MRPS28, Official Symbol MRPS28provided by HGNC Official Full Name mitochondrial ribosomal protein S28provided by HGNC Primary source HGNC:HGNC:14513 See related Ensembl:ENSG00000147586 MIM:611990; AllianceGenome:HGNC:14513 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRPS35; COXPD47; HSPC007; MRP-S28; MRP-S35 Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in adrenal (RPKM 38.5), heart (RPKM 29.2) and 25 other tissues See more Orthologs mouse all