æz nˈoʊɾᵻd əbˌʌv dʒˈɜːmlaɪn dˌuːplɪkˈeɪʃən ʌv bɹˈækjuːɹi hˈæzbiːn aɪdˈɛntᵻfˌaɪd æz ɐ mˈeɪdʒɚ səsˌɛptəbˈɪlᵻɾi mˈɛkənˌɪzəm ɪn sˈɛvɹəl kɔːɹdˈoʊmə fˈæmɪliz.
As noted above germline duplication of brachyury has been identified as a major susceptibility mechanism in several chordoma families.