ROCK2, Official Symbol ROCK2provided by HGNC Official Full Name Rho associated coiled-coil containing protein kinase 2provided by HGNC Primary source HGNC:HGNC:10252 See related Ensembl:ENSG00000134318 MIM:604002; AllianceGenome:HGNC:10252 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ROCK-II Summary The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 15.2), colon (RPKM 13.4) and 25 other tissues See more Orthologs mouse all