Radionuclides used in PET scanning are typically isotopes with short half-lives [REF] such as carbon-11 (~20 min), nitrogen-13 (~10 min), oxygen-15 (~2 min), fluorine-18 (~110 min), gallium-68 (~67 min), zirconium-89 (~78.41 hours), or rubidium-82(~1.27
Due to the short half-lives of most positron-emitting radioisotopes, the radiotracers have traditionally been produced using a cyclotron in close proximity to the PET imaging facility.