pɹˈaɪɚ tə ðə twˈɛntiəθ sˈɛntʃɚɹi, ðə sˈaɪt ʌv dʒˈɑːn ˈɛf. kˈɛnədi hˈaɪ skˈuːl wʌz pˈɑːɹt ʌvðə kˈoːɹs ʌv spˈaɪʔn̩ dˈaɪvəl kɹˈiːk wˌɪtʃ sˈɛpɚɹˌeɪɾᵻd mænhˈæʔn̩ ænd ðə bɹˈɑːŋks, wˌaɪl mˈɑːɹbəl hˈɪl wʌz dʒˌɪəɡɹˈæfɪkli pˈɑːɹt ʌv mænhˈæʔn̩.
Prior to the 20th century, the site of John F. Kennedy High School was part of the course of Spuyten Duyvil Creek which separated Manhattan and the Bronx, while Marble Hill was geographically part of Manhattan.