OS9, Official Symbol OS9provided by HGNC Official Full Name OS9 endoplasmic reticulum lectinprovided by HGNC Primary source HGNC:HGNC:16994 See related Ensembl:ENSG00000135506 MIM:609677; AllianceGenome:HGNC:16994 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OS-9; ERLEC2 Summary This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in colon (RPKM 82.8), thyroid (RPKM 81.3) and 25 other tissues See more Orthologs mouse all