MERTK, Official Symbol MERTKprovided by HGNC Official Full Name MER proto-oncogene, tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:7027 See related Ensembl:ENSG00000153208 MIM:604705; AllianceGenome:HGNC:7027 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MER; RP38; c-Eyk; c-mer; Tyro12 Summary This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008] Expression Broad expression in adrenal (RPKM 25.0), spleen (RPKM 11.3) and 21 other tissues See more Orthologs mouse all