MUC4, Official Symbol MUC4provided by HGNC Official Full Name mucin 4, cell surface associatedprovided by HGNC Primary source HGNC:HGNC:7514 See related Ensembl:ENSG00000145113 MIM:158372; AllianceGenome:HGNC:7514 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ASGP; MUC-4; HSA276359 Summary The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008] Annotation information Annotation category: suggests misassembly Expression Biased expression in colon (RPKM 10.3), esophagus (RPKM 2.1) and 4 other tissues See more Orthologs mouse all