IAPP, Official Symbol IAPPprovided by HGNC Official Full Name islet amyloid polypeptideprovided by HGNC Primary source HGNC:HGNC:5329 See related Ensembl:ENSG00000121351 MIM:147940; AllianceGenome:HGNC:5329 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DAP; IAP Summary This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016] Expression Restricted expression toward pancreas (RPKM 16.6) See more Orthologs mouse all