HMGCS1, Official Symbol HMGCS1provided by HGNC Official Full Name 3-hydroxy-3-methylglutaryl-CoA synthase 1provided by HGNC Primary source HGNC:HGNC:5007 See related Ensembl:ENSG00000112972 MIM:142940; AllianceGenome:HGNC:5007 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMGCS Summary Enables protein homodimerization activity. Predicted to be involved in acetyl-CoA metabolic process and farnesyl diphosphate biosynthetic process, mevalonate pathway. Predicted to be located in cytoplasm. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 48.5), liver (RPKM 37.3) and 23 other tissues See more Orthologs mouse all