In September 1830, in declining health at age 76, Murdoch's partnership with Boulton & Watt which began in 1810 came to an end, at which point he was receiving £1,000 per year.
His life and works are commemorated by the Moonstones; a statue of him, Boulton and Watt, by William Bloye; and Murdock Road, all in Birmingham.