PPP1R14A, Official Symbol PPP1R14Aprovided by HGNC Official Full Name protein phosphatase 1 regulatory inhibitor subunit 14Aprovided by HGNC Primary source HGNC:HGNC:14871 See related Ensembl:ENSG00000167641 MIM:608153; AllianceGenome:HGNC:14871 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPI17; CPI-17; PPP1INL Summary The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011] Expression Broad expression in fat (RPKM 20.4), spleen (RPKM 15.6) and 20 other tissues See more Orthologs mouse all