MTERF1, Official Symbol MTERF1provided by HGNC Official Full Name mitochondrial transcription termination factor 1provided by HGNC Primary source HGNC:HGNC:21463 See related Ensembl:ENSG00000127989 MIM:602318; AllianceGenome:HGNC:21463 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MTERF Summary This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in lymph node (RPKM 5.6), appendix (RPKM 4.0) and 25 other tissues See more Orthologs all