ZNF606, Official Symbol ZNF606provided by HGNC Official Full Name zinc finger protein 606provided by HGNC Primary source HGNC:HGNC:25879 See related Ensembl:ENSG00000166704 MIM:613905; AllianceGenome:HGNC:25879 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF328 Summary This gene encodes a zinc finger protein containing a Kruppel-associated box (KRAB) domain at its N-terminus, followed by contiguous C2H2 zinc finger motifs. The encoded protein is a nuclear protein that can act as a transcriptional repressor of growth factor-mediated signaling pathways in a reporter gene assay. This protein has been shown to interact with the SRY-box 9 gene product, and suppresses its transcriptional activity by inhibiting its DNA binding activity. Reduced expression of this gene promotes chondrocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016] Expression Ubiquitous expression in thyroid (RPKM 3.6), testis (RPKM 3.3) and 25 other tissues See more Orthologs mouse all