NUPR1, Official Symbol NUPR1provided by HGNC Official Full Name nuclear protein 1, transcriptional regulatorprovided by HGNC Primary source HGNC:HGNC:29990 See related Ensembl:ENSG00000176046 MIM:614812; AllianceGenome:HGNC:29990 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P8; COM1 Summary Enables DNA binding activity and transcription coactivator activity. Involved in several processes, including regulation of cellular catabolic process; regulation of generation of precursor metabolites and energy; and regulation of programmed cell death. Acts upstream of or within negative regulation of cell cycle. Located in intercellular bridge; nucleoplasm; and perinuclear region of cytoplasm. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 197.1), pancreas (RPKM 192.3) and 21 other tissues See more Orthologs mouse all