In 2002, ideas were floated to re-merge Cardiff with the University of Wales College of Medicine (UWCM) following the publication of the Welsh Assembly Government's review of higher education in Wales.
In 2005, The Wales College of Medicine, which is part of the University, launched the North Wales Clinical School in Wrexham in collaboration with the North East Wales Institute of Higher Education in Wrexham and the University of Wales, Bangor and with the National Health Service in Wales.