ARHGAP18, Official Symbol ARHGAP18provided by HGNC Official Full Name Rho GTPase activating protein 18provided by HGNC Primary source HGNC:HGNC:21035 See related Ensembl:ENSG00000146376 MIM:613351; AllianceGenome:HGNC:21035 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SENEX; MacGAP; bA307O14.2 Summary Enables GTPase activator activity. Involved in several processes, including regulation of actin filament polymerization; regulation of small GTPase mediated signal transduction; and small GTPase mediated signal transduction. Located in cytosol; nuclear speck; and plasma membrane. Part of cytoplasmic microtubule and ruffle. Implicated in schizophrenia. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in adrenal (RPKM 22.0), lung (RPKM 16.4) and 25 other tissues See more Orthologs mouse all