WDR49, Official Symbol WDR49provided by HGNC Official Full Name WD repeat domain 49provided by HGNC Primary source HGNC:HGNC:26587 See related Ensembl:ENSG00000174776 AllianceGenome:HGNC:26587 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the WD repeat protein family with nine WD repeats. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] Expression Biased expression in brain (RPKM 1.0), small intestine (RPKM 1.0) and 13 other tissues See more Orthologs mouse all