ENTPD4, Official Symbol ENTPD4provided by HGNC Official Full Name ectonucleoside triphosphate diphosphohydrolase 4provided by HGNC Primary source HGNC:HGNC:14573 See related Ensembl:ENSG00000197217 MIM:607577; AllianceGenome:HGNC:14573 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LAP70; LALP70; LYSAL1; UDPase; NTPDase-4 Summary This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in lymph node (RPKM 16.0), appendix (RPKM 14.8) and 25 other tissues See more Orthologs all