TPX2, Official Symbol TPX2provided by HGNC Official Full Name TPX2 microtubule nucleation factorprovided by HGNC Primary source HGNC:HGNC:1249 See related Ensembl:ENSG00000088325 MIM:605917; AllianceGenome:HGNC:1249 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1 Summary Enables importin-alpha family protein binding activity and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; mitotic spindle; and nucleoplasm. Colocalizes with spindle pole. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 19.8), bone marrow (RPKM 18.0) and 16 other tissues See more Orthologs mouse all