ART4, Official Symbol ART4provided by HGNC Official Full Name ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)provided by HGNC Primary source HGNC:HGNC:726 See related Ensembl:ENSG00000111339 MIM:110600; AllianceGenome:HGNC:726 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DO; DOK1; ARTC4; CD297; DO/ART4 Summary This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008] Expression Biased expression in liver (RPKM 8.6), spleen (RPKM 7.9) and 11 other tissues See more Orthologs mouse all