DYNC2I2, Official Symbol DYNC2I2provided by HGNC Official Full Name dynein 2 intermediate chain 2provided by HGNC Primary source HGNC:HGNC:28296 See related Ensembl:ENSG00000119333 MIM:613363; AllianceGenome:HGNC:28296 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DIC5; WDR34; FAP133; SRTD11; CFAP133; bA216B9.3 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Defects in this gene are a cause of short-rib thoracic dysplasia 11 with or without polydactyly. [provided by RefSeq, Mar 2014] Expression Ubiquitous expression in testis (RPKM 24.0), kidney (RPKM 17.4) and 25 other tissues See more Orthologs mouse all