MUC20, Official Symbol MUC20provided by HGNC Official Full Name mucin 20, cell surface associatedprovided by HGNC Primary source HGNC:HGNC:23282 See related Ensembl:ENSG00000176945 MIM:610360; AllianceGenome:HGNC:23282 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MUC-20 Summary This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The C-terminus of this family member associates with the multifunctional docking site of the MET proto-oncogene and suppresses activation of some downstream MET signaling cascades. The protein features a mucin tandem repeat domain that varies between two and six copies in most individuals. Multiple variants encoding different isoforms have been found for this gene. A related pseudogene, which is also located on chromosome 3, has been identified. [provided by RefSeq, Apr 2014] Expression Broad expression in gall bladder (RPKM 28.1), colon (RPKM 25.9) and 17 other tissues See more Orthologs mouse all