CELSR3, Official Symbol CELSR3provided by HGNC Official Full Name cadherin EGF LAG seven-pass G-type receptor 3provided by HGNC Primary source HGNC:HGNC:3230 See related Ensembl:ENSG00000008300 MIM:604264; AllianceGenome:HGNC:3230 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FMI1; EGFL1; HFMI1; MEGF2; ADGRC3; CDHF11; RESDA1 Summary This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013] Expression Broad expression in brain (RPKM 3.0), testis (RPKM 2.3) and 17 other tissues See more Orthologs mouse all