DRAM2, Official Symbol DRAM2provided by HGNC Official Full Name DNA damage regulated autophagy modulator 2provided by HGNC Primary source HGNC:HGNC:28769 See related Ensembl:ENSG00000156171 MIM:613360; AllianceGenome:HGNC:28769 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CORD21; PRO180; TMEM77; WWFQ154 Summary The protein encoded by this gene binds microtubule-associated protein 1 light chain 3 and is required for autophagy. Defects in this gene are a cause of retinal dystrophy. In addition, two microRNAs (microRNA 125b-1 and microRNA 144) can bind to the mRNA of this gene and produce the disease state. [provided by RefSeq, Mar 2017] Expression Ubiquitous expression in lymph node (RPKM 29.0), spleen (RPKM 26.6) and 25 other tissues See more Orthologs mouse all