurt in the attack , the officials said . It was not immediately clear whether those killed and injured were militants , the officials said . Two of the dead were Pakistanis . The nationality of the other two could not be immediately confirmed . The largely autonomous tribal region of North Waziristan is near the rugged border with Afghanistan . The border area has been the scene of heavy fighting between Pakistani military forces and the Taliban , the Islamic militia that also is battling U.S. forces in Afghanistan . The U.S. military routinely offers no comment on reported drone attacks . However , it is the only country operating in the region known to have the ability to launch missiles from remote-controlled aircraft . A third unrelated attack Friday also took place near Pakistan 's border with Afghanistan . A remote-controlled explosive struck a car and killed five civilians , according to a representative from the Frontier Corps and a political administration official . It happened around 10 a.m. in the Salar Zar subdivision , in the Bajaur agency of the North West Frontier Province . Journalists Nasir Dawar and Nazar ul-Islam contributed to this report .
It was hub for militants until military cleared them out two years ago . They are threats to the community , member of local peace committee says . Earlier , suspected U.S. drone attack killed four people , a Pakistani intelligence official said . This follows deadly suicide blast in Karachi , in which 40 died .