SH2D1B, Official Symbol SH2D1Bprovided by HGNC Official Full Name SH2 domain containing 1Bprovided by HGNC Primary source HGNC:HGNC:30416 See related Ensembl:ENSG00000198574 MIM:608510; AllianceGenome:HGNC:30416 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EAT2 Summary By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008] Expression Broad expression in spleen (RPKM 4.0), bone marrow (RPKM 1.8) and 14 other tissues See more Orthologs all