CEBPB, Official Symbol CEBPBprovided by HGNC Official Full Name CCAAT enhancer binding protein betaprovided by HGNC Primary source HGNC:HGNC:1834 See related Ensembl:ENSG00000172216 MIM:189965; AllianceGenome:HGNC:1834 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCF5; IL6DBP; NF-IL6; C/EBP-beta Summary This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013] Orthologs mouse all