Calheta de Nesquim is situated in the southwest coast of Pico, 18 kilometers from the municipal seat of Lajes do Pico, and connected to the parishes of Piedade (Lajes do Pico) and Ribeiras by the Regional E.R.1-1ª motorway.
Its heart is the town of the same name, and is covered in dense vegetation in the interior and rugged cliffs to along the coast, extending to smaller hamlets: Foros, Cruz da Calheta, Jogo da Bola, Fetais, Canada da Saúde, Canadas, Terreiro and Feteira.