AP1S2, Official Symbol AP1S2provided by HGNC Official Full Name adaptor related protein complex 1 subunit sigma 2provided by HGNC Primary source HGNC:HGNC:560 See related Ensembl:ENSG00000182287 MIM:300629; AllianceGenome:HGNC:560 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGS; DC22; MRX59; MRXS5; MRXSF; MRXS21; SIGMA1B Summary Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013] Expression Ubiquitous expression in heart (RPKM 13.6), endometrium (RPKM 13.6) and 23 other tissues See more Orthologs mouse all