The railway is often associated with the main transcontinental Russian line that connects hundreds of large and small cities of the European and Asian parts of Russia.
The main route of the Trans-Siberian Railway begins in Moscow at Yaroslavsky Vokzal, runs through Yaroslavl, Chelyabinsk, Omsk, Novosibirsk, Irkutsk, Krasnoyarsk, Ulan-Ude, Chita, and Khabarovsk to Vladivostok via southern Siberia.