IGF2, Official Symbol IGF2provided by HGNC Official Full Name insulin like growth factor 2provided by HGNC Primary source HGNC:HGNC:5466 See related Ensembl:ENSG00000167244 MIM:147470; AllianceGenome:HGNC:5466 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GRDF; SRS3; IGF-II; PP9974; C11orf43 Summary This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] Expression Biased expression in placenta (RPKM 1052.5) and liver (RPKM 86.0) See more Orthologs mouse all