SETD4, Official Symbol SETD4provided by HGNC Official Full Name SET domain containing 4provided by HGNC Primary source HGNC:HGNC:1258 See related Ensembl:ENSG00000185917 AllianceGenome:HGNC:1258 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C21orf18; C21orf27 Summary Enables histone methyltransferase activity (H4-K20 specific). Involved in histone H4-K20 trimethylation. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 7.1), skin (RPKM 4.7) and 25 other tissues See more Orthologs mouse all