æt ðə tˈaɪm ʌvðɪ ɚɹˈaɪvəl ʌvðɪ ˈɪŋɡlɪʃ kˈɑːlənˌɪsts ɪn wˈʌn θˈaʊzənd sˈɪkshˈʌndɹɪd sˈɛvən, ðɪ ˈɛɹiə ɚɹˈaʊnd ðə kɹˈiːk wʌz ɪnhˈæbɪɾᵻd baɪ ðə tʃɛsˈiːpiənz, ɐ ɡɹˈuːp ʌv ˈiːstɚnælɡˈɑːŋkwiən spˈiːkɪŋ nˈeɪɾɪv ɐmˈɛɹɪkənz ɐmˈɛɹɪkən ˈɪndiən ɐfˈɪlɪˌeɪɾᵻd wɪððə pˈaʊhætən kənfˈɛdɚɹəsi.
At the time of the arrival of the English colonists in 1607, the area around the creek was inhabited by the Chesepians, a group of eastern-Algonquian speaking Native Americans (American Indian) affiliated with the Powhatan Confederacy.