PPP1R16B, Official Symbol PPP1R16Bprovided by HGNC Official Full Name protein phosphatase 1 regulatory subunit 16Bprovided by HGNC Primary source HGNC:HGNC:15850 See related Ensembl:ENSG00000101445 MIM:613275; AllianceGenome:HGNC:15850 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIMAP; ANKRD4 Summary The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015] Expression Broad expression in lymph node (RPKM 19.5), brain (RPKM 18.4) and 18 other tissues See more Orthologs mouse all