CACYBP, Official Symbol CACYBPprovided by HGNC Official Full Name calcyclin binding proteinprovided by HGNC Primary source HGNC:HGNC:30423 See related Ensembl:ENSG00000116161 MIM:606186; AllianceGenome:HGNC:30423 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIP; GIG5; PNAS-107; S100A6BP Summary The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 20.4), ovary (RPKM 13.4) and 25 other tissues See more Orthologs mouse all