ɪɾ ɪz sˈɪnθəsˌaɪzd baɪ ɐmˈaɪd fɔːɹmˈeɪʃən bᵻtwˌiːn ˈɛθəl pˈiːɐmˈɪnoʊbˌɛnzoʊt ænd ˈɛnbˈɛnzɔɪltˈaɪɹəsˌaɪn jˈuːzɪŋ ˈɛnmˈɛθəlmˈɔːɹfəlˌiːn ænd ˈɛθəl klˌoːɹoʊkˈɑːɹbənˌeɪt fɔːɹ ˌæktɪvˈeɪʃən.
It is synthesized by amide formation between ethyl p-aminobenzoate and N-benzoyl-tyrosine using N-methyl-morpholine and ethyl chlorocarbonate for activation.