ARHGEF5, Official Symbol ARHGEF5provided by HGNC Official Full Name Rho guanine nucleotide exchange factor 5provided by HGNC Primary source HGNC:HGNC:13209 See related Ensembl:ENSG00000050327 MIM:600888; AllianceGenome:HGNC:13209 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P60; TIM; GEF5; TIM1 Summary Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008] Expression Broad expression in thyroid (RPKM 23.4), skin (RPKM 15.6) and 23 other tissues See more Orthologs mouse all