ZFYVE27, Official Symbol ZFYVE27provided by HGNC Official Full Name zinc finger FYVE-type containing 27provided by HGNC Primary source HGNC:HGNC:26559 See related Ensembl:ENSG00000155256 MIM:610243; AllianceGenome:HGNC:26559 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPG33; PROTRUDIN Summary This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010] Expression Ubiquitous expression in small intestine (RPKM 6.9), duodenum (RPKM 6.9) and 25 other tissues See more Orthologs mouse all