CPA6, Official Symbol CPA6provided by HGNC Official Full Name carboxypeptidase A6provided by HGNC Primary source HGNC:HGNC:17245 See related Ensembl:ENSG00000165078 MIM:609562; AllianceGenome:HGNC:17245 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPAH; ETL5; FEB11 Summary The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome. [provided by RefSeq, May 2016] Expression Biased expression in prostate (RPKM 1.2), colon (RPKM 0.8) and 7 other tissues See more Orthologs mouse all