JOSD2, Official Symbol JOSD2provided by HGNC Official Full Name Josephin domain containing 2provided by HGNC Primary source HGNC:HGNC:28853 See related Ensembl:ENSG00000161677 MIM:615324; AllianceGenome:HGNC:28853 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SBBI54 Summary This gene encodes a protein containing a Josephin domain. Josephin domain-containing proteins are deubiquitinating enzymes which catalyze the hydrolysis of the bond between the C-terminal glycine of the ubiquitin peptide and protein substrates. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] Expression Ubiquitous expression in fat (RPKM 7.4), stomach (RPKM 6.8) and 25 other tissues See more Orthologs mouse all