CX3CR1, Official Symbol CX3CR1provided by HGNC Official Full Name C-X3-C motif chemokine receptor 1provided by HGNC Primary source HGNC:HGNC:2558 See related Ensembl:ENSG00000168329 MIM:601470; AllianceGenome:HGNC:2558 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1 Summary Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] Expression Biased expression in brain (RPKM 21.4), lung (RPKM 6.4) and 12 other tissues See more Orthologs mouse all