MIP, Official Symbol MIPprovided by HGNC Official Full Name major intrinsic protein of lens fiberprovided by HGNC Primary source HGNC:HGNC:7103 See related Ensembl:ENSG00000135517 MIM:154050; AllianceGenome:HGNC:7103 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AQP0; LIM1; MP26; MIP26; CTRCT15 Summary Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13. [provided by RefSeq, Jul 2008] Expression Low expression observed in reference dataset See more Orthologs mouse all