COX7B, Official Symbol COX7Bprovided by HGNC Official Full Name cytochrome c oxidase subunit 7Bprovided by HGNC Primary source HGNC:HGNC:2291 See related Ensembl:ENSG00000131174 MIM:300885; AllianceGenome:HGNC:2291 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APLCC; LSDMCA2 Summary Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22. [provided by RefSeq, Jun 2011] Expression Ubiquitous expression in heart (RPKM 234.2), kidney (RPKM 174.2) and 24 other tissues See more Orthologs mouse all