EXOSC5, Official Symbol EXOSC5provided by HGNC Official Full Name exosome component 5provided by HGNC Primary source HGNC:HGNC:24662 See related Ensembl:ENSG00000077348 MIM:606492; AllianceGenome:HGNC:24662 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p12B; CABAC; RRP46; RRP41B; Rrp46p; hRrp46p Summary Predicted to enable RNA binding activity. Involved in DNA deamination and exonucleolytic catabolism of deadenylated mRNA. Acts upstream of or within defense response to virus. Located in nucleolus; nucleoplasm; and transcriptionally active chromatin. Part of exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 8.8), ovary (RPKM 8.2) and 25 other tissues See more Orthologs mouse all