TAF1B, Official Symbol TAF1Bprovided by HGNC Official Full Name TATA-box binding protein associated factor, RNA polymerase I subunit Bprovided by HGNC Primary source HGNC:HGNC:11533 See related Ensembl:ENSG00000115750 MIM:604904; AllianceGenome:HGNC:11533 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SL1; RAF1B; RAFI63; TAFI63; MGC:9349 Summary Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in testis (RPKM 5.9), placenta (RPKM 5.4) and 25 other tissues See more Orthologs mouse all