LRRC2, Official Symbol LRRC2provided by HGNC Official Full Name leucine rich repeat containing 2provided by HGNC Primary source HGNC:HGNC:14676 See related Ensembl:ENSG00000163827 MIM:607180; AllianceGenome:HGNC:14676 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Sep 2011] Expression Biased expression in heart (RPKM 15.6), thyroid (RPKM 11.1) and 9 other tissues See more Orthologs mouse all