TLX2, Official Symbol TLX2provided by HGNC Official Full Name T cell leukemia homeobox 2provided by HGNC Primary source HGNC:HGNC:5057 See related Ensembl:ENSG00000115297 MIM:604240; AllianceGenome:HGNC:5057 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCX; HOX11L1 Summary This gene is a member of an orphan homeobox-containing transcription factor family. Studies of the mouse ortholog have shown that the encoded protein is crucial for the development of the enteric nervous system; in humans, loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors. [provided by RefSeq, May 2010] Expression Low expression observed in reference dataset See more Orthologs mouse all