ASAP3, Official Symbol ASAP3provided by HGNC Official Full Name ArfGAP with SH3 domain, ankyrin repeat and PH domain 3provided by HGNC Primary source HGNC:HGNC:14987 See related Ensembl:ENSG00000088280 MIM:616594; AllianceGenome:HGNC:14987 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACAP4; UPLC1; CENTB6; DDEFL1 Summary This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] Expression Ubiquitous expression in ovary (RPKM 21.1), skin (RPKM 19.0) and 23 other tissues See more Orthologs mouse all