UPK2, Official Symbol UPK2provided by HGNC Official Full Name uroplakin 2provided by HGNC Primary source HGNC:HGNC:12579 See related Ensembl:ENSG00000110375 MIM:611558; AllianceGenome:HGNC:12579 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UP2; UPII Summary This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009] Expression Biased expression in urinary bladder (RPKM 26.3) and fat (RPKM 1.3) See more Orthologs mouse all