SLC4A2, Official Symbol SLC4A2provided by HGNC Official Full Name solute carrier family 4 member 2provided by HGNC Primary source HGNC:HGNC:11028 See related Ensembl:ENSG00000164889 MIM:109280; AllianceGenome:HGNC:11028 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AE2; HKB3; BND3L; NBND3; OPTB9; EPB3L1 Summary This gene encodes a member of the anion exchanger family of membrane transport proteins. The encoded protein regulates intracellular pH, biliary bicarbonate secretion, and chloride uptake. Reduced expression of this gene may be associated with primary biliary cirrhosis (PBC) in human patients, while differential expression of this gene may be associated with malignant hepatocellular carcinoma, colon and gastric cancers. [provided by RefSeq, Nov 2016] Expression Ubiquitous expression in placenta (RPKM 16.3), stomach (RPKM 13.8) and 25 other tissues See more Orthologs mouse all