tˌiːˌɑːɹkˈeɪ ɐ wʌz ɚɹˈɪdʒɪnəli klˈoʊnd fɹʌm ɐ kˈoʊlən tˈuːmɚ; ðə kˈænsɚɹ əkˈɜːd vˈaɪəɹ ɐ tɹænsloʊkˈeɪʃən, wˌɪtʃ ɹɪzˈʌltᵻd ɪnðɪ ˌæktɪvˈeɪʃən ʌvðə tˌiːˌɑːɹkˈeɪ ɐ kˈɪneɪs dəmˈeɪn.
TrkA was originally cloned from a colon tumor; the cancer occurred via a translocation, which resulted in the activation of the TrkA kinase domain.