PPP2R3B, Official Symbol PPP2R3Bprovided by HGNC Official Full Name protein phosphatase 2 regulatory subunit B''betaprovided by HGNC Primary source HGNC:HGNC:13417 See related Ensembl:ENSG00000167393 Ensembl:ENSG00000292327 MIM:300339; AllianceGenome:HGNC:13417 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PR48; PR70; NYREN8; PPP2R3L; PPP2R3LY Summary Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010] Expression Broad expression in heart (RPKM 9.0), testis (RPKM 5.0) and 23 other tissues See more Orthologs all