S100A3, Official Symbol S100A3provided by HGNC Official Full Name S100 calcium binding protein A3provided by HGNC Primary source HGNC:HGNC:10493 See related Ensembl:ENSG00000188015 MIM:176992; AllianceGenome:HGNC:10493 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as S100E Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008] Expression Biased expression in lung (RPKM 11.5), skin (RPKM 3.7) and 10 other tissues See more Orthologs mouse all