CCN2, Official Symbol CCN2provided by HGNC Official Full Name cellular communication network factor 2provided by HGNC Primary source HGNC:HGNC:2500 See related Ensembl:ENSG00000118523 MIM:121009; AllianceGenome:HGNC:2500 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CTGF; NOV2; HCS24; IBP-8; IGFBP8 Summary The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009] Expression Broad expression in spleen (RPKM 355.2), gall bladder (RPKM 303.1) and 21 other tissues See more Orthologs mouse all