ðɪ ɐpˈoʊstˈeɪt əkˈɜːz ɪn ɐsˈɪdɪk kəndˈɪʃənz ænd ɪz ɐsˈoʊsɪˌeɪɾᵻd wɪððə ɹᵻlˈiːs ʌv kˈælsiəm ˈaɪɑːnz ænd bˈeɪɾəʃˈiːt ʌnfˈoʊldɪŋ.
The apo-state occurs in acidic conditions and is associated with the release of calcium ions and beta-sheet unfolding.