BDH1, Official Symbol BDH1provided by HGNC Official Full Name 3-hydroxybutyrate dehydrogenase 1provided by HGNC Primary source HGNC:HGNC:1027 See related Ensembl:ENSG00000161267 MIM:603063; AllianceGenome:HGNC:1027 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BDH; SDR9C1 Summary This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] Expression Broad expression in liver (RPKM 11.8), colon (RPKM 4.8) and 19 other tissues See more Orthologs mouse all