TNFRSF13B, Official Symbol TNFRSF13Bprovided by HGNC Official Full Name TNF receptor superfamily member 13Bprovided by HGNC Primary source HGNC:HGNC:18153 See related Ensembl:ENSG00000240505 MIM:604907; AllianceGenome:HGNC:18153 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B Summary The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] Expression Biased expression in spleen (RPKM 10.1), lymph node (RPKM 5.1) and 6 other tissues See more Orthologs mouse all