Karl married on 9 June 1817 in Vienna to Countess Marie Berchtold, Baroness of Ungarschitz (1794-1878), elder daughter of Count Anton Berchtold, and his wife, Marie Anna Franziska Huszár de Szent-Baráth.
Bohuslav, Count Chotek of Chotkow and Wognin (3 July 1829 - 11 October 1896), married in 1859 to Countess Wilhelmine Kinsky of Wchinitz and Tettau; had issue.