baɪ kəmpˈæɹɪsən tə dˌiːˌiːˈiː, wˌɪtʃ ɪz ɡˌæɹəntˈiːd tə fˈaɪnd ðɪ ˈɑːptɪməl səlˈuːʃən, ˌɛssˌiːˌɛmˈɛf ɪz fˈæstɚ bˌʌt lˈɛs ˈækjʊɹət ˌoʊvɚɹˈɔːl; ɪɾ ɪz sɪɡnˈɪfɪkəntli bˈɛɾɚɹ æɾ aɪdˈɛntᵻfˌaɪɪŋ kɚɹˈɛkt sˈaɪd tʃˈeɪn kɑːnfoːɹmˈeɪʃənz ɪnðə pɹˈoʊtiːnz kˈoːɹ ðɐn ɪɾ ɪz ˌɔn aɪdˈɛntᵻfˌaɪɪŋ kɚɹˈɛkt sˈɜːfɪs kɑːnfoːɹmˈeɪʃənz.
By comparison to DEE, which is guaranteed to find the optimal solution, SCMF is faster but less accurate overall; it is significantly better at identifying correct side chain conformations in the protein's core than it is on identifying correct surface conformations.