TRRAP, Official Symbol TRRAPprovided by HGNC Official Full Name transformation/transcription domain associated proteinprovided by HGNC Primary source HGNC:HGNC:12347 See related Ensembl:ENSG00000196367 MIM:603015; AllianceGenome:HGNC:12347 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Tra1; TR-AP; DEDDFA; DFNA75; PAF400; STAF40; PAF350/400 Summary This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in testis (RPKM 10.2), ovary (RPKM 8.3) and 25 other tissues See more Orthologs mouse all