REG1B, Official Symbol REG1Bprovided by HGNC Official Full Name regenerating family member 1 betaprovided by HGNC Primary source HGNC:HGNC:9952 See related Ensembl:ENSG00000172023 MIM:167771; AllianceGenome:HGNC:9952 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as REGH; REGL; PSPS2; REGI-BETA Summary This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008] Expression Biased expression in duodenum (RPKM 280.8), small intestine (RPKM 149.9) and 2 other tissues See more Orthologs all