SLC25A20, Official Symbol SLC25A20provided by HGNC Official Full Name solute carrier family 25 member 20provided by HGNC Primary source HGNC:HGNC:1421 See related Ensembl:ENSG00000178537 MIM:613698; AllianceGenome:HGNC:1421 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAC; CACT Summary This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in liver (RPKM 37.3), duodenum (RPKM 32.0) and 25 other tissues See more Orthologs mouse all