PIGX, Official Symbol PIGXprovided by HGNC Official Full Name phosphatidylinositol glycan anchor biosynthesis class Xprovided by HGNC Primary source HGNC:HGNC:26046 See related Ensembl:ENSG00000163964 MIM:610276; AllianceGenome:HGNC:26046 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PIG-X Summary This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in brain (RPKM 7.7), prostate (RPKM 7.3) and 25 other tissues See more Orthologs mouse all