AP2A2, Official Symbol AP2A2provided by HGNC Official Full Name adaptor related protein complex 2 subunit alpha 2provided by HGNC Primary source HGNC:HGNC:562 See related Ensembl:ENSG00000183020 MIM:607242; AllianceGenome:HGNC:562 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HIP9; HYPJ; ADTAB; HIP-9; CLAPA2 Summary The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016] Expression Ubiquitous expression in spleen (RPKM 30.8), brain (RPKM 22.0) and 25 other tissues See more Orthologs mouse all