LACTB, Official Symbol LACTBprovided by HGNC Official Full Name lactamase betaprovided by HGNC Primary source HGNC:HGNC:16468 See related Ensembl:ENSG00000103642 MIM:608440; AllianceGenome:HGNC:16468 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G24; MRPL56 Summary This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic function. Increased expression of the related mouse gene was found to be associated with obesity. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Dec 2013] Expression Ubiquitous expression in bone marrow (RPKM 9.0), adrenal (RPKM 7.3) and 25 other tissues See more Orthologs mouse all