GCA, Official Symbol GCAprovided by HGNC Official Full Name grancalcinprovided by HGNC Primary source HGNC:HGNC:15990 See related Ensembl:ENSG00000115271 MIM:607030; AllianceGenome:HGNC:15990 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GCL Summary This gene encodes a calcium-binding protein that is abundant in neutrophils and macrophages. In the absence of divalent cation, this protein localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions. Alternative splicing and use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Aug 2016] Expression Broad expression in bone marrow (RPKM 47.3), appendix (RPKM 18.4) and 18 other tissues See more Orthologs mouse all