KYNU, Official Symbol KYNUprovided by HGNC Official Full Name kynureninaseprovided by HGNC Primary source HGNC:HGNC:6469 See related Ensembl:ENSG00000115919 MIM:605197; AllianceGenome:HGNC:6469 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KYNUU; VCRL2 Summary Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010] Expression Broad expression in liver (RPKM 2.5), urinary bladder (RPKM 1.8) and 14 other tissues See more Orthologs mouse all