TRIM37, Official Symbol TRIM37provided by HGNC Official Full Name tripartite motif containing 37provided by HGNC Primary source HGNC:HGNC:7523 See related Ensembl:ENSG00000108395 MIM:605073; AllianceGenome:HGNC:7523 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MUL; POB1; TEF3 Summary This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. Mutations in this gene are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. TRIM37 localizes in peroxisomal membranes, and has been implicated in human peroxisomal biogenesis disorders. [provided by RefSeq, Jul 2020] Expression Broad expression in testis (RPKM 19.8), brain (RPKM 14.1) and 23 other tissues See more Orthologs mouse all