GP2, Official Symbol GP2provided by HGNC Official Full Name glycoprotein 2provided by HGNC Primary source HGNC:HGNC:4441 See related Ensembl:ENSG00000169347 MIM:602977; AllianceGenome:HGNC:4441 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZAP75 Summary This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Expression Restricted expression toward pancreas (RPKM 2558.6) See more Orthologs mouse all