SULT1A4, Official Symbol SULT1A4provided by HGNC Official Full Name sulfotransferase family 1A member 4provided by HGNC Primary source HGNC:HGNC:30004 See related Ensembl:ENSG00000213648 MIM:615819; AllianceGenome:HGNC:30004 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STM; HAST3; M-PST; ST1A3; ST1A4; TL-PST; ST1A3/ST1A4 Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16, this gene and SULT1A3 arose from a segmental duplication. Read-through transcription exists between this gene and the upstream SLX1B (SLX1 structure-specific endonuclease subunit homolog B) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010] Expression Broad expression in duodenum (RPKM 135.4), small intestine (RPKM 94.3) and 23 other tissues See more Orthologs all