PTGES2, Official Symbol PTGES2provided by HGNC Official Full Name prostaglandin E synthase 2provided by HGNC Primary source HGNC:HGNC:17822 See related Ensembl:ENSG00000148334 MIM:608152; AllianceGenome:HGNC:17822 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GBF1; GBF-1; PGES2; C9orf15; mPGES-2 Summary The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009] Expression Ubiquitous expression in heart (RPKM 13.3), kidney (RPKM 10.1) and 25 other tissues See more Orthologs mouse all