RASGRP3, Official Symbol RASGRP3provided by HGNC Official Full Name RAS guanyl releasing protein 3provided by HGNC Primary source HGNC:HGNC:14545 See related Ensembl:ENSG00000152689 MIM:609531; AllianceGenome:HGNC:14545 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GRP3 Summary The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017] Expression Broad expression in lymph node (RPKM 8.7), appendix (RPKM 6.4) and 22 other tissues See more Orthologs mouse all