BCL7A, Official Symbol BCL7Aprovided by HGNC Official Full Name BAF chromatin remodeling complex subunit BCL7Aprovided by HGNC Primary source HGNC:HGNC:1004 See related Ensembl:ENSG00000110987 MIM:601406; AllianceGenome:HGNC:1004 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCL7; SMARCJ1 Summary This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 10.8), lymph node (RPKM 10.6) and 25 other tissues See more Orthologs mouse all