EXOC1, Official Symbol EXOC1provided by HGNC Official Full Name exocyst complex component 1provided by HGNC Primary source HGNC:HGNC:30380 See related Ensembl:ENSG00000090989 MIM:607879; AllianceGenome:HGNC:30380 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SEC3; SEC3P; BM-102; SEC3L1 Summary The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 10.9), skin (RPKM 9.9) and 25 other tissues See more Orthologs mouse all