In addition to Nevado del Ruiz, seven other volcanoes are located in the area: Nevado del Tolima, Santa Isabel, Nevado del Quindío, Páramo de Santa Rosa, Cerro Bravo, Cerro Machín and Nevado El Cisne.
The park is located in the departments of Caldas, Quindío, Risaralda, Tolima and divided in the municipalities Villamaría, Santa Rosa de Cabal, Pereira, Salento and Ibagué.