COMETT, Official Symbol COMETTprovided by HGNC Official Full Name cytosolic oncogenic antisense to MET transcriptprovided by HGNC Primary source HGNC:HGNC:51196 See related AllianceGenome:HGNC:51196 Gene type ncRNA RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as COMET; LINC01510 Summary This gene encodes a natural antisense transcript highly expressed in papillary thyroid carcinomas harboring BRAF V600E mutation or RET gene rearrangements. This lncRNA induces the downstream MAPK pathway and is part of a co-expression network including different oncogenes belonging to the MAPK and PI3H/AKT pathways. In thyroid carcinomas, this gene has oncogenic properties associated with increased proliferation and drug resistance. [provided by RefSeq, Jan 2020] Expression Restricted expression toward kidney (RPKM 8.2) See more