HSPE1, Official Symbol HSPE1provided by HGNC Official Full Name heat shock protein family E (Hsp10) member 1provided by HGNC Primary source HGNC:HGNC:5269 See related Ensembl:ENSG00000115541 MIM:600141; AllianceGenome:HGNC:5269 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPF; CPN10; GROES; HSP10 Summary This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011] Expression Ubiquitous expression in adrenal (RPKM 184.7), kidney (RPKM 90.5) and 24 other tissues See more Orthologs mouse all