DYNC2I1, Official Symbol DYNC2I1provided by HGNC Official Full Name dynein 2 intermediate chain 1provided by HGNC Primary source HGNC:HGNC:21862 See related Ensembl:ENSG00000126870 MIM:615462; AllianceGenome:HGNC:21862 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DIC6; SRPS6; SRTD8; WDR60; FAP163; CFAP163 Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) and may facilitate the formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein contains four WD repeats and may play a role in the formation of cilia. Mutations in this gene have been associated with short-rib polydactyly and Jeune syndromes. [provided by RefSeq, Mar 2014] Expression Broad expression in testis (RPKM 15.3), fat (RPKM 3.5) and 21 other tissues See more Orthologs mouse all