KLK15, Official Symbol KLK15provided by HGNC Official Full Name kallikrein related peptidase 15provided by HGNC Primary source HGNC:HGNC:20453 See related Ensembl:ENSG00000174562 MIM:610601; AllianceGenome:HGNC:20453 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACO; HSRNASPH Summary Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] Expression Biased expression in colon (RPKM 1.2), testis (RPKM 1.0) and 5 other tissues See more Orthologs mouse all