SPINK1, Official Symbol SPINK1provided by HGNC Official Full Name serine peptidase inhibitor Kazal type 1provided by HGNC Primary source HGNC:HGNC:11244 See related Ensembl:ENSG00000164266 MIM:167790; AllianceGenome:HGNC:11244 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TCP; PCTT; PSTI; TATI; Spink3 Summary The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008] Expression Biased expression in pancreas (RPKM 2401.2), stomach (RPKM 337.4) and 2 other tissues See more Orthologs mouse all