ARL2BP, Official Symbol ARL2BPprovided by HGNC Official Full Name ADP ribosylation factor like GTPase 2 binding proteinprovided by HGNC Primary source HGNC:HGNC:17146 See related Ensembl:ENSG00000102931 MIM:615407; AllianceGenome:HGNC:17146 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BART; RP66; BART1 Summary ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 36.7), fat (RPKM 27.6) and 25 other tissues See more Orthologs mouse all