CXCL14, Official Symbol CXCL14provided by HGNC Official Full Name C-X-C motif chemokine ligand 14provided by HGNC Primary source HGNC:HGNC:10640 See related Ensembl:ENSG00000145824 MIM:604186; AllianceGenome:HGNC:10640 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KEC; KS1; BMAC; BRAK; NJAC; MIP2G; MIP-2g; SCYB14 Summary This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Sep 2014] Expression Biased expression in skin (RPKM 295.1), kidney (RPKM 161.0) and 13 other tissues See more Orthologs mouse all