NUP85, Official Symbol NUP85provided by HGNC Official Full Name nucleoporin 85provided by HGNC Primary source HGNC:HGNC:8734 See related Ensembl:ENSG00000125450 MIM:170285; AllianceGenome:HGNC:8734 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Nup75; FROUNT; NPHS17 Summary This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in lymph node (RPKM 9.1), testis (RPKM 9.0) and 25 other tissues See more Orthologs mouse all