INPP5A, Official Symbol INPP5Aprovided by HGNC Official Full Name inositol polyphosphate-5-phosphatase Aprovided by HGNC Primary source HGNC:HGNC:6076 See related Ensembl:ENSG00000068383 MIM:600106; AllianceGenome:HGNC:6076 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 5PTASE Summary The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 7.6), testis (RPKM 4.7) and 25 other tissues See more Orthologs mouse all