SAFB2, Official Symbol SAFB2provided by HGNC Official Full Name scaffold attachment factor B2provided by HGNC Primary source HGNC:HGNC:21605 See related Ensembl:ENSG00000130254 MIM:608066; AllianceGenome:HGNC:21605 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016] Expression Ubiquitous expression in kidney (RPKM 19.8), spleen (RPKM 18.1) and 25 other tissues See more Orthologs mouse all