PMM1, Official Symbol PMM1provided by HGNC Official Full Name phosphomannomutase 1provided by HGNC Primary source HGNC:HGNC:9114 See related Ensembl:ENSG00000100417 MIM:601786; AllianceGenome:HGNC:9114 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PMM 1; Sec53; PMMH-22 Summary Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 25.6), ovary (RPKM 25.1) and 25 other tissues See more Orthologs mouse all