HEG1, Official Symbol HEG1provided by HGNC Official Full Name heart development protein with EGF like domains 1provided by HGNC Primary source HGNC:HGNC:29227 See related Ensembl:ENSG00000173706 MIM:614182; AllianceGenome:HGNC:29227 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEG; MST112; MSTP112 Summary Predicted to enable calcium ion binding activity. Involved in several processes, including negative regulation of Rho protein signal transduction; negative regulation of Rho-dependent protein serine/threonine kinase activity; and negative regulation of membrane permeability. Located in cell-cell junction. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 26.8), lung (RPKM 26.7) and 23 other tissues See more Orthologs mouse all