GKN2, Official Symbol GKN2provided by HGNC Official Full Name gastrokine 2provided by HGNC Primary source HGNC:HGNC:24588 See related Ensembl:ENSG00000183607 MIM:618589; AllianceGenome:HGNC:24588 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GDDR; TFIZ1; PRO813; BRICD1B; VLTI465 Summary The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015] Expression Restricted expression toward stomach (RPKM 1463.9) See more Orthologs mouse all