GMIP, Official Symbol GMIPprovided by HGNC Official Full Name GEM interacting proteinprovided by HGNC Primary source HGNC:HGNC:24852 See related Ensembl:ENSG00000089639 MIM:609694; AllianceGenome:HGNC:24852 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHGAP46 Summary This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Expression Broad expression in spleen (RPKM 20.3), bone marrow (RPKM 16.1) and 21 other tissues See more Orthologs mouse all