LSM4, Official Symbol LSM4provided by HGNC Official Full Name LSM4 homolog, U6 small nuclear RNA and mRNA degradation associatedprovided by HGNC Primary source HGNC:HGNC:17259 See related Ensembl:ENSG00000130520 MIM:607284; AllianceGenome:HGNC:17259 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GRP; YER112W Summary This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] Expression Ubiquitous expression in testis (RPKM 22.8), colon (RPKM 19.7) and 25 other tissues See more Orthologs mouse all