IL1RAP, Official Symbol IL1RAPprovided by HGNC Official Full Name interleukin 1 receptor accessory proteinprovided by HGNC Primary source HGNC:HGNC:5995 See related Ensembl:ENSG00000196083 MIM:602626; AllianceGenome:HGNC:5995 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IL1R3; C3orf13; IL-1RAcP Summary This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018] Expression Broad expression in liver (RPKM 11.2), placenta (RPKM 7.8) and 21 other tissues See more Orthologs mouse all