FCGR2B, Official Symbol FCGR2Bprovided by HGNC Official Full Name Fc gamma receptor IIbprovided by HGNC Primary source HGNC:HGNC:3618 See related Ensembl:ENSG00000072694 MIM:604590; AllianceGenome:HGNC:3618 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD32; FCG2; CD32B; FCGR2; IGFR2; FCGR2C; FcGRIIB; FcRII-c; FcgammaRIIb Summary The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Expression Biased expression in placenta (RPKM 92.9), appendix (RPKM 9.6) and 6 other tissues See more Orthologs all