KDM4D, Official Symbol KDM4Dprovided by HGNC Official Full Name lysine demethylase 4Dprovided by HGNC Primary source HGNC:HGNC:25498 See related Ensembl:ENSG00000186280 MIM:609766; AllianceGenome:HGNC:25498 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JMJD2D Summary Enables histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K9 demethylation. Acts upstream of or within several processes, including cellular response to ionizing radiation; positive regulation of chromatin binding activity; and positive regulation of double-strand break repair via nonhomologous end joining. Located in site of double-strand break. Biomarker of nephroblastoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 26.3) and brain (RPKM 0.6) See more Orthologs mouse all