VDAC2, Official Symbol VDAC2provided by HGNC Official Full Name voltage dependent anion channel 2provided by HGNC Primary source HGNC:HGNC:12672 See related Ensembl:ENSG00000165637 MIM:193245; AllianceGenome:HGNC:12672 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as POR Summary This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010] Expression Ubiquitous expression in heart (RPKM 81.3), esophagus (RPKM 66.2) and 25 other tissues See more Orthologs mouse all