BICD1, Official Symbol BICD1provided by HGNC Official Full Name BICD cargo adaptor 1provided by HGNC Primary source HGNC:HGNC:1049 See related Ensembl:ENSG00000151746 MIM:602204; AllianceGenome:HGNC:1049 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BICD; bic-D 1 Summary This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017] Expression Broad expression in ovary (RPKM 4.3), brain (RPKM 3.8) and 20 other tissues See more Orthologs mouse all