GGT6, Official Symbol GGT6provided by HGNC Official Full Name gamma-glutamyltransferase 6provided by HGNC Primary source HGNC:HGNC:26891 See related Ensembl:ENSG00000167741 MIM:612341; AllianceGenome:HGNC:26891 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008] Expression Biased expression in colon (RPKM 26.8), kidney (RPKM 22.6) and 12 other tissues See more Orthologs mouse all