RGS7BP, Official Symbol RGS7BPprovided by HGNC Official Full Name regulator of G protein signaling 7 binding proteinprovided by HGNC Primary source HGNC:HGNC:23271 See related Ensembl:ENSG00000186479 MIM:610890; AllianceGenome:HGNC:23271 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as R7BP Summary This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between the nucleus and the plasma membrane. The encoded protein could be regulated by reversible palmitoylation, which anchors it to the plasma membrane. Depalmitoylation localizes the protein to the nucleus. Polymorphisms in this gene may be associated with risk of aspirin-exacerbated respiratory disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012] Expression Biased expression in brain (RPKM 14.8), prostate (RPKM 2.8) and 9 other tissues See more Orthologs mouse all