KCNIP2, Official Symbol KCNIP2provided by HGNC Official Full Name potassium voltage-gated channel interacting protein 2provided by HGNC Primary source HGNC:HGNC:15522 See related Ensembl:ENSG00000120049 MIM:604661; AllianceGenome:HGNC:15522 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KCHIP2 Summary This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in fat (RPKM 117.8), heart (RPKM 37.5) and 1 other tissue See more Orthologs mouse all