TUBB4A, Official Symbol TUBB4Aprovided by HGNC Official Full Name tubulin beta 4A class IVaprovided by HGNC Primary source HGNC:HGNC:20774 See related Ensembl:ENSG00000104833 MIM:602662; AllianceGenome:HGNC:20774 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DYT4; TUBB4; beta-5 Summary This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Jan 2014] Expression Biased expression in brain (RPKM 224.5), adrenal (RPKM 54.5) and 1 other tissue See more Orthologs mouse all