PAGE4, Official Symbol PAGE4provided by HGNC Official Full Name PAGE family member 4provided by HGNC Primary source HGNC:HGNC:4108 See related Ensembl:ENSG00000101951 MIM:300287; AllianceGenome:HGNC:4108 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JM27; JM-27; CT16.7; GAGE-9; GAGEC1; PAGE-1; PAGE-4 Summary This gene is a member of the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in prostate and prostate cancer. It is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer. The protein encoded by this gene shares sequence similarity with other GAGE/PAGE proteins, and also belongs to a family of CT (cancer-testis) antigens. The protein may play a role in benign and malignant prostate diseases. A related pseudogene is located on chromosome 7. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Restricted expression toward placenta (RPKM 272.2) See more Orthologs all