CYP2D7, Official Symbol CYP2D7provided by HGNC Official Full Name cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)provided by HGNC Primary source HGNC:HGNC:2624 See related AllianceGenome:HGNC:2624 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CYP2D; CYP2D6; CYP2D@; CYP2D7P; P450C2D; P450DB1; CYP2D7AP; CYP2D7P1; RNA40057 Summary This gene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is a segregating pseudogene, where some individuals may have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. In this case, the functional allele is thought to be rare. This locus is part of a cluster of cytochrome P450 genes on chromosome 22. [provided by RefSeq, Jan 2017] Annotation information Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene. Expression Broad expression in liver (RPKM 9.7), small intestine (RPKM 3.1) and 14 other tissues See more Orthologs all