COL4A2, Official Symbol COL4A2provided by HGNC Official Full Name collagen type IV alpha 2 chainprovided by HGNC Primary source HGNC:HGNC:2203 See related Ensembl:ENSG00000134871 MIM:120090; AllianceGenome:HGNC:2203 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ICH; BSVD2; POREN2 Summary This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008] Expression Biased expression in placenta (RPKM 373.6), fat (RPKM 158.9) and 13 other tissues See more Orthologs mouse all