MYO1C, Official Symbol MYO1Cprovided by HGNC Official Full Name myosin ICprovided by HGNC Primary source HGNC:HGNC:7597 See related Ensembl:ENSG00000197879 MIM:606538; AllianceGenome:HGNC:7597 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NMI; MMIb; myr2; MyoIC; MMI-beta Summary This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008] Annotation information Note: MYO1C (Gene ID: 4641) and MYO1E (Gene ID: 4643) share the MYO1C symbol/alias in common. MYO1C is a widely used alternative name for myosin IE (MYO1E), which can be confused with the official symbol for myosin IC (MYO1C). [06 Feb 2019] Expression Ubiquitous expression in fat (RPKM 109.9), lung (RPKM 53.1) and 23 other tissues See more Orthologs mouse all