However, Robo-3 (Rig-1) is upregulated during growth of commissural axons during migration toward the floor plate, which sequesters Robo-1/2 inside the cell within vesicles.
haʊˈɛvɚ, ɹˈoʊboʊ θɹˈiː ɹˈɪɡ wˈʌn ɪz ˈʌpɹɪɡjˌʊleɪɾᵻd dˈʊɹɹɪŋ ɡɹˈoʊθ ʌv kəmˈɪʃɚɹəl ˈæksɑːnz dˈʊɹɹɪŋ maɪɡɹˈeɪʃən təwˈɔːɹd ðə flˈoːɹ plˈeɪt, wˌɪtʃ siːkwˈɛstɚz ɹˈoʊboʊ wˈʌn slˈæʃ tˈuː ɪnsˈaɪd ðə sˈɛl wɪðˌɪn vˈɛsɪkəlz.