ðə kˈælsiəm kæn ðˈɛn bˈaɪnd tʊ ænd ˈæktᵻvˌeɪt kˈɑːmədʒˌuːlɪn wˌɪtʃ ɪn tˈɜːn lˈiːdz tʊ ɛɡzˌɑːsɪtˈoʊsɪs ʌv ˈɪnsəlˌɪn vˈɛsɪkəlz lˈiːdɪŋ tʊ ˈɪnsəlˌɪn ɹᵻlˈiːs.
The calcium can then bind to and activate calmodulin which in turn leads to exocytosis of insulin vesicles leading to insulin release.