CA3, Official Symbol CA3provided by HGNC Official Full Name carbonic anhydrase 3provided by HGNC Primary source HGNC:HGNC:1374 See related Ensembl:ENSG00000164879 MIM:114750; AllianceGenome:HGNC:1374 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Car3; CAIII Summary Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008] Expression Biased expression in prostate (RPKM 78.7), fat (RPKM 38.8) and 3 other tissues See more Orthologs mouse all