ERCC4, Official Symbol ERCC4provided by HGNC Official Full Name ERCC excision repair 4, endonuclease catalytic subunitprovided by HGNC Primary source HGNC:HGNC:3436 See related Ensembl:ENSG00000175595 MIM:133520; AllianceGenome:HGNC:3436 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as XPF; RAD1; FANCQ; XFEPS; ERCC11 Summary The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009] Expression Ubiquitous expression in testis (RPKM 4.4), thyroid (RPKM 2.5) and 25 other tissues See more Orthologs mouse all