HACD1, Official Symbol HACD1provided by HGNC Official Full Name 3-hydroxyacyl-CoA dehydratase 1provided by HGNC Primary source HGNC:HGNC:9639 See related Ensembl:ENSG00000165996 MIM:610467; AllianceGenome:HGNC:9639 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAP; MYONP; PTPLA; CMYP11 Summary The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008] Expression Broad expression in heart (RPKM 20.1), prostate (RPKM 5.4) and 14 other tissues See more Orthologs mouse all