MAP4K3, Official Symbol MAP4K3provided by HGNC Official Full Name mitogen-activated protein kinase kinase kinase kinase 3provided by HGNC Primary source HGNC:HGNC:6865 See related Ensembl:ENSG00000011566 MIM:604921; AllianceGenome:HGNC:6865 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLK; MEKKK3; MEKKK 3; MAPKKKK3; RAB8IPL1 Summary This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] Expression Ubiquitous expression in thyroid (RPKM 14.7), testis (RPKM 13.3) and 25 other tissues See more Orthologs mouse all