EGLN2, Official Symbol EGLN2provided by HGNC Official Full Name egl-9 family hypoxia inducible factor 2provided by HGNC Primary source HGNC:HGNC:14660 See related Ensembl:ENSG00000269858 MIM:606424; AllianceGenome:HGNC:14660 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EIT6; PHD1; EIT-6; HPH-1; HPH-3; HIFPH1; HIF-PH1 Summary The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011] Expression Broad expression in testis (RPKM 61.2), spleen (RPKM 33.0) and 24 other tissues See more Orthologs mouse all