EPHA7, Official Symbol EPHA7provided by HGNC Official Full Name EPH receptor A7provided by HGNC Primary source HGNC:HGNC:3390 See related Ensembl:ENSG00000135333 MIM:602190; AllianceGenome:HGNC:3390 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EHK3; EK11; EHK-3; HEK11 Summary This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] Expression Broad expression in prostate (RPKM 3.4), kidney (RPKM 2.8) and 16 other tissues See more Orthologs mouse all