Isabella's brother Gauthier had left Greece sometime in the 1340s, and her eldest surviving son Sohier of Enghien apparently was resident lord of Argos and Nauplia from c. 1350.
Her main inheritance went, after some interludes, to the children of her third son John of Enghien: Peter I of Enghien, who died childless, and Mary of Enghien (1367-1446).