PODXL, Official Symbol PODXLprovided by HGNC Official Full Name podocalyxin likeprovided by HGNC Primary source HGNC:HGNC:9171 See related Ensembl:ENSG00000128567 MIM:602632; AllianceGenome:HGNC:9171 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PC; PDX; PCLP; Gp200; gp135; PCLP-1; PODXL1 Summary This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 88.8), lung (RPKM 31.4) and 19 other tissues See more Orthologs mouse all