ANAPC7, Official Symbol ANAPC7provided by HGNC Official Full Name anaphase promoting complex subunit 7provided by HGNC Primary source HGNC:HGNC:17380 See related Ensembl:ENSG00000196510 MIM:606949; AllianceGenome:HGNC:17380 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APC7; FERBON Summary This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] Expression Ubiquitous expression in testis (RPKM 11.7), esophagus (RPKM 9.0) and 25 other tissues See more Orthologs mouse all