ZIC3, Official Symbol ZIC3provided by HGNC Official Full Name Zic family member 3provided by HGNC Primary source HGNC:HGNC:12874 See related Ensembl:ENSG00000156925 MIM:300265; AllianceGenome:HGNC:12874 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HTX; HTX1; ZNF203; VACTERLX Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all