MEGF10, Official Symbol MEGF10provided by HGNC Official Full Name multiple EGF like domains 10provided by HGNC Primary source HGNC:HGNC:29634 See related Ensembl:ENSG00000145794 MIM:612453; AllianceGenome:HGNC:29634 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SR-F3; EMARDD; CMYP10A; CMYP10B Summary This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012] Expression Biased expression in brain (RPKM 5.7), adrenal (RPKM 1.0) and 4 other tissues See more Orthologs mouse all