TCTN2, Official Symbol TCTN2provided by HGNC Official Full Name tectonic family member 2provided by HGNC Primary source HGNC:HGNC:25774 See related Ensembl:ENSG00000168778 MIM:613846; AllianceGenome:HGNC:25774 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MKS8; TECT2; JBTS24; C12orf38 Summary This gene encodes a type I membrane protein that belongs to the tectonic family. Studies in mice suggest that this protein may be involved in hedgehog signaling, and essential for ciliogenesis. Mutations in this gene are associated with Meckel syndrome type 8. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Expression Broad expression in testis (RPKM 7.3), thyroid (RPKM 7.3) and 25 other tissues See more Orthologs mouse all