Over the centuries, disagreements separated Western Christianity from the various forms of Eastern Christianity: first from East Syrian Christianity after the Council of Ephesus (431), then from that of Oriental Orthodoxy after the Council of Chalcedon (451), and then from Eastern Orthodoxy with the East-West Schism of 1054.
Today, the geographical distinction between Western and Eastern Christianity is now much less absolute, due to the great migrations of Europeans across the globe, as well as the work of missionaries worldwide over the past five centuries.