AMTN, Official Symbol AMTNprovided by HGNC Official Full Name amelotinprovided by HGNC Primary source HGNC:HGNC:33188 See related Ensembl:ENSG00000187689 MIM:610912; AllianceGenome:HGNC:33188 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AI3B; UNQ689 Summary The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM, Mar 2008] Expression Biased expression in stomach (RPKM 3.1), prostate (RPKM 1.0) and 1 other tissue See more Orthologs mouse all