BECN1, Official Symbol BECN1provided by HGNC Official Full Name beclin 1provided by HGNC Primary source HGNC:HGNC:1034 See related Ensembl:ENSG00000126581 MIM:604378; AllianceGenome:HGNC:1034 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATG6; VPS30; beclin1 Summary This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] Expression Ubiquitous expression in colon (RPKM 32.3), duodenum (RPKM 27.0) and 25 other tissues See more Orthologs mouse all