PLA2G15, Official Symbol PLA2G15provided by HGNC Official Full Name phospholipase A2 group XVprovided by HGNC Primary source HGNC:HGNC:17163 See related Ensembl:ENSG00000103066 MIM:609362; AllianceGenome:HGNC:17163 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACS; LLPL; LPLA2; LYPLA3; GXVPLA2 Summary Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in placenta (RPKM 17.1), heart (RPKM 11.8) and 25 other tissues See more Orthologs mouse all