id
stringlengths 1
5
| tokens
sequence | ner_tags
sequence |
---|---|---|
4268 | [
"However",
",",
"this",
"apparent",
"lack",
"of",
"response",
"to",
"the",
"secosterol",
"can",
"be",
"overcome",
"by",
"stimulation",
"of",
"B",
"lymphocytes",
"with",
"a",
"combination",
"of",
"these",
"cellular",
"activation",
"signals",
",",
"which",
"are",
"sufficient",
"to",
"lead",
"to",
"G1",
"cell",
"cycle",
"progression",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
3354 | [
"Northern",
"blot",
"analyses",
"performed",
"on",
"rat",
"and",
"mouse",
"tissues",
"have",
"detected",
"ubiquitously",
"expressed",
"Pan",
"transcripts",
",",
"but",
"the",
"abundance",
",",
"distribution",
",",
"and",
"form",
"of",
"Pan",
"proteins",
"have",
"not",
"been",
"clearly",
"defined",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0
] |
14099 | [
"These",
"insights",
"in",
"the",
"molecular",
"events",
"that",
"are",
"involved",
"in",
"TCF/LEF",
"function",
"in",
"these",
"organisms",
"may",
"eventually",
"lead",
"to",
"the",
"understanding",
"of",
"the",
"function",
"of",
"these",
"HMG",
"box",
"proteins",
"in",
"lymphoid",
"development"
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
10,
0,
0,
0
] |
16438 | [
"Induction",
"of",
"NF-kappa",
"B",
"during",
"monocyte",
"differentiation",
"is",
"associated",
"with",
"activation",
"of",
"HIV-gene",
"expression",
"."
] | [
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
11347 | [
"Our",
"results",
"showed",
"that",
"BSAP",
"plays",
"a",
"role",
"in",
"both",
"IL-4",
"-dependent",
"induction",
"and",
"CD40",
"-mediated",
"upregulation",
"of",
"human",
"epsilon",
"germline",
"transcription",
"."
] | [
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
9,
0,
0,
0,
9,
0,
0,
0,
0,
0,
1,
0,
0
] |
4739 | [
"We",
"conclude",
"that",
"the",
"kappaB",
"element",
"in",
"the",
"GM-CSF",
"promoter",
"plays",
"a",
"central",
"role",
"in",
"the",
"transcriptional",
"activation",
"of",
"the",
"endogenous",
"GM-CSF",
"gene",
"."
] | [
0,
0,
0,
0,
1,
2,
0,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
0
] |
16021 | [
"This",
"difference",
"in",
"gene",
"regulation",
"suggests",
"distinct",
"biological",
"roles",
"in",
"the",
"control",
"of",
"cell",
"proliferation",
"for",
"the",
"respective",
"proteins",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
17796 | [
"Relationship",
"between",
"Rap1",
"protein",
"phosphorylation",
"and",
"regulation",
"of",
"Ca2+",
"transport",
"in",
"platelets",
":",
"a",
"new",
"approach",
"."
] | [
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
0
] |
9853 | [
"These",
"results",
"show",
"that",
"Spi-1/",
"PU.1",
"requires",
"signals",
"emanating",
"from",
"specific",
"cytokine",
"and",
"growth",
"factor",
"receptors",
"to",
"affect",
"the",
"survival",
",",
"proliferation",
"and",
"differentiation",
"control",
"of",
"primary",
"erythroblasts",
"."
] | [
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
0
] |
2791 | [
"Since",
"clinical",
"remission",
"has",
"been",
"observed",
"in",
"a",
"significant",
"fraction",
"of",
"DLCL",
"cases",
",",
"these",
"markers",
"may",
"serve",
"as",
"critical",
"tools",
"for",
"sensitive",
"monitoring",
"of",
"minimal",
"residual",
"disease",
"and",
"early",
"diagnosis",
"of",
"relapse",
"(",
"Gribben",
"et",
"al.",
"1993",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
2170 | [
"RA",
"also",
"enhanced",
"lyn",
"mRNA",
"production",
"rapidly",
"in",
"HL-60",
",",
"indicating",
"that",
"the",
"activation",
"of",
"lyn",
"gene",
"expression",
"is",
"common",
"in",
"monocytic",
"and",
"granulocytic",
"maturation",
"of",
"myeloid",
"leukemia",
"cells",
"."
] | [
0,
0,
0,
3,
4,
0,
0,
0,
5,
0,
0,
0,
0,
0,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
0
] |
15037 | [
"A",
"second",
"messenger",
"cascade",
"involved",
"is",
"the",
"inositol",
"1",
",",
"4",
",",
"5-trisphosphate/calcium",
"pathway",
"which",
"responds",
"over",
"the",
"same",
"rapid",
"time",
"course",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
667 | [
"The",
"ZEBRA",
"activation",
"region",
"was",
"replaced",
"with",
"the",
"potent",
"acid",
"activation",
"region",
"from",
"the",
"herpes",
"simplex",
"virus",
"VP16",
"protein",
"or",
"with",
"the",
"activation",
"region",
"of",
"the",
"EBV",
"R",
"protein",
"."
] | [
0,
9,
10,
10,
0,
0,
0,
0,
0,
9,
10,
10,
0,
0,
9,
10,
10,
10,
10,
0,
0,
0,
9,
10,
0,
0,
9,
10,
10,
0
] |
10338 | [
"The",
"correlation",
"is",
"specific",
"as",
"the",
"level",
"of",
"at",
"least",
"three",
"other",
"transcription",
"factors",
"did",
"not",
"change",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0
] |
506 | [
"Upon",
"mitogenic",
"stimulation",
",",
"the",
"binding",
"activity",
"of",
"the",
"novel",
"NF-AT-binding",
"factor",
"is",
"rapidly",
"down-regulated",
"in",
"normal",
"T",
"cells",
",",
"but",
"persists",
"at",
"high",
"levels",
"in",
"Ipr",
"CD4-8-",
"T",
"cells",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
7,
8,
0,
0,
0,
0,
0,
0,
0,
5,
6,
6,
6,
0
] |
2018 | [
"An",
"in",
"vitro",
"binding",
"site",
"selection",
"procedure",
"was",
"used",
"to",
"determine",
"DNA",
"sequences",
"preferentially",
"bound",
"by",
"wild-type",
"HLF",
"and",
"chimeric",
"E2A-HLF",
"proteins",
"isolated",
"from",
"various",
"t",
"(",
"17",
";",
"19",
")",
"-bearing",
"leukemias",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
9,
10,
0,
0,
0,
0,
5,
6,
6,
6,
6,
6,
6,
6,
0
] |
7705 | [
"Thus",
",",
"STAT1",
"may",
"be",
"a",
"useful",
"target",
"in",
"the",
"development",
"of",
"new",
"immunosuppressive",
"and",
"antineoplastic",
"agents",
"."
] | [
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
12046 | [
"However",
",",
"replication",
"of",
"EBV",
"in",
"vivo",
"is",
"controlled",
"primarily",
"by",
"host",
"immune",
"mechanisms",
"selecting",
"for",
"cells",
"that",
"are",
"not",
"permissive",
"for",
"viral",
"replication",
"as",
"the",
"result",
"of",
"a",
"particular",
"set",
"of",
"transcription",
"factors",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0
] |
12070 | [
"The",
"transfected",
"cell",
"lines",
"expressed",
"elevated",
"levels",
"of",
"spi-1",
"mRNA",
"and",
"protein",
"and",
"high",
"Spi-1",
"-DNA",
"binding",
"activity",
"."
] | [
0,
5,
6,
6,
0,
0,
0,
0,
3,
4,
0,
0,
0,
0,
9,
0,
0,
0,
0
] |
9009 | [
"Stimulation",
"was",
"significantly",
"higher",
"when",
"lysates",
"were",
"heated",
"at",
"100",
"degrees",
"C",
"for",
"5",
"min",
"but",
"was",
"reduced",
"by",
"treatment",
"with",
"lysozyme",
"or",
"protease",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
9,
0
] |
3599 | [
"Thus",
",",
"constitutive",
"activation",
"of",
"Egr-1",
"gene",
"is",
"invariably",
"associated",
"with",
"unrestricted",
"expression",
"of",
"viral",
"latent",
"genes",
"in",
"all",
"group",
"III",
"EBV",
"genome",
"carrying",
"cell",
"lines",
"."
] | [
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
6,
6,
6,
6,
6,
0
] |
10499 | [
"In",
"one",
"case",
",",
"the",
"PTT",
"shift",
"was",
"explained",
"by",
"in-frame",
"splicing",
"out",
"of",
"exon",
"10",
",",
"in",
"the",
"presence",
"of",
"a",
"normal",
"exon",
"10",
"genomic",
"sequence",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
0,
0,
0,
0,
0,
0,
1,
2,
2,
2,
2,
0
] |
16976 | [
"[",
"Estrogen",
"receptor",
"content",
"of",
"peripheral",
"blood",
"lymphocytes",
"in",
"patients",
"with",
"systemic",
"lupus",
"erythematosus",
"]"
] | [
0,
9,
10,
0,
0,
7,
8,
8,
0,
0,
0,
0,
0,
0,
0
] |
9795 | [
"NF-kappa",
"B",
"activation",
"was",
"independent",
"of",
"the",
"transmembrane",
"domain",
"of",
"CD40",
",",
"suggesting",
"that",
"it",
"is",
"independent",
"of",
"p23",
",",
"a",
"molecule",
"that",
"associates",
"with",
"CD40",
"in",
"a",
"region",
"other",
"than",
"the",
"cytoplasmic",
"domain",
"."
] | [
9,
10,
0,
0,
0,
0,
0,
9,
10,
0,
9,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
9,
10,
0
] |
10385 | [
"CD40",
"is",
"an",
"important",
"signaling",
"and",
"activation",
"Ag",
"found",
"on",
"certain",
"bone",
"marrow-derived",
"cells",
"."
] | [
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
0
] |
10752 | [
"Binding",
"assays",
"using",
"125I-labeled",
"C-C",
"chemokines",
"in",
"mammalian",
"cells",
"indicated",
"that",
"CHEMR1",
"did",
"not",
"bind",
"MIP-1alpha",
",",
"RANTES",
",",
"or",
"MIP-1beta",
",",
"whereas",
"CCR-1",
"binds",
"MIP-1alpha",
"and",
"RANTES",
"."
] | [
0,
0,
0,
9,
10,
10,
0,
7,
8,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
9,
0,
9,
0
] |
9514 | [
"Finally",
",",
"recovered",
"protein",
"was",
"identified",
"as",
"genuine",
"huGATA-3",
"by",
"SDS-PAGE",
",",
"Western",
"blotting",
",",
"and",
"bandshift",
"assays",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
10563 | [
"C/EBPepsilon",
"mRNA",
"was",
"greatly",
"induced",
"during",
"in",
"vitro",
"granulocytic",
"differentiation",
"of",
"human",
"primary",
"CD34",
"(",
"+",
")",
"cells",
"."
] | [
3,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
8,
8,
8,
8,
0
] |
6982 | [
"In",
"this",
"study",
"we",
"examined",
",",
"by",
"denaturing",
"gradient-gel",
"electrophoresis",
"and",
"DNA",
"sequence",
"analysis",
",",
"the",
"possible",
"presence",
"of",
"a",
"codon",
"10",
"polymorphic",
"site",
"in",
"normal",
"oestrogen",
"target",
"organs",
"and",
"cells",
"such",
"as",
"the",
"uterus",
"(",
"myometrium",
"and",
"endometrium",
")",
",",
"in",
"the",
"placenta",
"and",
"peripheral",
"blood",
"mononuclear",
"cells",
"and",
"in",
"a",
"benign",
"uterus",
"tumour",
"(",
"leiomyoma",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0,
1,
2,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
17266 | [
"To",
"investigate",
"the",
"activity",
"of",
"a",
"single",
"transcription",
"factor",
"in",
"individual",
"viable",
"cells",
",",
"we",
"have",
"applied",
"an",
"assay",
"that",
"uses",
"the",
"fluorescence-activated",
"cell",
"sorter",
"to",
"quantitate",
"beta-galactosidase",
"(",
"beta-gal",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
7,
8,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
9,
0,
0
] |
16490 | [
"An",
"iron-responsive",
"element",
"(",
"IRE",
")",
"motif",
"has",
"been",
"identified",
"in",
"the",
"5'-untranslated",
"region",
"of",
"the",
"human",
"erythroid",
"ALAS",
"mRNA",
",",
"but",
"is",
"not",
"present",
"in",
"the",
"housekeeping",
"ALAS",
"mRNA",
"."
] | [
0,
3,
4,
4,
4,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
4,
0,
0,
0,
0,
0,
0,
0,
3,
4,
4,
0
] |
1688 | [
"Thereby",
"an",
"alternative",
"type",
"of",
"La",
"mRNA",
"was",
"identified",
"that",
"differed",
"from",
"the",
"known",
"La",
"mRNA",
"due",
"to",
"an",
"exchange",
"of",
"the",
"exon",
"1",
"."
] | [
0,
0,
0,
0,
0,
3,
4,
0,
0,
0,
0,
0,
0,
0,
3,
4,
0,
0,
0,
0,
0,
0,
1,
2,
0
] |
16212 | [
"Within",
"2",
"to",
"4",
"h",
"of",
"PMA",
"exposure",
",",
"steady",
"state",
"levels",
"of",
"TNF",
"mRNA",
"are",
"markedly",
"elevated",
"in",
"all",
"myelomonocytic",
"cell",
"lines",
"studied",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
3,
4,
0,
0,
0,
0,
0,
5,
6,
6,
0,
0
] |
8805 | [
"Specificity",
"was",
"determined",
"using",
"tetanus",
"toxoid",
",",
"endotoxin",
",",
"and",
"3",
"other",
"autoantigens",
"(",
"PBC.M2",
",",
"Sc170",
",",
"and",
"GAD",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
9,
0,
9,
0,
0,
9,
0,
0
] |
5882 | [
"While",
"CD40",
"ligation",
"strongly",
"activates",
"the",
"SAPKs",
"(",
"up",
"to",
"25-fold",
")",
",",
"it",
"does",
"not",
"affect",
"members",
"of",
"the",
"mitogen-activated",
"protein",
"kinase",
"family",
"(",
"MAPK",
";",
"ERK1",
"and",
"ERK2",
")",
"."
] | [
0,
9,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
10,
10,
0,
9,
0,
9,
0,
9,
0,
0
] |
4848 | [
"The",
"CMAT",
"protein",
"appears",
"to",
"be",
"a",
"novel",
"inducible",
"protein",
"involved",
"in",
"the",
"regulation",
"of",
"c-myb",
"expression",
"during",
"T-cell",
"activation",
"."
] | [
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0
] |
9065 | [
"Associated",
"with",
"the",
"inhibition",
"of",
"the",
"cell",
"cycle",
",",
"IL-10",
"suppressed",
"SEB",
"induction",
"of",
"interleukin-2",
"(",
"IL-2",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
9,
0,
0,
9,
0,
9,
0,
0
] |
3540 | [
"Autoregulation",
"of",
"the",
"NF-kappa",
"B",
"transactivator",
"RelA",
"(",
"p65",
")",
"by",
"multiple",
"cytoplasmic",
"inhibitors",
"containing",
"ankyrin",
"motifs",
"."
] | [
0,
0,
0,
9,
10,
10,
9,
0,
9,
0,
0,
0,
9,
10,
0,
9,
10,
0
] |
18190 | [
"Secretion",
"of",
"myeloid",
"cell-derived",
"cytokines",
"may",
"both",
"increase",
"virus",
"production",
"and",
"contribute",
"to",
"AIDS-associated",
"disorders",
"."
] | [
0,
0,
9,
10,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
11072 | [
"Examination",
"of",
"the",
"basal",
"factors",
"interacting",
"with",
"the",
"21",
"bp",
"repeat",
"elements",
"through",
"electrophoretic",
"mobility",
"shift",
"(",
"EMS",
")",
"analyses",
"has",
"demonstrated",
"the",
"formation",
"of",
"DNA-protein",
"complexes",
"common",
"to",
"each",
"of",
"the",
"21",
"bp",
"repeats",
"(",
"C1-C3",
")",
"as",
"well",
"as",
"three",
"DNA-protein",
"complexes",
"specific",
"to",
"the",
"promoter",
"proximal",
"(",
"pp",
")",
"repeat",
"(",
"U1",
"(",
"U1A/U1B",
")",
"and",
"U2",
";",
"1-4",
")",
"."
] | [
0,
0,
0,
9,
10,
0,
0,
0,
1,
2,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
1,
2,
2,
0,
1,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
1,
2,
2,
2,
2,
2,
0,
1,
0,
1,
0,
0,
1,
0,
0,
0,
0
] |
6741 | [
"The",
"Wilms",
"'",
"tumor",
"gene",
"(",
"WT1",
")",
"encodes",
"a",
"transcription",
"factor",
"of",
"the",
"zinc",
"finger",
"type",
"."
] | [
0,
1,
2,
2,
2,
0,
1,
0,
0,
0,
9,
10,
0,
0,
9,
10,
10,
0
] |
874 | [
"Fifty-three",
"cases",
"(",
"11",
"AML",
"M4Eo",
";",
"1",
"AML",
"M4",
"with",
"atypical",
"abnormal",
"eosinophils",
"(",
"AML",
"M4",
"``",
"Eo",
"''",
")",
";",
"29",
"AML",
"M4",
";",
"8",
"AML",
"M5",
";",
"3",
"CMML",
";",
"and",
"1",
"AML",
"M2",
"with",
"eosinophilia",
")",
"were",
"analyzed",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
14986 | [
"Our",
"results",
"are",
"consistent",
"with",
"the",
"view",
"that",
"the",
"DNA-binding",
"activity",
"LEF1/BCF1",
"is",
"a",
"homodimer",
"of",
"E2A",
"proteins",
";",
"the",
"selective",
"appearance",
"of",
"this",
"putative",
"cell-specific",
"transcription",
"factor",
"in",
"B",
"lymphoid",
"cells",
"seems",
"to",
"be",
"attributable",
",",
"at",
"least",
"in",
"part",
",",
"to",
"the",
"elevated",
"E2A",
"protein",
"concentrations",
"in",
"these",
"cells",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
9,
10,
10,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0
] |
15607 | [
"PLB-985",
"cells",
"represent",
"a",
"bipotential",
"myelomonoblastic",
"cell",
"population",
"capable",
"of",
"either",
"granulocytic",
"or",
"monocytic",
"differentiation",
"after",
"induction",
"with",
"appropriate",
"inducers",
"."
] | [
5,
6,
0,
0,
5,
6,
6,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
14980 | [
"The",
"E2A",
"gene",
"encodes",
"transcription",
"factors",
"of",
"the",
"helix-loop-helix",
"family",
"that",
"are",
"implicated",
"in",
"cell-specific",
"gene",
"expression",
"as",
"part",
"of",
"dimeric",
"complexes",
"that",
"interact",
"with",
"E",
"box",
"enhancer",
"elements",
"."
] | [
0,
1,
2,
0,
9,
10,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
1,
2,
2,
2,
0
] |
10531 | [
"We",
"have",
"characterized",
"the",
"expression",
"of",
"STAT",
"and",
"IFN",
"regulatory",
"factor",
"(",
"IRF",
")",
"family",
"transcription",
"factors",
"in",
"primary",
"human",
"blood",
"mononuclear",
"cells",
"and",
"macrophages",
"in",
"response",
"to",
"IFN-alpha",
"and",
"IFN-gamma",
"stimulation",
"."
] | [
0,
0,
0,
0,
0,
0,
9,
10,
10,
10,
10,
10,
10,
10,
10,
10,
10,
0,
7,
8,
8,
8,
8,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0
] |
8807 | [
"HLA",
"Class",
"II",
"dependency",
"was",
"investigated",
"using",
"anti-Class",
"II",
"monoclonal",
"antibodies",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
10,
10,
10,
0
] |
9320 | [
"The",
"described",
"conditions",
"which",
"inhibited",
"or",
"prevented",
"the",
"activation",
"of",
"the",
"IL-1RI-associated",
"kinase",
"similarly",
"impaired",
"the",
"activation",
"of",
"NF-kappa",
"B",
"in",
"EL4",
"cells",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
9,
10,
0,
5,
6,
0
] |
11111 | [
"Transient",
"cotransfection",
"of",
"tat",
"cDNA",
"in",
"sense",
"orientation",
"(",
"tat/S",
")",
",",
"together",
"with",
"a",
"plasmid",
"containing",
"the",
"c-fos",
"promoter",
"(",
"FC3",
",",
"from-",
"711",
"to",
"+42",
")",
"in",
"front",
"of",
"the",
"bacterial",
"chloramphenicol",
"acetyltransferase",
"(",
"CAT",
")",
"gene",
"significantly",
"enhanced",
"CAT",
"activity",
"in",
"Jurkat",
"cells",
"activated",
"by",
"the",
"addition",
"of",
"15",
"%",
"fetal",
"calf",
"serum",
"(",
"FCS",
")",
"or",
"5",
"micrograms/mL",
"phytohemagglutinin",
"plus",
"10",
"(",
"-7",
")",
"mol/L",
"phorbol",
"myristate",
"acetate",
"(",
"PMA",
")",
"and",
"U937",
"cells",
"activated",
"by",
"15",
"%",
"FCS",
"or",
"10",
"(",
"-7",
")",
"mol/L",
"PMA",
"."
] | [
0,
0,
0,
1,
2,
0,
0,
0,
0,
1,
0,
0,
0,
0,
0,
1,
0,
0,
1,
2,
0,
1,
0,
0,
1,
2,
2,
0,
0,
0,
0,
0,
1,
2,
2,
2,
2,
2,
2,
0,
0,
9,
0,
0,
5,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
10141 | [
"Here",
",",
"we",
"show",
"that",
"the",
"DBF",
"site",
"is",
"an",
"interferon-responsive",
"factor",
"(",
"IRF",
")",
"binding",
"site",
"and",
"that",
"the",
"AP3-L",
"motif",
"binds",
"the",
"T-cell-specific",
"factor",
"NF-AT",
"."
] | [
0,
0,
0,
0,
0,
0,
1,
2,
0,
0,
1,
2,
2,
2,
2,
2,
2,
0,
0,
0,
1,
2,
0,
0,
9,
10,
9,
0
] |
7221 | [
"There",
"was",
",",
"however",
",",
"a",
"significant",
"difference",
"in",
"the",
"amounts",
"of",
"the",
"nuclear",
"protein",
",",
"REF-1",
"(",
"which",
"regulates",
"AP-1",
"DNA",
"binding",
"by",
"altering",
"the",
"redox",
"status",
"of",
"FOS",
"and",
"JUN",
"proteins",
")",
",",
"in",
"alveolar",
"macrophages",
"compared",
"with",
"monocytes",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
9,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
9,
10,
0,
0,
0,
7,
8,
0,
0,
7,
0
] |
13725 | [
"Alveolar",
"macrophages",
"play",
"an",
"important",
"role",
"in",
"host",
"defense",
"and",
"in",
"other",
"types",
"of",
"inflammatory",
"processes",
"in",
"the",
"lung",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
10984 | [
"The",
"predictive",
"protein-coding",
"region",
"of",
"RP1",
"had",
"a",
"significant",
"homology",
"to",
"members",
"of",
"the",
"recently",
"found",
"adenomatous",
"polyposis",
"coli",
"(",
"APC",
")",
"protein-binding",
"EB1",
"gene",
"family",
",",
"which",
"codes",
"for",
"yet",
"unknown",
"protein",
"(",
"s",
")",
"."
] | [
0,
1,
2,
2,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
2,
2,
2,
2,
2,
2,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
6100 | [
"Dephosphorylation",
"of",
"ZAP-70",
"and",
"inhibition",
"of",
"T",
"cell",
"activation",
"by",
"activated",
"SHP1",
"."
] | [
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0
] |
13355 | [
"Here",
"we",
"show",
"that",
"the",
"binding",
"of",
"calcineurin",
"to",
"NFAT",
"is",
"substantially",
"increased",
"when",
"calcineurin",
"is",
"activated",
"with",
"calmodulin",
"and",
"calcium",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
0,
9,
0,
0,
0,
0,
9,
0,
0,
0,
9,
0,
0,
0
] |
9297 | [
"We",
"demonstrate",
"that",
"mRNAs",
"for",
"all",
"three",
"of",
"these",
"regulatory",
"factors",
"are",
"expressed",
"in",
"fetal",
"blood",
"cells",
"by",
"the",
"27th",
"week",
"of",
"gestation",
"and",
"in",
"term",
"cord",
"bloods",
"."
] | [
0,
0,
0,
3,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
12209 | [
"Mutational",
"analysis",
"of",
"UAS1",
"sequences",
"combined",
"with",
"in",
"vitro",
"bandshift",
"assays",
"revealed",
"the",
"presence",
"of",
"three",
"binding",
"sites",
"for",
"cellular",
"factors",
"in",
"this",
"region",
"."
] | [
0,
0,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
0,
9,
10,
0,
0,
0,
0
] |
6430 | [
"When",
"compared",
"with",
"normal",
"cells",
",",
"the",
"activation",
"of",
"NF-kappa",
"B",
"activity",
"in",
"SLE",
"patients",
"was",
"significantly",
"decreased",
"in",
"SLE",
",",
"but",
"not",
"in",
"RA",
",",
"patients",
"."
] | [
0,
0,
0,
7,
8,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
14601 | [
"Subsequently",
",",
"I",
"kappa",
"B-alpha",
"mRNA",
"and",
"protein",
"levels",
"are",
"quickly",
"induced",
"by",
"the",
"activated",
"NF-kappa",
"B",
"."
] | [
0,
0,
3,
4,
4,
4,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0
] |
16198 | [
"The",
"present",
"work",
"demonstrates",
"that",
"the",
"glucocorticoid",
"dexamethasone",
"inhibits",
"TPA-induced",
"increases",
"in",
"c-jun",
"and",
"c-fos",
"mRNA",
"levels",
"in",
"U-937",
"leukemia",
"cells",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
6,
0
] |
10659 | [
"Expression",
"plasmids",
"encoding",
"regions",
"of",
"RFX5",
"fused",
"to",
"the",
"GAL4",
"DNA",
"binding",
"domain",
"activated",
"transcription",
"from",
"a",
"reporter",
"construct",
"containing",
"GAL4",
"sites",
"in",
"a",
"cotransfection",
"assay",
"in",
"the",
"Raji",
"human",
"B",
"cell",
"line",
"."
] | [
1,
2,
0,
0,
0,
9,
0,
0,
0,
9,
10,
10,
10,
0,
0,
0,
0,
0,
0,
0,
1,
2,
0,
0,
0,
0,
0,
0,
5,
6,
6,
6,
6,
0
] |
4122 | [
"The",
"son",
"of",
"the",
"unaffected",
"twin",
"sister",
"was",
"shown",
"to",
"be",
"hemizygous",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
5488 | [
"HTLV-I",
"encodes",
"a",
"potent",
"transactivator",
"protein",
"termed",
"Tax",
"that",
"appears",
"to",
"play",
"an",
"important",
"role",
"in",
"the",
"process",
"of",
"T-cell",
"immortalization",
"."
] | [
0,
0,
0,
0,
9,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
14558 | [
"Induction",
"of",
"CD8",
"antigen",
"and",
"suppressor",
"activity",
"by",
"glucocorticoids",
"in",
"a",
"CEM",
"human",
"leukemic",
"cell",
"clone",
"."
] | [
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
5,
6,
6,
6,
6,
0
] |
7729 | [
"These",
"studies",
"therefore",
"suggest",
"that",
"basal",
"level",
"GR",
"expression",
"is",
"inadequate",
"to",
"mediate",
"glucocorticoid-induced",
"apoptosis",
"in",
"glucocorticoid-sensitive",
"T",
"cells",
"and",
"that",
"positive",
"autoregulation",
"is",
"a",
"necessary",
"component",
"of",
"this",
"process",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
17435 | [
"We",
"therefore",
"speculate",
"that",
"N-Oct-3",
"and",
"other",
"N-Oct",
"factors",
"have",
"a",
"specific",
"role",
"in",
"gene",
"expression",
"in",
"cells",
"of",
"the",
"nervous",
"system",
"."
] | [
0,
0,
0,
0,
9,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
1504 | [
"Inclusion",
"of",
"this",
"LTR",
"in",
"recombinant",
"SIVs",
"also",
"resulted",
"in",
"a",
"two-",
"to",
"threefold",
"rise",
"in",
"the",
"extent",
"of",
"cellular",
"proliferation",
"that",
"was",
"induced",
"in",
"quiescent",
"simian",
"peripheral",
"blood",
"mononuclear",
"cells",
"."
] | [
0,
0,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
6,
6,
6,
6,
0
] |
15295 | [
"It",
"appears",
"that",
"a",
"basal",
"redox",
"equilibrium",
"tending",
"toward",
"oxidation",
"is",
"a",
"prerequisite",
"for",
"full",
"activation",
"of",
"transduction",
"pathways",
"regulating",
"the",
"activity",
"of",
"NF-kappa",
"B-dependent",
"genes",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
2,
0
] |
1781 | [
"Furthermore",
",",
"the",
"results",
"obtained",
"with",
"TNF",
"alpha",
"proved",
"that",
"NF-kappa",
"B",
"activation",
"was",
"not",
"sufficient",
"for",
"induction",
"of",
"neuroblastoma",
"differentiation",
"."
] | [
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0
] |
6559 | [
"When",
"a",
"therapy",
"proves",
"effective",
",",
"do",
"clinicians",
"truly",
"know",
"how",
"it",
"works",
"?",
"Even",
"with",
"a",
"therapy",
"as",
"specific",
"as",
"anti-TNF",
"antibody",
",",
"it",
"is",
"not",
"clear",
"if",
"the",
"benefit",
"is",
"attributable",
"to",
"simple",
"binding",
"and",
"clearance",
"of",
"TNF-alpha",
"or",
"to",
"binding",
"on",
"the",
"cell",
"surface",
"and",
"subsequent",
"deletion",
"of",
"the",
"activated",
"macrophage",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
0
] |
7122 | [
"The",
"GTPase",
"Rho",
"is",
"known",
"to",
"mediate",
"the",
"assembly",
"of",
"integrin-containing",
"focal",
"adhesions",
"and",
"actin",
"stress",
"fibers",
"."
] | [
0,
9,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
1837 | [
"A",
"fragment",
"of",
"Oct-2",
"containing",
"POUHD",
"and",
"an",
"adjoining",
"linker",
"was",
"expressed",
"in",
"Escherichia",
"coli",
"and",
"characterized",
"by",
"three-dimensional",
"nuclear",
"magnetic",
"resonance",
"(",
"3D-NMR",
")",
"spectroscopy",
"."
] | [
0,
0,
0,
9,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
15424 | [
"The",
"mitogen-induced",
"increase",
"of",
"c-Fos",
"and",
"c-Jun",
"immunoreactivity",
"was",
"inhibited",
"by",
"H-7",
",",
"a",
"kinase",
"inhibitor",
"with",
"relatively",
"high",
"specificity",
"for",
"PKC",
",",
"and",
"less",
"efficiently",
"by",
"H-8",
",",
"a",
"structurally",
"related",
"kinase",
"inhibitor",
"less",
"active",
"on",
"PKC",
",",
"but",
"more",
"active",
"on",
"cyclic",
"nucleotide-dependent",
"kinases",
"."
] | [
0,
0,
0,
0,
9,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
3690 | [
"We",
"suggest",
"that",
"HIV-1",
"infection",
"of",
"myeloid",
"cells",
"induces",
"IFN",
"production",
"and",
"PKR",
"activity",
",",
"which",
"in",
"turn",
"contribute",
"to",
"enhanced",
"IkappaBalpha",
"phosphorylation",
"and",
"subsequent",
"degradation",
"."
] | [
0,
0,
0,
0,
0,
0,
7,
8,
0,
9,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0
] |
11591 | [
"One",
"of",
"these",
"NFAT-like",
"elements",
"encompassed",
"overlapping",
"Oct-",
"and",
"NFATp/c-binding",
"sites",
",",
"which",
"functioned",
"in",
"a",
"highly",
"synergistic",
"manner",
"."
] | [
0,
0,
0,
1,
2,
0,
0,
1,
2,
2,
2,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
6373 | [
"Peripheral",
"blood",
"monocytes",
"were",
"isolated",
"by",
"density",
"centrifugation",
"methods",
"with",
"a",
"purity",
"of",
">",
"90",
"%",
"and",
"were",
"cultured",
"in",
"RPMI",
"1640",
"medium",
"."
] | [
7,
8,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
2508 | [
"Multicolor",
"flow",
"cytometric",
"assays",
"confirmed",
"the",
"coexpression",
"of",
"myeloid",
"(",
"CD33",
",",
"CD13",
",",
"CD15",
")",
"and",
"NK",
"cell-associated",
"(",
"CD56",
")",
"antigens",
"in",
"each",
"case",
",",
"whereas",
"reverse",
"transcription",
"polymerase",
"chain",
"reaction",
"(",
"RT-PCR",
")",
"assays",
"confirmed",
"the",
"identity",
"of",
"CD56",
"(",
"neural",
"cell",
"adhesion",
"molecule",
")",
"in",
"leukemic",
"blasts",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
10,
10,
10,
10,
10,
10,
10,
10,
10,
10,
10,
10,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
9,
10,
10,
10,
0,
0,
7,
8,
0
] |
1131 | [
"Human",
"RXR",
"alpha",
"was",
"significantly",
"expressed",
"in",
"U937",
"and",
"THP-1",
"cells",
",",
"weakly",
"expressed",
"in",
"H9",
"cells",
"and",
"not",
"detectable",
"in",
"CEM",
"cells",
"."
] | [
9,
10,
10,
0,
0,
0,
0,
5,
6,
6,
6,
0,
0,
0,
0,
5,
6,
0,
0,
0,
0,
5,
6,
0
] |
16545 | [
"Similar",
"DNA",
"binding",
"activity",
"was",
"detected",
"in",
"a",
"variety",
"of",
"virus-uninfected",
"human",
"T",
"cell",
"lines",
"and",
"HeLa",
"cells",
"by",
"means",
"of",
"a",
"gel",
"mobility",
"shift",
"assay",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
5,
6,
6,
6,
6,
0,
5,
6,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
11159 | [
"First",
",",
"previous",
"studies",
"have",
"shown",
"this",
"integrin",
"to",
"be",
"particularly",
"prone",
"to",
"proteolytic",
"regulation",
"of",
"its",
"function",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
5385 | [
"Globin",
"gene",
"switching",
"."
] | [
0,
0,
0,
0
] |
16412 | [
"Surprisingly",
",",
"multimers",
"of",
"kappa",
"1-kappa",
"3",
"can",
"confer",
"PMA",
"inducibility",
"on",
"a",
"heterologous",
"promoter",
"in",
"a",
"B",
"(",
"Raji",
")",
",",
"but",
"not",
"a",
"T",
"(",
"HUT78",
")",
"cell",
"line",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
0,
0,
5,
6,
6,
6,
6,
6,
6,
6,
6,
6,
6,
6,
6,
6,
0
] |
5283 | [
"With",
"these",
"clones",
",",
"we",
"demonstrated",
"that",
"NFAT",
"activation",
"induced",
"by",
"phorbol",
"12-myristate",
"13-acetate",
"and",
"ionomycin",
"was",
"inhibited",
"by",
"both",
"cyclosporin",
"A",
"(",
"CsA",
")",
"(",
"IC50",
"=",
"8",
"nM",
")",
"and",
"FK506",
"(",
"IC50",
"=",
"160",
"pM",
")",
",",
"presumably",
"by",
"inhibition",
"of",
"calcineurin",
"activity",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0
] |
10501 | [
"Three",
"3rd",
"base",
"substitution",
"polymorphisms",
"were",
"also",
"detected",
"during",
"direct",
"sequencing",
"of",
"PCR",
"products",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
0
] |
6548 | [
"This",
"observation",
"is",
"consistent",
"with",
"the",
"detection",
"of",
"normal",
"CD40",
"-induced",
"monocyte",
"activation",
"in",
"patients",
"with",
"CD40",
"ligand+",
"hyper",
"IgM",
"syndrome",
"in",
"whom",
"a",
"defect",
"in",
"CD40",
"-induced",
"B",
"cell",
"activation",
"has",
"been",
"reported",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
9,
0,
0,
9,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0
] |
15661 | [
"Together",
",",
"these",
"findings",
"suggest",
"that",
"the",
"nuclear",
"localization",
"signal",
"and",
"transactivation",
"domain",
"of",
"NF-kappa",
"B",
"p65",
"constitute",
"a",
"bipartite",
"system",
"that",
"is",
"critically",
"involved",
"in",
"the",
"inhibitory",
"function",
"of",
"I",
"kappa",
"B/MAD-3",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
9,
10,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
10,
0
] |
6049 | [
"We",
"have",
"investigated",
"mechanisms",
"and",
"consequences",
"of",
"STAT5",
"activation",
"through",
"the",
"human",
"IL-4",
"receptor",
"(",
"IL-4R",
")",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
9,
10,
10,
0,
9,
0,
0
] |
36 | [
"We",
"demonstrate",
"that",
"the",
"transcriptional",
"activity",
"of",
"GATA-1",
"is",
"strongly",
"repressed",
"by",
"the",
"estrogen",
"receptor",
"(",
"ER",
")",
"in",
"a",
"ligand-dependent",
"manner",
"and",
"that",
"this",
"repression",
"is",
"reversible",
"in",
"the",
"presence",
"of",
"4-hydroxytamoxifen",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
9,
10,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
5446 | [
"The",
"distribution",
"of",
"this",
"integral",
"membrane",
"protein",
"is",
"restricted",
"to",
"certain",
"tissues",
"where",
"its",
"level",
"of",
"expression",
"is",
"modulated",
"by",
"multiple",
"exogenous",
"stimuli",
"."
] | [
0,
0,
0,
0,
9,
10,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
15812 | [
"Furthermore",
",",
"in",
"vitro",
"mutagenesis",
"experiments",
"demonstrated",
"that",
"inducible",
"interleukin-2",
"enhancer",
"function",
"requires",
"the",
"presence",
"of",
"either",
"EBS1",
"or",
"EBS2",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
1,
2,
0,
0,
0,
0,
0,
0,
0,
0,
1,
0
] |
3937 | [
"In",
"the",
"search",
"for",
"a",
"potential",
"treatment",
",",
"we",
"have",
"tested",
"tyloxapol",
",",
"an",
"alkylaryl",
"polyether",
"alcohol",
"polymer",
"detergent",
"previously",
"used",
"as",
"a",
"mucolytic",
"agent",
"in",
"adult",
"chronic",
"bronchitis",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
6645 | [
"Our",
"findings",
"demonstrate",
"an",
"essential",
"role",
"of",
"NF-kappa",
"B",
"in",
"survival",
"of",
"naive",
"PBL",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
7,
8,
0
] |
10000 | [
"Indeed",
",",
"addition",
"of",
"inhibitors",
"of",
"NF-kappa",
"B",
"activation",
"pyrrolidine",
"dithiocarbamate",
"(",
"PDTC",
")",
",",
"to",
"the",
"lymphocytes",
"of",
"the",
"chemically-exposed",
"group",
"was",
"capable",
"of",
"inhibiting",
"programmed",
"cell",
"death",
"by",
"40",
"%",
"."
] | [
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
5337 | [
"The",
"IL-2",
"enhancer",
"contains",
"a",
"functional",
"motif",
"named",
"CD28",
"response",
"element",
"(",
"CD28RE",
")",
"that",
"serves",
"a",
"role",
"as",
"a",
"target",
"for",
"mitogenic",
"T",
"cell",
"activation",
"signals",
"."
] | [
0,
9,
0,
0,
0,
0,
0,
0,
1,
2,
2,
0,
1,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
4653 | [
"E3330",
"decreased",
"activated",
"NF-kappa",
"B",
"in",
"nuclei",
",",
"suggesting",
"that",
"E3330",
"inhibits",
"NF-kappa",
"B",
"activation",
"and/or",
"translocation",
"of",
"the",
"nuclei",
"."
] | [
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
0,
0,
0,
0
] |
12975 | [
"The",
"high",
"concentration",
"of",
"foreign",
"antigen",
"in",
"the",
"lumen",
"of",
"the",
"gastrointestinal",
"tract",
"is",
"separated",
"from",
"the",
"underlying",
"lymphocytes",
"by",
"a",
"single",
"cell",
"layer",
"of",
"polarized",
"epithelium",
"."
] | [
0,
0,
0,
0,
9,
10,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
18312 | [
"The",
"induction",
"of",
"gene",
"transcription",
"in",
"response",
"to",
"gamma",
"interferon",
"is",
"impaired",
"in",
"mononuclear",
"phagocytes",
"infected",
"with",
"Leishmania",
"donovani",
",",
"and",
"the",
"mechanisms",
"involved",
"are",
"not",
"fully",
"understood",
"."
] | [
0,
0,
0,
0,
0,
0,
0,
0,
9,
10,
0,
0,
0,
7,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0
] |
9223 | [
"Inhibition",
"of",
"PI3K",
"inhibits",
"phosphorylation",
"of",
"Rb",
",",
"induction",
"of",
"cyclin",
"D3",
",",
"and",
"degradation",
"of",
"p27kip1",
"."
] | [
0,
0,
9,
0,
0,
0,
9,
0,
0,
0,
9,
10,
0,
0,
0,
0,
9,
0
] |
1474 | [
"A",
"newly",
"established",
"megakaryoblastic/erythroid",
"cell",
"line",
"that",
"differentiates",
"to",
"red",
"cells",
"in",
"the",
"presence",
"of",
"erythropoietin",
"and",
"produces",
"platelet-like",
"particles",
"."
] | [
0,
0,
0,
5,
6,
6,
0,
0,
0,
7,
8,
0,
0,
0,
0,
9,
0,
0,
7,
8,
0
] |
16094 | [
"These",
"diurnal",
"variations",
"in",
"GR",
"might",
"serve",
"to",
"coordinate",
"the",
"reactivity",
"of",
"the",
"target",
"cells",
"to",
"cortisol",
"because",
"the",
"diurnal",
"rhythms",
"of",
"a",
"GR",
"-mediated",
"response",
",",
"the",
"fractional",
"inhibition",
"of",
"chemotactic",
"migration",
"rate",
"of",
"polymorphonuclear",
"leukocytes",
"by",
"cortisol",
",",
"were",
"found",
"to",
"be",
"synchronous",
"with",
"those",
"of",
"GR",
"."
] | [
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
7,
8,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
0,
9,
0
] |
Subsets and Splits