TOPBP1, Official Symbol TOPBP1provided by HGNC Official Full Name DNA topoisomerase II binding protein 1provided by HGNC Primary source HGNC:HGNC:17008 See related Ensembl:ENSG00000163781 MIM:607760; AllianceGenome:HGNC:17008 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Dpb11; TOP2BP1 Summary This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 16.9), bone marrow (RPKM 13.6) and 25 other tissues See more Orthologs mouse all