NUDT4, Official Symbol NUDT4provided by HGNC Official Full Name nudix hydrolase 4provided by HGNC Primary source HGNC:HGNC:8051 See related Ensembl:ENSG00000173598 MIM:609229; AllianceGenome:HGNC:8051 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DIPP2; NUDT4B; DIPP-2B; HDCMB47P; DIPP2beta; DIPP2alpha Summary The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 30.0), kidney (RPKM 25.7) and 25 other tissues See more Orthologs mouse all