ADD1, Official Symbol ADD1provided by HGNC Official Full Name adducin 1provided by HGNC Primary source HGNC:HGNC:243 See related Ensembl:ENSG00000087274 MIM:102680; AllianceGenome:HGNC:243 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADDA Summary Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017] Expression Ubiquitous expression in brain (RPKM 57.3), ovary (RPKM 51.1) and 25 other tissues See more Orthologs mouse all