PPA1, Official Symbol PPA1provided by HGNC Official Full Name inorganic pyrophosphatase 1provided by HGNC Primary source HGNC:HGNC:9226 See related Ensembl:ENSG00000180817 MIM:179030; AllianceGenome:HGNC:9226 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP; PP1; IOPPP; HEL-S-66p; SID6-8061 Summary The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in adrenal (RPKM 81.3), colon (RPKM 70.8) and 25 other tissues See more Orthologs mouse all