CCDC8, Official Symbol CCDC8provided by HGNC Official Full Name coiled-coil domain containing 8provided by HGNC Primary source HGNC:HGNC:25367 See related Ensembl:ENSG00000169515 MIM:614145; AllianceGenome:HGNC:25367 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 3M3; p90; PPP1R20 Summary This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011] Orthologs mouse all