CDIPT, Official Symbol CDIPTprovided by HGNC Official Full Name CDP-diacylglycerol--inositol 3-phosphatidyltransferaseprovided by HGNC Primary source HGNC:HGNC:1769 See related Ensembl:ENSG00000103502 MIM:605893; AllianceGenome:HGNC:1769 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PIS; PIS1 Summary Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] Expression Ubiquitous expression in ovary (RPKM 31.5), fat (RPKM 28.7) and 25 other tissues See more Orthologs mouse all