NKX6-1, Official Symbol NKX6-1provided by HGNC Official Full Name NK6 homeobox 1provided by HGNC Primary source HGNC:HGNC:7839 See related Ensembl:ENSG00000163623 MIM:602563; AllianceGenome:HGNC:7839 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NKX6A; NKX6.1 Summary In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008] Expression Biased expression in esophagus (RPKM 3.3), thyroid (RPKM 0.9) and 4 other tissues See more Orthologs mouse all