ˌɛsˈeɪtʃ fˈɪfti θɹˈiː bɪɡˈɪnz æɾə tˈiː ˌɪntɚsˈɛkʃən ɪn wˈɔltɚz, wˌɛɹ stˈeɪt hˈaɪweɪ fˈaɪv mˌeɪks ˌʌp ðə wˈɛstɚn ænd sˈʌðɚn lˈɛɡz ʌvðə tˈiː. ˌɛsˈeɪtʃ fˈɪfti θɹˈiː ɹˈʌnz ˈiːstwɚd fɹʌm hˈɪɹ, kɹˈɔsɪŋ ˈiːst kˈæʃ kɹˈiːk.
SH-53 begins at a T intersection in Walters, where State Highway 5 makes up the western and southern legs of the T. SH-53 runs eastward from here, crossing East Cache Creek.