FGF23, Official Symbol FGF23provided by HGNC Official Full Name fibroblast growth factor 23provided by HGNC Primary source HGNC:HGNC:3680 See related Ensembl:ENSG00000118972 MIM:605380; AllianceGenome:HGNC:3680 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADHR; FGFN; HYPF; HFTC2; HPDR2; PHPTC Summary This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013] Expression Low expression observed in reference dataset See more Orthologs mouse all