KCNE2, Official Symbol KCNE2provided by HGNC Official Full Name potassium voltage-gated channel subfamily E regulatory subunit 2provided by HGNC Primary source HGNC:HGNC:6242 See related Ensembl:ENSG00000159197 MIM:603796; AllianceGenome:HGNC:6242 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LQT5; LQT6; ATFB4; MIRP1 Summary Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008] Expression Biased expression in stomach (RPKM 72.9) and duodenum (RPKM 4.0) See more Orthologs mouse all