SRGAP2, Official Symbol SRGAP2provided by HGNC Official Full Name SLIT-ROBO Rho GTPase activating protein 2provided by HGNC Primary source HGNC:HGNC:19751 See related Ensembl:ENSG00000266028 MIM:606524; AllianceGenome:HGNC:19751 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FNBP2; SRGAP3; SRGAP2A; ARHGAP34 Summary This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in skin (RPKM 12.4), spleen (RPKM 10.1) and 23 other tissues See more Orthologs mouse all