PPP6R3, Official Symbol PPP6R3provided by HGNC Official Full Name protein phosphatase 6 regulatory subunit 3provided by HGNC Primary source HGNC:HGNC:1173 See related Ensembl:ENSG00000110075 MIM:610879; AllianceGenome:HGNC:1173 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAPL; PP6R3; SAPLa; SAPS3; SAP190; C11orf23 Summary Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010] Expression Ubiquitous expression in thyroid (RPKM 14.0), testis (RPKM 11.4) and 25 other tissues See more Orthologs mouse all