PIWIL1, Official Symbol PIWIL1provided by HGNC Official Full Name piwi like RNA-mediated gene silencing 1provided by HGNC Primary source HGNC:HGNC:9007 See related Ensembl:ENSG00000125207 MIM:605571; AllianceGenome:HGNC:9007 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HIWI; MIWI; PIWI; CT80.1 Summary This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] Expression Restricted expression toward testis (RPKM 57.0) See more Orthologs mouse all