IKBKE, Official Symbol IKBKEprovided by HGNC Official Full Name inhibitor of nuclear factor kappa B kinase subunit epsilonprovided by HGNC Primary source HGNC:HGNC:14552 See related Ensembl:ENSG00000263528 MIM:605048; AllianceGenome:HGNC:14552 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IKKE; IKKI; IKK-E; IKK-i Summary IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009] Expression Broad expression in lymph node (RPKM 9.0), appendix (RPKM 7.5) and 20 other tissues See more Orthologs mouse all