DPYS, Official Symbol DPYSprovided by HGNC Official Full Name dihydropyrimidinaseprovided by HGNC Primary source HGNC:HGNC:3013 See related Ensembl:ENSG00000147647 MIM:613326; AllianceGenome:HGNC:3013 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DHP; DHPase Summary Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 34.3) and kidney (RPKM 29.7) See more Orthologs mouse all