SPRED3, Official Symbol SPRED3provided by HGNC Official Full Name sprouty related EVH1 domain containing 3provided by HGNC Primary source HGNC:HGNC:31041 See related Ensembl:ENSG00000188766 MIM:609293; AllianceGenome:HGNC:31041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Eve-3; spred-3 Summary This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] Expression Broad expression in brain (RPKM 1.8), duodenum (RPKM 0.4) and 14 other tissues See more Orthologs mouse all