SCUBE2, Official Symbol SCUBE2provided by HGNC Official Full Name signal peptide, CUB domain and EGF like domain containing 2provided by HGNC Primary source HGNC:HGNC:30425 See related Ensembl:ENSG00000175356 MIM:611747; AllianceGenome:HGNC:30425 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CEGB1; CEGF1; CEGP1; scube/You Summary Predicted to enable calcium ion binding activity; hedgehog family protein binding activity; and lipid binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within several processes, including positive regulation of chondrocyte proliferation; positive regulation of osteoblast differentiation; and positive regulation of smoothened signaling pathway. Predicted to be located in extracellular region. Predicted to be active in cell surface and extracellular space. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in prostate (RPKM 8.1), urinary bladder (RPKM 7.3) and 20 other tissues See more Orthologs mouse all