LYPLA1, Official Symbol LYPLA1provided by HGNC Official Full Name lysophospholipase 1provided by HGNC Primary source HGNC:HGNC:6737 See related Ensembl:ENSG00000120992 MIM:605599; AllianceGenome:HGNC:6737 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APT1; LPL1; APT-1; LPL-I; hAPT1 Summary This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013] Expression Ubiquitous expression in urinary bladder (RPKM 38.7), testis (RPKM 35.4) and 25 other tissues See more Orthologs mouse all