UBE2J2, Official Symbol UBE2J2provided by HGNC Official Full Name ubiquitin conjugating enzyme E2 J2provided by HGNC Primary source HGNC:HGNC:19268 See related Ensembl:ENSG00000160087 MIM:619756; AllianceGenome:HGNC:19268 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBC6; NCUBE2; NCUBE-2; PRO2121 Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 15.7), fat (RPKM 6.0) and 25 other tissues See more Orthologs mouse all