NPR3, Official Symbol NPR3provided by HGNC Official Full Name natriuretic peptide receptor 3provided by HGNC Primary source HGNC:HGNC:7945 See related Ensembl:ENSG00000113389 MIM:108962; AllianceGenome:HGNC:7945 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPRC; ANP-C; ANPRC; BOMOS; NPR-C; ANPR-C; GUCY2B; C5orf23 Summary This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] Expression Biased expression in kidney (RPKM 35.4), fat (RPKM 14.2) and 8 other tissues See more Orthologs mouse all