KCNJ6, Official Symbol KCNJ6provided by HGNC Official Full Name potassium inwardly rectifying channel subfamily J member 6provided by HGNC Primary source HGNC:HGNC:6267 See related Ensembl:ENSG00000157542 MIM:600877; AllianceGenome:HGNC:6267 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BIR1; GIRK2; KATP2; KCNJ7; KPLBS; GIRK-2; KATP-2; KIR3.2; hiGIRK2 Summary This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015] Expression Biased expression in brain (RPKM 1.1), stomach (RPKM 0.3) and 7 other tissues See more Orthologs mouse all