SLC2A4, Official Symbol SLC2A4provided by HGNC Official Full Name solute carrier family 2 member 4provided by HGNC Primary source HGNC:HGNC:11009 See related Ensembl:ENSG00000181856 MIM:138190; AllianceGenome:HGNC:11009 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUT4 Summary This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008] Expression Biased expression in heart (RPKM 32.2), fat (RPKM 24.5) and 6 other tissues See more Orthologs mouse all