Some macromolecules such as proteins and nucleic acids can have a very large number of acidic protons.
sˌʌm mˈækɹəmˌɑːlɪkjˌuːlz sˈʌtʃ ɐz pɹˈoʊtiːnz ænd nuːklˈɪɪk ˈæsɪdz kæn hæv ɐ vˈɛɹi lˈɑːɹdʒ nˈʌmbɚɹ ʌv ɐsˈɪdɪk pɹˈoʊtɑːnz.