EHD1, Official Symbol EHD1provided by HGNC Official Full Name EH domain containing 1provided by HGNC Primary source HGNC:HGNC:3242 See related Ensembl:ENSG00000110047 MIM:605888; AllianceGenome:HGNC:3242 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAST; PAST1; H-PAST; HPAST1 Summary This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013] Expression Broad expression in bone marrow (RPKM 39.6), testis (RPKM 32.1) and 24 other tissues See more Orthologs mouse all