LRRCC1, Official Symbol LRRCC1provided by HGNC Official Full Name leucine rich repeat and coiled-coil centrosomal protein 1provided by HGNC Primary source HGNC:HGNC:29373 See related Ensembl:ENSG00000133739 MIM:617791; AllianceGenome:HGNC:29373 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAP2; VFL1; CLERC; CLERK Summary This gene encodes a centrosomal protein that maintains the structural integrity of the centrosome and plays a key role in mitotic spindle formation. The encoded protein contains an N-terminal leucine-rich repeat domain and a C-terminal coiled-coil domain. It associates with the centrosome throughout the cell cycle and accumulates on the mitotic centrosome. [provided by RefSeq, Mar 2017] Expression Broad expression in testis (RPKM 21.8), thyroid (RPKM 6.5) and 23 other tissues See more Orthologs mouse all