PIK3R2, Official Symbol PIK3R2provided by HGNC Official Full Name phosphoinositide-3-kinase regulatory subunit 2provided by HGNC Primary source HGNC:HGNC:8980 See related Ensembl:ENSG00000105647 MIM:603157; AllianceGenome:HGNC:8980 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p85; MPPH; P85B; MPPH1; p85beta; p85-BETA Summary Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Three transcript variants, one protein coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Apr 2019] Expression Ubiquitous expression in brain (RPKM 16.0), skin (RPKM 12.1) and 25 other tissues See more Orthologs mouse all