Irish physician Robert James Graves first describes symptoms of Graves' disease [REF].
French physician Pierre Charles Alexandre Louis publishes his book Recherches sur les effets de la saignée dans quelques maladies inflammatoires et sur l'action de l'émétique et des vésicatoires dans la pneumonie in Paris, in which he analyzes case studies to demonstrate that bloodletting is largely ineffective as a treatment [REF].