ATG12, Official Symbol ATG12provided by HGNC Official Full Name autophagy related 12provided by HGNC Primary source HGNC:HGNC:588 See related Ensembl:ENSG00000145782 MIM:609608; AllianceGenome:HGNC:588 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APG12; FBR93; APG12L; HAPG12 Summary Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in brain (RPKM 8.9), fat (RPKM 8.2) and 25 other tissues See more Orthologs mouse all