Part of the municipal territory is covered by the , a system of lakes created by mining and (gravel) quarrying that stretches across the Hessian-Bavarian border and is named after the town Kahl am Main.
Großkrotzenburg borders on (from the north, clockwise) Hanau, Kahl am Main (in (Aschaffenburg district), and Hainburg (in Offenbach district).