KIAA0586, Official Symbol KIAA0586provided by HGNC Official Full Name KIAA0586provided by HGNC Primary source HGNC:HGNC:19960 See related Ensembl:ENSG00000100578 MIM:610178; AllianceGenome:HGNC:19960 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JBTS23; SRTD14; Talpid3 Summary This gene encodes a conserved centrosomal protein that functions in ciliogenesis and responds to hedgehog signaling. Mutations in this gene causes Joubert syndrome 23. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Aug 2016] Expression Broad expression in testis (RPKM 10.0), lymph node (RPKM 2.9) and 24 other tissues See more Orthologs mouse all