LGR4, Official Symbol LGR4provided by HGNC Official Full Name leucine rich repeat containing G protein-coupled receptor 4provided by HGNC Primary source HGNC:HGNC:13299 See related Ensembl:ENSG00000205213 MIM:606666; AllianceGenome:HGNC:13299 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DPSL; GPR48; BNMD17 Summary The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in kidney (RPKM 28.0), colon (RPKM 27.7) and 23 other tissues See more Orthologs mouse all