CRTAC1, Official Symbol CRTAC1provided by HGNC Official Full Name cartilage acidic protein 1provided by HGNC Primary source HGNC:HGNC:14882 See related Ensembl:ENSG00000095713 MIM:606276; AllianceGenome:HGNC:14882 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ASPIC; CEP68; LOTUS; ASPIC1; CEP-68 Summary This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] Expression Biased expression in lung (RPKM 23.3), brain (RPKM 10.1) and 5 other tissues See more Orthologs mouse all