The college has its own administration buildings, lecture rooms and other offices located at Pleinlaan 5 in the Brussels borough of Ixelles, adjacent to the main Etterbeek campus of the Vrije Universiteit Brussel.
On the Pleinlaan campus, Vesalius College has its administrative offices, classrooms, a conference room, computer facilities as well as the Student Lounge and the English and Math Workspace.