PLP2, Official Symbol PLP2provided by HGNC Official Full Name proteolipid protein 2provided by HGNC Primary source HGNC:HGNC:9087 See related Ensembl:ENSG00000102007 MIM:300112; AllianceGenome:HGNC:9087 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A4; A4LSB Summary This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked cognitive disability. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010] Expression Ubiquitous expression in skin (RPKM 154.7), esophagus (RPKM 126.0) and 23 other tissues See more Orthologs mouse all