SCN3A, Official Symbol SCN3Aprovided by HGNC Official Full Name sodium voltage-gated channel alpha subunit 3provided by HGNC Primary source HGNC:HGNC:10590 See related Ensembl:ENSG00000153253 MIM:182391; AllianceGenome:HGNC:10590 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAC3; DEE62; EIEE62; FFEVF4; Nav1.3 Summary Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 5.7), adrenal (RPKM 1.1) and 11 other tissues See more Orthologs mouse all