SPSB2, Official Symbol SPSB2provided by HGNC Official Full Name splA/ryanodine receptor domain and SOCS box containing 2provided by HGNC Primary source HGNC:HGNC:29522 See related Ensembl:ENSG00000111671 MIM:611658; AllianceGenome:HGNC:29522 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SSB2; GRCC9 Summary This gene encodes a member of a subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal suppressor of cytokine signaling (SOCS) box. This protein plays a role in cell signaling. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Expression Broad expression in brain (RPKM 50.3), appendix (RPKM 44.2) and 19 other tissues See more Orthologs mouse all