CCKBR, Official Symbol CCKBRprovided by HGNC Official Full Name cholecystokinin B receptorprovided by HGNC Primary source HGNC:HGNC:1571 See related Ensembl:ENSG00000110148 MIM:118445; AllianceGenome:HGNC:1571 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GASR; CCK-B; CCK2R; CCK-2R Summary This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Dec 2015] Expression Biased expression in stomach (RPKM 4.6), brain (RPKM 2.9) and 2 other tissues See more Orthologs mouse all