SH2D3C, Official Symbol SH2D3Cprovided by HGNC Official Full Name SH2 domain containing 3Cprovided by HGNC Primary source HGNC:HGNC:16884 See related Ensembl:ENSG00000095370 MIM:604722; AllianceGenome:HGNC:16884 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHAT; NSP3; SHEP1; PRO34088 Summary This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Expression Broad expression in spleen (RPKM 12.4), lung (RPKM 10.5) and 22 other tissues See more Orthologs mouse all