MRPS2, Official Symbol MRPS2provided by HGNC Official Full Name mitochondrial ribosomal protein S2provided by HGNC Primary source HGNC:HGNC:14495 See related Ensembl:ENSG00000122140 MIM:611971; AllianceGenome:HGNC:14495 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as S2mt; uS2m; CGI-91; MRP-S2; COXPD36 Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] Expression Ubiquitous expression in kidney (RPKM 13.4), ovary (RPKM 10.7) and 25 other tissues See more Orthologs mouse all