PEX26, Official Symbol PEX26provided by HGNC Official Full Name peroxisomal biogenesis factor 26provided by HGNC Primary source HGNC:HGNC:22965 See related Ensembl:ENSG00000215193 MIM:608666; AllianceGenome:HGNC:22965 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PBD7A; PBD7B; PEX26M1T; Pex26pM1T Summary This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in colon (RPKM 17.4), small intestine (RPKM 11.2) and 25 other tissues See more Orthologs mouse all