RAET1G, Official Symbol RAET1Gprovided by HGNC Official Full Name retinoic acid early transcript 1Gprovided by HGNC Primary source HGNC:HGNC:16795 See related Ensembl:ENSG00000203722 MIM:609244; AllianceGenome:HGNC:16795 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ULBP5 Summary This gene encodes a member of the major histocompatibility complex (MHC) class I family of proteins. Although the encoded protein includes C-terminal transmembrane and cytoplasmic domains, proteolytic processing results in the removal of these domains and subsequent tethering to the plasma membrane by a glycosylphosphatidylinositol (GPI)-anchor. The encoded protein is one of several related ligands of the natural killer group 2, member D (NKG2D) receptor, which functions as an activating receptor in innate and adaptive immunity. This gene is present in a gene cluster on chromosome 6. [provided by RefSeq, Jul 2015] Expression Biased expression in esophagus (RPKM 1.3), adrenal (RPKM 0.9) and 11 other tissues See more Orthologs all