CCRL2, Official Symbol CCRL2provided by HGNC Official Full Name C-C motif chemokine receptor like 2provided by HGNC Primary source HGNC:HGNC:1612 See related Ensembl:ENSG00000121797 MIM:608379; AllianceGenome:HGNC:1612 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HCR; CKRX; CRAM; ACKR5; CRAM-A; CRAM-B Summary This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008] Expression Broad expression in appendix (RPKM 6.4), lung (RPKM 6.3) and 20 other tissues See more Orthologs mouse all