RILP, Official Symbol RILPprovided by HGNC Official Full Name Rab interacting lysosomal proteinprovided by HGNC Primary source HGNC:HGNC:30266 See related Ensembl:ENSG00000167705 MIM:607848; AllianceGenome:HGNC:30266 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP10141 Summary This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in fat (RPKM 11.4), duodenum (RPKM 8.5) and 25 other tissues See more Orthologs mouse all