haʊˈɛvɚ, ðɪs klˈoʊʒɚɹ ɪz stˈɪl ɪnˈʌf tə kˈɔːz ɐ fˌɪzɪəlˈɑːdʒɪkəl ɪfˈɛkt ˈaɪ.ˈiː., ɐn ˈɑːksɪdʒən dᵻsˌætʃɚɹˈeɪʃən ænd slˈæʃ ɔːɹ ɐn ˈɪŋkɹiːs ɪn bɹˈiːðɪŋ ˈɛfɚt tˈɜːmᵻnˌeɪɾɪŋ ɪn ɚɹˈaʊzəl.
However, this closure is still enough to cause a physiological effect i.e., an oxygen desaturation and/or an increase in breathing effort terminating in arousal.