BRK1, Official Symbol BRK1provided by HGNC Official Full Name BRICK1 subunit of SCAR/WAVE actin nucleating complexprovided by HGNC Primary source HGNC:HGNC:23057 See related Ensembl:ENSG00000254999 MIM:611183; AllianceGenome:HGNC:23057 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MDS027; hHBrk1; C3orf10; HSPC300 Summary Enables identical protein binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction and positive regulation of cellular component organization. Located in extracellular exosome. Part of SCAR complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 95.9), kidney (RPKM 81.0) and 25 other tissues See more Orthologs mouse all