ACER3, Official Symbol ACER3provided by HGNC Official Full Name alkaline ceramidase 3provided by HGNC Primary source HGNC:HGNC:16066 See related Ensembl:ENSG00000078124 MIM:617036; AllianceGenome:HGNC:16066 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APHC; PHCA; PLDECO Summary Enables N-acylsphingosine amidohydrolase activity and metal ion binding activity. Involved in several processes, including myelination; positive regulation of cell population proliferation; and sphingolipid metabolic process. Is integral component of Golgi membrane and integral component of endoplasmic reticulum membrane. Biomarker of hepatocellular carcinoma and non-alcoholic steatohepatitis. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 8.3), brain (RPKM 5.5) and 24 other tissues See more Orthologs mouse all