ARHGEF28, Official Symbol ARHGEF28provided by HGNC Official Full Name Rho guanine nucleotide exchange factor 28provided by HGNC Primary source HGNC:HGNC:30322 See related Ensembl:ENSG00000214944 MIM:612790; AllianceGenome:HGNC:30322 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIP2; RGNEF; p190RHOGEF Summary This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010] Expression Broad expression in kidney (RPKM 8.5), thyroid (RPKM 7.2) and 21 other tissues See more Orthologs mouse all