FEM1B, Official Symbol FEM1Bprovided by HGNC Official Full Name fem-1 homolog Bprovided by HGNC Primary source HGNC:HGNC:3649 See related Ensembl:ENSG00000169018 MIM:613539; AllianceGenome:HGNC:3649 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as F1AA; F1A-ALPHA; FEM1-beta Summary This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in brain (RPKM 18.1), endometrium (RPKM 14.9) and 25 other tissues See more Orthologs mouse all