MICAL2, Official Symbol MICAL2provided by HGNC Official Full Name microtubule associated monooxygenase, calponin and LIM domain containing 2provided by HGNC Primary source HGNC:HGNC:24693 See related Ensembl:ENSG00000133816 MIM:608881; AllianceGenome:HGNC:24693 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MICAL-2; MICALCL; Ebitein1; mical-cL; MICAL2PV1; MICAL2PV2 Summary The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016] Expression Broad expression in testis (RPKM 23.1), colon (RPKM 17.9) and 24 other tissues See more Orthologs mouse all