GTF2H3, Official Symbol GTF2H3provided by HGNC Official Full Name general transcription factor IIH subunit 3provided by HGNC Primary source HGNC:HGNC:4657 See related Ensembl:ENSG00000111358 MIM:601750; AllianceGenome:HGNC:4657 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P34; BTF2; TFB4; TFIIH Summary This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012] Expression Ubiquitous expression in lymph node (RPKM 6.3), brain (RPKM 6.2) and 25 other tissues See more Orthologs mouse all