MMRN1, Official Symbol MMRN1provided by HGNC Official Full Name multimerin 1provided by HGNC Primary source HGNC:HGNC:7178 See related Ensembl:ENSG00000138722 MIM:601456; AllianceGenome:HGNC:7178 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ECM; MMRN; GPIa*; EMILIN4 Summary Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008] Expression Broad expression in placenta (RPKM 19.8), gall bladder (RPKM 14.4) and 19 other tissues See more Orthologs mouse all