LY6E, Official Symbol LY6Eprovided by HGNC Official Full Name lymphocyte antigen 6 family member Eprovided by HGNC Primary source HGNC:HGNC:6727 See related Ensembl:ENSG00000160932 MIM:601384; AllianceGenome:HGNC:6727 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIGE; SCA2; RIG-E; SCA-2; TSA-1 Summary This gene belongs to the human Ly6 gene family and encodes a glycosylphosphatidyl-inositol (GPI)-anchored cell surface protein. The protein plays an important role in T cell physiology, oncogenesis and immunological regulation. The protein is also involved in modulation of viral infection by coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2. [provided by RefSeq, Aug 2021] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in immune response or antiviral activity. Expression Ubiquitous expression in liver (RPKM 110.6), spleen (RPKM 88.2) and 24 other tissues See more Orthologs mouse all