CARD16, Official Symbol CARD16provided by HGNC Official Full Name caspase recruitment domain family member 16provided by HGNC Primary source HGNC:HGNC:33701 See related Ensembl:ENSG00000204397 MIM:615680; AllianceGenome:HGNC:33701 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as COP; COP1; PSEUDO-ICE; LLID-114769 Summary Enables several functions, including CARD domain binding activity; cysteine-type endopeptidase inhibitor activity; and enzyme binding activity. Involved in several processes, including negative regulation of cysteine-type endopeptidase activity; regulation of gene expression; and regulation of signal transduction. Part of protease inhibitor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 14.0), appendix (RPKM 12.0) and 23 other tissues See more Orthologs all