PATJ, Official Symbol PATJprovided by HGNC Official Full Name PATJ crumbs cell polarity complex componentprovided by HGNC Primary source HGNC:HGNC:28881 See related Ensembl:ENSG00000132849 MIM:603199; AllianceGenome:HGNC:28881 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Cipp; INADL; hINADL; InaD-like Summary This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 14.4), heart (RPKM 7.9) and 24 other tissues See more Orthologs mouse all