H2BC18, Official Symbol H2BC18provided by HGNC Official Full Name H2B clustered histone 18provided by HGNC Primary source HGNC:HGNC:24700 See related Ensembl:ENSG00000203814 AllianceGenome:HGNC:24700 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HIST2H2BF Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family and is found in a histone cluster on chromosome 1. [provided by RefSeq, Aug 2015] Expression Broad expression in prostate (RPKM 4.3), appendix (RPKM 1.9) and 23 other tissues See more Orthologs all