bˈaɪndɪŋ ʌv ˈæmɪtɹˌɪptɪlˌaɪn tə tˌiːˌɑːɹkˈeɪ ɐ əkˈɜːz tə ðə lˈuːsiːn ɹˈɪtʃ ɹˈiːdʒən ˌɛlˌɑːɹɹˈɑːɹ ʌvðɪ ˌɛkstɹəsˈɛljʊlɚ dəmˈeɪn ʌvðə ɹᵻsˈɛptɚ, wˌɪtʃ ɪz dɪstˈɪŋkt fɹʌmðɪ ˌɛndʒˌiːˈɛf bˈaɪndɪŋ sˈaɪt.
Binding of amitriptyline to TrkA occurs to the Leucine Rich Region (LRR) of the extracellular domain of the receptor, which is distinct from the NGF binding site.