GPR161, Official Symbol GPR161provided by HGNC Official Full Name G protein-coupled receptor 161provided by HGNC Primary source HGNC:HGNC:23694 See related Ensembl:ENSG00000143147 MIM:612250; AllianceGenome:HGNC:23694 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RE2 Summary The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017] Expression Broad expression in endometrium (RPKM 8.0), esophagus (RPKM 3.6) and 20 other tissues See more Orthologs mouse all