PLA2G12A, Official Symbol PLA2G12Aprovided by HGNC Official Full Name phospholipase A2 group XIIAprovided by HGNC Primary source HGNC:HGNC:18554 See related Ensembl:ENSG00000123739 MIM:611652; AllianceGenome:HGNC:18554 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GXII; ROSSY; PLA2G12 Summary Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in thyroid (RPKM 11.6), prostate (RPKM 9.6) and 25 other tissues See more Orthologs mouse all