Phosphoglucomutase effects a phosphoryl group shift by exchanging a phosphoryl group with the substrate [REF].
This formation of a glucose 1,6-bisphosphate intermediate is analogous to the interconversion of 2-phosphoglycerate and 3-phosphoglycerate catalyzed by phosphoglycerate mutase, in which 2,3-bisphosphoglycerate is generated as an intermediate [REF].