PLAAT4, Official Symbol PLAAT4provided by HGNC Official Full Name phospholipase A and acyltransferase 4provided by HGNC Primary source HGNC:HGNC:9869 See related Ensembl:ENSG00000133321 MIM:605092; AllianceGenome:HGNC:9869 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIG1; TIG3; HRSL4; HRASLS4; PLAAT-4; RARRES3; PLA1/2-3 Summary Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008] Annotation information Note: RARRES3 (Gene ID: 5920) and DDX58 (Gene ID: 23586) share the RIG1/RIG-1 alias in common. RIG1 is a widely used alternative name for DExD/H-box helicase 58 (DDX58), which can be confused with the retinoic acid receptor responder 3 (RARRES3) gene, since they share the same alias. [22 Jan 2019] Expression Ubiquitous expression in small intestine (RPKM 43.2), duodenum (RPKM 36.6) and 24 other tissues See more Orthologs all