TPD52L1, Official Symbol TPD52L1provided by HGNC Official Full Name TPD52 like 1provided by HGNC Primary source HGNC:HGNC:12006 See related Ensembl:ENSG00000111907 MIM:604069; AllianceGenome:HGNC:12006 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as D53; TPD53 Summary This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016] Expression Broad expression in adrenal (RPKM 40.8), salivary gland (RPKM 18.6) and 14 other tissues See more Orthologs mouse all