CYP4F22, Official Symbol CYP4F22provided by HGNC Official Full Name cytochrome P450 family 4 subfamily F member 22provided by HGNC Primary source HGNC:HGNC:26820 See related Ensembl:ENSG00000171954 MIM:611495; AllianceGenome:HGNC:26820 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LI3; ARCI5; INLNE Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3. [provided by RefSeq, Jul 2008] Expression Biased expression in skin (RPKM 11.5), esophagus (RPKM 6.1) and 3 other tissues See more Orthologs mouse all