ATP23, Official Symbol ATP23provided by HGNC Official Full Name ATP23 metallopeptidase and ATP synthase assembly factor homologprovided by HGNC Primary source HGNC:HGNC:29452 See related Ensembl:ENSG00000166896 MIM:619760; AllianceGenome:HGNC:29452 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KUB3; XRCC6BP1 Summary The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016] Expression Broad expression in testis (RPKM 13.5), bone marrow (RPKM 4.5) and 24 other tissues See more Orthologs mouse all