GP9, Official Symbol GP9provided by HGNC Official Full Name glycoprotein IX plateletprovided by HGNC Primary source HGNC:HGNC:4444 See related Ensembl:ENSG00000169704 MIM:173515; AllianceGenome:HGNC:4444 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPIX; CD42a Summary This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008] Expression Biased expression in bone marrow (RPKM 1.0), spleen (RPKM 0.7) and 4 other tissues See more Orthologs mouse all