PHIP, Official Symbol PHIPprovided by HGNC Official Full Name pleckstrin homology domain interacting proteinprovided by HGNC Primary source HGNC:HGNC:15673 See related Ensembl:ENSG00000146247 MIM:612870; AllianceGenome:HGNC:15673 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ndrp; BRWD2; DIDOD; WDR11; DCAF14; CHUJANS Summary This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. The encoded protein may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in bone marrow (RPKM 13.2), endometrium (RPKM 7.1) and 25 other tissues See more Orthologs mouse all