ðə sˈuːpɹəspˈaɪnəl nˈʊɹɹɑːnz ˈækt ɔnðɪ ˌɛspˌiːˈɛn ænd ɪts tˈɑːnɪk fˈaɪɚɹɪŋ, mˈɑːdʒuːlˌeɪɾɪŋ ɪts ˈækʃən ɔnðə pɚɹˈɪfɚɹəl sˌɪmpəθˈɛɾɪk tʃˈeɪn ɡˈæŋɡliə ænd ðɪ ɐdɹˈiːnəl mˈɛdʌlə.
The supraspinal neurons act on the SPN and its tonic firing, modulating its action on the peripheral sympathetic chain ganglia and the adrenal medulla.