CCT3, Official Symbol CCT3provided by HGNC Official Full Name chaperonin containing TCP1 subunit 3provided by HGNC Primary source HGNC:HGNC:1616 See related Ensembl:ENSG00000163468 MIM:600114; AllianceGenome:HGNC:1616 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCTG; PIG48; TRIC5; CCT-gamma; TCP-1-gamma Summary The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010] Expression Ubiquitous expression in testis (RPKM 72.7), adrenal (RPKM 56.4) and 25 other tissues See more Orthologs mouse all