NAT8L, Official Symbol NAT8Lprovided by HGNC Official Full Name N-acetyltransferase 8 likeprovided by HGNC Primary source HGNC:HGNC:26742 See related Ensembl:ENSG00000185818 MIM:610647; AllianceGenome:HGNC:26742 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CML3; NACED; NAT8-LIKE Summary This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010] Expression Biased expression in fat (RPKM 41.3), brain (RPKM 25.5) and 2 other tissues See more Orthologs mouse all