Making her professional boxing debut on April 18, 2000, in Phoenix, Elena "Baby Doll" Reid defeated Jo Ellen Caldwell by a four-round decision.
On September 11, 2004 at DM Arena in Karlsruhe, Germany, Elena Reid fought her first title fight when she took on local favorite and German media darling Regina Halmich, for Halmich's WIBF Flyweight Title.