SYT5, Official Symbol SYT5provided by HGNC Official Full Name synaptotagmin 5provided by HGNC Primary source HGNC:HGNC:11513 See related Ensembl:ENSG00000129990 MIM:600782; AllianceGenome:HGNC:11513 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011] Expression Biased expression in brain (RPKM 20.3) and adrenal (RPKM 2.1) See more Orthologs mouse all