SNRPA1, Official Symbol SNRPA1provided by HGNC Official Full Name small nuclear ribonucleoprotein polypeptide A'provided by HGNC Primary source HGNC:HGNC:11152 See related Ensembl:ENSG00000131876 MIM:603521; AllianceGenome:HGNC:11152 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Lea1; U2A' Summary Enables RNA binding activity. Involved in mRNA splicing, via spliceosome and spermatogenesis. Located in nuclear speck. Part of U2-type catalytic step 2 spliceosome and U2-type precatalytic spliceosome. Implicated in connective tissue disease. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 26.0), testis (RPKM 22.8) and 25 other tissues See more Orthologs mouse all