SOAT1, Official Symbol SOAT1provided by HGNC Official Full Name sterol O-acyltransferase 1provided by HGNC Primary source HGNC:HGNC:11177 See related Ensembl:ENSG00000057252 MIM:102642; AllianceGenome:HGNC:11177 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACAT; SOAT; STAT; ACACT; ACAT1; ACAT-1 Summary The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] Annotation information Note: ACAT1 (Gene ID: 38) and SOAT1 (Gene ID: 6646) share the ACAT1 symbol/alias in common. ACAT1 is a widely used alternative name for sterol O-acyltransferase 1 (SOAT1), which can be confused with the official symbol for ACAT1 (acetyl-CoA acetyltransferase 1, GeneID 38). [01 Jun 2018] Expression Broad expression in adrenal (RPKM 68.9), prostate (RPKM 11.4) and 17 other tissues See more Orthologs mouse all