HSF1, Official Symbol HSF1provided by HGNC Official Full Name heat shock transcription factor 1provided by HGNC Primary source HGNC:HGNC:5224 See related Ensembl:ENSG00000185122 MIM:140580; AllianceGenome:HGNC:5224 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSTF1 Summary The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90. [provided by RefSeq, Jul 2017] Expression Ubiquitous expression in testis (RPKM 49.6), heart (RPKM 24.2) and 25 other tissues See more Orthologs mouse all