RNF168, Official Symbol RNF168provided by HGNC Official Full Name ring finger protein 168provided by HGNC Primary source HGNC:HGNC:26661 See related Ensembl:ENSG00000163961 MIM:612688; AllianceGenome:HGNC:26661 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIDL; hRNF168 Summary This gene encodes an E3 ubiquitin ligase protein that contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The protein is involved in DNA double-strand break (DSB) repair. Mutations in this gene result in Riddle syndrome. [provided by RefSeq, Sep 2011] Expression Broad expression in testis (RPKM 13.5), bone marrow (RPKM 9.5) and 24 other tissues See more Orthologs mouse all