DENR, Official Symbol DENRprovided by HGNC Official Full Name density regulated re-initiation and release factorprovided by HGNC Primary source HGNC:HGNC:2769 See related Ensembl:ENSG00000139726 MIM:604550; AllianceGenome:HGNC:2769 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DRP; DRP1; SMAP-3 Summary This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 16.4), lymph node (RPKM 16.3) and 25 other tissues See more Orthologs mouse all