By 1827, Laplace was using least squares methods to address ANOVA problems regarding measurements of atmospheric tides.
baɪ wˈʌn θˈaʊzənd ˈeɪthˈʌndɹɪd twˈɛnti sˈɛvən, lˈæpleɪs wʌz jˈuːzɪŋ lˈiːst skwˈɛɹz mˈɛθədz tʊ ɐdɹˈɛs ænˈoʊvə pɹˈɑːbləmz ɹᵻɡˈɑːɹdɪŋ mˈɛʒɚmənts ʌv ˌætməsfˈɛɹɪk tˈaɪdz.