XAGE3, Official Symbol XAGE3provided by HGNC Official Full Name X antigen family member 3provided by HGNC Primary source HGNC:HGNC:14618 See related Ensembl:ENSG00000171402 MIM:300740; AllianceGenome:HGNC:14618 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PLAC6; GAGED4; XAGE-3; pp9012; CT12.3a; CT12.3b Summary This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008] Expression Restricted expression toward placenta (RPKM 81.9) See more Orthologs all