UBE2I, Official Symbol UBE2Iprovided by HGNC Official Full Name ubiquitin conjugating enzyme E2 Iprovided by HGNC Primary source HGNC:HGNC:12485 See related Ensembl:ENSG00000103275 MIM:601661; AllianceGenome:HGNC:12485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P18; UBC9; C358B7.1 Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 23.2), endometrium (RPKM 17.8) and 25 other tissues See more Orthologs mouse all