INTS3, Official Symbol INTS3provided by HGNC Official Full Name integrator complex subunit 3provided by HGNC Primary source HGNC:HGNC:26153 See related Ensembl:ENSG00000143624 MIM:611347; AllianceGenome:HGNC:26153 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as INT3; SOSSA; SOSS-A; C1orf60; C1orf193 Summary The protein encoded by this gene can form a complex with human single-strand DNA binding proteins 1 or 2 (hSSB1 and hSSB2) and other proteins to mediate genome stability and the DNA damage response. The encoded protein is also part of a multiprotein complex that interacts with the C-terminal domain of RNA polymerase II large subunit to help regulate processing of U1 and U2 small nuclear RNAs. [provided by RefSeq, May 2016] Expression Ubiquitous expression in testis (RPKM 20.6), ovary (RPKM 17.9) and 25 other tissues See more Orthologs mouse all