IARS2, Official Symbol IARS2provided by HGNC Official Full Name isoleucyl-tRNA synthetase 2, mitochondrialprovided by HGNC Primary source HGNC:HGNC:29685 See related Ensembl:ENSG00000067704 MIM:612801; AllianceGenome:HGNC:29685 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ILERS; CAGSSS Summary Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in fat (RPKM 38.4), kidney (RPKM 32.0) and 25 other tissues See more Orthologs mouse all