SNRPE, Official Symbol SNRPEprovided by HGNC Official Full Name small nuclear ribonucleoprotein polypeptide Eprovided by HGNC Primary source HGNC:HGNC:11161 See related Ensembl:ENSG00000182004 MIM:128260; AllianceGenome:HGNC:11161 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SME; Sm-E; HYPT11; snRNP-E Summary The protein encoded by this gene is a core component of U small nuclear ribonucleoproteins, which are key components of the pre-mRNA processing spliceosome. The encoded protein plays a role in the 3' end processing of histone transcripts. This protein is one of the targets in the autoimmune disease systemic lupus erythematosus, and mutations in this gene have been associated with hypotrichosis. Several pseudogenes of this gene have been identified. [provided by RefSeq, Jun 2016] Expression Ubiquitous expression in colon (RPKM 16.8), ovary (RPKM 16.5) and 25 other tissues See more Orthologs mouse all