AMELX, Official Symbol AMELXprovided by HGNC Official Full Name amelogenin X-linkedprovided by HGNC Primary source HGNC:HGNC:461 See related Ensembl:ENSG00000125363 MIM:300391; AllianceGenome:HGNC:461 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AMG; AI1E; AIH1; ALGN; AMGL; AMGX Summary This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all