MAP1LC3A, Official Symbol MAP1LC3Aprovided by HGNC Official Full Name microtubule associated protein 1 light chain 3 alphaprovided by HGNC Primary source HGNC:HGNC:6838 See related Ensembl:ENSG00000101460 MIM:601242; AllianceGenome:HGNC:6838 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LC3; LC3A; ATG8E; MAP1ALC3; MAP1BLC3 Summary MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in brain (RPKM 31.2), fat (RPKM 18.3) and 25 other tissues See more Orthologs mouse all