P2RX2, Official Symbol P2RX2provided by HGNC Official Full Name purinergic receptor P2X 2provided by HGNC Primary source HGNC:HGNC:15459 See related Ensembl:ENSG00000187848 MIM:600844; AllianceGenome:HGNC:15459 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as P2X2; DFNA41 Summary The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013] Expression Biased expression in prostate (RPKM 1.9), spleen (RPKM 0.8) and 13 other tissues See more Orthologs mouse all