SELENBP1, Official Symbol SELENBP1provided by HGNC Official Full Name selenium binding protein 1provided by HGNC Primary source HGNC:HGNC:10719 See related Ensembl:ENSG00000143416 MIM:604188; AllianceGenome:HGNC:10719 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MTO; LPSB; SP56; hSBP; EHMTO; SBP56; HEL-S-134P Summary This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012] Expression Broad expression in colon (RPKM 232.0), lung (RPKM 124.7) and 17 other tissues See more Orthologs all