FUCA1, Official Symbol FUCA1provided by HGNC Official Full Name alpha-L-fucosidase 1provided by HGNC Primary source HGNC:HGNC:4006 See related Ensembl:ENSG00000179163 MIM:612280; AllianceGenome:HGNC:4006 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FUCA Summary The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.[provided by RefSeq, Oct 2009] Expression Broad expression in lymph node (RPKM 70.6), colon (RPKM 56.5) and 23 other tissues See more Orthologs mouse all