LRRC8B, Official Symbol LRRC8Bprovided by HGNC Official Full Name leucine rich repeat containing 8 VRAC subunit Bprovided by HGNC Primary source HGNC:HGNC:30692 See related Ensembl:ENSG00000197147 MIM:612888; AllianceGenome:HGNC:30692 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TALRRP; TA-LRRP Summary Contributes to volume-sensitive anion channel activity. Involved in anion transmembrane transport. Located in cytoplasm and plasma membrane. Is integral component of plasma membrane. Part of ion channel complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 8.6), adrenal (RPKM 5.3) and 25 other tissues See more Orthologs mouse all