SFRP2, Official Symbol SFRP2provided by HGNC Official Full Name secreted frizzled related protein 2provided by HGNC Primary source HGNC:HGNC:10777 See related Ensembl:ENSG00000145423 MIM:604157; AllianceGenome:HGNC:10777 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FRP-2; SARP1; SDF-5 Summary This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008] Expression Biased expression in urinary bladder (RPKM 276.9), gall bladder (RPKM 211.4) and 9 other tissues See more Orthologs mouse all