HEBP2, Official Symbol HEBP2provided by HGNC Official Full Name heme binding protein 2provided by HGNC Primary source HGNC:HGNC:15716 See related Ensembl:ENSG00000051620 MIM:605825; AllianceGenome:HGNC:15716 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP23; SOUL; C6orf34; C6ORF34B Summary The protein encoded by this gene is found predominately in the cytoplasm, where it plays a role in the collapse of mitochondrial membrane potential (MMP) prior to necrotic cell death. The encoded protein enhances outer and inner mitochondrial membrane permeabilization, especially under conditions of oxidative stress. [provided by RefSeq, May 2016] Expression Ubiquitous expression in fat (RPKM 80.4), prostate (RPKM 27.2) and 22 other tissues See more Orthologs mouse all