PDZD2, Official Symbol PDZD2provided by HGNC Official Full Name PDZ domain containing 2provided by HGNC Primary source HGNC:HGNC:18486 See related Ensembl:ENSG00000133401 MIM:610697; AllianceGenome:HGNC:18486 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIPC; PIN1; PAPIN; PDZK3 Summary The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015] Expression Biased expression in fat (RPKM 15.3), ovary (RPKM 9.0) and 12 other tissues See more Orthologs mouse all