FOXA3, Official Symbol FOXA3provided by HGNC Official Full Name forkhead box A3provided by HGNC Primary source HGNC:HGNC:5023 See related Ensembl:ENSG00000170608 MIM:602295; AllianceGenome:HGNC:5023 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FKHH3; HNF3G; TCF3G Summary This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 21.0), stomach (RPKM 17.8) and 6 other tissues See more Orthologs mouse all