QTRT1, Official Symbol QTRT1provided by HGNC Official Full Name queuine tRNA-ribosyltransferase catalytic subunit 1provided by HGNC Primary source HGNC:HGNC:23797 See related Ensembl:ENSG00000213339 MIM:609615; AllianceGenome:HGNC:23797 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TGT; TGUT; FP3235 Summary This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in ovary (RPKM 18.9), thyroid (RPKM 17.4) and 25 other tissues See more Orthologs mouse all