GTF3C6, Official Symbol GTF3C6provided by HGNC Official Full Name general transcription factor IIIC subunit 6provided by HGNC Primary source HGNC:HGNC:20872 See related Ensembl:ENSG00000155115 MIM:611784; AllianceGenome:HGNC:20872 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C6orf51; TFIIIC35; bA397G5.3 Summary RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in prostate (RPKM 34.5), testis (RPKM 28.5) and 25 other tissues See more Orthologs mouse all