ABRAXAS2, Official Symbol ABRAXAS2provided by HGNC Official Full Name abraxas 2, BRISC complex subunitprovided by HGNC Primary source HGNC:HGNC:28975 See related Ensembl:ENSG00000165660 MIM:611144; AllianceGenome:HGNC:28975 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ABRO1; FAM175B; KIAA0157 Summary Enables microtubule binding activity and polyubiquitin modification-dependent protein binding activity. Involved in several processes, including mitotic spindle assembly; protein K63-linked deubiquitination; and response to ischemia. Located in cytoplasm. Part of BRISC complex. Colocalizes with microtubule minus-end; midbody; and spindle pole centrosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 8.5), lymph node (RPKM 6.8) and 25 other tissues See more Orthologs mouse all