BCO1, Official Symbol BCO1provided by HGNC Official Full Name beta-carotene oxygenase 1provided by HGNC Primary source HGNC:HGNC:13815 See related Ensembl:ENSG00000135697 MIM:605748; AllianceGenome:HGNC:13815 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCO; BCDO; BCMO; BCDO1; BCMO1 Summary Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules. [provided by RefSeq, Jul 2008] Expression Biased expression in small intestine (RPKM 7.4), duodenum (RPKM 3.9) and 4 other tissues See more Orthologs mouse all