PPP2R5B, Official Symbol PPP2R5Bprovided by HGNC Official Full Name protein phosphatase 2 regulatory subunit B'betaprovided by HGNC Primary source HGNC:HGNC:9310 See related Ensembl:ENSG00000068971 MIM:601644; AllianceGenome:HGNC:9310 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B56B; PR61B; B56beta Summary The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 15.1), gall bladder (RPKM 6.6) and 25 other tissues See more Orthologs mouse all