ZBTB16, Official Symbol ZBTB16provided by HGNC Official Full Name zinc finger and BTB domain containing 16provided by HGNC Primary source HGNC:HGNC:12930 See related Ensembl:ENSG00000109906 MIM:176797; AllianceGenome:HGNC:12930 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PLZF; ZNF145 Summary This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] Expression Broad expression in fat (RPKM 27.9), ovary (RPKM 22.2) and 19 other tissues See more Orthologs mouse all