mˈɪdəl bɹˈʌðɚ lˈaɪz æt ðə nɔːɹθwˈɛst ˈɛdʒ ʌvðə mˈɪdəl bɹˈʌðɚ ɹˈiːf, hˈæfweɪ bᵻtwˌiːn ðə nˈɔːɹθ bɹˈʌðɚ ɹˈɑːk wˈʌn.θɹˈiː kˌeɪˈɛm tə ðə nɔːɹθwˈɛst ænd ðə sˈaʊθ bɹˈʌðɚ ɹˈiːf.
Middle Brother lies at the northwest edge of the Middle Brother Reef, halfway between the North Brother Rock (1.3 km to the northwest) and the South Brother Reef.