TRHR, Official Symbol TRHRprovided by HGNC Official Full Name thyrotropin releasing hormone receptorprovided by HGNC Primary source HGNC:HGNC:12299 See related Ensembl:ENSG00000174417 MIM:188545; AllianceGenome:HGNC:12299 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHNG7; TRH-R Summary This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011] Expression Low expression observed in reference dataset See more Orthologs mouse all