MCF2, Official Symbol MCF2provided by HGNC Official Full Name MCF.2 cell line derived transforming sequenceprovided by HGNC Primary source HGNC:HGNC:6940 See related Ensembl:ENSG00000101977 MIM:311030; AllianceGenome:HGNC:6940 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DBL; ARHGEF21 Summary The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.[provided by RefSeq, Jan 2010] Expression Biased expression in adrenal (RPKM 10.3), testis (RPKM 7.9) and 2 other tissues See more Orthologs mouse all