ITGB2, Official Symbol ITGB2provided by HGNC Official Full Name integrin subunit beta 2provided by HGNC Primary source HGNC:HGNC:6155 See related Ensembl:ENSG00000160255 MIM:600065; AllianceGenome:HGNC:6155 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1 Summary This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Expression Broad expression in bone marrow (RPKM 117.8), appendix (RPKM 80.8) and 14 other tissues See more Orthologs mouse all