GNAO1, Official Symbol GNAO1provided by HGNC Official Full Name G protein subunit alpha o1provided by HGNC Primary source HGNC:HGNC:4389 See related Ensembl:ENSG00000087258 MIM:139311; AllianceGenome:HGNC:4389 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GNAO; HG1G; DEE17; NEDIM; EIEE17; HLA-DQB1; G-ALPHA-o Summary The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] Expression Biased expression in brain (RPKM 43.5), testis (RPKM 4.7) and 2 other tissues See more Orthologs mouse all