DNAH6, Official Symbol DNAH6provided by HGNC Official Full Name dynein axonemal heavy chain 6provided by HGNC Primary source HGNC:HGNC:2951 See related Ensembl:ENSG00000115423 MIM:603336; AllianceGenome:HGNC:2951 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HL2; HL-2; DNHL1; Dnahc6 Summary This gene belongs to the dynein family, whose members encode large proteins that are constituents of the microtubule-associated motor protein complex. This complex is composed of dynein heavy, intermediate and light chains, which can be axonemal or cytoplasmic. This protein is an axonemal dynein heavy chain. It is involved in producing force for ciliary beating by using energy from ATP hydrolysis. Mutations in this gene may cause primary ciliary dyskinesia (PCD) as well as heterotaxy. [provided by RefSeq, Jun 2016] Expression Biased expression in testis (RPKM 1.8), thyroid (RPKM 0.7) and 11 other tissues See more Orthologs mouse all