ZP2, Official Symbol ZP2provided by HGNC Official Full Name zona pellucida glycoprotein 2provided by HGNC Primary source HGNC:HGNC:13188 See related Ensembl:ENSG00000103310 MIM:182888; AllianceGenome:HGNC:13188 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZPA; Zp-2; OOMD6; OZEMA6 Summary The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed of three glycoproteins with various functions during fertilization and preimplantation development. The glycosylated mature peptide is one of the structural components of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. Female mice lacking this gene do not form a stable zona matrix and are sterile. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] Expression Low expression observed in reference dataset See more Orthologs mouse all