RNF181, Official Symbol RNF181provided by HGNC Official Full Name ring finger protein 181provided by HGNC Primary source HGNC:HGNC:28037 See related Ensembl:ENSG00000168894 MIM:612490; AllianceGenome:HGNC:28037 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSPC238 Summary RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM, Dec 2008] Expression Ubiquitous expression in kidney (RPKM 21.9), placenta (RPKM 18.7) and 25 other tissues See more Orthologs mouse all