CACNA1S, Official Symbol CACNA1Sprovided by HGNC Official Full Name calcium voltage-gated channel subunit alpha1 Sprovided by HGNC Primary source HGNC:HGNC:1397 See related Ensembl:ENSG00000081248 MIM:114208; AllianceGenome:HGNC:1397 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MHS5; DHPRM; HOKPP; TTPP1; CMYP18; Cav1.1; HOKPP1; hypoPP; CCHL1A3; CACNL1A3 Summary This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul 2008] Expression Biased expression in esophagus (RPKM 1.7), prostate (RPKM 1.6) and 4 other tissues See more Orthologs mouse all