IFI27, Official Symbol IFI27provided by HGNC Official Full Name interferon alpha inducible protein 27provided by HGNC Primary source HGNC:HGNC:5397 See related Ensembl:ENSG00000165949 MIM:600009; AllianceGenome:HGNC:5397 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P27; ISG12; FAM14D; ISG12A Summary Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; identical protein binding activity; and lamin binding activity. Involved in several processes, including cellular protein metabolic process; defense response to other organism; and extrinsic apoptotic signaling pathway. Acts upstream of or within negative regulation of transcription by RNA polymerase II and regulation of protein export from nucleus. Located in mitochondrial membrane and nuclear inner membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in stomach (RPKM 224.1), spleen (RPKM 211.7) and 21 other tissues See more Orthologs all