CYP4F2, Official Symbol CYP4F2provided by HGNC Official Full Name cytochrome P450 family 4 subfamily F member 2provided by HGNC Primary source HGNC:HGNC:2645 See related Ensembl:ENSG00000186115 MIM:604426; AllianceGenome:HGNC:2645 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPF2 Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 63.5), small intestine (RPKM 42.7) and 2 other tissues See more