CNOT6, Official Symbol CNOT6provided by HGNC Official Full Name CCR4-NOT transcription complex subunit 6provided by HGNC Primary source HGNC:HGNC:14099 See related Ensembl:ENSG00000113300 MIM:608951; AllianceGenome:HGNC:14099 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCR4; Ccr4a Summary This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in testis (RPKM 8.0), urinary bladder (RPKM 6.4) and 25 other tissues See more Orthologs mouse all