ˈɛθaɪlstɹˌɛnɑːl hɐz vˈɛɹi lˈoʊ ɐfˈɪnᵻɾi fɔːɹ hjˈuːmən sˈɛɹəm sˈɛks hˈoːɹmoʊnbˈaɪndɪŋ ɡlˈɑːbjʊlˌɪn ˌɛsˌeɪtʃbˌiːdʒˈiː, lˈɛs ðɐn fˈaɪv pɚsˈɛnt ʌv ðæt ʌv tɛstˈɑːstɚɹˌoʊn ænd lˈɛs ðɐn wˈʌn pɚsˈɛnt ʌv ðæt ʌv dˌiːˌeɪtʃtˈiː.
Ethylestrenol has very low affinity for human serum sex hormone-binding globulin (SHBG), less than 5% of that of testosterone and less than 1% of that of DHT.