LEMD2, Official Symbol LEMD2provided by HGNC Official Full Name LEM domain nuclear envelope protein 2provided by HGNC Primary source HGNC:HGNC:21244 See related Ensembl:ENSG00000161904 MIM:616312; AllianceGenome:HGNC:21244 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LEM2; NET25; MARUPS; CTRCT42; dJ482C21.1 Summary This gene encodes a LEM domain-containing transmembrane protein of the inner nuclear membrane. The protein is involved in nuclear structure organization and plays a role in cell signaling and differentiation. Mutations in this gene result in Cataract 46, juvenile-onset. Multiple transcript variants have been found for this gene. [provided by RefSeq, Feb 2017] Expression Ubiquitous expression in testis (RPKM 4.6), spleen (RPKM 4.4) and 25 other tissues See more Orthologs mouse all