ODAD4, Official Symbol ODAD4provided by HGNC Official Full Name outer dynein arm docking complex subunit 4provided by HGNC Primary source HGNC:HGNC:25280 See related Ensembl:ENSG00000204815 MIM:617095; AllianceGenome:HGNC:25280 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTC25 Summary This gene encodes a tetratricopeptide repeat domain-containing protein that localizes to ciliary axonmenes and plays a role in the docking of the outer dynein arm to cilia. Mutations in this gene cause severely reduced ciliary motility and the disorder CILD35 (ciliary dyskinesia,primary, 35). Primary ciliary dyskinesia is often associated with recurrent respiratory infections, immotile spermatozoa, and situs inversus; an inversion in left-right body symmetry. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017] Expression Biased expression in testis (RPKM 20.2) and lung (RPKM 1.7) See more Orthologs mouse all