NAP1L4, Official Symbol NAP1L4provided by HGNC Official Full Name nucleosome assembly protein 1 like 4provided by HGNC Primary source HGNC:HGNC:7640 See related Ensembl:ENSG00000205531 MIM:601651; AllianceGenome:HGNC:7640 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAP2; NAP2L; hNAP2; NAP1L4b Summary This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 52.4), heart (RPKM 37.7) and 25 other tissues See more Orthologs mouse all