SGSM2, Official Symbol SGSM2provided by HGNC Official Full Name small G protein signaling modulator 2provided by HGNC Primary source HGNC:HGNC:29026 See related Ensembl:ENSG00000141258 MIM:611418; AllianceGenome:HGNC:29026 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RUTBC1 Summary The protein encoded by this gene is a GTPase activator with activity towards RAB32 and RAB33B, which are regulators of membrane trafficking. The encoded protein inactivates RAB32 and can bind RAB9A-GTP, a protein required for RAB32 activation. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in brain (RPKM 17.5), prostate (RPKM 14.3) and 25 other tissues See more Orthologs mouse all