PPAN, Official Symbol PPANprovided by HGNC Official Full Name peter pan homologprovided by HGNC Primary source HGNC:HGNC:9227 See related Ensembl:ENSG00000130810 MIM:607793; AllianceGenome:HGNC:9227 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SSF; SSF1; SSF2; BXDC3; SSF-1 Summary The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. [provided by RefSeq, Nov 2010] Expression Ubiquitous expression in appendix (RPKM 9.7), spleen (RPKM 9.5) and 25 other tissues See more Orthologs mouse all