CTSW, Official Symbol CTSWprovided by HGNC Official Full Name cathepsin Wprovided by HGNC Primary source HGNC:HGNC:2546 See related Ensembl:ENSG00000172543 MIM:602364; AllianceGenome:HGNC:2546 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LYPN Summary The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 42.0), spleen (RPKM 24.6) and 12 other tissues See more Orthologs mouse all