FZD3, Official Symbol FZD3provided by HGNC Official Full Name frizzled class receptor 3provided by HGNC Primary source HGNC:HGNC:4041 See related Ensembl:ENSG00000104290 MIM:606143; AllianceGenome:HGNC:4041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fz-3 Summary This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010] Expression Broad expression in brain (RPKM 6.0), ovary (RPKM 2.6) and 18 other tissues See more Orthologs mouse all