ID3, Official Symbol ID3provided by HGNC Official Full Name inhibitor of DNA binding 3provided by HGNC Primary source HGNC:HGNC:5362 See related Ensembl:ENSG00000117318 MIM:600277; AllianceGenome:HGNC:5362 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEIR-1; bHLHb25 Summary The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011] Expression Broad expression in thyroid (RPKM 81.9), prostate (RPKM 51.6) and 21 other tissues See more Orthologs mouse all