RPS6KA3, Official Symbol RPS6KA3provided by HGNC Official Full Name ribosomal protein S6 kinase A3provided by HGNC Primary source HGNC:HGNC:10432 See related Ensembl:ENSG00000177189 MIM:300075; AllianceGenome:HGNC:10432 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLS; RSK; HU-3; RSK2; MRX19; ISPK-1; XLID19; p90-RSK2; pp90RSK2; MAPKAPK1B; S6K-alpha3 Summary This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in appendix (RPKM 16.2), colon (RPKM 16.0) and 25 other tissues See more Orthologs mouse all