WIPF1, Official Symbol WIPF1provided by HGNC Official Full Name WAS/WASL interacting protein family member 1provided by HGNC Primary source HGNC:HGNC:12736 See related Ensembl:ENSG00000115935 MIM:602357; AllianceGenome:HGNC:12736 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WIP; WAS2; PRPL-2; WASPIP Summary This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in lymph node (RPKM 61.9), appendix (RPKM 50.1) and 23 other tissues See more Orthologs mouse all