KLF2, Official Symbol KLF2provided by HGNC Official Full Name KLF transcription factor 2provided by HGNC Primary source HGNC:HGNC:6347 See related Ensembl:ENSG00000127528 MIM:602016; AllianceGenome:HGNC:6347 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LKLF Summary This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is expressed early in mammalian development and is found in many different cell types. The protein acts to bind the CACCC box found in the promoter of target genes to activate their transcription. It plays a role in many processes during development and disease including adipogenesis, embryonic erythropoiesis, epithelial integrity, inflammation and t-cell viability. [provided by RefSeq, Mar 2017] Expression Broad expression in fat (RPKM 40.2), ovary (RPKM 23.1) and 19 other tissues See more Orthologs mouse all