CORO2A, Official Symbol CORO2Aprovided by HGNC Official Full Name coronin 2Aprovided by HGNC Primary source HGNC:HGNC:2255 See related Ensembl:ENSG00000106789 MIM:602159; AllianceGenome:HGNC:2255 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IR10; WDR2; CLIPINB Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] Expression Broad expression in small intestine (RPKM 15.5), duodenum (RPKM 14.7) and 16 other tissues See more Orthologs mouse all