LRRC8C, Official Symbol LRRC8Cprovided by HGNC Official Full Name leucine rich repeat containing 8 VRAC subunit Cprovided by HGNC Primary source HGNC:HGNC:25075 See related Ensembl:ENSG00000171488 MIM:612889; AllianceGenome:HGNC:25075 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AD158; FAD158 Summary Enables volume-sensitive anion channel activity. Involved in cyclic-GMP-AMP transmembrane import across plasma membrane. Located in cytoplasm and plasma membrane. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 7.4), lymph node (RPKM 5.7) and 24 other tissues See more Orthologs mouse all