CXCL10, Official Symbol CXCL10provided by HGNC Official Full Name C-X-C motif chemokine ligand 10provided by HGNC Primary source HGNC:HGNC:10637 See related Ensembl:ENSG00000169245 MIM:147310; AllianceGenome:HGNC:10637 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10 Summary This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response. Expression Broad expression in appendix (RPKM 54.9), lymph node (RPKM 28.7) and 14 other tissues See more Orthologs all