PDS5B, Official Symbol PDS5Bprovided by HGNC Official Full Name PDS5 cohesin associated factor Bprovided by HGNC Primary source HGNC:HGNC:20418 See related Ensembl:ENSG00000083642 MIM:605333; AllianceGenome:HGNC:20418 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AS3; APRIN; CG008 Summary This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, Jul 2015] Expression Ubiquitous expression in brain (RPKM 8.3), endometrium (RPKM 8.1) and 25 other tissues See more Orthologs mouse all