hiː hɐz dɪvˈɛləpt sˈɔftwɛɹ fɔːɹ pɹˈoʊtiːn mˈɑːdəlɪŋ ænd ˌʌndɚstˈændɪŋ ðɪ ɪfˈɛkts ʌv mjuːtˈeɪʃənz ˌɔn pɹˈoʊtiːn fˈʌŋkʃən, lˈiːdɪŋ tə nˈuː ɐpɹˈoʊtʃᵻz tə stɹˈʌktʃɚɡˈaɪdᵻd ænd fɹˈæɡməntbˈeɪst lˈiːd dɪskˈʌvɚɹi.
He has developed software for protein modelling and understanding the effects of mutations on protein function, leading to new approaches to structure-guided and Fragment-based lead discovery.