ANO6, Official Symbol ANO6provided by HGNC Official Full Name anoctamin 6provided by HGNC Primary source HGNC:HGNC:25240 See related Ensembl:ENSG00000177119 MIM:608663; AllianceGenome:HGNC:25240 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCTS; BDPLT7; TMEM16F Summary This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011] Expression Ubiquitous expression in fat (RPKM 53.4), ovary (RPKM 24.6) and 25 other tissues See more Orthologs mouse all