Background: The medical term ―Hang over‖ literally means ―collection of symptoms that directly result from the over consumption of alcohol.‖ In chemistry, an alcohol is any organic compound in which the hydroxyl functional group (–OH) is bound to a saturated carbon atom. Alcohol in its own form is not actually toxic to our bodies, nor does it cause hangovers. The actual cause of a hangover is a toxic compound called acetaldehyde, which alcohol is converted into during detoxification. Objectives: Study to evaluate the safety and efficacy of health drink ‗DOTSHOT‘, A product of K patel Phyto Extractions Pvt. Ltd. in the treatment of hangover due to alcohol intoxication. Conclusion: Dotshot beverage increased ALDH activity, helping to metabolize / breakdown of the alcohol quickly and it shows the greatest increased ALDH activity and breakdown of acetaldehyde and promotes efficient acetaldehyde to cure the mild hangover. Also the subjects who were dosed with Test Product i.e., Dotshot had lower Blood Aldehyde Levels at 10 hours. So, this proves that DOTSHOT is safer, efficient and superior in alleviating the Alcohol induced hangover symptoms by increasing ALDH activity leading to the increase in the phase II detoxification of Alcohol.
Keywords: Acetaldehyde dehydrogenase (ALDH), Alcohol dehydrogenase (ADH), Dot shot.