RAB3GAP1, Official Symbol RAB3GAP1provided by HGNC Official Full Name RAB3 GTPase activating protein catalytic subunit 1provided by HGNC Primary source HGNC:HGNC:17063 See related Ensembl:ENSG00000115839 MIM:602536; AllianceGenome:HGNC:17063 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P130; MARTS2; WARBM1; RAB3GAP; RAB3GAP130 Summary This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] Expression Ubiquitous expression in brain (RPKM 16.8), thyroid (RPKM 15.9) and 25 other tissues See more Orthologs mouse all