WWC2, Official Symbol WWC2provided by HGNC Official Full Name WW and C2 domain containing 2provided by HGNC Primary source HGNC:HGNC:24148 See related Ensembl:ENSG00000151718 MIM:620110; AllianceGenome:HGNC:24148 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BOMB Summary This gene encodes a member of the WW-and-C2-domain-containing family of proteins. Members of this family have two N-terminal WW domains that mediate binding to target proteins harboring L/PPxY motifs, an internal C2 domain for membrane association, and C-terminal alpha protein kinase C binding sites and class III PDZ domain-interaction motifs. Proteins of this family are able to form homo- and heterodimers and to modulate hippo pathway signaling. [provided by RefSeq, Sep 2016] Expression Broad expression in lung (RPKM 16.2), kidney (RPKM 8.8) and 23 other tissues See more Orthologs mouse all