DENND6A, Official Symbol DENND6Aprovided by HGNC Official Full Name DENN domain containing 6Aprovided by HGNC Primary source HGNC:HGNC:26635 See related Ensembl:ENSG00000174839 AllianceGenome:HGNC:26635 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AFI1A; FAM116A Summary Enables guanyl-nucleotide exchange factor activity. Involved in positive regulation of cell-cell adhesion mediated by cadherin. Located in recycling endosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 8.9), thyroid (RPKM 8.0) and 25 other tissues See more Orthologs mouse all