CUL7, Official Symbol CUL7provided by HGNC Official Full Name cullin 7provided by HGNC Primary source HGNC:HGNC:21024 See related Ensembl:ENSG00000044090 MIM:609577; AllianceGenome:HGNC:21024 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 3M1; CUL-7; KIAA0076; dJ20C7.5 Summary The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] Expression Ubiquitous expression in ovary (RPKM 10.5), thyroid (RPKM 8.9) and 25 other tissues See more Orthologs mouse all