NFE2L3, Official Symbol NFE2L3provided by HGNC Official Full Name NFE2 like bZIP transcription factor 3provided by HGNC Primary source HGNC:HGNC:7783 See related Ensembl:ENSG00000050344 MIM:604135; AllianceGenome:HGNC:7783 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NRF3 Summary This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009] Expression Broad expression in placenta (RPKM 30.4), appendix (RPKM 7.6) and 16 other tissues See more Orthologs mouse all