TTLL1, Official Symbol TTLL1provided by HGNC Official Full Name TTL family tubulin polyglutamylase complex subunit L1provided by HGNC Primary source HGNC:HGNC:1312 See related Ensembl:ENSG00000100271 MIM:608955; AllianceGenome:HGNC:1312 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TPGS3; C22orf7; HS323M22B Summary Predicted to enable tubulin binding activity and tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule cytoskeleton organization and protein polyglutamylation. Predicted to act upstream of or within several processes, including cerebellar Purkinje cell differentiation; mucociliary clearance; and regulation of blastocyst development. Predicted to be located in cytoplasm; extracellular region; and microtubule cytoskeleton. Predicted to be active in cilium. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 7.3), brain (RPKM 5.8) and 24 other tissues See more Orthologs mouse all