IKBKB, Official Symbol IKBKBprovided by HGNC Official Full Name inhibitor of nuclear factor kappa B kinase subunit betaprovided by HGNC Primary source HGNC:HGNC:5960 See related Ensembl:ENSG00000104365 MIM:603258; AllianceGenome:HGNC:5960 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IKK2; IKKB; IKK-2; IMD15; IMD15A; IMD15B; NFKBIKB; IKK-beta Summary The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in spleen (RPKM 14.6), lymph node (RPKM 12.4) and 25 other tissues See more Orthologs mouse all