RXRG, Official Symbol RXRGprovided by HGNC Official Full Name retinoid X receptor gammaprovided by HGNC Primary source HGNC:HGNC:10479 See related Ensembl:ENSG00000143171 MIM:180247; AllianceGenome:HGNC:10479 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RXRC; NR2B3; RXRgamma; RXR-gamma Summary This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010] Expression Broad expression in heart (RPKM 1.5), adrenal (RPKM 1.5) and 22 other tissues See more Orthologs mouse all