CARTPT, Official Symbol CARTPTprovided by HGNC Official Full Name CART prepropeptideprovided by HGNC Primary source HGNC:HGNC:24323 See related Ensembl:ENSG00000164326 MIM:602606; AllianceGenome:HGNC:24323 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CART Summary This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans. [provided by RefSeq, Feb 2016] Expression Biased expression in adrenal (RPKM 51.3), brain (RPKM 5.7) and 1 other tissue See more Orthologs mouse all