ARHGAP21, Official Symbol ARHGAP21provided by HGNC Official Full Name Rho GTPase activating protein 21provided by HGNC Primary source HGNC:HGNC:23725 See related Ensembl:ENSG00000107863 MIM:609870; AllianceGenome:HGNC:23725 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHGAP10 Summary ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in brain (RPKM 26.0), fat (RPKM 12.0) and 25 other tissues See more Orthologs mouse all