ACSM2A, Official Symbol ACSM2Aprovided by HGNC Official Full Name acyl-CoA synthetase medium chain family member 2Aprovided by HGNC Primary source HGNC:HGNC:32017 See related Ensembl:ENSG00000183747 MIM:614358; AllianceGenome:HGNC:32017 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACSM2; A-923A4.1 Summary This gene encodes a mitochondrial acyl-coenzyme A synthetase that is specific for medium chain fatty acids. These enzymes catalyze fatty acid activation, the first step of fatty acid metabolism, through the transfer of acyl-CoA. These enzymes also participate in the glycine conjugation pathway in the detoxification of xenobiotics such as benzoate and ibuprofen. Expression levels of this gene in the kidney may be correlated with kidney function. This gene and its paralog ACSM2B (Gene ID: 348158), both present on chromosome 16, likely arose from a chromosomal duplication event. [provided by RefSeq, May 2017] Expression Restricted expression toward kidney (RPKM 83.2) See more Orthologs all