EXOG, Official Symbol EXOGprovided by HGNC Official Full Name exo/endonuclease Gprovided by HGNC Primary source HGNC:HGNC:3347 See related Ensembl:ENSG00000157036 MIM:604051; AllianceGenome:HGNC:3347 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ENGL; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2 Summary This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009] Expression Ubiquitous expression in heart (RPKM 2.2), lymph node (RPKM 1.6) and 25 other tissues See more Orthologs mouse all