GABBR1, Official Symbol GABBR1provided by HGNC Official Full Name gamma-aminobutyric acid type B receptor subunit 1provided by HGNC Primary source HGNC:HGNC:4070 See related Ensembl:ENSG00000204681 MIM:603540; AllianceGenome:HGNC:4070 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GB1; GPRC3A; GABABR1; GABBR1-3 Summary This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016] Expression Broad expression in brain (RPKM 72.0), spleen (RPKM 14.7) and 15 other tissues See more Orthologs mouse all