CA5A, Official Symbol CA5Aprovided by HGNC Official Full Name carbonic anhydrase 5Aprovided by HGNC Primary source HGNC:HGNC:1377 See related Ensembl:ENSG00000174990 MIM:114761; AllianceGenome:HGNC:1377 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CA5; CAV; CAVA; CA5AD; GS1-21A4.1 Summary Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008] Expression Restricted expression toward liver (RPKM 2.8) See more Orthologs mouse all