POLE3, Official Symbol POLE3provided by HGNC Official Full Name DNA polymerase epsilon 3, accessory subunitprovided by HGNC Primary source HGNC:HGNC:13546 See related Ensembl:ENSG00000148229 MIM:607267; AllianceGenome:HGNC:13546 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p17; YBL1; CHRAC2; CHRAC17; CHARAC17 Summary POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004] Expression Ubiquitous expression in bone marrow (RPKM 36.1), testis (RPKM 24.6) and 25 other tissues See more Orthologs mouse all