TNRC6A, Official Symbol TNRC6Aprovided by HGNC Official Full Name trinucleotide repeat containing adaptor 6Aprovided by HGNC Primary source HGNC:HGNC:11969 See related Ensembl:ENSG00000090905 MIM:610739; AllianceGenome:HGNC:11969 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GW1; FAME6; GW182; TNRC6; CAGH26 Summary This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 11.5), endometrium (RPKM 10.0) and 25 other tissues See more Orthologs mouse all