This train runs via Bangarpet, Kuppam, Jolarpettai, Vaniyambadi, Katpadi, Chittoor, Tirupati, Gudur, Nellore, Vijayawada, Gudiwada, , Nidadavole and Rajahmundry to Kakinada.
The Seshadri Express runs between Kakinada and the software capital of India, Bangalore, via Tirupati.