CD80, Official Symbol CD80provided by HGNC Official Full Name CD80 moleculeprovided by HGNC Primary source HGNC:HGNC:1700 See related Ensembl:ENSG00000121594 MIM:112203; AllianceGenome:HGNC:1700 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1 Summary The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in appendix (RPKM 2.0), lymph node (RPKM 1.9) and 24 other tissues See more Orthologs mouse all