ADGRE1, Official Symbol ADGRE1provided by HGNC Official Full Name adhesion G protein-coupled receptor E1provided by HGNC Primary source HGNC:HGNC:3336 See related Ensembl:ENSG00000174837 MIM:600493; AllianceGenome:HGNC:3336 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EMR1; TM7LN3 Summary This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Expression Biased expression in spleen (RPKM 6.8), appendix (RPKM 4.1) and 12 other tissues See more Orthologs mouse all