HOXA10, Official Symbol HOXA10provided by HGNC Official Full Name homeobox A10provided by HGNC Primary source HGNC:HGNC:5100 See related Ensembl:ENSG00000253293 MIM:142957; AllianceGenome:HGNC:5100 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PL; HOX1; HOX1H; HOX1.8 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene. [provided by RefSeq, Mar 2011] Expression Biased expression in endometrium (RPKM 36.7), prostate (RPKM 13.4) and 7 other tissues See more Orthologs mouse all