CCT6B, Official Symbol CCT6Bprovided by HGNC Official Full Name chaperonin containing TCP1 subunit 6Bprovided by HGNC Primary source HGNC:HGNC:1621 See related Ensembl:ENSG00000132141 MIM:610730; AllianceGenome:HGNC:1621 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Cctz2; CCTZ-2; TSA303; CCT-zeta-2; TCP-1-zeta-2 Summary This gene encodes a molecular chaperone that is a member of the chaperonin-containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] Expression Biased expression in testis (RPKM 57.4) and thyroid (RPKM 1.2) See more Orthologs mouse all