ADAMTS16, Official Symbol ADAMTS16provided by HGNC Official Full Name ADAM metallopeptidase with thrombospondin type 1 motif 16provided by HGNC Primary source HGNC:HGNC:17108 See related Ensembl:ENSG00000145536 MIM:607510; AllianceGenome:HGNC:17108 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADAMTS16s Summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure. [provided by RefSeq, May 2016] Expression Biased expression in ovary (RPKM 5.4), gall bladder (RPKM 4.3) and 8 other tissues See more Orthologs mouse all