fˈɜːst ʌv ˈɔːl, bˌiːdˌiːˌɛnˈɛf slˈæʃ tˌiːˌɑːɹkˈeɪ bˈiː sˈɪɡnəlɪŋ hˈæzbiːn ˈɪmplᵻkˌeɪɾᵻd ɪn lˈɔŋtˈɜːm mˈɛmɚɹi fɔːɹmˈeɪʃən, ðə ɹˌɛɡjʊlˈeɪʃən ʌv lˈɔŋtˈɜːm pətˌɛnʃɪˈeɪʃən, æz wˈɛl æz hˈɪpəkˌæmpəl sɪnˈæptɪk plæstˈɪsᵻɾi.
First of all, BDNF/TrkB signalling has been implicated in long-term memory formation, the regulation of long-term potentiation, as well as hippocampal synaptic plasticity.