ðə dˈɪstɹɪkt ɪz nˈeɪmd ˈæftɚ ðə sˈɪɾi ʌv tˈændoʊ məhˈæmɪd kˈɑːn, fˈaʊndᵻd baɪ mˈɪɹ məhˈæmɪd kˈɑːn ʃɑːwˈɑːni tˈælpʊɹ.
The district is named after the city of Tando Muhammad Khan, founded by Mir Muhammad Khan Shahwani Talpur.