TRIM8, Official Symbol TRIM8provided by HGNC Official Full Name tripartite motif containing 8provided by HGNC Primary source HGNC:HGNC:15579 See related Ensembl:ENSG00000171206 MIM:606125; AllianceGenome:HGNC:15579 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GERP; RNF27; FSGSNEDS Summary This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE). [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in kidney (RPKM 42.3), fat (RPKM 41.8) and 25 other tissues See more Orthologs mouse all