SLC7A7, Official Symbol SLC7A7provided by HGNC Official Full Name solute carrier family 7 member 7provided by HGNC Primary source HGNC:HGNC:11065 See related Ensembl:ENSG00000155465 MIM:603593; AllianceGenome:HGNC:11065 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LPI; LAT3; MOP-2; Y+LAT1; y+LAT-1 Summary The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011] Expression Biased expression in kidney (RPKM 96.7), small intestine (RPKM 45.3) and 11 other tissues See more Orthologs mouse all