LGALS3BP, Official Symbol LGALS3BPprovided by HGNC Official Full Name galectin 3 binding proteinprovided by HGNC Primary source HGNC:HGNC:6564 See related Ensembl:ENSG00000108679 MIM:600626; AllianceGenome:HGNC:6564 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B Summary The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in stomach (RPKM 179.8), colon (RPKM 156.8) and 25 other tissues See more Orthologs mouse all