PAQR3, Official Symbol PAQR3provided by HGNC Official Full Name progestin and adipoQ receptor family member 3provided by HGNC Primary source HGNC:HGNC:30130 See related Ensembl:ENSG00000163291 MIM:614577; AllianceGenome:HGNC:30130 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RKTG Summary This gene encodes a seven-transmembrane protein localized in the Golgi apparatus in mammalian cells. The encoded protein belongs to the progestin and adipoQ receptor (PAQR) family. This protein functions as a tumor suppressor by inhibiting the Raf/MEK/ERK signaling cascade. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017] Expression Broad expression in testis (RPKM 20.7), brain (RPKM 8.5) and 24 other tissues See more Orthologs mouse all