DENND6B, Official Symbol DENND6Bprovided by HGNC Official Full Name DENN domain containing 6Bprovided by HGNC Primary source HGNC:HGNC:32690 See related Ensembl:ENSG00000205593 AllianceGenome:HGNC:32690 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AFI1B; FAM116B Summary Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. Predicted to be located in cytosol. Predicted to be active in recycling endosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 4.5), testis (RPKM 3.3) and 24 other tissues See more Orthologs mouse all