CC2D1A, Official Symbol CC2D1Aprovided by HGNC Official Full Name coiled-coil and C2 domain containing 1Aprovided by HGNC Primary source HGNC:HGNC:30237 See related Ensembl:ENSG00000132024 MIM:610055; AllianceGenome:HGNC:30237 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Lgd2; MRT3; TAPE; Aki-1; FREUD-1; Freud-1/Aki1 Summary This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in a nonsyndromic form of cognitive disability (MRT3). [provided by RefSeq, Jul 2017] Expression Ubiquitous expression in duodenum (RPKM 16.8), small intestine (RPKM 12.5) and 25 other tissues See more Orthologs mouse all