GFER, Official Symbol GFERprovided by HGNC Official Full Name growth factor, augmenter of liver regenerationprovided by HGNC Primary source HGNC:HGNC:4236 See related Ensembl:ENSG00000127554 MIM:600924; AllianceGenome:HGNC:4236 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALR; HPO; HSS; ERV1; HPO1; HPO2; HERV1; MMCHD; MPMCD Summary The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in small intestine (RPKM 7.8), duodenum (RPKM 7.7) and 25 other tissues See more Orthologs mouse all