ARHGAP6, Official Symbol ARHGAP6provided by HGNC Official Full Name Rho GTPase activating protein 6provided by HGNC Primary source HGNC:HGNC:676 See related Ensembl:ENSG00000047648 MIM:300118; AllianceGenome:HGNC:676 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RHOGAP6; RHOGAPX-1 Summary This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in prostate (RPKM 12.6), thyroid (RPKM 10.2) and 18 other tissues See more Orthologs mouse all