ROM1, Official Symbol ROM1provided by HGNC Official Full Name retinal outer segment membrane protein 1provided by HGNC Primary source HGNC:HGNC:10254 See related Ensembl:ENSG00000149489 MIM:180721; AllianceGenome:HGNC:10254 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ROM; RP7; ROSP1; TSPAN23 Summary This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 5.2), ovary (RPKM 2.2) and 23 other tissues See more Orthologs mouse all