GPR3, Official Symbol GPR3provided by HGNC Official Full Name G protein-coupled receptor 3provided by HGNC Primary source HGNC:HGNC:4484 See related Ensembl:ENSG00000181773 MIM:600241; AllianceGenome:HGNC:4484 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACCA Summary This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease. [provided by RefSeq, Oct 2012] Expression Broad expression in brain (RPKM 2.0), thyroid (RPKM 0.6) and 17 other tissues See more Orthologs mouse all