tˌiːˌɑːɹkˈeɪ ɐ hɐz fˈaɪv bˈaɪndɪŋ dəmˈeɪnz ˌɔn ɪts ˌɛkstɹəsˈɛljʊlɚ pˈoːɹʃən, ænd ðə dəmˈeɪn tˌiːˌɑːɹkˈeɪ ˈeɪdˈiː fˈaɪv fˈoʊldz ˌɪntʊ ɐn ɪmjˈuːnəɡlˌɑːbjʊlˌɪnlˈaɪk dəmˈeɪn wˌɪtʃ ɪz kɹˈɪɾɪkəl ænd ˈædɪkwət fɚðə bˈaɪndɪŋ ʌv ˌɛndʒˌiːˈɛf.
TrkA has five binding domains on its extracellular portion, and the domain TrkA-d5 folds into an immunoglobulin-like domain which is critical and adequate for the binding of NGF.