LSS, Official Symbol LSSprovided by HGNC Official Full Name lanosterol synthaseprovided by HGNC Primary source HGNC:HGNC:6708 See related Ensembl:ENSG00000160285 MIM:600909; AllianceGenome:HGNC:6708 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OSC; APMR4; HYPT14; CTRCT44 Summary The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009] Expression Ubiquitous expression in skin (RPKM 17.0), lung (RPKM 14.7) and 25 other tissues See more Orthologs mouse all