NTF4, Official Symbol NTF4provided by HGNC Official Full Name neurotrophin 4provided by HGNC Primary source HGNC:HGNC:8024 See related Ensembl:ENSG00000225950 MIM:162662; AllianceGenome:HGNC:8024 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5 Summary This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008] Expression Biased expression in skin (RPKM 4.5), prostate (RPKM 2.1) and 6 other tissues See more Orthologs mouse all