OGA, Official Symbol OGAprovided by HGNC Official Full Name O-GlcNAcaseprovided by HGNC Primary source HGNC:HGNC:7056 See related Ensembl:ENSG00000198408 MIM:604039; AllianceGenome:HGNC:7056 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MEA5; MGEA5; NCOAT Summary The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in brain (RPKM 42.8), lymph node (RPKM 37.2) and 25 other tissues See more Orthologs mouse all