HOOK3, Official Symbol HOOK3provided by HGNC Official Full Name hook microtubule tethering protein 3provided by HGNC Primary source HGNC:HGNC:23576 See related Ensembl:ENSG00000168172 MIM:607825; AllianceGenome:HGNC:23576 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HK3 Summary Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004] Expression Ubiquitous expression in thyroid (RPKM 6.6), fat (RPKM 4.5) and 25 other tissues See more Orthologs mouse all