MAPK11, Official Symbol MAPK11provided by HGNC Official Full Name mitogen-activated protein kinase 11provided by HGNC Primary source HGNC:HGNC:6873 See related Ensembl:ENSG00000185386 MIM:602898; AllianceGenome:HGNC:6873 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P38B; SAPK2; p38-2; PRKM11; SAPK2B; p38Beta; P38BETA2 Summary This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] Expression Ubiquitous expression in fat (RPKM 13.9), brain (RPKM 10.1) and 22 other tissues See more Orthologs mouse all