DCTN5, Official Symbol DCTN5provided by HGNC Official Full Name dynactin subunit 5provided by HGNC Primary source HGNC:HGNC:24594 See related Ensembl:ENSG00000166847 MIM:612962; AllianceGenome:HGNC:24594 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] Expression Ubiquitous expression in brain (RPKM 13.0), testis (RPKM 7.5) and 25 other tissues See more Orthologs mouse all