NUDCD3, Official Symbol NUDCD3provided by HGNC Official Full Name NudC domain containing 3provided by HGNC Primary source HGNC:HGNC:22208 See related Ensembl:ENSG00000015676 MIM:610296; AllianceGenome:HGNC:22208 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NudCL Summary The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 28.0), ovary (RPKM 14.4) and 25 other tissues See more Orthologs mouse all