CCT2, Official Symbol CCT2provided by HGNC Official Full Name chaperonin containing TCP1 subunit 2provided by HGNC Primary source HGNC:HGNC:1615 See related Ensembl:ENSG00000166226 MIM:605139; AllianceGenome:HGNC:1615 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCTB; 99D8.1; PRO1633; CCT-beta; HEL-S-100n; TCP-1-beta Summary The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] Expression Broad expression in testis (RPKM 107.5), bone marrow (RPKM 41.1) and 24 other tissues See more Orthologs mouse all