CAVIN2, Official Symbol CAVIN2provided by HGNC Official Full Name caveolae associated protein 2provided by HGNC Primary source HGNC:HGNC:10690 See related Ensembl:ENSG00000168497 MIM:606728; AllianceGenome:HGNC:10690 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SDR; SDPR; PS-p68; cavin-2 Summary This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009] Expression Broad expression in fat (RPKM 116.9), lung (RPKM 67.0) and 17 other tissues See more Orthologs mouse all