dˈʊɹɹɪŋ ðə mˈɪd nˈaɪntiːnhˈʌndɹɪd nˈaɪnti z, lˈændʒ bɪɡˈæn ˈædvəkˌeɪɾɪŋ fɚðə jˈuːs ʌv kˌɑːmbᵻnˈeɪʃən θˈɛɹəpi ɪnðə mˈænɪdʒmənt ʌv ˌeɪtʃˌaɪvˈiː slˈæʃ ˈeɪdz.
During the mid-1990s, Lange began advocating for the use of combination therapy in the management of HIV/AIDS.