ENDOG, Official Symbol ENDOGprovided by HGNC Official Full Name endonuclease Gprovided by HGNC Primary source HGNC:HGNC:3346 See related Ensembl:ENSG00000167136 MIM:600440; AllianceGenome:HGNC:3346 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 10.6), prostate (RPKM 9.4) and 25 other tissues See more Orthologs mouse all