AOC3, Official Symbol AOC3provided by HGNC Official Full Name amine oxidase copper containing 3provided by HGNC Primary source HGNC:HGNC:550 See related Ensembl:ENSG00000131471 MIM:603735; AllianceGenome:HGNC:550 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPAO; SSAO; VAP1; VAP-1 Summary This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] Expression Biased expression in fat (RPKM 252.0), lung (RPKM 69.7) and 8 other tissues See more Orthologs mouse all