RNF4, Official Symbol RNF4provided by HGNC Official Full Name ring finger protein 4provided by HGNC Primary source HGNC:HGNC:10067 See related Ensembl:ENSG00000063978 MIM:602850; AllianceGenome:HGNC:10067 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SLX5; SNURF; RES4-26 Summary The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010] Expression Ubiquitous expression in lymph node (RPKM 20.6), testis (RPKM 19.4) and 25 other tissues See more Orthologs mouse all