Lilí del Mónico 1948 began taking painting lessons in oil painting at Lausanne (Switzerland) with Professor David Burner and in Asuncion with Jaime Bestard .
At the beginning of the decade of 1950 she held her first solo exhibition in the Paraguayan American Cultural Center (CCPA) in 1952 and participated in the Women's Hall of Fine Arts at the Union Club, both institutions of the Paraguayan capital.