NUP188, Official Symbol NUP188provided by HGNC Official Full Name nucleoporin 188provided by HGNC Primary source HGNC:HGNC:17859 See related Ensembl:ENSG00000095319 MIM:615587; AllianceGenome:HGNC:17859 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hNup188; KIAA0169; SANDSTEF Summary The nuclear pore complex (NPC) is found on the nuclear envelope and forms a gateway that regulates the flow of proteins and RNAs between the cytoplasm and nucleoplasm. The NPC is comprised of approximately 30 distinct proteins collectively known as nucleoporins. Nucleoporins are pore-complex-specific glycoproteins which often have cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. However, the nucleoporin protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. This nucleoporin is thought to form part of the scaffold for the central channel of the nuclear pore. [provided by RefSeq, Jan 2013] Expression Broad expression in testis (RPKM 47.7), skin (RPKM 10.9) and 23 other tissues See more Orthologs mouse all