SATB2, Official Symbol SATB2provided by HGNC Official Full Name SATB homeobox 2provided by HGNC Primary source HGNC:HGNC:21637 See related Ensembl:ENSG00000119042 MIM:608148; AllianceGenome:HGNC:21637 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLSS; DEL2Q32Q33; C2DELq32q33 Summary This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and cognitive disability. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Feb 2010] Expression Biased expression in colon (RPKM 13.7), brain (RPKM 6.3) and 7 other tissues See more Orthologs mouse all