PTBP2, Official Symbol PTBP2provided by HGNC Official Full Name polypyrimidine tract binding protein 2provided by HGNC Primary source HGNC:HGNC:17662 See related Ensembl:ENSG00000117569 MIM:608449; AllianceGenome:HGNC:17662 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as nPTB; PTBLP; brPTB Summary The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Broad expression in testis (RPKM 15.6), brain (RPKM 9.8) and 24 other tissues See more Orthologs mouse all