SHLD2, Official Symbol SHLD2provided by HGNC Official Full Name shieldin complex subunit 2provided by HGNC Primary source HGNC:HGNC:28773 See related Ensembl:ENSG00000122376 MIM:618029; AllianceGenome:HGNC:28773 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RINN2; FAM35A; FAM35A1; bA163M19.1 Summary Involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Located in nucleus and site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 20.9), thyroid (RPKM 14.9) and 25 other tissues See more Orthologs mouse all