CTDP1, Official Symbol CTDP1provided by HGNC Official Full Name CTD phosphatase subunit 1provided by HGNC Primary source HGNC:HGNC:2498 See related Ensembl:ENSG00000060069 MIM:604927; AllianceGenome:HGNC:2498 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FCP1; CCFDN Summary This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] Expression Ubiquitous expression in testis (RPKM 8.7), colon (RPKM 6.0) and 25 other tissues See more Orthologs mouse all