TIMM44, Official Symbol TIMM44provided by HGNC Official Full Name translocase of inner mitochondrial membrane 44provided by HGNC Primary source HGNC:HGNC:17316 See related Ensembl:ENSG00000104980 MIM:605058; AllianceGenome:HGNC:17316 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIM44 Summary This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in heart (RPKM 13.8), thyroid (RPKM 10.9) and 25 other tissues See more Orthologs mouse all