ADAM10, Official Symbol ADAM10provided by HGNC Official Full Name ADAM metallopeptidase domain 10provided by HGNC Primary source HGNC:HGNC:188 See related Ensembl:ENSG00000137845 MIM:602192; AllianceGenome:HGNC:188 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RAK; kuz; AD10; AD18; MADM; CD156c; CDw156; HsT18717 Summary Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016] Expression Ubiquitous expression in urinary bladder (RPKM 30.9), thyroid (RPKM 26.8) and 25 other tissues See more Orthologs mouse all