THOC6, Official Symbol THOC6provided by HGNC Official Full Name THO complex subunit 6provided by HGNC Primary source HGNC:HGNC:28369 See related Ensembl:ENSG00000131652 MIM:615403; AllianceGenome:HGNC:28369 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WDR58; fSAP35; MMRFCGU Summary This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/export) complex, which is involved in transcription and export of mRNAs. A missense mutation in this gene is associated with a neurodevelopmental disorder called Beaulieu-Boycott-Innes syndrome. [provided by RefSeq, Dec 2016] Expression Ubiquitous expression in placenta (RPKM 12.6), skin (RPKM 10.4) and 25 other tissues See more Orthologs mouse all