PLIN3, Official Symbol PLIN3provided by HGNC Official Full Name perilipin 3provided by HGNC Primary source HGNC:HGNC:16893 See related Ensembl:ENSG00000105355 MIM:602702; AllianceGenome:HGNC:16893 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP17; TIP47; M6PRBP1 Summary Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2009] Expression Ubiquitous expression in esophagus (RPKM 42.9), small intestine (RPKM 31.3) and 24 other tissues See more Orthologs mouse all