PRSS57, Official Symbol PRSS57provided by HGNC Official Full Name serine protease 57provided by HGNC Primary source HGNC:HGNC:31397 See related Ensembl:ENSG00000185198 AllianceGenome:HGNC:31397 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NSP4; PRSSL1; UNQ782 Summary This gene encodes an arginine-specific serine protease and member of the peptidase S1 family of proteins. The encoded protein may undergo proteolytic activation before storage in azurophil granules, in neutrophil cells of the immune system. Following neutrophil activation, the protease is released into the pericellular environment, where it may play a role in defense against microbial pathogens. [provided by RefSeq, Jul 2016] Expression Restricted expression toward bone marrow (RPKM 54.0) See more Orthologs mouse all