LIPC, Official Symbol LIPCprovided by HGNC Official Full Name lipase C, hepatic typeprovided by HGNC Primary source HGNC:HGNC:6619 See related Ensembl:ENSG00000166035 MIM:151670; AllianceGenome:HGNC:6619 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HL; HTGL; LIPH; HDLCQ12 Summary Enables phospholipase A1 activity and triglyceride lipase activity. Involved in several processes, including lipid homeostasis; plasma lipoprotein particle remodeling; and triglyceride catabolic process. Located in extracellular space. Implicated in several diseases, including Alzheimer's disease; coronary artery disease; familial combined hyperlipidemia; peripheral vascular disease; and type 2 diabetes mellitus. Biomarker of hyperinsulinism; obesity; and type 1 diabetes mellitus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in liver (RPKM 24.9) and kidney (RPKM 1.5) See more Orthologs mouse all