CREB1, Official Symbol CREB1provided by HGNC Official Full Name cAMP responsive element binding protein 1provided by HGNC Primary source HGNC:HGNC:2345 See related Ensembl:ENSG00000118260 MIM:123810; AllianceGenome:HGNC:2345 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CREB; CREB-1 Summary This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in lymph node (RPKM 5.0), thyroid (RPKM 4.7) and 25 other tissues See more Orthologs mouse all