CACNA1E, Official Symbol CACNA1Eprovided by HGNC Official Full Name calcium voltage-gated channel subunit alpha1 Eprovided by HGNC Primary source HGNC:HGNC:1392 See related Ensembl:ENSG00000198216 MIM:601013; AllianceGenome:HGNC:1392 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BII; CACH6; DEE69; gm139; Cav2.3; EIEE69; CACNL1A6 Summary Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011] Expression Biased expression in brain (RPKM 3.3), adrenal (RPKM 0.4) and 2 other tissues See more Orthologs mouse all