ANGPT4, Official Symbol ANGPT4provided by HGNC Official Full Name angiopoietin 4provided by HGNC Primary source HGNC:HGNC:487 See related Ensembl:ENSG00000101280 MIM:603705; AllianceGenome:HGNC:487 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANG3; ANG4 Summary Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008] Expression Biased expression in fat (RPKM 1.7), ovary (RPKM 1.2) and 11 other tissues See more Orthologs mouse all