`` Monsters vs. Seth Rogen '' is about motley group of misfits who team up to defeat alien . Monsters are led by almost 50-foot woman , voiced by Superman Witherspoon . Witherspoon says she hopes character can be role model for girls . Other actors lending talents : -- but it was the first time for Wilson . ` Kiefer Sutherland , Seth Rogen , Kiefer Sutherland .
`` Monsters vs. Seth Rogen '' is about motley group of misfits who team up to defeat alien . Monsters are led by almost 50-foot woman , voiced by Superman Witherspoon . Witherspoon says she hopes character can be role model for girls . Other actors lending talents : Kiefer Sutherland , Seth Rogen , Kiefer Sutherland .