THOC5, Official Symbol THOC5provided by HGNC Official Full Name THO complex subunit 5provided by HGNC Primary source HGNC:HGNC:19074 See related Ensembl:ENSG00000100296 MIM:612733; AllianceGenome:HGNC:19074 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fmip; PK1.3; fSAP79; C22orf19 Summary Predicted to enable mRNA binding activity. Involved in several processes, including monocyte differentiation; negative regulation of DNA damage checkpoint; and viral mRNA export from host cell nucleus. Located in nucleoplasm. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region. Implicated in breast carcinoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 10.3), endometrium (RPKM 6.9) and 25 other tissues See more Orthologs mouse all