RNASEH2C, Official Symbol RNASEH2Cprovided by HGNC Official Full Name ribonuclease H2 subunit Cprovided by HGNC Primary source HGNC:HGNC:24116 See related Ensembl:ENSG00000172922 MIM:610330; AllianceGenome:HGNC:24116 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AGS3; AYP1 Summary This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 17.9), endometrium (RPKM 15.2) and 25 other tissues See more Orthologs mouse all