THSD7A, Official Symbol THSD7Aprovided by HGNC Official Full Name thrombospondin type 1 domain containing 7Aprovided by HGNC Primary source HGNC:HGNC:22207 See related Ensembl:ENSG00000005108 MIM:612249; AllianceGenome:HGNC:22207 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis. [provided by RefSeq, Aug 2010] Expression Broad expression in kidney (RPKM 4.1), placenta (RPKM 2.1) and 17 other tissues See more Orthologs mouse all