NFIL3, Official Symbol NFIL3provided by HGNC Official Full Name nuclear factor, interleukin 3 regulatedprovided by HGNC Primary source HGNC:HGNC:7787 See related Ensembl:ENSG00000165030 MIM:605327; AllianceGenome:HGNC:7787 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as E4BP4; IL3BP1; NFIL3A; NF-IL3A Summary The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014] Expression Broad expression in bone marrow (RPKM 59.6), adrenal (RPKM 37.4) and 23 other tissues See more Orthologs mouse all