MCUB, Official Symbol MCUBprovided by HGNC Official Full Name mitochondrial calcium uniporter dominant negative subunit betaprovided by HGNC Primary source HGNC:HGNC:26076 See related Ensembl:ENSG00000005059 AllianceGenome:HGNC:26076 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCDC109B Summary Predicted to enable calcium channel inhibitor activity. Predicted to be involved in calcium import into the mitochondrion and mitochondrial calcium ion homeostasis. Located in mitochondrion and nucleoplasm. Is integral component of mitochondrial inner membrane. Part of uniplex complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lymph node (RPKM 15.3), appendix (RPKM 10.9) and 21 other tissues See more Orthologs mouse all