Cannadine was appointed to the professorial chair of history at Columbia University in 1988, returning to Britain ten years later as director of the Institute of Historical Research at the University of London and, subsequently, as Queen Elizabeth the Queen Mother Professor of British History.
Cannadine has held many other visitorial appointments: at the Institute for Advanced Study at Princeton (twice), at Birkbeck College, London, at the Whitney Humanities Center, Yale, at ANU Canberra, at the NHC North Carolina, at the Huntington Library and at New York University Stern School of Business.