DHDH, Official Symbol DHDHprovided by HGNC Official Full Name dihydrodiol dehydrogenaseprovided by HGNC Primary source HGNC:HGNC:17887 See related Ensembl:ENSG00000104808 MIM:606377; AllianceGenome:HGNC:17887 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 2DD; HUM2DD Summary This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 7.4), small intestine (RPKM 4.3) and 5 other tissues See more Orthologs mouse all