JAG2, Official Symbol JAG2provided by HGNC Official Full Name jagged canonical Notch ligand 2provided by HGNC Primary source HGNC:HGNC:6189 See related Ensembl:ENSG00000184916 MIM:602570; AllianceGenome:HGNC:6189 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HJ2; SER2; LGMDR27 Summary The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in skin (RPKM 13.9), fat (RPKM 7.0) and 19 other tissues See more Orthologs mouse all