APOBEC3H, Official Symbol APOBEC3Hprovided by HGNC Official Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 3Hprovided by HGNC Primary source HGNC:HGNC:24100 See related Ensembl:ENSG00000100298 MIM:610976; AllianceGenome:HGNC:24100 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as A3H; ARP10; ARP-10 Summary This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] Expression Broad expression in lymph node (RPKM 1.2), colon (RPKM 1.0) and 22 other tissues See more Orthologs mouse all