During the Third Macedonian War in 169 BC the Romans broke through Perseus of Macedon's defences here and later defeated him in the Battle of Pydna.
The most severe happened in 2003: an entire 11th grade class of 21 students from the village of Makrochori (Prefecture of Imathia) perished when a truck carrying plywood, coming from the opposite direction, hit their bus on its side [REF].