PIK3CG, Official Symbol PIK3CGprovided by HGNC Official Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gammaprovided by HGNC Primary source HGNC:HGNC:8978 See related Ensembl:ENSG00000105851 MIM:601232; AllianceGenome:HGNC:8978 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PI3K; PIK3; IMD97; PI3CG; PI3Kgamma; p110gamma; p120-PI3K Summary Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015] Expression Broad expression in bone marrow (RPKM 12.4), lymph node (RPKM 9.1) and 18 other tissues See more Orthologs mouse all