HECTD1, Official Symbol HECTD1provided by HGNC Official Full Name HECT domain E3 ubiquitin protein ligase 1provided by HGNC Primary source HGNC:HGNC:20157 See related Ensembl:ENSG00000092148 MIM:618649; AllianceGenome:HGNC:20157 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EULIR Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in anatomical structure development; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein K63-linked ubiquitination. Predicted to act upstream of or within several processes, including animal organ development; negative regulation of protein localization to plasma membrane; and protein autoubiquitination. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 22.9), testis (RPKM 20.1) and 25 other tissues See more Orthologs mouse all