HOXA13, Official Symbol HOXA13provided by HGNC Official Full Name homeobox A13provided by HGNC Primary source HGNC:HGNC:5102 See related Ensembl:ENSG00000106031 MIM:142959; AllianceGenome:HGNC:5102 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; HOX1J Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq, Jul 2008] Expression Biased expression in prostate (RPKM 14.7), placenta (RPKM 10.9) and 2 other tissues See more Orthologs mouse all