TMEM59, Official Symbol TMEM59provided by HGNC Official Full Name transmembrane protein 59provided by HGNC Primary source HGNC:HGNC:1239 See related Ensembl:ENSG00000116209 MIM:617084; AllianceGenome:HGNC:1239 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DCF1; C1orf8; PRO195; UNQ169; HSPC001 Summary This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] Expression Ubiquitous expression in colon (RPKM 47.8), prostate (RPKM 39.1) and 25 other tissues See more Orthologs mouse all