PPP2R5A, Official Symbol PPP2R5Aprovided by HGNC Official Full Name protein phosphatase 2 regulatory subunit B'alphaprovided by HGNC Primary source HGNC:HGNC:9309 See related Ensembl:ENSG00000066027 MIM:601643; AllianceGenome:HGNC:9309 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B56A; PR61A; B56alpha Summary The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in fat (RPKM 41.9), lung (RPKM 33.2) and 25 other tissues See more Orthologs mouse all