KCNB1, Official Symbol KCNB1provided by HGNC Official Full Name potassium voltage-gated channel subfamily B member 1provided by HGNC Primary source HGNC:HGNC:6231 See related Ensembl:ENSG00000158445 MIM:600397; AllianceGenome:HGNC:6231 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DRK1; DEE26; Kv2.1 Summary Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 9.2), fat (RPKM 8.5) and 6 other tissues See more Orthologs mouse all