POLR2M, Official Symbol POLR2Mprovided by HGNC Official Full Name RNA polymerase II subunit Mprovided by HGNC Primary source HGNC:HGNC:14862 See related Ensembl:ENSG00000255529 MIM:606485; AllianceGenome:HGNC:14862 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GCOM1; Gdown; Gdown1; GRINL1A Summary This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4. Readthrough transcription between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein) is represented with GeneID 145781. [provided by RefSeq, Oct 2013] Expression Ubiquitous expression in endometrium (RPKM 23.6), ovary (RPKM 17.1) and 25 other tissues See more Orthologs mouse all