Discontinuation of baclofen can be associated with a withdrawal syndrome which resembles benzodiazepine withdrawal and alcohol withdrawal.
Reports of overdose indicate that baclofen may cause symptoms including vomiting, weakness, sedation, somnolence, respiratory depression, seizures, unusual pupil size, dizziness,[REF] headaches,[REF] itching, hypothermia, bradycardia, hypertension, hyporeflexia, coma, and death [REF].