ARHGAP23, Official Symbol ARHGAP23provided by HGNC Official Full Name Rho GTPase activating protein 23provided by HGNC Primary source HGNC:HGNC:29293 See related Ensembl:ENSG00000275832 MIM:610590; AllianceGenome:HGNC:29293 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008] Expression Broad expression in skin (RPKM 13.7), brain (RPKM 13.2) and 22 other tissues See more Orthologs mouse all