IGF1, Official Symbol IGF1provided by HGNC Official Full Name insulin like growth factor 1provided by HGNC Primary source HGNC:HGNC:5464 See related Ensembl:ENSG00000017427 MIM:147440; AllianceGenome:HGNC:5464 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IGF; MGF; IGFI; IGF-I Summary The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015] Expression Broad expression in endometrium (RPKM 7.0), fat (RPKM 6.3) and 18 other tissues See more Orthologs mouse all