ADCY8, Official Symbol ADCY8provided by HGNC Official Full Name adenylate cyclase 8provided by HGNC Primary source HGNC:HGNC:239 See related Ensembl:ENSG00000155897 MIM:103070; AllianceGenome:HGNC:239 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AC8; ADCY3; HBAC1 Summary Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 4.1), lung (RPKM 0.8) and 2 other tissues See more Orthologs mouse all