POLR2C, Official Symbol POLR2Cprovided by HGNC Official Full Name RNA polymerase II subunit Cprovided by HGNC Primary source HGNC:HGNC:9189 See related Ensembl:ENSG00000102978 MIM:180663; AllianceGenome:HGNC:9189 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RPB3; RPB31; hRPB33; hsRPB3 Summary This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 43.5), adrenal (RPKM 39.1) and 25 other tissues See more Orthologs mouse all