TEX15, Official Symbol TEX15provided by HGNC Official Full Name testis expressed 15, meiosis and synapsis associatedprovided by HGNC Primary source HGNC:HGNC:11738 See related Ensembl:ENSG00000133863 MIM:605795; AllianceGenome:HGNC:11738 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT42; SPGF25 Summary This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene stage. Naturally occurring mutations in this gene are associated with nonobstructive azoospermia. [provided by RefSeq, Apr 2017] Expression Biased expression in testis (RPKM 7.9) and endometrium (RPKM 3.5) See more Orthologs mouse all