PRH2, Official Symbol PRH2provided by HGNC Official Full Name proline rich protein HaeIII subfamily 2provided by HGNC Primary source HGNC:HGNC:9367 See related Ensembl:ENSG00000134551 MIM:168790; AllianceGenome:HGNC:9367 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Pr; pr1/Pr2; PRP-1/PRP-2 Summary This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. In western population this locus is commonly biallelic and encodes proline-rich protein (PRP) isoforms, PRP-1 and PRP-2. The reference genome encodes the PRP-1 allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Oct 2015] Expression Restricted expression toward salivary gland (RPKM 6639.8) See more Orthologs all