KRT18, Official Symbol KRT18provided by HGNC Official Full Name keratin 18provided by HGNC Primary source HGNC:HGNC:6430 See related Ensembl:ENSG00000111057 MIM:148070; AllianceGenome:HGNC:6430 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K18; CK-18; CYK18 Summary KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in placenta (RPKM 258.0), colon (RPKM 230.1) and 15 other tissues See more Orthologs mouse all