NDUFB9, Official Symbol NDUFB9provided by HGNC Official Full Name NADH:ubiquinone oxidoreductase subunit B9provided by HGNC Primary source HGNC:HGNC:7704 See related Ensembl:ENSG00000147684 MIM:601445; AllianceGenome:HGNC:7704 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B22; LYRM3; CI-B22; UQOR22; MC1DN24 Summary The protein encoded by this gene is a subunit of the mitochondrial oxidative phosphorylation complex I (nicotinamide adenine dinucleotide: ubiquinone oxidoreductase). Complex I is localized to the inner mitochondrial membrane and functions to dehydrogenate nicotinamide adenine dinucleotide and to shuttle electrons to coenzyme Q. Complex I deficiency is the most common defect found in oxidative phosphorylation disorders and results in a range of conditions, including lethal neonatal disease, hypertrophic cardiomyopathy, liver disease, and adult-onset neurodegenerative disorders. Pseudogenes of this gene are found on chromosomes five, seven and eight. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] Expression Ubiquitous expression in heart (RPKM 119.4), kidney (RPKM 111.6) and 25 other tissues See more Orthologs mouse all