Does having a real cork, artificial cork, or a screw-top have any impact on the quality of a bottle of wine?
Generally, no. There is little evidence to suggest any one closure is more superior than another for most wines. It is more important to have an airtight seal on a bottle of wine so as to prevent introduction of air into the bottle which would cause oxidation of the wine inside.
Instruction: Does having a real cork, artificial cork, or a screw-top have any impact on the quality of a bottle of wine?
Context: 
Response: Generally, no. There is little evidence to suggest any one closure is more superior than another for most wines. It is more important to have an airtight seal on a bottle of wine so as to prevent introduction of air into the bottle which would cause oxidation of the wine inside.