ARHGAP24, Official Symbol ARHGAP24provided by HGNC Official Full Name Rho GTPase activating protein 24provided by HGNC Primary source HGNC:HGNC:25361 See related Ensembl:ENSG00000138639 MIM:610586; AllianceGenome:HGNC:25361 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p73; FILGAP; RCGAP72; RC-GAP72; p73RhoGAP Summary This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] Expression Broad expression in kidney (RPKM 13.8), thyroid (RPKM 4.3) and 20 other tissues See more Orthologs mouse all