PPARG, Official Symbol PPARGprovided by HGNC Official Full Name peroxisome proliferator activated receptor gammaprovided by HGNC Primary source HGNC:HGNC:9236 See related Ensembl:ENSG00000132170 MIM:601487; AllianceGenome:HGNC:9236 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma Summary This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in fat (RPKM 44.7), urinary bladder (RPKM 10.3) and 11 other tissues See more Orthologs mouse all