ERP27, Official Symbol ERP27provided by HGNC Official Full Name endoplasmic reticulum protein 27provided by HGNC Primary source HGNC:HGNC:26495 See related Ensembl:ENSG00000139055 MIM:610642; AllianceGenome:HGNC:26495 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PDIA8; C12orf46 Summary This gene encodes a noncatalytic member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. The canonical protein has an N-terminal signal sequence, two thioredoxin (TRX)-like domains and a C-terminal ER-retention sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which lack domains present in the canonical protein. [provided by RefSeq, Dec 2016] Expression Biased expression in pancreas (RPKM 211.6) and urinary bladder (RPKM 10.4) See more Orthologs mouse all