FGFBP1, Official Symbol FGFBP1provided by HGNC Official Full Name fibroblast growth factor binding protein 1provided by HGNC Primary source HGNC:HGNC:19695 See related Ensembl:ENSG00000137440 MIM:607737; AllianceGenome:HGNC:19695 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FGFBP; HBP17; FGF-BP; FGF-BP1; FGFBP-1 Summary This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011] Expression Biased expression in esophagus (RPKM 137.5), skin (RPKM 14.8) and 1 other tissue See more Orthologs mouse all