TBX2, Official Symbol TBX2provided by HGNC Official Full Name T-box transcription factor 2provided by HGNC Primary source HGNC:HGNC:11597 See related Ensembl:ENSG00000121068 MIM:600747; AllianceGenome:HGNC:11597 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VETD Summary This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in lung (RPKM 27.4), placenta (RPKM 24.9) and 18 other tissues See more Orthologs mouse all