SEMA4D, Official Symbol SEMA4Dprovided by HGNC Official Full Name semaphorin 4Dprovided by HGNC Primary source HGNC:HGNC:10732 See related Ensembl:ENSG00000187764 MIM:601866; AllianceGenome:HGNC:10732 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A8; GR3; BB18; CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G Summary Enables identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase signaling; regulation of neuron projection development; and regulation of phosphate metabolic process. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lymph node (RPKM 12.0), appendix (RPKM 8.6) and 22 other tissues See more Orthologs mouse all