EEF2K, Official Symbol EEF2Kprovided by HGNC Official Full Name eukaryotic elongation factor 2 kinaseprovided by HGNC Primary source HGNC:HGNC:24615 See related Ensembl:ENSG00000103319 MIM:606968; AllianceGenome:HGNC:24615 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as eEF-2K; CaMKIII; HSU93850 Summary This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in skin (RPKM 21.4), fat (RPKM 10.0) and 24 other tissues See more Orthologs mouse all