CRBN, Official Symbol CRBNprovided by HGNC Official Full Name cereblonprovided by HGNC Primary source HGNC:HGNC:30185 See related Ensembl:ENSG00000113851 MIM:609262; AllianceGenome:HGNC:30185 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRT2; MRT2A Summary This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] Expression Ubiquitous expression in testis (RPKM 17.6), brain (RPKM 16.5) and 25 other tissues See more Orthologs mouse all