SYP, Official Symbol SYPprovided by HGNC Official Full Name synaptophysinprovided by HGNC Primary source HGNC:HGNC:11506 See related Ensembl:ENSG00000102003 MIM:313475; AllianceGenome:HGNC:11506 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRX96; MRXSYP; XLID96 Summary This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017] Expression Biased expression in brain (RPKM 226.8) and adrenal (RPKM 21.1) See more Orthologs mouse all