CYP4F12, Official Symbol CYP4F12provided by HGNC Official Full Name cytochrome P450 family 4 subfamily F member 12provided by HGNC Primary source HGNC:HGNC:18857 See related Ensembl:ENSG00000186204 MIM:611485; AllianceGenome:HGNC:18857 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CYPIVF12; F22329_1 Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] Expression Biased expression in small intestine (RPKM 23.2), duodenum (RPKM 22.3) and 10 other tissues See more Orthologs all