KMO, Official Symbol KMOprovided by HGNC Official Full Name kynurenine 3-monooxygenaseprovided by HGNC Primary source HGNC:HGNC:6381 See related Ensembl:ENSG00000117009 MIM:603538; AllianceGenome:HGNC:6381 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dJ317G22.1 Summary This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease. [provided by RefSeq, Oct 2011] Expression Broad expression in liver (RPKM 11.5), kidney (RPKM 9.8) and 20 other tissues See more Orthologs mouse all