Early on, those volunteers saw a need for a permanent hospital that would "care for sick, injured and crippled children from birth to 16 years of age" and which would be supported mainly by volunteer contributions.
In 1909, Children's Colorado converted a former residence at 2221 Downing Street in Denver into a "well equipped institution with a capacity of 30 beds," admitting its first patients on Feb. 17, 1910.