VCAM1, Official Symbol VCAM1provided by HGNC Official Full Name vascular cell adhesion molecule 1provided by HGNC Primary source HGNC:HGNC:12663 See related Ensembl:ENSG00000162692 MIM:192225; AllianceGenome:HGNC:12663 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD106; INCAM-100 Summary This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010] Expression Biased expression in spleen (RPKM 208.8), lymph node (RPKM 52.3) and 7 other tissues See more Orthologs mouse all