PPP3R1, Official Symbol PPP3R1provided by HGNC Official Full Name protein phosphatase 3 regulatory subunit B, alphaprovided by HGNC Primary source HGNC:HGNC:9317 See related Ensembl:ENSG00000221823 MIM:601302; AllianceGenome:HGNC:9317 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CNB; CNB1; CALNB1 Summary Enables cyclosporin A binding activity; phosphatase binding activity; and protein domain specific binding activity. Involved in calcineurin-NFAT signaling cascade and positive regulation of transcription by RNA polymerase II. Part of calcineurin complex. Implicated in Alzheimer's disease and dilated cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 81.4), fat (RPKM 34.1) and 24 other tissues See more Orthologs mouse all