BTLA, Official Symbol BTLAprovided by HGNC Official Full Name B and T lymphocyte associatedprovided by HGNC Primary source HGNC:HGNC:21087 See related Ensembl:ENSG00000186265 MIM:607925; AllianceGenome:HGNC:21087 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BTLA1; CD272 Summary This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011] Expression Biased expression in lymph node (RPKM 5.9), appendix (RPKM 3.2) and 7 other tissues See more Orthologs mouse all