CPNE6, Official Symbol CPNE6provided by HGNC Official Full Name copine 6provided by HGNC Primary source HGNC:HGNC:2319 See related Ensembl:ENSG00000100884 MIM:605688; AllianceGenome:HGNC:2319 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as copine-6 Summary This gene encodes a member of the copine family. Members of this family are calcium-dependent, phospholipid-binding proteins with C2 domains, two calcium- and phospholipid-binding domains. Through their domain structure and lipid binding capabilities, these proteins may play a role in membrane trafficking. This protein is thought to be brain-specific and has a domain structure of two N-terminal C2 domains and one von Willebrand factor A domain. It may have a role in synaptic plasticity. [provided by RefSeq, Jul 2013] Expression Biased expression in brain (RPKM 23.5), small intestine (RPKM 2.5) and 3 other tissues See more Orthologs mouse all