BSN, Official Symbol BSNprovided by HGNC Official Full Name bassoon presynaptic cytomatrix proteinprovided by HGNC Primary source HGNC:HGNC:1117 See related Ensembl:ENSG00000164061 MIM:604020; AllianceGenome:HGNC:1117 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZNF231 Summary Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 13.0), testis (RPKM 2.3) and 1 other tissue See more Orthologs mouse all