SMARCA5, Official Symbol SMARCA5provided by HGNC Official Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5provided by HGNC Primary source HGNC:HGNC:11101 See related Ensembl:ENSG00000153147 MIM:603375; AllianceGenome:HGNC:11101 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ISWI; SNF2H; hISWI; hSNF2H; WCRF135 Summary The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 25.1), lung (RPKM 17.3) and 25 other tissues See more Orthologs mouse all