KLF11, Official Symbol KLF11provided by HGNC Official Full Name KLF transcription factor 11provided by HGNC Primary source HGNC:HGNC:11811 See related Ensembl:ENSG00000172059 MIM:603301; AllianceGenome:HGNC:11811 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FKLF; FKLF1; MODY7; TIEG2; Tieg3 Summary The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] Expression Ubiquitous expression in testis (RPKM 20.2), lung (RPKM 12.4) and 25 other tissues See more Orthologs mouse all