PRTN3, Official Symbol PRTN3provided by HGNC Official Full Name proteinase 3provided by HGNC Primary source HGNC:HGNC:9495 See related Ensembl:ENSG00000196415 MIM:177020; AllianceGenome:HGNC:9495 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA Summary Enables enzyme binding activity; serine-type endopeptidase activity; and signaling receptor binding activity. Involved in several processes, including mature conventional dendritic cell differentiation; membrane protein ectodomain proteolysis; and neutrophil extravasation. Located in azurophil granule lumen; cytosol; and plasma membrane raft. Colocalizes with plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Restricted expression toward bone marrow (RPKM 616.2) See more Orthologs mouse all