AMD1, Official Symbol AMD1provided by HGNC Official Full Name adenosylmethionine decarboxylase 1provided by HGNC Primary source HGNC:HGNC:457 See related Ensembl:ENSG00000123505 MIM:180980; AllianceGenome:HGNC:457 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AMD; SAMDC; ADOMETDC Summary This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013] Expression Ubiquitous expression in prostate (RPKM 106.1), bone marrow (RPKM 38.6) and 25 other tissues See more Orthologs mouse all