NFATC2, Official Symbol NFATC2provided by HGNC Official Full Name nuclear factor of activated T cells 2provided by HGNC Primary source HGNC:HGNC:7776 See related Ensembl:ENSG00000101096 MIM:600490; AllianceGenome:HGNC:7776 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JCOSL; NFAT1; NFATP Summary This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012] Expression Broad expression in gall bladder (RPKM 9.1), lymph node (RPKM 6.9) and 25 other tissues See more Orthologs mouse all