CEACAM6, Official Symbol CEACAM6provided by HGNC Official Full Name CEA cell adhesion molecule 6provided by HGNC Primary source HGNC:HGNC:1818 See related Ensembl:ENSG00000086548 MIM:163980; AllianceGenome:HGNC:1818 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCA; CEAL; CD66c; NCA-50/90 Summary This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014] Expression Biased expression in colon (RPKM 147.4), lung (RPKM 142.2) and 9 other tissues See more Orthologs all