RALBP1, Official Symbol RALBP1provided by HGNC Official Full Name ralA binding protein 1provided by HGNC Primary source HGNC:HGNC:9841 See related Ensembl:ENSG00000017797 MIM:605801; AllianceGenome:HGNC:9841 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIP1; RLIP1; RLIP76 Summary RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010] Expression Ubiquitous expression in kidney (RPKM 28.4), skin (RPKM 27.5) and 25 other tissues See more Orthologs mouse all