SLC5A8, Official Symbol SLC5A8provided by HGNC Official Full Name solute carrier family 5 member 8provided by HGNC Primary source HGNC:HGNC:19119 See related Ensembl:ENSG00000256870 MIM:608044; AllianceGenome:HGNC:19119 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIT; SMCT; SMCT1 Summary SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al., 2006 [PubMed 16873376]).[supplied by OMIM, Dec 2008] Expression Biased expression in thyroid (RPKM 19.8), kidney (RPKM 2.8) and 1 other tissue See more Orthologs mouse all