On December 6, 1963, Cardinal Spellman High School, along with several other secondary schools in the Archdiocese of Boston, was incorporated as a member of the Archdiocesan Central High Schools, Inc.
Cardinal Spellman High School was incorporated in January 2004 after the Board of Trustees of the Archdiocesan Central High Schools, Inc., determined that each of its schools would be best served by becoming an independent public juridic institution governed by its own Board of Trustees.