SEPTIN6, Official Symbol SEPTIN6provided by HGNC Official Full Name septin 6provided by HGNC Primary source HGNC:HGNC:15848 See related Ensembl:ENSG00000125354 MIM:300683; AllianceGenome:HGNC:15848 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SEP2; SEPT2; SEPT6 Summary This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008] Expression Broad expression in lymph node (RPKM 36.8), adrenal (RPKM 23.4) and 23 other tissues See more Orthologs mouse all