hɪz bˈʊk ðə jˈuːs ænd ɐbjˈuːs ʌv təbˈækoʊ wʌz pˈʌblɪʃt ɪn wˈʌn θˈaʊzənd ˈeɪthˈʌndɹɪd fˈɪfti nˈaɪn, ænd ɪz wˈʌn ʌvðə fˈɜːst wˈɜːks tə ɹˈɛkəɡnˌaɪz bˈoʊθ ɪts ɐdˈɪktɪv nˈeɪtʃɚ ænd ɪts pətˈɛnʃəl dˈæmɪdʒ.
His book The Use and Abuse of Tobacco was published in 1859, and is one of the first works to recognise both its addictive nature and its potential damage.