EIF4EBP2, Official Symbol EIF4EBP2provided by HGNC Official Full Name eukaryotic translation initiation factor 4E binding protein 2provided by HGNC Primary source HGNC:HGNC:3289 See related Ensembl:ENSG00000148730 MIM:602224; AllianceGenome:HGNC:3289 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 4EBP2; PHASII Summary This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008] Expression Ubiquitous expression in fat (RPKM 50.2), kidney (RPKM 34.8) and 25 other tissues See more Orthologs mouse all