ASIC4, Official Symbol ASIC4provided by HGNC Official Full Name acid sensing ion channel subunit family member 4provided by HGNC Primary source HGNC:HGNC:21263 See related Ensembl:ENSG00000072182 MIM:606715; AllianceGenome:HGNC:21263 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACCN4; BNAC4 Summary This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012] Expression Biased expression in brain (RPKM 5.1), adrenal (RPKM 0.8) and 1 other tissue See more Orthologs mouse all