RAD54L, Official Symbol RAD54Lprovided by HGNC Official Full Name RAD54 likeprovided by HGNC Primary source HGNC:HGNC:9826 See related Ensembl:ENSG00000085999 MIM:603615; AllianceGenome:HGNC:9826 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HR54; hHR54; RAD54A; hRAD54 Summary The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008] Expression Broad expression in testis (RPKM 5.9), lymph node (RPKM 2.7) and 15 other tissues See more Orthologs mouse all