NEBL, Official Symbol NEBLprovided by HGNC Official Full Name nebuletteprovided by HGNC Primary source HGNC:HGNC:16932 See related Ensembl:ENSG00000078114 MIM:605491; AllianceGenome:HGNC:16932 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LASP2; LNEBL; C10orf113; bA165O3.1 Summary This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] Expression Biased expression in heart (RPKM 103.7), thyroid (RPKM 26.9) and 7 other tissues See more Orthologs mouse all