GRIN3A, Official Symbol GRIN3Aprovided by HGNC Official Full Name glutamate ionotropic receptor NMDA type subunit 3Aprovided by HGNC Primary source HGNC:HGNC:16767 See related Ensembl:ENSG00000198785 MIM:606650; AllianceGenome:HGNC:16767 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NR3A; GluN3A; NMDAR-L; NMDAR3A Summary This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 4.0), prostate (RPKM 0.5) and 3 other tissues See more Orthologs mouse all