EDC3, Official Symbol EDC3provided by HGNC Official Full Name enhancer of mRNA decapping 3provided by HGNC Primary source HGNC:HGNC:26114 See related Ensembl:ENSG00000179151 MIM:609842; AllianceGenome:HGNC:26114 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YJDC; LSM16; MRT50; YJEFN2; hYjeF_N2-15q23 Summary This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017] Expression Ubiquitous expression in testis (RPKM 14.2), ovary (RPKM 7.5) and 25 other tissues See more Orthologs mouse all