KCNMB3, Official Symbol KCNMB3provided by HGNC Official Full Name potassium calcium-activated channel subfamily M regulatory beta subunit 3provided by HGNC Primary source HGNC:HGNC:6287 See related Ensembl:ENSG00000171121 MIM:605222; AllianceGenome:HGNC:6287 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HBETA3; KCNMB2; KCNMBL; BKBETA3; SLOBETA3; SLO-BETA-3; K(VCA)BETA-3 Summary MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009] Expression Ubiquitous expression in fat (RPKM 6.7), gall bladder (RPKM 6.6) and 25 other tissues See more Orthologs mouse all