SERGEF, Official Symbol SERGEFprovided by HGNC Official Full Name secretion regulating guanine nucleotide exchange factorprovided by HGNC Primary source HGNC:HGNC:17499 See related Ensembl:ENSG00000129158 MIM:606051; AllianceGenome:HGNC:17499 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Gnefr; DELGEF Summary Predicted to enable guanyl-nucleotide exchange factor activity. Involved in negative regulation of protein secretion. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 11.3), thyroid (RPKM 11.2) and 25 other tissues See more Orthologs mouse all