HOXB9, Official Symbol HOXB9provided by HGNC Official Full Name homeobox B9provided by HGNC Primary source HGNC:HGNC:5120 See related Ensembl:ENSG00000170689 MIM:142964; AllianceGenome:HGNC:5120 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HOX2E; HOX-2.5 Summary This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 12.6), kidney (RPKM 7.0) and 3 other tissues See more Orthologs mouse all