HRC, Official Symbol HRCprovided by HGNC Official Full Name histidine rich calcium binding proteinprovided by HGNC Primary source HGNC:HGNC:5178 See related Ensembl:ENSG00000130528 MIM:142705; AllianceGenome:HGNC:5178 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcoplasmic reticulum (SR) of skeletal muscle. The protein functions in the regulation of releasable calcium into the SR. [provided by RefSeq, Sep 2008] Expression Restricted expression toward heart (RPKM 206.9) See more Orthologs mouse all