NANOG, Official Symbol NANOGprovided by HGNC Official Full Name Nanog homeoboxprovided by HGNC Primary source HGNC:HGNC:20857 See related Ensembl:ENSG00000111704 MIM:607937; AllianceGenome:HGNC:20857 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] Expression Low expression observed in reference dataset See more Orthologs mouse all