OSBPL3, Official Symbol OSBPL3provided by HGNC Official Full Name oxysterol binding protein like 3provided by HGNC Primary source HGNC:HGNC:16370 See related Ensembl:ENSG00000070882 MIM:606732; AllianceGenome:HGNC:16370 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ORP3; ORP-3; OSBP3 Summary This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded protein is involved in the regulation of cell adhesion and organization of the actin cytoskeleton. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in lymph node (RPKM 4.4), urinary bladder (RPKM 4.1) and 23 other tissues See more Orthologs mouse all