ASF1B, Official Symbol ASF1Bprovided by HGNC Official Full Name anti-silencing function 1B histone chaperoneprovided by HGNC Primary source HGNC:HGNC:20996 See related Ensembl:ENSG00000105011 MIM:609190; AllianceGenome:HGNC:20996 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CIA-II Summary This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. [provided by RefSeq, Jul 2008] Expression Biased expression in testis (RPKM 18.2), lymph node (RPKM 12.4) and 13 other tissues See more Orthologs mouse all