BAMBI, Official Symbol BAMBIprovided by HGNC Official Full Name BMP and activin membrane bound inhibitorprovided by HGNC Primary source HGNC:HGNC:30251 See related Ensembl:ENSG00000095739 MIM:604444; AllianceGenome:HGNC:30251 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NMA Summary This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008] Expression Broad expression in ovary (RPKM 40.8), adrenal (RPKM 26.5) and 15 other tissues See more Orthologs mouse all