SOX18, Official Symbol SOX18provided by HGNC Official Full Name SRY-box transcription factor 18provided by HGNC Primary source HGNC:HGNC:11194 See related Ensembl:ENSG00000203883 MIM:601618; AllianceGenome:HGNC:11194 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HLTS; HLTRS Summary This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq, Jul 2008] Expression Biased expression in fat (RPKM 25.4), kidney (RPKM 7.2) and 9 other tissues See more Orthologs mouse all