DLEU2, Official Symbol DLEU2provided by HGNC Official Full Name deleted in lymphocytic leukemia 2provided by HGNC Primary source HGNC:HGNC:13748 See related Ensembl:ENSG00000231607 MIM:605766; AllianceGenome:HGNC:13748 Gene type ncRNA RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALT1; DLB2; LEU2; RFP2; BCMSUN; RFP2OS; MIR15AHG; TRIM13OS; LINC00022; NCRNA00022 Summary This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferation. However, an alternative transcript produced at this locus was also found to promote progression through the cell cycle via angiotensin I converting enzyme 2 and cyclin D1. [provided by RefSeq, Dec 2017] Expression Ubiquitous expression in bone marrow (RPKM 1.5), testis (RPKM 1.3) and 25 other tissues See more