TAL1, Official Symbol TAL1provided by HGNC Official Full Name TAL bHLH transcription factor 1, erythroid differentiation factorprovided by HGNC Primary source HGNC:HGNC:11556 See related Ensembl:ENSG00000162367 MIM:187040; AllianceGenome:HGNC:11556 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCL; TCL5; tal-1; bHLHa17 Summary Enables several functions, including DNA-binding transcription factor activity; E-box binding activity; and histone deacetylase binding activity. Involved in several processes, including myeloid cell differentiation; positive regulation of cellular component organization; and positive regulation of erythrocyte differentiation. Located in chromatin and nucleoplasm. Part of transcription regulator complex. Implicated in acute lymphoblastic leukemia. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 7.9), fat (RPKM 4.0) and 18 other tissues See more Orthologs mouse all