Aim(s): To investigate the role of EGFR and IGF1R and their possible cross-talk in BP-NET cells.
Materials and methods: Receptors expression was evaluated by Western blot in 2 BP-NET cell lines (NCI-H720, NCI-H727 cells). Cell viability and apoptosis were measured by ATPlite assay and Caspase3/7 assay, respectively. IGF1R and EGFR heterodimer formation was evaluated by immunoprecipitation (IP).
