MCM5, Official Symbol MCM5provided by HGNC Official Full Name minichromosome maintenance complex component 5provided by HGNC Primary source HGNC:HGNC:6948 See related Ensembl:ENSG00000100297 MIM:602696; AllianceGenome:HGNC:6948 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDC46; MGORS8; P1-CDC46 Summary The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008] Expression Broad expression in bone marrow (RPKM 35.9), lymph node (RPKM 27.6) and 24 other tissues See more Orthologs mouse all