hiː ɪnˈɪʃɪˌeɪɾᵻd ðə lˈændmɑːɹk wˈɜːk ɔnðə kɑːnfoːɹmˈeɪʃən ʌv mˈɛmbɹeɪn pɹˈoʊtiːnz ɪn nˈaɪntiːnhˈʌndɹɪd sˈɪksti fˈaɪv, ɹɪzˈʌltɪŋ ɪnðə pˌʌblɪkˈeɪʃən ʌv tˈuː faʊndˈeɪʃənəl pˈeɪpɚz lˈɛnɑːɹd, dʒˈɑːn ænd sˈɪŋɚ, ˈɛs.dʒˈeɪ. pɹˈoʊtiːn kɑːnfoːɹmˈeɪʃən ɪn sˈɛl mˈɛmbɹeɪn pɹˌɛpɚɹˈeɪʃənz æz stˈʌdid baɪ ˈɑːptɪkəl ɹˈoʊɾətˌoːɹi dɪspˈɜːʒən ænd sˈɜːkjʊlɚ dˈaɪkɹoʊˌɪzəm.
He initiated the landmark work on the conformation of membrane proteins in 1965, resulting in the publication of two foundational papers (Lenard, John and Singer, S.J. Protein conformation in cell membrane preparations as studied by optical rotatory dispersion and circular dichroism.