GAN, Official Symbol GANprovided by HGNC Official Full Name gigaxoninprovided by HGNC Primary source HGNC:HGNC:4137 See related Ensembl:ENSG00000261609 MIM:605379; AllianceGenome:HGNC:4137 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GIG; GAN1; KLHL16 Summary This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq, Oct 2008] Expression Broad expression in skin (RPKM 5.8), esophagus (RPKM 2.0) and 23 other tissues See more Orthologs mouse all