GPIHBP1, Official Symbol GPIHBP1provided by HGNC Official Full Name glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1provided by HGNC Primary source HGNC:HGNC:24945 See related Ensembl:ENSG00000277494 MIM:612757; AllianceGenome:HGNC:24945 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HYPL1D; GPI-HBP1 Summary This gene encodes a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] Expression Biased expression in fat (RPKM 74.5), lung (RPKM 16.0) and 2 other tissues See more Orthologs mouse all