TMBIM1, Official Symbol TMBIM1provided by HGNC Official Full Name transmembrane BAX inhibitor motif containing 1provided by HGNC Primary source HGNC:HGNC:23410 See related Ensembl:ENSG00000135926 MIM:610364; AllianceGenome:HGNC:23410 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LFG3; RECS1; MST100; PP1201; MSTP100 Summary Enables death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Located in Golgi apparatus; endosome membrane; and lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in esophagus (RPKM 69.4), fat (RPKM 68.5) and 25 other tissues See more Orthologs mouse all