NELL2, Official Symbol NELL2provided by HGNC Official Full Name neural EGFL like 2provided by HGNC Primary source HGNC:HGNC:7751 See related Ensembl:ENSG00000184613 MIM:602320; AllianceGenome:HGNC:7751 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NRP2 Summary The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009] Expression Biased expression in brain (RPKM 55.4), duodenum (RPKM 9.0) and 5 other tissues See more Orthologs mouse all