CNGB3, Official Symbol CNGB3provided by HGNC Official Full Name cyclic nucleotide gated channel subunit beta 3provided by HGNC Primary source HGNC:HGNC:2153 See related Ensembl:ENSG00000170289 MIM:605080; AllianceGenome:HGNC:2153 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACHM1 Summary This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease. [provided by RefSeq, Feb 2010] Expression Biased expression in testis (RPKM 1.1), endometrium (RPKM 0.1) and 1 other tissue See more Orthologs mouse all