SOCS5, Official Symbol SOCS5provided by HGNC Official Full Name suppressor of cytokine signaling 5provided by HGNC Primary source HGNC:HGNC:16852 See related Ensembl:ENSG00000171150 MIM:607094; AllianceGenome:HGNC:16852 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CIS6; CISH6; Cish5; SOCS-5 Summary The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 13.6), endometrium (RPKM 9.7) and 25 other tissues See more Orthologs mouse all