ECHS1, Official Symbol ECHS1provided by HGNC Official Full Name enoyl-CoA hydratase, short chain 1provided by HGNC Primary source HGNC:HGNC:3151 See related Ensembl:ENSG00000127884 MIM:602292; AllianceGenome:HGNC:3151 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCEH; mECH; mECH1; ECHS1D Summary The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008] Expression Broad expression in liver (RPKM 317.5), kidney (RPKM 253.4) and 23 other tissues See more Orthologs mouse all