FRAS1, Official Symbol FRAS1provided by HGNC Official Full Name Fraser extracellular matrix complex subunit 1provided by HGNC Primary source HGNC:HGNC:19185 See related Ensembl:ENSG00000138759 MIM:607830; AllianceGenome:HGNC:19185 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FRASRS1 Summary This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development. Mutations in this gene cause Fraser syndrome, a multisystem malformation that can include craniofacial, urogenital and respiratory system abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] Expression Broad expression in thyroid (RPKM 6.8), kidney (RPKM 4.0) and 15 other tissues See more Orthologs mouse all