NLRP13, Official Symbol NLRP13provided by HGNC Official Full Name NLR family pyrin domain containing 13provided by HGNC Primary source HGNC:HGNC:22937 See related Ensembl:ENSG00000173572 MIM:609660; AllianceGenome:HGNC:22937 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOD14; PAN13; NALP13; CLR19.7 Summary This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] Expression Low expression observed in reference dataset See more Orthologs all