ðɛɹˌɑːɹ sˈɛvɹəl tˌiːˌɑːɹkˈeɪ ɪnhˈɪbɪɾɚz ðæt hɐvbɪn ˌɛfdˌiːˈeɪ ɐpɹˈuːvd, ænd hɐvbɪn klˈɪnɪkli sˈiːn tə kˌaʊntɚɹˈækt ðɪ ɪfˈɛkts ʌv tˌiːˌɑːɹkˈeɪ ˌoʊvɚɹɛkspɹˈɛʃən baɪ ˈæktɪŋ æz ɐ tˌiːˌɑːɹkˈeɪ ɪnhˈɪbɪɾɚ.
There are several Trk inhibitors that have been FDA approved, and have been clinically seen to counteract the effects of Trk over-expression by acting as a Trk inhibitor.