PACS2, Official Symbol PACS2provided by HGNC Official Full Name phosphofurin acidic cluster sorting protein 2provided by HGNC Primary source HGNC:HGNC:23794 See related Ensembl:ENSG00000179364 MIM:610423; AllianceGenome:HGNC:23794 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEE66; EIEE66; PACS-2; PACS1L Summary Predicted to enable transmembrane transporter binding activity. Involved in endoplasmic reticulum calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and protein localization to plasma membrane. Acts upstream of or within protein localization to phagophore assembly site. Located in endoplasmic reticulum and mitochondrion. Implicated in developmental and epileptic encephalopathy 66. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 15.4), testis (RPKM 10.2) and 25 other tissues See more Orthologs mouse all