After the Norman invasion, William the Conqueror rewarded William de Warenne, 1st Earl of Surrey, with the Rape of Lewes, a swathe of land along the River Ouse from the coast to the Surrey boundary.
The town was the site of the Battle of Lewes between the forces of Henry III and Simon de Montfort in the Second Barons' War in 1264, at the end of which de Montfort's forces were victorious.