FGD3, Official Symbol FGD3provided by HGNC Official Full Name FYVE, RhoGEF and PH domain containing 3provided by HGNC Primary source HGNC:HGNC:16027 See related Ensembl:ENSG00000127084 MIM:617554; AllianceGenome:HGNC:16027 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFYVE5 Summary Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 16.0), lymph node (RPKM 14.2) and 17 other tissues See more Orthologs mouse all