GLS2, Official Symbol GLS2provided by HGNC Official Full Name glutaminase 2provided by HGNC Primary source HGNC:HGNC:29570 See related Ensembl:ENSG00000135423 MIM:606365; AllianceGenome:HGNC:29570 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GA; GLS; LGA; hLGA Summary The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] Expression Biased expression in liver (RPKM 39.1), brain (RPKM 4.2) and 2 other tissues See more Orthologs mouse all