The first Ani-Men debuted in Daredevil #10 (October, 1965) and were created by Wally Wood (writer, co-artist) and Bob Powell (co-artist).
The second Ani-Men debuted in Daredevil #157 (March, 1979) and were created by Roger McKenzie (co-writer), Mary Jo Duffy (co-writer), Gene Colan (artist), and Klaus Janson (inker).