CYP39A1, Official Symbol CYP39A1provided by HGNC Official Full Name cytochrome P450 family 39 subfamily A member 1provided by HGNC Primary source HGNC:HGNC:17449 See related Ensembl:ENSG00000146233 MIM:605994; AllianceGenome:HGNC:17449 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Broad expression in liver (RPKM 10.7), prostate (RPKM 4.4) and 14 other tissues See more Orthologs mouse all