ANKRD17, Official Symbol ANKRD17provided by HGNC Official Full Name ankyrin repeat domain 17provided by HGNC Primary source HGNC:HGNC:23575 See related Ensembl:ENSG00000132466 MIM:615929; AllianceGenome:HGNC:23575 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAGS; GTAR; MASK2; NY-BR-16 Summary The protein encoded by this gene belongs to the family of ankyrin repeat-containing proteins, and contains two distinct arrays of ankyrin repeats in its amino-terminal region, one with 15 ankyrin repeats, and the other with 10 ankyrin repeats. It also contains a nuclear export signal, nuclear localization signal, and a cyclin-binding RXL motif. Localization of this protein to the nucleus has been shown experimentally, and interactions between this protein and cyclin-dependent kinase 2 have been observed. It has been suggested that this protein plays a role in both DNA replication and in both anti-viral and anti-bacterial innate immune pathways. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in brain (RPKM 8.6), thyroid (RPKM 8.6) and 25 other tissues See more Orthologs mouse all