HOXA1, Official Symbol HOXA1provided by HGNC Official Full Name homeobox A1provided by HGNC Primary source HGNC:HGNC:5099 See related Ensembl:ENSG00000105991 MIM:142955; AllianceGenome:HGNC:5099 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BSAS; HOX1; HOX1F Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region. [provided by RefSeq, Jul 2008] Expression Biased expression in urinary bladder (RPKM 4.0), skin (RPKM 1.0) and 13 other tissues See more Orthologs mouse all