CGNL1, Official Symbol CGNL1provided by HGNC Official Full Name cingulin like 1provided by HGNC Primary source HGNC:HGNC:25931 See related Ensembl:ENSG00000128849 MIM:607856; AllianceGenome:HGNC:25931 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JACOP; PCING Summary This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011] Expression Broad expression in kidney (RPKM 42.7), prostate (RPKM 13.0) and 15 other tissues See more Orthologs mouse all