ZNF281, Official Symbol ZNF281provided by HGNC Official Full Name zinc finger protein 281provided by HGNC Primary source HGNC:HGNC:13075 See related Ensembl:ENSG00000162702 MIM:618703; AllianceGenome:HGNC:13075 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GZP1; ZBP99; ZBP-99; ZNP-99 Summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of gene expression; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription, DNA-templated. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 10.1), appendix (RPKM 5.7) and 25 other tissues See more Orthologs mouse all