HTR4, Official Symbol HTR4provided by HGNC Official Full Name 5-hydroxytryptamine receptor 4provided by HGNC Primary source HGNC:HGNC:5299 See related Ensembl:ENSG00000164270 MIM:602164; AllianceGenome:HGNC:5299 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 5-HT4; 5-HT4R Summary This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010] Expression Biased expression in small intestine (RPKM 2.1), duodenum (RPKM 1.1) and 5 other tissues See more Orthologs mouse all