ALG3, Official Symbol ALG3provided by HGNC Official Full Name ALG3 alpha-1,3- mannosyltransferaseprovided by HGNC Primary source HGNC:HGNC:23056 See related Ensembl:ENSG00000214160 MIM:608750; AllianceGenome:HGNC:23056 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as not; CDG1D; CDGS4; CDGS6; Not56; NOT56L; D16Ertd36e Summary This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] Expression Ubiquitous expression in testis (RPKM 10.3), placenta (RPKM 9.7) and 25 other tissues See more Orthologs mouse all