KLHL17, Official Symbol KLHL17provided by HGNC Official Full Name kelch like family member 17provided by HGNC Primary source HGNC:HGNC:24023 See related Ensembl:ENSG00000187961 MIM:619262; AllianceGenome:HGNC:24023 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AF Summary The protein encoded by this gene is expressed in neurons of most regions of the brain. It contains an N-terminal BTB domain, which mediates dimerization of the protein, and a C-terminal Kelch domain, which mediates binding to F-actin. This protein may play a key role in the regulation of actin-based neuronal function. [provided by RefSeq, Aug 2010] Expression Ubiquitous expression in testis (RPKM 3.5), skin (RPKM 2.8) and 24 other tissues See more Orthologs mouse all