PRPF18, Official Symbol PRPF18provided by HGNC Official Full Name pre-mRNA processing factor 18provided by HGNC Primary source HGNC:HGNC:17351 See related Ensembl:ENSG00000165630 MIM:604993; AllianceGenome:HGNC:17351 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRP18; hPrp18 Summary Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 3.4), brain (RPKM 3.1) and 25 other tissues See more Orthologs mouse all