CCK, Official Symbol CCKprovided by HGNC Official Full Name cholecystokininprovided by HGNC Primary source HGNC:HGNC:1569 See related Ensembl:ENSG00000187094 MIM:118440; AllianceGenome:HGNC:1569 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015] Expression Biased expression in duodenum (RPKM 21.7), brain (RPKM 20.3) and 2 other tissues See more Orthologs mouse all