FOXA2, Official Symbol FOXA2provided by HGNC Official Full Name forkhead box A2provided by HGNC Primary source HGNC:HGNC:5022 See related Ensembl:ENSG00000125798 MIM:600288; AllianceGenome:HGNC:5022 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNF3B; TCF3B; HNF-3-beta Summary This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008] Expression Biased expression in stomach (RPKM 15.2), lung (RPKM 9.0) and 8 other tissues See more Orthologs mouse all