CDX2, Official Symbol CDX2provided by HGNC Official Full Name caudal type homeobox 2provided by HGNC Primary source HGNC:HGNC:1806 See related Ensembl:ENSG00000165556 MIM:600297; AllianceGenome:HGNC:1806 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDX3; CDX-3; CDX2/AS Summary This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012] Expression Biased expression in colon (RPKM 23.4), small intestine (RPKM 15.9) and 2 other tissues See more Orthologs mouse all