HPDL, Official Symbol HPDLprovided by HGNC Official Full Name 4-hydroxyphenylpyruvate dioxygenase likeprovided by HGNC Primary source HGNC:HGNC:28242 See related Ensembl:ENSG00000186603 MIM:618994; AllianceGenome:HGNC:28242 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SPG83; GLOXD1; NEDSWMA; 4-HPPD-L Summary The protein encoded by this intronless gene localizes to mitochondria, where it may function as 4-hydroxyphenylpyruvate dioxygenase. Clinical studies have identified several bi-allelic variants in this gene that lower the level of the encoded protein and lead to a clinically variable form of pediatric-onset spastic movement disorder. [provided by RefSeq, Aug 2020] Orthologs mouse all