GUCY2F, Official Symbol GUCY2Fprovided by HGNC Official Full Name guanylate cyclase 2F, retinalprovided by HGNC Primary source HGNC:HGNC:4691 See related Ensembl:ENSG00000101890 MIM:300041; AllianceGenome:HGNC:4691 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CYGF; GC-F; GUC2F; GUC2DL; RETGC-2; ROS-GC2 Summary The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all