ITGB6, Official Symbol ITGB6provided by HGNC Official Full Name integrin subunit beta 6provided by HGNC Primary source HGNC:HGNC:6161 See related Ensembl:ENSG00000115221 MIM:147558; AllianceGenome:HGNC:6161 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AI1H Summary This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Biased expression in lung (RPKM 25.8), urinary bladder (RPKM 17.2) and 12 other tissues See more Orthologs mouse all