WASF3, Official Symbol WASF3provided by HGNC Official Full Name WASP family member 3provided by HGNC Primary source HGNC:HGNC:12734 See related Ensembl:ENSG00000132970 MIM:605068; AllianceGenome:HGNC:12734 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCAR3; WAVE3; Brush-1 Summary This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014] Expression Broad expression in brain (RPKM 34.0), fat (RPKM 12.7) and 15 other tissues See more Orthologs mouse all