PPP1R17, Official Symbol PPP1R17provided by HGNC Official Full Name protein phosphatase 1 regulatory subunit 17provided by HGNC Primary source HGNC:HGNC:16973 See related Ensembl:ENSG00000106341 MIM:604088; AllianceGenome:HGNC:16973 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GSBS; C7orf16 Summary The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] Expression Biased expression in adrenal (RPKM 1.4), brain (RPKM 0.7) and 3 other tissues See more Orthologs mouse all