In the past, alcohol was believed to be a non-specific pharmacological agent affecting many neurotransmitter systems in the brain [REF].
Among the neurotransmitter systems with enhanced functions are: GABAA,[REF] 5-HT3 receptor agonism[REF] (responsible for GABAergic (GABAA receptor PAM), glycinergic, and cholinergic effects), nicotinic acetylcholine receptors [REF].