CEACAM5, Official Symbol CEACAM5provided by HGNC Official Full Name CEA cell adhesion molecule 5provided by HGNC Primary source HGNC:HGNC:1817 See related Ensembl:ENSG00000105388 MIM:114890; AllianceGenome:HGNC:1817 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CEA; CD66e Summary This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] Expression Biased expression in colon (RPKM 540.8), appendix (RPKM 102.3) and 2 other tissues See more Orthologs all