ADGRG1, Official Symbol ADGRG1provided by HGNC Official Full Name adhesion G protein-coupled receptor G1provided by HGNC Primary source HGNC:HGNC:4512 See related Ensembl:ENSG00000205336 MIM:604110; AllianceGenome:HGNC:4512 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BFPP; BPPR; GPR56; TM7LN4; TM7XN1 Summary This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] Expression Broad expression in thyroid (RPKM 64.7), brain (RPKM 53.2) and 20 other tissues See more Orthologs mouse all