IQSEC1, Official Symbol IQSEC1provided by HGNC Official Full Name IQ motif and Sec7 domain ArfGEF 1provided by HGNC Primary source HGNC:HGNC:29112 See related Ensembl:ENSG00000144711 MIM:610166; AllianceGenome:HGNC:29112 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BRAG2; GEP100; IDDSSBA; ARFGEP100; ARF-GEP100 Summary Predicted to enable protein kinase binding activity. Predicted to be involved in several processes, including positive regulation of focal adhesion disassembly; positive regulation of keratinocyte migration; and regulation of postsynaptic neurotransmitter receptor internalization. Located in nucleolus. Implicated in intellectual developmental disorder with short stature and behavioral abnormalities. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 17.9), bone marrow (RPKM 13.3) and 25 other tissues See more Orthologs mouse all