SIAE, Official Symbol SIAEprovided by HGNC Official Full Name sialic acid acetylesteraseprovided by HGNC Primary source HGNC:HGNC:18187 See related Ensembl:ENSG00000110013 MIM:610079; AllianceGenome:HGNC:18187 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LSE; AIS6; CSEC; YSG2; CSE-C Summary This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011] Expression Broad expression in colon (RPKM 39.1), thyroid (RPKM 19.2) and 21 other tissues See more Orthologs mouse all