KRT78, Official Symbol KRT78provided by HGNC Official Full Name keratin 78provided by HGNC Primary source HGNC:HGNC:28926 See related Ensembl:ENSG00000170423 MIM:611159; AllianceGenome:HGNC:28926 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K5B; K78; Kb40; CK-78 Summary This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified. [provided by RefSeq, Jul 2008] Expression Restricted expression toward esophagus (RPKM 278.9) See more Orthologs all