PPP6R2, Official Symbol PPP6R2provided by HGNC Official Full Name protein phosphatase 6 regulatory subunit 2provided by HGNC Primary source HGNC:HGNC:19253 See related Ensembl:ENSG00000100239 MIM:610877; AllianceGenome:HGNC:19253 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP6R2; SAPS2; SAP190; KIAA0685 Summary The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment. [provided by RefSeq, May 2017] Expression Ubiquitous expression in testis (RPKM 24.1), brain (RPKM 12.1) and 25 other tissues See more Orthologs mouse all