RAB23, Official Symbol RAB23provided by HGNC Official Full Name RAB23, member RAS oncogene familyprovided by HGNC Primary source HGNC:HGNC:14263 See related Ensembl:ENSG00000112210 MIM:606144; AllianceGenome:HGNC:14263 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSPC137 Summary This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Broad expression in endometrium (RPKM 23.9), urinary bladder (RPKM 18.7) and 20 other tissues See more Orthologs mouse all