SELE, Official Symbol SELEprovided by HGNC Official Full Name selectin Eprovided by HGNC Primary source HGNC:HGNC:10718 See related Ensembl:ENSG00000007908 MIM:131210; AllianceGenome:HGNC:10718 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ELAM; ESEL; CD62E; ELAM1; LECAM2; selectin-e Summary The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008] Expression Biased expression in prostate (RPKM 16.5), urinary bladder (RPKM 15.5) and 12 other tissues See more Orthologs mouse all