BTBD1, Official Symbol BTBD1provided by HGNC Official Full Name BTB domain containing 1provided by HGNC Primary source HGNC:HGNC:1120 See related Ensembl:ENSG00000064726 MIM:608530; AllianceGenome:HGNC:1120 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C15orf1; NS5ATP8 Summary The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 40.3), testis (RPKM 36.9) and 25 other tissues See more Orthologs mouse all