PDE3B, Official Symbol PDE3Bprovided by HGNC Official Full Name phosphodiesterase 3Bprovided by HGNC Primary source HGNC:HGNC:8779 See related Ensembl:ENSG00000152270 MIM:602047; AllianceGenome:HGNC:8779 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HcGIP1; cGIPDE1 Summary Enables 3',5'-cyclic-nucleotide phosphodiesterase activity. Involved in negative regulation of angiogenesis; negative regulation of cell adhesion; and negative regulation of lipid catabolic process. Located in membrane. Part of guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in fat (RPKM 53.0), lymph node (RPKM 8.6) and 12 other tissues See more Orthologs mouse all