CAPN8, Official Symbol CAPN8provided by HGNC Official Full Name calpain 8provided by HGNC Primary source HGNC:HGNC:1485 See related Ensembl:ENSG00000203697 MIM:618777; AllianceGenome:HGNC:1485 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as nCL-2 Summary Predicted to enable calcium-dependent cysteine-type endopeptidase activity and identical protein binding activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within calcium-dependent self proteolysis. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Annotation information Note: This gene aligns across a gap in the GRCh38 reference genome assembly, and therefore, the 5' end of this gene was annotated on NT_167186.2 and the 3' end was annotated on NT_004487.20 in NCBI's Homo sapiens Annotation Release 106. [17 Jun 2014] Annotation category: suggests misassembly Expression Biased expression in stomach (RPKM 65.0), lung (RPKM 7.1) and 2 other tissues See more Orthologs mouse all