CEBPE, Official Symbol CEBPEprovided by HGNC Official Full Name CCAAT enhancer binding protein epsilonprovided by HGNC Primary source HGNC:HGNC:1836 See related Ensembl:ENSG00000092067 MIM:600749; AllianceGenome:HGNC:1836 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRP1; SGD1; IMD108; C/EBP-epsilon; c/EBP epsilon Summary The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 14.1) and small intestine (RPKM 1.0) See more Orthologs mouse all