DGKI, Official Symbol DGKIprovided by HGNC Official Full Name diacylglycerol kinase iotaprovided by HGNC Primary source HGNC:HGNC:2855 See related Ensembl:ENSG00000157680 MIM:604072; AllianceGenome:HGNC:2855 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DGK-IOTA Summary This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008] Expression Biased expression in thyroid (RPKM 5.1), brain (RPKM 1.6) and 1 other tissue See more Orthologs mouse all