TRIB1, Official Symbol TRIB1provided by HGNC Official Full Name tribbles pseudokinase 1provided by HGNC Primary source HGNC:HGNC:16891 See related Ensembl:ENSG00000173334 MIM:609461; AllianceGenome:HGNC:16891 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C8FW; GIG2; TRB1; GIG-2; SKIP1; TRB-1 Summary Enables mitogen-activated protein kinase kinase binding activity and protein kinase inhibitor activity. Involved in several processes, including JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; and regulation of protein kinase activity. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 87.7), liver (RPKM 53.0) and 20 other tissues See more Orthologs mouse all