MAPK13, Official Symbol MAPK13provided by HGNC Official Full Name mitogen-activated protein kinase 13provided by HGNC Primary source HGNC:HGNC:6875 See related Ensembl:ENSG00000156711 MIM:602899; AllianceGenome:HGNC:6875 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAPK4; PRKM13; MAPK 13; MAPK-13; p38delta Summary This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012] Expression Broad expression in skin (RPKM 21.7), small intestine (RPKM 17.1) and 22 other tissues See more Orthologs mouse all