CALB1, Official Symbol CALB1provided by HGNC Official Full Name calbindin 1provided by HGNC Primary source HGNC:HGNC:1434 See related Ensembl:ENSG00000104327 MIM:114050; AllianceGenome:HGNC:1434 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CALB; D-28K Summary The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015] Expression Restricted expression toward kidney (RPKM 156.4) See more Orthologs mouse all