IQSEC3, Official Symbol IQSEC3provided by HGNC Official Full Name IQ motif and Sec7 domain ArfGEF 3provided by HGNC Primary source HGNC:HGNC:29193 See related Ensembl:ENSG00000120645 MIM:612118; AllianceGenome:HGNC:29193 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including actin cytoskeleton organization; activation of GTPase activity; and regulation of small GTPase mediated signal transduction. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 5.8), fat (RPKM 2.6) and 12 other tissues See more Orthologs mouse all