VSIG4, Official Symbol VSIG4provided by HGNC Official Full Name V-set and immunoglobulin domain containing 4provided by HGNC Primary source HGNC:HGNC:17032 See related Ensembl:ENSG00000155659 MIM:300353; AllianceGenome:HGNC:17032 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRIg; Z39IG Summary This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Expression Broad expression in placenta (RPKM 50.4), lung (RPKM 39.9) and 19 other tissues See more Orthologs mouse all