CYSLTR2, Official Symbol CYSLTR2provided by HGNC Official Full Name cysteinyl leukotriene receptor 2provided by HGNC Primary source HGNC:HGNC:18274 See related Ensembl:ENSG00000152207 MIM:605666; AllianceGenome:HGNC:18274 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HG57; CYSLT2; GPCR21; HPN321; CYSLT2R; KPG_011; hGPCR21; PSEC0146 Summary The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008] Expression Broad expression in placenta (RPKM 7.8), heart (RPKM 2.8) and 17 other tissues See more Orthologs mouse all