PLK1, Official Symbol PLK1provided by HGNC Official Full Name polo like kinase 1provided by HGNC Primary source HGNC:HGNC:9077 See related Ensembl:ENSG00000166851 MIM:602098; AllianceGenome:HGNC:9077 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PLK; STPK13 Summary The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015] Expression Biased expression in testis (RPKM 20.5), lymph node (RPKM 15.8) and 13 other tissues See more Orthologs mouse all