NKX6-2, Official Symbol NKX6-2provided by HGNC Official Full Name NK6 homeobox 2provided by HGNC Primary source HGNC:HGNC:19321 See related Ensembl:ENSG00000148826 MIM:605955; AllianceGenome:HGNC:19321 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GTX; NKX6B; SPAX8; NKX6.2 Summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in cell differentiation; regulation of myelination; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; neurogenesis; and neuromuscular process controlling balance. Predicted to be part of chromatin. Predicted to be active in nucleus. Implicated in spastic ataxia 8. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in stomach (RPKM 17.5), brain (RPKM 14.0) and 25 other tissues See more Orthologs mouse all