NIIs have also been demonstrated to alter the distribution of the intranuclear structures, such as [[promyelocytic leukemia protein]] (PML) nuclear bodies.
Filementous, [[ATN1|atrophin-1]] positive, inclusions are also observed exclusively in the [[cytoplasm]] of the [[dentate nucleus]], which are extremely similar to the inclusions observed in the [[motor neuron]]s in [[amyotrophic lateral sclerosis]] [REF].