FRS3, Official Symbol FRS3provided by HGNC Official Full Name fibroblast growth factor receptor substrate 3provided by HGNC Primary source HGNC:HGNC:16970 See related Ensembl:ENSG00000137218 MIM:607744; AllianceGenome:HGNC:16970 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SNT2; FRS2B; SNT-2; FRS2beta; FRS2-beta Summary This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013] Expression Broad expression in testis (RPKM 6.0), brain (RPKM 2.3) and 23 other tissues See more Orthologs mouse all