MPP3, Official Symbol MPP3provided by HGNC Official Full Name MAGUK p55 scaffold protein 3provided by HGNC Primary source HGNC:HGNC:7221 See related Ensembl:ENSG00000161647 MIM:601114; AllianceGenome:HGNC:7221 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DLG3 Summary This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008] Expression Broad expression in heart (RPKM 3.1), lung (RPKM 2.5) and 23 other tissues See more Orthologs mouse all