LIMS2, Official Symbol LIMS2provided by HGNC Official Full Name LIM zinc finger domain containing 2provided by HGNC Primary source HGNC:HGNC:16084 See related Ensembl:ENSG00000072163 MIM:607908; AllianceGenome:HGNC:16084 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LGMD2W; PINCH2; MDRCMTT; PINCH-2 Summary This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Expression Broad expression in endometrium (RPKM 24.9), fat (RPKM 20.9) and 23 other tissues See more Orthologs mouse all