USP11, Official Symbol USP11provided by HGNC Official Full Name ubiquitin specific peptidase 11provided by HGNC Primary source HGNC:HGNC:12609 See related Ensembl:ENSG00000102226 MIM:300050; AllianceGenome:HGNC:12609 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UHX1 Summary Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 81.8), ovary (RPKM 32.3) and 22 other tissues See more Orthologs mouse all