Mayfield was home to professional baseball's minor league Class D Kentucky-Illinois-Tennessee League (or KITTY League) Mayfield Pantsmakers (1922-24), Mayfield Clothiers (1936-38, 1946-55), and Mayfield Browns (1939-41) [REF].
The Clothiers were the first team to integrate the Kitty League when they employed African-American and Mayfield native Mickey Stubblefield as a pitcher during the 1952 season.