PITX3, Official Symbol PITX3provided by HGNC Official Full Name paired like homeodomain 3provided by HGNC Primary source HGNC:HGNC:9006 See related Ensembl:ENSG00000107859 MIM:602669; AllianceGenome:HGNC:9006 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ASMD; ASOD; PTX3; ASGD1; CTPP4; CTRCT11 Summary This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all