BGN, Official Symbol BGNprovided by HGNC Official Full Name biglycanprovided by HGNC Primary source HGNC:HGNC:1044 See related Ensembl:ENSG00000182492 MIM:301870; AllianceGenome:HGNC:1044 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGI; MRLS; DSPG1; PG-S1; SEMDX; SLRR1A Summary This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015] Expression Broad expression in gall bladder (RPKM 206.5), spleen (RPKM 159.3) and 20 other tissues See more Orthologs mouse all