PPM1E, Official Symbol PPM1Eprovided by HGNC Official Full Name protein phosphatase, Mg2+/Mn2+ dependent 1Eprovided by HGNC Primary source HGNC:HGNC:19322 See related Ensembl:ENSG00000175175 MIM:619308; AllianceGenome:HGNC:19322 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as POPX1; PP2CH; caMKN; CAMKPN; CaMKP-N Summary This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] Expression Biased expression in brain (RPKM 6.5), testis (RPKM 3.8) and 3 other tissues See more Orthologs mouse all