USP46, Official Symbol USP46provided by HGNC Official Full Name ubiquitin specific peptidase 46provided by HGNC Primary source HGNC:HGNC:20075 See related Ensembl:ENSG00000109189 MIM:612849; AllianceGenome:HGNC:20075 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jun 2009] Expression Ubiquitous expression in brain (RPKM 11.8), heart (RPKM 7.4) and 23 other tissues See more Orthologs mouse all