HCLS1, Official Symbol HCLS1provided by HGNC Official Full Name hematopoietic cell-specific Lyn substrate 1provided by HGNC Primary source HGNC:HGNC:4844 See related Ensembl:ENSG00000180353 MIM:601306; AllianceGenome:HGNC:4844 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HS1; p75; CTTNL; lckBP1 Summary Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of transcription, DNA-templated. Located in cytosol; nucleus; and plasma membrane. Part of transcription regulator complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 118.5), lymph node (RPKM 107.3) and 16 other tissues See more Orthologs mouse all