PMPCA, Official Symbol PMPCAprovided by HGNC Official Full Name peptidase, mitochondrial processing subunit alphaprovided by HGNC Primary source HGNC:HGNC:18667 See related Ensembl:ENSG00000165688 MIM:613036; AllianceGenome:HGNC:18667 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLA1; CPD3; MAS2; P-55; SCAR2; INPP5E; Alpha-MPP Summary The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in heart (RPKM 12.6), testis (RPKM 12.5) and 25 other tissues See more Orthologs mouse all