XPO6, Official Symbol XPO6provided by HGNC Official Full Name exportin 6provided by HGNC Primary source HGNC:HGNC:19733 See related Ensembl:ENSG00000169180 MIM:608411; AllianceGenome:HGNC:19733 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EXP6; RANBP20 Summary The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] Expression Ubiquitous expression in testis (RPKM 30.3), spleen (RPKM 24.2) and 25 other tissues See more Orthologs mouse all