EPHB6, Official Symbol EPHB6provided by HGNC Official Full Name EPH receptor B6provided by HGNC Primary source HGNC:HGNC:3396 See related Ensembl:ENSG00000106123 MIM:602757; AllianceGenome:HGNC:3396 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEP Summary This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Biased expression in skin (RPKM 52.0), brain (RPKM 17.5) and 11 other tissues See more Orthologs mouse all