TFPI2, Official Symbol TFPI2provided by HGNC Official Full Name tissue factor pathway inhibitor 2provided by HGNC Primary source HGNC:HGNC:11761 See related Ensembl:ENSG00000105825 MIM:600033; AllianceGenome:HGNC:11761 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PP5; REF1; TFPI-2 Summary This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] Expression Biased expression in placenta (RPKM 566.0) and fat (RPKM 18.9) See more Orthologs mouse all