BLTP2, Official Symbol BLTP2provided by HGNC Official Full Name bridge-like lipid transfer protein family member 2provided by HGNC Primary source HGNC:HGNC:28960 See related Ensembl:ENSG00000007202 MIM:610664; AllianceGenome:HGNC:28960 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Hob; BCOX; BCOX1; CT101; FMP27; KIAA0100 Summary This gene was initially characterized in human as having high expression levels in breast carcinomas and breast cancer cell lines. This gene also has increased expression in prostrate cancer cells relative to normal prostrate tissues. Expression of this gene is negatively regulated by direct binding of the microRNA miR-195 to its 3' UTR. miR-195 has been shown to modulate the invasiveness of prostrate cancer cells and xenograft metastases by downgrading expression of this gene. In mouse, the protein encoded by this gene was identified as an antigen on acute monocytic leukemia cells. In human, alternative splicing results in multiple transcript variants encoding distinct isoforms; some of these isoforms are predicted to contain an RNA pol II promoter FMP27 protein domain and a Golgi-body-localization APT1 domain. [provided by RefSeq, Apr 2017] Expression Ubiquitous expression in kidney (RPKM 27.5), thyroid (RPKM 25.9) and 25 other tissues See more Orthologs mouse all