ICA1, Official Symbol ICA1provided by HGNC Official Full Name islet cell autoantigen 1provided by HGNC Primary source HGNC:HGNC:5343 See related Ensembl:ENSG00000003147 MIM:147625; AllianceGenome:HGNC:5343 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ICA69; ICAp69 Summary This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] Expression Ubiquitous expression in testis (RPKM 10.6), heart (RPKM 7.8) and 23 other tissues See more Orthologs mouse all