RHOBTB1, Official Symbol RHOBTB1provided by HGNC Official Full Name Rho related BTB domain containing 1provided by HGNC Primary source HGNC:HGNC:18738 See related Ensembl:ENSG00000072422 MIM:607351; AllianceGenome:HGNC:18738 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] Expression Broad expression in placenta (RPKM 10.3), kidney (RPKM 7.3) and 22 other tissues See more Orthologs mouse all