CNOT8, Official Symbol CNOT8provided by HGNC Official Full Name CCR4-NOT transcription complex subunit 8provided by HGNC Primary source HGNC:HGNC:9207 See related Ensembl:ENSG00000155508 MIM:603731; AllianceGenome:HGNC:9207 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAF1; POP2; CALIF; Caf1b; hCAF1 Summary Enables poly(A)-specific ribonuclease activity. Involved in exonucleolytic catabolism of deadenylated mRNA and positive regulation of cell population proliferation. Located in nucleus. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 22.1), lymph node (RPKM 19.7) and 25 other tissues See more Orthologs mouse all