DLX5, Official Symbol DLX5provided by HGNC Official Full Name distal-less homeobox 5provided by HGNC Primary source HGNC:HGNC:2918 See related Ensembl:ENSG00000105880 MIM:600028; AllianceGenome:HGNC:2918 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SHFM1; SHFM1D Summary This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 4.3), placenta (RPKM 4.0) and 9 other tissues See more Orthologs mouse all