MRPL23, Official Symbol MRPL23provided by HGNC Official Full Name mitochondrial ribosomal protein L23provided by HGNC Primary source HGNC:HGNC:10322 See related Ensembl:ENSG00000214026 Ensembl:ENSG00000276345 MIM:600789; AllianceGenome:HGNC:10322 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RPL23; uL23m; L23MRP; RPL23L Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in ovary (RPKM 5.6), skin (RPKM 5.4) and 25 other tissues See more Orthologs mouse all