GPR68, Official Symbol GPR68provided by HGNC Official Full Name G protein-coupled receptor 68provided by HGNC Primary source HGNC:HGNC:4519 See related Ensembl:ENSG00000119714 MIM:601404; AllianceGenome:HGNC:4519 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OGR1; AI2A6; GPR12A Summary The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017] Expression Broad expression in appendix (RPKM 1.7), skin (RPKM 1.5) and 22 other tissues See more Orthologs mouse all