KRT1, Official Symbol KRT1provided by HGNC Official Full Name keratin 1provided by HGNC Primary source HGNC:HGNC:6412 See related Ensembl:ENSG00000167768 MIM:139350; AllianceGenome:HGNC:6412 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as K1; CK1; EHK; AEI2; EHK1; EPPK; KRT1A; NEPPK Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008] Expression Restricted expression toward skin (RPKM 6502.3) See more Orthologs mouse all