MTAP, Official Symbol MTAPprovided by HGNC Official Full Name methylthioadenosine phosphorylaseprovided by HGNC Primary source HGNC:HGNC:7413 See related Ensembl:ENSG00000099810 MIM:156540; AllianceGenome:HGNC:7413 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249 Summary This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2021] Expression Ubiquitous expression in ovary (RPKM 5.5), esophagus (RPKM 5.2) and 25 other tissues See more Orthologs mouse all