RB1CC1, Official Symbol RB1CC1provided by HGNC Official Full Name RB1 inducible coiled-coil 1provided by HGNC Primary source HGNC:HGNC:15574 See related Ensembl:ENSG00000023287 MIM:606837; AllianceGenome:HGNC:15574 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CC1; ATG17; FIP200; PPP1R131 Summary The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009] Expression Ubiquitous expression in testis (RPKM 14.7), brain (RPKM 11.4) and 25 other tissues See more Orthologs mouse all