HELLS, Official Symbol HELLSprovided by HGNC Official Full Name helicase, lymphoid specificprovided by HGNC Primary source HGNC:HGNC:4861 See related Ensembl:ENSG00000119969 MIM:603946; AllianceGenome:HGNC:4861 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LSH; ICF4; PASG; SALNR; SMARCA6; Nbla10143 Summary This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2014] Annotation information Note: The sequence defining GeneID 220513, which was based on XM_017508.4 and annotated on 12q13.12, currently corresponds to this locus. [08 Feb 2009] Expression Broad expression in testis (RPKM 2.1), bone marrow (RPKM 1.7) and 22 other tissues See more Orthologs mouse all