CDC42BPB, Official Symbol CDC42BPBprovided by HGNC Official Full Name CDC42 binding protein kinase betaprovided by HGNC Primary source HGNC:HGNC:1738 See related Ensembl:ENSG00000198752 MIM:614062; AllianceGenome:HGNC:1738 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRCKB; CHOCNS Summary This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 24.8), fat (RPKM 20.9) and 24 other tissues See more Orthologs mouse all