PIP4K2B, Official Symbol PIP4K2Bprovided by HGNC Official Full Name phosphatidylinositol-5-phosphate 4-kinase type 2 betaprovided by HGNC Primary source HGNC:HGNC:8998 See related Ensembl:ENSG00000276293 MIM:603261; AllianceGenome:HGNC:8998 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PI5P4KB; PIP5K2B; PIP5KIIB; PIP5P4KB; PIP5KIIbeta Summary The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 40.4), ovary (RPKM 23.8) and 24 other tissues See more Orthologs mouse all