Françoise of Alençon, Duchess of Beaumont (1490- 14 September 1550), married firstly in 1505, François, Duke of Longueville; married secondly in 1513, Charles de Bourbon, Duke of Vendôme, by whom she had thirteen children.
Anne, Lady of La Guerche (30 October 1492- 18 October 1562), married in 1508, William IX Palaeologos, Marquis of Montferrat by whom she had three children.