NCOA4, Official Symbol NCOA4provided by HGNC Official Full Name nuclear receptor coactivator 4provided by HGNC Primary source HGNC:HGNC:7671 See related Ensembl:ENSG00000266412 MIM:601984; AllianceGenome:HGNC:7671 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RFG; ELE1; PTC3; ARA70 Summary This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. [provided by RefSeq, Feb 2009] Expression Ubiquitous expression in duodenum (RPKM 113.8), liver (RPKM 75.2) and 25 other tissues See more Orthologs mouse all