KCNH3, Official Symbol KCNH3provided by HGNC Official Full Name potassium voltage-gated channel subfamily H member 3provided by HGNC Primary source HGNC:HGNC:6252 See related Ensembl:ENSG00000135519 MIM:604527; AllianceGenome:HGNC:6252 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BEC1; ELK2; Kv12.2 Summary The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] Expression Biased expression in brain (RPKM 7.0), testis (RPKM 0.9) and 2 other tissues See more Orthologs mouse all