ɪn nˈaɪntiːnhˈʌndɹɪd nˈaɪnti nˈaɪn, hiː kˈoʊfˈaʊndᵻd ɐstˈɛks tɛknˈɑːlədʒi lˈɪmɪɾᵻd, wˌɪtʃ jˈuːzᵻz fɹˈæɡməntbˈeɪst dɹˈʌɡ dɪskˈʌvɚɹi tɛknˈɑːlədʒi tə dɪskˈʌvɚ kˈænsɚ θˌɛɹəpjˈuːɾɪks.
In 1999, he co-founded Astex Technology Ltd, which uses fragment-based drug discovery technology to discover cancer therapeutics.