NAPRT, Official Symbol NAPRTprovided by HGNC Official Full Name nicotinate phosphoribosyltransferaseprovided by HGNC Primary source HGNC:HGNC:30450 See related Ensembl:ENSG00000147813 MIM:611552; AllianceGenome:HGNC:30450 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAPRT1; PP3856 Summary Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in duodenum (RPKM 19.1), small intestine (RPKM 16.7) and 25 other tissues See more Orthologs mouse all