HNRNPLL, Official Symbol HNRNPLLprovided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein L likeprovided by HGNC Primary source HGNC:HGNC:25127 See related Ensembl:ENSG00000143889 MIM:611208; AllianceGenome:HGNC:25127 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SRRF; HNRPLL Summary HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008] Expression Ubiquitous expression in testis (RPKM 17.8), thyroid (RPKM 11.5) and 25 other tissues See more Orthologs mouse all