STK26, Official Symbol STK26provided by HGNC Official Full Name serine/threonine kinase 26provided by HGNC Primary source HGNC:HGNC:18174 See related Ensembl:ENSG00000134602 MIM:300547; AllianceGenome:HGNC:18174 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MASK; MST4 Summary The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] Expression Broad expression in endometrium (RPKM 22.0), bone marrow (RPKM 21.7) and 22 other tissues See more Orthologs mouse all