POLI, Official Symbol POLIprovided by HGNC Official Full Name DNA polymerase iotaprovided by HGNC Primary source HGNC:HGNC:9182 See related Ensembl:ENSG00000101751 MIM:605252; AllianceGenome:HGNC:9182 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as eta2; RAD30B; RAD3OB Summary The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. [provided by RefSeq, May 2017] Expression Ubiquitous expression in thyroid (RPKM 9.1), testis (RPKM 7.6) and 25 other tissues See more Orthologs mouse all