TKTL1, Official Symbol TKTL1provided by HGNC Official Full Name transketolase like 1provided by HGNC Primary source HGNC:HGNC:11835 See related Ensembl:ENSG00000007350 MIM:300044; AllianceGenome:HGNC:11835 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TKR; TKT2 Summary The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] Expression Restricted expression toward testis (RPKM 88.4) See more Orthologs mouse all