GABRE, Official Symbol GABREprovided by HGNC Official Full Name gamma-aminobutyric acid type A receptor subunit epsilonprovided by HGNC Primary source HGNC:HGNC:4085 See related Ensembl:ENSG00000102287 MIM:300093; AllianceGenome:HGNC:4085 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008] Expression Broad expression in skin (RPKM 13.6), fat (RPKM 13.4) and 17 other tissues See more Orthologs mouse all