PTN, Official Symbol PTNprovided by HGNC Official Full Name pleiotrophinprovided by HGNC Primary source HGNC:HGNC:9630 See related Ensembl:ENSG00000105894 MIM:162095; AllianceGenome:HGNC:9630 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HARP; HBBM; HBNF; HBGF8; NEGF1; OSF-1; HB-GAM; HBGF-8; HBNF-1 Summary The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016] Expression Broad expression in brain (RPKM 83.5), prostate (RPKM 56.7) and 17 other tissues See more Orthologs mouse all