GK, Official Symbol GKprovided by HGNC Official Full Name glycerol kinaseprovided by HGNC Primary source HGNC:HGNC:4289 See related Ensembl:ENSG00000198814 MIM:300474; AllianceGenome:HGNC:4289 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GK1; GKD Summary The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] Expression Broad expression in kidney (RPKM 27.5), small intestine (RPKM 25.1) and 18 other tissues See more Orthologs mouse all