DIRAS3, Official Symbol DIRAS3provided by HGNC Official Full Name DIRAS family GTPase 3provided by HGNC Primary source HGNC:HGNC:687 See related Ensembl:ENSG00000162595 MIM:605193; AllianceGenome:HGNC:687 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHI; NOEY2 Summary This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015] Expression Biased expression in ovary (RPKM 20.7), adrenal (RPKM 6.9) and 11 other tissues See more Orthologs all