AKAP6, Official Symbol AKAP6provided by HGNC Official Full Name A-kinase anchoring protein 6provided by HGNC Primary source HGNC:HGNC:376 See related Ensembl:ENSG00000151320 MIM:604691; AllianceGenome:HGNC:376 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADAP6; PRKA6; mAKAP; ADAP100; AKAP100 Summary The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 9.8), heart (RPKM 7.6) and 12 other tissues See more Orthologs mouse all