MED24, Official Symbol MED24provided by HGNC Official Full Name mediator complex subunit 24provided by HGNC Primary source HGNC:HGNC:22963 See related Ensembl:ENSG00000008838 MIM:607000; AllianceGenome:HGNC:22963 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MED5; CRSP4; ARC100; THRAP4; CRSP100; DRIP100; TRAP100 Summary This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 18.9), brain (RPKM 13.4) and 25 other tissues See more Orthologs mouse all