UBASH3A, Official Symbol UBASH3Aprovided by HGNC Official Full Name ubiquitin associated and SH3 domain containing Aprovided by HGNC Primary source HGNC:HGNC:12462 See related Ensembl:ENSG00000160185 MIM:605736; AllianceGenome:HGNC:12462 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TULA; CLIP4; STS-2; TULA-1 Summary This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] Expression Biased expression in lymph node (RPKM 3.3), appendix (RPKM 1.9) and 12 other tissues See more Orthologs mouse all