CDC7, Official Symbol CDC7provided by HGNC Official Full Name cell division cycle 7provided by HGNC Primary source HGNC:HGNC:1745 See related Ensembl:ENSG00000097046 MIM:603311; AllianceGenome:HGNC:1745 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Hsk1; CDC7L1; HsCDC7; huCDC7 Summary This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008] Expression Broad expression in testis (RPKM 10.5), lymph node (RPKM 4.8) and 19 other tissues See more Orthologs mouse all