SRGAP2C, Official Symbol SRGAP2Cprovided by HGNC Official Full Name SLIT-ROBO Rho GTPase activating protein 2Cprovided by HGNC Primary source HGNC:HGNC:30584 See related Ensembl:ENSG00000171943 MIM:614704; AllianceGenome:HGNC:30584 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SRGAP2P1 Summary This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. This human-specific locus resulted from segmental duplication of the SLIT-ROBO Rho GTPase activating protein 2B locus. The encoded protein lacks the GTPase activating protein domain compared to proteins encoded by SLIT-ROBO Rho GTPase activating protein 2, and acts antagonistically to these proteins in cortical neuron development. [provided by RefSeq, Dec 2012] Expression Ubiquitous expression in skin (RPKM 12.8), spleen (RPKM 10.6) and 23 other tissues See more