ɪn wˈʌn stˈʌdi ʌv tˈuː.fˈaɪv ˌɛmdʒˈiː ˈoːɹəl dʒˈɛstɹɪnˌɑːn twˈaɪs pɜː wˈiːk ɪn wˈɪmɪn, ɪt kˈɔːzd sˈɛbɔɹˌiə ɪn sˈɛvənti wˈʌn pɚsˈɛnt, ˈækni ɪn sˈɪksti fˈaɪv pɚsˈɛnt, bɹˈɛst hˌaɪpoʊplˈæʒə ɪn twˈɛnti nˈaɪn pɚsˈɛnt, hˈɜːsuːtˌɪzəm ɪn nˈaɪn pɚsˈɛnt, ænd skˈælp hˈɛɹ lˈɔs ɪn nˈaɪn pɚsˈɛnt.
In one study of 2.5 mg oral gestrinone twice per week in women, it caused seborrhea in 71%, acne in 65%, breast hypoplasia in 29%, hirsutism in 9%, and scalp hair loss in 9%.