ɡæmbˈɑːdʒɪk ɐmˈaɪd, ɐ dᵻɹˈɪvətˌɪv ʌv ɡæmbˈɑːdʒɪk ˈæsɪd, sᵻlˈɛktɪvli ˈæktᵻvˌeɪts tˌiːˌɑːɹkˈeɪ ɐ bˌʌt nˌɑːt tˌiːˌɑːɹkˈeɪ bˈiː ænd tˌiːˌɑːɹkˈeɪ sˈiː bˈoʊθ ɪnvˈɪtɹoʊ ænd ɪnvˈiːvoʊ baɪ ˌɪntɚɹˈæktɪŋ wɪððə sˌaɪɾəplˈæzmɪk dʒˈʌksteɪmmbɹˌeɪn dəmˈeɪn ʌv tˌiːˌɑːɹkˈeɪ ˈeɪ.
Gambogic amide, a derivative of gambogic acid, selectively activates TrkA (but not TrkB and TrkC) both in-vitro and in-vivo by interacting with the cytoplasmic juxtamembrane domain of TrkA.