AMBN, Official Symbol AMBNprovided by HGNC Official Full Name ameloblastinprovided by HGNC Primary source HGNC:HGNC:452 See related Ensembl:ENSG00000178522 MIM:601259; AllianceGenome:HGNC:452 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AI1F Summary This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. [provided by RefSeq, Aug 2011] Expression Low expression observed in reference dataset See more Orthologs mouse all