NSD3, Official Symbol NSD3provided by HGNC Official Full Name nuclear receptor binding SET domain protein 3provided by HGNC Primary source HGNC:HGNC:12767 See related Ensembl:ENSG00000147548 MIM:607083; AllianceGenome:HGNC:12767 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KMT3F; KMT3G; WHISTLE; WHSC1L1; pp14328 Summary This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015] Expression Ubiquitous expression in ovary (RPKM 10.0), brain (RPKM 9.8) and 25 other tissues See more Orthologs mouse all