FIS1, Official Symbol FIS1provided by HGNC Official Full Name fission, mitochondrial 1provided by HGNC Primary source HGNC:HGNC:21689 See related Ensembl:ENSG00000214253 MIM:609003; AllianceGenome:HGNC:21689 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTC11; CGI-135 Summary Enables identical protein binding activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; cellular calcium ion homeostasis; and mitochondrion organization. Acts upstream of or within mitochondrion morphogenesis. Located in mitochondrion and peroxisome. Is integral component of mitochondrial outer membrane and integral component of peroxisomal membrane. Part of protein-containing complex. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in heart (RPKM 77.0), thyroid (RPKM 71.6) and 25 other tissues See more Orthologs mouse all