CHRNA6, Official Symbol CHRNA6provided by HGNC Official Full Name cholinergic receptor nicotinic alpha 6 subunitprovided by HGNC Primary source HGNC:HGNC:15963 See related Ensembl:ENSG00000147434 MIM:606888; AllianceGenome:HGNC:15963 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHNRA6 Summary This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010] Expression Low expression observed in reference dataset See more Orthologs mouse all