CANX, Official Symbol CANXprovided by HGNC Official Full Name calnexinprovided by HGNC Primary source HGNC:HGNC:1473 See related Ensembl:ENSG00000127022 MIM:114217; AllianceGenome:HGNC:1473 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CNX; P90; IP90 Summary This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018] Expression Ubiquitous expression in thyroid (RPKM 267.4), placenta (RPKM 108.5) and 25 other tissues See more Orthologs mouse all