Mary Leiter and George Curzon were married on 22 April 1895 at St. John's Episcopal Church in Washington, D.C., by Bishop Talbot, assisted by the Rev. Dr. Mackay Smith, the pastor of the church.
She played an important role in the reelection of her husband to Parliament that autumn and many thought that his success was due more to the winning smiles and irresistible charm of his wife than to his own speeches.