NMBR, Official Symbol NMBRprovided by HGNC Official Full Name neuromedin B receptorprovided by HGNC Primary source HGNC:HGNC:7843 See related Ensembl:ENSG00000135577 MIM:162341; AllianceGenome:HGNC:7843 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BB1; BB1R; BRS1; NMB-R Summary This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] Expression Low expression observed in reference dataset See more Orthologs mouse all