FERMT3, Official Symbol FERMT3provided by HGNC Official Full Name FERM domain containing kindlin 3provided by HGNC Primary source HGNC:HGNC:23151 See related Ensembl:ENSG00000149781 MIM:607901; AllianceGenome:HGNC:23151 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as URP2; KIND3; MIG-2; MIG2B; URP2SF; UNC112C Summary Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010] Expression Broad expression in bone marrow (RPKM 48.7), spleen (RPKM 38.0) and 15 other tissues See more Orthologs mouse all