In 2005 Tiger Airways started thrice-weekly flights between Hanoi and Singapore after launching direct flights between Hồ Chí Minh City and Singapore becoming the first budget airline to operate in Vietnam.
The second runway (1B - 11R/29L) opened in 2006 and the following year the airport hosted an Airbus A380 for the first time, although no scheduled A380 services are operated from the airport.