🧬 Alpha-1 antitrypsin deficiency leads to liver failure via protein misfolding–but why do some patients progress while others don’t? Protective variants (MTMR12 &amp; FAM134A) + novel G2 analogs for protein degradation may hold the key! 🏥🔬 #Autophagy #LiverDisease @WashUDPS
#Autophagy #LiverDisease