DCLRE1A, Official Symbol DCLRE1Aprovided by HGNC Official Full Name DNA cross-link repair 1Aprovided by HGNC Primary source HGNC:HGNC:17660 See related Ensembl:ENSG00000198924 MIM:609682; AllianceGenome:HGNC:17660 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PSO2; SNM1; SNM1A Summary This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] Expression Ubiquitous expression in thyroid (RPKM 3.4), testis (RPKM 3.3) and 25 other tissues See more Orthologs mouse all