TRPC4AP, Official Symbol TRPC4APprovided by HGNC Official Full Name transient receptor potential cation channel subfamily C member 4 associated proteinprovided by HGNC Primary source HGNC:HGNC:16181 See related Ensembl:ENSG00000100991 MIM:608430; AllianceGenome:HGNC:16181 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TRUSS; TRRP4AP; PPP1R158; C20orf188 Summary Enables phosphatase binding activity and ubiquitin ligase-substrate adaptor activity. Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Part of Cul4A-RING E3 ubiquitin ligase complex. Is active in Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in placenta (RPKM 20.6), spleen (RPKM 19.3) and 25 other tissues See more Orthologs mouse all