PNMT, Official Symbol PNMTprovided by HGNC Official Full Name phenylethanolamine N-methyltransferaseprovided by HGNC Primary source HGNC:HGNC:9160 See related Ensembl:ENSG00000141744 MIM:171190; AllianceGenome:HGNC:9160 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PENT; PNMTase Summary The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] Expression Biased expression in adrenal (RPKM 46.5) and fat (RPKM 2.1) See more Orthologs mouse all