CHRNA5, Official Symbol CHRNA5provided by HGNC Official Full Name cholinergic receptor nicotinic alpha 5 subunitprovided by HGNC Primary source HGNC:HGNC:1959 See related Ensembl:ENSG00000169684 MIM:118505; AllianceGenome:HGNC:1959 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LNCR2 Summary The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010] Expression Broad expression in gall bladder (RPKM 1.4), colon (RPKM 1.2) and 19 other tissues See more Orthologs mouse all