HTR3B, Official Symbol HTR3Bprovided by HGNC Official Full Name 5-hydroxytryptamine receptor 3Bprovided by HGNC Primary source HGNC:HGNC:5298 See related Ensembl:ENSG00000149305 MIM:604654; AllianceGenome:HGNC:5298 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 5-HT3B Summary The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011] Expression Low expression observed in reference dataset See more Orthologs mouse all