PIGY, Official Symbol PIGYprovided by HGNC Official Full Name phosphatidylinositol glycan anchor biosynthesis class Yprovided by HGNC Primary source HGNC:HGNC:28213 See related Ensembl:ENSG00000255072 MIM:610662; AllianceGenome:HGNC:28213 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PIG-Y; HPMRS6 Summary The protein encoded by this gene is part of the GPI-N-acetylglucosaminyltransferase (GIP-GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many surface proteins. Proteins containing GPI anchors can have an important role in cell-cell interactions. The transcript for this gene is bicistronic. The downstream open reading frame encodes this GPI-GnT complex protein, while the upstream open reading frame encodes a protein with unknown function, as represented by GeneID:100996939. [provided by RefSeq, Aug 2012] Expression Ubiquitous expression in adrenal (RPKM 45.6), fat (RPKM 42.6) and 25 other tissues See more Orthologs all