On June 20, 1863, Cabell County, Virginia, was one of the 50 counties separated from Virginia at the height of the American Civil War to form the State of West Virginia, and the college fell within the new state.
With the exception of the Old Main building, expansion of the facilities and the college itself did not begin until 1907, when the West Virginia Board of Regents changed the title of the presiding officer from "principal" to "president" and allowed the creation of new college-level departments [REF].