NT5C, Official Symbol NT5Cprovided by HGNC Official Full Name 5', 3'-nucleotidase, cytosolicprovided by HGNC Primary source HGNC:HGNC:17144 See related Ensembl:ENSG00000125458 MIM:191720; AllianceGenome:HGNC:17144 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DNT; cdN; DNT1; P5N2; PN-I; HEL74; PN-II; UMPH2; dNT-1 Summary This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] Expression Ubiquitous expression in colon (RPKM 12.8), spleen (RPKM 11.1) and 25 other tissues See more Orthologs mouse all