TBC1D10B, Official Symbol TBC1D10Bprovided by HGNC Official Full Name TBC1 domain family member 10Bprovided by HGNC Primary source HGNC:HGNC:24510 See related Ensembl:ENSG00000169221 MIM:613620; AllianceGenome:HGNC:24510 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPI64B; FP2461 Summary Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010] Expression Ubiquitous expression in testis (RPKM 19.6), brain (RPKM 12.7) and 25 other tissues See more Orthologs mouse all