ELK1, Official Symbol ELK1provided by HGNC Official Full Name ETS transcription factor ELK1provided by HGNC Primary source HGNC:HGNC:3321 See related Ensembl:ENSG00000126767 MIM:311040; AllianceGenome:HGNC:3321 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012] Expression Ubiquitous expression in ovary (RPKM 19.1), brain (RPKM 15.9) and 25 other tissues See more Orthologs mouse all