MTTP, Official Symbol MTTPprovided by HGNC Official Full Name microsomal triglyceride transfer proteinprovided by HGNC Primary source HGNC:HGNC:7467 See related Ensembl:ENSG00000138823 MIM:157147; AllianceGenome:HGNC:7467 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ABL; MTP Summary MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia. [provided by RefSeq, Jul 2008] Expression Biased expression in small intestine (RPKM 140.0), duodenum (RPKM 122.9) and 1 other tissue See more Orthologs mouse all