MAPK4, Official Symbol MAPK4provided by HGNC Official Full Name mitogen-activated protein kinase 4provided by HGNC Primary source HGNC:HGNC:6878 See related Ensembl:ENSG00000141639 MIM:176949; AllianceGenome:HGNC:6878 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ERK4; ERK-4; PRKM4; p63MAPK; p63-MAPK Summary Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Expression Biased expression in adrenal (RPKM 3.2), brain (RPKM 3.1) and 11 other tissues See more Orthologs mouse all