BANK1, Official Symbol BANK1provided by HGNC Official Full Name B cell scaffold protein with ankyrin repeats 1provided by HGNC Primary source HGNC:HGNC:18233 See related Ensembl:ENSG00000153064 MIM:610292; AllianceGenome:HGNC:18233 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BANK Summary The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] Expression Biased expression in lymph node (RPKM 39.0), spleen (RPKM 27.4) and 8 other tissues See more Orthologs mouse all