VARS2, Official Symbol VARS2provided by HGNC Official Full Name valyl-tRNA synthetase 2, mitochondrialprovided by HGNC Primary source HGNC:HGNC:21642 See related Ensembl:ENSG00000137411 MIM:612802; AllianceGenome:HGNC:21642 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VALRS; VARSL; VARS2L; COXPD20 Summary This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2014] Expression Ubiquitous expression in brain (RPKM 7.4), esophagus (RPKM 6.1) and 25 other tissues See more Orthologs mouse all