GSDMC, Official Symbol GSDMCprovided by HGNC Official Full Name gasdermin Cprovided by HGNC Primary source HGNC:HGNC:7151 See related Ensembl:ENSG00000147697 MIM:608384; AllianceGenome:HGNC:7151 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MLZE Summary Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Predicted to be involved in defense response to bacterium and pyroptosis. Predicted to act upstream of or within intestinal epithelial cell development. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in skin (RPKM 9.5), spleen (RPKM 4.6) and 1 other tissue See more Orthologs all