CLTC, Official Symbol CLTCprovided by HGNC Official Full Name clathrin heavy chainprovided by HGNC Primary source HGNC:HGNC:2092 See related Ensembl:ENSG00000141367 MIM:118955; AllianceGenome:HGNC:2092 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Hc; CHC; CHC17; MRD56; CLH-17; CLTCL2 Summary Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 67.0), thyroid (RPKM 49.4) and 25 other tissues See more Orthologs mouse all