Elsene/Ixelles is located in the south of Brussels and is divided into two parts by Louisalaan / Avenue Louise, which is part of the City of Brussels municipality.
The larger east part of the municipality includes the campuses of Brussels' two leading universities, the Francophone Université Libre de Bruxelles and the Dutch-speaking Vrije Universiteit Brussel, along with the Place Eugène Flagey/Flageyplein.