PCDH8, Official Symbol PCDH8provided by HGNC Official Full Name protocadherin 8provided by HGNC Primary source HGNC:HGNC:8660 See related Ensembl:ENSG00000136099 MIM:603580; AllianceGenome:HGNC:8660 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PAPC; ARCADLIN Summary This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 2.9), testis (RPKM 0.5) and 2 other tissues See more Orthologs mouse all