EIF4ENIF1, Official Symbol EIF4ENIF1provided by HGNC Official Full Name eukaryotic translation initiation factor 4E nuclear import factor 1provided by HGNC Primary source HGNC:HGNC:16687 See related Ensembl:ENSG00000184708 MIM:607445; AllianceGenome:HGNC:16687 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 4E-T; Clast4 Summary The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] Expression Broad expression in testis (RPKM 19.7), brain (RPKM 7.2) and 25 other tissues See more Orthologs mouse all