TMPRSS13, Official Symbol TMPRSS13provided by HGNC Official Full Name transmembrane serine protease 13provided by HGNC Primary source HGNC:HGNC:29808 See related Ensembl:ENSG00000137747 MIM:610050; AllianceGenome:HGNC:29808 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MSP; MSPL; MSPS; TMPRSS11 Summary This gene encodes a member of the type II transmembrane serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. This protein facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. [provided by RefSeq, Aug 2021] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in SARS-CoV-2 infection. Expression Biased expression in skin (RPKM 9.7), esophagus (RPKM 3.1) and 4 other tissues See more Orthologs mouse all