KLF10, Official Symbol KLF10provided by HGNC Official Full Name KLF transcription factor 10provided by HGNC Primary source HGNC:HGNC:11810 See related Ensembl:ENSG00000155090 MIM:601878; AllianceGenome:HGNC:11810 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EGRA; TIEG; TIEG1; EGR-alpha Summary This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] Expression Ubiquitous expression in bone marrow (RPKM 49.9), gall bladder (RPKM 37.2) and 25 other tissues See more Orthologs mouse all