ARPC1A, Official Symbol ARPC1Aprovided by HGNC Official Full Name actin related protein 2/3 complex subunit 1Aprovided by HGNC Primary source HGNC:HGNC:703 See related Ensembl:ENSG00000241685 MIM:604220; AllianceGenome:HGNC:703 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Arc40; SOP2L; HEL-68; SOP2Hs; HEL-S-307 Summary This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] Expression Ubiquitous expression in thyroid (RPKM 48.9), stomach (RPKM 46.5) and 25 other tissues See more Orthologs mouse all