KLRG1, Official Symbol KLRG1provided by HGNC Official Full Name killer cell lectin like receptor G1provided by HGNC Primary source HGNC:HGNC:6380 See related Ensembl:ENSG00000139187 MIM:604874; AllianceGenome:HGNC:6380 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 2F1; MAFA; MAFA-L; CLEC15A; MAFA-2F1; MAFA-LIKE Summary Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016] Expression Broad expression in lymph node (RPKM 2.3), spleen (RPKM 2.1) and 23 other tissues See more Orthologs mouse all