GOT1, Official Symbol GOT1provided by HGNC Official Full Name glutamic-oxaloacetic transaminase 1provided by HGNC Primary source HGNC:HGNC:4432 See related Ensembl:ENSG00000120053 MIM:138180; AllianceGenome:HGNC:4432 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AST; AST1; SGOT; cCAT; GIG18; cAspAT; ASTQTL1 Summary Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. [provided by RefSeq, Jul 2008] Expression Broad expression in heart (RPKM 196.1), liver (RPKM 87.7) and 14 other tissues See more Orthologs mouse all