CEP250, Official Symbol CEP250provided by HGNC Official Full Name centrosomal protein 250provided by HGNC Primary source HGNC:HGNC:1859 See related Ensembl:ENSG00000126001 MIM:609689; AllianceGenome:HGNC:1859 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CEP2; CNAP1; C-NAP1; CRDHL2 Summary This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in testis (RPKM 6.5), spleen (RPKM 5.2) and 24 other tissues See more Orthologs mouse all