EXOC8, Official Symbol EXOC8provided by HGNC Official Full Name exocyst complex component 8provided by HGNC Primary source HGNC:HGNC:24659 See related Ensembl:ENSG00000116903 MIM:615283; AllianceGenome:HGNC:24659 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EXO84; SEC84; Exo84p; NEDMISB Summary This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016] Orthologs mouse all