PLCH1, Official Symbol PLCH1provided by HGNC Official Full Name phospholipase C eta 1provided by HGNC Primary source HGNC:HGNC:29185 See related Ensembl:ENSG00000114805 MIM:612835; AllianceGenome:HGNC:29185 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPE14; PLCL3; PLC-L3; PLC eta 1 Summary PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM, Jun 2009] Expression Biased expression in testis (RPKM 4.0), thyroid (RPKM 1.7) and 9 other tissues See more Orthologs mouse all