GSPT2, Official Symbol GSPT2provided by HGNC Official Full Name G1 to S phase transition 2provided by HGNC Primary source HGNC:HGNC:4622 See related Ensembl:ENSG00000189369 MIM:300418; AllianceGenome:HGNC:4622 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GST2; ERF3B Summary This gene encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.[provided by RefSeq, Mar 2010] Orthologs all