RANBP17, Official Symbol RANBP17provided by HGNC Official Full Name RAN binding protein 17provided by HGNC Primary source HGNC:HGNC:14428 See related Ensembl:ENSG00000204764 MIM:606141; AllianceGenome:HGNC:14428 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002] Expression Broad expression in testis (RPKM 1.6), thyroid (RPKM 0.5) and 15 other tissues See more Orthologs mouse all