PPP5C, Official Symbol PPP5Cprovided by HGNC Official Full Name protein phosphatase 5 catalytic subunitprovided by HGNC Primary source HGNC:HGNC:9322 See related Ensembl:ENSG00000011485 MIM:600658; AllianceGenome:HGNC:9322 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP5; PPT; PPP5 Summary This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011] Expression Ubiquitous expression in heart (RPKM 18.5), brain (RPKM 17.4) and 25 other tissues See more Orthologs mouse all