NEDD8, Official Symbol NEDD8provided by HGNC Official Full Name NEDD8 ubiquitin like modifierprovided by HGNC Primary source HGNC:HGNC:7732 See related Ensembl:ENSG00000129559 MIM:603171; AllianceGenome:HGNC:7732 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NEDD-8 Summary Enables ubiquitin protein ligase binding activity. Acts upstream of or within protein neddylation. Located in cytosol and nucleoplasm. Biomarker of Parkinson's disease and malignant astrocytoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 81.8), kidney (RPKM 81.6) and 25 other tissues See more Orthologs mouse all