SLC18A1, Official Symbol SLC18A1provided by HGNC Official Full Name solute carrier family 18 member A1provided by HGNC Primary source HGNC:HGNC:10934 See related Ensembl:ENSG00000036565 MIM:193002; AllianceGenome:HGNC:10934 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CGAT; VAT1; VMAT1 Summary The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008] Expression Biased expression in adrenal (RPKM 13.1), colon (RPKM 1.0) and 1 other tissue See more Orthologs mouse all