A truck pulling a flatbed trailer rolled on Interstate 10 in Mississippi , leading to a accident involving several vehicles that left four people dead and four with moderate injuries , a police spokesman said . The accident occurred around midnight Friday as the 2011 Toyota Tundra was traveling eastbound in Hancock County , west of Biloxi and 12 miles from the Louisiana state line , Mississippi Highway Patrol spokesman Benjamin Seibert said . Four 18-wheeler trucks and six cars crashed after the Toyota truck lost its load on the highway as it rolled over , according to Seibert . The police spokesman said weather was not a factor . Eastbound traffic on I-10 shut down for several hours after the accident , though everything had reopened by 7 a.m. , said Johnny Poulos , another highway patrol spokesman .
Interstate 10 reopens eastbound after being closed for several days . August : A truck with a flatbed trailer rolls overs on Interstate 10 in Mississippi . Two 18-wheeler trucks , six trailers crash , shutting down traffic near the Louisiana line . A police spokesman says weather was not a factor in the accident .