Heat prostration (due to decreased sweating) can occur when anticholinergics such as darifenacin are used in a hot environment.
hˈiːt pɹɑːstɹˈeɪʃən dˈuː tə dˈiːkɹiːst swˈɛɾɪŋ kæn əkˈɜː wɛn ˌæntɪkˌɑːlɪnˈɜːdʒɪks sˈʌtʃ ɐz dˈɑːɹɹaɪfnˌæsɪn ɑːɹ jˈuːzd ɪn ɐ hˈɑːt ɛnvˈaɪɹənmənt.