PANK4, Official Symbol PANK4provided by HGNC Official Full Name pantothenate kinase 4 (inactive)provided by HGNC Primary source HGNC:HGNC:19366 See related Ensembl:ENSG00000157881 MIM:606162; AllianceGenome:HGNC:19366 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CTRCT49 Summary This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in spleen (RPKM 4.0), heart (RPKM 3.4) and 25 other tissues See more Orthologs mouse all