CLDN15, Official Symbol CLDN15provided by HGNC Official Full Name claudin 15provided by HGNC Primary source HGNC:HGNC:2036 See related Ensembl:ENSG00000106404 MIM:615778; AllianceGenome:HGNC:2036 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010] Expression Biased expression in duodenum (RPKM 65.8), small intestine (RPKM 50.2) and 8 other tissues See more Orthologs mouse all