GCKR, Official Symbol GCKRprovided by HGNC Official Full Name glucokinase regulatorprovided by HGNC Primary source HGNC:HGNC:4196 See related Ensembl:ENSG00000084734 MIM:600842; AllianceGenome:HGNC:4196 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GKRP; FGQTL5 Summary This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 19.0), stomach (RPKM 3.8) and 3 other tissues See more Orthologs mouse all