HES7, Official Symbol HES7provided by HGNC Official Full Name hes family bHLH transcription factor 7provided by HGNC Primary source HGNC:HGNC:15977 See related Ensembl:ENSG00000179111 MIM:608059; AllianceGenome:HGNC:15977 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCDO4; hHes7; bHLHb37 Summary This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] Expression Low expression observed in reference dataset See more Orthologs mouse all