ST3GAL1, Official Symbol ST3GAL1provided by HGNC Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 1provided by HGNC Primary source HGNC:HGNC:10862 See related Ensembl:ENSG00000008513 MIM:607187; AllianceGenome:HGNC:10862 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ST3O; SIAT4A; SIATFL; ST3GalA; ST3GalIA; Gal-NAc6S; ST3GalA.1; ST3GalIA,1 Summary The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008] Expression Broad expression in thyroid (RPKM 30.7), kidney (RPKM 13.0) and 22 other tissues See more Orthologs mouse all