NUP62, Official Symbol NUP62provided by HGNC Official Full Name nucleoporin 62provided by HGNC Primary source HGNC:HGNC:8066 See related Ensembl:ENSG00000213024 MIM:605815; AllianceGenome:HGNC:8066 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p62; IBSN; SNDI Summary The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 21.4), appendix (RPKM 16.1) and 25 other tissues See more Orthologs mouse all