KCNE4, Official Symbol KCNE4provided by HGNC Official Full Name potassium voltage-gated channel subfamily E regulatory subunit 4provided by HGNC Primary source HGNC:HGNC:6244 See related Ensembl:ENSG00000152049 MIM:607775; AllianceGenome:HGNC:6244 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIRP3 Summary Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus. [provided by RefSeq, Jul 2008] Expression Broad expression in endometrium (RPKM 17.0), gall bladder (RPKM 15.1) and 21 other tissues See more Orthologs mouse all