DVL1, Official Symbol DVL1provided by HGNC Official Full Name dishevelled segment polarity protein 1provided by HGNC Primary source HGNC:HGNC:3084 See related Ensembl:ENSG00000107404 MIM:601365; AllianceGenome:HGNC:3084 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DVL; DRS2; DVL1L1; DVL1P1 Summary DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 16.9), fat (RPKM 14.7) and 25 other tissues See more Orthologs mouse all