PAF1, Official Symbol PAF1provided by HGNC Official Full Name PAF1 homolog, Paf1/RNA polymerase II complex componentprovided by HGNC Primary source HGNC:HGNC:25459 See related Ensembl:ENSG00000006712 MIM:610506; AllianceGenome:HGNC:25459 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PD2; F23149_1 Summary This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in testis (RPKM 32.1), ovary (RPKM 17.7) and 25 other tissues See more Orthologs mouse all