KCNQ3, Official Symbol KCNQ3provided by HGNC Official Full Name potassium voltage-gated channel subfamily Q member 3provided by HGNC Primary source HGNC:HGNC:6297 See related Ensembl:ENSG00000184156 MIM:602232; AllianceGenome:HGNC:6297 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EBN2; BFNC2; KV7.3 Summary This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014] Expression Biased expression in brain (RPKM 5.1) and adrenal (RPKM 0.4) See more Orthologs mouse all