POLR1C, Official Symbol POLR1Cprovided by HGNC Official Full Name RNA polymerase I and III subunit Cprovided by HGNC Primary source HGNC:HGNC:20194 See related Ensembl:ENSG00000171453 MIM:610060; AllianceGenome:HGNC:20194 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AC40; RPA5; TCS3; HLD11; RPA39; RPA40; RPAC1; RPC40 Summary The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Ubiquitous expression in testis (RPKM 7.7), skin (RPKM 5.6) and 25 other tissues See more Orthologs mouse all