OSCAR, Official Symbol OSCARprovided by HGNC Official Full Name osteoclast associated Ig-like receptorprovided by HGNC Primary source HGNC:HGNC:29960 See related Ensembl:ENSG00000170909 MIM:606862; AllianceGenome:HGNC:29960 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PIGR3; PIgR-3 Summary Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013] Expression Biased expression in lung (RPKM 7.4), bone marrow (RPKM 7.3) and 12 other tissues See more Orthologs mouse all