BHLHE22, Official Symbol BHLHE22provided by HGNC Official Full Name basic helix-loop-helix family member e22provided by HGNC Primary source HGNC:HGNC:11963 See related Ensembl:ENSG00000180828 MIM:613483; AllianceGenome:HGNC:11963 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Beta3; BHLHB5; Beta3a; CAGL85; TNRC20 Summary This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors that regulate cell fate determination, proliferation, and differentiation. A similar protein in mouse is required for the development of the dorsal cochlear nuclei, and is thought to play a role in in the differentiation of neurons involved in sensory input. The mouse protein also functions in retinogenesis. [provided by RefSeq, Oct 2016] Orthologs mouse all