CMTM7, Official Symbol CMTM7provided by HGNC Official Full Name CKLF like MARVEL transmembrane domain containing 7provided by HGNC Primary source HGNC:HGNC:19178 See related Ensembl:ENSG00000153551 MIM:607890; AllianceGenome:HGNC:19178 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CKLFSF7 Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] Expression Broad expression in lymph node (RPKM 7.5), spleen (RPKM 7.1) and 25 other tissues See more Orthologs mouse all