GABRP, Official Symbol GABRPprovided by HGNC Official Full Name gamma-aminobutyric acid type A receptor subunit piprovided by HGNC Primary source HGNC:HGNC:4089 See related Ensembl:ENSG00000094755 MIM:602729; AllianceGenome:HGNC:4089 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] Expression Biased expression in esophagus (RPKM 45.1), endometrium (RPKM 30.6) and 5 other tissues See more Orthologs mouse all