WDR54, Official Symbol WDR54provided by HGNC Official Full Name WD repeat domain 54provided by HGNC Primary source HGNC:HGNC:25770 See related Ensembl:ENSG00000005448 AllianceGenome:HGNC:25770 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables protein homodimerization activity. Involved in negative regulation of receptor internalization; regulation of MAPK cascade; and regulation of epidermal growth factor receptor signaling pathway. Located in vesicle. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 18.8), lung (RPKM 6.6) and 23 other tissues See more Orthologs mouse all