HERC1, Official Symbol HERC1provided by HGNC Official Full Name HECT and RLD domain containing E3 ubiquitin protein ligase family member 1provided by HGNC Primary source HGNC:HGNC:4867 See related Ensembl:ENSG00000103657 MIM:605109; AllianceGenome:HGNC:4867 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p532; p619; MDFPMR Summary This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes. [provided by RefSeq, Mar 2012] Expression Ubiquitous expression in brain (RPKM 7.7), ovary (RPKM 7.5) and 25 other tissues See more Orthologs mouse all