IRX6, Official Symbol IRX6provided by HGNC Official Full Name iroquois homeobox 6provided by HGNC Primary source HGNC:HGNC:14675 See related Ensembl:ENSG00000159387 MIM:606196; AllianceGenome:HGNC:14675 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IRX7; IRX-3; IRXB3 Summary Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell development; neuron differentiation; and regulation of transcription, DNA-templated. Predicted to act upstream of or within detection of visible light; negative regulation of transcription, DNA-templated; and retina morphogenesis in camera-type eye. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in fat (RPKM 7.9), heart (RPKM 3.1) and 5 other tissues See more Orthologs mouse all