CLPX, Official Symbol CLPXprovided by HGNC Official Full Name caseinolytic mitochondrial matrix peptidase chaperone subunit Xprovided by HGNC Primary source HGNC:HGNC:2088 See related Ensembl:ENSG00000166855 MIM:615611; AllianceGenome:HGNC:2088 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPP2 Summary The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015] Expression Ubiquitous expression in liver (RPKM 13.6), testis (RPKM 11.0) and 25 other tissues See more Orthologs mouse all