NACC2, Official Symbol NACC2provided by HGNC Official Full Name NACC family member 2provided by HGNC Primary source HGNC:HGNC:23846 See related Ensembl:ENSG00000148411 MIM:615786; AllianceGenome:HGNC:23846 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RBB; BEND9; NAC-2; BTBD14; BTBD31; BTBD14A Summary Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and protein homooligomerization. Located in chromatin; mitochondrion; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 17.8), fat (RPKM 7.6) and 24 other tissues See more Orthologs mouse all