GSDMB, Official Symbol GSDMBprovided by HGNC Official Full Name gasdermin Bprovided by HGNC Primary source HGNC:HGNC:23690 See related Ensembl:ENSG00000073605 MIM:611221; AllianceGenome:HGNC:23690 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GSDML; PP4052; GSDMB-1; PRO2521 Summary This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016] Expression Broad expression in small intestine (RPKM 18.8), duodenum (RPKM 16.9) and 17 other tissues See more Orthologs all