CISD2, Official Symbol CISD2provided by HGNC Official Full Name CDGSH iron sulfur domain 2provided by HGNC Primary source HGNC:HGNC:24212 See related Ensembl:ENSG00000145354 MIM:611507; AllianceGenome:HGNC:24212 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ERIS; WFS2; ZCD2; NAF-1; Miner1 Summary The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011] Expression Ubiquitous expression in thyroid (RPKM 8.6), kidney (RPKM 5.5) and 25 other tissues See more Orthologs mouse all