FBP1, Official Symbol FBP1provided by HGNC Official Full Name fructose-bisphosphatase 1provided by HGNC Primary source HGNC:HGNC:3606 See related Ensembl:ENSG00000165140 MIM:611570; AllianceGenome:HGNC:3606 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBP Summary Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 175.9), kidney (RPKM 118.4) and 9 other tissues See more Orthologs mouse all