Interference tends to be more troublesome with older radio technologies such as analogue amplitude modulation, which have no way of distinguishing unwanted in-band signals from the intended signal, and the omnidirectional antennas used with broadcast systems.
The most extreme example of digital spread-spectrum signalling to date is ultra-wideband (UWB), which proposes the use of large sections of the radio spectrum at low amplitudes to transmit high-bandwidth digital data.