MACF1, Official Symbol MACF1provided by HGNC Official Full Name microtubule actin crosslinking factor 1provided by HGNC Primary source HGNC:HGNC:13664 See related Ensembl:ENSG00000127603 MIM:608271; AllianceGenome:HGNC:13664 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACF7; LIS9; MACF; OFC4; ABP620; KIAA0754; Lnc-PMIF Summary This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013] Expression Ubiquitous expression in lung (RPKM 17.3), ovary (RPKM 13.9) and 25 other tissues See more Orthologs mouse all