Researchers from the University of California have published a pair of studies in which they change human cells within the body with so-called "notch" molecules in order to make them more adept at fighting cancer, programming cells to sense "anything in the human body and responding by activating any gene we choose". The research is part of an ongoing project called CRISPR-Cas9 that aims to use this new technology for genome editing as well as other medical applications.
Researchers from the University of California have published a pair of studies in which they change human cells within the body with so-called "notch" molecules in order to make them more adept at fighting cancer, programming cells to sense "anything in the human body and responding by activating any gene we choose". The scientists hope to replicate the successes seen with CAR-T cells in leukemia with solid tumours via these notch cells, and increasingly engineer the body to just target the cancerous cells.