FBXO31, Official Symbol FBXO31provided by HGNC Official Full Name F-box protein 31provided by HGNC Primary source HGNC:HGNC:16510 See related Ensembl:ENSG00000103264 MIM:609102; AllianceGenome:HGNC:16510 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX14; Fbx31; MRT45; FBXO14; pp2386 Summary This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in fat (RPKM 13.6), ovary (RPKM 7.7) and 25 other tissues See more Orthologs mouse all