FCER1A, Official Symbol FCER1Aprovided by HGNC Official Full Name Fc epsilon receptor Iaprovided by HGNC Primary source HGNC:HGNC:3609 See related Ensembl:ENSG00000179639 MIM:147140; AllianceGenome:HGNC:3609 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FCE1A; FcERI; FCERIA Summary The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011] Expression Broad expression in skin (RPKM 12.7), esophagus (RPKM 10.4) and 20 other tissues See more Orthologs mouse all