ADHFE1, Official Symbol ADHFE1provided by HGNC Official Full Name alcohol dehydrogenase iron containing 1provided by HGNC Primary source HGNC:HGNC:16354 See related Ensembl:ENSG00000147576 MIM:611083; AllianceGenome:HGNC:16354 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOT; ADH8; HMFT2263 Summary The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 1.1.99.24), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in heart (RPKM 16.3), fat (RPKM 15.2) and 25 other tissues See more Orthologs mouse all