DSG4, Official Symbol DSG4provided by HGNC Official Full Name desmoglein 4provided by HGNC Primary source HGNC:HGNC:21307 See related Ensembl:ENSG00000175065 MIM:607892; AllianceGenome:HGNC:21307 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LAH; HYPT6; CDGF13; CDHF13 Summary This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016] Expression Low expression observed in reference dataset See more Orthologs mouse all