hiː ˈɑːɹɡjuːd ðˌɐɾɪt ɪz æn "ɪlˈuːʒən tə θˈɪŋk ðæt mˈɑːnoʊθˌɛɹəpi wɪð ˌɛni ˌæntɪɹˌɛtɹoʊvˈaɪɚɹəl ˈeɪdʒənt wɪl hæv ɐ mˈeɪdʒɚ ænd lˈæstɪŋ ˈɪmpækt ˌɔn ðɪs dɪzˈiːz" bɪkˈʌz ðə dɪvˈɛləpmənt ʌv dɹˈʌɡ ɹᵻsˈɪstəns sɪɡnˈɪfɪkəntli lˈoʊɚz ðɪ ˈɛfɪkəsi ʌv tɹˈiːtmənt.
He argued that it is an "illusion to think that monotherapy with any antiretroviral agent will have a major and lasting impact on this disease" because the development of drug resistance significantly lowers the efficacy of treatment.