HECW1, Official Symbol HECW1provided by HGNC Official Full Name HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1provided by HGNC Primary source HGNC:HGNC:22195 See related Ensembl:ENSG00000002746 MIM:610384; AllianceGenome:HGNC:22195 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NEDL1 Summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of sodium ion transmembrane transporter activity; and regulation of dendrite morphogenesis. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in kidney (RPKM 3.0), brain (RPKM 2.6) and 3 other tissues See more Orthologs mouse all