LRRC3B, Official Symbol LRRC3Bprovided by HGNC Official Full Name leucine rich repeat containing 3Bprovided by HGNC Primary source HGNC:HGNC:28105 See related Ensembl:ENSG00000179796 MIM:618996; AllianceGenome:HGNC:28105 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LRP15 Summary The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015] Expression Biased expression in brain (RPKM 1.4), testis (RPKM 0.6) and 3 other tissues See more Orthologs mouse all