ɪnðə kˈɑːntɛkst ʌv dˌaɪəɡnˈoʊsɪs ænd tɹˈiːtmənt ʌv slˈiːp dɪsˈoːɹdɚz, ɐ hˌaɪpoʊpnˈiː ɪz nˌɑːt kənsˈɪdɚd təbi klˈɪnɪkli sɪɡnˈɪfɪkənt ʌnlˈɛs ðɛɹ ɪz ɐ θˈɜːɾi pɚsˈɛnt ɔːɹ ɡɹˈeɪɾɚ ɹᵻdˈʌkʃən ɪn flˈoʊ lˈæstɪŋ fɔːɹ tˈɛn sˈɛkəndz ɔːɹ lˈɔŋɡɚɹ ænd ɐn ɐsˈoʊsɪˌeɪɾᵻd fˈoːɹ pɚsˈɛnt ɔːɹ ɡɹˈeɪɾɚ dᵻsˌætʃɚɹˈeɪʃən ɪnðə pˈɜːsənz ˈoʊ tˈuː lˈɛvəlz, ɔːɹ ɪf ɪt ɹɪzˈʌlts ɪn ɚɹˈaʊzəl ɔːɹ fɹˌæɡməntˈeɪʃən ʌv slˈiːp.
In the context of diagnosis and treatment of sleep disorders, a hypopnea is not considered to be clinically significant unless there is a 30% or greater reduction in flow lasting for 10 seconds or longer and an associated 4% or greater desaturation in the person's O2 levels, or if it results in arousal or fragmentation of sleep.