Recently, a ground breaking discovery was made, which showed for the first time that choline kinase α can act as a protein chaperone (Asim et al., 2016 ;JNCI "Choline kinase alpha is an androgen receptor chaperone and prostate cancer therapeutic target").
In vivo studies carried out using CKα-1 and CKβ isoforms suggest that each isoform might be involved in different biochemical pathways.