STK25, Official Symbol STK25provided by HGNC Official Full Name serine/threonine kinase 25provided by HGNC Primary source HGNC:HGNC:11404 See related Ensembl:ENSG00000115694 MIM:602255; AllianceGenome:HGNC:11404 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SOK1; YSK1 Summary This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012] Expression Ubiquitous expression in brain (RPKM 17.8), thyroid (RPKM 17.1) and 25 other tissues See more Orthologs mouse all