NR0B1, Official Symbol NR0B1provided by HGNC Official Full Name nuclear receptor subfamily 0 group B member 1provided by HGNC Primary source HGNC:HGNC:7960 See related Ensembl:ENSG00000169297 MIM:300473; AllianceGenome:HGNC:7960 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AHC; AHX; DSS; GTD; HHG; AHCH; DAX1; DAX-1; NROB1; SRXY2 Summary This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008] Expression Biased expression in testis (RPKM 9.2), adrenal (RPKM 6.6) and 1 other tissue See more Orthologs mouse all