TRIM22, Official Symbol TRIM22provided by HGNC Official Full Name tripartite motif containing 22provided by HGNC Primary source HGNC:HGNC:16379 See related Ensembl:ENSG00000132274 MIM:606559; AllianceGenome:HGNC:16379 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNF94; STAF50; GPSTAF50 Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein is involved in innate immunity against different DNA and RNA viruses. [provided by RefSeq, Oct 2021] Expression Broad expression in spleen (RPKM 83.9), lymph node (RPKM 70.5) and 24 other tissues See more Orthologs all