The blossoming of renaissance humanism was made very much possible due to the universality of the institutions of Catholic Church and represented by personalities such as Pope Pius II, Nicolaus Copernicus, Leon Battista Alberti, Desiderius Erasmus, sir Thomas More, Bartolomé de Las Casas, Leonardo da Vinci and Teresa of Ávila.
In modern history, the Reformation and rise of modernity in the early 16th century entailed a change in the Corpus Christianum.