ADRB1, Official Symbol ADRB1provided by HGNC Official Full Name adrenoceptor beta 1provided by HGNC Primary source HGNC:HGNC:285 See related Ensembl:ENSG00000043591 MIM:109630; AllianceGenome:HGNC:285 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RHR; B1AR; FNSS2; ADRB1R; BETA1AR Summary The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019] Orthologs mouse all