MARCO, Official Symbol MARCOprovided by HGNC Official Full Name macrophage receptor with collagenous structureprovided by HGNC Primary source HGNC:HGNC:6895 See related Ensembl:ENSG00000019169 MIM:604870; AllianceGenome:HGNC:6895 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SR-A6; SCARA2 Summary The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008] Expression Biased expression in lung (RPKM 74.5), appendix (RPKM 41.8) and 3 other tissues See more Orthologs mouse all