GBP5, Official Symbol GBP5provided by HGNC Official Full Name guanylate binding protein 5provided by HGNC Primary source HGNC:HGNC:19895 See related Ensembl:ENSG00000154451 MIM:611467; AllianceGenome:HGNC:19895 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GBP-5 Summary This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017] Expression Biased expression in appendix (RPKM 33.2), lymph node (RPKM 19.8) and 11 other tissues See more Orthologs all