SCX, Official Symbol SCXprovided by HGNC Official Full Name scleraxis bHLH transcription factorprovided by HGNC Primary source HGNC:HGNC:32322 See related Ensembl:ENSG00000260428 MIM:609067; AllianceGenome:HGNC:32322 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCXA; SCXB; bHLHa48 Summary Enables DNA-binding transcription activator activity, RNA polymerase II-specific and bHLH transcription factor binding activity. Contributes to E-box binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Note: In the NCBI Build GRCh37 reference assembly SCXA and SCXB are duplicate genes in close proximity to each other on chromosome 8. In August, 2010 the Genome Reference Consortium determined that the region contains a duplication error. The clone on which SCXA was based (AC110280.8) was be removed from the GRCh38 reference assembly and SCXB was retained and renamed to SCX. [27 Sep 2015] Expression Ubiquitous expression in appendix (RPKM 1.6), prostate (RPKM 1.6) and 25 other tissues See more Orthologs mouse all