KCNK16, Official Symbol KCNK16provided by HGNC Official Full Name potassium two pore domain channel subfamily K member 16provided by HGNC Primary source HGNC:HGNC:14464 See related Ensembl:ENSG00000095981 MIM:607369; AllianceGenome:HGNC:14464 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TALK1; TALK-1; K2p16.1 Summary The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008] Expression Biased expression in stomach (RPKM 3.5), pancreas (RPKM 1.4) and 2 other tissues See more Orthologs mouse all