CCL26, Official Symbol CCL26provided by HGNC Official Full Name C-C motif chemokine ligand 26provided by HGNC Primary source HGNC:HGNC:10625 See related Ensembl:ENSG00000006606 MIM:604697; AllianceGenome:HGNC:10625 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha Summary This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2020] Expression Broad expression in ovary (RPKM 2.0), adrenal (RPKM 0.7) and 14 other tissues See more Orthologs mouse all