MED21, Official Symbol MED21provided by HGNC Official Full Name mediator complex subunit 21provided by HGNC Primary source HGNC:HGNC:11473 See related Ensembl:ENSG00000152944 MIM:603800; AllianceGenome:HGNC:11473 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SRB7; SURB7; hSrb7 Summary This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] Expression Ubiquitous expression in adrenal (RPKM 13.1), testis (RPKM 11.0) and 25 other tissues See more Orthologs mouse all