PCDH11Y, Official Symbol PCDH11Yprovided by HGNC Official Full Name protocadherin 11 Y-linkedprovided by HGNC Primary source HGNC:HGNC:15813 See related Ensembl:ENSG00000099715 MIM:400022; AllianceGenome:HGNC:15813 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCDHX; PCDHY; PCDH22; PCDH-PC Summary This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] Expression Biased expression in brain (RPKM 1.4), ovary (RPKM 0.6) and 5 other tissues See more