TOR2A, Official Symbol TOR2Aprovided by HGNC Official Full Name torsin family 2 member Aprovided by HGNC Primary source HGNC:HGNC:11996 See related Ensembl:ENSG00000160404 MIM:608052; AllianceGenome:HGNC:11996 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TORP1 Summary This gene encodes a member of the AAA family of adenosine triphosphatases with similarity to Clp proteases and heat shock proteins. Alternative splicing at this locus results in the translation of multiple isoforms of the encoded protein, some of which contain salusin peptides in the C-terminal region. These peptides may play roles in hypotension, myocardial growth and the induction of mitogenesis, and may also be involved in the pathogenesis of atherosclerosis. The antimicrobial peptide salusin-beta has antibacterial activity. [provided by RefSeq, Nov 2014] Expression Ubiquitous expression in bone marrow (RPKM 7.4), testis (RPKM 5.3) and 25 other tissues See more Orthologs mouse all