GADD45G, Official Symbol GADD45Gprovided by HGNC Official Full Name growth arrest and DNA damage inducible gammaprovided by HGNC Primary source HGNC:HGNC:4097 See related Ensembl:ENSG00000130222 MIM:604949; AllianceGenome:HGNC:4097 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CR6; DDIT2; GRP17; GADD45gamma Summary This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008] Expression Broad expression in liver (RPKM 21.4), placenta (RPKM 16.8) and 22 other tissues See more Orthologs mouse all