MYL12B, Official Symbol MYL12Bprovided by HGNC Official Full Name myosin light chain 12Bprovided by HGNC Primary source HGNC:HGNC:29827 See related Ensembl:ENSG00000118680 MIM:609211; AllianceGenome:HGNC:29827 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MLC-B; MRLC2 Summary The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in colon (RPKM 243.9), lung (RPKM 208.5) and 25 other tissues See more Orthologs mouse all