DCAF1, Official Symbol DCAF1provided by HGNC Official Full Name DDB1 and CUL4 associated factor 1provided by HGNC Primary source HGNC:HGNC:30911 See related Ensembl:ENSG00000145041 MIM:617259; AllianceGenome:HGNC:30911 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIP; VPRBP Summary Enables estrogen receptor binding activity and histone kinase activity (H2A-T120 specific). Involved in cell competition in a multicellular organism; histone H2A-T120 phosphorylation; and negative regulation of transcription by RNA polymerase II. Located in fibrillar center and nucleoplasm. Part of Cul4-RING E3 ubiquitin ligase complex. Colocalizes with COP9 signalosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 27.5), thyroid (RPKM 8.3) and 24 other tissues See more Orthologs mouse all