NCOA5, Official Symbol NCOA5provided by HGNC Official Full Name nuclear receptor coactivator 5provided by HGNC Primary source HGNC:HGNC:15909 See related Ensembl:ENSG00000124160 MIM:616825; AllianceGenome:HGNC:15909 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CIA; bA465L10.6 Summary This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2017] Expression Ubiquitous expression in testis (RPKM 19.7), ovary (RPKM 15.7) and 25 other tissues See more Orthologs mouse all