De La Salle College was established on June 15, 1911 by the Brothers of the Christian Schools opened their first school in the Philippines on Calle Nozaleda in Paco, Manila at the request of the then American Archbishop of Manila Jeremiah James Harty [REF].
Classes on the new Taft campus formally started on October 3, 1921, while the building was completed on December 15, 1924.