TYW3, Official Symbol TYW3provided by HGNC Official Full Name tRNA-yW synthesizing protein 3 homologprovided by HGNC Primary source HGNC:HGNC:24757 See related Ensembl:ENSG00000162623 MIM:611245; AllianceGenome:HGNC:24757 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1orf171 Summary Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in thyroid (RPKM 10.1), ovary (RPKM 8.9) and 25 other tissues See more Orthologs mouse all