CCR4, Official Symbol CCR4provided by HGNC Official Full Name C-C motif chemokine receptor 4provided by HGNC Primary source HGNC:HGNC:1605 See related Ensembl:ENSG00000183813 MIM:604836; AllianceGenome:HGNC:1605 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CKR4; K5-5; CD194; CMKBR4; ChemR13; CC-CKR-4; HGCN:14099 Summary The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008] Expression Biased expression in appendix (RPKM 6.5), urinary bladder (RPKM 6.3) and 12 other tissues See more Orthologs mouse all