GPSM1, Official Symbol GPSM1provided by HGNC Official Full Name G protein signaling modulator 1provided by HGNC Primary source HGNC:HGNC:17858 See related Ensembl:ENSG00000160360 MIM:609491; AllianceGenome:HGNC:17858 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AGS3 Summary G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. This gene encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G-protein signaling systems. The protein contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Broad expression in brain (RPKM 5.1), testis (RPKM 4.7) and 24 other tissues See more Orthologs mouse all