CRABP2, Official Symbol CRABP2provided by HGNC Official Full Name cellular retinoic acid binding protein 2provided by HGNC Primary source HGNC:HGNC:2339 See related Ensembl:ENSG00000143320 MIM:180231; AllianceGenome:HGNC:2339 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RBP6; CRABP-II Summary This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010] Expression Biased expression in esophagus (RPKM 46.7), skin (RPKM 7.1) and 2 other tissues See more Orthologs mouse all