The AN2 region of the short arm of chromosome 11 (11p13) includes the PAX6 gene (named for its PAired boX status), whose gene product helps regulate a cascade of other genetic processes involved in the development of the eye (as well as other non-ocular structures) [REF].
Defects in the PAX6 gene cause aniridia-like ocular defects in mice (as well as Drosophila).