TRAIP, Official Symbol TRAIPprovided by HGNC Official Full Name TRAF interacting proteinprovided by HGNC Primary source HGNC:HGNC:30764 See related Ensembl:ENSG00000183763 MIM:605958; AllianceGenome:HGNC:30764 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRIP; SCKL9; RNF206 Summary This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 4.0), bone marrow (RPKM 2.3) and 23 other tissues See more Orthologs mouse all