DUSP14, Official Symbol DUSP14provided by HGNC Official Full Name dual specificity phosphatase 14provided by HGNC Primary source HGNC:HGNC:17007 See related Ensembl:ENSG00000276023 MIM:606618; AllianceGenome:HGNC:17007 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKP6; MKP-L Summary Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] Expression Broad expression in thyroid (RPKM 9.3), skin (RPKM 8.7) and 24 other tissues See more Orthologs mouse all