AASDHPPT, Official Symbol AASDHPPTprovided by HGNC Official Full Name aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferaseprovided by HGNC Primary source HGNC:HGNC:14235 See related Ensembl:ENSG00000149313 MIM:607756; AllianceGenome:HGNC:14235 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACPS; LYS2; LYS5; CGI-80; AASD-PPT Summary The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 32.8), testis (RPKM 17.4) and 25 other tissues See more Orthologs mouse all