TINAG, Official Symbol TINAGprovided by HGNC Official Full Name tubulointerstitial nephritis antigenprovided by HGNC Primary source HGNC:HGNC:14599 See related Ensembl:ENSG00000137251 MIM:606749; AllianceGenome:HGNC:14599 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIN-AG Summary This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and temporal pattern throughout nephrogenesis. [provided by RefSeq, Nov 2011] Expression Biased expression in kidney (RPKM 36.8), colon (RPKM 4.4) and 2 other tissues See more Orthologs mouse all