CLIC3, Official Symbol CLIC3provided by HGNC Official Full Name chloride intracellular channel 3provided by HGNC Primary source HGNC:HGNC:2064 See related Ensembl:ENSG00000169583 MIM:606533; AllianceGenome:HGNC:2064 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. [provided by RefSeq, Jul 2008] Expression Biased expression in esophagus (RPKM 23.8), thyroid (RPKM 21.4) and 5 other tissues See more Orthologs mouse all