DENND3, Official Symbol DENND3provided by HGNC Official Full Name DENN domain containing 3provided by HGNC Primary source HGNC:HGNC:29134 See related Ensembl:ENSG00000105339 MIM:617503; AllianceGenome:HGNC:29134 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular protein catabolic process; endosome to lysosome transport; and regulation of Rab protein signal transduction. Predicted to be located in cytosol. Predicted to be active in cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 17.0), lung (RPKM 14.2) and 23 other tissues See more Orthologs mouse all