NLRC5, Official Symbol NLRC5provided by HGNC Official Full Name NLR family CARD domain containing 5provided by HGNC Primary source HGNC:HGNC:29933 See related Ensembl:ENSG00000140853 MIM:613537; AllianceGenome:HGNC:29933 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOD4; NOD27; CLR16.1 Summary This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011] Expression Broad expression in spleen (RPKM 23.6), lymph node (RPKM 20.1) and 22 other tissues See more Orthologs mouse all