LRRN2, Official Symbol LRRN2provided by HGNC Official Full Name leucine rich repeat neuronal 2provided by HGNC Primary source HGNC:HGNC:16914 See related Ensembl:ENSG00000170382 MIM:605492; AllianceGenome:HGNC:16914 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAC1; LRRN5; LRANK1; FIGLER7 Summary The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 5.5), kidney (RPKM 2.6) and 20 other tissues See more Orthologs mouse all