AFAP1L2, Official Symbol AFAP1L2provided by HGNC Official Full Name actin filament associated protein 1 like 2provided by HGNC Primary source HGNC:HGNC:25901 See related Ensembl:ENSG00000169129 MIM:612420; AllianceGenome:HGNC:25901 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as XB130; KIAA1914; CTB-1144G6.4 Summary Enables SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulation of mitotic cell cycle. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in thyroid (RPKM 34.2), spleen (RPKM 23.9) and 15 other tissues See more Orthologs mouse all