FAR2, Official Symbol FAR2provided by HGNC Official Full Name fatty acyl-CoA reductase 2provided by HGNC Primary source HGNC:HGNC:25531 See related Ensembl:ENSG00000064763 MIM:616156; AllianceGenome:HGNC:25531 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MLSTD1; SDR10E2; HEL-S-81 Summary This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. [provided by RefSeq, Nov 2012] Expression Broad expression in colon (RPKM 8.7), small intestine (RPKM 5.0) and 22 other tissues See more Orthologs mouse all