SLC8A2, Official Symbol SLC8A2provided by HGNC Official Full Name solute carrier family 8 member A2provided by HGNC Primary source HGNC:HGNC:11069 See related Ensembl:ENSG00000118160 MIM:601901; AllianceGenome:HGNC:11069 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NCX2 Summary Predicted to enable calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium:sodium antiporter activity. Predicted to be involved in several processes, including inorganic cation transmembrane transport; learning or memory; and regulation of short-term neuronal synaptic plasticity. Predicted to act upstream of or within several processes, including modulation of chemical synaptic transmission; regulation of action potential firing pattern; and response to ischemia. Part of presynapse. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in brain (RPKM 19.6), endometrium (RPKM 1.5) and 1 other tissue See more Orthologs mouse all