RIC8B, Official Symbol RIC8Bprovided by HGNC Official Full Name RIC8 guanine nucleotide exchange factor Bprovided by HGNC Primary source HGNC:HGNC:25555 See related Ensembl:ENSG00000111785 MIM:609147; AllianceGenome:HGNC:25555 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RIC8; hSyn Summary Enables G-protein alpha-subunit binding activity. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 2.6), gall bladder (RPKM 2.0) and 25 other tissues See more Orthologs mouse all