GALR1, Official Symbol GALR1provided by HGNC Official Full Name galanin receptor 1provided by HGNC Primary source HGNC:HGNC:4132 See related Ensembl:ENSG00000166573 MIM:600377; AllianceGenome:HGNC:4132 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GALNR; GALNR1 Summary The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008] Expression Biased expression in adrenal (RPKM 1.2), brain (RPKM 0.7) and 7 other tissues See more Orthologs mouse all