Placement of 2,5-dimethoxy-4-iodoamphetamine (DOI) and 2,5-dimethoxy-4-chloroamphetamine (DOC) in Schedule I (DEA1156)
2024-01-08 2024-01-08 2024-01-08 2024-01-08 2024-01-08 2024-01-08 2024-01-08 2024-01-08 2024-01-08 2024-01-08
DEA-2023-0168-0042 DEA-2023-0168-0039 DEA-2023-0168-0046 DEA-2023-0168-0056 DEA-2023-0168-0101 DEA-2023-0168-0082 DEA-2023-0168-0074 DEA-2023-0168-0064 DEA-2023-0168-0072 DEA-2023-0168-0078
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https://api.regulations.gov/v4/comments/DEA-2023-0168-0042 https://api.regulations.gov/v4/comments/DEA-2023-0168-0039 https://api.regulations.gov/v4/comments/DEA-2023-0168-0046 https://api.regulations.gov/v4/comments/DEA-2023-0168-0056 https://api.regulations.gov/v4/comments/DEA-2023-0168-0101 https://api.regulations.gov/v4/comments/DEA-2023-0168-0082 https://api.regulations.gov/v4/comments/DEA-2023-0168-0074 https://api.regulations.gov/v4/comments/DEA-2023-0168-0064 https://api.regulations.gov/v4/comments/DEA-2023-0168-0072 https://api.regulations.gov/v4/comments/DEA-2023-0168-0078
Kim Anonymous Thomas Andrew Anonymous Anonymous Robert John Jonathan Anonymous
Erickson Anonymous Miles Luistro Anonymous Anonymous Cassady Rath Ross Anonymous
I do not support putting psychedelics in schedulenone classification. These drugs are powerfully healing for many people and need to be studied Placing these compounds under Schedule I severely limits the ability of dedicated researches to research both these compounds and the serotonin system of the brain in general.  Scheduling compounds with largely no street presence, being already covered under the analogue act when used for human consumption, is a grave mistake.  Placement of 2,5-dimethoxy-4-iodoamphetamine (DOI) and 2,5-dimethoxy-4-chloroamphetamine (DOC) in Schedule I is a criminal act; a continuation of chronic long-term governmental abuse on ALL communities and families. In a Nation where war is the main GNP, it is imperative for the government to provide damage control to those who serve and to the family members and relatives of those who have. Every individual in our communities are left to clean up and tolerate the what and how these persons returning present.  These psychological messes have ended up in our streets since Reagan deinstitutionalized them and then we later jailed them. SHOW OUR COUNTRY YOU CARE ABOUT THE PEOPLE IN IT These substances should not be schedule 1 The above proposition is unscientific and shortsighted proposition on absolutely every level of analysis.  I am a medicinal chemist and a pharmacology Ph.D. student currently working on anti-Parkinsons drug development.  One of the compounds I am investigating as an anti-Parkinsons medication is in the same class of drugs as these compounds.  DOI, as Im sure the DEA is well aware, is THE standard serotonin 2A radioligand and a critical tool in serotonin pharmacology and in neuroimaging research more broadly. The field of neuroscience and the field of medicine both would not be where they are without DOI. A quick Google Scholar search yields 2,500 papers with the search term 2,5-dimethoxy 4-iodo amphetamine. It could not be more clear that the DEA does not care at all about science, research, or the development of drugs that can help ease the disease burden and concomitant suffering of the human race. These two drugs have almost zero recreational users, partially because their durations are intolerably long, their potency is great, and more enjoyable recreation drugs that are more easily available already exist. I, and I believe the DEA secretly agrees, do not expect either DOC or DOI to become drugs of abuse on any scale that matters, now or in the future. This move, rather, seems explicitly designed to impair basic scientific research rather than prevent some perceived illicit drug threat. These drugs (as I am also sure the DEA is aware) are also already covered under the Federal Analogue Act as analogues of 2C-B/Mescaline/and DOM.  There are already illegal for human consumption. How much more is the DEA willing to set back medicine, neuroscience, pharmacology, psychiatry, mental health treatment, veterans treatment, and basic sanity?  As far as I can tell this is the DEA showing their true colors; a vestigial and reactive church to puritanical prohibitionism, operating with absolutely no basis in science, fact, or rational discourse, willing to throw away the lives of fellow Americans, and the lives of others around the world by hampering the advancement of the medical sciences, all for the delusion that drug prohibition keeps society healthy. The scientific community can and will fight this proposal, and we can and will win.   DOi and DOc pose NO public health threat, and furthermore are incredibly important chemicals in neuroscientific research. Recreational use of these drugs is incredibly rare, and the research value certainly outweighs the threat they pose. Listen to the researchers, listen to the people who came forward in June July and August. Im disgusted that my government continues to act in such a foolish manner. Everyone that is involved in this effort to criminalize research should be ashamed of themselves. We Americans no longer believe you make drugs illegal because you care about us or our well-being. I can legally buy most of the most dangerous neurotoxins in this country. If i did so, it would be legal and nobody would card unless i gave them to someone. You make molecules illegal when people WANT to take them, not because these molecules are dangerous. We never voted for the existence of the DEA, so please stop being tyrants and stop classifying molecules with your scheduling system  NO I dont approve of this These chemicals show the movement through the brain to track neurological pathways because they are slightly radioactive.  Chemists that are trying to unlock the secrets of the brain using these molecules and not a single reported death in 75 plus years since their creation has been found.  The United States public made a bunch of comments about this last year and is now brought up again is insulting to the people of this great nation.  A concerned citizen Despite what the DEA docket says, 2,5-dimethoxy-4-iodoamphetamine (DOI) and 2,5-dimethoxy-4-chloroamphetamine (DOC) are rarely drugs of abuse. The open sale of these novel psychoactive amphetamines is extremely rare, and the amount of overdose deaths from these agents in recent memory is zero. The main result of scheduling these novel psychoactives would be wasted time. Given the increased interest in medical research involving drugs with similar pharmacological method of action, such as 4-hydroxy-n,n-dimethyl-tryptamine (Psilocin), the chilling effect on scheduling these two drugs (and thus their structural analogs) would have on constructing novel medical drugs and reevaluating older substances previously only conceived of as recreational drugs for medical efficacy would be tremendous, and a massive setback to medical research in psychiatry and neurology.Since the previous motion in 2022 also failed, I imagine public opinion has not changed much. Thus, this is a waste at best and a disingenuous attempt to force something to happen at worst.