De Valette has been referred to as one who never broke his vows, but it has been claimed that he had a mistress while in Rhodes called Catherine nicknamed Greque (Greek), and that he had an illegitimate son from her who was called Barthélemy de Valette.
Claims have also been put forth that de Valette had at least another daughter, Isabella Guasconi, after a presumed affair with the wife of a Rhodiot nobleman of Florentine descent.