KAT2A, Official Symbol KAT2Aprovided by HGNC Official Full Name lysine acetyltransferase 2Aprovided by HGNC Primary source HGNC:HGNC:4201 See related Ensembl:ENSG00000108773 MIM:602301; AllianceGenome:HGNC:4201 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GCN5; hGCN5; GCN5L2; PCAF-b Summary KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009] Expression Ubiquitous expression in ovary (RPKM 41.6), adrenal (RPKM 30.6) and 25 other tissues See more Orthologs mouse all