FBXO30, Official Symbol FBXO30provided by HGNC Official Full Name F-box protein 30provided by HGNC Primary source HGNC:HGNC:15600 See related Ensembl:ENSG00000118496 MIM:609101; AllianceGenome:HGNC:15600 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbx30 Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in esophagus (RPKM 3.5), testis (RPKM 3.3) and 25 other tissues See more Orthologs mouse all