ADM, Official Symbol ADMprovided by HGNC Official Full Name adrenomedullinprovided by HGNC Primary source HGNC:HGNC:259 See related Ensembl:ENSG00000148926 MIM:103275; AllianceGenome:HGNC:259 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AM; PAMP Summary The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014] Expression Broad expression in placenta (RPKM 66.2), fat (RPKM 27.8) and 18 other tissues See more Orthologs mouse all