TPI1, Official Symbol TPI1provided by HGNC Official Full Name triosephosphate isomerase 1provided by HGNC Primary source HGNC:HGNC:12009 See related Ensembl:ENSG00000111669 MIM:190450; AllianceGenome:HGNC:12009 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TIM; TPI; TPID; HEL-S-49 Summary This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] Expression Ubiquitous expression in heart (RPKM 181.7), brain (RPKM 179.1) and 25 other tissues See more Orthologs mouse all