USP10, Official Symbol USP10provided by HGNC Official Full Name ubiquitin specific peptidase 10provided by HGNC Primary source HGNC:HGNC:12608 See related Ensembl:ENSG00000103194 MIM:609818; AllianceGenome:HGNC:12608 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBPO Summary Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013] Expression Ubiquitous expression in placenta (RPKM 15.2), lymph node (RPKM 13.4) and 25 other tissues See more Orthologs mouse all