MR1, Official Symbol MR1provided by HGNC Official Full Name major histocompatibility complex, class I-relatedprovided by HGNC Primary source HGNC:HGNC:4975 See related Ensembl:ENSG00000153029 MIM:600764; AllianceGenome:HGNC:4975 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HLALS Summary MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome. [provided by RefSeq, Jul 2015] Expression Ubiquitous expression in urinary bladder (RPKM 6.3), thyroid (RPKM 5.6) and 24 other tissues See more Orthologs mouse all