NPW, Official Symbol NPWprovided by HGNC Official Full Name neuropeptide Wprovided by HGNC Primary source HGNC:HGNC:30509 See related Ensembl:ENSG00000183971 MIM:607997; AllianceGenome:HGNC:30509 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as L8; L8C; PPL8; PPNPW Summary The product of this gene is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 2.8), stomach (RPKM 0.8) and 1 other tissue See more Orthologs mouse all