REG1A, Official Symbol REG1Aprovided by HGNC Official Full Name regenerating family member 1 alphaprovided by HGNC Primary source HGNC:HGNC:9951 See related Ensembl:ENSG00000115386 MIM:167770; AllianceGenome:HGNC:9951 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P19; PSP; PTP; REG; ICRF; PSPS; PSPS1 Summary This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008] Expression Biased expression in pancreas (RPKM 5037.4), duodenum (RPKM 2788.3) and 2 other tissues See more Orthologs all