RHBDF1, Official Symbol RHBDF1provided by HGNC Official Full Name rhomboid 5 homolog 1provided by HGNC Primary source HGNC:HGNC:20561 See related Ensembl:ENSG00000007384 MIM:614403; AllianceGenome:HGNC:20561 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Dist1; hDist1; C16orf8; EGFR-RS; gene-89; gene-90 Summary Predicted to enable growth factor binding activity and serine-type endopeptidase activity. Involved in several processes, including negative regulation of protein secretion; regulation of epidermal growth factor receptor signaling pathway; and regulation of proteasomal protein catabolic process. Located in Golgi membrane and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 12.8), prostate (RPKM 9.9) and 24 other tissues See more Orthologs mouse all