æt θˌɛɹəpjˈuːɾɪk dˈoʊsᵻz ðeɪ ɪŋklˈuːd: sˈɛntɹəl nˈɜːvəs sˈɪstəm tɑːksˈɪsᵻɾi, kˌɑːɹdɪoʊvˈæskjʊlɚ tɑːksˈɪsᵻɾi, tˈɛndən slˈæʃ ɑːɹtˈɪkjʊlɚ tɑːksˈɪsᵻɾi, ænd ɹˈɛɹli hɛpˈæɾɪk tɑːksˈɪsᵻɾi.
At therapeutic doses they include: central nervous system toxicity, cardiovascular toxicity, tendon / articular toxicity, and rarely hepatic toxicity.