CACNB1, Official Symbol CACNB1provided by HGNC Official Full Name calcium voltage-gated channel auxiliary subunit beta 1provided by HGNC Primary source HGNC:HGNC:1401 See related Ensembl:ENSG00000067191 MIM:114207; AllianceGenome:HGNC:1401 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAB1; CCHLB1; CACNLB1 Summary The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 12.9), skin (RPKM 4.4) and 17 other tissues See more Orthologs mouse all