CARD18, Official Symbol CARD18provided by HGNC Official Full Name caspase recruitment domain family member 18provided by HGNC Primary source HGNC:HGNC:28861 See related Ensembl:ENSG00000255501 MIM:605354; AllianceGenome:HGNC:28861 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ICEBERG; UNQ5804; pseudo-ICE Summary Enables CARD domain binding activity and caspase binding activity. Involved in inhibition of cysteine-type endopeptidase activity; negative regulation of interleukin-1 beta production; and negative regulation of protein binding activity. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in skin (RPKM 6.9) and esophagus (RPKM 0.8) See more Orthologs all