POLB, Official Symbol POLBprovided by HGNC Official Full Name DNA polymerase betaprovided by HGNC Primary source HGNC:HGNC:9174 See related Ensembl:ENSG00000070501 MIM:174760; AllianceGenome:HGNC:9174 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011] Expression Broad expression in testis (RPKM 24.2), urinary bladder (RPKM 8.5) and 24 other tissues See more Orthologs mouse all