TSPAN16, Official Symbol TSPAN16provided by HGNC Official Full Name tetraspanin 16provided by HGNC Primary source HGNC:HGNC:30725 See related Ensembl:ENSG00000130167 MIM:617580; AllianceGenome:HGNC:30725 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TM-8; TM4-B; TM4SF16 Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein might couple to signal transduction pathways and possibly modulate cellular activation and adhesion in haemopoietic and neural tissue. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Expression Restricted expression toward testis (RPKM 28.9) See more Orthologs all