La Consolación College is along Mendiola Street, and occupies a trapezoidal, 2.8 hectare lot enclosed by Arlegui, San Rafael, C.A. Aguila and Mendiola streets.
With the completion of the LRT-2 with stations at Recto and Legarda, La Consolacion College Manila is only minutes away from areas up north like Pasig, Marikina, and Quezon City.