TUBB1, Official Symbol TUBB1provided by HGNC Official Full Name tubulin beta 1 class VIprovided by HGNC Primary source HGNC:HGNC:16257 See related Ensembl:ENSG00000101162 MIM:612901; AllianceGenome:HGNC:16257 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MACTHC1 Summary This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010] Annotation information Note: TUBB1 (Gene ID: 81027) and TUBB (Gene ID: 203068) share the TUBB1 symbol/alias in common. [07 Feb 2019] Expression Biased expression in bone marrow (RPKM 4.6), spleen (RPKM 3.2) and 10 other tissues See more Orthologs mouse all