XAGE1B, Official Symbol XAGE1Bprovided by HGNC Official Full Name X antigen family member 1Bprovided by HGNC Primary source HGNC:HGNC:25400 See related Ensembl:ENSG00000204382 MIM:300289; AllianceGenome:HGNC:25400 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CTP9; XAGE1; CT12.1; GAGED2; XAGE-1; XAGE1C; XAGE1D; XAGE1E; CT12.1C; CT12.1D; CT12.1E; CT12.1b Summary This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010] Annotation information Note: There are two XAGE1 loci on the X chromosome. This location, previously annotated as XAGE1E, is now annotated as XAGE1B. [01 Dec 2017] Expression Restricted expression toward testis (RPKM 23.6) See more Orthologs all