DDAH2, Official Symbol DDAH2provided by HGNC Official Full Name DDAH family member 2, ADMA-independentprovided by HGNC Primary source HGNC:HGNC:2716 See related Ensembl:ENSG00000213722 MIM:604744; AllianceGenome:HGNC:2716 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G6a; DDAH; NG30; DDAHII; HEL-S-277 Summary This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in endometrium (RPKM 29.0), fat (RPKM 28.2) and 24 other tissues See more Orthologs mouse all