KMT5C, Official Symbol KMT5Cprovided by HGNC Official Full Name lysine methyltransferase 5Cprovided by HGNC Primary source HGNC:HGNC:28405 See related Ensembl:ENSG00000133247 MIM:613198; AllianceGenome:HGNC:28405 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SUV420H2; Suv4-20h2 Summary SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009] Expression Ubiquitous expression in bone marrow (RPKM 1.9), placenta (RPKM 1.5) and 25 other tissues See more Orthologs mouse all