PRDM1, Official Symbol PRDM1provided by HGNC Official Full Name PR/SET domain 1provided by HGNC Primary source HGNC:HGNC:9346 See related Ensembl:ENSG00000057657 MIM:603423; AllianceGenome:HGNC:9346 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BLIMP1; PRDI-BF1 Summary This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008] Expression Broad expression in esophagus (RPKM 16.3), endometrium (RPKM 7.2) and 17 other tissues See more Orthologs mouse all