"I'm on Fire" was performed only sporadically at the start of the Born in the U.S.A. Tour, but a couple of months later, it settled into a regular place in the middle of the second set.
Between 1999 and 2008, the song was only performed on eight occasions with the E Street Band: once on the Reunion Tour (June 17, 1999, Bremen), once on The Rising Tour (April 18, 2003, Ottawa) and six times on the Magic Tour.