CCL28, Official Symbol CCL28provided by HGNC Official Full Name C-C motif chemokine ligand 28provided by HGNC Primary source HGNC:HGNC:17700 See related Ensembl:ENSG00000151882 MIM:605240; AllianceGenome:HGNC:17700 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MEC; CCK1; SCYA28 Summary This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2014] Expression Biased expression in salivary gland (RPKM 40.6), colon (RPKM 10.6) and 5 other tissues See more Orthologs mouse all