PTENP1, Official Symbol PTENP1provided by HGNC Official Full Name phosphatase and tensin homolog pseudogene 1provided by HGNC Primary source HGNC:HGNC:9589 See related Ensembl:ENSG00000237984 MIM:613531; AllianceGenome:HGNC:9589 Gene type pseudo RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PTH2; PTEN2; PTEN-rs; PTENpg1; psiPTEN Summary PTENP1 represents a highly homologous processed pseudogene of PTEN (phosphatase and tensin homolog), a protein that encodes a tumor suppressor that functions by negatively regulating the AKT/PKB signaling pathway. PTENP1 is found on chromosome 9 and regulates PTEN by both sense and antisense RNAs (Gene ID: 101243555). This long-noncoding RNA (lncRNA) acts as a decoy for PTEN targeting microRNAs and also exerts a tumor suppressive activity. [provided by RefSeq, Jun 2020]