KYAT1, Official Symbol KYAT1provided by HGNC Official Full Name kynurenine aminotransferase 1provided by HGNC Primary source HGNC:HGNC:1564 See related Ensembl:ENSG00000171097 MIM:600547; AllianceGenome:HGNC:1564 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GTK; KAT1; KATI; CCBL1 Summary This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 2.6), skin (RPKM 1.9) and 25 other tissues See more Orthologs mouse all