ZFP91, Official Symbol ZFP91provided by HGNC Official Full Name ZFP91 zinc finger protein, atypical E3 ubiquitin ligaseprovided by HGNC Primary source HGNC:HGNC:14983 See related Ensembl:ENSG00000186660 MIM:619289; AllianceGenome:HGNC:14983 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PZF; DSM8; DMS-8; DSM-8; FKSG11; ZFP-91; ZNF757 Summary The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2. [provided by RefSeq, Oct 2010] Expression Broad expression in testis (RPKM 63.1), bone marrow (RPKM 24.8) and 25 other tissues See more Orthologs mouse all