PRDX6, Official Symbol PRDX6provided by HGNC Official Full Name peroxiredoxin 6provided by HGNC Primary source HGNC:HGNC:16753 See related Ensembl:ENSG00000117592 MIM:602316; AllianceGenome:HGNC:16753 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; LPCAT-5; HEL-S-128m Summary The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 236.1), liver (RPKM 127.7) and 25 other tissues See more Orthologs mouse all