ðɪ ˌɛfˌeɪdˈiː kˈɑːfæktɚ nˈɛsᵻsɚɹi fɚðə bˈeɪɾə ˌɑːksɪdˈeɪʃən ʌv fˈæɾi ˈæsɪdz ɐsˈoʊsɪˌeɪts wɪððɪ ˈælfə kˈɑːɹbən ʌv məkpˈɑːkˈoʊ ɐ kɹiːˈeɪɾɪŋ ɐn ɪɹᵻvˈɜːsᵻbəl kˈɑːmplɛks ðæt dˌɪsˈeɪbəlz ðɪ ˈɛnzaɪm.
The FAD cofactor necessary for the beta oxidation of fatty acids associates with the alpha carbon of MCPA-CoA creating an irreversible complex that disables the enzyme.