ZMIZ1, Official Symbol ZMIZ1provided by HGNC Official Full Name zinc finger MIZ-type containing 1provided by HGNC Primary source HGNC:HGNC:16493 See related Ensembl:ENSG00000108175 MIM:607159; AllianceGenome:HGNC:16493 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIZ; RAI17; ZIMP10; NEDDFSA; TRAFIP10 Summary This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010] Expression Ubiquitous expression in ovary (RPKM 21.7), spleen (RPKM 21.6) and 25 other tissues See more Orthologs mouse all