TICAM2, Official Symbol TICAM2provided by HGNC Official Full Name TIR domain containing adaptor molecule 2provided by HGNC Primary source HGNC:HGNC:21354 See related Ensembl:ENSG00000243414 MIM:608321; AllianceGenome:HGNC:21354 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIRP; TRAM; TIRAP3; MyD88-4; TICAM-2 Summary Predicted to enable phospholipid binding activity. Involved in several processes, including TRAM-dependent toll-like receptor 4 signaling pathway; regulation of chemokine (C-C motif) ligand 5 production; and regulation of toll-like receptor 4 signaling pathway. Located in endoplasmic reticulum; endosome; and phagocytic cup. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in appendix (RPKM 4.0), spleen (RPKM 3.2) and 25 other tissues See more Orthologs mouse all