ARHGAP22, Official Symbol ARHGAP22provided by HGNC Official Full Name Rho GTPase activating protein 22provided by HGNC Primary source HGNC:HGNC:30320 See related Ensembl:ENSG00000128805 MIM:610585; AllianceGenome:HGNC:30320 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RhoGAP2; RhoGap22 Summary This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Low expression observed in reference dataset See more Orthologs mouse all