UBE2N, Official Symbol UBE2Nprovided by HGNC Official Full Name ubiquitin conjugating enzyme E2 Nprovided by HGNC Primary source HGNC:HGNC:12492 See related Ensembl:ENSG00000177889 MIM:603679; AllianceGenome:HGNC:12492 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBC13; UbcH13; UBCHBEN; HEL-S-71; UbcH-ben; UBCHBEN; UBC13 Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 18.8), brain (RPKM 12.2) and 25 other tissues See more Orthologs mouse all