MEFV, Official Symbol MEFVprovided by HGNC Official Full Name MEFV innate immunity regulator, pyrinprovided by HGNC Primary source HGNC:HGNC:6998 See related Ensembl:ENSG00000103313 MIM:608107; AllianceGenome:HGNC:6998 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FMF; MEF; PAAND; TRIM20 Summary This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. [provided by RefSeq, Jul 2008] Expression Biased expression in appendix (RPKM 3.9), spleen (RPKM 3.2) and 11 other tissues See more Orthologs mouse all