SMPDL3B, Official Symbol SMPDL3Bprovided by HGNC Official Full Name sphingomyelin phosphodiesterase acid like 3Bprovided by HGNC Primary source HGNC:HGNC:21416 See related Ensembl:ENSG00000130768 MIM:617737; AllianceGenome:HGNC:21416 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ASML3B Summary Enables phosphoric diester hydrolase activity. Predicted to be involved in membrane lipid catabolic process; negative regulation of inflammatory response; and negative regulation of toll-like receptor signaling pathway. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in duodenum (RPKM 6.3), colon (RPKM 6.3) and 13 other tissues See more Orthologs mouse all