EDEM2, Official Symbol EDEM2provided by HGNC Official Full Name ER degradation enhancing alpha-mannosidase like protein 2provided by HGNC Primary source HGNC:HGNC:15877 See related Ensembl:ENSG00000088298 MIM:610302; AllianceGenome:HGNC:15877 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C20orf31; C20orf49; bA4204.1 Summary In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in placenta (RPKM 13.1), lung (RPKM 12.7) and 25 other tissues See more Orthologs mouse all