ACOT8, Official Symbol ACOT8provided by HGNC Official Full Name acyl-CoA thioesterase 8provided by HGNC Primary source HGNC:HGNC:15919 See related Ensembl:ENSG00000101473 MIM:608123; AllianceGenome:HGNC:15919 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hTE; NAP1; PTE1; PTE2; PTE-1; PTE-2; HNAACTE; hACTE-III Summary The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. [provided by RefSeq, Oct 2010] Expression Ubiquitous expression in adrenal (RPKM 10.6), brain (RPKM 10.3) and 25 other tissues See more Orthologs mouse all