PCGF6, Official Symbol PCGF6provided by HGNC Official Full Name polycomb group ring finger 6provided by HGNC Primary source HGNC:HGNC:21156 See related Ensembl:ENSG00000156374 MIM:607816; AllianceGenome:HGNC:21156 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MBLR; RNF134 Summary The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 6.3), fat (RPKM 4.5) and 25 other tissues See more Orthologs mouse all