PRKCD, Official Symbol PRKCDprovided by HGNC Official Full Name protein kinase C deltaprovided by HGNC Primary source HGNC:HGNC:9399 See related Ensembl:ENSG00000163932 MIM:176977; AllianceGenome:HGNC:9399 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MAY1; PKCD; ALPS3; CVID9; nPKC-delta Summary The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome. [provided by RefSeq, Aug 2017] Expression Ubiquitous expression in adrenal (RPKM 23.1), bone marrow (RPKM 21.7) and 25 other tissues See more Orthologs mouse all