GATA4, Official Symbol GATA4provided by HGNC Official Full Name GATA binding protein 4provided by HGNC Primary source HGNC:HGNC:4173 See related Ensembl:ENSG00000136574 MIM:600576; AllianceGenome:HGNC:4173 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TOF; ASD2; VSD1; TACHD Summary This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] Expression Biased expression in ovary (RPKM 23.7), duodenum (RPKM 16.4) and 8 other tissues See more Orthologs mouse all