DELE1, Official Symbol DELE1provided by HGNC Official Full Name DAP3 binding cell death enhancer 1provided by HGNC Primary source HGNC:HGNC:28969 See related Ensembl:ENSG00000081791 MIM:615741; AllianceGenome:HGNC:28969 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DELE; DELE1(L); KIAA0141 Summary Enables protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in HRI-mediated signaling; extrinsic apoptotic signaling pathway via death domain receptors; and regulation of cysteine-type endopeptidase activity involved in apoptotic process. Located in cytosol and mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in heart (RPKM 16.6), spleen (RPKM 16.6) and 25 other tissues See more Orthologs mouse all