ARHGAP29, Official Symbol ARHGAP29provided by HGNC Official Full Name Rho GTPase activating protein 29provided by HGNC Primary source HGNC:HGNC:30207 See related Ensembl:ENSG00000137962 MIM:610496; AllianceGenome:HGNC:30207 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PARG1 Summary Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016] Expression Broad expression in lung (RPKM 15.0), thyroid (RPKM 13.9) and 23 other tissues See more Orthologs mouse all