ADGRG4, Official Symbol ADGRG4provided by HGNC Official Full Name adhesion G protein-coupled receptor G4provided by HGNC Primary source HGNC:HGNC:18992 See related Ensembl:ENSG00000156920 MIM:301085; AllianceGenome:HGNC:18992 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR17; GPR112; RP1-299I16 Summary This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010] Expression Biased expression in duodenum (RPKM 1.3), small intestine (RPKM 0.8) and 2 other tissues See more Orthologs mouse all