GUCA1A, Official Symbol GUCA1Aprovided by HGNC Official Full Name guanylate cyclase activator 1Aprovided by HGNC Primary source HGNC:HGNC:4678 See related Ensembl:ENSG00000048545 MIM:600364; AllianceGenome:HGNC:4678 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as COD3; GCAP; GUCA; GCAP1; GUCA1; CORD14; GCAP-1; GCAP-I; C6orf131 Summary This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. provided by RefSeq, Jul 2020] Expression Restricted expression toward testis (RPKM 15.8) See more Orthologs mouse all