TREM1, Official Symbol TREM1provided by HGNC Official Full Name triggering receptor expressed on myeloid cells 1provided by HGNC Primary source HGNC:HGNC:17760 See related Ensembl:ENSG00000124731 MIM:605085; AllianceGenome:HGNC:17760 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD354; TREM-1 Summary This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] Expression Biased expression in bone marrow (RPKM 10.0), appendix (RPKM 9.0) and 7 other tissues See more Orthologs mouse all