PEDS1-UBE2V1, Official Symbol PEDS1-UBE2V1provided by HGNC Official Full Name PEDS1-UBE2V1 readthroughprovided by HGNC Primary source HGNC:HGNC:33521 See related Ensembl:ENSG00000124208 AllianceGenome:HGNC:33521 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CROC1B; CROC-1B; KUA-UEV; TMEM189-UBE2V1 Summary The TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined. [provided by RefSeq, Oct 2010] Expression Ubiquitous expression in brain (RPKM 35.8), placenta (RPKM 35.8) and 25 other tissues See more Orthologs all