PTGER3, Official Symbol PTGER3provided by HGNC Official Full Name prostaglandin E receptor 3provided by HGNC Primary source HGNC:HGNC:9595 See related Ensembl:ENSG00000050628 MIM:176806; AllianceGenome:HGNC:9595 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EP3; EP3e; EP3-I; EP3-II; EP3-IV; EP3-VI; PGE2-R; EP3-III; lnc003875 Summary The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] Expression Biased expression in endometrium (RPKM 21.7), kidney (RPKM 19.2) and 8 other tissues See more Orthologs mouse all