SYNJ2, Official Symbol SYNJ2provided by HGNC Official Full Name synaptojanin 2provided by HGNC Primary source HGNC:HGNC:11504 See related Ensembl:ENSG00000078269 MIM:609410; AllianceGenome:HGNC:11504 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as INPP5H Summary The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Expression Ubiquitous expression in brain (RPKM 8.6), colon (RPKM 3.7) and 25 other tissues See more Orthologs mouse all