NDC80, Official Symbol NDC80provided by HGNC Official Full Name NDC80 kinetochore complex componentprovided by HGNC Primary source HGNC:HGNC:16909 See related Ensembl:ENSG00000080986 MIM:607272; AllianceGenome:HGNC:16909 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80 Summary This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011] Expression Broad expression in testis (RPKM 8.6), lymph node (RPKM 8.5) and 16 other tissues See more Orthologs mouse all