Through the 14th and 15th centuries, alchemists were much like Flamel: they concentrated on looking for the philosophers' stone.
θɹuː ðə fˈoːɹtiːnθ ænd fˈɪftiːnθ sˈɛntʃɚɹiz, ˈælkɪmˌɪsts wɜː mˈʌtʃ lˈaɪk flˈeɪml: ðeɪ kˈɑːnsəntɹˌeɪɾᵻd ˌɔn lˈʊkɪŋ fɚðə fɪlˈɑːsəfɚz stˈoʊn.