MPLKIP, Official Symbol MPLKIPprovided by HGNC Official Full Name M-phase specific PLK1 interacting proteinprovided by HGNC Primary source HGNC:HGNC:16002 See related Ensembl:ENSG00000168303 MIM:609188; AllianceGenome:HGNC:16002 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ABHS; TTD4; ORF20; C7orf11 Summary The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy. [provided by RefSeq, Nov 2009] Expression Ubiquitous expression in liver (RPKM 18.5), kidney (RPKM 17.4) and 25 other tissues See more Orthologs mouse all