STX1B, Official Symbol STX1Bprovided by HGNC Official Full Name syntaxin 1Bprovided by HGNC Primary source HGNC:HGNC:18539 See related Ensembl:ENSG00000099365 MIM:601485; AllianceGenome:HGNC:18539 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GEFSP9; STX1B1; STX1B2 Summary The protein encoded by this gene belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested. [provided by RefSeq, Jan 2015] Expression Biased expression in brain (RPKM 32.7) and testis (RPKM 1.4) See more Orthologs mouse all