MAPK6, Official Symbol MAPK6provided by HGNC Official Full Name mitogen-activated protein kinase 6provided by HGNC Primary source HGNC:HGNC:6879 See related Ensembl:ENSG00000069956 MIM:602904; AllianceGenome:HGNC:6879 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ERK3; PRKM6; p97MAPK; HsT17250 Summary The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 25.2), brain (RPKM 20.8) and 25 other tissues See more Orthologs mouse all