RHOBTB2, Official Symbol RHOBTB2provided by HGNC Official Full Name Rho related BTB domain containing 2provided by HGNC Primary source HGNC:HGNC:18756 See related Ensembl:ENSG00000008853 MIM:607352; AllianceGenome:HGNC:18756 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p83; DBC2; DEE64; EIEE64 Summary The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Expression Broad expression in lung (RPKM 11.1), brain (RPKM 8.7) and 22 other tissues See more Orthologs mouse all