PTGDR2, Official Symbol PTGDR2provided by HGNC Official Full Name prostaglandin D2 receptor 2provided by HGNC Primary source HGNC:HGNC:4502 See related Ensembl:ENSG00000183134 MIM:604837; AllianceGenome:HGNC:4502 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DP2; DL1R; CD294; CRTH2; GPR44 Summary This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011] Expression Broad expression in stomach (RPKM 4.7), colon (RPKM 3.6) and 21 other tissues See more Orthologs mouse all