KCTD21, Official Symbol KCTD21provided by HGNC Official Full Name potassium channel tetramerization domain containing 21provided by HGNC Primary source HGNC:HGNC:27452 See related Ensembl:ENSG00000188997 MIM:618790; AllianceGenome:HGNC:27452 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KCASH2 Summary Enables cullin family protein binding activity; histone deacetylase binding activity; and identical protein binding activity. Involved in negative regulation of smoothened signaling pathway and ubiquitin-dependent protein catabolic process. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 3.5), brain (RPKM 3.4) and 25 other tissues See more Orthologs mouse all