SLC5A12, Official Symbol SLC5A12provided by HGNC Official Full Name solute carrier family 5 member 12provided by HGNC Primary source HGNC:HGNC:28750 See related Ensembl:ENSG00000148942 MIM:612455; AllianceGenome:HGNC:28750 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SMCT2 Summary Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).[supplied by OMIM, Dec 2008] Expression Restricted expression toward kidney (RPKM 72.2) See more Orthologs mouse all