ECI1, Official Symbol ECI1provided by HGNC Official Full Name enoyl-CoA delta isomerase 1provided by HGNC Primary source HGNC:HGNC:2703 See related Ensembl:ENSG00000167969 MIM:600305; AllianceGenome:HGNC:2703 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DCI Summary This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010] Expression Ubiquitous expression in kidney (RPKM 39.8), colon (RPKM 22.9) and 25 other tissues See more Orthologs mouse all