TAC1, Official Symbol TAC1provided by HGNC Official Full Name tachykinin precursor 1provided by HGNC Primary source HGNC:HGNC:11517 See related Ensembl:ENSG00000006128 MIM:162320; AllianceGenome:HGNC:11517 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NK2; NPK; NKNA; TAC2; Hs.2563 Summary This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014] Expression Biased expression in brain (RPKM 24.6), spleen (RPKM 12.4) and 6 other tissues See more Orthologs mouse all