CRLF3, Official Symbol CRLF3provided by HGNC Official Full Name cytokine receptor like factor 3provided by HGNC Primary source HGNC:HGNC:17177 See related Ensembl:ENSG00000176390 MIM:614853; AllianceGenome:HGNC:17177 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FRWS; CRLM9; p48.2; CREME9; CYTOR4; CREME-9 Summary This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5. [provided by RefSeq, Aug 2012] Expression Broad expression in lymph node (RPKM 15.5), appendix (RPKM 12.1) and 24 other tissues See more Orthologs mouse all