ASAP1, Official Symbol ASAP1provided by HGNC Official Full Name ArfGAP with SH3 domain, ankyrin repeat and PH domain 1provided by HGNC Primary source HGNC:HGNC:2720 See related Ensembl:ENSG00000153317 MIM:605953; AllianceGenome:HGNC:2720 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAP; PAG2; AMAP1; DDEF1; ZG14P; CENTB4 Summary This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Expression Ubiquitous expression in bone marrow (RPKM 18.3), spleen (RPKM 15.5) and 24 other tissues See more Orthologs mouse all