FBXO46, Official Symbol FBXO46provided by HGNC Official Full Name F-box protein 46provided by HGNC Primary source HGNC:HGNC:25069 See related Ensembl:ENSG00000177051 MIM:609117; AllianceGenome:HGNC:25069 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx46; FBXO34L; 20D7-FC4 Summary Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in spleen (RPKM 4.8), testis (RPKM 4.4) and 25 other tissues See more Orthologs mouse all