MAST1, Official Symbol MAST1provided by HGNC Official Full Name microtubule associated serine/threonine kinase 1provided by HGNC Primary source HGNC:HGNC:19034 See related Ensembl:ENSG00000105613 MIM:612256; AllianceGenome:HGNC:19034 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAST; MCCCHCM Summary This gene is a member of the microtubule-associated serine/threonine kinase (MAST) family. The protein encoded by this gene has an N-terminal serine/threonine kinase domain followed by a postsynaptic density protein-95/discs large/zona occludens-1 (PDZ) domain. In mouse and rat, the orthologous protein associates with the cytoskeleton and can bind both beta-2-syntrophin and neuronal nitric oxide synthase (nNOS) through its PDZ domain. In mouse and rat, this protein also co-localizes with dystrophin- and utrophin-associated protein complexes (DAPC/UAPC) in the vascular endothelium of the central nervous system. [provided by RefSeq, May 2017] Expression Biased expression in brain (RPKM 10.3), testis (RPKM 1.3) and 1 other tissue See more Orthologs mouse all