MAPRE2, Official Symbol MAPRE2provided by HGNC Official Full Name microtubule associated protein RP/EB family member 2provided by HGNC Primary source HGNC:HGNC:6891 See related Ensembl:ENSG00000166974 MIM:605789; AllianceGenome:HGNC:6891 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EB1; EB2; RP1; CSCSC2 Summary The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] Expression Ubiquitous expression in brain (RPKM 59.8), heart (RPKM 31.4) and 24 other tissues See more Orthologs mouse all