MED13L, Official Symbol MED13Lprovided by HGNC Official Full Name mediator complex subunit 13Lprovided by HGNC Primary source HGNC:HGNC:22962 See related Ensembl:ENSG00000123066 MIM:608771; AllianceGenome:HGNC:22962 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRFACD; THRAP2; TRAP240L; PROSIT240 Summary The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010] Expression Ubiquitous expression in bone marrow (RPKM 23.0), ovary (RPKM 14.7) and 25 other tissues See more Orthologs mouse all