PPP4R1, Official Symbol PPP4R1provided by HGNC Official Full Name protein phosphatase 4 regulatory subunit 1provided by HGNC Primary source HGNC:HGNC:9320 See related Ensembl:ENSG00000154845 MIM:604908; AllianceGenome:HGNC:9320 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MEG1; PP4R1; PP4(Rmeg) Summary This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] Expression Ubiquitous expression in esophagus (RPKM 39.0), testis (RPKM 25.5) and 25 other tissues See more Orthologs mouse all