THBS1, Official Symbol THBS1provided by HGNC Official Full Name thrombospondin 1provided by HGNC Primary source HGNC:HGNC:11785 See related Ensembl:ENSG00000137801 MIM:188060; AllianceGenome:HGNC:11785 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSP; THBS; TSP1; TSP-1; THBS-1 Summary The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008] Expression Broad expression in appendix (RPKM 304.9), gall bladder (RPKM 219.5) and 16 other tissues See more Orthologs mouse all