ABCB8, Official Symbol ABCB8provided by HGNC Official Full Name ATP binding cassette subfamily B member 8provided by HGNC Primary source HGNC:HGNC:49 See related Ensembl:ENSG00000197150 MIM:605464; AllianceGenome:HGNC:49 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MABC1; M-ABC1; MITOSUR; EST328128 Summary This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in testis (RPKM 5.6), endometrium (RPKM 5.4) and 25 other tissues See more Orthologs mouse all