FGF9, Official Symbol FGF9provided by HGNC Official Full Name fibroblast growth factor 9provided by HGNC Primary source HGNC:HGNC:3687 See related Ensembl:ENSG00000102678 MIM:600921; AllianceGenome:HGNC:3687 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GAF; FGF-9; SYNS3; HBFG-9; HBGF-9 Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 6.4), adrenal (RPKM 2.1) and 10 other tissues See more Orthologs mouse all