ACTR3, Official Symbol ACTR3provided by HGNC Official Full Name actin related protein 3provided by HGNC Primary source HGNC:HGNC:170 See related Ensembl:ENSG00000115091 MIM:604222; AllianceGenome:HGNC:170 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARP3 Summary The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013] Expression Ubiquitous expression in lymph node (RPKM 65.6), appendix (RPKM 59.7) and 24 other tissues See more Orthologs mouse all