SLC22A1, Official Symbol SLC22A1provided by HGNC Official Full Name solute carrier family 22 member 1provided by HGNC Primary source HGNC:HGNC:10963 See related Ensembl:ENSG00000175003 MIM:602607; AllianceGenome:HGNC:10963 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OCT1; HOCT1; oct1_cds Summary Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008] Expression Restricted expression toward liver (RPKM 121.5) See more Orthologs all