ING1, Official Symbol ING1provided by HGNC Official Full Name inhibitor of growth family member 1provided by HGNC Primary source HGNC:HGNC:6062 See related Ensembl:ENSG00000153487 MIM:601566; AllianceGenome:HGNC:6062 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a Summary This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 5.0), endometrium (RPKM 4.3) and 25 other tissues See more Orthologs mouse all