PXDN, Official Symbol PXDNprovided by HGNC Official Full Name peroxidasinprovided by HGNC Primary source HGNC:HGNC:14966 See related Ensembl:ENSG00000130508 MIM:605158; AllianceGenome:HGNC:14966 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PXN; VPO; MG50; PRG2; ASGD7; COPOA; D2S448; D2S448E; hsPxd01 Summary This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis. [provided by RefSeq, Aug 2014] Expression Broad expression in fat (RPKM 35.5), endometrium (RPKM 27.3) and 21 other tissues See more Orthologs mouse all