ICMT, Official Symbol ICMTprovided by HGNC Official Full Name isoprenylcysteine carboxyl methyltransferaseprovided by HGNC Primary source HGNC:HGNC:5350 See related Ensembl:ENSG00000116237 MIM:605851; AllianceGenome:HGNC:5350 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCMT; PPMT; PCCMT; HSTE14; MST098; MSTP098 Summary This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 21.7), placenta (RPKM 18.3) and 25 other tissues See more Orthologs mouse all