MSC, Official Symbol MSCprovided by HGNC Official Full Name musculinprovided by HGNC Primary source HGNC:HGNC:7321 See related Ensembl:ENSG00000178860 MIM:603628; AllianceGenome:HGNC:7321 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ABF1; MYOR; ABF-1; bHLHa22 Summary The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008] Expression Broad expression in placenta (RPKM 12.2), gall bladder (RPKM 7.2) and 23 other tissues See more Orthologs mouse all