ðɪs ɹɪˈækʃən ɪz kˈæɾɐlˌaɪzd baɪ ðɪ ˈɛnzaɪm pˈaɪɹuːvˌeɪtfˈɔːɹmeɪt lˈaɪeɪs pˌiːˌɛfˈɛl, wˌɪtʃ plˈeɪz ɐn ɪmpˈoːɹtənt ɹˈoʊl ɪn ɹˈɛɡjʊlˌeɪɾɪŋ ˌænɛɹˈoʊbɪk fɜːməntˈeɪʃən ɪn ˈiː. kˈoʊli.
This reaction is catalysed by the enzyme pyruvate-formate lyase (PFL), which plays an important role in regulating anaerobic fermentation in E. coli.