LAMTOR1, Official Symbol LAMTOR1provided by HGNC Official Full Name late endosomal/lysosomal adaptor, MAPK and MTOR activator 1provided by HGNC Primary source HGNC:HGNC:26068 See related Ensembl:ENSG00000149357 MIM:613510; AllianceGenome:HGNC:26068 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p18; PDRO; C11orf59; p27RF-Rho; Ragulator1 Summary Enables GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TOR signaling; and regulation of cholesterol transport. Located in lysosome. Part of Ragulator complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 58.6), adrenal (RPKM 40.5) and 25 other tissues See more Orthologs mouse all