DGKA, Official Symbol DGKAprovided by HGNC Official Full Name diacylglycerol kinase alphaprovided by HGNC Primary source HGNC:HGNC:2849 See related Ensembl:ENSG00000065357 MIM:125855; AllianceGenome:HGNC:2849 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DAGK; DAGK1; DGK-alpha Summary The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Several transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2017] Expression Broad expression in lymph node (RPKM 36.2), skin (RPKM 31.7) and 19 other tissues See more Orthologs mouse all