NLGN4X, Official Symbol NLGN4Xprovided by HGNC Official Full Name neuroligin 4 X-linkedprovided by HGNC Primary source HGNC:HGNC:14287 See related Ensembl:ENSG00000146938 MIM:300427; AllianceGenome:HGNC:14287 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HLNX; HNL4X; NLGN4; ASPGX2; AUTSX2 Summary This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Expression Broad expression in brain (RPKM 6.8), ovary (RPKM 4.3) and 19 other tissues See more Orthologs all