KNSTRN, Official Symbol KNSTRNprovided by HGNC Official Full Name kinetochore localized astrin (SPAG5) binding proteinprovided by HGNC Primary source HGNC:HGNC:30767 See related Ensembl:ENSG00000128944 MIM:614718; AllianceGenome:HGNC:30767 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SKAP; HSD11; ROCHIS; C15orf23; TRAF4AF1 Summary Enables microtubule plus-end binding activity and protein homodimerization activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; mitotic sister chromatid segregation; and regulation of attachment of spindle microtubules to kinetochore. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and ruffle. Implicated in actinic keratosis and skin squamous cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 31.0), thyroid (RPKM 17.6) and 23 other tissues See more Orthologs mouse all