HPR, Official Symbol HPRprovided by HGNC Official Full Name haptoglobin-related proteinprovided by HGNC Primary source HGNC:HGNC:5156 See related Ensembl:ENSG00000261701 MIM:140210; AllianceGenome:HGNC:5156 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HP; A-259H10.2 Summary This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011] Expression Restricted expression toward liver (RPKM 3276.0) See more Orthologs all