DOK2, Official Symbol DOK2provided by HGNC Official Full Name docking protein 2provided by HGNC Primary source HGNC:HGNC:2991 See related Ensembl:ENSG00000147443 MIM:604997; AllianceGenome:HGNC:2991 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p56DOK; p56dok-2 Summary The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008] Expression Broad expression in spleen (RPKM 18.2), lung (RPKM 14.7) and 18 other tissues See more Orthologs mouse all