RAB3GAP2, Official Symbol RAB3GAP2provided by HGNC Official Full Name RAB3 GTPase activating non-catalytic protein subunit 2provided by HGNC Primary source HGNC:HGNC:17168 See related Ensembl:ENSG00000118873 MIM:609275; AllianceGenome:HGNC:17168 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p150; SPG69; MARTS1; WARBM2; RAB3GAP150; RAB3-GAP150 Summary The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009] Expression Ubiquitous expression in thyroid (RPKM 9.2), brain (RPKM 7.7) and 25 other tissues See more Orthologs mouse all