TNKS, Official Symbol TNKSprovided by HGNC Official Full Name tankyraseprovided by HGNC Primary source HGNC:HGNC:11941 See related Ensembl:ENSG00000173273 MIM:603303; AllianceGenome:HGNC:11941 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIN1; ARTD5; PARPL; TINF1; TNKS1; pART5; PARP5A; PARP-5a Summary Enables histone binding activity; pentosyltransferase activity; and zinc ion binding activity. Involved in several processes, including negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric; protein ADP-ribosylation; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and protein ADP-ribosylation. Located in several cellular components, including chromosome, telomeric region; mitotic spindle pole; and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 8.6), brain (RPKM 7.0) and 25 other tissues See more Orthologs mouse all