TSC22D3, Official Symbol TSC22D3provided by HGNC Official Full Name TSC22 domain family member 3provided by HGNC Primary source HGNC:HGNC:3051 See related Ensembl:ENSG00000157514 MIM:300506; AllianceGenome:HGNC:3051 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DIP; GILZ; DSIPI; TSC-22R Summary This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor &#954;B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in fat (RPKM 114.8), appendix (RPKM 102.3) and 25 other tissues See more Orthologs mouse all