FCRL4, Official Symbol FCRL4provided by HGNC Official Full Name Fc receptor like 4provided by HGNC Primary source HGNC:HGNC:18507 See related Ensembl:ENSG00000163518 MIM:605876; AllianceGenome:HGNC:18507 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FCRH4; IGFP2; IRTA1; CD307d Summary This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009] Expression Biased expression in lymph node (RPKM 2.4), appendix (RPKM 2.3) and 5 other tissues See more Orthologs all