MS4A1, Official Symbol MS4A1provided by HGNC Official Full Name membrane spanning 4-domains A1provided by HGNC Primary source HGNC:HGNC:7315 See related Ensembl:ENSG00000156738 MIM:112210; AllianceGenome:HGNC:7315 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B1; S7; Bp35; CD20; FMC7; CVID5; LEU-16 Summary This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008] Expression Biased expression in lymph node (RPKM 206.7), spleen (RPKM 109.2) and 2 other tissues See more Orthologs mouse all