TRMT6, Official Symbol TRMT6provided by HGNC Official Full Name tRNA methyltransferase 6 non-catalytic subunitprovided by HGNC Primary source HGNC:HGNC:20900 See related Ensembl:ENSG00000089195 AllianceGenome:HGNC:20900 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GCD10; CGI-09; Gcd10p Summary This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Ubiquitous expression in testis (RPKM 9.9), bone marrow (RPKM 9.2) and 25 other tissues See more Orthologs mouse all