NAPSA, Official Symbol NAPSAprovided by HGNC Official Full Name napsin A aspartic peptidaseprovided by HGNC Primary source HGNC:HGNC:13395 See related Ensembl:ENSG00000131400 MIM:605631; AllianceGenome:HGNC:13395 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KAP; Kdap; NAP1; NAPA; SNAPA Summary This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016] Expression Restricted expression toward lung (RPKM 393.9) See more Orthologs mouse all