CSTF3, Official Symbol CSTF3provided by HGNC Official Full Name cleavage stimulation factor subunit 3provided by HGNC Primary source HGNC:HGNC:2485 See related Ensembl:ENSG00000176102 MIM:600367; AllianceGenome:HGNC:2485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CSTF-77 Summary The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 12.9), lymph node (RPKM 7.3) and 25 other tissues See more Orthologs mouse all