CRNN, Official Symbol CRNNprovided by HGNC Official Full Name cornulinprovided by HGNC Primary source HGNC:HGNC:1230 See related Ensembl:ENSG00000143536 MIM:611312; AllianceGenome:HGNC:1230 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DRC1; PDRC1; SEP53; C1orf10 Summary This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq, Jan 2009] Expression Restricted expression toward esophagus (RPKM 2138.4) See more Orthologs mouse all