DYNC1LI1, Official Symbol DYNC1LI1provided by HGNC Official Full Name dynein cytoplasmic 1 light intermediate chain 1provided by HGNC Primary source HGNC:HGNC:18745 See related Ensembl:ENSG00000144635 MIM:615890; AllianceGenome:HGNC:18745 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LIC1; DLC-A; DNCLI1 Summary The protein encoded by this gene belongs to light intermediate subunit family, whose members are components of the multiprotein cytoplasmic dynein complex, which is involved in intracellular trafficking and chromosome segregation during mitosis. The protein plays a role in moving the spindle assembly checkpoint (SAC) from kinetochores to spindle poles. The protein may also mediate binding to other cargo molecules to facilitate intracellular vesicle trafficking. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in testis (RPKM 27.3), heart (RPKM 19.1) and 25 other tissues See more Orthologs mouse all