What is the largest city in the South Hemisphere?
The city of São Paulo, capital of the São Paulo state in Brazil, is the largest city by population (12.33 million people according to the 2020 census).
Instruction: What is the largest city in the South Hemisphere?
Context: 
Response: The city of São Paulo, capital of the São Paulo state in Brazil, is the largest city by population (12.33 million people according to the 2020 census).