Ancient Cisamus became a Christian bishopric, a suffragan of the metropolitan see of Gortyna, the capital of the Roman province of Crete.
Only two of its first-millennium bishops are named in extant contemporary documents: Theopemptus (according to 18th-century Lequien), Nicetas (according to 20th-century Janin) at the Trullan Council in 692, and Leo at the Second Council of Nicaea in 787 [REF].