ATRIP, Official Symbol ATRIPprovided by HGNC Official Full Name ATR interacting proteinprovided by HGNC Primary source HGNC:HGNC:33499 See related Ensembl:ENSG00000164053 MIM:606605; AllianceGenome:HGNC:33499 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012] Annotation information Note: GeneID 11277 was annotated as a single gene with two non-overlapping coding regions. GeneID 11277 now represents only the downstream coding region encoding three prime repair exonuclease 1. The upstream coding region is represented by geneID 84126. [29 May 2007] Expression Broad expression in testis (RPKM 11.6), thyroid (RPKM 3.8) and 23 other tissues See more Orthologs mouse all