NR4A1, Official Symbol NR4A1provided by HGNC Official Full Name nuclear receptor subfamily 4 group A member 1provided by HGNC Primary source HGNC:HGNC:7980 See related Ensembl:ENSG00000123358 MIM:139139; AllianceGenome:HGNC:7980 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HMR; N10; TR3; NP10; GFRP1; NAK-1; NGFIB; NUR77 Summary This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] Expression Broad expression in adrenal (RPKM 103.3), ovary (RPKM 73.7) and 19 other tissues See more Orthologs mouse all