INTS11, Official Symbol INTS11provided by HGNC Official Full Name integrator complex subunit 11provided by HGNC Primary source HGNC:HGNC:26052 See related Ensembl:ENSG00000127054 MIM:611354; AllianceGenome:HGNC:26052 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RC68; INT11; PSF3L; RC-68; CPSF3L; CPSF73L; NEDMLOB Summary The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in testis (RPKM 35.0), endometrium (RPKM 21.3) and 25 other tissues See more Orthologs mouse all