CASC2, Official Symbol CASC2provided by HGNC Official Full Name cancer susceptibility 2provided by HGNC Primary source HGNC:HGNC:22933 See related Ensembl:ENSG00000177640 MIM:608598; AllianceGenome:HGNC:22933 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C10orf5 Summary Involved in defense response to tumor cell; negative regulation of MAPK cascade; and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 1.0), brain (RPKM 1.0) and 22 other tissues See more