PDE7A, Official Symbol PDE7Aprovided by HGNC Official Full Name phosphodiesterase 7Aprovided by HGNC Primary source HGNC:HGNC:8791 See related Ensembl:ENSG00000205268 MIM:171885; AllianceGenome:HGNC:8791 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HCP1; PDE7 Summary The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011] Expression Broad expression in lymph node (RPKM 14.6), appendix (RPKM 7.7) and 23 other tissues See more Orthologs mouse all