PBX2, Official Symbol PBX2provided by HGNC Official Full Name PBX homeobox 2provided by HGNC Primary source HGNC:HGNC:8633 See related Ensembl:ENSG00000204304 MIM:176311; AllianceGenome:HGNC:8633 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G17; HOX12; PBX2MHC Summary This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in placenta (RPKM 34.1), spleen (RPKM 33.9) and 25 other tissues See more Orthologs mouse all