FTCD, Official Symbol FTCDprovided by HGNC Official Full Name formimidoyltransferase cyclodeaminaseprovided by HGNC Primary source HGNC:HGNC:3974 See related Ensembl:ENSG00000160282 MIM:606806; AllianceGenome:HGNC:3974 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LCHC1 Summary The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009] Expression Biased expression in liver (RPKM 54.7), kidney (RPKM 35.5) and 1 other tissue See more Orthologs mouse all