NFYC, Official Symbol NFYCprovided by HGNC Official Full Name nuclear transcription factor Y subunit gammaprovided by HGNC Primary source HGNC:HGNC:7806 See related Ensembl:ENSG00000066136 MIM:605344; AllianceGenome:HGNC:7806 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSM; CBFC; HAP5; CBF-C; NF-YC; H1TF2A Summary This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] Expression Ubiquitous expression in thyroid (RPKM 9.6), heart (RPKM 9.5) and 25 other tissues See more Orthologs mouse all