Dimitrios Papadopoulos made his debut in the Greek National Team on 20 November 2002 against Republic of Ireland and he was included in the squad of Euro 2004 that went on to win the tournament.
On 29 August 2013, the coach of the Greek National team, Fernando Santos announced the return of Dimitrios Papadopoulos after six years [REF] for the match against Liechtenstein in Vaduz at the Rheinpark Stadion stadium for the 2014 FIFA World Cup qualification.