FRMPD3, Official Symbol FRMPD3provided by HGNC Official Full Name FERM and PDZ domain containing 3provided by HGNC Primary source HGNC:HGNC:29382 See related Ensembl:ENSG00000147234 MIM:301005; AllianceGenome:HGNC:29382 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a protein that contains a PDZ (post synaptic density protein (PSD95), Drosophila disc large tumor suppressor (Dlg1), and zonula occludens-1 protein (zo-1) domain at the N-terminus followed by a FERM domain. The encoded protein is involved in signal transduction. The PDZ domain is thought to function in protein-protein interactions, mainly by binding to specific C-terminal peptides of other proteins. The FERM domain is found in proteins that are localized to the plasma membrane and are associated with the cytoskeleton. [provided by RefSeq, May 2017] Expression Biased expression in ovary (RPKM 3.1), brain (RPKM 2.3) and 8 other tissues See more Orthologs mouse all