PIGN, Official Symbol PIGNprovided by HGNC Official Full Name phosphatidylinositol glycan anchor biosynthesis class Nprovided by HGNC Primary source HGNC:HGNC:8967 See related Ensembl:ENSG00000197563 MIM:606097; AllianceGenome:HGNC:8967 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCD4; MDC4; MCAHS; PIG-N; MCAHS1 Summary This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in esophagus (RPKM 8.5), thyroid (RPKM 7.2) and 25 other tissues See more Orthologs mouse all