SLMAP, Official Symbol SLMAPprovided by HGNC Official Full Name sarcolemma associated proteinprovided by HGNC Primary source HGNC:HGNC:16643 See related Ensembl:ENSG00000163681 MIM:602701; AllianceGenome:HGNC:16643 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SLAP Summary This gene encodes a component of a conserved striatin-interacting phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] Expression Ubiquitous expression in heart (RPKM 29.5), esophagus (RPKM 29.0) and 24 other tissues See more Orthologs mouse all