XK, Official Symbol XKprovided by HGNC Official Full Name X-linked Kx blood group antigen, Kell and VPS13A binding proteinprovided by HGNC Primary source HGNC:HGNC:12811 See related Ensembl:ENSG00000047597 MIM:314850; AllianceGenome:HGNC:12811 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KX; NA; NAC; X1k; XKR1 Summary This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008] Expression Broad expression in colon (RPKM 3.9), small intestine (RPKM 3.0) and 18 other tissues See more Orthologs mouse all