GALNT3, Official Symbol GALNT3provided by HGNC Official Full Name polypeptide N-acetylgalactosaminyltransferase 3provided by HGNC Primary source HGNC:HGNC:4125 See related Ensembl:ENSG00000115339 MIM:601756; AllianceGenome:HGNC:4125 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HHS; HFTC; HFTC1; GalNAc-T3 Summary This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities. [provided by RefSeq, Jul 2008] Expression Broad expression in stomach (RPKM 20.1), colon (RPKM 15.8) and 19 other tissues See more Orthologs mouse all