ACADL, Official Symbol ACADLprovided by HGNC Official Full Name acyl-CoA dehydrogenase long chainprovided by HGNC Primary source HGNC:HGNC:88 See related Ensembl:ENSG00000115361 MIM:609576; AllianceGenome:HGNC:88 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LCAD; ACAD4 Summary The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008] Expression Broad expression in thyroid (RPKM 10.1), fat (RPKM 9.6) and 14 other tissues See more Orthologs mouse all