EPHA5, Official Symbol EPHA5provided by HGNC Official Full Name EPH receptor A5provided by HGNC Primary source HGNC:HGNC:3389 See related Ensembl:ENSG00000145242 MIM:600004; AllianceGenome:HGNC:3389 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EK7; CEK7; EHK1; HEK7; EHK-1; TYRO4 Summary This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Aug 2013] Expression Biased expression in brain (RPKM 4.9), ovary (RPKM 1.0) and 6 other tissues See more Orthologs mouse all