Cook had graduated from CalArts and conceived the show's premise after seeing two stray dogs roaming around his apartment complex.
2 Stupid Dogs eventually helped launch the careers of creators Genndy Tartakovsky (Dexter's Laboratory, Samurai Jack, Star Wars: Clone Wars and Sym-Bionic Titan), Craig McCracken (The Powerpuff Girls, Foster's Home for Imaginary Friends and Wander Over Yonder), Butch Hartman (The Fairly OddParents, Danny Phantom and T.U.F.F.