HEY1, Official Symbol HEY1provided by HGNC Official Full Name hes related family bHLH transcription factor with YRPW motif 1provided by HGNC Primary source HGNC:HGNC:4880 See related Ensembl:ENSG00000164683 MIM:602953; AllianceGenome:HGNC:4880 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHF2; OAF1; HERP2; HESR1; HRT-1; NERP2; hHRT1; BHLHb31 Summary This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 32.0), lung (RPKM 10.8) and 9 other tissues See more Orthologs mouse all