PRPS1L1, Official Symbol PRPS1L1provided by HGNC Official Full Name phosphoribosyl pyrophosphate synthetase 1 like 1provided by HGNC Primary source HGNC:HGNC:9463 See related Ensembl:ENSG00000229937 MIM:611566; AllianceGenome:HGNC:9463 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRPS1; PRPS3; PRPSL; PRS-III Summary This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq, Jul 2008] Orthologs mouse all