VTCN1, Official Symbol VTCN1provided by HGNC Official Full Name V-set domain containing T cell activation inhibitor 1provided by HGNC Primary source HGNC:HGNC:28873 See related Ensembl:ENSG00000134258 MIM:608162; AllianceGenome:HGNC:28873 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291 Summary This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Biased expression in kidney (RPKM 5.0), pancreas (RPKM 2.8) and 9 other tissues See more Orthologs mouse all