From 1994 until 2003, as Bishop of Pittsburgh, Wuerl served as a member of the board of governors of the Pontifical North American College in Rome (Chairman, 1998-1999), representing the Pennsylvania-New Jersey Region (Region III) of the United States Conference of Catholic Bishops.
On October 24, 2011, Pope Benedict XVI named Wuerl the Relator-General (recording secretary) of the 2012 World Synod of Bishops meeting on the New Evangelization [REF].