SYDE1, Official Symbol SYDE1provided by HGNC Official Full Name synapse defective Rho GTPase homolog 1provided by HGNC Primary source HGNC:HGNC:25824 See related Ensembl:ENSG00000105137 MIM:617377; AllianceGenome:HGNC:25824 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 7h3; SYD1 Summary The protein encoded by this gene is a Rho GTPase-activating protein highly expressed in placenta. The encoded protein is involved in cytoskeletal remodeling and trophoblast cell migration. Decreased expression of this gene has been associated with intrauterine growth restriction (IUGR). [provided by RefSeq, Feb 2017] Expression Ubiquitous expression in fat (RPKM 9.3), placenta (RPKM 9.2) and 23 other tissues See more Orthologs mouse all