HACD2, Official Symbol HACD2provided by HGNC Official Full Name 3-hydroxyacyl-CoA dehydratase 2provided by HGNC Primary source HGNC:HGNC:9640 See related Ensembl:ENSG00000206527 MIM:615939; AllianceGenome:HGNC:9640 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PTPLB Summary The protein encoded by this gene can catalyze the third step (dehydration) in the conversion of long chain fatty acids to very long chain fatty acids. The encoded protein localizes to the endoplasmic reticulum membrane. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in fat (RPKM 34.0), prostate (RPKM 10.4) and 24 other tissues See more Orthologs mouse all