ENPP7, Official Symbol ENPP7provided by HGNC Official Full Name ectonucleotide pyrophosphatase/phosphodiesterase 7provided by HGNC Primary source HGNC:HGNC:23764 See related Ensembl:ENSG00000182156 MIM:616997; AllianceGenome:HGNC:23764 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPP7; NPP-7; E-NPP 7; ALK-SMase Summary The protein encoded by this gene is an intestinal alkaline sphingomyelin phosphodiesterase that converts sphingomyelin to ceramide and phosphocholine. The encoded protein is anchored in the cell membrane, and it may function to protect the intestinal mucosa from inflammation and tumorigenesis. This protein is glycosylated and also exhibits lysophosphatidylcholine hydrolase activity. [provided by RefSeq, Oct 2016] Expression Biased expression in small intestine (RPKM 36.1), duodenum (RPKM 15.1) and 1 other tissue See more Orthologs mouse all