The 1965 episode of The Flintstones titled "Samantha" (1965), features Dick York and Elizabeth Montgomery as Darrin and Samantha Stephens, who have just moved into the neighborhood.
An animated cartoon made in 1972 by Hanna-Barbera Productions for The ABC Saturday Superstar Movie, this featured teenage versions of Tabitha and Adam visiting their aunt and her family who travel with a circus.