PTPN5, Official Symbol PTPN5provided by HGNC Official Full Name protein tyrosine phosphatase non-receptor type 5provided by HGNC Primary source HGNC:HGNC:9657 See related Ensembl:ENSG00000110786 MIM:176879; AllianceGenome:HGNC:9657 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STEP; STEP61; PTPSTEP Summary Enables phosphotyrosine residue binding activity. Predicted to be involved in peptidyl-tyrosine dephosphorylation. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in nucleoplasm. Predicted to be integral component of membrane. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 11.0), testis (RPKM 0.9) and 1 other tissue See more Orthologs mouse all