MYBL2, Official Symbol MYBL2provided by HGNC Official Full Name MYB proto-oncogene like 2provided by HGNC Primary source HGNC:HGNC:7548 See related Ensembl:ENSG00000101057 MIM:601415; AllianceGenome:HGNC:7548 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BMYB; B-MYB Summary The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] Expression Biased expression in bone marrow (RPKM 29.8), lymph node (RPKM 25.5) and 11 other tissues See more Orthologs mouse all