KLHDC2, Official Symbol KLHDC2provided by HGNC Official Full Name kelch domain containing 2provided by HGNC Primary source HGNC:HGNC:20231 See related Ensembl:ENSG00000165516 MIM:611280; AllianceGenome:HGNC:20231 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LCP; HCLP1; HCLP-1 Summary Enables ubiquitin ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in nuclear body and nuclear membrane. Is active in Cul2-RING ubiquitin ligase complex and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 22.9), kidney (RPKM 22.5) and 25 other tissues See more Orthologs mouse all