WIPI2, Official Symbol WIPI2provided by HGNC Official Full Name WD repeat domain, phosphoinositide interacting 2provided by HGNC Primary source HGNC:HGNC:32225 See related Ensembl:ENSG00000157954 MIM:609225; AllianceGenome:HGNC:32225 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Atg21; ATG18B; CGI-50; IDDSSA; WIPI-2 Summary WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in testis (RPKM 20.8), brain (RPKM 12.7) and 25 other tissues See more Orthologs mouse all