DDX60, Official Symbol DDX60provided by HGNC Official Full Name DExD/H-box helicase 60provided by HGNC Primary source HGNC:HGNC:25942 See related Ensembl:ENSG00000137628 MIM:613974; AllianceGenome:HGNC:25942 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular procsses involving RNA binding and alteration of RNA secondary structure. This gene encodes a DEXD/H box RNA helicase that functions as an antiviral factor and promotes RIG-I-like receptor-mediated signaling. [provided by RefSeq, Apr 2017] Expression Ubiquitous expression in stomach (RPKM 14.0), colon (RPKM 7.7) and 24 other tissues See more Orthologs all