CDK12, Official Symbol CDK12provided by HGNC Official Full Name cyclin dependent kinase 12provided by HGNC Primary source HGNC:HGNC:24224 See related Ensembl:ENSG00000167258 MIM:615514; AllianceGenome:HGNC:24224 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRK7; CRKR; CRKRS Summary Enables RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation; and regulation of MAP kinase activity. Located in nuclear speck. Part of cyclin K-CDK12 complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 8.6), bone marrow (RPKM 8.1) and 25 other tissues See more Orthologs mouse all