BRD1, Official Symbol BRD1provided by HGNC Official Full Name bromodomain containing 1provided by HGNC Primary source HGNC:HGNC:1102 See related Ensembl:ENSG00000100425 MIM:604589; AllianceGenome:HGNC:1102 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BRL; BRPF1; BRPF2 Summary This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schizophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017] Expression Broad expression in testis (RPKM 11.6), bone marrow (RPKM 4.4) and 25 other tissues See more Orthologs mouse all