ADRA1D, Official Symbol ADRA1Dprovided by HGNC Official Full Name adrenoceptor alpha 1Dprovided by HGNC Primary source HGNC:HGNC:280 See related Ensembl:ENSG00000171873 MIM:104219; AllianceGenome:HGNC:280 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DAR; ADRA1; ADRA1A; ADRA1R; ALPHA1; dJ779E11.2 Summary Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008] Expression Biased expression in prostate (RPKM 2.3), spleen (RPKM 0.8) and 10 other tissues See more Orthologs mouse all