ISYNA1, Official Symbol ISYNA1provided by HGNC Official Full Name inositol-3-phosphate synthase 1provided by HGNC Primary source HGNC:HGNC:29821 See related Ensembl:ENSG00000105655 MIM:611670; AllianceGenome:HGNC:29821 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IPS; INO1; INOS; IPS 1; IPS-1 Summary This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011] Expression Broad expression in testis (RPKM 72.6), placenta (RPKM 57.0) and 14 other tissues See more Orthologs mouse all