TLE2, Official Symbol TLE2provided by HGNC Official Full Name TLE family member 2, transcriptional corepressorprovided by HGNC Primary source HGNC:HGNC:11838 See related Ensembl:ENSG00000065717 MIM:601041; AllianceGenome:HGNC:11838 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ESG; ESG2; GRG2 Summary Enables transcription corepressor activity. Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Located in focal adhesion and nuclear body. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in salivary gland (RPKM 17.9), fat (RPKM 13.6) and 24 other tissues See more Orthologs mouse all