MYO7A, Official Symbol MYO7Aprovided by HGNC Official Full Name myosin VIIAprovided by HGNC Primary source HGNC:HGNC:7606 See related Ensembl:ENSG00000137474 MIM:276903; AllianceGenome:HGNC:7606 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNB2; MYU7A; NSRD2; USH1B; DFNA11; MYOVIIA Summary This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] Expression Broad expression in adrenal (RPKM 8.3), testis (RPKM 6.5) and 17 other tissues See more Orthologs mouse all