RNF19B, Official Symbol RNF19Bprovided by HGNC Official Full Name ring finger protein 19Bprovided by HGNC Primary source HGNC:HGNC:26886 See related Ensembl:ENSG00000116514 MIM:610872; AllianceGenome:HGNC:26886 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NKLAM; IBRDC3 Summary This gene encodes a multi-pass membrane protein containing two RING-type and one IBR-type zinc finger motifs. The encoded protin is an E3 ubiquitin-protein ligase that plays a role in the cytotoxic effects of natural killer (NK) cells. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes X and Y in a possible pseudoautosomal region. [provided by RefSeq, Jul 2014] Expression Broad expression in testis (RPKM 31.7), bone marrow (RPKM 15.6) and 23 other tissues See more Orthologs mouse all