DOLK, Official Symbol DOLKprovided by HGNC Official Full Name dolichol kinaseprovided by HGNC Primary source HGNC:HGNC:23406 See related Ensembl:ENSG00000175283 MIM:610746; AllianceGenome:HGNC:23406 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DK; DK1; CDG1M; SEC59; TMEM15 Summary The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.[provided by RefSeq, Apr 2010] Orthologs mouse all