ANXA8, Official Symbol ANXA8provided by HGNC Official Full Name annexin A8provided by HGNC Primary source HGNC:HGNC:546 See related Ensembl:ENSG00000265190 MIM:602396; AllianceGenome:HGNC:546 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANX8; CH17-360D5.2 Summary This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008] Annotation information Note: There are multiple copies of ANXA8-like sequences on human chromosome 10q11. In June, 2007, the locations were re-named to correspond to the order defined by the Human Gene Nomenclature Committee (HGNC). [22 Jun 2007] Expression Biased expression in skin (RPKM 96.8), esophagus (RPKM 57.8) and 3 other tissues See more Orthologs all