AGFG2, Official Symbol AGFG2provided by HGNC Official Full Name ArfGAP with FG repeats 2provided by HGNC Primary source HGNC:HGNC:5177 See related Ensembl:ENSG00000106351 MIM:604019; AllianceGenome:HGNC:5177 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HRBL; RABR Summary This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013] Expression Broad expression in salivary gland (RPKM 40.8), skin (RPKM 8.2) and 21 other tissues See more Orthologs mouse all