wˌaɪl tˌiːˌɑːɹkˈeɪ bˈiː mˈiːdɪˌeɪts ðɪ ɪfˈɛkts ʌv bˌiːdˌiːˌɛnˈɛf, ˌɛntˈiː fˈoːɹ ænd ˌɛntˈiː θɹˈiː, tˌiːˌɑːɹkˈeɪ ɐ ɪz bˈaʊnd ænd ðɛɹbˈaɪ ˈæktᵻvˌeɪɾᵻd ˈoʊnli baɪ ˌɛndʒˌiːˈɛf.
While TrkB mediates the effects of BDNF, NT-4 and NT-3, TrkA  is bound and thereby activated only by NGF.