PTHLH, Official Symbol PTHLHprovided by HGNC Official Full Name parathyroid hormone like hormoneprovided by HGNC Primary source HGNC:HGNC:9607 See related Ensembl:ENSG00000087494 MIM:168470; AllianceGenome:HGNC:9607 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HHM; PLP; BDE2; PTHR; PTHRP Summary The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013] Expression Broad expression in esophagus (RPKM 1.7), endometrium (RPKM 1.5) and 19 other tissues See more Orthologs mouse all