SMPD2, Official Symbol SMPD2provided by HGNC Official Full Name sphingomyelin phosphodiesterase 2provided by HGNC Primary source HGNC:HGNC:11121 See related Ensembl:ENSG00000135587 MIM:603498; AllianceGenome:HGNC:11121 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ISC1; NSMASE; NSMASE1 Summary This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009] Expression Broad expression in testis (RPKM 17.9), skin (RPKM 6.8) and 24 other tissues See more Orthologs mouse all