PREPL, Official Symbol PREPLprovided by HGNC Official Full Name prolyl endopeptidase likeprovided by HGNC Primary source HGNC:HGNC:30228 See related Ensembl:ENSG00000138078 MIM:609557; AllianceGenome:HGNC:30228 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CMS22 Summary The protein encoded by this gene belongs to the prolyl oligopeptidase subfamily of serine peptidases. Mutations in this gene have been associated with hypotonia-cystinuria syndrome, also known as the 2p21 deletion syndrome. Several alternatively spliced transcript variants encoding either the same or different isoforms have been described for this gene.[provided by RefSeq, Jan 2010] Expression Broad expression in brain (RPKM 66.6), kidney (RPKM 33.1) and 24 other tissues See more Orthologs mouse all