PAXX, Official Symbol PAXXprovided by HGNC Official Full Name PAXX non-homologous end joining factorprovided by HGNC Primary source HGNC:HGNC:27849 See related Ensembl:ENSG00000148362 MIM:616315; AllianceGenome:HGNC:27849 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as XLS; C9orf142 Summary The protein encoded by this gene plays a role in the nonhomologous end joining (NHEJ) pathway of DNA double-strand break repair. The encoded protein may function to stabilize the Ku70/Ku80 heterodimer to facilitate the assembly and maintain the stability of the NHEJ complex. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in spleen (RPKM 25.7), lymph node (RPKM 14.9) and 25 other tissues See more Orthologs mouse all