RBM14, Official Symbol RBM14provided by HGNC Official Full Name RNA binding motif protein 14provided by HGNC Primary source HGNC:HGNC:14219 See related Ensembl:ENSG00000239306 MIM:612409; AllianceGenome:HGNC:14219 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIP; COAA; PSP2; SYTIP1; TMEM137 Summary This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011] Annotation information Note: The nomenclature TMEM137, transmembrane protein 137 was assigned to BC024260, which is now thought to represent the 3' UTR of RBM14. [15 Aug 2008] Expression Ubiquitous expression in testis (RPKM 11.0), lymph node (RPKM 7.8) and 25 other tissues See more Orthologs mouse all