AMN, Official Symbol AMNprovided by HGNC Official Full Name amnion associated transmembrane proteinprovided by HGNC Primary source HGNC:HGNC:14604 See related Ensembl:ENSG00000166126 MIM:605799; AllianceGenome:HGNC:14604 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IGS2; PRO1028; amnionless Summary The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 39.0), small intestine (RPKM 30.0) and 4 other tissues See more Orthologs mouse all