CLCN6, Official Symbol CLCN6provided by HGNC Official Full Name chloride voltage-gated channel 6provided by HGNC Primary source HGNC:HGNC:2024 See related Ensembl:ENSG00000011021 MIM:602726; AllianceGenome:HGNC:2024 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLC-6; CONRIBA Summary This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012] Expression Ubiquitous expression in brain (RPKM 13.0), testis (RPKM 10.2) and 24 other tissues See more Orthologs mouse all