ANAPC13, Official Symbol ANAPC13provided by HGNC Official Full Name anaphase promoting complex subunit 13provided by HGNC Primary source HGNC:HGNC:24540 See related Ensembl:ENSG00000129055 MIM:614484; AllianceGenome:HGNC:24540 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SWM1; APC13 Summary This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008] Expression Ubiquitous expression in thyroid (RPKM 36.9), kidney (RPKM 32.9) and 25 other tissues See more Orthologs mouse all