RCAN2, Official Symbol RCAN2provided by HGNC Official Full Name regulator of calcineurin 2provided by HGNC Primary source HGNC:HGNC:3041 See related Ensembl:ENSG00000172348 MIM:604876; AllianceGenome:HGNC:3041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CSP2; RCN2; MCIP2; ZAKI4; ZAKI-4; DSCR1L1 Summary This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] Expression Broad expression in heart (RPKM 64.4), brain (RPKM 36.0) and 18 other tissues See more Orthologs mouse all