FHOD1, Official Symbol FHOD1provided by HGNC Official Full Name formin homology 2 domain containing 1provided by HGNC Primary source HGNC:HGNC:17905 See related Ensembl:ENSG00000135723 MIM:606881; AllianceGenome:HGNC:17905 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FHOS Summary This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Broad expression in spleen (RPKM 38.0), lung (RPKM 13.5) and 20 other tissues See more Orthologs mouse all