AIP, Official Symbol AIPprovided by HGNC Official Full Name aryl hydrocarbon receptor interacting proteinprovided by HGNC Primary source HGNC:HGNC:358 See related Ensembl:ENSG00000110711 MIM:605555; AllianceGenome:HGNC:358 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARA9; XAP2; PITA1; XAP-2; FKBP16; FKBP37; SMTPHN Summary The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in lymph node (RPKM 29.1), spleen (RPKM 26.1) and 25 other tissues See more Orthologs mouse all