FRMD3, Official Symbol FRMD3provided by HGNC Official Full Name FERM domain containing 3provided by HGNC Primary source HGNC:HGNC:24125 See related Ensembl:ENSG00000172159 MIM:607619; AllianceGenome:HGNC:24125 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 4.1O; P410; EPB41LO; EPB41L4O Summary The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Expression Broad expression in heart (RPKM 8.0), kidney (RPKM 5.0) and 20 other tissues See more Orthologs mouse all