VSIR, Official Symbol VSIRprovided by HGNC Official Full Name V-set immunoregulatory receptorprovided by HGNC Primary source HGNC:HGNC:30085 See related Ensembl:ENSG00000107738 MIM:615608; AllianceGenome:HGNC:30085 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B7H5; GI24; B7-H5; Dies1; PD-1H; SISP1; VISTA; PP2135; C10orf54; DD1alpha Summary Enables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of macromolecule metabolic process; and regulation of T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 39.2), bone marrow (RPKM 38.8) and 23 other tissues See more Orthologs mouse all