MGST3, Official Symbol MGST3provided by HGNC Official Full Name microsomal glutathione S-transferase 3provided by HGNC Primary source HGNC:HGNC:7064 See related Ensembl:ENSG00000143198 MIM:604564; AllianceGenome:HGNC:7064 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GST-3; GST-III Summary This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011] Expression Ubiquitous expression in heart (RPKM 114.7), fat (RPKM 75.6) and 24 other tissues See more Orthologs mouse all