CELA2B, Official Symbol CELA2Bprovided by HGNC Official Full Name chymotrypsin like elastase 2Bprovided by HGNC Primary source HGNC:HGNC:29995 See related Ensembl:ENSG00000215704 MIM:609444; AllianceGenome:HGNC:29995 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ELA2B Summary Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2B is secreted from the pancreas as a zymogen. In other species, elastase 2B has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, Jul 2008] Expression Restricted expression toward pancreas (RPKM 4511.4) See more Orthologs all