SERPINE2, Official Symbol SERPINE2provided by HGNC Official Full Name serpin family E member 2provided by HGNC Primary source HGNC:HGNC:8951 See related Ensembl:ENSG00000135919 MIM:177010; AllianceGenome:HGNC:8951 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GDN; PI7; PN1; PNI; PI-7; PN-1; GDNPF Summary This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] Expression Biased expression in placenta (RPKM 298.6), brain (RPKM 61.2) and 6 other tissues See more Orthologs mouse all