PLPPR5, Official Symbol PLPPR5provided by HGNC Official Full Name phospholipid phosphatase related 5provided by HGNC Primary source HGNC:HGNC:31703 See related Ensembl:ENSG00000117598 MIM:617287; AllianceGenome:HGNC:31703 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAP2; PRG5; LPPR5; PAP2D Summary The protein encoded by this gene is a type 2 member of the phosphatidic acid phosphatase (PAP) family. All type 2 members of this protein family contain 6 transmembrane regions, and a consensus N-glycosylation site. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 3.8), testis (RPKM 1.2) and 1 other tissue See more Orthologs mouse all