MAP4K1, Official Symbol MAP4K1provided by HGNC Official Full Name mitogen-activated protein kinase kinase kinase kinase 1provided by HGNC Primary source HGNC:HGNC:6863 See related Ensembl:ENSG00000104814 MIM:601983; AllianceGenome:HGNC:6863 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPK1 Summary Enables ATP binding activity and MAP kinase kinase kinase kinase activity. Involved in several processes, including JNK cascade; cellular response to phorbol 13-acetate 12-myristate; and protein phosphorylation. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in lymph node (RPKM 28.4), spleen (RPKM 19.4) and 10 other tissues See more Orthologs mouse all