HAS3, Official Symbol HAS3provided by HGNC Official Full Name hyaluronan synthase 3provided by HGNC Primary source HGNC:HGNC:4820 See related Ensembl:ENSG00000103044 MIM:602428; AllianceGenome:HGNC:4820 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] Expression Broad expression in urinary bladder (RPKM 19.2), lung (RPKM 12.8) and 24 other tissues See more Orthologs mouse all