TTBK1, Official Symbol TTBK1provided by HGNC Official Full Name tau tubulin kinase 1provided by HGNC Primary source HGNC:HGNC:19140 See related Ensembl:ENSG00000146216 MIM:619415; AllianceGenome:HGNC:19140 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BDTK Summary Summary:This gene belongs to the casein kinase 1 superfamily. The encoded protein is a neuron-specific, serine/threonine and tyrosine kinase, which regulates phosphorylation of tau, a protein that associates with microtubule assemblies and stabilizes them. Genetic variants in this gene are associated with Alzheimer's disease. [provided by RefSeq, Jul 2016] Expression Biased expression in brain (RPKM 4.4), small intestine (RPKM 0.9) and 4 other tissues See more Orthologs mouse all