MAD2L1, Official Symbol MAD2L1provided by HGNC Official Full Name mitotic arrest deficient 2 like 1provided by HGNC Primary source HGNC:HGNC:6763 See related Ensembl:ENSG00000164109 MIM:601467; AllianceGenome:HGNC:6763 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MAD2; HSMAD2 Summary MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008] Expression Broad expression in bone marrow (RPKM 15.9), lymph node (RPKM 15.1) and 23 other tissues See more Orthologs mouse all