ðə səvˈɛɹᵻɾi ʌvðə dɪzˈiːz ænd ðɪ ˈaʊtkʌm ɑːɹ dɪtˈɜːmɪnd baɪ fˈæktɚz sˈʌtʃ ɐz ðə stɹˈeɪn ʌvðə vˈaɪɹəs, ðə dʒˈɛnətˌaɪp, æz wˈɛl æz ðə dˈoʊs ænd ɹˈaʊt ʌv ɪnfˈɛkʃən ʌvðə vˈaɪɹəs.
The severity of the disease and the outcome are determined by factors such as the strain of the virus, the genotype, as well as the dose and route of infection of the virus.