PYCR2, Official Symbol PYCR2provided by HGNC Official Full Name pyrroline-5-carboxylate reductase 2provided by HGNC Primary source HGNC:HGNC:30262 See related Ensembl:ENSG00000143811 MIM:616406; AllianceGenome:HGNC:30262 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HLD10; P5CR2 Summary This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012] Expression Ubiquitous expression in adrenal (RPKM 27.1), spleen (RPKM 24.2) and 25 other tissues See more Orthologs mouse all