PARG, Official Symbol PARGprovided by HGNC Official Full Name poly(ADP-ribose) glycohydrolaseprovided by HGNC Primary source HGNC:HGNC:8605 See related Ensembl:ENSG00000227345 MIM:603501; AllianceGenome:HGNC:8605 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PARG99 Summary Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015] Expression Ubiquitous expression in kidney (RPKM 6.5), testis (RPKM 6.1) and 25 other tissues See more Orthologs mouse all