CLDN2, Official Symbol CLDN2provided by HGNC Official Full Name claudin 2provided by HGNC Primary source HGNC:HGNC:2041 See related Ensembl:ENSG00000165376 MIM:300520; AllianceGenome:HGNC:2041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OAZON; claudin-2 Summary This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010] Expression Biased expression in kidney (RPKM 67.4), gall bladder (RPKM 59.4) and 4 other tissues See more Orthologs mouse all