KCNT1, Official Symbol KCNT1provided by HGNC Official Full Name potassium sodium-activated channel subfamily T member 1provided by HGNC Primary source HGNC:HGNC:18865 See related Ensembl:ENSG00000107147 MIM:608167; AllianceGenome:HGNC:18865 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEE14; ENFL5; SLACK; EIEE14; KCa4.1; Slo2.2; bA100C15.2 Summary Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] Expression Biased expression in brain (RPKM 4.3), spleen (RPKM 2.1) and 2 other tissues See more Orthologs mouse all