ARF3, Official Symbol ARF3provided by HGNC Official Full Name ADP ribosylation factor 3provided by HGNC Primary source HGNC:HGNC:654 See related Ensembl:ENSG00000134287 MIM:103190; AllianceGenome:HGNC:654 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. [provided by RefSeq, Oct 2022] Expression Ubiquitous expression in brain (RPKM 69.0), colon (RPKM 28.8) and 24 other tissues See more Orthologs mouse all