RPS6KA1, Official Symbol RPS6KA1provided by HGNC Official Full Name ribosomal protein S6 kinase A1provided by HGNC Primary source HGNC:HGNC:10430 See related Ensembl:ENSG00000117676 MIM:601684; AllianceGenome:HGNC:10430 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RSK; HU-1; RSK1; p90Rsk; MAPKAPK1; MAPKAPK1A Summary This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Broad expression in small intestine (RPKM 31.6), duodenum (RPKM 29.3) and 21 other tissues See more Orthologs mouse all