PSCA, Official Symbol PSCAprovided by HGNC Official Full Name prostate stem cell antigenprovided by HGNC Primary source HGNC:HGNC:9500 See related Ensembl:ENSG00000167653 MIM:602470; AllianceGenome:HGNC:9500 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRO232; lncPSCA Summary This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] Expression Biased expression in stomach (RPKM 721.2), urinary bladder (RPKM 108.9) and 1 other tissue See more Orthologs mouse all