PAX7, Official Symbol PAX7provided by HGNC Official Full Name paired box 7provided by HGNC Primary source HGNC:HGNC:8621 See related Ensembl:ENSG00000009709 MIM:167410; AllianceGenome:HGNC:8621 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HUP1; RMS2; PAX7B; CMYP19; MYOSCO Summary This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all