DPEP1, Official Symbol DPEP1provided by HGNC Official Full Name dipeptidase 1provided by HGNC Primary source HGNC:HGNC:3002 See related Ensembl:ENSG00000015413 MIM:179780; AllianceGenome:HGNC:3002 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MDP; RDP; MBD1 Summary The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. [provided by RefSeq, Dec 2020] Expression Biased expression in small intestine (RPKM 104.6), kidney (RPKM 102.2) and 3 other tissues See more Orthologs mouse all