VEGFD, Official Symbol VEGFDprovided by HGNC Official Full Name vascular endothelial growth factor Dprovided by HGNC Primary source HGNC:HGNC:3708 See related Ensembl:ENSG00000165197 MIM:300091; AllianceGenome:HGNC:3708 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FIGF; VEGF-D Summary The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011] Expression Biased expression in lung (RPKM 21.7), fat (RPKM 4.7) and 9 other tissues See more Orthologs mouse all