EZH1, Official Symbol EZH1provided by HGNC Official Full Name enhancer of zeste 1 polycomb repressive complex 2 subunitprovided by HGNC Primary source HGNC:HGNC:3526 See related Ensembl:ENSG00000108799 MIM:601674; AllianceGenome:HGNC:3526 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KMT6B Summary EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009] Expression Ubiquitous expression in ovary (RPKM 23.1), fat (RPKM 20.0) and 25 other tissues See more Orthologs mouse all