MYL2, Official Symbol MYL2provided by HGNC Official Full Name myosin light chain 2provided by HGNC Primary source HGNC:HGNC:7583 See related Ensembl:ENSG00000111245 MIM:160781; AllianceGenome:HGNC:7583 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MLC2; CMH10; MFM12; MLC-2; MLC-2v; MLC-2s/v Summary This gene encodes a major sarcomeric protein in mammalian striated muscle. The encoded protein plays a role in embryonic heart muscle structure and function, while phosphorylation of the encoded protein is involved in cardiac myosin cycling kinetics, torsion and function in adults. Mutations in this gene are associated with hypertrophic cardiomyopathy 10 and infant-onset myopathy. [provided by RefSeq, May 2022] Expression Restricted expression toward heart (RPKM 6074.6) See more Orthologs mouse all