The road runs north-west from Marble Arch to Edgware on the outskirts of London.
As it passes through the various neighbourhoods, the road name changes several times, becoming Maida Vale, Kilburn High Road and Shoot-Up Hill (in Kilburn), and Cricklewood Broadway (in Cricklewood), before becoming Edgware Road once again with intermittent stretches as West Hendon Broadway, and the Hyde.