BHLHE23, Official Symbol BHLHE23provided by HGNC Official Full Name basic helix-loop-helix family member e23provided by HGNC Primary source HGNC:HGNC:16093 See related Ensembl:ENSG00000125533 MIM:609331; AllianceGenome:HGNC:16093 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BETA4; BHLHB4; Beta3b; bA305P22.3 Summary This gene encodes a member of the basic helix-loop-helix transcription factor family. Members of this family contain two highly conserved and functionally distinct domains: the basic domain targets sequence-specific DNA binding, while the helix-loop-helix domain facilitates protein interaction. Studies of a related gene in mouse suggest that the encoded protein may function as a transcriptional repressor in the pancreas and brain, and that it is required for normal retinal function. [provided by RefSeq, May 2013] Orthologs mouse all