HACL1, Official Symbol HACL1provided by HGNC Official Full Name 2-hydroxyacyl-CoA lyase 1provided by HGNC Primary source HGNC:HGNC:17856 See related Ensembl:ENSG00000131373 MIM:604300; AllianceGenome:HGNC:17856 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPCL; HPCL2; PHYH2; 2-HPCL Summary Enables several functions, including 2-hydroxy-3-methylhexadecanoyl-CoA lyase activity; ATP binding activity; and cation binding activity. Involved in fatty acid alpha-oxidation; phytanic acid metabolic process; and protein targeting to peroxisome. Located in nucleoplasm and peroxisome. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in duodenum (RPKM 25.3), testis (RPKM 14.8) and 25 other tissues See more Orthologs mouse all