MICAL1, Official Symbol MICAL1provided by HGNC Official Full Name microtubule associated monooxygenase, calponin and LIM domain containing 1provided by HGNC Primary source HGNC:HGNC:20619 See related Ensembl:ENSG00000135596 MIM:607129; AllianceGenome:HGNC:20619 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MICAL; NICAL; MICAL-1 Summary This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] Expression Ubiquitous expression in bone marrow (RPKM 31.4), lymph node (RPKM 25.8) and 23 other tissues See more Orthologs mouse all