DHX36, Official Symbol DHX36provided by HGNC Official Full Name DEAH-box helicase 36provided by HGNC Primary source HGNC:HGNC:14410 See related Ensembl:ENSG00000174953 MIM:612767; AllianceGenome:HGNC:14410 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G4R1; RHAU; DDX36; MLEL1 Summary This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 24.2), thyroid (RPKM 15.5) and 25 other tissues See more Orthologs mouse all