CALCOCO2, Official Symbol CALCOCO2provided by HGNC Official Full Name calcium binding and coiled-coil domain 2provided by HGNC Primary source HGNC:HGNC:29912 See related Ensembl:ENSG00000136436 MIM:604587; AllianceGenome:HGNC:29912 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NDP52 Summary This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] Expression Ubiquitous expression in fat (RPKM 39.0), testis (RPKM 32.6) and 25 other tissues See more Orthologs mouse all