ELAVL1, Official Symbol ELAVL1provided by HGNC Official Full Name ELAV like RNA binding protein 1provided by HGNC Primary source HGNC:HGNC:3312 See related Ensembl:ENSG00000066044 MIM:603466; AllianceGenome:HGNC:3312 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HUR; Hua; MelG; ELAV1 Summary The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012] Expression Ubiquitous expression in testis (RPKM 14.6), brain (RPKM 9.9) and 25 other tissues See more Orthologs mouse all