ðə blˈɛnd wˈɜːd vˈɛɹɪˌoʊm ɪz fɹʌm dʒɪnˈɛɾɪk vˈɛɹiənt“ɐ vˈɜːʒən əvə dʒˈiːn ðæt dˈɪfɚz fɹʌm ˈʌðɚ vˈɜːʒənz ʌvðə sˈeɪm dʒˈiːn wˌɪtʃ mˈeɪ ɔːɹ mˈeɪ nˌɑːɾɐv ɐn ɪfˈɛkt ˌɔn hjˈuːmən hˈɛlθ”ænd ðə sˈʌfɪks ˈoʊm“ðə kəmplˈiːt hˈoʊl əvə klˈæs ʌv sˈʌbstənsᵻz fɚɹə spˈiːsiːz ɔːɹ ɐn ˌɪndᵻvˈɪdʒuːəl”.
The blend word 'variome' is from genetic variant (“a version of a gene that differs from other versions of the same gene which may or may not have an effect on human health”) and the suffix –ome (“the complete whole of a class of substances for a species or an individual”).