ADAP2, Official Symbol ADAP2provided by HGNC Official Full Name ArfGAP with dual PH domains 2provided by HGNC Primary source HGNC:HGNC:16487 See related Ensembl:ENSG00000184060 MIM:608635; AllianceGenome:HGNC:16487 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CENTA2; cent-b; HSA272195 Summary The protein encoded by this gene binds beta-tubulin and increases the stability of microtubules. The encoded protein can also translocate to the cell membrane and bind phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). In addition, this protein is a GTPase-activating protein for ADP ribosylation factor 6 and may be able to block the entry of some RNA viruses. [provided by RefSeq, Oct 2016] Expression Broad expression in spleen (RPKM 10.3), placenta (RPKM 9.9) and 23 other tissues See more Orthologs mouse all