KCNJ5, Official Symbol KCNJ5provided by HGNC Official Full Name potassium inwardly rectifying channel subfamily J member 5provided by HGNC Primary source HGNC:HGNC:6266 See related Ensembl:ENSG00000120457 MIM:600734; AllianceGenome:HGNC:6266 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CIR; GIRK4; KATP1; LQT13; KIR3.4 Summary This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017] Expression Biased expression in adrenal (RPKM 34.9), spleen (RPKM 8.6) and 4 other tissues See more Orthologs mouse all