PRIM1, Official Symbol PRIM1provided by HGNC Official Full Name DNA primase subunit 1provided by HGNC Primary source HGNC:HGNC:9369 See related Ensembl:ENSG00000198056 MIM:176635; AllianceGenome:HGNC:9369 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p49; PDIL Summary The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008] Expression Broad expression in bone marrow (RPKM 10.3), testis (RPKM 9.4) and 25 other tissues See more Orthologs mouse all