TRIM46, Official Symbol TRIM46provided by HGNC Official Full Name tripartite motif containing 46provided by HGNC Primary source HGNC:HGNC:19019 See related Ensembl:ENSG00000163462 MIM:600986; AllianceGenome:HGNC:19019 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GENEY; TRIFIC Summary This gene encodes a protein of the tripartite motif (TRIM) family. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. TRIM46 is reported to be involved in the proliferation of multiple types of cancer cells including lung and breast cancer. It has also been shown to control neuronal polarity and axon specification by forming uniform microtubule bundles in the axon. [provided by RefSeq, May 2022] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is locus in the vicinity of disease-associated variant(s). Expression Broad expression in brain (RPKM 2.5), testis (RPKM 0.9) and 14 other tissues See more Orthologs mouse all