TNFRSF6B, Official Symbol TNFRSF6Bprovided by HGNC Official Full Name TNF receptor superfamily member 6bprovided by HGNC Primary source HGNC:HGNC:11921 See related Ensembl:ENSG00000243509 MIM:603361; AllianceGenome:HGNC:11921 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as M68; TR6; DCR3; M68E; DJ583P15.1.1 Summary This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011] Expression Broad expression in appendix (RPKM 7.2), spleen (RPKM 3.2) and 20 other tissues See more Orthologs all