UBE2G2, Official Symbol UBE2G2provided by HGNC Official Full Name ubiquitin conjugating enzyme E2 G2provided by HGNC Primary source HGNC:HGNC:12483 See related Ensembl:ENSG00000184787 MIM:603124; AllianceGenome:HGNC:12483 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBC7 Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011] Expression Ubiquitous expression in spleen (RPKM 19.6), appendix (RPKM 19.0) and 25 other tissues See more Orthologs mouse all