PSMD10, Official Symbol PSMD10provided by HGNC Official Full Name proteasome 26S subunit, non-ATPase 10provided by HGNC Primary source HGNC:HGNC:9555 See related Ensembl:ENSG00000101843 MIM:300880; AllianceGenome:HGNC:9555 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p28; p28(GANK); dJ889N15.2 Summary This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.[provided by RefSeq, Mar 2011] Expression Ubiquitous expression in brain (RPKM 23.6), thyroid (RPKM 20.0) and 25 other tissues See more Orthologs mouse all