ɪt kæn əkˈɜːɹ ˈiːðɚɹ æz ɐn ˈaɪsəlˌeɪɾᵻd mˌælfɔːɹmˈeɪʃən ɔːɹ ɪn ɐsˌoʊsɪˈeɪʃən wɪð ˈʌðɚ dᵻfˈoːɹmᵻɾiz, pɚtˈɪkjʊlɚli lˈɪm dˈiːfɛkts ɪn ɐ sˈɪndɹoʊm nˈoʊn æz ˌoːɹoʊmɐndˈɪbjʊlɚ lˈɪm hˌaɪpoʊdʒˈɛnᵻsˌɪs sˈɪndɹoʊm.
It can occur either as an isolated malformation or in association with other deformities, particularly limb defects in a syndrome known as oromandibular limb hypogenesis syndrome.