Sic1 is an inhibitor in which species of yeast used in winemaking and breadmaking?
Sic1 Sic1, a protein, is a stoichiometric inhibitor of Cdk1-Clb (B-type cyclins) complexes in the budding yeast "Saccharomyces cerevisiae". Because B-type cyclin-Cdk1 complexes are the drivers of S-phase initiation, Sic1 prevents premature S-phase entry. Multisite phosphorylation of Sic1 is thought to time Sic1 ubiquitination and destruction, and by extension, the timing of S-phase entry.
Ogataea methanolica Ogataea methanolica is a homothallic haploid organism that offers many of the advantages of a eukaryotic expression system such as protein processing and protein folding, while being as easy to manipulate as "E. coli" or "Saccharomyces cerevisiae". It is faster, easier, and less expensive to use than other eukaryotic expression systems such as baculovirus or mammalian tissue culture, and generally gives higher expression levels. As a yeast, it shares the advantages of molecular and genetic manipulations with Saccharomyces, and it has the added