CDC14A, Official Symbol CDC14Aprovided by HGNC Official Full Name cell division cycle 14Aprovided by HGNC Primary source HGNC:HGNC:1718 See related Ensembl:ENSG00000079335 MIM:603504; AllianceGenome:HGNC:1718 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as cdc14; DFNB32; DFNB35; hCDC14; DFNB105 Summary The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 5.6), bone marrow (RPKM 3.3) and 24 other tissues See more Orthologs mouse all