IRF2BP1, Official Symbol IRF2BP1provided by HGNC Official Full Name interferon regulatory factor 2 binding protein 1provided by HGNC Primary source HGNC:HGNC:21728 See related Ensembl:ENSG00000170604 MIM:615331; AllianceGenome:HGNC:21728 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables transcription corepressor activity and ubiquitin protein ligase activity. Involved in protein polyubiquitination. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Orthologs mouse all