LPCAT1, Official Symbol LPCAT1provided by HGNC Official Full Name lysophosphatidylcholine acyltransferase 1provided by HGNC Primary source HGNC:HGNC:25718 See related Ensembl:ENSG00000153395 MIM:610472; AllianceGenome:HGNC:25718 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AYTL2; lpcat; AGPAT9; LPLAT8; PFAAP3; AGPAT10; LPCAT-1; lysoPAFAT Summary This gene encodes a member of the 1-acyl-sn-glycerol-3-phosphate acyltransferase family of proteins. The encoded enzyme plays a role in phospholipid metabolism, specifically in the conversion of lysophosphatidylcholine to phosphatidylcholine in the presence of acyl-CoA. This process is important in the synthesis of lung surfactant and platelet-activating factor (PAF). Elevated expression of this gene may contribute to the progression of oral squamous cell, prostate, breast, and other human cancers. [provided by RefSeq, Sep 2016] Expression Broad expression in lung (RPKM 73.0), spleen (RPKM 32.6) and 18 other tissues See more Orthologs mouse all