CPSF6, Official Symbol CPSF6provided by HGNC Official Full Name cleavage and polyadenylation specific factor 6provided by HGNC Primary source HGNC:HGNC:13871 See related Ensembl:ENSG00000111605 MIM:604979; AllianceGenome:HGNC:13871 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CFIM; CFIM68; CFIM72; HPBRII-4; HPBRII-7 Summary The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 16.3), lymph node (RPKM 15.0) and 25 other tissues See more Orthologs mouse all