ELMO1, Official Symbol ELMO1provided by HGNC Official Full Name engulfment and cell motility 1provided by HGNC Primary source HGNC:HGNC:16286 See related Ensembl:ENSG00000155849 MIM:606420; AllianceGenome:HGNC:16286 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CED12; CED-12; ELMO-1 Summary This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Expression Broad expression in brain (RPKM 17.7), thyroid (RPKM 16.1) and 22 other tissues See more Orthologs mouse all