MRPL58, Official Symbol MRPL58provided by HGNC Official Full Name mitochondrial ribosomal protein L58provided by HGNC Primary source HGNC:HGNC:5359 See related Ensembl:ENSG00000167862 MIM:603000; AllianceGenome:HGNC:5359 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DS1; DS-1; ICT1; mL62; MRP-L58 Summary The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in heart (RPKM 10.6), kidney (RPKM 10.3) and 25 other tissues See more Orthologs mouse all