NETO2, Official Symbol NETO2provided by HGNC Official Full Name neuropilin and tolloid like 2provided by HGNC Primary source HGNC:HGNC:14644 See related Ensembl:ENSG00000171208 MIM:607974; AllianceGenome:HGNC:14644 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BTCL2; NEOT2 Summary This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] Expression Broad expression in spleen (RPKM 8.8), brain (RPKM 6.7) and 17 other tissues See more Orthologs mouse all