NGF, Official Symbol NGFprovided by HGNC Official Full Name nerve growth factorprovided by HGNC Primary source HGNC:HGNC:7808 See related Ensembl:ENSG00000134259 MIM:162030; AllianceGenome:HGNC:7808 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NGFB; HSAN5; Beta-NGF Summary This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008] Expression Broad expression in ovary (RPKM 1.3), heart (RPKM 0.5) and 18 other tissues See more Orthologs mouse all