FRS2, Official Symbol FRS2provided by HGNC Official Full Name fibroblast growth factor receptor substrate 2provided by HGNC Primary source HGNC:HGNC:16971 See related Ensembl:ENSG00000166225 MIM:607743; AllianceGenome:HGNC:16971 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SNT; SNT1; FRS1A; FRS2A; SNT-1; FRS2alpha Summary Enables fibroblast growth factor receptor binding activity and neurotrophin TRKA receptor binding activity. Involved in negative regulation of cardiac muscle cell differentiation. Acts upstream of or within fibroblast growth factor receptor signaling pathway. Located in adherens junction. Biomarker of renal cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 6.6), endometrium (RPKM 6.6) and 25 other tissues See more Orthologs mouse all