PAUPAR, Official Symbol PAUPARprovided by HGNC Official Full Name PAX6 upstream antisense RNAprovided by HGNC Primary source HGNC:HGNC:49670 See related Ensembl:ENSG00000281880 AllianceGenome:HGNC:49670 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is thought to produce a functional long non-coding RNA. Knockdown of this transcript results in genome-wide changes in gene expression, particularly of cell cyle genes, indicating a role in regulating differentiation. This transcript may bind to the promoter region of target genes and may also interact with the transcription factor Pax6 (paired box 6). [provided by RefSeq, Feb 2015] Orthologs mouse all