LYRM7, Official Symbol LYRM7provided by HGNC Official Full Name LYR motif containing 7provided by HGNC Primary source HGNC:HGNC:28072 See related Ensembl:ENSG00000186687 MIM:615831; AllianceGenome:HGNC:28072 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MZM1L; MC3DN8; C5orf31 Summary Inner mitochondrial membrane complex III (CIII) is the main enzyme complex in the mitochondrial respiratory chain, and Rieske Fe-S protein (UQCRFS1) is the last catalytic subunit added to the complex. The protein encoded by this gene is a nuclear-encoded mitochondrial matrix protein that stabilizes UQCRFS1 and chaperones it to the CIII complex. Defects in this gene are a cause of mitochondrial complex III deficiency, nuclear type 8. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] Expression Ubiquitous expression in brain (RPKM 5.8), thyroid (RPKM 4.7) and 24 other tissues See more Orthologs mouse all