TAS2R46, Official Symbol TAS2R46provided by HGNC Official Full Name taste 2 receptor member 46provided by HGNC Primary source HGNC:HGNC:18877 See related Ensembl:ENSG00000226761 MIM:612774; AllianceGenome:HGNC:18877 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as T2R46; T2R54 Summary TAS2R46 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Sep 2009]