STXBP3, Official Symbol STXBP3provided by HGNC Official Full Name syntaxin binding protein 3provided by HGNC Primary source HGNC:HGNC:11446 See related Ensembl:ENSG00000116266 MIM:608339; AllianceGenome:HGNC:11446 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PSP; MUNC18C; UNC-18C; MUNC18-3 Summary Enables syntaxin binding activity. Involved in negative regulation of calcium ion-dependent exocytosis; neutrophil degranulation; and platelet aggregation. Located in cytosol; plasma membrane; and secretory granule. Is active in presynapse. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 25.5), kidney (RPKM 20.8) and 25 other tissues See more Orthologs mouse all