The composer Paul Hindemith attended a music school in Mühlheim during five years of his childhood.
Among honorary citizens are Bruno Polga, former mayor of the French partner town of St.-Priest, retired district chief (Landrat) Walter Schmitt (SPD), retired first councillor Horst Lehr (SPD), Reinhold Latzke (SPD) and Irmgard Sondergeld (CDU).