FOS, Official Symbol FOSprovided by HGNC Official Full Name Fos proto-oncogene, AP-1 transcription factor subunitprovided by HGNC Primary source HGNC:HGNC:3796 See related Ensembl:ENSG00000170345 MIM:164810; AllianceGenome:HGNC:3796 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p55; AP-1; C-FOS Summary The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008] Expression Broad expression in bone marrow (RPKM 802.2), gall bladder (RPKM 632.2) and 23 other tissues See more Orthologs mouse all