SCN4B, Official Symbol SCN4Bprovided by HGNC Official Full Name sodium voltage-gated channel beta subunit 4provided by HGNC Primary source HGNC:HGNC:10592 See related Ensembl:ENSG00000177098 MIM:608256; AllianceGenome:HGNC:10592 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LQT10; ATFB17; Navbeta4 Summary The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009] Expression Broad expression in fat (RPKM 19.5), brain (RPKM 8.6) and 18 other tissues See more Orthologs mouse all