KRT19, Official Symbol KRT19provided by HGNC Official Full Name keratin 19provided by HGNC Primary source HGNC:HGNC:6436 See related Ensembl:ENSG00000171345 MIM:148020; AllianceGenome:HGNC:6436 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K19; CK19; K1CS Summary The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 351.9), stomach (RPKM 332.4) and 13 other tissues See more Orthologs mouse all