IL13RA1, Official Symbol IL13RA1provided by HGNC Official Full Name interleukin 13 receptor subunit alpha 1provided by HGNC Primary source HGNC:HGNC:5974 See related Ensembl:ENSG00000131724 MIM:300119; AllianceGenome:HGNC:5974 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NR4; CT19; CD213A1; IL-13Ra Summary The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in colon (RPKM 22.2), liver (RPKM 22.1) and 25 other tissues See more Orthologs mouse all