CPA1, Official Symbol CPA1provided by HGNC Official Full Name carboxypeptidase A1provided by HGNC Primary source HGNC:HGNC:2296 See related Ensembl:ENSG00000091704 MIM:114850; AllianceGenome:HGNC:2296 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPA Summary This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015] Expression Restricted expression toward pancreas (RPKM 26661.6) See more Orthologs mouse all