The song has been used in a number of films, including An American Werewolf in London, My Fellow Americans, Twilight Zone: The Movie, Blade, Sweet Home Alabama, My Girl, Man of the House, Mr. Woodcock, and The Big Chill.
It has also appeared in many television programs, including Supernatural, Cold Case, Northern Exposure, The Following, The Walking Dead, Teen Wolf, and Alvin and the Chipmunks, in which it is performed by the title characters.