NMU, Official Symbol NMUprovided by HGNC Official Full Name neuromedin Uprovided by HGNC Primary source HGNC:HGNC:7859 See related Ensembl:ENSG00000109255 MIM:605103; AllianceGenome:HGNC:7859 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015] Expression Biased expression in esophagus (RPKM 5.6), skin (RPKM 5.5) and 6 other tissues See more Orthologs mouse all