TFAP2C, Official Symbol TFAP2Cprovided by HGNC Official Full Name transcription factor AP-2 gammaprovided by HGNC Primary source HGNC:HGNC:11744 See related Ensembl:ENSG00000087510 MIM:601602; AllianceGenome:HGNC:11744 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ERF1; TFAP2G; hAP-2g; AP2-GAMMA Summary The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008] Expression Biased expression in skin (RPKM 24.1), placenta (RPKM 10.9) and 6 other tissues See more Orthologs mouse all