VIP, Official Symbol VIPprovided by HGNC Official Full Name vasoactive intestinal peptideprovided by HGNC Primary source HGNC:HGNC:12693 See related Ensembl:ENSG00000146469 MIM:192320; AllianceGenome:HGNC:12693 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PHM27 Summary The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014] Expression Biased expression in appendix (RPKM 33.5), colon (RPKM 12.6) and 3 other tissues See more Orthologs mouse all