Dextromethorphan's hallucinogenic and dissociative effects can be attributed largely to dextrorphan (DXO), a metabolite produced when dextromethorphan is metabolized by the body.
Dextromethorphan's euphoric effects have sometimes been attributed to an increase in dopamine levels, since such an increase generally correlates with pleasurable responses to drug, as is observed with some clinical antidepressants, as well as some recreational drugs.