fˈɜːst, flˈoːɹ plˈeɪt dˌɪfɚɹˌɛnʃɪˈeɪʃən mˈeɪ biː mˈiːdɪˌeɪɾᵻd baɪ ɪndˈʌktɪv sˈɪɡnəlɪŋ fɹʌmðɪ ˌʌndɚlˈaɪɪŋ nˈɑːɾəkˌɔːɹd, ɐn ˈæksɪəl mˈɛsoʊdˌɜːm dᵻɹˈaɪvd sˈɪɡnəlɪŋ stɹˈʌktʃɚ.
First, floor plate differentiation may be mediated by inductive signaling from the underlying notochord, an axial mesoderm derived signaling structure.