TPH2, Official Symbol TPH2provided by HGNC Official Full Name tryptophan hydroxylase 2provided by HGNC Primary source HGNC:HGNC:20692 See related Ensembl:ENSG00000139287 MIM:607478; AllianceGenome:HGNC:20692 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NTPH; ADHD7 Summary This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016] Expression Low expression observed in reference dataset See more Orthologs mouse all