One of the things that makes me fear doing art is people interpreting it incorrectly. When I was little my mom would always read so deeply into anything I drew and call them brilliant. Except she usually got it wrong and I found it unbelievably frustrating, especially since it was usually just something meaningless or really obvious that she would go really deep into. Then I'd draw something meaningful and everyone would ignore it and pass it off as meaningless (even an art teacher yelled at me once).

Such is the life of an artist, but from personal experience that's the most frustrating part.