CYP4B1, Official Symbol CYP4B1provided by HGNC Official Full Name cytochrome P450 family 4 subfamily B member 1provided by HGNC Primary source HGNC:HGNC:2644 See related Ensembl:ENSG00000142973 MIM:124075; AllianceGenome:HGNC:2644 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CYPIVB1; P-450HP Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016] Annotation information Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene. Expression Biased expression in lung (RPKM 169.4), fat (RPKM 49.5) and 3 other tissues See more Orthologs mouse all