RGS21, Official Symbol RGS21provided by HGNC Official Full Name regulator of G protein signaling 21provided by HGNC Primary source HGNC:HGNC:26839 See related Ensembl:ENSG00000253148 MIM:612407; AllianceGenome:HGNC:26839 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM, Nov 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all