RPH3AL, Official Symbol RPH3ALprovided by HGNC Official Full Name rabphilin 3A like (without C2 domains)provided by HGNC Primary source HGNC:HGNC:10296 See related Ensembl:ENSG00000181031 MIM:604881; AllianceGenome:HGNC:10296 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NOC2 Summary The protein encoded by this gene plays a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010] Expression Ubiquitous expression in spleen (RPKM 3.5), thyroid (RPKM 2.9) and 24 other tissues See more Orthologs mouse all