Santhosh Dhayanidhi began his career in film music by working as a keyboard programmer for A. R. Rahman, and worked with the director for two years from the production of the albums to Kadal (2013) and Lingaa (2014).
Santhosh made his debut as a composer with the comedy film Inimey Ippadithan (2016) after being recommended to the producer by the lead actor Santhanam.