hˌɪstɪdaɪnˈiːmiə ɪz ɐ ɹˈɛɹ ˌɔːɾoʊsˈoʊməl ɹᵻsˈɛsɪv mˌɛɾəbˈɑːlɪk dɪsˈoːɹdɚ kˈɔːzd baɪ ɐ dᵻfˈɪʃənsi ʌvðɪ ˈɛnzaɪm hˈɪstɪdˌeɪs.
Histidinemia is a rare autosomal recessive metabolic disorder caused by a deficiency of the enzyme histidase.