HOXA7, Official Symbol HOXA7provided by HGNC Official Full Name homeobox A7provided by HGNC Primary source HGNC:HGNC:5108 See related Ensembl:ENSG00000122592 MIM:142950; AllianceGenome:HGNC:5108 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANTP; HOX1; HOX1A; HOX1.1 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 9.4), adrenal (RPKM 7.6) and 14 other tissues See more Orthologs mouse all