VKORC1L1, Official Symbol VKORC1L1provided by HGNC Official Full Name vitamin K epoxide reductase complex subunit 1 like 1provided by HGNC Primary source HGNC:HGNC:21492 See related Ensembl:ENSG00000196715 MIM:608838; AllianceGenome:HGNC:21492 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes an enzyme important in the vitamin K cycle, which is involved in the carboxylation of glutamate residues present in vitamin K-dependent proteins. The encoded enzyme catalyzes the de-epoxidation of vitamin K 2,3-epoxide. Oxidative stress may upregulate expression of this gene and the encoded protein may protect cells and membrane proteins form oxidative damage. This gene and a related gene (Gene ID: 79001) may have arisen by gene duplication of an ancestral gene. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in fat (RPKM 25.2), lung (RPKM 7.7) and 23 other tissues See more Orthologs mouse all