ARF5, Official Symbol ARF5provided by HGNC Official Full Name ADP ribosylation factor 5provided by HGNC Primary source HGNC:HGNC:658 See related Ensembl:ENSG00000004059 MIM:103188; AllianceGenome:HGNC:658 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in esophagus (RPKM 84.6), skin (RPKM 63.4) and 25 other tissues See more Orthologs mouse all