NUDT18, Official Symbol NUDT18provided by HGNC Official Full Name nudix hydrolase 18provided by HGNC Primary source HGNC:HGNC:26194 See related Ensembl:ENSG00000275074 MIM:615791; AllianceGenome:HGNC:26194 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MTH3 Summary The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. This protein contains a Nudix hydrolase domain and hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates. [provided by RefSeq, Sep 2012] Expression Ubiquitous expression in spleen (RPKM 3.1), lymph node (RPKM 2.8) and 25 other tissues See more Orthologs mouse all