LIMA1, Official Symbol LIMA1provided by HGNC Official Full Name LIM domain and actin binding 1provided by HGNC Primary source HGNC:HGNC:24636 See related Ensembl:ENSG00000050405 MIM:608364; AllianceGenome:HGNC:24636 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPLIN; LDLCQ8; SREBP3 Summary This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in colon (RPKM 57.9), small intestine (RPKM 51.2) and 23 other tissues See more Orthologs mouse all