Gliotransmitters have been shown to control synapse development and regulate synaptic function, and their release can lead to paracrine actions on astrocytes as well as the regulation of neurotransmission [REF].
Glial cells are important in hormonal and neuroendocrine function in the central nervous system and have an active role in sleep, cognition, synaptic function and plasticity, and promote remyelination and regeneration of injured nervous tissue [REF].