ACRBP, Official Symbol ACRBPprovided by HGNC Official Full Name acrosin binding proteinprovided by HGNC Primary source HGNC:HGNC:17195 See related Ensembl:ENSG00000111644 MIM:608352; AllianceGenome:HGNC:17195 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT23; SP32; OY-TES-1 Summary The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008] Expression Restricted expression toward testis (RPKM 162.2) See more Orthologs mouse all