TGM5, Official Symbol TGM5provided by HGNC Official Full Name transglutaminase 5provided by HGNC Primary source HGNC:HGNC:11781 See related Ensembl:ENSG00000104055 MIM:603805; AllianceGenome:HGNC:11781 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TGX; PSS2; TGM6; TGMX; TG(X); TGASE5; TGASEX Summary This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009] Expression Biased expression in skin (RPKM 7.6), esophagus (RPKM 3.4) and 1 other tissue See more Orthologs mouse all