EI24, Official Symbol EI24provided by HGNC Official Full Name EI24 autophagy associated transmembrane proteinprovided by HGNC Primary source HGNC:HGNC:13276 See related Ensembl:ENSG00000149547 MIM:605170; AllianceGenome:HGNC:13276 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EPG4; PIG8; TP53I8 Summary This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014] Expression Ubiquitous expression in liver (RPKM 39.6), colon (RPKM 30.4) and 25 other tissues See more Orthologs mouse all