TCHH, Official Symbol TCHHprovided by HGNC Official Full Name trichohyalinprovided by HGNC Primary source HGNC:HGNC:11791 See related Ensembl:ENSG00000159450 MIM:190370; AllianceGenome:HGNC:11791 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as THH; THL; TRHY; UHS3 Summary The protein encoded by this gene forms crosslinked complexes with itself and keratin intermediate filaments to provide mechanical strength to the hair follicle inner root sheath. The encoded protein also is important for structural integrity of the filiform papillae of the tongue. Defects in this gene are a cause of uncombable hair syndrome. [provided by RefSeq, Feb 2017] Expression Biased expression in placenta (RPKM 1.2), spleen (RPKM 1.1) and 13 other tissues See more Orthologs mouse all