ERAS, Official Symbol ERASprovided by HGNC Official Full Name ES cell expressed Rasprovided by HGNC Primary source HGNC:HGNC:5174 See related Ensembl:ENSG00000187682 MIM:300437; AllianceGenome:HGNC:5174 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HRAS2; HRASP Summary This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012] Expression Low expression observed in reference dataset See more Orthologs mouse all