NPB, Official Symbol NPBprovided by HGNC Official Full Name neuropeptide Bprovided by HGNC Primary source HGNC:HGNC:30099 See related Ensembl:ENSG00000183979 MIM:607996; AllianceGenome:HGNC:30099 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as L7; PPL7; PPNPB Summary This gene encodes a member of the neuropeptide B/W family of proteins and preproprotein that is proteolytically processed to generate multiple protein products. The encoded products include neuropeptide B-23 and a C-terminally extended form, neuropeptide B-29, which are characterized by an N-terminal brominated tryptophan amino acid. Both of the encoded peptides bind with higher affinity to neuropeptide B/W (NPB/W) receptor 1 compared to the related NPB/W receptor 2. These peptides may regulate feeding, pain perception, and stress in rodents. [provided by RefSeq, Jul 2015] Expression Biased expression in kidney (RPKM 3.4), fat (RPKM 2.9) and 12 other tissues See more Orthologs mouse all