CRLF1, Official Symbol CRLF1provided by HGNC Official Full Name cytokine receptor like factor 1provided by HGNC Primary source HGNC:HGNC:2364 See related Ensembl:ENSG00000006016 MIM:604237; AllianceGenome:HGNC:2364 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLF; NR6; CISS; CISS1; CLF-1; zcytor5 Summary This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq, Oct 2009] Expression Broad expression in placenta (RPKM 4.8), brain (RPKM 3.2) and 15 other tissues See more Orthologs mouse all