MYCBP, Official Symbol MYCBPprovided by HGNC Official Full Name MYC binding proteinprovided by HGNC Primary source HGNC:HGNC:7554 See related Ensembl:ENSG00000214114 MIM:606535; AllianceGenome:HGNC:7554 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AMY-1 Summary The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011] Expression Ubiquitous expression in testis (RPKM 11.1), colon (RPKM 10.6) and 25 other tissues See more Orthologs mouse all