BRINP3, Official Symbol BRINP3provided by HGNC Official Full Name BMP/retinoic acid inducible neural specific 3provided by HGNC Primary source HGNC:HGNC:22393 See related Ensembl:ENSG00000162670 MIM:618390; AllianceGenome:HGNC:22393 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM5C; DBCCR1L; DBCCR1L1 Summary This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] Expression Biased expression in brain (RPKM 4.5), small intestine (RPKM 2.0) and 6 other tissues See more Orthologs mouse all