wˈʌn mˈɛθəd ɪz tə mˈɛʒɚ lˈɪŋkɪdʒ dˌɪsˌiːkwɪlˈɪbɹiəm, ˈaɪ.ˈiː., wˈɛðɚɹ ɐ ɡˈɪvən hˈæplətˌaɪp ɪz ˌoʊvɚɹˌɛpɹᵻzˈɛntᵻd ɪnðə pˌɑːpjʊlˈeɪʃən.
One method is to measure linkage disequilibrium, i.e., whether a given haplotype is overrepresented in the population.