ZFYVE16, Official Symbol ZFYVE16provided by HGNC Official Full Name zinc finger FYVE-type containing 16provided by HGNC Primary source HGNC:HGNC:20756 See related Ensembl:ENSG00000039319 MIM:608880; AllianceGenome:HGNC:20756 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PPP1R69 Summary This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in brain (RPKM 10.1), endometrium (RPKM 9.9) and 25 other tissues See more Orthologs mouse all