TXN, Official Symbol TXNprovided by HGNC Official Full Name thioredoxinprovided by HGNC Primary source HGNC:HGNC:12435 See related Ensembl:ENSG00000136810 MIM:187700; AllianceGenome:HGNC:12435 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRX; TRDX; TRX1; TXN1; Trx80 Summary The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Expression Ubiquitous expression in esophagus (RPKM 218.4), colon (RPKM 150.6) and 24 other tissues See more Orthologs mouse all