RHOU, Official Symbol RHOUprovided by HGNC Official Full Name ras homolog family member Uprovided by HGNC Primary source HGNC:HGNC:17794 See related Ensembl:ENSG00000116574 MIM:606366; AllianceGenome:HGNC:17794 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHU; G28K; WRCH1; hG28K; CDC42L1 Summary This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011] Expression Ubiquitous expression in brain (RPKM 24.2), small intestine (RPKM 22.4) and 25 other tissues See more Orthologs mouse all