DLG3, Official Symbol DLG3provided by HGNC Official Full Name discs large MAGUK scaffold protein 3provided by HGNC Primary source HGNC:HGNC:2902 See related Ensembl:ENSG00000082458 MIM:300189; AllianceGenome:HGNC:2902 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRX; XLMR; MRX90; NEDLG; SAP102; XLID90; PPP1R82 Summary This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] Expression Ubiquitous expression in brain (RPKM 7.8), colon (RPKM 6.2) and 23 other tissues See more Orthologs mouse all