LDB2, Official Symbol LDB2provided by HGNC Official Full Name LIM domain binding 2provided by HGNC Primary source HGNC:HGNC:6533 See related Ensembl:ENSG00000169744 MIM:603450; AllianceGenome:HGNC:6533 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LDB1; CLIM1; LDB-2 Summary The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Expression Broad expression in endometrium (RPKM 25.9), fat (RPKM 24.8) and 23 other tissues See more Orthologs mouse all