TSPAN3, Official Symbol TSPAN3provided by HGNC Official Full Name tetraspanin 3provided by HGNC Primary source HGNC:HGNC:17752 See related Ensembl:ENSG00000140391 MIM:613134; AllianceGenome:HGNC:17752 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TM4-A; TM4SF8; TSPAN-3 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Dec 2009] Expression Ubiquitous expression in fat (RPKM 113.6), colon (RPKM 109.2) and 25 other tissues See more Orthologs mouse all