SNTG1, Official Symbol SNTG1provided by HGNC Official Full Name syntrophin gamma 1provided by HGNC Primary source HGNC:HGNC:13740 See related Ensembl:ENSG00000147481 MIM:608714; AllianceGenome:HGNC:13740 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SYN4; G1SYN Summary The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This family member plays a role in mediating gamma-enolase trafficking to the plasma membrane and in enhancing its neurotrophic activity. Mutations in this gene are associated with idiopathic scoliosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] Expression Biased expression in brain (RPKM 1.6), spleen (RPKM 0.7) and 2 other tissues See more Orthologs mouse all