TPPP, Official Symbol TPPPprovided by HGNC Official Full Name tubulin polymerization promoting proteinprovided by HGNC Primary source HGNC:HGNC:24164 See related Ensembl:ENSG00000171368 MIM:608773; AllianceGenome:HGNC:24164 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p24; p25; TPPP1; TPPP/p25; p25alpha Summary Enables several functions, including GTPase activity; magnesium ion binding activity; and protein homodimerization activity. Involved in several processes, including microtubule cytoskeleton organization; negative regulation of tubulin deacetylation; and positive regulation of protein polymerization. Located in several cellular components, including mitochondrion; mitotic spindle; and perinuclear region of cytoplasm. Colocalizes with microtubule and microtubule bundle. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 45.7), lung (RPKM 7.7) and 9 other tissues See more Orthologs mouse all