RUFY4, Official Symbol RUFY4provided by HGNC Official Full Name RUN and FYVE domain containing 4provided by HGNC Primary source HGNC:HGNC:24804 See related Ensembl:ENSG00000188282 AllianceGenome:HGNC:24804 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZFYVE31 Summary Enables phosphatidylinositol-3-phosphate binding activity. Involved in autophagosome assembly; cellular response to interleukin-4; and positive regulation of macroautophagy. Located in autophagosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 1.0), lymph node (RPKM 0.6) and 16 other tissues See more Orthologs mouse all