SRPK1, Official Symbol SRPK1provided by HGNC Official Full Name SRSF protein kinase 1provided by HGNC Primary source HGNC:HGNC:11305 See related Ensembl:ENSG00000096063 MIM:601939; AllianceGenome:HGNC:11305 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SFRSK1 Summary This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.[provided by RefSeq, Jul 2010] Expression Broad expression in testis (RPKM 31.4), bone marrow (RPKM 17.2) and 25 other tissues See more Orthologs mouse all