CSNK2B, Official Symbol CSNK2Bprovided by HGNC Official Full Name casein kinase 2 betaprovided by HGNC Primary source HGNC:HGNC:2460 See related Ensembl:ENSG00000204435 MIM:115441; AllianceGenome:HGNC:2460 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as G5A; CK2B; CK2N; Ckb1; Ckb2; CSK2B; POBINDS Summary This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Expression Ubiquitous expression in testis (RPKM 91.5), skin (RPKM 69.4) and 25 other tissues See more Orthologs mouse all