TRIT1, Official Symbol TRIT1provided by HGNC Official Full Name tRNA isopentenyltransferase 1provided by HGNC Primary source HGNC:HGNC:20286 See related Ensembl:ENSG00000043514 MIM:617840; AllianceGenome:HGNC:20286 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IPT; GRO1; IPPT; MOD5; hGRO1; IPTase; COXPD35 Summary This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015] Expression Ubiquitous expression in thyroid (RPKM 7.3), prostate (RPKM 6.7) and 25 other tissues See more Orthologs mouse all