ZNF148, Official Symbol ZNF148provided by HGNC Official Full Name zinc finger protein 148provided by HGNC Primary source HGNC:HGNC:12933 See related Ensembl:ENSG00000163848 MIM:601897; AllianceGenome:HGNC:12933 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BERF-1; BFCOL1; GDACCF; ZBP-89; ZFP148; pHZ-52; HT-BETA Summary The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. [provided by RefSeq, Feb 2017] Expression Ubiquitous expression in thyroid (RPKM 14.7), ovary (RPKM 6.1) and 25 other tissues See more Orthologs mouse all