SLC8A3, Official Symbol SLC8A3provided by HGNC Official Full Name solute carrier family 8 member A3provided by HGNC Primary source HGNC:HGNC:11070 See related Ensembl:ENSG00000100678 MIM:607991; AllianceGenome:HGNC:11070 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCX3 Summary This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013] Expression Biased expression in brain (RPKM 2.0), adrenal (RPKM 0.3) and 4 other tissues See more Orthologs mouse all