MVD, Official Symbol MVDprovided by HGNC Official Full Name mevalonate diphosphate decarboxylaseprovided by HGNC Primary source HGNC:HGNC:7529 See related Ensembl:ENSG00000167508 MIM:603236; AllianceGenome:HGNC:7529 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MPD; MDDase; POROK7; FP17780 Summary The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 12.6), duodenum (RPKM 12.3) and 25 other tissues See more Orthologs mouse all