CH25H, Official Symbol CH25Hprovided by HGNC Official Full Name cholesterol 25-hydroxylaseprovided by HGNC Primary source HGNC:HGNC:1907 See related Ensembl:ENSG00000138135 MIM:604551; AllianceGenome:HGNC:1907 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C25H Summary This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. [provided by RefSeq, Jul 2008] Orthologs mouse all