ACSL1, Official Symbol ACSL1provided by HGNC Official Full Name acyl-CoA synthetase long chain family member 1provided by HGNC Primary source HGNC:HGNC:3569 See related Ensembl:ENSG00000151726 MIM:152425; AllianceGenome:HGNC:3569 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACS1; LACS; FACL1; FACL2; LACS1; LACS2 Summary The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] Expression Biased expression in fat (RPKM 357.3), liver (RPKM 217.4) and 10 other tissues See more Orthologs mouse all