Her father was George I, Duke of Saxe-Meiningen; and her mother was Luise Eleonore, daughter of Prince Christian of Hohenlohe-Langenburg.
On 22 June 1850 she was one of the godparents of Prince Arthur, Duke of Connaught and Strathearn, third son of Queen Victoria and Prince Albert; however, because was unable to be physically present, she was represented by the Duchess of Kent, mother of the Queen.