ASB14, Official Symbol ASB14provided by HGNC Official Full Name ankyrin repeat and SOCS box containing 14provided by HGNC Primary source HGNC:HGNC:19766 See related Ensembl:ENSG00000239388 AllianceGenome:HGNC:19766 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2008] Expression Ubiquitous expression in heart (RPKM 1.8), bone marrow (RPKM 1.0) and 25 other tissues See more Orthologs mouse all