TRPV3, Official Symbol TRPV3provided by HGNC Official Full Name transient receptor potential cation channel subfamily V member 3provided by HGNC Primary source HGNC:HGNC:18084 See related Ensembl:ENSG00000167723 MIM:607066; AllianceGenome:HGNC:18084 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OLMS; VRL3; OLMS1; FNEPPK2 Summary This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] Expression Biased expression in skin (RPKM 5.2), small intestine (RPKM 3.6) and 11 other tissues See more Orthologs mouse all