ENPP3, Official Symbol ENPP3provided by HGNC Official Full Name ectonucleotide pyrophosphatase/phosphodiesterase 3provided by HGNC Primary source HGNC:HGNC:3358 See related Ensembl:ENSG00000154269 MIM:602182; AllianceGenome:HGNC:3358 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B10; NPP3; PDNP3; CD203c; PD-IBETA Summary The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Oct 2015] Expression Biased expression in small intestine (RPKM 19.6), duodenum (RPKM 6.7) and 6 other tissues See more Orthologs mouse all