BNIP3L, Official Symbol BNIP3Lprovided by HGNC Official Full Name BCL2 interacting protein 3 likeprovided by HGNC Primary source HGNC:HGNC:1085 See related Ensembl:ENSG00000104765 MIM:605368; AllianceGenome:HGNC:1085 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIX; NIP3L; BNIP3a Summary This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015] Expression Ubiquitous expression in fat (RPKM 69.4), ovary (RPKM 49.9) and 24 other tissues See more Orthologs mouse all