PFKP, Official Symbol PFKPprovided by HGNC Official Full Name phosphofructokinase, plateletprovided by HGNC Primary source HGNC:HGNC:8878 See related Ensembl:ENSG00000067057 MIM:171840; AllianceGenome:HGNC:8878 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PFKF; PFK-C; PFK-P; ATP-PFK Summary This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] Expression Broad expression in testis (RPKM 49.8), brain (RPKM 37.5) and 23 other tissues See more Orthologs mouse all