NLRP9, Official Symbol NLRP9provided by HGNC Official Full Name NLR family pyrin domain containing 9provided by HGNC Primary source HGNC:HGNC:22941 See related Ensembl:ENSG00000185792 MIM:609663; AllianceGenome:HGNC:22941 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOD6; NALP9; PAN12; CLR19.1 Summary The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008] Expression Biased expression in prostate (RPKM 1.0), testis (RPKM 0.4) and 9 other tissues See more Orthologs all