SAMHD1, Official Symbol SAMHD1provided by HGNC Official Full Name SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1provided by HGNC Primary source HGNC:HGNC:15925 See related Ensembl:ENSG00000101347 MIM:606754; AllianceGenome:HGNC:15925 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DCIP; CHBL2; HDDC1; MOP-5; SBBI88; hSAMHD1 Summary This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010] Expression Ubiquitous expression in appendix (RPKM 54.7), spleen (RPKM 47.0) and 25 other tissues See more Orthologs mouse all