CD28, Official Symbol CD28provided by HGNC Official Full Name CD28 moleculeprovided by HGNC Primary source HGNC:HGNC:1653 See related Ensembl:ENSG00000178562 MIM:186760; AllianceGenome:HGNC:1653 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Tp44 Summary The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] Expression Biased expression in lymph node (RPKM 11.2), appendix (RPKM 7.3) and 7 other tissues See more Orthologs mouse all