NPSR1, Official Symbol NPSR1provided by HGNC Official Full Name neuropeptide S receptor 1provided by HGNC Primary source HGNC:HGNC:23631 See related Ensembl:ENSG00000187258 MIM:608595; AllianceGenome:HGNC:23631 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GPRA; NPSR; VRR1; ASRT2; PGR14; GPR154 Summary This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Low expression observed in reference dataset See more Orthologs mouse all