ZNF426, Official Symbol ZNF426provided by HGNC Official Full Name zinc finger protein 426provided by HGNC Primary source HGNC:HGNC:20725 See related Ensembl:ENSG00000130818 AllianceGenome:HGNC:20725 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K-RBP Summary Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in esophagus (RPKM 5.6), ovary (RPKM 2.9) and 25 other tissues See more Orthologs all