CDKL5, Official Symbol CDKL5provided by HGNC Official Full Name cyclin dependent kinase like 5provided by HGNC Primary source HGNC:HGNC:11411 See related Ensembl:ENSG00000008086 MIM:300203; AllianceGenome:HGNC:11411 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEE2; ISSX; STK9; EIEE2; CFAP247 Summary This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 11.1), lung (RPKM 3.0) and 18 other tissues See more Orthologs mouse all