WNK3, Official Symbol WNK3provided by HGNC Official Full Name WNK lysine deficient protein kinase 3provided by HGNC Primary source HGNC:HGNC:14543 See related Ensembl:ENSG00000196632 MIM:300358; AllianceGenome:HGNC:14543 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRKWNK3 Summary This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Expression Biased expression in testis (RPKM 7.2), brain (RPKM 1.1) and 5 other tissues See more Orthologs mouse all