SHOC2, Official Symbol SHOC2provided by HGNC Official Full Name SHOC2 leucine rich repeat scaffold proteinprovided by HGNC Primary source HGNC:HGNC:15454 See related Ensembl:ENSG00000108061 MIM:602775; AllianceGenome:HGNC:15454 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SOC2; SUR8; NSLH1; SIAA0862 Summary This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair. [provided by RefSeq, May 2010] Expression Ubiquitous expression in testis (RPKM 10.0), bone marrow (RPKM 7.4) and 25 other tissues See more Orthologs mouse all