AMZ2, Official Symbol AMZ2provided by HGNC Official Full Name archaelysin family metallopeptidase 2provided by HGNC Primary source HGNC:HGNC:28041 See related Ensembl:ENSG00000196704 MIM:615169; AllianceGenome:HGNC:28041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016] Expression Broad expression in testis (RPKM 44.9), brain (RPKM 18.1) and 25 other tissues See more Orthologs mouse all