SMC6, Official Symbol SMC6provided by HGNC Official Full Name structural maintenance of chromosomes 6provided by HGNC Primary source HGNC:HGNC:20466 See related Ensembl:ENSG00000163029 MIM:609387; AllianceGenome:HGNC:20466 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SMC-6; hSMC6; SMC6L1 Summary Enables ubiquitin protein ligase binding activity. Involved in several processes, including cellular senescence; positive regulation of chromosome segregation; and telomere maintenance via recombination. Located in chromosome and nuclear body. Part of Smc5-Smc6 complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 13.9), lymph node (RPKM 7.0) and 24 other tissues See more Orthologs mouse all