TRIM24, Official Symbol TRIM24provided by HGNC Official Full Name tripartite motif containing 24provided by HGNC Primary source HGNC:HGNC:11812 See related Ensembl:ENSG00000122779 MIM:603406; AllianceGenome:HGNC:11812 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA Summary The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 19.9), ovary (RPKM 16.3) and 25 other tissues See more Orthologs mouse all