FCAR, Official Symbol FCARprovided by HGNC Official Full Name Fc alpha receptorprovided by HGNC Primary source HGNC:HGNC:3608 See related Ensembl:ENSG00000186431 MIM:147045; AllianceGenome:HGNC:3608 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD89; FcalphaR; FcalphaRI; CTB-61M7.2 Summary This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Expression Restricted expression toward bone marrow (RPKM 95.4) See more Orthologs all