FEZ1, Official Symbol FEZ1provided by HGNC Official Full Name fasciculation and elongation protein zeta 1provided by HGNC Primary source HGNC:HGNC:3659 See related Ensembl:ENSG00000149557 MIM:604825; AllianceGenome:HGNC:3659 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UNC-76 Summary This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 74.3), urinary bladder (RPKM 9.7) and 4 other tissues See more Orthologs mouse all