KCNQ5, Official Symbol KCNQ5provided by HGNC Official Full Name potassium voltage-gated channel subfamily Q member 5provided by HGNC Primary source HGNC:HGNC:6299 See related Ensembl:ENSG00000185760 MIM:607357; AllianceGenome:HGNC:6299 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Kv7.5; MRD46 Summary This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Expression Biased expression in brain (RPKM 8.7), thyroid (RPKM 2.7) and 6 other tissues See more Orthologs mouse all