CYP4F8, Official Symbol CYP4F8provided by HGNC Official Full Name cytochrome P450 family 4 subfamily F member 8provided by HGNC Primary source HGNC:HGNC:2648 See related Ensembl:ENSG00000186526 MIM:611545; AllianceGenome:HGNC:2648 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPF8; CYPIVF8 Summary This gene, CYP4F8, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and functions as a 19-hydroxylase of prostaglandins in seminal vesicles. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F3, is approximately 18 kb away. [provided by RefSeq, Jul 2008] Expression Biased expression in prostate (RPKM 2.3), skin (RPKM 0.2) and 2 other tissues See more Orthologs all