SZT2, Official Symbol SZT2provided by HGNC Official Full Name SZT2 subunit of KICSTOR complexprovided by HGNC Primary source HGNC:HGNC:29040 See related Ensembl:ENSG00000198198 MIM:615463; AllianceGenome:HGNC:29040 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DEE18; KICS1; SZT2A; SZT2B; EIEE18; C1orf84; KIAA0467 Summary The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011] Expression Ubiquitous expression in ovary (RPKM 6.6), testis (RPKM 6.5) and 25 other tissues See more Orthologs mouse all