The authors proposed a theoretical model (hereby named the 'MRK model' after the main proponents- Gita Mahmoudabadi, Govindan Rangarajan, and Prakash Kulkarni) which envisaged that because IDPs have multiple conformational states and rapid conformational dynamics, they are prone to engage in 'promiscuous' interactions.
Together, these observations tend to suggest that contrary to the prevailing wisdom that phenotype specification is highly deterministic, stochasticity may be a confounding factor in specifying cell fate.