MRPS14, Official Symbol MRPS14provided by HGNC Official Full Name mitochondrial ribosomal protein S14provided by HGNC Primary source HGNC:HGNC:14049 See related Ensembl:ENSG00000120333 MIM:611978; AllianceGenome:HGNC:14049 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as S14mt; uS14m; COXPD38; MRP-S14; HSMRPS14; DJ262D12.2 Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010] Expression Ubiquitous expression in brain (RPKM 14.6), thyroid (RPKM 14.5) and 25 other tissues See more Orthologs mouse all