RP9, Official Symbol RP9provided by HGNC Official Full Name RP9 pre-mRNA splicing factorprovided by HGNC Primary source HGNC:HGNC:10288 See related Ensembl:ENSG00000164610 MIM:607331; AllianceGenome:HGNC:10288 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAP1; PAP-1 Summary The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene. [provided by RefSeq, Sep 2009] Expression Ubiquitous expression in testis (RPKM 5.1), adrenal (RPKM 4.6) and 25 other tissues See more Orthologs mouse all