AP1S1, Official Symbol AP1S1provided by HGNC Official Full Name adaptor related protein complex 1 subunit sigma 1provided by HGNC Primary source HGNC:HGNC:559 See related Ensembl:ENSG00000106367 MIM:603531; AllianceGenome:HGNC:559 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AP19; EKV3; CLAPS1; MEDNIK; SIGMA1A Summary The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 52.8), colon (RPKM 23.4) and 23 other tissues See more Orthologs mouse all