CDC42EP2, Official Symbol CDC42EP2provided by HGNC Official Full Name CDC42 effector protein 2provided by HGNC Primary source HGNC:HGNC:16263 See related Ensembl:ENSG00000149798 MIM:606132; AllianceGenome:HGNC:16263 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CEP2; BORG1 Summary CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in fat (RPKM 13.9), gall bladder (RPKM 10.2) and 23 other tissues See more Orthologs mouse all