RGL4, Official Symbol RGL4provided by HGNC Official Full Name ral guanine nucleotide dissociation stimulator like 4provided by HGNC Primary source HGNC:HGNC:31911 See related Ensembl:ENSG00000159496 MIM:612214; AllianceGenome:HGNC:31911 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Rgr Summary This oncogene encodes a protein similar to guanine nucleotide exchange factor Ral guanine dissociation stimulator. Increased expression of this gene leads to translocation of the encoded protein to the cell membrane. The encoded protein can activate several pathways, including the Ras-Raf-MEK-ERK cascade. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in bone marrow (RPKM 20.9), appendix (RPKM 6.7) and 23 other tissues See more Orthologs all