PPM1G, Official Symbol PPM1Gprovided by HGNC Official Full Name protein phosphatase, Mg2+/Mn2+ dependent 1Gprovided by HGNC Primary source HGNC:HGNC:9278 See related Ensembl:ENSG00000115241 MIM:605119; AllianceGenome:HGNC:9278 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP2CG; PPP2CG; PP2CGAMMA Summary The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010] Expression Broad expression in testis (RPKM 133.0), lymph node (RPKM 28.8) and 24 other tissues See more Orthologs mouse all