ACOX3, Official Symbol ACOX3provided by HGNC Official Full Name acyl-CoA oxidase 3, pristanoylprovided by HGNC Primary source HGNC:HGNC:121 See related Ensembl:ENSG00000087008 MIM:603402; AllianceGenome:HGNC:121 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in esophagus (RPKM 3.5), skin (RPKM 3.1) and 25 other tissues See more Orthologs mouse all