LYZ, Official Symbol LYZprovided by HGNC Official Full Name lysozymeprovided by HGNC Primary source HGNC:HGNC:6740 See related Ensembl:ENSG00000090382 MIM:153450; AllianceGenome:HGNC:6740 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LZM; LYZF1 Summary This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014] Expression Biased expression in stomach (RPKM 5710.8), salivary gland (RPKM 4398.2) and 8 other tissues See more Orthologs all