ITSN1, Official Symbol ITSN1provided by HGNC Official Full Name intersectin 1provided by HGNC Primary source HGNC:HGNC:6183 See related Ensembl:ENSG00000205726 MIM:602442; AllianceGenome:HGNC:6183 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ITSN; SH3D1A; SH3P17 Summary The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 8.8), brain (RPKM 4.1) and 24 other tissues See more Orthologs mouse all