SNAI2, Official Symbol SNAI2provided by HGNC Official Full Name snail family transcriptional repressor 2provided by HGNC Primary source HGNC:HGNC:11094 See related Ensembl:ENSG00000019549 MIM:602150; AllianceGenome:HGNC:11094 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SLUG; WS2D; SLUGH; SLUGH1; SNAIL2 Summary This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in endometrium (RPKM 22.8), ovary (RPKM 21.9) and 22 other tissues See more Orthologs mouse all