PROKR1, Official Symbol PROKR1provided by HGNC Official Full Name prokineticin receptor 1provided by HGNC Primary source HGNC:HGNC:4524 See related Ensembl:ENSG00000169618 MIM:607122; AllianceGenome:HGNC:4524 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZAQ; PKR1; GPR73; PK-R1; GPR73a Summary This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016] Expression Biased expression in fat (RPKM 1.4), adrenal (RPKM 0.7) and 2 other tissues See more Orthologs mouse all