HRH4, Official Symbol HRH4provided by HGNC Official Full Name histamine receptor H4provided by HGNC Primary source HGNC:HGNC:17383 See related Ensembl:ENSG00000134489 MIM:606792; AllianceGenome:HGNC:17383 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H4; H4R; BG26; HH4R; AXOR35; GPRv53; GPCR105 Summary Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Expression Low expression observed in reference dataset See more Orthologs mouse all