SCG5, Official Symbol SCG5provided by HGNC Official Full Name secretogranin Vprovided by HGNC Primary source HGNC:HGNC:10816 See related Ensembl:ENSG00000166922 MIM:173120; AllianceGenome:HGNC:10816 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 7B2; SgV; P7B2; SGNE1 Summary This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019] Expression Biased expression in brain (RPKM 106.2), adrenal (RPKM 48.4) and 4 other tissues See more Orthologs mouse all