HTR5A, Official Symbol HTR5Aprovided by HGNC Official Full Name 5-hydroxytryptamine receptor 5Aprovided by HGNC Primary source HGNC:HGNC:5300 See related Ensembl:ENSG00000157219 MIM:601305; AllianceGenome:HGNC:5300 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 5-HT5A Summary The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008] Expression Restricted expression toward brain (RPKM 2.3) See more Orthologs mouse all