DSP, Official Symbol DSPprovided by HGNC Official Full Name desmoplakinprovided by HGNC Primary source HGNC:HGNC:3052 See related Ensembl:ENSG00000096696 MIM:125647; AllianceGenome:HGNC:3052 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DP; DCWHKTA Summary This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Biased expression in skin (RPKM 438.1), esophagus (RPKM 191.0) and 7 other tissues See more Orthologs mouse all