The show focuses on the employees of the fictional Sunshine Cab Company, (the building seen in the show once stood where 534 Hudson Street in Manhattan stands today.)
Despite the zany humor of the show, Taxi often tackled such dramatic issues as racism, drug addiction, single parenthood, blindness, obesity, animal abuse, bisexuality, teenage runaways, divorce, nuclear war, sexual harassment, premenstrual mood disorders, gambling addiction, and the loss of a loved one.