LAMA1, Official Symbol LAMA1provided by HGNC Official Full Name laminin subunit alpha 1provided by HGNC Primary source HGNC:HGNC:6481 See related Ensembl:ENSG00000101680 MIM:150320; AllianceGenome:HGNC:6481 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LAMA; PTBHS; S-LAM-alpha Summary This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014] Expression Biased expression in testis (RPKM 6.1), thyroid (RPKM 2.2) and 8 other tissues See more Orthologs mouse all