TOX3, Official Symbol TOX3provided by HGNC Official Full Name TOX high mobility group box family member 3provided by HGNC Primary source HGNC:HGNC:11972 See related Ensembl:ENSG00000103460 MIM:611416; AllianceGenome:HGNC:11972 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAGF9; TNRC9 Summary The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009] Expression Biased expression in stomach (RPKM 5.0), colon (RPKM 3.6) and 13 other tissues See more Orthologs mouse all