On 14 July 2008, it was reported that Lyon had reached an agreement with Sevilla FC for the transfer of Squillaci for a transfer fee of €6.25 million plus €0.5M bonus [REF].
Due to his poor performances in his first season and the arrival of German international, Per Mertesacker in the summer of 2011, Squillaci fell down the pecking order at the club ahead of the 2011-12 season.