CENPU, Official Symbol CENPUprovided by HGNC Official Full Name centromere protein Uprovided by HGNC Primary source HGNC:HGNC:21348 See related Ensembl:ENSG00000151725 MIM:611511; AllianceGenome:HGNC:21348 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KLIP1; PBIP1; CENP50; MLF1IP; CENPU50 Summary The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008] Expression Biased expression in testis (RPKM 44.2), bone marrow (RPKM 27.7) and 10 other tissues See more Orthologs mouse all