CARF, Official Symbol CARFprovided by HGNC Official Full Name calcium responsive transcription factorprovided by HGNC Primary source HGNC:HGNC:14435 See related Ensembl:ENSG00000138380 MIM:607586; AllianceGenome:HGNC:14435 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALS2CR8; NYD-SP24 Summary Enables DNA binding activity and DNA-binding transcription factor activity. Involved in cellular response to potassium ion and positive regulation of transcription from RNA polymerase II promoter in response to calcium ion. Predicted to be located in granular component. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 5.9), thyroid (RPKM 3.4) and 24 other tissues See more Orthologs mouse all