CERNA2, Official Symbol CERNA2provided by HGNC Official Full Name competing endogenous lncRNA 2 for microRNA let-7bprovided by HGNC Primary source HGNC:HGNC:51354 See related Ensembl:ENSG00000285972 MIM:617434; AllianceGenome:HGNC:51354 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOST2; lncRNA-HOST2 Summary This gene produces a long non-coding transcript that functions in ovarian carcinogenesis by promoting tumor cell migration, invasion and proliferation. It binds to the microRNA let-7b (MIRLET7B), which is a potent tumor suppressor, thereby inhibiting the functions of that microRNA by modulating its availability to its targets. [provided by RefSeq, Dec 2015] Expression Biased expression in esophagus (RPKM 3.5), endometrium (RPKM 2.9) and 6 other tissues See more