DERL2, Official Symbol DERL2provided by HGNC Official Full Name derlin 2provided by HGNC Primary source HGNC:HGNC:17943 See related Ensembl:ENSG00000072849 MIM:610304; AllianceGenome:HGNC:17943 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FLANa; F-LANa; CGI-101; F-LAN-1; derlin-2; DERtrin-2 Summary Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in thyroid (RPKM 9.0), testis (RPKM 7.8) and 25 other tissues See more Orthologs mouse all