F2RL2, Official Symbol F2RL2provided by HGNC Official Full Name coagulation factor II thrombin receptor like 2provided by HGNC Primary source HGNC:HGNC:3539 See related Ensembl:ENSG00000164220 MIM:601919; AllianceGenome:HGNC:3539 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAR3; PAR-3 Summary This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012] Expression Biased expression in gall bladder (RPKM 4.3), endometrium (RPKM 1.5) and 10 other tissues See more Orthologs mouse all