BTN2A3P, Official Symbol BTN2A3Pprovided by HGNC Official Full Name butyrophilin subfamily 2 member A3, pseudogeneprovided by HGNC Primary source HGNC:HGNC:13229 See related Ensembl:ENSG00000291104 MIM:613592; AllianceGenome:HGNC:13229 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BTN2.3; BTN2A3 Summary The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A3) and BTN3 (e.g., BNT3A1; MIM 613593) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010] Expression Ubiquitous expression in endometrium (RPKM 1.5), spleen (RPKM 1.4) and 24 other tissues See more