PLPBP, Official Symbol PLPBPprovided by HGNC Official Full Name pyridoxal phosphate binding proteinprovided by HGNC Primary source HGNC:HGNC:9457 See related Ensembl:ENSG00000147471 MIM:604436; AllianceGenome:HGNC:9457 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPEO1; PROSC; EPVB6D Summary This gene encodes a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 2017] Expression Ubiquitous expression in kidney (RPKM 12.8), colon (RPKM 10.6) and 25 other tissues See more Orthologs mouse all