EMC3, Official Symbol EMC3provided by HGNC Official Full Name ER membrane protein complex subunit 3provided by HGNC Primary source HGNC:HGNC:23999 See related Ensembl:ENSG00000125037 MIM:620273; AllianceGenome:HGNC:23999 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as POB; TMEM111 Summary Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Is integral component of endoplasmic reticulum membrane. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 29.9), testis (RPKM 23.1) and 25 other tissues See more Orthologs mouse all