The series' theme song was "Where Love Spends the Night", arranged and composed by George Aliceson Tipton (the regular theme and score composer for Witt/Thomas/Harris shows) and performed in a duet by Paul Williams and Crystal Gayle [REF].
Two different cuts of the opening vocal theme were used during It Takes Twos single-season run; the second version had certain lines that were sung by Paul Williams in the first version be sung by Crystal Gayle instead.