NOS2, Official Symbol NOS2provided by HGNC Official Full Name nitric oxide synthase 2provided by HGNC Primary source HGNC:HGNC:7873 See related Ensembl:ENSG00000007171 MIM:163730; AllianceGenome:HGNC:7873 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOS; INOS; NOS2A; HEP-NOS Summary Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] Expression Biased expression in small intestine (RPKM 10.3), appendix (RPKM 7.9) and 5 other tissues See more Orthologs mouse all