DEFB126, Official Symbol DEFB126provided by HGNC Official Full Name defensin beta 126provided by HGNC Primary source HGNC:HGNC:15900 See related Ensembl:ENSG00000125788 MIM:620131; AllianceGenome:HGNC:15900 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HBD26; DEFB26; hBD-26; C20orf8; DEFB-26; bA530N10.1 Summary Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. The encoded protein is highly similar to an epididymal-specific secretory protein (ESP13.2) from cynomolgus monkey. Mutation of this gene is associated with impaired sperm function. [provided by RefSeq, Nov 2014] Expression Low expression observed in reference dataset See more Orthologs mouse all