GIGYF2, Official Symbol GIGYF2provided by HGNC Official Full Name GRB10 interacting GYF protein 2provided by HGNC Primary source HGNC:HGNC:11960 See related Ensembl:ENSG00000204120 MIM:612003; AllianceGenome:HGNC:11960 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GYF2; PERQ2; PERQ3; PARK11; TNRC15 Summary This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] Expression Ubiquitous expression in testis (RPKM 16.1), thyroid (RPKM 9.2) and 25 other tissues See more Orthologs mouse all