NACC1, Official Symbol NACC1provided by HGNC Official Full Name nucleus accumbens associated 1provided by HGNC Primary source HGNC:HGNC:20967 See related Ensembl:ENSG00000160877 MIM:610672; AllianceGenome:HGNC:20967 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NAC1; BEND8; NAC-1; NECFM; BTBD30; BTBD14B Summary This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in brain (RPKM 11.6), testis (RPKM 8.4) and 25 other tissues See more Orthologs mouse all