PNOC, Official Symbol PNOCprovided by HGNC Official Full Name prepronociceptinprovided by HGNC Primary source HGNC:HGNC:9163 See related Ensembl:ENSG00000168081 MIM:601459; AllianceGenome:HGNC:9163 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOP; OFQ; N/OFQ; PPNOC; ppN/OFQ Summary This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally regulate body temperature, learning and memory, and hunger. Another product of the encoded preproprotein, nocistatin, may inhibit the effects of nociceptin. [provided by RefSeq, Jul 2015] Expression Biased expression in brain (RPKM 7.7), lymph node (RPKM 5.0) and 8 other tissues See more Orthologs mouse all