AP1G2, Official Symbol AP1G2provided by HGNC Official Full Name adaptor related protein complex 1 subunit gamma 2provided by HGNC Primary source HGNC:HGNC:556 See related Ensembl:ENSG00000213983 MIM:603534; AllianceGenome:HGNC:556 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G2AD Summary Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. [provided by RefSeq, Aug 2017] Expression Ubiquitous expression in skin (RPKM 20.0), lymph node (RPKM 17.8) and 25 other tissues See more Orthologs mouse all