RTN4IP1, Official Symbol RTN4IP1provided by HGNC Official Full Name reticulon 4 interacting protein 1provided by HGNC Primary source HGNC:HGNC:18647 See related Ensembl:ENSG00000130347 MIM:610502; AllianceGenome:HGNC:18647 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NIMP; OPA10 Summary This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, cognitive disability, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in skin (RPKM 10.5), placenta (RPKM 7.8) and 24 other tissues See more Orthologs mouse all