LDHA, Official Symbol LDHAprovided by HGNC Official Full Name lactate dehydrogenase Aprovided by HGNC Primary source HGNC:HGNC:6535 See related Ensembl:ENSG00000134333 MIM:150000; AllianceGenome:HGNC:6535 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LDHM; GSD11; PIG19; HEL-S-133P Summary The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008] Expression Ubiquitous expression in small intestine (RPKM 177.1), liver (RPKM 154.8) and 25 other tissues See more Orthologs mouse all