IFT140, Official Symbol IFT140provided by HGNC Official Full Name intraflagellar transport 140provided by HGNC Primary source HGNC:HGNC:29077 See related Ensembl:ENSG00000187535 MIM:614620; AllianceGenome:HGNC:29077 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP80; MZSDS; SRTD9; WDTC2; gs114; c305C8.4; c380F5.1 Summary This gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the flow of fluid, light or odors, and transduces those signals to the nucleus. Loss of the corresponding protein in mouse results in renal cystic disease. [provided by RefSeq, Jun 2012] Expression Broad expression in testis (RPKM 6.4), thyroid (RPKM 4.0) and 24 other tissues See more Orthologs mouse all