TCTN3, Official Symbol TCTN3provided by HGNC Official Full Name tectonic family member 3provided by HGNC Primary source HGNC:HGNC:24519 See related Ensembl:ENSG00000119977 MIM:613847; AllianceGenome:HGNC:24519 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OFD4; TECT3; JBTS18; C10orf61 Summary This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012] Expression Ubiquitous expression in thyroid (RPKM 49.4), ovary (RPKM 15.6) and 25 other tissues See more Orthologs mouse all