AKR1D1, Official Symbol AKR1D1provided by HGNC Official Full Name aldo-keto reductase family 1 member D1provided by HGNC Primary source HGNC:HGNC:388 See related Ensembl:ENSG00000122787 MIM:604741; AllianceGenome:HGNC:388 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CBAS2; SRD5B1; 3o5bred Summary The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010] Expression Restricted expression toward liver (RPKM 96.8) See more Orthologs mouse all