ɹˈiːsəntli, ðɛɹ hɐvbɪn ˈɛfɚts tə jˈuːz kəndˈɪʃənəl mjˌuːɾeɪdʒˈɛnᵻsˌɪs tə sᵻlˈɛktɪvli ɪnˈæktᵻvˌeɪt ðɪ ˌɛsˌeɪtʃˈeɪtʃ pˈæθweɪ spəsˈɪfɪkli ɪnðɪ ˌɛfpˈiː ɹˈiːdʒən tʊ aɪdˈɛntᵻfˌaɪ dˈɪfɹənt ɹˈoʊlz ʌv mˈɑːlɪkjˌuːlz ɪnvˈɑːlvd ɪn ˌɑːlɪɡoʊdˈɛndɹəsˌaɪt sˈɛl fˈeɪt.
Recently, there have been efforts to use conditional mutagenesis to selectively inactivate the Shh pathway specifically in the FP region to identify different roles of molecules involved in oligodendrocyte cell fate.