GABRG2, Official Symbol GABRG2provided by HGNC Official Full Name gamma-aminobutyric acid type A receptor subunit gamma2provided by HGNC Primary source HGNC:HGNC:4087 See related Ensembl:ENSG00000113327 MIM:137164; AllianceGenome:HGNC:4087 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAE2; ECA2; FEB8; DEE74; EIEE74; GEFSP3 Summary This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Restricted expression toward brain (RPKM 32.3) See more Orthologs mouse all