FMO2, Official Symbol FMO2provided by HGNC Official Full Name flavin containing dimethylaniline monoxygenase 2provided by HGNC Primary source HGNC:HGNC:3770 See related Ensembl:ENSG00000094963 MIM:603955; AllianceGenome:HGNC:3770 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FMO1B1 Summary This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] Expression Biased expression in fat (RPKM 59.7), lung (RPKM 58.7) and 8 other tissues See more Orthologs mouse all