NUDT10, Official Symbol NUDT10provided by HGNC Official Full Name nudix hydrolase 10provided by HGNC Primary source HGNC:HGNC:17621 See related Ensembl:ENSG00000122824 MIM:300527; AllianceGenome:HGNC:17621 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APS2; DIPP3a; DIPP3-alpha Summary This gene is a member of the nudix (nucleoside diphosphate linked moiety X)-type motif containing family. The encoded protein is a phosphohydrolase and may regulate the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to the regulation of intracellular trafficking. In some populations putative prostate cancer susceptibility alleles have been identified for this gene. Alternatively spliced transcript variants, which differ only in the 5' UTR, have been found for this gene. [provided by RefSeq, Feb 2015] Expression Biased expression in testis (RPKM 20.6), brain (RPKM 8.6) and 6 other tissues See more Orthologs all