LRCH2, Official Symbol LRCH2provided by HGNC Official Full Name leucine rich repeats and calponin homology domain containing 2provided by HGNC Primary source HGNC:HGNC:29292 See related Ensembl:ENSG00000130224 AllianceGenome:HGNC:29292 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as dA204F4.4 Summary This gene encodes a member of the leucine-rich repeat and calponin homology domain-containing protein family. These family members contain multiple N-terminal leucine-rich repeats, in addition to a C-terminal calponin homology domain, a type of domain that mediates interactions with actin filaments. These proteins are conserved across animal species, and studies of a similar Drosophila protein indicate a function as a cytoskeletal scaffolding protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011] Expression Broad expression in prostate (RPKM 3.7), brain (RPKM 2.9) and 20 other tissues See more Orthologs mouse all