AVPR1A, Official Symbol AVPR1Aprovided by HGNC Official Full Name arginine vasopressin receptor 1Aprovided by HGNC Primary source HGNC:HGNC:895 See related Ensembl:ENSG00000166148 MIM:600821; AllianceGenome:HGNC:895 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as V1aR; AVPR1; AVPR V1a Summary The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008] Expression Biased expression in adrenal (RPKM 29.7), endometrium (RPKM 8.7) and 7 other tissues See more Orthologs mouse all