INTS10, Official Symbol INTS10provided by HGNC Official Full Name integrator complex subunit 10provided by HGNC Primary source HGNC:HGNC:25548 See related Ensembl:ENSG00000104613 MIM:611353; AllianceGenome:HGNC:25548 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as INT10; C8orf35 Summary INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in thyroid (RPKM 19.2), prostate (RPKM 12.2) and 25 other tissues See more Orthologs mouse all