KRT7, Official Symbol KRT7provided by HGNC Official Full Name keratin 7provided by HGNC Primary source HGNC:HGNC:6445 See related Ensembl:ENSG00000135480 MIM:148059; AllianceGenome:HGNC:6445 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K7; CK7; SCL; K2C7 Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] Expression Biased expression in thyroid (RPKM 146.2), placenta (RPKM 75.4) and 5 other tissues See more Orthologs mouse all