GYS2, Official Symbol GYS2provided by HGNC Official Full Name glycogen synthase 2provided by HGNC Primary source HGNC:HGNC:4707 See related Ensembl:ENSG00000111713 MIM:138571; AllianceGenome:HGNC:4707 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content. [provided by RefSeq, Dec 2009] Expression Restricted expression toward liver (RPKM 35.4) See more Orthologs mouse all