DIP2B, Official Symbol DIP2Bprovided by HGNC Official Full Name disco interacting protein 2 homolog Bprovided by HGNC Primary source HGNC:HGNC:29284 See related Ensembl:ENSG00000066084 MIM:611379; AllianceGenome:HGNC:29284 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in brain (RPKM 13.6), skin (RPKM 9.4) and 25 other tissues See more Orthologs mouse all