CERK, Official Symbol CERKprovided by HGNC Official Full Name ceramide kinaseprovided by HGNC Primary source HGNC:HGNC:19256 See related Ensembl:ENSG00000100422 MIM:610307; AllianceGenome:HGNC:19256 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LK4; hCERK; dA59H18.2; dA59H18.3 Summary CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in small intestine (RPKM 16.4), duodenum (RPKM 15.6) and 25 other tissues See more Orthologs mouse all