LAPTM4B, Official Symbol LAPTM4Bprovided by HGNC Official Full Name lysosomal protein transmembrane 4 betaprovided by HGNC Primary source HGNC:HGNC:13646 See related Ensembl:ENSG00000104341 MIM:613296; AllianceGenome:HGNC:13646 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LC27; LAPTM4beta Summary Enables ceramide binding activity; enzyme binding activity; and phosphatidylinositol bisphosphate binding activity. Involved in several processes, including negative regulation of macromolecule metabolic process; regulation of lysosomal membrane permeability; and regulation of lysosome organization. Located in several cellular components, including endosome; lysosomal membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in heart (RPKM 97.2), testis (RPKM 52.3) and 23 other tissues See more Orthologs mouse all