PLA2G2D, Official Symbol PLA2G2Dprovided by HGNC Official Full Name phospholipase A2 group IIDprovided by HGNC Primary source HGNC:HGNC:9033 See related Ensembl:ENSG00000117215 MIM:605630; AllianceGenome:HGNC:9033 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPLASH; sPLA2S; PLA2IID; sPLA2-IID Summary This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] Expression Biased expression in lymph node (RPKM 63.3), appendix (RPKM 10.7) and 2 other tissues See more Orthologs all