ɐ ɹᵻsˈɛptɚ tˈaɪɹəsˌaɪn kˈɪneɪs ɪz ˈeɪ "tˈaɪɹəsˌaɪn kˈɪneɪs" wˌɪtʃ ɪz loʊkˈeɪɾᵻd æt ðə sˈɛljʊlɚ mˈɛmbɹeɪn, ænd ɪz ˈæktᵻvˌeɪɾᵻd baɪ bˈaɪndɪŋ əvə lˈɪɡænd tə ðə ɹᵻsˈɛptɚz ˌɛkstɹəsˈɛljʊlɚ dəmˈeɪn.
A receptor tyrosine kinase is a "tyrosine kinase" which is located at the cellular membrane, and is activated by binding of a ligand to the receptor's extracellular domain.