PRKX, Official Symbol PRKXprovided by HGNC Official Full Name protein kinase cAMP-dependent X-linked catalytic subunitprovided by HGNC Primary source HGNC:HGNC:9441 See related Ensembl:ENSG00000183943 MIM:300083; AllianceGenome:HGNC:9441 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PKX1 Summary This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y. [provided by RefSeq, Feb 2010] Expression Broad expression in thyroid (RPKM 22.9), kidney (RPKM 7.3) and 20 other tissues See more Orthologs mouse all