AGPAT1, Official Symbol AGPAT1provided by HGNC Official Full Name 1-acylglycerol-3-phosphate O-acyltransferase 1provided by HGNC Primary source HGNC:HGNC:324 See related Ensembl:ENSG00000204310 MIM:603099; AllianceGenome:HGNC:324 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G15; LPAATA; LPLAT1; 1-AGPAT1; LPAAT-alpha Summary This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 25.5), brain (RPKM 21.6) and 25 other tissues See more Orthologs mouse all