INPP5K, Official Symbol INPP5Kprovided by HGNC Official Full Name inositol polyphosphate-5-phosphatase Kprovided by HGNC Primary source HGNC:HGNC:33882 See related Ensembl:ENSG00000132376 MIM:607875; AllianceGenome:HGNC:33882 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PPS; SKIP; MDCCAID Summary This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008] Expression Ubiquitous expression in fat (RPKM 17.9), lung (RPKM 14.5) and 25 other tissues See more Orthologs mouse all