SDS, Official Symbol SDSprovided by HGNC Official Full Name serine dehydrataseprovided by HGNC Primary source HGNC:HGNC:10691 See related Ensembl:ENSG00000135094 MIM:182128; AllianceGenome:HGNC:10691 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SDH Summary This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 130.0) and brain (RPKM 4.0) See more Orthologs mouse all