KPNA7, Official Symbol KPNA7provided by HGNC Official Full Name karyopherin subunit alpha 7provided by HGNC Primary source HGNC:HGNC:21839 See related Ensembl:ENSG00000185467 MIM:614107; AllianceGenome:HGNC:21839 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IPOA8; OZEMA17 Summary The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import, but exhibits different nuclear localization signal binding specificity compared to other members of the family. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Jul 2016] Expression Biased expression in stomach (RPKM 1.6), gall bladder (RPKM 0.1) and 3 other tissues See more Orthologs mouse all