FLT3LG, Official Symbol FLT3LGprovided by HGNC Official Full Name fms related receptor tyrosine kinase 3 ligandprovided by HGNC Primary source HGNC:HGNC:3766 See related Ensembl:ENSG00000090554 MIM:600007; AllianceGenome:HGNC:3766 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FL; FLG3L; FLT3L Summary Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011] Expression Ubiquitous expression in spleen (RPKM 4.5), lymph node (RPKM 4.2) and 24 other tissues See more Orthologs mouse all