CPLX1, Official Symbol CPLX1provided by HGNC Official Full Name complexin 1provided by HGNC Primary source HGNC:HGNC:2309 See related Ensembl:ENSG00000168993 MIM:605032; AllianceGenome:HGNC:2309 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPX1; CPX-I; DEE63; EIEE63 Summary Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 19.8), fat (RPKM 3.8) and 5 other tissues See more Orthologs mouse all