CHTF18, Official Symbol CHTF18provided by HGNC Official Full Name chromosome transmission fidelity factor 18provided by HGNC Primary source HGNC:HGNC:18435 See related Ensembl:ENSG00000127586 MIM:613201; AllianceGenome:HGNC:18435 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHL12; Ctf18; RUVBL; C16orf41; C321D2.2; C321D2.3; C321D2.4 Summary This gene encodes a protein which is a component of a replication factor C (RFC) complex, which loads proliferating cell nuclear antigen (PCNA) on to DNA during the S phase of cell cycle. The encoded protein may interact with other proteins, including RFC complex 3, to form a clamp loader complex that plays a role in sister chromatid cohesion during metaphase-anaphase transition. [provided by RefSeq, Jan 2016] Expression Broad expression in bone marrow (RPKM 7.1), testis (RPKM 6.3) and 24 other tissues See more Orthologs mouse all