FN1, Official Symbol FN1provided by HGNC Official Full Name fibronectin 1provided by HGNC Primary source HGNC:HGNC:3778 See related Ensembl:ENSG00000115414 MIM:135600; AllianceGenome:HGNC:3778 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF Summary This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016] Expression Biased expression in placenta (RPKM 1097.5), liver (RPKM 415.5) and 7 other tissues See more Orthologs mouse all