POP1, Official Symbol POP1provided by HGNC Official Full Name POP1 homolog, ribonuclease P/MRP subunitprovided by HGNC Primary source HGNC:HGNC:30129 See related Ensembl:ENSG00000104356 MIM:602486; AllianceGenome:HGNC:30129 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANXD2 Summary This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] Expression Ubiquitous expression in testis (RPKM 2.0), appendix (RPKM 1.8) and 25 other tissues See more Orthologs mouse all