SCO1, Official Symbol SCO1provided by HGNC Official Full Name synthesis of cytochrome C oxidase 1provided by HGNC Primary source HGNC:HGNC:10603 See related Ensembl:ENSG00000133028 MIM:603644; AllianceGenome:HGNC:10603 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCOD1; MC4DN4 Summary Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in colon (RPKM 11.6), kidney (RPKM 11.1) and 25 other tissues See more Orthologs mouse all