FBXO45, Official Symbol FBXO45provided by HGNC Official Full Name F-box protein 45provided by HGNC Primary source HGNC:HGNC:29148 See related Ensembl:ENSG00000174013 MIM:609112; AllianceGenome:HGNC:29148 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx45 Summary Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Jan 2011] Expression Ubiquitous expression in brain (RPKM 6.3), testis (RPKM 6.3) and 25 other tissues See more Orthologs mouse all