CDK7, Official Symbol CDK7provided by HGNC Official Full Name cyclin dependent kinase 7provided by HGNC Primary source HGNC:HGNC:1778 See related Ensembl:ENSG00000134058 MIM:601955; AllianceGenome:HGNC:1778 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAK; CAK1; HCAK; MO15; STK1; CDKN7; p39MO15 Summary The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 18.1), placenta (RPKM 14.9) and 25 other tissues See more Orthologs mouse all