KIF1B, Official Symbol KIF1Bprovided by HGNC Official Full Name kinesin family member 1Bprovided by HGNC Primary source HGNC:HGNC:16636 See related Ensembl:ENSG00000054523 MIM:605995; AllianceGenome:HGNC:16636 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KLP; CMT2; CMT2A; CMT2A1; HMSNII; NBLST1 Summary Predicted to enable microtubule binding activity and plus-end-directed microtubule motor activity. Predicted to be involved in chemical synaptic transmission; dense core granule cytoskeletal transport; and vesicle-mediated transport. Predicted to act upstream of or within mitochondrion transport along microtubule. Predicted to be located in cytoplasmic vesicle membrane and neuron projection. Predicted to be part of kinesin complex. Predicted to be active in several cellular components, including axon; dendrite; and microtubule. Implicated in Charcot-Marie-Tooth disease type 2A1; carcinoma (multiple); multiple sclerosis; neuroblastoma; and pheochromocytoma. Biomarker of hepatocellular carcinoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 28.3), testis (RPKM 7.8) and 23 other tissues See more Orthologs mouse all