PSD, Official Symbol PSDprovided by HGNC Official Full Name pleckstrin and Sec7 domain containingprovided by HGNC Primary source HGNC:HGNC:9507 See related Ensembl:ENSG00000059915 MIM:602327; AllianceGenome:HGNC:9507 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TYL; EFA6; PSD1; EFA6A Summary This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] Expression Biased expression in brain (RPKM 23.5), endometrium (RPKM 9.6) and 8 other tissues See more Orthologs mouse all