PRKACB, Official Symbol PRKACBprovided by HGNC Official Full Name protein kinase cAMP-activated catalytic subunit betaprovided by HGNC Primary source HGNC:HGNC:9381 See related Ensembl:ENSG00000142875 MIM:176892; AllianceGenome:HGNC:9381 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAFD2; PKACB; PKA C-beta Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2014] Expression Broad expression in brain (RPKM 61.5), colon (RPKM 21.8) and 22 other tissues See more Orthologs mouse all