SHARPIN, Official Symbol SHARPINprovided by HGNC Official Full Name SHANK associated RH domain interactorprovided by HGNC Primary source HGNC:HGNC:25321 See related Ensembl:ENSG00000179526 MIM:611885; AllianceGenome:HGNC:25321 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SIPL1 Summary Enables polyubiquitin modification-dependent protein binding activity. Involved in protein linear polyubiquitination and regulation of signal transduction. Located in cytosol. Part of LUBAC complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 39.8), fat (RPKM 13.6) and 25 other tissues See more Orthologs mouse all