ɪɾ ɪz mˈɪnɪməli mətˈæbəlˌaɪzd baɪ ðə sˌiːwˌaɪpˈiː fˈoːɹhˈʌndɹɪd fˈɪfti ˈɛnzaɪmz sˌiːwˌaɪpˈiː tˈuː sˈiː nˈaɪn ænd sˌiːwˌaɪpˈiː tˈuː sˈiː ˈeɪt, bˌʌt nˌɑːt baɪ sˌiːwˌaɪpˈiː θɹˈiː ˈeɪ fˈoːɹ wˌɪtʃ ɪz ɐ kˈɑːmən sˈoːɹs ʌv ˌɪntɚɹˈækʃənz ɪn ˈʌðɚ stˈætɪnz.
It is minimally metabolized by the CYP450 enzymes CYP2C9 and CYP2C8, but not by CYP3A4 (which is a common source of interactions in other statins).