HMOX1, Official Symbol HMOX1provided by HGNC Official Full Name heme oxygenase 1provided by HGNC Primary source HGNC:HGNC:5013 See related Ensembl:ENSG00000100292 MIM:141250; AllianceGenome:HGNC:5013 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HO-1; HSP32; HMOX1D; bK286B10 Summary Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008] Expression Broad expression in spleen (RPKM 208.2), ovary (RPKM 68.8) and 17 other tissues See more Orthologs mouse all