GCSAM, Official Symbol GCSAMprovided by HGNC Official Full Name germinal center associated signaling and motilityprovided by HGNC Primary source HGNC:HGNC:20253 See related Ensembl:ENSG00000174500 MIM:607792; AllianceGenome:HGNC:20253 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HGAL; GCAT2; GCET2 Summary This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Biased expression in lymph node (RPKM 14.9), skin (RPKM 5.8) and 13 other tissues See more Orthologs mouse all