KLHL8, Official Symbol KLHL8provided by HGNC Official Full Name kelch like family member 8provided by HGNC Primary source HGNC:HGNC:18644 See related Ensembl:ENSG00000145332 MIM:611967; AllianceGenome:HGNC:18644 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Located in nucleoplasm. Part of Cul3-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 11.3), kidney (RPKM 6.2) and 25 other tissues See more Orthologs mouse all