PRPS2, Official Symbol PRPS2provided by HGNC Official Full Name phosphoribosyl pyrophosphate synthetase 2provided by HGNC Primary source HGNC:HGNC:9465 See related Ensembl:ENSG00000101911 MIM:311860; AllianceGenome:HGNC:9465 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRSII Summary This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] Expression Broad expression in testis (RPKM 94.5), adrenal (RPKM 26.5) and 22 other tissues See more Orthologs mouse all