PLA2G4B, Official Symbol PLA2G4Bprovided by HGNC Official Full Name phospholipase A2 group IVBprovided by HGNC Primary source HGNC:HGNC:9036 See related Ensembl:ENSG00000243708 MIM:606088; AllianceGenome:HGNC:9036 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HsT16992; cPLA2-beta Summary This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through transcripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic phospholipase A2 domains. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in skin (RPKM 29.6), esophagus (RPKM 11.9) and 23 other tissues See more Orthologs mouse all