In 1926, he left the Savoy and opened his 'School of Syncopation' which specialised in teaching modern music techniques such as ragtime and stride piano.
In the 1930s Mayerl composed several works for the musical theatre including three connected with horse racing, Sporting Love, opening at the Gaiety Theatre, London in 1934, Twenty to One (Coliseum 1935), and Over She Goes (Saville 1936).