LXN, Official Symbol LXNprovided by HGNC Official Full Name latexinprovided by HGNC Primary source HGNC:HGNC:13347 See related Ensembl:ENSG00000079257 MIM:609305; AllianceGenome:HGNC:13347 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ECI; TCI Summary This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation. [provided by RefSeq, Jul 2020] Expression Ubiquitous expression in ovary (RPKM 17.1), gall bladder (RPKM 15.4) and 24 other tissues See more Orthologs mouse all