NQO2, Official Symbol NQO2provided by HGNC Official Full Name N-ribosyldihydronicotinamide:quinone dehydrogenase 2provided by HGNC Primary source HGNC:HGNC:7856 See related Ensembl:ENSG00000124588 MIM:160998; AllianceGenome:HGNC:7856 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as QR2; DHQV; DIA6; NMOR2 Summary This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] Expression Broad expression in kidney (RPKM 43.3), fat (RPKM 18.6) and 24 other tissues See more Orthologs mouse all