SHANK1, Official Symbol SHANK1provided by HGNC Official Full Name SH3 and multiple ankyrin repeat domains 1provided by HGNC Primary source HGNC:HGNC:15474 See related Ensembl:ENSG00000161681 MIM:604999; AllianceGenome:HGNC:15474 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SSTRIP; SPANK-1; synamon Summary This gene encodes a member of the SHANK (SH3 domain and ankyrin repeat containing) family of proteins. Members of this family act as scaffold proteins that are required for the development and function of neuronal synapses. Deletions in this gene may be associated with autism spectrum disorder in males. [provided by RefSeq, Apr 2016] Expression Biased expression in brain (RPKM 17.7) and adrenal (RPKM 0.7) See more Orthologs mouse all