SLC39A8, Official Symbol SLC39A8provided by HGNC Official Full Name solute carrier family 39 member 8provided by HGNC Primary source HGNC:HGNC:20862 See related Ensembl:ENSG00000138821 MIM:608732; AllianceGenome:HGNC:20862 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZIP8; CDG2N; PP3105; BIGM103; LZT-Hs6 Summary This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008] Expression Biased expression in lung (RPKM 46.9), colon (RPKM 11.2) and 13 other tissues See more Orthologs mouse all