IRX3, Official Symbol IRX3provided by HGNC Official Full Name iroquois homeobox 3provided by HGNC Primary source HGNC:HGNC:14360 See related Ensembl:ENSG00000177508 MIM:612985; AllianceGenome:HGNC:14360 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IRX-1; IRXB1 Summary IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009] Expression Biased expression in lung (RPKM 13.1), skin (RPKM 8.6) and 10 other tissues See more Orthologs mouse all