CBX8, Official Symbol CBX8provided by HGNC Official Full Name chromobox 8provided by HGNC Primary source HGNC:HGNC:15962 See related Ensembl:ENSG00000141570 MIM:617354; AllianceGenome:HGNC:15962 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PC3; RC1 Summary Enables methylated histone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in chromatin and nucleoplasm. Part of PRC1 complex. Biomarker of esophagus squamous cell carcinoma and glioblastoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 4.1), placenta (RPKM 2.1) and 25 other tissues See more Orthologs mouse all