Jeffrey Mark, a librarian with the New York Public Library and the first to write about Drexel 5611, observed that the manuscript contains three works by French composers, indicating that it was compiled during the reign of Charles II of England.
In her discussion of the manuscript, Candace Bailey noted that Gerald Hendrie (editor of an edition of Orlando Gibbons's keyboard music) observed that Gibbons's composition "The Queen's Command" exists both in Drexel 5611 and in British Library manuscript Add.