SHBG, Official Symbol SHBGprovided by HGNC Official Full Name sex hormone binding globulinprovided by HGNC Primary source HGNC:HGNC:10839 See related Ensembl:ENSG00000129214 MIM:182205; AllianceGenome:HGNC:10839 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ABP; SBP; TEBG Summary This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] Expression Biased expression in liver (RPKM 11.7), testis (RPKM 2.8) and 3 other tissues See more Orthologs mouse all