TMED4, Official Symbol TMED4provided by HGNC Official Full Name transmembrane p24 trafficking protein 4provided by HGNC Primary source HGNC:HGNC:22301 See related Ensembl:ENSG00000158604 MIM:612038; AllianceGenome:HGNC:22301 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNLF; ERS25; p24a3; GMP25iso; p24alpha3 Summary Involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 37.8), small intestine (RPKM 27.8) and 25 other tissues See more Orthologs mouse all