In November 2014, Marvel revealed that main cast members Clark Gregg, Ming-Na Wen, Brett Dalton, Chloe Bennet, Iain De Caestecker, Elizabeth Henstridge, and Nick Blood would star as Phil Coulson, Melinda May, Grant Ward, Skye, Leo Fitz, Jemma Simmons, and Lance Hunter, respectively [REF].
On portraying Agent 33, Ming-Na Wen stated that "It's sort of a sad character for me to portray because she's so opposite from May.