LINC-ROR, Official Symbol LINC-RORprovided by HGNC Official Full Name long intergenic non-protein coding RNA, regulator of reprogrammingprovided by HGNC Primary source HGNC:HGNC:43773 See related Ensembl:ENSG00000258609 MIM:615173; AllianceGenome:HGNC:43773 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ROR; lincRNA-RoR; lincRNA-ST8SIA3 Summary This gene produces a long non-coding RNA that regulates the reprogramming of pluripotent stem cells. This RNA suppresses induction of tumor protein p53 after DNA damage. It is thought to act as a sponge for microRNAs that regulate stem cell factors POU class 5 homeobox 1, Nanog, and SRY-box 2. This RNA may also have a extracellular role in modulating response to hypoxia in hepatocellular cancer cells. Expression of this transcript is associated with tumor progression and epithelial to mesenchymal transition and metastasis. [provided by RefSeq, Dec 2017] Expression Low expression observed in reference dataset See more