LHB, Official Symbol LHBprovided by HGNC Official Full Name luteinizing hormone subunit betaprovided by HGNC Primary source HGNC:HGNC:6584 See related Ensembl:ENSG00000104826 MIM:152780; AllianceGenome:HGNC:6584 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CGB4; HH23; LSH-B; LSH-beta Summary This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008] Expression Biased expression in pancreas (RPKM 1.7), testis (RPKM 1.1) and 7 other tissues See more Orthologs mouse all