NCR3, Official Symbol NCR3provided by HGNC Official Full Name natural cytotoxicity triggering receptor 3provided by HGNC Primary source HGNC:HGNC:19077 See related Ensembl:ENSG00000204475 MIM:611550; AllianceGenome:HGNC:19077 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 1C7; MALS; CD337; LY117; NKp30 Summary The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] Expression Broad expression in lymph node (RPKM 5.8), spleen (RPKM 4.7) and 18 other tissues See more Orthologs all