GAB1, Official Symbol GAB1provided by HGNC Official Full Name GRB2 associated binding protein 1provided by HGNC Primary source HGNC:HGNC:4066 See related Ensembl:ENSG00000109458 MIM:604439; AllianceGenome:HGNC:4066 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNB26 Summary The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] Expression Ubiquitous expression in brain (RPKM 3.3), lung (RPKM 3.0) and 25 other tissues See more Orthologs mouse all