PPP6R1, Official Symbol PPP6R1provided by HGNC Official Full Name protein phosphatase 6 regulatory subunit 1provided by HGNC Primary source HGNC:HGNC:29195 See related Ensembl:ENSG00000105063 MIM:610875; AllianceGenome:HGNC:29195 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP6R1; SAPS1; SAP190; KIAA1115 Summary Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010] Expression Broad expression in testis (RPKM 56.4), lymph node (RPKM 37.5) and 24 other tissues See more Orthologs mouse all