TRPC1, Official Symbol TRPC1provided by HGNC Official Full Name transient receptor potential cation channel subfamily C member 1provided by HGNC Primary source HGNC:HGNC:12333 See related Ensembl:ENSG00000144935 MIM:602343; AllianceGenome:HGNC:12333 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRP1; HTRP-1 Summary The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Expression Ubiquitous expression in ovary (RPKM 4.8), endometrium (RPKM 3.9) and 22 other tissues See more Orthologs mouse all