PDYN, Official Symbol PDYNprovided by HGNC Official Full Name prodynorphinprovided by HGNC Primary source HGNC:HGNC:8820 See related Ensembl:ENSG00000101327 MIM:131340; AllianceGenome:HGNC:8820 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADCA; PENKB; SCA23 Summary The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010] Expression Restricted expression toward brain (RPKM 14.6) See more Orthologs mouse all