NHLH1, Official Symbol NHLH1provided by HGNC Official Full Name nescient helix-loop-helix 1provided by HGNC Primary source HGNC:HGNC:7817 See related Ensembl:ENSG00000171786 MIM:162360; AllianceGenome:HGNC:7817 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEN1; NSCL; NSCL1; bHLHa35 Summary The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002] Expression Low expression observed in reference dataset See more Orthologs mouse all