PIGR, Official Symbol PIGRprovided by HGNC Official Full Name polymeric immunoglobulin receptorprovided by HGNC Primary source HGNC:HGNC:8968 See related Ensembl:ENSG00000162896 MIM:173880; AllianceGenome:HGNC:8968 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009] Expression Biased expression in duodenum (RPKM 1246.3), colon (RPKM 1042.2) and 5 other tissues See more Orthologs mouse all