MC3R, Official Symbol MC3Rprovided by HGNC Official Full Name melanocortin 3 receptorprovided by HGNC Primary source HGNC:HGNC:6931 See related Ensembl:ENSG00000124089 MIM:155540; AllianceGenome:HGNC:6931 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MC3; OB20; OQTL; BMIQ9; MC3-R Summary This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008] Orthologs mouse all