SARM1, Official Symbol SARM1provided by HGNC Official Full Name sterile alpha and TIR motif containing 1provided by HGNC Primary source HGNC:HGNC:17074 See related Ensembl:ENSG00000004139 MIM:607732; AllianceGenome:HGNC:17074 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SARM; HsTIR; SAMD2; hSARM1; MyD88-5 Summary Enables NAD+ nucleotidase, cyclic ADP-ribose generating and identical protein binding activity. Involved in NAD catabolic process; positive regulation of neuron death; and response to axon injury. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in duodenum (RPKM 30.5), small intestine (RPKM 14.6) and 23 other tissues See more Orthologs mouse all