GRHPR, Official Symbol GRHPRprovided by HGNC Official Full Name glyoxylate and hydroxypyruvate reductaseprovided by HGNC Primary source HGNC:HGNC:4570 See related Ensembl:ENSG00000137106 MIM:604296; AllianceGenome:HGNC:4570 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PH2; GLXR; GLYD Summary This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in liver (RPKM 132.9), kidney (RPKM 67.4) and 24 other tissues See more Orthologs mouse all