PTP4A3, Official Symbol PTP4A3provided by HGNC Official Full Name protein tyrosine phosphatase 4A3provided by HGNC Primary source HGNC:HGNC:9636 See related Ensembl:ENSG00000184489 MIM:606449; AllianceGenome:HGNC:9636 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRL3; PRL-3; PRL-R Summary This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Broad expression in heart (RPKM 28.7), prostate (RPKM 11.1) and 20 other tissues See more Orthologs mouse all