PPP4R4, Official Symbol PPP4R4provided by HGNC Official Full Name protein phosphatase 4 regulatory subunit 4provided by HGNC Primary source HGNC:HGNC:23788 See related Ensembl:ENSG00000119698 MIM:616790; AllianceGenome:HGNC:23788 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP4R4; CFAP14; KIAA1622 Summary The protein encoded by this gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The encoded protein binds protein serine/threonine phosphatase 4c in the cytoplasm. [provided by RefSeq, Jan 2017] Expression Biased expression in brain (RPKM 8.5), testis (RPKM 5.4) and 3 other tissues See more Orthologs mouse all