CSF1, Official Symbol CSF1provided by HGNC Official Full Name colony stimulating factor 1provided by HGNC Primary source HGNC:HGNC:2432 See related Ensembl:ENSG00000184371 MIM:120420; AllianceGenome:HGNC:2432 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCSF; CSF-1; PG-M-CSF Summary The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in placenta (RPKM 19.9), spleen (RPKM 19.7) and 25 other tissues See more Orthologs mouse all