SLCO1C1, Official Symbol SLCO1C1provided by HGNC Official Full Name solute carrier organic anion transporter family member 1C1provided by HGNC Primary source HGNC:HGNC:13819 See related Ensembl:ENSG00000139155 MIM:613389; AllianceGenome:HGNC:13819 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OATP1; OATPF; OATP-F; OATP14; OATP1C1; OATPRP5; OATP-RP5; SLC21A14 Summary This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] Expression Biased expression in brain (RPKM 4.0), fat (RPKM 0.5) and 3 other tissues See more Orthologs mouse all