ARL6IP1, Official Symbol ARL6IP1provided by HGNC Official Full Name ADP ribosylation factor like GTPase 6 interacting protein 1provided by HGNC Primary source HGNC:HGNC:697 See related Ensembl:ENSG00000170540 MIM:607669; AllianceGenome:HGNC:697 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIP1; ARMER; SPG61; ARL6IP Summary This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015] Expression Ubiquitous expression in brain (RPKM 151.5), adrenal (RPKM 96.4) and 25 other tissues See more Orthologs mouse all