TMEM129, Official Symbol TMEM129provided by HGNC Official Full Name transmembrane protein 129, E3 ubiquitin ligaseprovided by HGNC Primary source HGNC:HGNC:25137 See related Ensembl:ENSG00000168936 MIM:615975; AllianceGenome:HGNC:25137 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as D4S2561E Summary Enables ubiquitin protein ligase activity. Involved in protein polyubiquitination; retrograde protein transport, ER to cytosol; and ubiquitin-dependent ERAD pathway. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in kidney (RPKM 11.0), thyroid (RPKM 10.1) and 25 other tissues See more Orthologs mouse all