GRK5, Official Symbol GRK5provided by HGNC Official Full Name G protein-coupled receptor kinase 5provided by HGNC Primary source HGNC:HGNC:4544 See related Ensembl:ENSG00000198873 MIM:600870; AllianceGenome:HGNC:4544 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPRK5; FP2025 Summary This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lung (RPKM 30.9), spleen (RPKM 17.1) and 23 other tissues See more Orthologs mouse all