CBR3, Official Symbol CBR3provided by HGNC Official Full Name carbonyl reductase 3provided by HGNC Primary source HGNC:HGNC:1549 See related Ensembl:ENSG00000159231 MIM:603608; AllianceGenome:HGNC:1549 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hCBR3; SDR21C2; HEL-S-25 Summary Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in esophagus (RPKM 6.1), skin (RPKM 5.7) and 22 other tissues See more Orthologs mouse all