GYPC, Official Symbol GYPCprovided by HGNC Official Full Name glycophorin C (Gerbich blood group)provided by HGNC Primary source HGNC:HGNC:4704 See related Ensembl:ENSG00000136732 MIM:110750; AllianceGenome:HGNC:4704 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2' Summary Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012] Expression Broad expression in bone marrow (RPKM 63.1), fat (RPKM 47.2) and 17 other tissues See more Orthologs mouse all