PDE9A, Official Symbol PDE9Aprovided by HGNC Official Full Name phosphodiesterase 9Aprovided by HGNC Primary source HGNC:HGNC:8795 See related Ensembl:ENSG00000160191 MIM:602973; AllianceGenome:HGNC:8795 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSPDE9A2 Summary The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in colon (RPKM 12.5), prostate (RPKM 9.8) and 17 other tissues See more Orthologs mouse all