MIF, Official Symbol MIFprovided by HGNC Official Full Name macrophage migration inhibitory factorprovided by HGNC Primary source HGNC:HGNC:7097 See related Ensembl:ENSG00000240972 MIM:153620; AllianceGenome:HGNC:7097 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GIF; GLIF; MMIF Summary This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 164.4), prostate (RPKM 93.1) and 21 other tissues See more Orthologs mouse all