TSHR, Official Symbol TSHRprovided by HGNC Official Full Name thyroid stimulating hormone receptorprovided by HGNC Primary source HGNC:HGNC:12373 See related Ensembl:ENSG00000165409 MIM:603372; AllianceGenome:HGNC:12373 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LGR3; CHNG1; hTSHR-I Summary The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] Expression Restricted expression toward thyroid (RPKM 104.1) See more Orthologs mouse all