PRSS16, Official Symbol PRSS16provided by HGNC Official Full Name serine protease 16provided by HGNC Primary source HGNC:HGNC:9480 See related Ensembl:ENSG00000112812 MIM:607169; AllianceGenome:HGNC:9480 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TSSP Summary This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008] Expression Broad expression in thyroid (RPKM 6.8), stomach (RPKM 3.4) and 17 other tissues See more Orthologs mouse all