ALDOC, Official Symbol ALDOCprovided by HGNC Official Full Name aldolase, fructose-bisphosphate Cprovided by HGNC Primary source HGNC:HGNC:418 See related Ensembl:ENSG00000109107 MIM:103870; AllianceGenome:HGNC:418 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALDC Summary This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 270.0), fat (RPKM 67.7) and 5 other tissues See more Orthologs mouse all