FNIP1, Official Symbol FNIP1provided by HGNC Official Full Name folliculin interacting protein 1provided by HGNC Primary source HGNC:HGNC:29418 See related Ensembl:ENSG00000217128 MIM:610594; AllianceGenome:HGNC:29418 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IMD93 Summary This gene encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017] Expression Ubiquitous expression in testis (RPKM 9.3), thyroid (RPKM 7.7) and 25 other tissues See more Orthologs mouse all