RTCB, Official Symbol RTCBprovided by HGNC Official Full Name RNA 2',3'-cyclic phosphate and 5'-OH ligaseprovided by HGNC Primary source HGNC:HGNC:26935 See related Ensembl:ENSG00000100220 MIM:613901; AllianceGenome:HGNC:26935 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAAP; HSPC117; C22orf28; DJ149A16.6 Summary Enables RNA ligase (ATP) activity and vinculin binding activity. Involved in tRNA splicing, via endonucleolytic cleavage and ligation. Located in cytosol and nucleoplasm. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in duodenum (RPKM 45.6), small intestine (RPKM 40.2) and 25 other tissues See more Orthologs mouse all