RCN2, Official Symbol RCN2provided by HGNC Official Full Name reticulocalbin 2provided by HGNC Primary source HGNC:HGNC:9935 See related Ensembl:ENSG00000117906 MIM:602584; AllianceGenome:HGNC:9935 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as E6BP; ERC55; ERC-55; TCBP49 Summary The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012] Expression Ubiquitous expression in testis (RPKM 51.1), brain (RPKM 32.7) and 24 other tissues See more Orthologs mouse all