EIF3G, Official Symbol EIF3Gprovided by HGNC Official Full Name eukaryotic translation initiation factor 3 subunit Gprovided by HGNC Primary source HGNC:HGNC:3274 See related Ensembl:ENSG00000130811 MIM:603913; AllianceGenome:HGNC:3274 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EIF3S4; EIF3-P42; eIF3-p44; eIF3-delta Summary This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in ovary (RPKM 90.1), testis (RPKM 63.4) and 25 other tissues See more Orthologs mouse all