EXOSC4, Official Symbol EXOSC4provided by HGNC Official Full Name exosome component 4provided by HGNC Primary source HGNC:HGNC:18189 See related Ensembl:ENSG00000178896 MIM:606491; AllianceGenome:HGNC:18189 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SKI6; p12A; RRP41; Ski6p; RRP41A; Rrp41p; hRrp41p Summary Enables mRNA 3'-UTR AU-rich region binding activity. Involved in nucleic acid metabolic process and positive regulation of cell growth. Acts upstream of or within defense response to virus. Located in cytosol; nucleoplasm; and transcriptionally active chromatin. Part of exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 19.8), kidney (RPKM 7.7) and 25 other tissues See more Orthologs mouse all