PGAM2, Official Symbol PGAM2provided by HGNC Official Full Name phosphoglycerate mutase 2provided by HGNC Primary source HGNC:HGNC:8889 See related Ensembl:ENSG00000164708 MIM:612931; AllianceGenome:HGNC:8889 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GSD10; PGAMM; PGAM-M Summary Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. [provided by RefSeq, Sep 2009] Expression Biased expression in heart (RPKM 250.4), testis (RPKM 58.7) and 2 other tissues See more Orthologs mouse all