PI4KA, Official Symbol PI4KAprovided by HGNC Official Full Name phosphatidylinositol 4-kinase alphaprovided by HGNC Primary source HGNC:HGNC:8983 See related Ensembl:ENSG00000241973 MIM:600286; AllianceGenome:HGNC:8983 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPG84; GIDID2; PIK4CA; PMGYCHA; pi4K230; PI4K-ALPHA Summary This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2018] Expression Ubiquitous expression in brain (RPKM 52.3), testis (RPKM 23.0) and 24 other tissues See more Orthologs mouse all