PNPLA3, Official Symbol PNPLA3provided by HGNC Official Full Name patatin like phospholipase domain containing 3provided by HGNC Primary source HGNC:HGNC:18590 See related Ensembl:ENSG00000100344 MIM:609567; AllianceGenome:HGNC:18590 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADPN; C22orf20; iPLA(2)epsilon Summary The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 8.6), kidney (RPKM 3.4) and 4 other tissues See more Orthologs mouse all