(CNN) -- Rafael Nadal must get past big-serving home hope Andy Roddick to have a shot at his first title in 11 months at the Sony Ericsson Open in Miami. 

The Spanish fourth seed crushed No. 8 Jo-Wilfried Tsonga of France 6-3 6-2 on Wednesday night to move into the semifinals of the ATP Tour event, which has already seen top-ranked Roger Federer, Novak Djokovic and Andy Murray fall by the wayside. 

Sixth seed Roddick is hoping to repeat his 2004 victory, with the American in similarly dominant form as he dispatched Nadal's 33rd-seeded compatriot Nicolas Almagro 6-3 6-3. 

Nadal, twice a losing finalist in the southern American city, also reached the last four at Indian Wells two weeks ago on his return from a knee injury. 

"When you play against Andy, it always is a big challenge," he told the ATP Tour Web site. 

"His serve, and he's a very good competitor. He's a winner. Gonna be a very tough match, no? I think I have to play my best tennis to try to win." 

Roddick, who has not dropped a set so far, will take on a player who will return to No. 3 in the world rankings next week following defending champion Murray's second-round exit. 

He reached the final at Indian Wells before losing to Nadal's conqueror Ivan Ljubicic, and was also a semifinalist in Miami in 2008. 

"Sometimes when you're not playing well, everything feels a little bit forced. When you play a lot of matches and play a high level, it feels like everything kind of slows down a little bit," he told the ATP site. 
Who says that Roddick will be a big challenge?
Nadal, twice a losing finalist in the southern American city, also reached the last four at Indian Wells two weeks ago on his return from a knee injury. 

"When you play against Andy, it always is a big challenge," he told the ATP Tour Web site