ARHGEF2, Official Symbol ARHGEF2provided by HGNC Official Full Name Rho/Rac guanine nucleotide exchange factor 2provided by HGNC Primary source HGNC:HGNC:682 See related Ensembl:ENSG00000116584 MIM:607560; AllianceGenome:HGNC:682 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GEF; Lfc; P40; GEFH1; LFP40; GEF-H1; NEDMHM Summary Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009] Expression Ubiquitous expression in lung (RPKM 15.7), spleen (RPKM 12.3) and 24 other tissues See more Orthologs mouse all