MEST, Official Symbol MESTprovided by HGNC Official Full Name mesoderm specific transcriptprovided by HGNC Primary source HGNC:HGNC:7028 See related Ensembl:ENSG00000106484 MIM:601029; AllianceGenome:HGNC:7028 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PEG1 Summary This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011] Expression Biased expression in placenta (RPKM 292.2), fat (RPKM 48.4) and 6 other tissues See more Orthologs mouse all