TTC1, Official Symbol TTC1provided by HGNC Official Full Name tetratricopeptide repeat domain 1provided by HGNC Primary source HGNC:HGNC:12391 See related Ensembl:ENSG00000113312 MIM:601963; AllianceGenome:HGNC:12391 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TPR1 Summary This gene encodes a protein that belongs to the tetratrico peptide repeat superfamily of proteins. The encoded protein plays a role in protein-protein interactions, and binds to the Galpha subunit of G protein-coupled receptors to activate the Ras signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in brain (RPKM 29.2), heart (RPKM 23.5) and 25 other tissues See more Orthologs mouse all