DGAT2, Official Symbol DGAT2provided by HGNC Official Full Name diacylglycerol O-acyltransferase 2provided by HGNC Primary source HGNC:HGNC:16940 See related Ensembl:ENSG00000062282 MIM:606983; AllianceGenome:HGNC:16940 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARAT; HMFN1045; GS1999FULL Summary This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Biased expression in fat (RPKM 381.0), liver (RPKM 87.8) and 1 other tissue See more Orthologs mouse all