DPP10, Official Symbol DPP10provided by HGNC Official Full Name dipeptidyl peptidase like 10provided by HGNC Primary source HGNC:HGNC:20823 See related Ensembl:ENSG00000175497 MIM:608209; AllianceGenome:HGNC:20823 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DPL2; DPPY; DPRP3; DPRP-3 Summary This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 7.5), adrenal (RPKM 2.9) and 2 other tissues See more Orthologs mouse all