ADK, Official Symbol ADKprovided by HGNC Official Full Name adenosine kinaseprovided by HGNC Primary source HGNC:HGNC:257 See related Ensembl:ENSG00000156110 MIM:102750; AllianceGenome:HGNC:257 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AK Summary This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] Expression Ubiquitous expression in liver (RPKM 10.9), thyroid (RPKM 8.6) and 25 other tissues See more Orthologs mouse all