PIEZO1, Official Symbol PIEZO1provided by HGNC Official Full Name piezo type mechanosensitive ion channel component 1provided by HGNC Primary source HGNC:HGNC:28993 See related Ensembl:ENSG00000103335 MIM:611184; AllianceGenome:HGNC:28993 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ER; DHS; Mib; LMPH3; FAM38A; LMPHM6 Summary The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis. [provided by RefSeq, Jul 2015] Expression Ubiquitous expression in fat (RPKM 30.4), lung (RPKM 14.8) and 24 other tissues See more Orthologs mouse all