PLXNA3, Official Symbol PLXNA3provided by HGNC Official Full Name plexin A3provided by HGNC Primary source HGNC:HGNC:9101 See related Ensembl:ENSG00000130827 MIM:300022; AllianceGenome:HGNC:9101 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 6.3; PLXN3; PLXN4; XAP-6; HSSEXGENE Summary This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in skin (RPKM 7.2), ovary (RPKM 7.2) and 25 other tissues See more Orthologs mouse all