ADRB3, Official Symbol ADRB3provided by HGNC Official Full Name adrenoceptor beta 3provided by HGNC Primary source HGNC:HGNC:288 See related Ensembl:ENSG00000188778 MIM:109691; AllianceGenome:HGNC:288 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BETA3AR Summary The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019] Expression Biased expression in ovary (RPKM 4.0), placenta (RPKM 1.7) and 3 other tissues See more Orthologs mouse all