HOXD1, Official Symbol HOXD1provided by HGNC Official Full Name homeobox D1provided by HGNC Primary source HGNC:HGNC:5132 See related Ensembl:ENSG00000128645 MIM:142987; AllianceGenome:HGNC:5132 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX4; HOX4G; Hox-4.7 Summary This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 1.7), lung (RPKM 1.6) and 16 other tissues See more Orthologs mouse all