CEP112, Official Symbol CEP112provided by HGNC Official Full Name centrosomal protein 112provided by HGNC Primary source HGNC:HGNC:28514 See related Ensembl:ENSG00000154240 MIM:618980; AllianceGenome:HGNC:28514 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCDC46; MACOCO; SPGF44 Summary This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] Expression Broad expression in testis (RPKM 4.7), fat (RPKM 2.6) and 20 other tissues See more Orthologs mouse all