PRKDC, Official Symbol PRKDCprovided by HGNC Official Full Name protein kinase, DNA-activated, catalytic subunitprovided by HGNC Primary source HGNC:HGNC:9413 See related Ensembl:ENSG00000253729 MIM:600899; AllianceGenome:HGNC:9413 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HYRC; p350; DNAPK; DNPK1; HYRC1; IMD26; XRCC7; DNAPKc; DNA-PKC; DNA-PKcs Summary This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010] Expression Ubiquitous expression in testis (RPKM 10.8), lymph node (RPKM 10.6) and 25 other tissues See more Orthologs mouse all