THOC3, Official Symbol THOC3provided by HGNC Official Full Name THO complex subunit 3provided by HGNC Primary source HGNC:HGNC:19072 See related Ensembl:ENSG00000051596 MIM:606929; AllianceGenome:HGNC:19072 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as THO3; hTREX45 Summary This gene encodes a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export complex is recruited to the 5'-end of messenger RNAs in a splicing- and cap-dependent manner. Studies of a related complex in mouse suggest that the metazoan transcription export complex is involved in cell differentiation and development. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, May 2013] Expression Ubiquitous expression in esophagus (RPKM 29.0), testis (RPKM 21.2) and 24 other tissues See more Orthologs mouse all