CD48, Official Symbol CD48provided by HGNC Official Full Name CD48 moleculeprovided by HGNC Primary source HGNC:HGNC:1683 See related Ensembl:ENSG00000117091 MIM:109530; AllianceGenome:HGNC:1683 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102 Summary This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Biased expression in lymph node (RPKM 70.5), spleen (RPKM 47.2) and 9 other tissues See more Orthologs mouse all