S100A2, Official Symbol S100A2provided by HGNC Official Full Name S100 calcium binding protein A2provided by HGNC Primary source HGNC:HGNC:10492 See related Ensembl:ENSG00000196754 MIM:176993; AllianceGenome:HGNC:10492 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAN19; S100L Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008] Expression Biased expression in esophagus (RPKM 199.3), urinary bladder (RPKM 56.6) and 2 other tissues See more Orthologs all