TESK2, Official Symbol TESK2provided by HGNC Official Full Name testis associated actin remodelling kinase 2provided by HGNC Primary source HGNC:HGNC:11732 See related Ensembl:ENSG00000070759 MIM:604746; AllianceGenome:HGNC:11732 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Expression Broad expression in prostate (RPKM 8.8), testis (RPKM 6.1) and 24 other tissues See more Orthologs mouse all