COQ8A, Official Symbol COQ8Aprovided by HGNC Official Full Name coenzyme Q8Aprovided by HGNC Primary source HGNC:HGNC:16812 See related Ensembl:ENSG00000163050 MIM:606980; AllianceGenome:HGNC:16812 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as COQ8; ADCK3; ARCA2; CABC1; SCAR9; COQ10D4 Summary This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 53.1), adrenal (RPKM 33.1) and 25 other tissues See more Orthologs mouse all