NPFF, Official Symbol NPFFprovided by HGNC Official Full Name neuropeptide FF-amide peptide precursorprovided by HGNC Primary source HGNC:HGNC:7901 See related Ensembl:ENSG00000139574 MIM:604643; AllianceGenome:HGNC:7901 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FMRFAL Summary This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] Expression Ubiquitous expression in skin (RPKM 3.8), spleen (RPKM 2.1) and 24 other tissues See more Orthologs mouse all