bɪkˈʌz ˈɔːl ʌvðə ɹᵻpˈoːɹɾᵻd ˌɔːɾoʊɪmjˈuːn dɪzˈiːzᵻz ænd lɪmfˈoʊməz ɪnvˈɑːlv bˈiː sˈɛlz, wˈʌn haɪpˈɑːθəsˌɪs pɹəpˈoʊzᵻz ðæt ˌaɪsˌiːˈɛlz nˈæɹoʊ tˈiː sˈɛl ɹˈɛpɚtwˌɑːɹ pɹiːdɪspˈoʊzᵻz ðɪ ɪmjˈuːn sˈɪstəm tə bˈiː sˈɛl dɪsˈoːɹdɚz.
Because all of the reported autoimmune diseases and lymphomas involve B cells, one hypothesis proposes that ICL's narrow T cell repertoire predisposes the immune system to B cell disorders.