Cleopatra reappears in A Necessary Fiction (2007), when Antony is forced by Octavian to relocate to Egypt, leaving Atia and new wife Octavia in Rome.
Years later in the next episode, Deus Impeditio Esuritori Nullus (No God Can Stop a Hungry Man) (2007), Antony and Cleopatra are in Egypt raising their own twins, Helios and Selene; she urges him to declare war on Rome to free himself once and for all from Octavian's tyranny.