LAGE3, Official Symbol LAGE3provided by HGNC Official Full Name L antigen family member 3provided by HGNC Primary source HGNC:HGNC:26058 See related Ensembl:ENSG00000196976 MIM:300060; AllianceGenome:HGNC:26058 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CVG5; ESO3; Pcc1; ITBA2; GAMOS2; DXS9879E; DXS9951E Summary This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 8.7), adrenal (RPKM 6.8) and 25 other tissues See more Orthologs mouse all