DRAM1, Official Symbol DRAM1provided by HGNC Official Full Name DNA damage regulated autophagy modulator 1provided by HGNC Primary source HGNC:HGNC:25645 See related Ensembl:ENSG00000136048 MIM:610776; AllianceGenome:HGNC:25645 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DRAM Summary This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008] Expression Broad expression in lung (RPKM 41.9), urinary bladder (RPKM 12.1) and 20 other tissues See more Orthologs mouse all