MTCH2, Official Symbol MTCH2provided by HGNC Official Full Name mitochondrial carrier 2provided by HGNC Primary source HGNC:HGNC:17587 See related Ensembl:ENSG00000109919 MIM:613221; AllianceGenome:HGNC:17587 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIMP; HSPC032; SLC25A50 Summary This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons. [provided by RefSeq, Dec 2017] Expression Ubiquitous expression in kidney (RPKM 24.0), testis (RPKM 21.8) and 25 other tissues See more Orthologs mouse all