L3HYPDH, Official Symbol L3HYPDHprovided by HGNC Official Full Name trans-L-3-hydroxyproline dehydrataseprovided by HGNC Primary source HGNC:HGNC:20488 See related Ensembl:ENSG00000126790 MIM:614811; AllianceGenome:HGNC:20488 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C14orf149 Summary The protein encoded by this gene is a dehydratase that converts trans-3-hydroxy-L-proline to delta(1)-pyrroline-2-carboxylate. This enzyme may function to degrade dietary proteins that contain trans-3-hydroxy-L-proline as well as other proteins such as collagen IV. The encoded protein can be converted to an epimerase by changing a threonine to a cysteine at a catalytic site. [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in testis (RPKM 6.0), prostate (RPKM 5.0) and 25 other tissues See more Orthologs mouse all