Sembrano is a co-anchor on TV Patrol, a newscaster on the DZMM radio station programs like Radyo Patrol Alas Dose, Gising Pilipinas with Nelson Lubao and currently anchoring Radyo Patrol Alas Kuwatro with Alex Santos when she replaced Jasmin Romero.
On August 3, 2015, she was named permanent co-anchor of the weekday editions of the said flagship national evening newscast, succeeding Korina Sanchez who left due to Mar Roxas's impending presidential campaign, according to news website medianewser.com.