Envisaged by the late His Highness Sir Sayajirao Gaekwad III as a seat of learning, Medical College Baroda and Shri Sayajirao General (SSG) Hospital was founded in the city of Vadodara by the late Maharaja of Baroda, Major General Sir Pratapsingh Gaekwad January 1946.
For initial development, the institute was entrusted to the late D. A. N. Deodars - the first Dean and Medical Superintendent of S. S. G. Hospital.