GNRHR2, Official Symbol GNRHR2provided by HGNC Official Full Name gonadotropin releasing hormone receptor 2 (pseudogene)provided by HGNC Primary source HGNC:HGNC:16341 See related Ensembl:ENSG00000211451 MIM:612875; AllianceGenome:HGNC:16341 Gene type pseudo RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GnRH-II-R Summary In non-hominoid primates and non-mammalian vertebrates, the gonadotropin releasing hormone 2 receptor gene (GnRHR2) encodes a seven-transmembrane G-protein coupled receptor. However, in human, the corresponding reading frame contains a premature stop codon, which has been suggested to encode a selenocysteine residue, but there is no solid evidence for selenocysteine incorporation (PMID: 12538601). It appears that the human GnRHR2 transcription occurs but the gene does not likely produce a functional multi-transmembrane protein. A non-transcribed pseudogene of GnRHR2 is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2013] Expression Ubiquitous expression in brain (RPKM 13.0), kidney (RPKM 11.5) and 25 other tissues See more