PANK3, Official Symbol PANK3provided by HGNC Official Full Name pantothenate kinase 3provided by HGNC Primary source HGNC:HGNC:19365 See related Ensembl:ENSG00000120137 MIM:606161; AllianceGenome:HGNC:19365 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in duodenum (RPKM 27.0), colon (RPKM 21.4) and 25 other tissues See more Orthologs mouse all