ALOX15, Official Symbol ALOX15provided by HGNC Official Full Name arachidonate 15-lipoxygenaseprovided by HGNC Primary source HGNC:HGNC:433 See related Ensembl:ENSG00000161905 MIM:152392; AllianceGenome:HGNC:433 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LOG15; 12-LOX; 15-LOX; 15-LOX-1 Summary This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017] Expression Biased expression in lung (RPKM 5.0), small intestine (RPKM 1.7) and 11 other tissues See more Orthologs all