CSPP1, Official Symbol CSPP1provided by HGNC Official Full Name centrosome and spindle pole associated protein 1provided by HGNC Primary source HGNC:HGNC:26193 See related Ensembl:ENSG00000104218 MIM:611654; AllianceGenome:HGNC:26193 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CSPP; CSPP-L; JBTS21 Summary This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014] Expression Broad expression in testis (RPKM 7.4), kidney (RPKM 3.8) and 25 other tissues See more Orthologs mouse all