CLCA1, Official Symbol CLCA1provided by HGNC Official Full Name chloride channel accessory 1provided by HGNC Primary source HGNC:HGNC:2015 See related Ensembl:ENSG00000016490 MIM:603906; AllianceGenome:HGNC:2015 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CACC; GOB5; CACC1; CLCRG1; CaCC-1; hCLCA1; hCaCC-1 Summary This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008] Expression Biased expression in small intestine (RPKM 634.9), duodenum (RPKM 392.5) and 2 other tissues See more Orthologs mouse all