ATG16L1, Official Symbol ATG16L1provided by HGNC Official Full Name autophagy related 16 like 1provided by HGNC Primary source HGNC:HGNC:21498 See related Ensembl:ENSG00000085978 MIM:610767; AllianceGenome:HGNC:21498 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IBD10; WDR30; APG16L; ATG16A; ATG16L Summary The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010] Expression Ubiquitous expression in bone marrow (RPKM 12.7), testis (RPKM 12.0) and 25 other tissues See more Orthologs mouse all