RPS6KB2, Official Symbol RPS6KB2provided by HGNC Official Full Name ribosomal protein S6 kinase B2provided by HGNC Primary source HGNC:HGNC:10437 See related Ensembl:ENSG00000175634 MIM:608939; AllianceGenome:HGNC:10437 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KLS; SRK; S6K2; S6KB; STK14B; S6KI(2); S6Kbeta; p70S6Kb; P70-beta; S6K-beta2; P70-beta-1; P70-beta-2; p70(S6K)-beta Summary This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015] Expression Ubiquitous expression in skin (RPKM 31.3), esophagus (RPKM 20.5) and 25 other tissues See more Orthologs mouse all