hiː hˈɛlpt dɪzˈaɪn ænd kˈɑːndʌkt ðə klˈɪnɪkəl ɪvˌæljuːˈeɪʃən ʌv nˈuː dɹˈʌɡz ænd tɹˈiːtmənt stɹˈæɾədʒiz, ɪŋklˈuːdɪŋ ðə fˈɜːst tɹˈaɪəl ʌv kˌɑːmbᵻnˈeɪʃən ˌæntɪɹˌɛtɹoʊvˈaɪɚɹəl θˈɛɹəpi ænd ðɪ ɪnˈɪʃəl stˈʌdi dˈɑːkjuːməntɪŋ ðə vˈæljuː ʌvðə stɹˈæɾədʒi ʌv ɹˈɛndɚɹɪŋ ˌeɪtʃˌaɪvˈiː ˌɑːɹɹˌɛnˈeɪ ˌʌndɪtˈɛktəbəl.
He helped design and conduct the clinical evaluation of new drugs and treatment strategies, including the first trial of combination antiretroviral therapy and the initial study documenting the value of the strategy of rendering HIV RNA undetectable.