FCRL3, Official Symbol FCRL3provided by HGNC Official Full Name Fc receptor like 3provided by HGNC Primary source HGNC:HGNC:18506 See related Ensembl:ENSG00000160856 MIM:606510; AllianceGenome:HGNC:18506 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MAIA; FCRH3; IFGP3; IRTA3; SPAP2; CD307c Summary This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Expression Biased expression in lymph node (RPKM 31.5), spleen (RPKM 20.4) and 2 other tissues See more Orthologs all