DOCK10, Official Symbol DOCK10provided by HGNC Official Full Name dedicator of cytokinesis 10provided by HGNC Primary source HGNC:HGNC:23479 See related Ensembl:ENSG00000135905 MIM:611518; AllianceGenome:HGNC:23479 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZIZ3; DRIP2; Nbla10300 Summary This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014] Expression Broad expression in spleen (RPKM 10.3), lymph node (RPKM 9.4) and 22 other tissues See more Orthologs mouse all