Matjan Berbisik was directed by Tan Tjoei Hock and produced by The Teng Chun for Action Film, a subsidiary of Java Industrial Film (JIF).
The film starred Mohamad Mochtar and Hadidjah, who had first acted together in The's Alang-Alang (Grass; 1939) and were promoted as a celebrity couple in competition with Raden Mochtar and Roekiah of Tan's Film.