LIPI, Official Symbol LIPIprovided by HGNC Official Full Name lipase Iprovided by HGNC Primary source HGNC:HGNC:18821 See related Ensembl:ENSG00000188992 MIM:609252; AllianceGenome:HGNC:18821 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT17; LPDL; PLA1C; PRED5; mPA-PLA1 beta Summary The protein encoded by this gene is a phospholipase that hydrolyzes phosphatidic acid to produce lysophosphatidic acid. Defects in this gene are a cause of susceptibility to familial hypertrigliceridemia. This gene is also expressed at high levels in Ewing family tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Expression Biased expression in thyroid (RPKM 1.4), endometrium (RPKM 0.3) and 2 other tissues See more Orthologs mouse all