EEF1D, Official Symbol EEF1Dprovided by HGNC Official Full Name eukaryotic translation elongation factor 1 deltaprovided by HGNC Primary source HGNC:HGNC:3211 See related Ensembl:ENSG00000104529 MIM:130592; AllianceGenome:HGNC:3211 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EF1D; EF-1D; FP1047 Summary This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010] Expression Ubiquitous expression in ovary (RPKM 42.9), spleen (RPKM 28.8) and 25 other tissues See more Orthologs mouse all