GTF2H5, Official Symbol GTF2H5provided by HGNC Official Full Name general transcription factor IIH subunit 5provided by HGNC Primary source HGNC:HGNC:21157 See related Ensembl:ENSG00000272047 MIM:608780; AllianceGenome:HGNC:21157 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTD; TFB5; TTD3; TTDA; TFIIH; TTD-A; TGF2H5; C6orf175; bA120J8.2 Summary This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq, Mar 2009] Expression Ubiquitous expression in brain (RPKM 4.4), fat (RPKM 3.8) and 25 other tissues See more Orthologs mouse all