AP2S1, Official Symbol AP2S1provided by HGNC Official Full Name adaptor related protein complex 2 subunit sigma 1provided by HGNC Primary source HGNC:HGNC:565 See related Ensembl:ENSG00000042753 MIM:602242; AllianceGenome:HGNC:565 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AP17; FBH3; HHC3; FBHOk; CLAPS2 Summary One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in placenta (RPKM 25.3), brain (RPKM 23.2) and 25 other tissues See more Orthologs mouse all