GGTLC1, Official Symbol GGTLC1provided by HGNC Official Full Name gamma-glutamyltransferase light chain 1provided by HGNC Primary source HGNC:HGNC:16437 See related Ensembl:ENSG00000149435 MIM:612338; AllianceGenome:HGNC:16437 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GGTL6; GGTLA3; GGTLA4; dJ831C21.1; dJ831C21.2 Summary This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008] Expression Biased expression in lung (RPKM 7.4), testis (RPKM 4.4) and 6 other tissues See more Orthologs all