INTS6, Official Symbol INTS6provided by HGNC Official Full Name integrator complex subunit 6provided by HGNC Primary source HGNC:HGNC:14879 See related Ensembl:ENSG00000102786 MIM:604331; AllianceGenome:HGNC:14879 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HDB; INT6; DBI-1; DDX26; DICE1; DDX26A; Notchl2 Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015] Expression Broad expression in testis (RPKM 13.0), thyroid (RPKM 3.7) and 25 other tissues See more Orthologs mouse all