RNF146, Official Symbol RNF146provided by HGNC Official Full Name ring finger protein 146provided by HGNC Primary source HGNC:HGNC:21336 See related Ensembl:ENSG00000118518 MIM:612137; AllianceGenome:HGNC:21336 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Involved in positive regulation of canonical Wnt signaling pathway; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 18.0), lung (RPKM 11.1) and 25 other tissues See more Orthologs mouse all