LPAR1, Official Symbol LPAR1provided by HGNC Official Full Name lysophosphatidic acid receptor 1provided by HGNC Primary source HGNC:HGNC:3166 See related Ensembl:ENSG00000198121 MIM:602282; AllianceGenome:HGNC:3166 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EDG2; LPA1; VZG1; edg-2; vzg-1; Gpcr26; Mrec1.3; rec.1.3 Summary The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene. [provided by RefSeq, Oct 2020] Expression Ubiquitous expression in brain (RPKM 14.7), placenta (RPKM 8.1) and 22 other tissues See more Orthologs mouse all