GLO1, Official Symbol GLO1provided by HGNC Official Full Name glyoxalase Iprovided by HGNC Primary source HGNC:HGNC:4323 See related Ensembl:ENSG00000124767 MIM:138750; AllianceGenome:HGNC:4323 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLYI; GLOD1; HEL-S-74 Summary The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in prostate (RPKM 115.6), duodenum (RPKM 59.9) and 24 other tissues See more Orthologs mouse all