RARG, Official Symbol RARGprovided by HGNC Official Full Name retinoic acid receptor gammaprovided by HGNC Primary source HGNC:HGNC:9866 See related Ensembl:ENSG00000172819 MIM:180190; AllianceGenome:HGNC:9866 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RARC; NR1B3; RARgamma Summary This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] Expression Broad expression in skin (RPKM 47.1), esophagus (RPKM 32.0) and 18 other tissues See more Orthologs mouse all