DCAF11, Official Symbol DCAF11provided by HGNC Official Full Name DDB1 and CUL4 associated factor 11provided by HGNC Primary source HGNC:HGNC:20258 See related Ensembl:ENSG00000100897 MIM:613317; AllianceGenome:HGNC:20258 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GL014; WDR23; PRO2389 Summary This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009] Expression Ubiquitous expression in liver (RPKM 25.7), small intestine (RPKM 25.5) and 25 other tissues See more Orthologs mouse all