ɹᵻpˈoːɹɾɚ sˈɪstəmz hɐvbɪn jˈuːzd fɚðə dɪtˌɜːmᵻnˈeɪʃən ʌvðɪ ɪfˈɪʃənsi ʌv dʒˈiːn dᵻlˈɪvɚɹi sˈɪstəmz, ðɪ ˌɪntɹəsˈɛljʊlɚ lˌoʊkəlᵻzˈeɪʃən əvə dʒˈiːn pɹˈɑːdʌkt, ðə dɪtˈɛkʃən ʌv pɹˈoʊtiːnpɹˈoʊtiːn ɔːɹ pɹˈoʊtiːndˌiːˌɛnˈeɪ ˌɪntɚɹˈækʃənz, ðɪ ɪfˈɪʃənsi ʌv tɹænslˈeɪʃən ɪnˌɪʃɪˈeɪʃən sˈɪɡnəlz ænd ðə səksˈɛs ʌv məlˈɛkjʊlɚ klˈoʊnɪŋ ˈɛfɚts.
Reporter systems have been used for the determination of the efficiency of gene delivery systems, the intracellular localization of a gene product, the detection of protein-protein or protein-DNA interactions, the efficiency of translation initiation signals and the success of molecular cloning efforts.