DPP8, Official Symbol DPP8provided by HGNC Official Full Name dipeptidyl peptidase 8provided by HGNC Primary source HGNC:HGNC:16490 See related Ensembl:ENSG00000074603 MIM:606819; AllianceGenome:HGNC:16490 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DP8; DPRP1; DPRP-1; MST097; MSTP097; MSTP135; MSTP141 Summary This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 9.5), testis (RPKM 9.3) and 25 other tissues See more Orthologs mouse all