PIM3, Official Symbol PIM3provided by HGNC Official Full Name Pim-3 proto-oncogene, serine/threonine kinaseprovided by HGNC Primary source HGNC:HGNC:19310 See related Ensembl:ENSG00000198355 MIM:610580; AllianceGenome:HGNC:19310 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as pim-3 Summary The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis. [provided by RefSeq, Jun 2012] Expression Ubiquitous expression in bone marrow (RPKM 36.0), stomach (RPKM 21.6) and 25 other tissues See more Orthologs mouse all