PELI1, Official Symbol PELI1provided by HGNC Official Full Name pellino E3 ubiquitin protein ligase 1provided by HGNC Primary source HGNC:HGNC:8827 See related Ensembl:ENSG00000197329 MIM:614797; AllianceGenome:HGNC:8827 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin protein ligase activity. Involved in several processes, including negative regulation of necroptotic process; protein polyubiquitination; and response to lipopolysaccharide. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 57.0), esophagus (RPKM 14.7) and 19 other tissues See more Orthologs mouse all