GPR21, Official Symbol GPR21provided by HGNC Official Full Name G protein-coupled receptor 21provided by HGNC Primary source HGNC:HGNC:4476 See related Ensembl:ENSG00000188394 MIM:601909; AllianceGenome:HGNC:4476 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the G-protein-coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. The encoded protein activates a Gq signal transduction pathway which mobilizes calcium. [provided by RefSeq, Nov 2012] Expression Low expression observed in reference dataset See more Orthologs mouse all