NUP58, Official Symbol NUP58provided by HGNC Official Full Name nucleoporin 58provided by HGNC Primary source HGNC:HGNC:20261 See related Ensembl:ENSG00000139496 MIM:607615; AllianceGenome:HGNC:20261 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NUP45; NUPL1; PRO2463 Summary This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 26.3), thyroid (RPKM 10.4) and 24 other tissues See more Orthologs mouse all