SASS6, Official Symbol SASS6provided by HGNC Official Full Name SAS-6 centriolar assembly proteinprovided by HGNC Primary source HGNC:HGNC:25403 See related Ensembl:ENSG00000156876 MIM:609321; AllianceGenome:HGNC:25403 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAS6; SAS-6; MCPH14 Summary The protein encoded by this gene is a central component of centrioles and is necessary for their duplication and function. Centrioles adopt a cartwheel-shaped structure, with the encoded protein forming the hub and spokes inside a microtubule cylinder. Defects in this gene are a cause of autosomal recessive primary microcephaly. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in bone marrow (RPKM 6.8), testis (RPKM 6.7) and 25 other tissues See more Orthologs mouse all