TRIM16, Official Symbol TRIM16provided by HGNC Official Full Name tripartite motif containing 16provided by HGNC Primary source HGNC:HGNC:17241 See related Ensembl:ENSG00000221926 MIM:609505; AllianceGenome:HGNC:17241 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EBBP Summary The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy. [provided by RefSeq, Jan 2017] Expression Broad expression in esophagus (RPKM 47.9), placenta (RPKM 17.3) and 19 other tissues See more Orthologs mouse all