Organyltellurium(IV) complexes of Schiff base (MeFPT = 4-methyl-N-((5-methylfuran-2-yl)methylene)aniline) derived from condensation reaction of 5-methyl furan-2-carboxaldehyde with p-toluidine having formula of type MeFPT·RTeCl3 and MeFPT·R2TeCl2 (R = 4-hydroxy-phenyl, 4-methoxyphenyl or 3-methyl-4-hydroxyphenyl) were reported. These complexes have been characterized by elemental analysis, IR, 1H NMR, 13C NMR, UV-Vis, DFT, molecular modelling and mass spectra. The experimental data demonstrated that formed Schiff base complexes behaved as bidentate ligand with R1TeCl3 and R2TeCl2 chelated by neutral N and O atoms having distorted octahedral stereochemistry in all organyltellurium(IV) complexes. Schiff base and its organyltellurium(IV) complexes exhibited considerable biological activity. The antibacterial and antifungal activity have been carried out and the results were compared with some known antibiotics.
Schiff base, 5-Methylfuran-2-carboxaldehyde, 4-Toluidine, Organyltellurium(IV) complexes, Biological activity.