DENND4B, Official Symbol DENND4Bprovided by HGNC Official Full Name DENN domain containing 4Bprovided by HGNC Primary source HGNC:HGNC:29044 See related Ensembl:ENSG00000198837 MIM:619843; AllianceGenome:HGNC:29044 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIAA0476 Summary Enables guanyl-nucleotide exchange factor activity. Involved in regulation of Rab protein signal transduction. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in spleen (RPKM 20.1), lymph node (RPKM 17.2) and 25 other tissues See more Orthologs mouse all