æz ɐ kˈɪneɪs, tˌiːˌɑːɹkˈeɪ ɐ mˈiːdɪˌeɪts ðə mˌʌltɪpəl ɪfˈɛkts ʌv ˌɛndʒˌiːˈɛf, wˌɪtʃ ɪŋklˈuːd nˈʊɹɹɑːnəl dˌɪfɚɹˌɛnʃɪˈeɪʃən, nˈʊɹɹəl pɹəlˌɪfɚɹˈeɪʃən, nˈɑːsaɪsptɚ ɹᵻspˈɑːns, ænd ɐvˈɔɪdəns ʌv pɹˈoʊɡɹæmd sˈɛl dˈɛθ.
As a kinase, TrkA mediates the multiple effects of NGF, which include neuronal differentiation, neural proliferation, nociceptor response, and avoidance of programmed cell death.