ITGA10, Official Symbol ITGA10provided by HGNC Official Full Name integrin subunit alpha 10provided by HGNC Primary source HGNC:HGNC:6135 See related Ensembl:ENSG00000143127 MIM:604042; AllianceGenome:HGNC:6135 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRO827 Summary Integrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell-surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP-2epsilon and Ets-1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Expression Broad expression in lung (RPKM 2.4), heart (RPKM 1.3) and 22 other tissues See more Orthologs mouse all