UBR2, Official Symbol UBR2provided by HGNC Official Full Name ubiquitin protein ligase E3 component n-recognin 2provided by HGNC Primary source HGNC:HGNC:21289 See related Ensembl:ENSG00000024048 MIM:609134; AllianceGenome:HGNC:21289 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C6orf133; bA49A4.1; dJ242G1.1; dJ392M17.3 Summary Enables leucine binding activity. Involved in cellular response to leucine and negative regulation of TOR signaling. Predicted to be located in cytosol. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Predicted to colocalize with chromatin. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 7.8), spleen (RPKM 6.8) and 25 other tissues See more Orthologs mouse all