OTOA, Official Symbol OTOAprovided by HGNC Official Full Name otoancorinprovided by HGNC Primary source HGNC:HGNC:16378 See related Ensembl:ENSG00000155719 MIM:607038; AllianceGenome:HGNC:16378 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT108; DFNB22 Summary The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] Expression Biased expression in testis (RPKM 1.9), spleen (RPKM 0.7) and 4 other tissues See more Orthologs mouse all