EIF3E, Official Symbol EIF3Eprovided by HGNC Official Full Name eukaryotic translation initiation factor 3 subunit Eprovided by HGNC Primary source HGNC:HGNC:3277 See related Ensembl:ENSG00000104408 MIM:602210; AllianceGenome:HGNC:3277 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as INT6; EIF3S6; EIF3-P48; eIF3-p46 Summary Enables protein N-terminus binding activity. Contributes to translation initiation factor activity. Involved in positive regulation of mRNA binding activity; regulation of gene expression; and translational initiation. Located in cytosol and nucleus. Part of eukaryotic translation initiation factor 3 complex. Colocalizes with PML body. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 226.7), lymph node (RPKM 138.2) and 25 other tissues See more Orthologs mouse all