GSTT2B, Official Symbol GSTT2Bprovided by HGNC Official Full Name glutathione S-transferase theta 2Bprovided by HGNC Primary source HGNC:HGNC:33437 See related Ensembl:ENSG00000133433 AllianceGenome:HGNC:33437 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GSTT2P Summary The protein encoded by this gene, glutathione S-transferase (GST) theta 2B (GSTT2B), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2B gene is a pseudogene in some populations. [provided by RefSeq, Sep 2015] Annotation information Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene. Expression Broad expression in adrenal (RPKM 23.9), skin (RPKM 19.2) and 21 other tissues See more Orthologs all