MLXIPL, Official Symbol MLXIPLprovided by HGNC Official Full Name MLX interacting protein likeprovided by HGNC Primary source HGNC:HGNC:12744 See related Ensembl:ENSG00000009950 MIM:605678; AllianceGenome:HGNC:12744 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIO; MLX; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14 Summary This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Biased expression in fat (RPKM 35.0), liver (RPKM 27.7) and 8 other tissues See more Orthologs mouse all