MYH7B, Official Symbol MYH7Bprovided by HGNC Official Full Name myosin heavy chain 7Bprovided by HGNC Primary source HGNC:HGNC:15906 See related Ensembl:ENSG00000078814 MIM:609928; AllianceGenome:HGNC:15906 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MHC14; MYH14; lncMYH7b Summary The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010] Expression Biased expression in heart (RPKM 13.9), testis (RPKM 3.7) and 2 other tissues See more Orthologs mouse all