ANXA4, Official Symbol ANXA4provided by HGNC Official Full Name annexin A4provided by HGNC Primary source HGNC:HGNC:542 See related Ensembl:ENSG00000196975 MIM:106491; AllianceGenome:HGNC:542 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANX4; P32.5; PIG28; PP4-X; ZAP36; PAP-II; HEL-S-274 Summary Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2016] Expression Broad expression in gall bladder (RPKM 187.6), duodenum (RPKM 64.1) and 17 other tissues See more Orthologs mouse all