PLXNC1, Official Symbol PLXNC1provided by HGNC Official Full Name plexin C1provided by HGNC Primary source HGNC:HGNC:9106 See related Ensembl:ENSG00000136040 MIM:604259; AllianceGenome:HGNC:9106 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CD232; VESPR; PLXN-C1 Summary This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011] Expression Broad expression in appendix (RPKM 8.1), testis (RPKM 6.6) and 23 other tissues See more Orthologs mouse all