DNAJB8, Official Symbol DNAJB8provided by HGNC Official Full Name DnaJ heat shock protein family (Hsp40) member B8provided by HGNC Primary source HGNC:HGNC:23699 See related Ensembl:ENSG00000179407 MIM:611337; AllianceGenome:HGNC:23699 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DJ6; CT156 Summary The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma. [provided by RefSeq, Jun 2012] Expression Restricted expression toward testis (RPKM 16.6) See more Orthologs mouse all