TNNT2, Official Symbol TNNT2provided by HGNC Official Full Name troponin T2, cardiac typeprovided by HGNC Primary source HGNC:HGNC:11949 See related Ensembl:ENSG00000118194 MIM:191045; AllianceGenome:HGNC:11949 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6 Summary This gene encodes the cardiac isoform of troponin T. The encoded protein is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. [provided by RefSeq, May 2022] Expression Restricted expression toward heart (RPKM 1647.3) See more Orthologs mouse all