TPM2, Official Symbol TPM2provided by HGNC Official Full Name tropomyosin 2provided by HGNC Primary source HGNC:HGNC:12011 See related Ensembl:ENSG00000198467 MIM:190990; AllianceGenome:HGNC:12011 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DA1; DA2B; NEM4; TMSB; AMCD1; DA2B4; CMYP23; HEL-S-273 Summary This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] Expression Broad expression in prostate (RPKM 355.8), endometrium (RPKM 279.3) and 16 other tissues See more Orthologs mouse all