DNAAF4, Official Symbol DNAAF4provided by HGNC Official Full Name dynein axonemal assembly factor 4provided by HGNC Primary source HGNC:HGNC:21493 See related Ensembl:ENSG00000256061 MIM:608706; AllianceGenome:HGNC:21493 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RD; DYX1; EKN1; DYXC1; CILD25; DYX1C1 Summary This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene. [provided by RefSeq, Mar 2011] Expression Broad expression in testis (RPKM 4.6), thyroid (RPKM 3.5) and 15 other tissues See more Orthologs mouse all