PPM1K, Official Symbol PPM1Kprovided by HGNC Official Full Name protein phosphatase, Mg2+/Mn2+ dependent 1Kprovided by HGNC Primary source HGNC:HGNC:25415 See related Ensembl:ENSG00000163644 MIM:611065; AllianceGenome:HGNC:25415 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BDP; PTMP; PP2Cm; MSUDMV; PP2Ckappa; UG0882E07 Summary This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012] Expression Broad expression in heart (RPKM 22.0), endometrium (RPKM 10.0) and 22 other tissues See more Orthologs mouse all