NME8, Official Symbol NME8provided by HGNC Official Full Name NME/NM23 family member 8provided by HGNC Primary source HGNC:HGNC:16473 See related Ensembl:ENSG00000086288 MIM:607421; AllianceGenome:HGNC:16473 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CILD6; DNAI8; SPTRX2; TXNDC3; NM23-H8; sptrx-2; HEL-S-99 Summary This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009] Expression Biased expression in testis (RPKM 4.9), bone marrow (RPKM 3.6) and 3 other tissues See more Orthologs mouse all