BMP2K, Official Symbol BMP2Kprovided by HGNC Official Full Name BMP2 inducible kinaseprovided by HGNC Primary source HGNC:HGNC:18041 See related Ensembl:ENSG00000138756 MIM:617648; AllianceGenome:HGNC:18041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BIKE; HRIHFB2017 Summary This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 10.8), lymph node (RPKM 10.8) and 25 other tissues See more Orthologs mouse all