CLTA, Official Symbol CLTAprovided by HGNC Official Full Name clathrin light chain Aprovided by HGNC Primary source HGNC:HGNC:2090 See related Ensembl:ENSG00000122705 MIM:118960; AllianceGenome:HGNC:2090 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LCA Summary Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, May 2010] Expression Ubiquitous expression in colon (RPKM 66.3), kidney (RPKM 59.1) and 25 other tissues See more Orthologs mouse all