TRH, Official Symbol TRHprovided by HGNC Official Full Name thyrotropin releasing hormoneprovided by HGNC Primary source HGNC:HGNC:12298 See related Ensembl:ENSG00000170893 MIM:613879; AllianceGenome:HGNC:12298 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRF; Pro-TRH Summary This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013] Expression Biased expression in endometrium (RPKM 11.5), bone marrow (RPKM 1.1) and 1 other tissue See more Orthologs mouse all