PTGDR, Official Symbol PTGDRprovided by HGNC Official Full Name prostaglandin D2 receptorprovided by HGNC Primary source HGNC:HGNC:9591 See related Ensembl:ENSG00000168229 MIM:604687; AllianceGenome:HGNC:9591 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DP; AS1; DP1; ASRT1; PTGDR1 Summary This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Broad expression in spleen (RPKM 1.6), colon (RPKM 1.3) and 19 other tissues See more Orthologs mouse all