ˌɛsˌeɪtʃˈeɪtʃ ɪz ɛkspɹˈɛst ɪn ɐ ɡɹˈeɪdiənt wɪð hˈaɪɪst kˌɑːnsəntɹˈeɪʃən lˈoʊkəlˌaɪzd ɪnðə nˈɑːɾəkˌɔːɹd ænd flˈoːɹ plˈeɪt.
Shh is expressed in a gradient with highest concentration localized in the notochord and floor plate.