Luhonono lies at the far eastern end of the Caprivi Strip, about 1 km south of the river Zambezi and about 65 km east of Katima Mulilo, which is today the region's administrative seat, a role once performed by Schuckmannsburg when Namibia was a German colony.
Owing to the way that Africa was carved up by the European powers in the 19th century in their so-called "Scramble for Africa", Luhonono lies right near several other countries, Zambia just to the north, Botswana about 30 km to the south and Zimbabwe about 50 km to the east.