CDC42EP3, Official Symbol CDC42EP3provided by HGNC Official Full Name CDC42 effector protein 3provided by HGNC Primary source HGNC:HGNC:16943 See related Ensembl:ENSG00000163171 MIM:606133; AllianceGenome:HGNC:16943 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UB1; CEP3; BORG2 Summary This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] Expression Broad expression in prostate (RPKM 28.7), endometrium (RPKM 27.8) and 23 other tissues See more Orthologs mouse all