CD22, Official Symbol CD22provided by HGNC Official Full Name CD22 moleculeprovided by HGNC Primary source HGNC:HGNC:1643 See related Ensembl:ENSG00000012124 MIM:107266; AllianceGenome:HGNC:1643 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIGLEC2; SIGLEC-2 Summary Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in lymph node (RPKM 101.0), ovary (RPKM 64.7) and 2 other tissues See more Orthologs mouse all