Reversing or treating senescent cells, which adversely affect cells around them to cause heart failure, may be possible, according to researchers from Newcastle University, the US and France. The research was carried out by scientists at Newcastle University in collaboration with colleagues from France and Germany. While not dead, the cells do not function properly and cause surrounding cells to become senescent. The research, funded by the British Heart Foundation, found that some cells become senescent from stress rather than through cell division. The researchers are now examining how senescent cells found after a heart attack could be removed.
Reversing or treating senescent cells, which adversely affect cells around them to cause heart failure, may be possible, according to researchers from Newcastle University, the US and France. These 'zombie' cells occur throughout the body as it ages. While not dead, the cells do not function properly and cause surrounding cells to become senescent. The research, funded by the British Heart Foundation, found that some cells become senescent from stress rather than through cell division. The researchers are now examining how senescent cells found after a heart attack could be removed.