FCN1, Official Symbol FCN1provided by HGNC Official Full Name ficolin 1provided by HGNC Primary source HGNC:HGNC:3623 See related Ensembl:ENSG00000085265 MIM:601252; AllianceGenome:HGNC:3623 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FCNM Summary The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 318.5), appendix (RPKM 117.5) and 3 other tissues See more Orthologs mouse all