BIK, Official Symbol BIKprovided by HGNC Official Full Name BCL2 interacting killerprovided by HGNC Primary source HGNC:HGNC:1051 See related Ensembl:ENSG00000100290 MIM:603392; AllianceGenome:HGNC:1051 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BP4; NBK; BIP1 Summary The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011] Expression Biased expression in stomach (RPKM 6.4), colon (RPKM 5.6) and 13 other tissues See more Orthologs mouse all