MARCHF9, Official Symbol MARCHF9provided by HGNC Official Full Name membrane associated ring-CH-type finger 9provided by HGNC Primary source HGNC:HGNC:25139 See related Ensembl:ENSG00000139266 MIM:613336; AllianceGenome:HGNC:25139 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MARCH9; RNF179; MARCH-IX Summary MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).[supplied by OMIM, Apr 2010] Expression Ubiquitous expression in kidney (RPKM 5.4), spleen (RPKM 4.4) and 25 other tissues See more Orthologs mouse all