PYDC1, Official Symbol PYDC1provided by HGNC Official Full Name pyrin domain containing 1provided by HGNC Primary source HGNC:HGNC:30261 See related Ensembl:ENSG00000169900 MIM:615700; AllianceGenome:HGNC:30261 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ASC2; POP1; PYC1; cPOP1 Summary Predicted to enable cysteine-type endopeptidase activity. Involved in several processes, including negative regulation of tumor necrosis factor-mediated signaling pathway; regulation of gene expression; and tumor necrosis factor-mediated signaling pathway. Located in cytosol and nucleus. Part of IkappaB kinase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in skin (RPKM 1.7), brain (RPKM 0.2) and 1 other tissue See more Orthologs all