NCS1, Official Symbol NCS1provided by HGNC Official Full Name neuronal calcium sensor 1provided by HGNC Primary source HGNC:HGNC:3953 See related Ensembl:ENSG00000107130 MIM:603315; AllianceGenome:HGNC:3953 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FLUP; FREQ Summary This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 60.4), esophagus (RPKM 14.4) and 11 other tissues See more Orthologs mouse all