In early July 2005, Weinstein became one of the first members of Adam Curry's PodShow and was featured heavily in the program, which aired on Sirius Satellite Radio from 6-10 p.m. EST on weekdays before the company's ties with the radio network were controversially severed on May 1, 2007.
In early January 2008, with the threat of her expiring PodShow contract, Weinstein relaunched Yeast Radio as a live show, airing on her website from 10:00 CT on Fridays.