FAF1, Official Symbol FAF1provided by HGNC Official Full Name Fas associated factor 1provided by HGNC Primary source HGNC:HGNC:3578 See related Ensembl:ENSG00000185104 MIM:604460; AllianceGenome:HGNC:3578 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hFAF1; CGI-03; HFAF1s; UBXD12; UBXN3A Summary Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 31.0), thyroid (RPKM 14.4) and 25 other tissues See more Orthologs mouse all