Helena was largely responsible for the revival of Greek influence in Cyprus due to the numerous members of the Byzantine court who arrived in her wake and were given positions at the Lusignan court.
In 1457, she poisoned her son-in-law, Infante John of Portugal,[REF] who had given his support to the Catholic party, thus incurring her wrath and enmity;[REF] also she wished for her daughter to marry Louis of Savoy.