CUBN, Official Symbol CUBNprovided by HGNC Official Full Name cubilinprovided by HGNC Primary source HGNC:HGNC:2548 See related Ensembl:ENSG00000107611 MIM:602997; AllianceGenome:HGNC:2548 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IGS; IFCR; IGS1; MGA1; gp280 Summary Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 65.4) and small intestine (RPKM 9.4) See more Orthologs mouse all