PRICKLE2, Official Symbol PRICKLE2provided by HGNC Official Full Name prickle planar cell polarity protein 2provided by HGNC Primary source HGNC:HGNC:20340 See related Ensembl:ENSG00000163637 MIM:608501; AllianceGenome:HGNC:20340 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPM5 Summary This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011] Expression Broad expression in endometrium (RPKM 7.1), brain (RPKM 5.6) and 22 other tissues See more Orthologs mouse all