SPECC1, Official Symbol SPECC1provided by HGNC Official Full Name sperm antigen with calponin homology and coiled-coil domains 1provided by HGNC Primary source HGNC:HGNC:30615 See related Ensembl:ENSG00000128487 MIM:608793; AllianceGenome:HGNC:30615 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NSP; NSP5; CYTSB; HCMOGT1; HCMOGT-1 Summary The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Expression Broad expression in brain (RPKM 6.4), testis (RPKM 6.0) and 23 other tissues See more Orthologs mouse all