PTPN9, Official Symbol PTPN9provided by HGNC Official Full Name protein tyrosine phosphatase non-receptor type 9provided by HGNC Primary source HGNC:HGNC:9661 See related Ensembl:ENSG00000169410 MIM:600768; AllianceGenome:HGNC:9661 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MEG2; PTPMEG2 Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 22.0), small intestine (RPKM 10.6) and 25 other tissues See more Orthologs mouse all