For a paper published in the American Journal of Kidney Diseases, Dr. Shapiro and colleagues aimed to examine the risk for AKI after the resolution of hypertensive disorders of pregnancy. The researchers conducted a retrospective population-based cohort consisting of patients (n = 1,142,656) aged 14-50 who delivered at 20 weeks or more of gestation one or more times between April 1, 2002, and March 31, 2015, accounting for a total of 1,826,235 deliveries. The study team examined the rates of AKI after pregnancy in patients with hypertensive disorders of pregnancy compared with women with pregnancies not affected by gestational hypertension or preeclampsia.
Preeclampsia, but not gestational hypertension, correlated with an increased risk for AKI, Dr. Shapiro notes. Neither preeclampsia nor gestational hypertension were associated with AKI requiring dialysis, although this outcome was particularly infrequent. Both hypertensive disorders of pregnancy were associated with the subsequent development of ESKD. “The main takeaway is that AKI in this population is rare, but that a history of preeclampsia is linked with an increased future risk of AKI (Table),” he says.
Joshua Shapiro, MD, has indicated to Physician’s Weekly that he has no financial interests to disclose.
