AATK, Official Symbol AATKprovided by HGNC Official Full Name apoptosis associated tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:21 See related Ensembl:ENSG00000181409 MIM:605276; AllianceGenome:HGNC:21 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LMR1; AATYK; LMTK1; p35BP; AATYK1; PPP1R77 Summary The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] Expression Biased expression in brain (RPKM 12.1), duodenum (RPKM 7.0) and 11 other tissues See more Orthologs mouse all