CHN1, Official Symbol CHN1provided by HGNC Official Full Name chimerin 1provided by HGNC Primary source HGNC:HGNC:1943 See related Ensembl:ENSG00000128656 MIM:118423; AllianceGenome:HGNC:1943 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NC; CHN; DURS2; ARHGAP2; RHOGAP2 Summary This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011] Expression Biased expression in brain (RPKM 113.6), placenta (RPKM 8.8) and 1 other tissue See more Orthologs mouse all