ASB1, Official Symbol ASB1provided by HGNC Official Full Name ankyrin repeat and SOCS box containing 1provided by HGNC Primary source HGNC:HGNC:16011 See related Ensembl:ENSG00000065802 MIM:605758; AllianceGenome:HGNC:16011 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ASB-1 Summary The protein encoded by this gene contains an ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, targeting them for ubiquitination and degradation. [provided by RefSeq, Aug 2016] Expression Ubiquitous expression in brain (RPKM 9.2), heart (RPKM 8.5) and 25 other tissues See more Orthologs mouse all