What would be the best alternative to jQuery, excluding pure-JavaScript?
<p>There are alot of JavaScript frameworks out there. Even server-side solutions, like Node.js, V8, etc.</p>

<p>When <strong>jQuery</strong> is not available, which framework should an average Web Developer/Designer use for <em>DOM Manipulation</em> in that case?</p>

<p>Please exclude pure JavaScript-DOM functions/methods from that list.</p>
