ULBP3, Official Symbol ULBP3provided by HGNC Official Full Name UL16 binding protein 3provided by HGNC Primary source HGNC:HGNC:14895 See related Ensembl:ENSG00000131019 MIM:605699; AllianceGenome:HGNC:14895 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as N2DL-3; RAET1N; NKG2DL3 Summary The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics. [provided by RefSeq, Nov 2015] Expression Broad expression in testis (RPKM 3.9), thyroid (RPKM 2.5) and 17 other tissues See more Orthologs all