HSD17B12, Official Symbol HSD17B12provided by HGNC Official Full Name hydroxysteroid 17-beta dehydrogenase 12provided by HGNC Primary source HGNC:HGNC:18646 See related Ensembl:ENSG00000149084 MIM:609574; AllianceGenome:HGNC:18646 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KAR; SDR12C1 Summary This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011] Expression Ubiquitous expression in brain (RPKM 34.2), kidney (RPKM 34.0) and 25 other tissues See more Orthologs mouse all