SOX30, Official Symbol SOX30provided by HGNC Official Full Name SRY-box transcription factor 30provided by HGNC Primary source HGNC:HGNC:30635 See related Ensembl:ENSG00000039600 MIM:606698; AllianceGenome:HGNC:30635 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Apr 2015] Expression Restricted expression toward testis (RPKM 26.2) See more Orthologs mouse all