TRIM26, Official Symbol TRIM26provided by HGNC Official Full Name tripartite motif containing 26provided by HGNC Primary source HGNC:HGNC:12962 See related Ensembl:ENSG00000234127 MIM:600830; AllianceGenome:HGNC:12962 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AFP; RNF95; ZNF173 Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011] Expression Ubiquitous expression in kidney (RPKM 14.9), spleen (RPKM 12.6) and 25 other tissues See more Orthologs mouse all