PPP2CA, Official Symbol PPP2CAprovided by HGNC Official Full Name protein phosphatase 2 catalytic subunit alphaprovided by HGNC Primary source HGNC:HGNC:9299 See related Ensembl:ENSG00000113575 MIM:176915; AllianceGenome:HGNC:9299 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HJS3; RP-C; PP2Ac; PP2CA; NEDLBA; PP2Calpha Summary This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 63.8), bone marrow (RPKM 57.1) and 25 other tissues See more Orthologs mouse all