There are conflicting reports on the extent of deficiency in the U.S. One review indicates approximately 25% of adolescents, adults, and people over 65, do not meet the Recommended Dietary Allowance for copper [REF].
Acquired copper deficiency has recently been implicated in adult-onset progressive myeloneuropathy[REF] and in the development of severe blood disorders including myelodysplastic syndrome [REF].