INSL3, Official Symbol INSL3provided by HGNC Official Full Name insulin like 3provided by HGNC Primary source HGNC:HGNC:6086 See related Ensembl:ENSG00000248099 MIM:146738; AllianceGenome:HGNC:6086 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RLF; RLNL; ley-I-L Summary This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012] Expression Restricted expression toward testis (RPKM 240.7) See more Orthologs mouse all