S100A6, Official Symbol S100A6provided by HGNC Official Full Name S100 calcium binding protein A6provided by HGNC Primary source HGNC:HGNC:10496 See related Ensembl:ENSG00000197956 MIM:114110; AllianceGenome:HGNC:10496 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 2A9; PRA; 5B10; CABP; CACY; S10A6 Summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008] Expression Broad expression in colon (RPKM 705.5), lung (RPKM 524.4) and 23 other tissues See more Orthologs mouse all