DHODH, Official Symbol DHODHprovided by HGNC Official Full Name dihydroorotate dehydrogenase (quinone)provided by HGNC Primary source HGNC:HGNC:2867 See related Ensembl:ENSG00000102967 MIM:126064; AllianceGenome:HGNC:2867 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as URA1; POADS; DHOdehase Summary The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in liver (RPKM 7.8), kidney (RPKM 1.7) and 24 other tissues See more Orthologs mouse all