BMPER, Official Symbol BMPERprovided by HGNC Official Full Name BMP binding endothelial regulatorprovided by HGNC Primary source HGNC:HGNC:24154 See related Ensembl:ENSG00000164619 MIM:608699; AllianceGenome:HGNC:24154 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CV2; CV-2; CRIM3 Summary This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011] Expression Broad expression in prostate (RPKM 4.5), brain (RPKM 3.2) and 19 other tissues See more Orthologs mouse all