ˌɛnwˈaɪ fˈoːɹhˈʌndɹɪd fˈoːɹɾi sˈɪks bɪɡˈɪnz æɾ ɐn ˌɪntɚsˈɛkʃən wɪð ˌɛnwˈaɪ sˈɪkstiːn ɪnðə hˈɪnsdeɪl hˈæmlɪt ʌv mˈeɪplɪhˌɜːst, loʊkˈeɪɾᵻd ɐ kwˈɔːɹɾɚmˈaɪl zˈiəɹoʊ.fˈoːɹɾi kˌeɪˈɛm nˈɔːɹθ ʌv ˈɛɡzɪt twˈɛnti sˈɛvən ɔnðə sˈʌðɚn tˈɪɹ ɛkspɹˈɛsweɪ aɪ ˈeɪɾi sˈɪks ænd ˌɛnwˈaɪ sˈɛvəntˌiːn ænd ɹˈʌfli nˈɔːɹθ ʌvðə lˈɑːɹdʒɚ kəmjˈuːnᵻɾi ʌv hˈɪnsdeɪl.
NY 446 begins at an intersection with NY 16 in the Hinsdale hamlet of Maplehurst, located a quarter-mile (0.40 km) north of exit 27 on the Southern Tier Expressway (I-86 and NY 17) and roughly  north of the larger community of Hinsdale.