ADAR, Official Symbol ADARprovided by HGNC Official Full Name adenosine deaminase RNA specificprovided by HGNC Primary source HGNC:HGNC:225 See related Ensembl:ENSG00000160710 MIM:146920; AllianceGenome:HGNC:225 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP Summary This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010] Expression Ubiquitous expression in spleen (RPKM 49.6), appendix (RPKM 40.8) and 25 other tissues See more Orthologs mouse all