DBN1, Official Symbol DBN1provided by HGNC Official Full Name drebrin 1provided by HGNC Primary source HGNC:HGNC:2695 See related Ensembl:ENSG00000113758 MIM:126660; AllianceGenome:HGNC:2695 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as D0S117E Summary The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in endometrium (RPKM 21.1), brain (RPKM 16.5) and 24 other tissues See more Orthologs mouse all