SLC22A12, Official Symbol SLC22A12provided by HGNC Official Full Name solute carrier family 22 member 12provided by HGNC Primary source HGNC:HGNC:17989 See related Ensembl:ENSG00000197891 MIM:607096; AllianceGenome:HGNC:17989 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RST; UAT; OAT4L; URAT1; hURAT1 Summary The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Expression Restricted expression toward kidney (RPKM 60.9) See more Orthologs all