RHBDL1, Official Symbol RHBDL1provided by HGNC Official Full Name rhomboid like 1provided by HGNC Primary source HGNC:HGNC:10007 See related Ensembl:ENSG00000103269 MIM:603264; AllianceGenome:HGNC:10007 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RRP; RHBDL Summary This gene encodes a protein similar to Rhomboid in Drosophila which is involved in signalling in the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. The Rhomboid family of proteins consists of intramembrane serine proteases containing several transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] Expression Broad expression in brain (RPKM 2.4), kidney (RPKM 1.5) and 21 other tissues See more Orthologs mouse all