PRRC2A, Official Symbol PRRC2Aprovided by HGNC Official Full Name proline rich coiled-coil 2Aprovided by HGNC Primary source HGNC:HGNC:13918 See related Ensembl:ENSG00000204469 MIM:142580; AllianceGenome:HGNC:13918 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G2; BAT2; D6S51; D6S51E Summary A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010] Expression Broad expression in testis (RPKM 81.0), ovary (RPKM 32.9) and 25 other tissues See more Orthologs mouse all