TAS1R1, Official Symbol TAS1R1provided by HGNC Official Full Name taste 1 receptor member 1provided by HGNC Primary source HGNC:HGNC:14448 See related Ensembl:ENSG00000173662 MIM:606225; AllianceGenome:HGNC:14448 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TR1; T1R1; GM148; GPR70 Summary The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Expression Biased expression in testis (RPKM 1.2), gall bladder (RPKM 0.1) and 7 other tissues See more Orthologs mouse all