SYT1, Official Symbol SYT1provided by HGNC Official Full Name synaptotagmin 1provided by HGNC Primary source HGNC:HGNC:11509 See related Ensembl:ENSG00000067715 MIM:185605; AllianceGenome:HGNC:11509 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P65; SYT; BAGOS; SVP65 Summary This gene encodes a member of the synaptotagmin protein family. The synaptotagmins are integral membrane proteins of synaptic vesicles that serve as calcium sensors in the process of vesicular trafficking and exocytosis. The encoded protein participates in triggering neurotransmitter release at the synapse in response to calcium binding. Mutations in this gene are associated with Baker-Gordon syndrome. [provided by RefSeq, Jan 2023] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is locus in the vicinity of disease-associated variant(s). Expression Biased expression in brain (RPKM 173.4) and adrenal (RPKM 11.7) See more Orthologs mouse all