KCNK3, Official Symbol KCNK3provided by HGNC Official Full Name potassium two pore domain channel subfamily K member 3provided by HGNC Primary source HGNC:HGNC:6278 See related Ensembl:ENSG00000171303 MIM:603220; AllianceGenome:HGNC:6278 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OAT1; PPH4; TASK; TASK1; TBAK1; K2p3.1; TASK-1 Summary This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008] Expression Biased expression in adrenal (RPKM 48.3), placenta (RPKM 12.8) and 5 other tissues See more Orthologs mouse all