From the product mixtures, the low-substituted phenol derivatives can be isolated by distillation.
Phenol reacts at temperatures of 50-60 ° C. in the presence of acidic catalysts such as, for example, sulfuric acid or aluminum chloride and an excess of gaseous isobutene in yields of up to 90% to give 2,4,6-tri-tert-butylphenol [REF].