RETN, Official Symbol RETNprovided by HGNC Official Full Name resistinprovided by HGNC Primary source HGNC:HGNC:20389 See related Ensembl:ENSG00000104918 MIM:605565; AllianceGenome:HGNC:20389 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADSF; RENT; RSTN; XCP1; FIZZ3; RETN1 Summary This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. The encoded protein also has an antimicrobial role in skin, displaying antibacterial activity against both Gram positive and Gram negative bacteria. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2020] Expression Biased expression in bone marrow (RPKM 57.7) and lung (RPKM 6.4) See more Orthologs mouse all