CARMIL2, Official Symbol CARMIL2provided by HGNC Official Full Name capping protein regulator and myosin 1 linker 2provided by HGNC Primary source HGNC:HGNC:27089 See related Ensembl:ENSG00000159753 MIM:610859; AllianceGenome:HGNC:27089 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IMD58; RLTPR; LRRC16C; CARMIL2b Summary This gene encodes a member of the CARMIL (capping protein, Arp2/3, myosin-I linker) family of proteins. The encoded protein interacts with and negatively regulates the heterodimeric capping protein and promotes cell migration. Reduced expression of this gene has been observed in human psoriasis patients. Mutations in this gene cause a human immunodeficiency syndrome characterized by smooth muscle tumors and impaired T-cell function. [provided by RefSeq, May 2017] Expression Biased expression in lymph node (RPKM 12.2), spleen (RPKM 8.2) and 10 other tissues See more Orthologs mouse all