In 1976, Marvel and DC Comics collaborated on Superman vs. the Amazing Spider-Man, and seeking to replicate that success the two companies again teamed the characters in Superman and Spider-Man in 1981.
After Byrne's departure Doctor Doom continued to be a major villain in Fantastic Four, and as the 1980s continued Doom appeared in other comics such as Punisher, The Spectacular Spider-Man, and Excalibur.