Before railroads and highways were developed, the Rhône was an important inland trade and transportation route, connecting the cities of Arles, Avignon, Valence, Vienne and Lyon to the Mediterranean ports of Fos-sur-Mer, Marseille and Sète.
The Rhône is infamous for its strong current when the river carries large quantities of water: current speeds up to 10 kilometres per hour (6 mph) are sometimes reached, particularly in the stretch below the last lock at Valabrègues and in some of the diversion canals.