IRX1, Official Symbol IRX1provided by HGNC Official Full Name iroquois homeobox 1provided by HGNC Primary source HGNC:HGNC:14358 See related Ensembl:ENSG00000170549 MIM:606197; AllianceGenome:HGNC:14358 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IRX-5; IRXA1 Summary This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011] Expression Biased expression in kidney (RPKM 2.5), salivary gland (RPKM 1.1) and 4 other tissues See more Orthologs mouse all