Emetogenicity: HIGH The following protocol is recommended by EVIQ: Aprepitant 125 mg day 1 then 80 mg day 2 and 3 AND Dexamethasone 12 mg day 1 then 8 mg daily up to 4 days post chemotherapy AND 5HT3 antagonist day 1.
Ensure that patients have sufficient antiemetics for breakthrough emesis: Metoclopramide 10 mg to 20 mg every 4 to 6 hours when necessary OR Prochlorperazine 10 mg PO or 12.5 mg IV every 4 to 6 hours when necessary.