HOXB7, Official Symbol HOXB7provided by HGNC Official Full Name homeobox B7provided by HGNC Primary source HGNC:HGNC:5118 See related Ensembl:ENSG00000260027 MIM:142962; AllianceGenome:HGNC:5118 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX2; HOX2C; HHO.C1; Hox-2.3 Summary This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 10.0), colon (RPKM 8.7) and 15 other tissues See more Orthologs mouse all