RNF183, Official Symbol RNF183provided by HGNC Official Full Name ring finger protein 183provided by HGNC Primary source HGNC:HGNC:28721 See related Ensembl:ENSG00000165188 AllianceGenome:HGNC:28721 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables ubiquitin protein ligase activity. Involved in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; protein ubiquitination; and response to endoplasmic reticulum stress. Located in endoplasmic reticulum. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in gall bladder (RPKM 1.5), kidney (RPKM 1.3) and 7 other tissues See more Orthologs mouse all