NTS, Official Symbol NTSprovided by HGNC Official Full Name neurotensinprovided by HGNC Primary source HGNC:HGNC:8038 See related Ensembl:ENSG00000133636 MIM:162650; AllianceGenome:HGNC:8038 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NN; NT; NT/N; NTS1; NMN-125 Summary This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014] Expression Biased expression in small intestine (RPKM 86.5), stomach (RPKM 27.6) and 1 other tissue See more Orthologs mouse all