TBC1D8B, Official Symbol TBC1D8Bprovided by HGNC Official Full Name TBC1 domain family member 8Bprovided by HGNC Primary source HGNC:HGNC:24715 See related Ensembl:ENSG00000133138 MIM:301027; AllianceGenome:HGNC:24715 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPHS20; GRAMD8B Summary This gene encodes a protein with a TBC (Tre-2/Bub2/CDC16) domain. Some mammalian proteins with this domain have been shown to function as Rab-GAPs by binding to specific Rab proteins and affecting their GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] Expression Broad expression in adrenal (RPKM 10.0), thyroid (RPKM 3.7) and 23 other tissues See more Orthologs mouse all