DESI2, Official Symbol DESI2provided by HGNC Official Full Name desumoylating isopeptidase 2provided by HGNC Primary source HGNC:HGNC:24264 See related Ensembl:ENSG00000121644 MIM:614638; AllianceGenome:HGNC:24264 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DESI; DESI1; DeSI-2; PNAS-4; PPPDE1; CGI-146; FAM152A; C1orf121 Summary Enables Lys48-specific deubiquitinase activity; Lys63-specific deubiquitinase activity; and thiol-dependent deubiquitinase. Predicted to be involved in protein deubiquitination. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 26.2), thyroid (RPKM 11.1) and 24 other tissues See more Orthologs mouse all