SNCB, Official Symbol SNCBprovided by HGNC Official Full Name synuclein betaprovided by HGNC Primary source HGNC:HGNC:11140 See related Ensembl:ENSG00000074317 MIM:602569; AllianceGenome:HGNC:11140 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Restricted expression toward brain (RPKM 60.7) See more Orthologs mouse all