TPBG, Official Symbol TPBGprovided by HGNC Official Full Name trophoblast glycoproteinprovided by HGNC Primary source HGNC:HGNC:12004 See related Ensembl:ENSG00000146242 MIM:190920; AllianceGenome:HGNC:12004 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 5T4; M6P1; 5T4AG; WAIF1 Summary This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in esophagus (RPKM 8.0), endometrium (RPKM 5.0) and 22 other tissues See more Orthologs mouse all