SLC46A3, Official Symbol SLC46A3provided by HGNC Official Full Name solute carrier family 46 member 3provided by HGNC Primary source HGNC:HGNC:27501 See related Ensembl:ENSG00000139508 MIM:616764; AllianceGenome:HGNC:27501 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FKSG16 Summary The protein encoded by this gene is a member of a transmembrane protein family that transports small molecules across membranes. The encoded protein has been found in lysosomal membranes, where it can transport catabolites from the lysosomes to the cytoplasm. This protein has been shown to be an effective transporter of the cytotoxic drug maytansine, which is used in antibody-based targeting of cancer cells. [provided by RefSeq, Dec 2016] Expression Broad expression in small intestine (RPKM 41.0), duodenum (RPKM 24.5) and 21 other tissues See more Orthologs mouse all