DLG4, Official Symbol DLG4provided by HGNC Official Full Name discs large MAGUK scaffold protein 4provided by HGNC Primary source HGNC:HGNC:2903 See related Ensembl:ENSG00000132535 MIM:602887; AllianceGenome:HGNC:2903 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRD62; PSD95; SAP90; SAP-90 Summary This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in brain (RPKM 34.6), testis (RPKM 6.2) and 17 other tissues See more Orthologs mouse all