PROP1, Official Symbol PROP1provided by HGNC Official Full Name PROP paired-like homeobox 1provided by HGNC Primary source HGNC:HGNC:9455 See related Ensembl:ENSG00000175325 MIM:601538; AllianceGenome:HGNC:9455 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPHD2; PROP-1 Summary This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011] Expression Low expression observed in reference dataset See more Orthologs mouse all