The fundamental idea of abiogenesis, according to the iron-sulfur world hypothesis can be simplified in the following brief characterization: Pressurize and heat a water flow with dissolved volcanic gases (e.g.
Reaction of carbon monoxide (CO), hydrogen sulfide (H2S) and methanethiol CH3SH in the presence of nickel sulfide and iron sulfide generates the methyl thioester of acetic acid [CH3-CO-SCH3] and presumably thioacetic acid (CH3-CO-SH) as the simplest activated acetic acid analogues of acetyl-CoA.