CRTC3, Official Symbol CRTC3provided by HGNC Official Full Name CREB regulated transcription coactivator 3provided by HGNC Primary source HGNC:HGNC:26148 See related Ensembl:ENSG00000140577 MIM:608986; AllianceGenome:HGNC:26148 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TORC3; TORC-3 Summary This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012] Expression Ubiquitous expression in ovary (RPKM 20.6), fat (RPKM 11.8) and 25 other tissues See more Orthologs mouse all