SH3BP5L, Official Symbol SH3BP5Lprovided by HGNC Official Full Name SH3 binding domain protein 5 likeprovided by HGNC Primary source HGNC:HGNC:29360 See related Ensembl:ENSG00000175137 AllianceGenome:HGNC:29360 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction and negative regulation of protein tyrosine kinase activity. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in skin (RPKM 5.3), brain (RPKM 5.2) and 25 other tissues See more Orthologs mouse all