LYRM4, Official Symbol LYRM4provided by HGNC Official Full Name LYR motif containing 4provided by HGNC Primary source HGNC:HGNC:21365 See related Ensembl:ENSG00000214113 MIM:613311; AllianceGenome:HGNC:21365 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ISD11; CGI-203; COXPD19; C6orf149 Summary The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis. [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in ovary (RPKM 2.3), thyroid (RPKM 2.1) and 25 other tissues See more Orthologs mouse all