HMGN3, Official Symbol HMGN3provided by HGNC Official Full Name high mobility group nucleosomal binding domain 3provided by HGNC Primary source HGNC:HGNC:12312 See related Ensembl:ENSG00000118418 MIM:604502; AllianceGenome:HGNC:12312 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIP7; PNAS-24; PNAS-25 Summary The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in heart (RPKM 45.8), adrenal (RPKM 40.5) and 25 other tissues See more Orthologs mouse all