NOMO1, Official Symbol NOMO1provided by HGNC Official Full Name NODAL modulator 1provided by HGNC Primary source HGNC:HGNC:30060 See related Ensembl:ENSG00000103512 MIM:609157; AllianceGenome:HGNC:30060 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PM5; Nomo Summary This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in brain (RPKM 58.5), heart (RPKM 50.3) and 25 other tissues See more Orthologs all