OTUD7A, Official Symbol OTUD7Aprovided by HGNC Official Full Name OTU deubiquitinase 7Aprovided by HGNC Primary source HGNC:HGNC:20718 See related Ensembl:ENSG00000169918 MIM:612024; AllianceGenome:HGNC:20718 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OTUD7; C15orf16; C16ORF15; CEZANNE2 Summary The protein encoded by this gene is a deubiquitinizing enzyme and possible tumor suppressor. The encoded protein acts on TNF receptor associated factor 6 (TRAF6) to control nuclear factor kappa B expression. However, this gene is downregulated by SNAIL1 in hepatocellular carcinoma cells, contributing to their progression and malignancy. [provided by RefSeq, Aug 2016] Expression Broad expression in brain (RPKM 2.7), testis (RPKM 2.0) and 18 other tissues See more Orthologs mouse all