hɪz səksˈɛs wʌz sˈʌtʃ ðæt wɛn dʒˈɑːn vˌiːˈaɪ kˌæntɐkuːzˈiːnoʊz wʌz fˈoːɹst tʊ ˈæbdᵻkˌeɪt baɪ hɪz sˈʌnɪnlˈɔː dʒˈɑːn vˈiː pˌæleɪəlˈoʊɡoʊz, mænwˈɛl wʌz ˈeɪbəl tə ɹᵻzˈɪst ðɪ ɐtˈɛmpt tə ɹᵻplˈeɪs hˌɪm æz ɡˈʌvɚnɚ baɪ ðɪ ˈɛmpɚɹɚz ɐpˈɔɪntiːz.
His success was such that when John VI Kantakouzenos was forced to abdicate by his son-in-law John V Palaiologos, Manuel was able to resist the attempt to replace him as governor by the emperor's appointees.