CPLX2, Official Symbol CPLX2provided by HGNC Official Full Name complexin 2provided by HGNC Primary source HGNC:HGNC:2310 See related Ensembl:ENSG00000145920 MIM:605033; AllianceGenome:HGNC:2310 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPX2; Hfb1; 921-L; CPX-2 Summary Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 63.0) and adrenal (RPKM 12.1) See more Orthologs mouse all