MSX1, Official Symbol MSX1provided by HGNC Official Full Name msh homeobox 1provided by HGNC Primary source HGNC:HGNC:7391 See related Ensembl:ENSG00000163132 MIM:142983; AllianceGenome:HGNC:7391 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX7; HYD1; ECTD3; STHAG1 Summary This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 10.8), fat (RPKM 4.4) and 8 other tissues See more Orthologs mouse all