POLE4, Official Symbol POLE4provided by HGNC Official Full Name DNA polymerase epsilon 4, accessory subunitprovided by HGNC Primary source HGNC:HGNC:18755 See related Ensembl:ENSG00000115350 MIM:607269; AllianceGenome:HGNC:18755 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p12; YHHQ1 Summary POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004] Expression Ubiquitous expression in fat (RPKM 27.9), bone marrow (RPKM 20.0) and 25 other tissues See more Orthologs mouse all