PPP2R5E, Official Symbol PPP2R5Eprovided by HGNC Official Full Name protein phosphatase 2 regulatory subunit B'epsilonprovided by HGNC Primary source HGNC:HGNC:9313 See related Ensembl:ENSG00000154001 MIM:601647; AllianceGenome:HGNC:9313 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B56E; B56epsilon Summary The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in thyroid (RPKM 11.5), colon (RPKM 9.9) and 25 other tissues See more Orthologs mouse all