S100A12, Official Symbol S100A12provided by HGNC Official Full Name S100 calcium binding protein A12provided by HGNC Primary source HGNC:HGNC:10489 See related Ensembl:ENSG00000163221 MIM:603112; AllianceGenome:HGNC:10489 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p6; CAGC; CGRP; MRP6; CAAF1; MRP-6; ENRAGE Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity. [provided by RefSeq, Nov 2014] Expression Restricted expression toward bone marrow (RPKM 747.5) See more Orthologs all