RDH8, Official Symbol RDH8provided by HGNC Official Full Name retinol dehydrogenase 8provided by HGNC Primary source HGNC:HGNC:14423 See related Ensembl:ENSG00000080511 MIM:608575; AllianceGenome:HGNC:14423 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRRDH; SDR28C2 Summary This gene encodes a member of the short-chain dehydrogenase/reductase family. The encoded protein catalyzes the reduction of all-trans-retinal to all-trans-retinol, the first reaction step of the rhodopsin regeneration pathway. This enzymatic reaction is the rate-limiting step in the visual cycle. [provided by RefSeq, Feb 2014] Expression Biased expression in kidney (RPKM 1.0), testis (RPKM 0.7) and 1 other tissue See more Orthologs mouse all