MEF2A, Official Symbol MEF2Aprovided by HGNC Official Full Name myocyte enhancer factor 2Aprovided by HGNC Primary source HGNC:HGNC:6993 See related Ensembl:ENSG00000068305 MIM:600660; AllianceGenome:HGNC:6993 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as mef2; ADCAD1; RSRFC4; RSRFC9 Summary The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010] Expression Ubiquitous expression in heart (RPKM 14.6), brain (RPKM 12.2) and 25 other tissues See more Orthologs mouse all