LTBR, Official Symbol LTBRprovided by HGNC Official Full Name lymphotoxin beta receptorprovided by HGNC Primary source HGNC:HGNC:6718 See related Ensembl:ENSG00000111321 MIM:600979; AllianceGenome:HGNC:6718 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TNFCR; TNFR3; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III Summary This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] Expression Ubiquitous expression in prostate (RPKM 23.4), placenta (RPKM 23.0) and 25 other tissues See more Orthologs mouse all