ROBO4, Official Symbol ROBO4provided by HGNC Official Full Name roundabout guidance receptor 4provided by HGNC Primary source HGNC:HGNC:17985 See related Ensembl:ENSG00000154133 MIM:607528; AllianceGenome:HGNC:17985 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRB; AOVD3; ECSM4 Summary Predicted to enable cell-cell adhesion mediator activity. Involved in angiogenesis and establishment of endothelial barrier. Located in extracellular exosome. Implicated in aortic valve disease 3. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in fat (RPKM 35.9), spleen (RPKM 32.4) and 17 other tissues See more Orthologs mouse all