ALKBH8, Official Symbol ALKBH8provided by HGNC Official Full Name alkB homolog 8, tRNA methyltransferaseprovided by HGNC Primary source HGNC:HGNC:25189 See related Ensembl:ENSG00000137760 MIM:613306; AllianceGenome:HGNC:25189 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ABH8; TRM9; MRT71; TRMT9; TRMT9A Summary Enables tRNA (uracil) methyltransferase activity; tRNA binding activity; and zinc ion binding activity. Involved in cellular response to DNA damage stimulus; tRNA methylation; and tRNA wobble uridine modification. Located in cytosol and nuclear body. Implicated in autosomal recessive non-syndromic intellectual disability. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 3.3), lymph node (RPKM 3.0) and 25 other tissues See more Orthologs mouse all