GPR85, Official Symbol GPR85provided by HGNC Official Full Name G protein-coupled receptor 85provided by HGNC Primary source HGNC:HGNC:4536 See related Ensembl:ENSG00000164604 MIM:605188; AllianceGenome:HGNC:4536 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SREB; SREB2 Summary Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008] Expression Biased expression in brain (RPKM 3.3), testis (RPKM 1.1) and 12 other tissues See more Orthologs mouse all