TP53INP2, Official Symbol TP53INP2provided by HGNC Official Full Name tumor protein p53 inducible nuclear protein 2provided by HGNC Primary source HGNC:HGNC:16104 See related Ensembl:ENSG00000078804 MIM:617549; AllianceGenome:HGNC:16104 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DOR; PIGU; PINH; PIG-U; C20orf110; dJ1181N3.1 Summary The protein encoded by this gene promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in esophagus (RPKM 35.1), brain (RPKM 34.7) and 25 other tissues See more Orthologs mouse all