C1QC, Official Symbol C1QCprovided by HGNC Official Full Name complement C1q C chainprovided by HGNC Primary source HGNC:HGNC:1245 See related Ensembl:ENSG00000159189 MIM:120575; AllianceGenome:HGNC:1245 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C1QG; C1Q-C; C1QD3 Summary This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016] Expression Broad expression in spleen (RPKM 519.1), lymph node (RPKM 141.4) and 14 other tissues See more Orthologs mouse all