GAL3ST1, Official Symbol GAL3ST1provided by HGNC Official Full Name galactose-3-O-sulfotransferase 1provided by HGNC Primary source HGNC:HGNC:24240 See related Ensembl:ENSG00000128242 MIM:602300; AllianceGenome:HGNC:24240 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CST Summary Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. This gene encodes galactosylceramide sulfotransferase, which catalyzes the sulfation of membrane glycolipids including the final step in the synthesis of sulfatide, a major lipid component of the myelin sheath. This gene exhibits elevated expression in ovarian epithelial carcinoma and the encoded enzyme exhibits elevated activity in renal cell carcinoma. Mutations in this gene may be associated with reduced insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] Expression Biased expression in kidney (RPKM 2.0), duodenum (RPKM 1.8) and 9 other tissues See more Orthologs mouse all