KISS1R, Official Symbol KISS1Rprovided by HGNC Official Full Name KISS1 receptorprovided by HGNC Primary source HGNC:HGNC:4510 See related Ensembl:ENSG00000116014 MIM:604161; AllianceGenome:HGNC:4510 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HH8; CPPB1; GPR54; AXOR12; KISS-1R; HOT7T175 Summary The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all