ADAM8, Official Symbol ADAM8provided by HGNC Official Full Name ADAM metallopeptidase domain 8provided by HGNC Primary source HGNC:HGNC:215 See related Ensembl:ENSG00000151651 MIM:602267; AllianceGenome:HGNC:215 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MS2; CD156; CD156a Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009] Expression Biased expression in bone marrow (RPKM 22.3), spleen (RPKM 13.4) and 12 other tissues See more Orthologs mouse all