TUBB3, Official Symbol TUBB3provided by HGNC Official Full Name tubulin beta 3 class IIIprovided by HGNC Primary source HGNC:HGNC:20772 See related Ensembl:ENSG00000258947 MIM:602661; AllianceGenome:HGNC:20772 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A Summary This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010] Expression Broad expression in brain (RPKM 82.3), testis (RPKM 29.3) and 18 other tissues See more Orthologs mouse all