OASL, Official Symbol OASLprovided by HGNC Official Full Name 2'-5'-oligoadenylate synthetase likeprovided by HGNC Primary source HGNC:HGNC:8090 See related Ensembl:ENSG00000135114 MIM:603281; AllianceGenome:HGNC:8090 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OASL1; OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL Summary Enables DNA binding activity and double-stranded RNA binding activity. Involved in several processes, including interleukin-27-mediated signaling pathway; negative regulation of viral genome replication; and positive regulation of RIG-I signaling pathway. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in bone marrow (RPKM 19.8), stomach (RPKM 11.1) and 13 other tissues See more Orthologs all