LPP, Official Symbol LPPprovided by HGNC Official Full Name LIM domain containing preferred translocation partner in lipomaprovided by HGNC Primary source HGNC:HGNC:6679 See related Ensembl:ENSG00000145012 MIM:600700; AllianceGenome:HGNC:6679 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in endometrium (RPKM 14.7), esophagus (RPKM 14.3) and 24 other tissues See more Orthologs mouse all