ˌɔn sɛptˈɛmbɚ θˈɜːtiːn, nˈaɪntiːnhˈʌndɹɪd sˈɪksti sˈɪks, ˌɛnwˈaɪ wˈʌnhˈʌndɹɪd ɪlˈɛvən wʌz ɹˌiːɐlˈaɪnd sˈaʊθ ʌv hˈɔːpɔːdʒ tə fˈɑːloʊ ɐ slˈaɪtli mˈoːɹ wˈɛstɚli ɐlˈaɪnmənt tə ðə hˈæmlɪt ʌv ˈɪslɪp ɐlˈɔŋ dʒˈɑːʃjuːəz pˈæθ ænd ˈɪslɪp ˈævənˌuː, tˈuː stɹˈiːts ðæt ɹˈæn pˈæɹəlˌɛl tə ðə ɹˈaʊts ɚɹˈɪdʒɪnəl pˈæθ ˌɔn kˈɑːɹɹəltən ˈævənˌuː ænd wˈiːlɚ ɹˈoʊd.
On September 13, 1966, NY 111 was realigned south of Hauppauge to follow a slightly more westerly alignment to the hamlet of Islip along Joshua's Path and Islip Avenue, two streets that ran parallel to the route's original path on Carleton Avenue and Wheeler Road.