KLB, Official Symbol KLBprovided by HGNC Official Full Name klotho betaprovided by HGNC Primary source HGNC:HGNC:15527 See related Ensembl:ENSG00000134962 MIM:611135; AllianceGenome:HGNC:15527 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BKL Summary Enables fibroblast growth factor binding activity and fibroblast growth factor receptor binding activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway. Predicted to act upstream of or within positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway and positive regulation of cell population proliferation. Predicted to be located in plasma membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in fat (RPKM 16.3), liver (RPKM 5.1) and 2 other tissues See more Orthologs mouse all