PTGIR, Official Symbol PTGIRprovided by HGNC Official Full Name prostaglandin I2 receptorprovided by HGNC Primary source HGNC:HGNC:9602 See related Ensembl:ENSG00000160013 MIM:600022; AllianceGenome:HGNC:9602 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IP; PRIPR Summary The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 50.8), placenta (RPKM 17.2) and 24 other tissues See more Orthologs mouse all