KCNK10, Official Symbol KCNK10provided by HGNC Official Full Name potassium two pore domain channel subfamily K member 10provided by HGNC Primary source HGNC:HGNC:6273 See related Ensembl:ENSG00000100433 MIM:605873; AllianceGenome:HGNC:6273 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TREK2; TREK-2; K2p10.1; PPP1R97 Summary The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008] Expression Biased expression in brain (RPKM 1.7), duodenum (RPKM 1.4) and 8 other tissues See more Orthologs mouse all