SSTR1, Official Symbol SSTR1provided by HGNC Official Full Name somatostatin receptor 1provided by HGNC Primary source HGNC:HGNC:11330 See related Ensembl:ENSG00000139874 MIM:182451; AllianceGenome:HGNC:11330 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SS1R; SST1; SS1-R; SRIF-2; SS-1-R Summary Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012] Expression Biased expression in stomach (RPKM 11.3), duodenum (RPKM 7.3) and 9 other tissues See more Orthologs mouse all