ABR, Official Symbol ABRprovided by HGNC Official Full Name ABR activator of RhoGEF and GTPaseprovided by HGNC Primary source HGNC:HGNC:81 See related Ensembl:ENSG00000159842 MIM:600365; AllianceGenome:HGNC:81 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MDB Summary This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in brain (RPKM 31.0), heart (RPKM 11.9) and 23 other tissues See more Orthologs mouse all