TTPA, Official Symbol TTPAprovided by HGNC Official Full Name alpha tocopherol transfer proteinprovided by HGNC Primary source HGNC:HGNC:12404 See related Ensembl:ENSG00000137561 MIM:600415; AllianceGenome:HGNC:12404 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATTP; AVED; TTP1; alphaTTP Summary This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa. [provided by RefSeq, Nov 2009] Expression Biased expression in liver (RPKM 30.1) and colon (RPKM 1.4) See more Orthologs mouse all