CLDN20, Official Symbol CLDN20provided by HGNC Official Full Name claudin 20provided by HGNC Primary source HGNC:HGNC:2042 See related Ensembl:ENSG00000171217 AllianceGenome:HGNC:2042 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. [provided by RefSeq, Jun 2010] Expression Low expression observed in reference dataset See more Orthologs mouse all