FECH, Official Symbol FECHprovided by HGNC Official Full Name ferrochelataseprovided by HGNC Primary source HGNC:HGNC:3647 See related Ensembl:ENSG00000066926 MIM:612386; AllianceGenome:HGNC:3647 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPP; FCE; EPP1 Summary The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010] Expression Broad expression in bone marrow (RPKM 19.5), kidney (RPKM 8.4) and 24 other tissues See more Orthologs mouse all