MNT, Official Symbol MNTprovided by HGNC Official Full Name MAX network transcriptional repressorprovided by HGNC Primary source HGNC:HGNC:7188 See related Ensembl:ENSG00000070444 MIM:603039; AllianceGenome:HGNC:7188 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ROX; MAD6; MXD6; bHLHd3; lncRNA-HAL Summary The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in testis (RPKM 4.9), bone marrow (RPKM 4.7) and 25 other tissues See more Orthologs mouse all