SYNE3, Official Symbol SYNE3provided by HGNC Official Full Name spectrin repeat containing nuclear envelope family member 3provided by HGNC Primary source HGNC:HGNC:19861 See related Ensembl:ENSG00000176438 MIM:610861; AllianceGenome:HGNC:19861 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341 Summary Enables actin filament binding activity and cytoskeleton-nuclear membrane anchor activity. Involved in cytoskeleton organization; establishment of protein localization to membrane; and regulation of cell shape. Located in nuclear membrane. Part of meiotic nuclear membrane microtubule tethering complex. Biomarker of Huntington's disease. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 4.3), bone marrow (RPKM 3.9) and 24 other tissues See more Orthologs mouse all