CREB3L1, Official Symbol CREB3L1provided by HGNC Official Full Name cAMP responsive element binding protein 3 like 1provided by HGNC Primary source HGNC:HGNC:18856 See related Ensembl:ENSG00000157613 MIM:616215; AllianceGenome:HGNC:18856 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OI16; OASIS; DEL16p11.2; C16DELp11.2 Summary The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements. [provided by RefSeq, Jun 2013] Expression Broad expression in stomach (RPKM 29.2), colon (RPKM 23.7) and 16 other tissues See more Orthologs mouse all