STEAP3, Official Symbol STEAP3provided by HGNC Official Full Name STEAP3 metalloreductaseprovided by HGNC Primary source HGNC:HGNC:24592 See related Ensembl:ENSG00000115107 MIM:609671; AllianceGenome:HGNC:24592 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STMP3; TSAP6; pHyde; AHMIO2; dudlin-2; dudulin-2 Summary This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] Expression Ubiquitous expression in liver (RPKM 27.2), duodenum (RPKM 11.9) and 23 other tissues See more Orthologs mouse all