HOXC8, Official Symbol HOXC8provided by HGNC Official Full Name homeobox C8provided by HGNC Primary source HGNC:HGNC:5129 See related Ensembl:ENSG00000037965 MIM:142970; AllianceGenome:HGNC:5129 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX3; HOX3A Summary This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders. [provided by RefSeq, Jul 2008] Expression Biased expression in fat (RPKM 3.5), adrenal (RPKM 3.0) and 9 other tissues See more Orthologs mouse all