DEGS2, Official Symbol DEGS2provided by HGNC Official Full Name delta 4-desaturase, sphingolipid 2provided by HGNC Primary source HGNC:HGNC:20113 See related Ensembl:ENSG00000168350 MIM:610862; AllianceGenome:HGNC:20113 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DES2; FADS8; C14orf66 Summary This gene encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. [provided by RefSeq, Oct 2008] Expression Biased expression in small intestine (RPKM 14.4), duodenum (RPKM 11.1) and 13 other tissues See more Orthologs mouse all