DYRK3, Official Symbol DYRK3provided by HGNC Official Full Name dual specificity tyrosine phosphorylation regulated kinase 3provided by HGNC Primary source HGNC:HGNC:3094 See related Ensembl:ENSG00000143479 MIM:603497; AllianceGenome:HGNC:3094 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RED; REDK; DYRK5; hYAK3-2 Summary This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 8.5), gall bladder (RPKM 5.7) and 19 other tissues See more Orthologs mouse all