RNF41, Official Symbol RNF41provided by HGNC Official Full Name ring finger protein 41provided by HGNC Primary source HGNC:HGNC:18401 See related Ensembl:ENSG00000181852 MIM:620051; AllianceGenome:HGNC:18401 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FLRF; NRDP1; SBBI03 Summary This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011] Expression Ubiquitous expression in brain (RPKM 10.6), prostate (RPKM 9.7) and 25 other tissues See more Orthologs mouse all