CCT4, Official Symbol CCT4provided by HGNC Official Full Name chaperonin containing TCP1 subunit 4provided by HGNC Primary source HGNC:HGNC:1617 See related Ensembl:ENSG00000115484 MIM:605142; AllianceGenome:HGNC:1617 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SRB; Cctd; CCT-DELTA Summary The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in ovary (RPKM 58.5), testis (RPKM 51.7) and 25 other tissues See more Orthologs mouse all