MYH16, Official Symbol MYH16provided by HGNC Official Full Name myosin heavy chain 16 (pseudogene)provided by HGNC Primary source HGNC:HGNC:31038 See related Ensembl:ENSG00000002079 MIM:608580; AllianceGenome:HGNC:31038 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MYH5; MHC20; MYH16P Summary The MYH16 gene, encoding a sarcomeric myosin heavy chain expressed in nonhuman primate masticatory muscles, is inactivated in humans. Stedman et al. (2004) [PubMed 15042088] hypothesized that the decrement in masticatory muscle size caused by the inactivation of MYH16 removed an evolutionary constraint on encephalization in early man.[supplied by OMIM, Mar 2008] Expression Low expression observed in reference dataset See more