DGKD, Official Symbol DGKDprovided by HGNC Official Full Name diacylglycerol kinase deltaprovided by HGNC Primary source HGNC:HGNC:2851 See related Ensembl:ENSG00000077044 MIM:601826; AllianceGenome:HGNC:2851 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dgkd-2; DGKdelta; DGK-delta Summary This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Broad expression in stomach (RPKM 11.9), bone marrow (RPKM 9.9) and 23 other tissues See more Orthologs mouse all