ERAL1, Official Symbol ERAL1provided by HGNC Official Full Name Era like 12S mitochondrial rRNA chaperone 1provided by HGNC Primary source HGNC:HGNC:3424 See related Ensembl:ENSG00000132591 MIM:607435; AllianceGenome:HGNC:3424 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ERA; CEGA; ERA-W; H-ERA; ERAL1A; ERAL1B; HERA-A; HERA-B; PRLTS6 Summary The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] Expression Ubiquitous expression in brain (RPKM 14.7), placenta (RPKM 13.9) and 25 other tissues See more Orthologs mouse all