ATL1, Official Symbol ATL1provided by HGNC Official Full Name atlastin GTPase 1provided by HGNC Primary source HGNC:HGNC:11231 See related Ensembl:ENSG00000198513 MIM:606439; AllianceGenome:HGNC:11231 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FSP1; GBP3; SPG3; HSN1D; SPG3A; AD-FSP; atlastin1 Summary The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 34.8), endometrium (RPKM 5.1) and 15 other tissues See more Orthologs mouse all