PLK4, Official Symbol PLK4provided by HGNC Official Full Name polo like kinase 4provided by HGNC Primary source HGNC:HGNC:11397 See related Ensembl:ENSG00000142731 MIM:605031; AllianceGenome:HGNC:11397 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAK; STK18; MCCRP2 Summary This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Expression Biased expression in testis (RPKM 12.2), bone marrow (RPKM 8.2) and 12 other tissues See more Orthologs mouse all