AGO2, Official Symbol AGO2provided by HGNC Official Full Name argonaute RISC catalytic component 2provided by HGNC Primary source HGNC:HGNC:3263 See related Ensembl:ENSG00000123908 MIM:606229; AllianceGenome:HGNC:3263 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PPD; Q10; CASC7; EIF2C2; LESKRES; LINC00980 Summary This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Expression Ubiquitous expression in skin (RPKM 3.3), ovary (RPKM 3.3) and 25 other tissues See more Orthologs mouse all