To clarify what Xplico does we can imagine to have the raw data (Ethernet or PPP) of a web navigation (HTTP protocol), in this case Xplico is able to extract and reconstruct all the Web pages and contents (images, files, cookies, and so on).
Among the protocols that Xplico identifies and reconstructs there are VoIP, MSN, IRC, HTTP, IMAP, POP, SMTP and FTP.