RAP1GAP2, Official Symbol RAP1GAP2provided by HGNC Official Full Name RAP1 GTPase activating protein 2provided by HGNC Primary source HGNC:HGNC:29176 See related Ensembl:ENSG00000132359 MIM:618714; AllianceGenome:HGNC:29176 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GARNL4; RAP1GA3 Summary This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Expression Ubiquitous expression in brain (RPKM 11.5), bone marrow (RPKM 10.7) and 24 other tissues See more Orthologs mouse all