HMX2, Official Symbol HMX2provided by HGNC Official Full Name H6 family homeobox 2provided by HGNC Primary source HGNC:HGNC:5018 See related Ensembl:ENSG00000188816 MIM:600647; AllianceGenome:HGNC:5018 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H6L; Nkx5-2 Summary The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012] Expression Biased expression in kidney (RPKM 1.3) and duodenum (RPKM 0.1) See more Orthologs mouse all