WNT10A, Official Symbol WNT10Aprovided by HGNC Official Full Name Wnt family member 10Aprovided by HGNC Primary source HGNC:HGNC:13829 See related Ensembl:ENSG00000135925 MIM:606268; AllianceGenome:HGNC:13829 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OODD; SSPS; ECTD16; STHAG4 Summary The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 2008] Expression Broad expression in skin (RPKM 3.0), placenta (RPKM 1.8) and 16 other tissues See more Orthologs mouse all