PLPPR4, Official Symbol PLPPR4provided by HGNC Official Full Name phospholipid phosphatase related 4provided by HGNC Primary source HGNC:HGNC:23496 See related Ensembl:ENSG00000117600 MIM:607813; AllianceGenome:HGNC:23496 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LPR4; PHP1; PRG1; LPPR4; PRG-1 Summary The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] Expression Biased expression in brain (RPKM 35.4), testis (RPKM 3.7) and 2 other tissues See more Orthologs mouse all