KCNMB2, Official Symbol KCNMB2provided by HGNC Official Full Name potassium calcium-activated channel subfamily M regulatory beta subunit 2provided by HGNC Primary source HGNC:HGNC:6286 See related Ensembl:ENSG00000197584 MIM:605214; AllianceGenome:HGNC:6286 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described. [provided by RefSeq, Jul 2013] Expression Biased expression in ovary (RPKM 5.5), adrenal (RPKM 2.4) and 8 other tissues See more Orthologs mouse all