CPZ, Official Symbol CPZprovided by HGNC Official Full Name carboxypeptidase Zprovided by HGNC Primary source HGNC:HGNC:2333 See related Ensembl:ENSG00000109625 MIM:603105; AllianceGenome:HGNC:2333 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the metallocarboxypeptidase family. This enzyme displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Expression Biased expression in ovary (RPKM 47.9), placenta (RPKM 26.8) and 8 other tissues See more Orthologs mouse all