DEC's 32-bit successor to the PDP-11, the VAX (for "Virtual Address eXtension") overcame the 16-bit limitation, but was initially a superminicomputer aimed at the high-end time-sharing market.
By the late 1990s, not only DEC but most of the New England computer industry which had been built around minicomputers similar to the PDP-11 collapsed in the face of microcomputer-based workstations and servers.