WNK1, Official Symbol WNK1provided by HGNC Official Full Name WNK lysine deficient protein kinase 1provided by HGNC Primary source HGNC:HGNC:14540 See related Ensembl:ENSG00000060237 MIM:605232; AllianceGenome:HGNC:14540 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KDP; PSK; p65; HSN2; HSAN2; PRKWNK1; PPP1R167 Summary This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010] Expression Ubiquitous expression in kidney (RPKM 30.2), fat (RPKM 24.6) and 25 other tissues See more Orthologs mouse all