AARS2, Official Symbol AARS2provided by HGNC Official Full Name alanyl-tRNA synthetase 2, mitochondrialprovided by HGNC Primary source HGNC:HGNC:21022 See related Ensembl:ENSG00000124608 MIM:612035; AllianceGenome:HGNC:21022 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AARSL; LKENP; COXPD8; MTALARS; MT-ALARS Summary The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011] Expression Ubiquitous expression in small intestine (RPKM 2.7), ovary (RPKM 2.7) and 25 other tissues See more Orthologs mouse all