IGFBP6, Official Symbol IGFBP6provided by HGNC Official Full Name insulin like growth factor binding protein 6provided by HGNC Primary source HGNC:HGNC:5475 See related Ensembl:ENSG00000167779 MIM:146735; AllianceGenome:HGNC:5475 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IBP6 Summary Enables identical protein binding activity and insulin-like growth factor II binding activity. Involved in cell migration and positive regulation of stress-activated MAPK cascade. Part of insulin-like growth factor binary complex. Implicated in obesity. Biomarker of breast cancer; in situ carcinoma; leiomyoma; and neovascular inflammatory vitreoretinopathy. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in fat (RPKM 60.7), prostate (RPKM 49.9) and 17 other tissues See more Orthologs mouse all