FST, Official Symbol FSTprovided by HGNC Official Full Name follistatinprovided by HGNC Primary source HGNC:HGNC:3971 See related Ensembl:ENSG00000134363 MIM:136470; AllianceGenome:HGNC:3971 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FS Summary Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008] Expression Broad expression in liver (RPKM 13.6), placenta (RPKM 7.9) and 16 other tissues See more Orthologs mouse all