AOAH, Official Symbol AOAHprovided by HGNC Official Full Name acyloxyacyl hydrolaseprovided by HGNC Primary source HGNC:HGNC:548 See related Ensembl:ENSG00000136250 MIM:102593; AllianceGenome:HGNC:548 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010] Expression Biased expression in spleen (RPKM 9.9), appendix (RPKM 5.8) and 13 other tissues See more Orthologs mouse all