ASCC3, Official Symbol ASCC3provided by HGNC Official Full Name activating signal cointegrator 1 complex subunit 3provided by HGNC Primary source HGNC:HGNC:18697 See related Ensembl:ENSG00000112249 MIM:614217; AllianceGenome:HGNC:18697 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNAH; HELIC1; ASC1p200 Summary This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in urinary bladder (RPKM 5.0), colon (RPKM 4.9) and 25 other tissues See more Orthologs mouse all