GNAQ, Official Symbol GNAQprovided by HGNC Official Full Name G protein subunit alpha qprovided by HGNC Primary source HGNC:HGNC:4390 See related Ensembl:ENSG00000156052 MIM:600998; AllianceGenome:HGNC:4390 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAQ; SWS; CMAL; CMC1; G-ALPHA-q Summary This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010] Expression Ubiquitous expression in brain (RPKM 36.1), lung (RPKM 23.2) and 25 other tissues See more Orthologs mouse all