TMPRSS9, Official Symbol TMPRSS9provided by HGNC Official Full Name transmembrane serine protease 9provided by HGNC Primary source HGNC:HGNC:30079 See related Ensembl:ENSG00000178297 MIM:610477; AllianceGenome:HGNC:30079 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a membrane-bound type II serine polyprotease that is cleaved to release three different proteases. Two of the proteases are active and can be inhibited by serine protease inhibitors, and one is thought to be catalytically inactive. This gene enhances the invasive capability of pancreatic cancer cells and may be involved in cancer progression. [provided by RefSeq, Jul 2016] Expression Broad expression in spleen (RPKM 1.4), testis (RPKM 1.2) and 25 other tissues See more Orthologs mouse all