SP7, Official Symbol SP7provided by HGNC Official Full Name Sp7 transcription factorprovided by HGNC Primary source HGNC:HGNC:17321 See related Ensembl:ENSG00000170374 MIM:606633; AllianceGenome:HGNC:17321 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OSX; OI11; OI12; osterix Summary This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010] Expression Low expression observed in reference dataset See more Orthologs mouse all