DLEC1, Official Symbol DLEC1provided by HGNC Official Full Name DLEC1 cilia and flagella associated proteinprovided by HGNC Primary source HGNC:HGNC:2899 See related Ensembl:ENSG00000008226 MIM:604050; AllianceGenome:HGNC:2899 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as F56; DLC1; DLC-1; FAP81; CFAP81 Summary The cytogenetic location of this gene is 3p21.3, and it is located in a region that is commonly deleted in a variety of malignancies. Down-regulation of this gene has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of this gene in tumor cells is a result of aberrant promoter methylation. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins.[provided by RefSeq, Mar 2016] Expression Biased expression in testis (RPKM 8.8), lung (RPKM 3.8) and 2 other tissues See more Orthologs mouse all