RORB, Official Symbol RORBprovided by HGNC Official Full Name RAR related orphan receptor Bprovided by HGNC Primary source HGNC:HGNC:10259 See related Ensembl:ENSG00000198963 MIM:601972; AllianceGenome:HGNC:10259 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RZRB; EIG15; NR1F2; ROR-BETA; RZR-BETA; bA133M9.1 Summary The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014] Expression Biased expression in brain (RPKM 5.4), endometrium (RPKM 3.4) and 9 other tissues See more Orthologs mouse all