GJA8, Official Symbol GJA8provided by HGNC Official Full Name gap junction protein alpha 8provided by HGNC Primary source HGNC:HGNC:4281 See related Ensembl:ENSG00000121634 MIM:600897; AllianceGenome:HGNC:4281 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAE; CAE1; CX50; CZP1; MP70; CTRCT1 Summary This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009] Expression Restricted expression toward testis (RPKM 2.4) See more Orthologs mouse all