USP36, Official Symbol USP36provided by HGNC Official Full Name ubiquitin specific peptidase 36provided by HGNC Primary source HGNC:HGNC:20062 See related Ensembl:ENSG00000055483 MIM:612543; AllianceGenome:HGNC:20062 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DUB1 Summary This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in bone marrow (RPKM 11.2), adrenal (RPKM 8.5) and 25 other tissues See more Orthologs mouse all