CADPS, Official Symbol CADPSprovided by HGNC Official Full Name calcium dependent secretion activatorprovided by HGNC Primary source HGNC:HGNC:1426 See related Ensembl:ENSG00000163618 MIM:604667; AllianceGenome:HGNC:1426 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAPS; CAPS1; CADPS1; UNC-31 Summary This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008] Expression Biased expression in brain (RPKM 14.7), adrenal (RPKM 5.4) and 9 other tissues See more Orthologs mouse all