TLX3, Official Symbol TLX3provided by HGNC Official Full Name T cell leukemia homeobox 3provided by HGNC Primary source HGNC:HGNC:13532 See related Ensembl:ENSG00000164438 MIM:604640; AllianceGenome:HGNC:13532 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RNX; HOX11L2 Summary The protein encoded by this gene is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5;14)(q35;q32)] involving this gene is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults. [provided by RefSeq, Nov 2015] Expression Low expression observed in reference dataset See more Orthologs mouse all