GALNT12, Official Symbol GALNT12provided by HGNC Official Full Name polypeptide N-acetylgalactosaminyltransferase 12provided by HGNC Primary source HGNC:HGNC:19877 See related Ensembl:ENSG00000119514 MIM:610290; AllianceGenome:HGNC:19877 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRCS1; GalNAc-T12 Summary This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.[provided by RefSeq, Mar 2011] Expression Biased expression in colon (RPKM 24.5), stomach (RPKM 17.8) and 12 other tissues See more Orthologs mouse all