PFN2, Official Symbol PFN2provided by HGNC Official Full Name profilin 2provided by HGNC Primary source HGNC:HGNC:8882 See related Ensembl:ENSG00000070087 MIM:176590; AllianceGenome:HGNC:8882 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PFL; D3S1319E Summary The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 148.4), thyroid (RPKM 50.8) and 19 other tissues See more Orthologs mouse all