KLK1, Official Symbol KLK1provided by HGNC Official Full Name kallikrein 1provided by HGNC Primary source HGNC:HGNC:6357 See related Ensembl:ENSG00000167748 MIM:147910; AllianceGenome:HGNC:6357 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hK1; KLKR; Klk6 Summary Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008] Expression Biased expression in salivary gland (RPKM 569.2) and pancreas (RPKM 508.7) See more Orthologs mouse all