ARR3, Official Symbol ARR3provided by HGNC Official Full Name arrestin 3provided by HGNC Primary source HGNC:HGNC:710 See related Ensembl:ENSG00000120500 MIM:301770; AllianceGenome:HGNC:710 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARRX; cArr; MYP26 Summary The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016] Expression Low expression observed in reference dataset See more Orthologs mouse all