ɪn wˈʌn stˈʌdi kəndˈʌktᵻd ˌɔn tˈuː ɹˈæt mˈɑːdəlz, ɐn ɪnhɪbˈɪʃən ʌv tˌiːˌɑːɹkˈeɪ ɐ wɪð ˌeɪˈɑːɹ sˈɛvənhˈʌndɹɪd ˈeɪɾi sˈɪks lˈɛd tʊ ɐ ɹᵻdˈʌkʃən ɪn dʒˈɔɪnt swˈɛlɪŋ, dʒˈɔɪnt dˈæmɪdʒ, ænd pˈeɪn kˈɔːzd baɪ ɪnflˈæmətˌoːɹi ɑːɹθɹˈaɪɾɪs.
In one study conducted on two rat models, an inhibition of TrkA with AR786 led to a reduction in joint swelling, joint damage, and pain caused by inflammatory arthritis.