FADS2, Official Symbol FADS2provided by HGNC Official Full Name fatty acid desaturase 2provided by HGNC Primary source HGNC:HGNC:3575 See related Ensembl:ENSG00000134824 MIM:606149; AllianceGenome:HGNC:3575 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as D6D; DES6; TU13; FADSD6; LLCDL2; SLL0262 Summary The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] Expression Broad expression in adrenal (RPKM 104.8), brain (RPKM 64.0) and 16 other tissues See more Orthologs mouse all