KLHDC10, Official Symbol KLHDC10provided by HGNC Official Full Name kelch domain containing 10provided by HGNC Primary source HGNC:HGNC:22194 See related Ensembl:ENSG00000128607 MIM:615152; AllianceGenome:HGNC:22194 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as slim; PNAS-138 Summary Enables ubiquitin ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in nucleoplasm. Is active in Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 13.1), thyroid (RPKM 12.0) and 25 other tissues See more Orthologs mouse all