CUL2, Official Symbol CUL2provided by HGNC Official Full Name cullin 2provided by HGNC Primary source HGNC:HGNC:2552 See related Ensembl:ENSG00000108094 MIM:603135; AllianceGenome:HGNC:2552 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to act upstream of or within protein catabolic process. Located in nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 12.7), brain (RPKM 7.3) and 25 other tissues See more Orthologs mouse all