PPRC1, Official Symbol PPRC1provided by HGNC Official Full Name PPARG related coactivator 1provided by HGNC Primary source HGNC:HGNC:30025 See related Ensembl:ENSG00000148840 MIM:617462; AllianceGenome:HGNC:30025 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRC Summary The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] Expression Ubiquitous expression in gall bladder (RPKM 7.9), appendix (RPKM 7.5) and 25 other tissues See more Orthologs mouse all