NCF1, Official Symbol NCF1provided by HGNC Official Full Name neutrophil cytosolic factor 1provided by HGNC Primary source HGNC:HGNC:7660 See related Ensembl:ENSG00000158517 MIM:608512; AllianceGenome:HGNC:7660 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CGD1; NCF1A; NOXO2; p47phox; SH3PXD1A Summary The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 86.3), spleen (RPKM 53.3) and 10 other tissues See more Orthologs mouse all