NCK1, Official Symbol NCK1provided by HGNC Official Full Name NCK adaptor protein 1provided by HGNC Primary source HGNC:HGNC:7664 See related Ensembl:ENSG00000158092 MIM:600508; AllianceGenome:HGNC:7664 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCK; nck-1; NCKalpha Summary The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010] Expression Ubiquitous expression in lymph node (RPKM 10.1), fat (RPKM 9.3) and 25 other tissues See more Orthologs mouse all