TIMM8B, Official Symbol TIMM8Bprovided by HGNC Official Full Name translocase of inner mitochondrial membrane 8 homolog Bprovided by HGNC Primary source HGNC:HGNC:11818 See related Ensembl:ENSG00000150779 MIM:606659; AllianceGenome:HGNC:11818 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DDP2; TIM8B Summary This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.[provided by RefSeq, Aug 2009] Expression Ubiquitous expression in heart (RPKM 16.7), colon (RPKM 15.7) and 25 other tissues See more Orthologs mouse all