LSAMP, Official Symbol LSAMPprovided by HGNC Official Full Name limbic system associated membrane proteinprovided by HGNC Primary source HGNC:HGNC:6705 See related Ensembl:ENSG00000185565 MIM:603241; AllianceGenome:HGNC:6705 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LAMP; IGLON3 Summary This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] Expression Biased expression in brain (RPKM 19.9), prostate (RPKM 5.4) and 9 other tissues See more Orthologs mouse all