SF3B6, Official Symbol SF3B6provided by HGNC Official Full Name splicing factor 3b subunit 6provided by HGNC Primary source HGNC:HGNC:30096 See related Ensembl:ENSG00000115128 MIM:607835; AllianceGenome:HGNC:30096 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P14; Ht006; SAP14; SAP14a; SF3B14; CGI-110; HSPC175; SF3B14a Summary This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 53.9), colon (RPKM 39.5) and 25 other tissues See more Orthologs mouse all