TNIP1, Official Symbol TNIP1provided by HGNC Official Full Name TNFAIP3 interacting protein 1provided by HGNC Primary source HGNC:HGNC:16903 See related Ensembl:ENSG00000145901 MIM:607714; AllianceGenome:HGNC:16903 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VAN; NAF1; ABIN-1; nip40-1 Summary This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Expression Ubiquitous expression in fat (RPKM 55.9), spleen (RPKM 36.4) and 25 other tissues See more Orthologs mouse all