FUZ, Official Symbol FUZprovided by HGNC Official Full Name fuzzy planar cell polarity proteinprovided by HGNC Primary source HGNC:HGNC:26219 See related Ensembl:ENSG00000010361 MIM:610622; AllianceGenome:HGNC:26219 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FY; NTD; CPLANE3 Summary This gene encodes a planar cell polarity protein that is involved in ciliogenesis and directional cell movement. Knockout studies in mice exhibit neural tube defects and defective cilia, and mutations in this gene are associated with neural tube defects in humans. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012] Expression Broad expression in testis (RPKM 12.5), kidney (RPKM 6.2) and 25 other tissues See more Orthologs mouse all