KIF12, Official Symbol KIF12provided by HGNC Official Full Name kinesin family member 12provided by HGNC Primary source HGNC:HGNC:21495 See related Ensembl:ENSG00000136883 MIM:611278; AllianceGenome:HGNC:21495 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PFIC8 Summary This gene encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance. [provided by RefSeq, Jul 2016] Expression Biased expression in kidney (RPKM 28.1), gall bladder (RPKM 9.6) and 9 other tissues See more Orthologs mouse all