SDHAF1, Official Symbol SDHAF1provided by HGNC Official Full Name succinate dehydrogenase complex assembly factor 1provided by HGNC Primary source HGNC:HGNC:33867 See related Ensembl:ENSG00000205138 MIM:612848; AllianceGenome:HGNC:33867 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LYRM8; MC2DN2 Summary The succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency).[provided by RefSeq, Mar 2010] Orthologs mouse all