TM4SF1, Official Symbol TM4SF1provided by HGNC Official Full Name transmembrane 4 L six family member 1provided by HGNC Primary source HGNC:HGNC:11853 See related Ensembl:ENSG00000169908 MIM:191155; AllianceGenome:HGNC:11853 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as L6; H-L6; M3S1; TAAL6 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008] Expression Broad expression in gall bladder (RPKM 142.0), lung (RPKM 138.0) and 24 other tissues See more Orthologs mouse all