KLHL25, Official Symbol KLHL25provided by HGNC Official Full Name kelch like family member 25provided by HGNC Primary source HGNC:HGNC:25732 See related Ensembl:ENSG00000183655 MIM:619893; AllianceGenome:HGNC:25732 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ENC2; ENC-2 Summary Involved in protein ubiquitination; regulation of translational initiation; and ubiquitin-dependent protein catabolic process. Located in cytoplasm. Part of Cul3-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in brain (RPKM 6.7), testis (RPKM 5.6) and 23 other tissues See more Orthologs mouse all