ESM1, Official Symbol ESM1provided by HGNC Official Full Name endothelial cell specific molecule 1provided by HGNC Primary source HGNC:HGNC:3466 See related Ensembl:ENSG00000164283 MIM:601521; AllianceGenome:HGNC:3466 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as endocan Summary This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] Expression Biased expression in thyroid (RPKM 12.6), kidney (RPKM 8.9) and 9 other tissues See more Orthologs mouse all