RRM1, Official Symbol RRM1provided by HGNC Official Full Name ribonucleotide reductase catalytic subunit M1provided by HGNC Primary source HGNC:HGNC:10451 See related Ensembl:ENSG00000167325 MIM:180410; AllianceGenome:HGNC:10451 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as R1; RR1; RIR1 Summary This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in skin (RPKM 18.5), lymph node (RPKM 18.3) and 25 other tissues See more Orthologs mouse all