SERPINB9, Official Symbol SERPINB9provided by HGNC Official Full Name serpin family B member 9provided by HGNC Primary source HGNC:HGNC:8955 See related Ensembl:ENSG00000170542 MIM:601799; AllianceGenome:HGNC:8955 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PI9; CAP3; PI-9; CAP-3 Summary This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012] Expression Broad expression in placenta (RPKM 26.1), appendix (RPKM 19.1) and 21 other tissues See more Orthologs all