TMED7-TICAM2, Official Symbol TMED7-TICAM2provided by HGNC Official Full Name TMED7-TICAM2 readthroughprovided by HGNC Primary source HGNC:HGNC:33945 See related Ensembl:ENSG00000251201 AllianceGenome:HGNC:33945 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIRP; TRAM; TICAM2; TIRAP3; MyD88-4; TICAM-2 Summary This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway. [provided by RefSeq, Nov 2010] Expression Ubiquitous expression in endometrium (RPKM 26.4), prostate (RPKM 21.6) and 25 other tissues See more Orthologs all