RASSF6, Official Symbol RASSF6provided by HGNC Official Full Name Ras association domain family member 6provided by HGNC Primary source HGNC:HGNC:20796 See related Ensembl:ENSG00000169435 MIM:612620; AllianceGenome:HGNC:20796 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] Expression Broad expression in stomach (RPKM 5.6), colon (RPKM 3.3) and 15 other tissues See more Orthologs mouse all