OIP5, Official Symbol OIP5provided by HGNC Official Full Name Opa interacting protein 5provided by HGNC Primary source HGNC:HGNC:20300 See related Ensembl:ENSG00000104147 MIM:606020; AllianceGenome:HGNC:20300 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT86; MIS18B; LINT-25; MIS18beta; hMIS18beta; 5730547N13Rik Summary The protein encoded by this gene localizes to centromeres, where it is essential for recruitment of CENP-A through the mediator Holliday junction recognition protein. Expression of this gene is upregulated in several cancers, making it a putative therapeutic target. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] Expression Biased expression in testis (RPKM 12.1), bone marrow (RPKM 3.3) and 11 other tissues See more Orthologs mouse all