NTN4, Official Symbol NTN4provided by HGNC Official Full Name netrin 4provided by HGNC Primary source HGNC:HGNC:13658 See related Ensembl:ENSG00000074527 MIM:610401; AllianceGenome:HGNC:13658 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRO3091 Summary This gene encodes a member of the netrin family of proteins, which function in various biological processes including axon guidance, tumorogenesis, and angiogenesis. Netrins are laminin-related proteins that have an N-terminal laminin-type domain, epidermal growth factor-like repeat domain, and a positively charged heparin-binding domain at the C-terminus. The protein encoded by this gene is involved in processes including neurite growth and migration, angiogenesis and mural cell adhesion to endothelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] Expression Broad expression in spleen (RPKM 88.7), kidney (RPKM 62.7) and 20 other tissues See more Orthologs mouse all