HSPA4, Official Symbol HSPA4provided by HGNC Official Full Name heat shock protein family A (Hsp70) member 4provided by HGNC Primary source HGNC:HGNC:5237 See related Ensembl:ENSG00000170606 MIM:601113; AllianceGenome:HGNC:5237 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RY; APG-2; HSPH2; hsp70; hsp70RY; HEL-S-5a; HS24/P52 Summary Predicted to enable ATP binding activity. Involved in chaperone-mediated protein complex assembly and protein insertion into mitochondrial outer membrane. Located in cytosol and extracellular exosome. Implicated in Chagas disease. Biomarker of chronic obstructive pulmonary disease; rheumatoid arthritis; type 2 diabetes mellitus; and ulcerative colitis. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 45.7), esophagus (RPKM 33.4) and 25 other tissues See more Orthologs mouse all