SYT6, Official Symbol SYT6provided by HGNC Official Full Name synaptotagmin 6provided by HGNC Primary source HGNC:HGNC:18638 See related Ensembl:ENSG00000134207 MIM:607718; AllianceGenome:HGNC:18638 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as sytVI Summary The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011] Expression Biased expression in brain (RPKM 2.6), kidney (RPKM 0.8) and 6 other tissues See more Orthologs mouse all