FBXL19, Official Symbol FBXL19provided by HGNC Official Full Name F-box and leucine rich repeat protein 19provided by HGNC Primary source HGNC:HGNC:25300 See related Ensembl:ENSG00000099364 MIM:609085; AllianceGenome:HGNC:25300 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Fbl19; CXXC11; JHDM1C Summary This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Expression Broad expression in testis (RPKM 9.4), brain (RPKM 5.2) and 23 other tissues See more Orthologs mouse all