OLFML3, Official Symbol OLFML3provided by HGNC Official Full Name olfactomedin like 3provided by HGNC Primary source HGNC:HGNC:24956 See related Ensembl:ENSG00000116774 MIM:610088; AllianceGenome:HGNC:24956 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OLF44; HNOEL-iso Summary This gene encodes a member of the olfactomedin-like gene family which also includes genes encoding noelin, tiarin, myocilin, amassin, optimedin, photomedin, and latrophilin. The encoded protein is a secreted extracellular matrix glycoprotein with a C-terminal olfactomedin domain that facilitates protein-protein interactions, cell adhesion, and intercellular interactions. It serves as both a scaffold protein that recruits bone morphogenetic protein 1 to its substrate chordin, and as a vascular tissue remodeler with pro-angiogenic properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] Expression Broad expression in ovary (RPKM 65.9), endometrium (RPKM 56.6) and 23 other tissues See more Orthologs mouse all