USP22, Official Symbol USP22provided by HGNC Official Full Name ubiquitin specific peptidase 22provided by HGNC Primary source HGNC:HGNC:12621 See related Ensembl:ENSG00000124422 MIM:612116; AllianceGenome:HGNC:12621 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as USP3L Summary Enables enzyme binding activity; nuclear receptor coactivator activity; and thiol-dependent deubiquitinase. Contributes to H4 histone acetyltransferase activity. Involved in positive regulation of mitotic cell cycle; positive regulation of transcription, DNA-templated; and protein modification by small protein conjugation or removal. Part of SAGA complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 54.0), ovary (RPKM 38.9) and 25 other tissues See more Orthologs mouse all