NDUFAF6, Official Symbol NDUFAF6provided by HGNC Official Full Name NADH:ubiquinone oxidoreductase complex assembly factor 6provided by HGNC Primary source HGNC:HGNC:28625 See related Ensembl:ENSG00000156170 MIM:612392; AllianceGenome:HGNC:28625 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FRTS5; C8orf38; MC1DN17 Summary This gene encodes a protein that localizes to mitochondria and contains a predicted phytoene synthase domain. The encoded protein plays an important role in the assembly of complex I (NADH-ubiquinone oxidoreductase) of the mitochondrial respiratory chain through regulation of subunit ND1 biogenesis. Mutations in this gene are associated with complex I enzymatic deficiency. [provided by RefSeq, Nov 2011] Expression Ubiquitous expression in thyroid (RPKM 1.4), testis (RPKM 1.4) and 25 other tissues See more Orthologs mouse all