The company was founded in 1903 in Los Angeles as Standard Homeopathic Pharmacy.
In 2013, the FDA conducted a review of Hyland's labeling and marketing information which revealed numerous products misbranded in violation of sections 503 and 301 of the Federal Food, Drug, and Cosmetic Act (FD&C Act) [21 U.S.C. §§ 353 and 331].