FERMT2, Official Symbol FERMT2provided by HGNC Official Full Name FERM domain containing kindlin 2provided by HGNC Primary source HGNC:HGNC:15767 See related Ensembl:ENSG00000073712 MIM:607746; AllianceGenome:HGNC:15767 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B Summary Enables several functions, including actin binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell differentiation; and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol; focal adhesion; and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 84.8), endometrium (RPKM 56.1) and 22 other tissues See more Orthologs mouse all