ONECUT1, Official Symbol ONECUT1provided by HGNC Official Full Name one cut homeobox 1provided by HGNC Primary source HGNC:HGNC:8138 See related Ensembl:ENSG00000169856 MIM:604164; AllianceGenome:HGNC:8138 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNF6; HNF-6; HNF6A Summary This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] Expression Biased expression in liver (RPKM 2.0), gall bladder (RPKM 1.7) and 2 other tissues See more Orthologs mouse all