XAGE2, Official Symbol XAGE2provided by HGNC Official Full Name X antigen family member 2provided by HGNC Primary source HGNC:HGNC:4112 See related Ensembl:ENSG00000155622 MIM:300416; AllianceGenome:HGNC:4112 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT12.2; GAGED3; XAGE-2; XAGE2B Summary This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq, Jul 2008] Expression Restricted expression toward placenta (RPKM 70.1) See more Orthologs all