UXS1, Official Symbol UXS1provided by HGNC Official Full Name UDP-glucuronate decarboxylase 1provided by HGNC Primary source HGNC:HGNC:17729 See related Ensembl:ENSG00000115652 MIM:609749; AllianceGenome:HGNC:17729 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UGD; hUXS; hUXS1; SDR6E1 Summary This gene encodes an enzyme found in the perinuclear Golgi which catalyzes the synthesis of UDP-xylose used in glycosaminoglycan (GAG) synthesis on proteoglycans. The GAG chains are covalently attached to proteoglycans which participate in signaling pathways during development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in kidney (RPKM 16.4), placenta (RPKM 15.1) and 25 other tissues See more Orthologs mouse all