RAD52, Official Symbol RAD52provided by HGNC Official Full Name RAD52 homolog, DNA repair proteinprovided by HGNC Primary source HGNC:HGNC:9824 See related Ensembl:ENSG00000002016 MIM:600392; AllianceGenome:HGNC:9824 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in fat (RPKM 4.4), skin (RPKM 4.2) and 25 other tissues See more Orthologs mouse all