SUMO2, Official Symbol SUMO2provided by HGNC Official Full Name small ubiquitin like modifier 2provided by HGNC Primary source HGNC:HGNC:11125 See related Ensembl:ENSG00000188612 MIM:603042; AllianceGenome:HGNC:11125 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSMT3; SMT3B; SUMO3; Smt3A; SMT3H2 Summary This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in endometrium (RPKM 121.8), lymph node (RPKM 108.7) and 25 other tissues See more Orthologs mouse all