PPIB, Official Symbol PPIBprovided by HGNC Official Full Name peptidylprolyl isomerase Bprovided by HGNC Primary source HGNC:HGNC:9255 See related Ensembl:ENSG00000166794 MIM:123841; AllianceGenome:HGNC:9255 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OI9; CYPB; SCYLP; CYP-S1; HEL-S-39 Summary The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in thyroid (RPKM 295.6), placenta (RPKM 241.5) and 25 other tissues See more Orthologs mouse all