BHLHE41, Official Symbol BHLHE41provided by HGNC Official Full Name basic helix-loop-helix family member e41provided by HGNC Primary source HGNC:HGNC:16617 See related Ensembl:ENSG00000123095 MIM:606200; AllianceGenome:HGNC:16617 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEC2; FNSS1; hDEC2; BHLHB3; SHARP1 Summary This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, Feb 2014] Expression Broad expression in thyroid (RPKM 31.2), brain (RPKM 21.3) and 19 other tissues See more Orthologs mouse all