PTP4A1, Official Symbol PTP4A1provided by HGNC Official Full Name protein tyrosine phosphatase 4A1provided by HGNC Primary source HGNC:HGNC:9634 See related Ensembl:ENSG00000112245 MIM:601585; AllianceGenome:HGNC:9634 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1) Summary This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013] Expression Broad expression in liver (RPKM 141.5), adrenal (RPKM 72.5) and 24 other tissues See more Orthologs mouse all