SCNN1B, Official Symbol SCNN1Bprovided by HGNC Official Full Name sodium channel epithelial 1 subunit betaprovided by HGNC Primary source HGNC:HGNC:10600 See related Ensembl:ENSG00000168447 MIM:600760; AllianceGenome:HGNC:10600 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BESC1; ENaCb; SCNEB; LIDLS1; PHA1B2; ENaCbeta; beta-ENaC; beta-NaCH Summary Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009] Expression Biased expression in esophagus (RPKM 18.7), colon (RPKM 18.2) and 11 other tissues See more Orthologs mouse all