AGRP, Official Symbol AGRPprovided by HGNC Official Full Name agouti related neuropeptideprovided by HGNC Primary source HGNC:HGNC:330 See related Ensembl:ENSG00000159723 MIM:602311; AllianceGenome:HGNC:330 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ART; AGRT; ASIP2 Summary This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009] Expression Biased expression in adrenal (RPKM 1.6), lung (RPKM 0.8) and 5 other tissues See more Orthologs mouse all