SCARF1, Official Symbol SCARF1provided by HGNC Official Full Name scavenger receptor class F member 1provided by HGNC Primary source HGNC:HGNC:16820 See related Ensembl:ENSG00000074660 MIM:607873; AllianceGenome:HGNC:16820 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SREC; SREC1; SREC-I Summary The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] Expression Broad expression in spleen (RPKM 18.4), lung (RPKM 9.9) and 22 other tissues See more Orthologs mouse all