CALCRL, Official Symbol CALCRLprovided by HGNC Official Full Name calcitonin receptor like receptorprovided by HGNC Primary source HGNC:HGNC:16709 See related Ensembl:ENSG00000064989 MIM:114190; AllianceGenome:HGNC:16709 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRLR; CGRPR; LMPHM8 Summary Enables adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Located in endoplasmic reticulum; endosome; and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lung (RPKM 41.7), fat (RPKM 35.2) and 20 other tissues See more Orthologs mouse all