PSRC1, Official Symbol PSRC1provided by HGNC Official Full Name proline and serine rich coiled-coil 1provided by HGNC Primary source HGNC:HGNC:24472 See related Ensembl:ENSG00000134222 MIM:613126; AllianceGenome:HGNC:24472 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DDA3; FP3214 Summary This gene encodes a proline-rich protein that is a target for regulation by the tumor suppressor protein p53. The encoded protein plays an important role in mitosis by recruiting and regulating microtubule depolymerases that destabalize microtubules. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Apr 2014] Expression Broad expression in brain (RPKM 9.0), testis (RPKM 4.6) and 23 other tissues See more Orthologs mouse all