OTUD7B, Official Symbol OTUD7Bprovided by HGNC Official Full Name OTU deubiquitinase 7Bprovided by HGNC Primary source HGNC:HGNC:16683 See related Ensembl:ENSG00000264522 MIM:611748; AllianceGenome:HGNC:16683 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZA20D1; CEZANNE Summary Enables Lys48-specific deubiquitinase activity and thiol-dependent deubiquitinase. Involved in several processes, including negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of macromolecule metabolic process; and protein deubiquitination. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 4.7), testis (RPKM 4.3) and 25 other tissues See more Orthologs mouse all