PLS1, Official Symbol PLS1provided by HGNC Official Full Name plastin 1provided by HGNC Primary source HGNC:HGNC:9090 See related Ensembl:ENSG00000120756 MIM:602734; AllianceGenome:HGNC:9090 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNA76 Summary Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010] Expression Biased expression in small intestine (RPKM 111.8), duodenum (RPKM 68.2) and 5 other tissues See more Orthologs mouse all