CCL27, Official Symbol CCL27provided by HGNC Official Full Name C-C motif chemokine ligand 27provided by HGNC Primary source HGNC:HGNC:10626 See related Ensembl:ENSG00000213927 MIM:604833; AllianceGenome:HGNC:10626 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27 Summary This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014] Expression Biased expression in skin (RPKM 77.8), spleen (RPKM 8.8) and 11 other tissues See more Orthologs mouse all