GDAP1L1, Official Symbol GDAP1L1provided by HGNC Official Full Name ganglioside induced differentiation associated protein 1 like 1provided by HGNC Primary source HGNC:HGNC:4213 See related Ensembl:ENSG00000124194 AllianceGenome:HGNC:4213 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dJ881L22.1; dJ995J12.1.1 Summary The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012] Expression Biased expression in brain (RPKM 7.9), adrenal (RPKM 0.4) and 1 other tissue See more Orthologs mouse all