FN3KRP, Official Symbol FN3KRPprovided by HGNC Official Full Name fructosamine 3 kinase related proteinprovided by HGNC Primary source HGNC:HGNC:25700 See related Ensembl:ENSG00000141560 MIM:611683; AllianceGenome:HGNC:25700 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FN3KL Summary A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012] Expression Ubiquitous expression in brain (RPKM 19.2), fat (RPKM 14.3) and 25 other tissues See more Orthologs mouse all