EXOC5, Official Symbol EXOC5provided by HGNC Official Full Name exocyst complex component 5provided by HGNC Primary source HGNC:HGNC:10696 See related Ensembl:ENSG00000070367 MIM:604469; AllianceGenome:HGNC:10696 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SEC10; HSEC10; SEC10P; PRO1912; SEC10L1 Summary The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 17.5), brain (RPKM 9.4) and 25 other tissues See more Orthologs mouse all