RNF130, Official Symbol RNF130provided by HGNC Official Full Name ring finger protein 130provided by HGNC Primary source HGNC:HGNC:18280 See related Ensembl:ENSG00000113269 MIM:619163; AllianceGenome:HGNC:18280 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GP; G1RP; G1RZFP; GOLIATH Summary The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Ubiquitous expression in fat (RPKM 11.3), brain (RPKM 9.7) and 25 other tissues See more Orthologs mouse all