PROK2, Official Symbol PROK2provided by HGNC Official Full Name prokineticin 2provided by HGNC Primary source HGNC:HGNC:18455 See related Ensembl:ENSG00000163421 MIM:607002; AllianceGenome:HGNC:18455 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BV8; HH4; PK2; KAL4; MIT1 Summary This gene encodes a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 18.5), appendix (RPKM 9.5) and 4 other tissues See more Orthologs mouse all