ðɪ ɐfˈɛktᵻd dʒˈiːnz, kˌeɪˌɑːɹtˈiː fˈaɪv ænd ðə kˌeɪˌɑːɹtˈiː fˈoːɹtiːn, wˌɪtʃ ɑːɹ ɹᵻspˈɑːnsᵻbəl fɚðə kɹiːˈeɪʃən ʌv kˈɛɹɐtˌɪn fˈaɪv ænd kˈɛɹɐtˌɪn fˈoːɹtiːn pɹˈoʊtiːnz ɹᵻspˈɛktɪvli, ɑːɹ tˈaɪd tə ðə fˈoːɹ mˈeɪdʒɚ tˈaɪps ʌv ˌɛpɪdˌɜːmˈɑːləsˌɪs bʊlˈoʊsə sˈɪmplɛks.
The affected genes, KRT5 and the KRT14, which are responsible for the creation of keratin 5 and keratin 14 proteins respectively, are tied to the four major types of epidermolysis bullosa simplex.