TGFBI, Official Symbol TGFBIprovided by HGNC Official Full Name transforming growth factor beta inducedprovided by HGNC Primary source HGNC:HGNC:11771 See related Ensembl:ENSG00000120708 MIM:601692; AllianceGenome:HGNC:11771 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1 Summary This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008] Expression Broad expression in placenta (RPKM 227.8), skin (RPKM 133.2) and 19 other tissues See more Orthologs mouse all