Exosystem (the external settings that indirectly affect but do not include the patient): When his family also understands his medical condition and drug therapy, they can provide encouragement and support which will prompt a sense of closeness experienced by the patient.
Chronosystem (the time-space dimension over the patient's course of life): As the patient gains more moral support in time from others with similar experiences, he can better adapt to life and may be motivated to improve his lifestyle and keep healthy.