CHRNB2, Official Symbol CHRNB2provided by HGNC Official Full Name cholinergic receptor nicotinic beta 2 subunitprovided by HGNC Primary source HGNC:HGNC:1962 See related Ensembl:ENSG00000160716 MIM:118507; AllianceGenome:HGNC:1962 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EFNL3; nAChRB2 Summary Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 9.5), adrenal (RPKM 0.7) and 1 other tissue See more Orthologs mouse all