SPIRE1, Official Symbol SPIRE1provided by HGNC Official Full Name spire type actin nucleation factor 1provided by HGNC Primary source HGNC:HGNC:30622 See related Ensembl:ENSG00000134278 MIM:609216; AllianceGenome:HGNC:30622 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Spir-1 Summary Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM, Mar 2008] Expression Broad expression in brain (RPKM 20.7), testis (RPKM 14.2) and 22 other tissues See more Orthologs mouse all