wˌaɪl dˈaɪəts ɐvˈɔɪdɪŋ mˈiːt, pˈoʊltɹi, tʃˈiːz, ænd ɡɹˈeɪnz kæn biː jˈuːzd ɪn ˈɔːɹdɚ tə mˌeɪk ðə jˈʊɹɹɪn mˈoːɹ ˈælkəlˌaɪn hˈaɪɚ pˈiː ˈeɪtʃ, dˈɪfɪkˌʌltiz ɪn ɪfˈɛktɪvli pɹɪdˈɪktɪŋ ðɪ ɪfˈɛkts ʌv ðiːz dˈaɪəts hæv lˈɛd tə mˌɛdɪkˈeɪʃənz, ɹˈæðɚ ðɐn dˈaɪət mˌɑːdɪfɪkˈeɪʃən, æz ðə pɹɪfˈɜːd mˈɛθəd ʌv tʃˈeɪndʒɪŋ jˈʊɹɹɪn pˈiː ˈeɪtʃ. ðə "ˈæsɪdˈæʃ" haɪpˈɑːθəsˌɪs wʌz wˈʌns kənsˈɪdɚd ɐ ɹˈɪsk fˈæktɚ fɔːɹ ˌɑːstɪˌɑːpoːɹˈoʊsɪs, ðˌoʊ ðə kˈɜːɹənt wˈeɪt ʌv saɪəntˈɪfɪk ˈɛvɪdəns dʌznˌɑːt səpˈoːɹt ðɪs haɪpˈɑːθəsˌɪs.
While diets avoiding meat, poultry, cheese, and grains can be used in order to make the urine more alkaline (higher pH), difficulties in effectively predicting the effects of these diets have led to medications, rather than diet modification, as the preferred method of changing urine pH. The "acid-ash" hypothesis was once considered a risk factor for osteoporosis, though the current weight of scientific evidence does not support this hypothesis.