PPIP5K2, Official Symbol PPIP5K2provided by HGNC Official Full Name diphosphoinositol pentakisphosphate kinase 2provided by HGNC Primary source HGNC:HGNC:29035 See related Ensembl:ENSG00000145725 MIM:611648; AllianceGenome:HGNC:29035 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VIP2; IP7K2; CFAP160; DFNB100; HISPPD1 Summary This gene encodes a member of the histidine acid phosphatase family of proteins. Despite containing a histidine acid phosphatase domain, the encoded protein functions as an inositol pyrophosphate kinase, and is thought to lack phosphatase activity. This kinase activity is the mechanism by which the encoded protein synthesizes high-energy inositol pyrophosphates, which act as signaling molecules that regulate cellular homeostasis and other processes. This gene may be associated with autism spectrum disorder in human patients. [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in bone marrow (RPKM 8.5), colon (RPKM 7.8) and 25 other tissues See more Orthologs mouse all