CAMK2N2, Official Symbol CAMK2N2provided by HGNC Official Full Name calcium/calmodulin dependent protein kinase II inhibitor 2provided by HGNC Primary source HGNC:HGNC:24197 See related Ensembl:ENSG00000163888 MIM:608721; AllianceGenome:HGNC:24197 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAMKIIN; CAM-KIIN Summary This gene encodes a protein that is highly similar to the rat CaM-KII inhibitory protein, an inhibitor of calcium/calmodulin-dependent protein kinase II (CAMKII). CAMKII regulates numerous physiological functions, including neuronal synaptic plasticity through the phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate (AMPA) receptors. Studies of the similar protein in rat suggest that this protein may function as a negative regulator of CaM-KII and may act to inhibit the phosphorylation of AMPA receptors. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 13.3), adrenal (RPKM 4.9) and 1 other tissue See more Orthologs mouse all