SH2B1, Official Symbol SH2B1provided by HGNC Official Full Name SH2B adaptor protein 1provided by HGNC Primary source HGNC:HGNC:30417 See related Ensembl:ENSG00000178188 MIM:608937; AllianceGenome:HGNC:30417 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PSM; SH2B Summary This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009] Expression Ubiquitous expression in ovary (RPKM 12.3), spleen (RPKM 12.2) and 25 other tissues See more Orthologs mouse all