STAG2, Official Symbol STAG2provided by HGNC Official Full Name STAG2 cohesin complex componentprovided by HGNC Primary source HGNC:HGNC:11355 See related Ensembl:ENSG00000101972 MIM:300826; AllianceGenome:HGNC:11355 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SA2; MKMS; SA-2; HPE13; SCC3B; NEDXCF; bA517O1.1 Summary The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in thyroid (RPKM 24.4), bone marrow (RPKM 22.3) and 25 other tissues See more Orthologs mouse all