DGKB, Official Symbol DGKBprovided by HGNC Official Full Name diacylglycerol kinase betaprovided by HGNC Primary source HGNC:HGNC:2850 See related Ensembl:ENSG00000136267 MIM:604070; AllianceGenome:HGNC:2850 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DGK; DAGK2; DGK-BETA Summary Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017] Expression Biased expression in brain (RPKM 7.2), adrenal (RPKM 0.9) and 2 other tissues See more Orthologs mouse all