MAS1, Official Symbol MAS1provided by HGNC Official Full Name MAS1 proto-oncogene, G protein-coupled receptorprovided by HGNC Primary source HGNC:HGNC:6899 See related Ensembl:ENSG00000130368 MIM:165180; AllianceGenome:HGNC:6899 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MAS; MGRA Summary This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012] Orthologs mouse all