PDGFRL, Official Symbol PDGFRLprovided by HGNC Official Full Name platelet derived growth factor receptor likeprovided by HGNC Primary source HGNC:HGNC:8805 See related Ensembl:ENSG00000104213 MIM:604584; AllianceGenome:HGNC:8805 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PDGRL; PRLTS Summary This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008] Expression Broad expression in fat (RPKM 15.7), ovary (RPKM 15.2) and 16 other tissues See more Orthologs mouse all