ZWINT, Official Symbol ZWINTprovided by HGNC Official Full Name ZW10 interacting kinetochore proteinprovided by HGNC Primary source HGNC:HGNC:13195 See related Ensembl:ENSG00000122952 MIM:609177; AllianceGenome:HGNC:13195 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIP30; ZWINT1; KNTC2AP; HZwint-1 Summary This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in bone marrow (RPKM 17.2), testis (RPKM 16.4) and 21 other tissues See more Orthologs mouse all