CD33, Official Symbol CD33provided by HGNC Official Full Name CD33 moleculeprovided by HGNC Primary source HGNC:HGNC:1659 See related Ensembl:ENSG00000105383 MIM:159590; AllianceGenome:HGNC:1659 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p67; SIGLEC3; SIGLEC-3 Summary Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 7.5), bone marrow (RPKM 6.6) and 19 other tissues See more Orthologs mouse all