EIF4EBP3, Official Symbol EIF4EBP3provided by HGNC Official Full Name eukaryotic translation initiation factor 4E binding protein 3provided by HGNC Primary source HGNC:HGNC:3290 See related Ensembl:ENSG00000243056 MIM:603483; AllianceGenome:HGNC:3290 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 4EBP3; 4E-BP3 Summary This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Oct 2010] Expression Ubiquitous expression in adrenal (RPKM 14.1), kidney (RPKM 13.1) and 25 other tissues See more Orthologs mouse all