APOA4, Official Symbol APOA4provided by HGNC Official Full Name apolipoprotein A4provided by HGNC Primary source HGNC:HGNC:602 See related Ensembl:ENSG00000110244 MIM:107690; AllianceGenome:HGNC:602 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro. [provided by RefSeq, Jul 2008] Expression Restricted expression toward small intestine (RPKM 1486.2) See more Orthologs mouse all