CELA2A, Official Symbol CELA2Aprovided by HGNC Official Full Name chymotrypsin like elastase 2Aprovided by HGNC Primary source HGNC:HGNC:24609 See related Ensembl:ENSG00000142615 MIM:609443; AllianceGenome:HGNC:24609 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PE-1; AOMS4; ELA2A Summary Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, May 2009] Expression Restricted expression toward pancreas (RPKM 18580.0) See more Orthologs mouse all