KBTBD6, Official Symbol KBTBD6provided by HGNC Official Full Name kelch repeat and BTB domain containing 6provided by HGNC Primary source HGNC:HGNC:25340 See related Ensembl:ENSG00000165572 MIM:617738; AllianceGenome:HGNC:25340 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; and regulation of Rac protein signal transduction. Located in cytoplasm and nucleus. Part of Cul3-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Orthologs all