PDGFD, Official Symbol PDGFDprovided by HGNC Official Full Name platelet derived growth factor Dprovided by HGNC Primary source HGNC:HGNC:30620 See related Ensembl:ENSG00000170962 MIM:609673; AllianceGenome:HGNC:30620 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IEGF; SCDGFB; MSTP036; SCDGF-B Summary The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in adrenal (RPKM 66.8), ovary (RPKM 41.5) and 13 other tissues See more Orthologs mouse all