PYCR3, Official Symbol PYCR3provided by HGNC Official Full Name pyrroline-5-carboxylate reductase 3provided by HGNC Primary source HGNC:HGNC:25846 See related Ensembl:ENSG00000104524 MIM:616408; AllianceGenome:HGNC:25846 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PYCRL Summary This gene encodes a protein that belongs to the pyrroline-5-carboxylate reductase family of enzymes. Members of this family catalyze the final step in proline biosynthesis, converting pyrroline-5-carboxylate to proline. Glutamate and ornithine are precursors in the synthesis of proline. The protein encoded by this gene is a cytoplasmic enzyme involved in the biosynthesis of proline from ornithine. [provided by RefSeq, Aug 2016] Expression Ubiquitous expression in kidney (RPKM 2.8), thyroid (RPKM 2.6) and 25 other tissues See more Orthologs mouse all