TRIM28, Official Symbol TRIM28provided by HGNC Official Full Name tripartite motif containing 28provided by HGNC Primary source HGNC:HGNC:16384 See related Ensembl:ENSG00000130726 MIM:601742; AllianceGenome:HGNC:16384 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KAP1; TF1B; RNF96; TIF1B; PPP1R157; TIF1beta Summary The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 89.1), testis (RPKM 80.5) and 25 other tissues See more Orthologs mouse all