POLR2I, Official Symbol POLR2Iprovided by HGNC Official Full Name RNA polymerase II subunit Iprovided by HGNC Primary source HGNC:HGNC:9196 See related Ensembl:ENSG00000105258 MIM:180662; AllianceGenome:HGNC:9196 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RPB9; hRPB14.5 Summary This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 23.3), brain (RPKM 15.2) and 25 other tissues See more Orthologs mouse all