SLC16A3, Official Symbol SLC16A3provided by HGNC Official Full Name solute carrier family 16 member 3provided by HGNC Primary source HGNC:HGNC:10924 See related Ensembl:ENSG00000141526 MIM:603877; AllianceGenome:HGNC:10924 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCT3; MCT4; MCT 3; MCT 4; MCT-3; MCT-4 Summary Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008] Expression Broad expression in placenta (RPKM 10.2), appendix (RPKM 8.8) and 22 other tissues See more Orthologs mouse all