DUSP16, Official Symbol DUSP16provided by HGNC Official Full Name dual specificity phosphatase 16provided by HGNC Primary source HGNC:HGNC:17909 See related Ensembl:ENSG00000111266 MIM:607175; AllianceGenome:HGNC:17909 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKP7; MKP-7 Summary This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010] Expression Ubiquitous expression in adrenal (RPKM 19.6), liver (RPKM 13.0) and 25 other tissues See more Orthologs mouse all