In Spider-Man #18-23, Electro, Mysterio, Vulture, and Hobgoblin reunite in a bid to take revenge on Doctor Octopus.
Eventually Sandman and the second Mysterio (the original had committed suicide following his fight with Daredevil) form a new version of the Sinister Six, with Venom temporarily replacing Doc Ock with the other members consisting of Electro, the second Kraven the Hunter, and Vulture.