CNIH2, Official Symbol CNIH2provided by HGNC Official Full Name cornichon family AMPA receptor auxiliary protein 2provided by HGNC Primary source HGNC:HGNC:28744 See related Ensembl:ENSG00000174871 MIM:611288; AllianceGenome:HGNC:28744 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Cnil; CNIH-2 Summary The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] Expression Biased expression in brain (RPKM 22.4), adrenal (RPKM 2.7) and 1 other tissue See more Orthologs mouse all