TBR1, Official Symbol TBR1provided by HGNC Official Full Name T-box brain transcription factor 1provided by HGNC Primary source HGNC:HGNC:11590 See related Ensembl:ENSG00000136535 MIM:604616; AllianceGenome:HGNC:11590 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AUTS5; IDDAS; TBR-1; TES-56 Summary This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015] Expression Restricted expression toward brain (RPKM 13.1) See more Orthologs mouse all