GTF2F1, Official Symbol GTF2F1provided by HGNC Official Full Name general transcription factor IIF subunit 1provided by HGNC Primary source HGNC:HGNC:4652 See related Ensembl:ENSG00000125651 MIM:189968; AllianceGenome:HGNC:4652 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BTF4; RAP74; TF2F1; TFIIF Summary Enables several functions, including RNA polymerase II general transcription initiation factor activity; phosphatase activator activity; and promoter-specific chromatin binding activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; response to virus; and transcription initiation from RNA polymerase II promoter. Located in cell junction and nucleoplasm. Part of transcription factor TFIID complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 36.8), testis (RPKM 30.9) and 25 other tissues See more Orthologs mouse all