MDGA1, Official Symbol MDGA1provided by HGNC Official Full Name MAM domain containing glycosylphosphatidylinositol anchor 1provided by HGNC Primary source HGNC:HGNC:19267 See related Ensembl:ENSG00000112139 MIM:609626; AllianceGenome:HGNC:19267 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPIM; MAMDC3 Summary This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six Ig-like domains, a single fibronectin type III domain, a MAM domain and a C-terminal GPI-anchoring site. Studies in other mammals suggest this protein plays a role in cell adhesion, migration, and axon guidance and, in the developing brain, neuronal migration. In humans, this gene is associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2016] Expression Broad expression in brain (RPKM 2.6), ovary (RPKM 2.3) and 21 other tissues See more Orthologs mouse all