B4GALNT1, Official Symbol B4GALNT1provided by HGNC Official Full Name beta-1,4-N-acetyl-galactosaminyltransferase 1provided by HGNC Primary source HGNC:HGNC:4117 See related Ensembl:ENSG00000135454 MIM:601873; AllianceGenome:HGNC:4117 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GALGT; SPG26; GALNACT; GalNAc-T Summary GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] Expression Broad expression in brain (RPKM 8.2), endometrium (RPKM 1.8) and 16 other tissues See more Orthologs mouse all