Selected for Ireland's inaugural One Day International against England at Stormont despite a series of low scores in the preceding C&G Trophy matches, Botha vindicated the selectors' judgement by top-scoring with 52 against a first-rate attack including Steve Harmison, Liam Plunkett and Sajid Mahmood.
In August 2006, Botha was named in the 14 man squad which will represent Ireland at both the World Cricket League in Kenya and the Caribbean-hosted World Cup later the same year.