PTGR1, Official Symbol PTGR1provided by HGNC Official Full Name prostaglandin reductase 1provided by HGNC Primary source HGNC:HGNC:18429 See related Ensembl:ENSG00000106853 MIM:601274; AllianceGenome:HGNC:18429 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR1; DIG-1; ZADH3; LTB4DH Summary This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] Expression Broad expression in liver (RPKM 118.8), small intestine (RPKM 109.3) and 18 other tissues See more Orthologs mouse all