OXTR, Official Symbol OXTRprovided by HGNC Official Full Name oxytocin receptorprovided by HGNC Primary source HGNC:HGNC:8529 See related Ensembl:ENSG00000180914 MIM:167055; AllianceGenome:HGNC:8529 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OTR; OT-R Summary The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008] Expression Broad expression in ovary (RPKM 1.0), endometrium (RPKM 1.0) and 16 other tissues See more Orthologs mouse all