ADORA2B, Official Symbol ADORA2Bprovided by HGNC Official Full Name adenosine A2b receptorprovided by HGNC Primary source HGNC:HGNC:264 See related Ensembl:ENSG00000170425 MIM:600446; AllianceGenome:HGNC:264 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADORA2 Summary This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] Expression Broad expression in colon (RPKM 1.7), placenta (RPKM 1.2) and 17 other tissues See more Orthologs mouse all