USP13, Official Symbol USP13provided by HGNC Official Full Name ubiquitin specific peptidase 13provided by HGNC Primary source HGNC:HGNC:12611 See related Ensembl:ENSG00000058056 MIM:603591; AllianceGenome:HGNC:12611 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ISOT3; IsoT-3 Summary Enables several functions, including BAT3 complex binding activity; chaperone binding activity; and cysteine-type peptidase activity. Involved in several processes, including maintenance of unfolded protein involved in ERAD pathway; regulation of cellular catabolic process; and regulation of transcription, DNA-templated. Acts upstream of or within protein deubiquitination and protein stabilization. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in heart (RPKM 16.6), adrenal (RPKM 7.5) and 21 other tissues See more Orthologs mouse all