RGP1, Official Symbol RGP1provided by HGNC Official Full Name RGP1 homolog, RAB6A GEF complex partner 1provided by HGNC Primary source HGNC:HGNC:21965 See related Ensembl:ENSG00000107185 MIM:615742; AllianceGenome:HGNC:21965 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KIAA0258 Summary Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in negative regulation of cellular protein catabolic process; positive regulation of GTPase activity; and retrograde transport, endosome to Golgi. Located in cytosol and plasma membrane. Part of Ric1-Rgp1 guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 11.4), kidney (RPKM 9.6) and 25 other tissues See more Orthologs mouse all