CD40LG, Official Symbol CD40LGprovided by HGNC Official Full Name CD40 ligandprovided by HGNC Primary source HGNC:HGNC:11935 See related Ensembl:ENSG00000102245 MIM:300386; AllianceGenome:HGNC:11935 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L Summary The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008] Expression Biased expression in lymph node (RPKM 7.7), appendix (RPKM 4.4) and 10 other tissues See more Orthologs mouse all