PPP2R1A, Official Symbol PPP2R1Aprovided by HGNC Official Full Name protein phosphatase 2 scaffold subunit Aalphaprovided by HGNC Primary source HGNC:HGNC:9302 See related Ensembl:ENSG00000105568 MIM:605983; AllianceGenome:HGNC:9302 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HJS2; MRD36; PP2AA; PR65A; PP2AAALPHA; PP2A-Aalpha Summary This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010] Expression Ubiquitous expression in heart (RPKM 78.3), adrenal (RPKM 73.7) and 25 other tissues See more Orthologs mouse all