KLHL13, Official Symbol KLHL13provided by HGNC Official Full Name kelch like family member 13provided by HGNC Primary source HGNC:HGNC:22931 See related Ensembl:ENSG00000003096 MIM:300655; AllianceGenome:HGNC:22931 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BKLHD2 Summary This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] Expression Broad expression in endometrium (RPKM 9.9), kidney (RPKM 3.7) and 15 other tissues See more Orthologs mouse all