GOT2, Official Symbol GOT2provided by HGNC Official Full Name glutamic-oxaloacetic transaminase 2provided by HGNC Primary source HGNC:HGNC:4433 See related Ensembl:ENSG00000125166 MIM:138150; AllianceGenome:HGNC:4433 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KAT4; DEE82; KATIV; KYAT4; mitAAT Summary Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] Expression Broad expression in heart (RPKM 129.5), liver (RPKM 91.0) and 24 other tissues See more Orthologs mouse all