AGER, Official Symbol AGERprovided by HGNC Official Full Name advanced glycosylation end-product specific receptorprovided by HGNC Primary source HGNC:HGNC:320 See related Ensembl:ENSG00000204305 MIM:600214; AllianceGenome:HGNC:320 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RAGE; sRAGE; SCARJ1 Summary The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011] Expression Biased expression in lung (RPKM 397.6) and spleen (RPKM 11.0) See more Orthologs mouse all