PRKAR1B, Official Symbol PRKAR1Bprovided by HGNC Official Full Name protein kinase cAMP-dependent type I regulatory subunit betaprovided by HGNC Primary source HGNC:HGNC:9390 See related Ensembl:ENSG00000188191 MIM:176911; AllianceGenome:HGNC:9390 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MASNS; PRKAR1 Summary The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2015] Expression Biased expression in brain (RPKM 53.5), ovary (RPKM 6.9) and 11 other tissues See more Orthologs mouse all