MARK2, Official Symbol MARK2provided by HGNC Official Full Name microtubule affinity regulating kinase 2provided by HGNC Primary source HGNC:HGNC:3332 See related Ensembl:ENSG00000072518 MIM:600526; AllianceGenome:HGNC:3332 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EMK1; EMK-1; PAR-1; Par1b; Par-1b Summary This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] Expression Ubiquitous expression in esophagus (RPKM 11.9), colon (RPKM 10.6) and 25 other tissues See more Orthologs mouse all