BMX, Official Symbol BMXprovided by HGNC Official Full Name BMX non-receptor tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:1079 See related Ensembl:ENSG00000102010 MIM:300101; AllianceGenome:HGNC:1079 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ETK; PSCTK2; PSCTK3 Summary This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] Expression Broad expression in bone marrow (RPKM 2.4), placenta (RPKM 2.2) and 21 other tissues See more Orthologs mouse all