SMTN, Official Symbol SMTNprovided by HGNC Official Full Name smoothelinprovided by HGNC Primary source HGNC:HGNC:11126 See related Ensembl:ENSG00000183963 MIM:602127; AllianceGenome:HGNC:11126 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2011] Expression Broad expression in prostate (RPKM 39.0), endometrium (RPKM 30.0) and 20 other tissues See more Orthologs mouse all