ARSB, Official Symbol ARSBprovided by HGNC Official Full Name arylsulfatase Bprovided by HGNC Primary source HGNC:HGNC:714 See related Ensembl:ENSG00000113273 MIM:611542; AllianceGenome:HGNC:714 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ASB; G4S; MPS6 Summary Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2016] Expression Ubiquitous expression in kidney (RPKM 2.5), placenta (RPKM 1.5) and 25 other tissues See more Orthologs mouse all