POLD1, Official Symbol POLD1provided by HGNC Official Full Name DNA polymerase delta 1, catalytic subunitprovided by HGNC Primary source HGNC:HGNC:9175 See related Ensembl:ENSG00000062822 MIM:174761; AllianceGenome:HGNC:9175 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDC2; MDPL; POLD; CRCS10 Summary This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012] Expression Broad expression in bone marrow (RPKM 7.5), testis (RPKM 4.7) and 24 other tissues See more Orthologs mouse all