LILRA5, Official Symbol LILRA5provided by HGNC Official Full Name leukocyte immunoglobulin like receptor A5provided by HGNC Primary source HGNC:HGNC:16309 See related Ensembl:ENSG00000187116 MIM:606047; AllianceGenome:HGNC:16309 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD85; LIR9; CD85F; ILT11; LIR-9; ILT-11; LILRB7 Summary The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in appendix (RPKM 29.5), bone marrow (RPKM 22.9) and 4 other tissues See more Orthologs all