EZH2, Official Symbol EZH2provided by HGNC Official Full Name enhancer of zeste 2 polycomb repressive complex 2 subunitprovided by HGNC Primary source HGNC:HGNC:3527 See related Ensembl:ENSG00000106462 MIM:601573; AllianceGenome:HGNC:3527 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A Summary This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011] Expression Broad expression in bone marrow (RPKM 9.3), testis (RPKM 8.6) and 14 other tissues See more Orthologs mouse all