PRMT7, Official Symbol PRMT7provided by HGNC Official Full Name protein arginine methyltransferase 7provided by HGNC Primary source HGNC:HGNC:25557 See related Ensembl:ENSG00000132600 MIM:610087; AllianceGenome:HGNC:25557 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SBIDDS Summary This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017] Expression Ubiquitous expression in small intestine (RPKM 5.3), testis (RPKM 5.1) and 25 other tissues See more Orthologs mouse all