MLLT3, Official Symbol MLLT3provided by HGNC Official Full Name MLLT3 super elongation complex subunitprovided by HGNC Primary source HGNC:HGNC:7136 See related Ensembl:ENSG00000171843 MIM:159558; AllianceGenome:HGNC:7136 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AF9; YEATS3 Summary Enables chromatin binding activity and lysine-acetylated histone binding activity. Involved in several processes, including hematopoietic stem cell differentiation; positive regulation of transcription, DNA-templated; and regulation of stem cell division. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and positive regulation of Wnt signaling pathway, planar cell polarity pathway. Located in cytosol and nucleoplasm. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 6.2), colon (RPKM 4.6) and 23 other tissues See more Orthologs mouse all