CDK19, Official Symbol CDK19provided by HGNC Official Full Name cyclin dependent kinase 19provided by HGNC Primary source HGNC:HGNC:19338 See related Ensembl:ENSG00000155111 MIM:614720; AllianceGenome:HGNC:19338 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDK11; DEE87; CDC2L6; EIEE87; bA346C16.3 Summary This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] Expression Broad expression in prostate (RPKM 16.5), brain (RPKM 8.7) and 23 other tissues See more Orthologs mouse all