RAP1B, Official Symbol RAP1Bprovided by HGNC Official Full Name RAP1B, member of RAS oncogene familyprovided by HGNC Primary source HGNC:HGNC:9857 See related Ensembl:ENSG00000127314 MIM:179530; AllianceGenome:HGNC:9857 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K-REV; RAL1B Summary This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011] Expression Ubiquitous expression in lymph node (RPKM 83.8), appendix (RPKM 79.8) and 25 other tissues See more Orthologs mouse all