DARS2, Official Symbol DARS2provided by HGNC Official Full Name aspartyl-tRNA synthetase 2, mitochondrialprovided by HGNC Primary source HGNC:HGNC:25538 See related Ensembl:ENSG00000117593 MIM:610956; AllianceGenome:HGNC:25538 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LBSL; ASPRS; mtAspRS; MT-ASPRS Summary The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). [provided by RefSeq, Nov 2009] Expression Ubiquitous expression in kidney (RPKM 7.7), colon (RPKM 6.8) and 25 other tissues See more Orthologs mouse all