UBE2E2, Official Symbol UBE2E2provided by HGNC Official Full Name ubiquitin conjugating enzyme E2 E2provided by HGNC Primary source HGNC:HGNC:12478 See related Ensembl:ENSG00000182247 MIM:602163; AllianceGenome:HGNC:12478 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBCH8 Summary Enables ISG15 transferase activity and ubiquitin conjugating enzyme activity. Involved in protein modification by small protein conjugation. Acts upstream of or within cellular response to DNA damage stimulus and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 1.5), fat (RPKM 1.2) and 25 other tissues See more Orthologs mouse all