POLR1A, Official Symbol POLR1Aprovided by HGNC Official Full Name RNA polymerase I subunit Aprovided by HGNC Primary source HGNC:HGNC:17264 See related Ensembl:ENSG00000068654 MIM:616404; AllianceGenome:HGNC:17264 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A190; RPA1; RPO14; AFDCIN; RPA190; RPA194; RPO1-4 Summary The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in this gene are a cause of the Cincinnati type of acrofacial dysostosis. [provided by RefSeq, May 2016] Expression Ubiquitous expression in testis (RPKM 5.9), endometrium (RPKM 5.1) and 25 other tissues See more Orthologs mouse all