MST1, Official Symbol MST1provided by HGNC Official Full Name macrophage stimulating 1provided by HGNC Primary source HGNC:HGNC:7380 See related Ensembl:ENSG00000173531 MIM:142408; AllianceGenome:HGNC:7380 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MSP; HGFL; NF15S2; D3F15S2; DNF15S2 Summary The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq, Jan 2010] Annotation information Note: MST1 (Gene ID: 4485) and STK4 (Gene ID: 6789) share the MST1 symbol/alias in common. MST1 is a widely used alternative name for serine/threonine kinase 4 (STK4), which can be confused with the official symbol for macrophage stimulating 1 (MST1). [01 Jun 2018] Expression Biased expression in liver (RPKM 45.2), duodenum (RPKM 24.6) and 13 other tissues See more Orthologs mouse all