DTX1, Official Symbol DTX1provided by HGNC Official Full Name deltex E3 ubiquitin ligase 1provided by HGNC Primary source HGNC:HGNC:3060 See related Ensembl:ENSG00000135144 MIM:602582; AllianceGenome:HGNC:3060 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hDx-1; RNF140 Summary Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. [provided by RefSeq, Jul 2008] Expression Broad expression in lymph node (RPKM 13.1), spleen (RPKM 9.7) and 18 other tissues See more Orthologs mouse all