UBE2E1, Official Symbol UBE2E1provided by HGNC Official Full Name ubiquitin conjugating enzyme E2 E1provided by HGNC Primary source HGNC:HGNC:12477 See related Ensembl:ENSG00000170142 MIM:602916; AllianceGenome:HGNC:12477 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBCH6 Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011] Expression Ubiquitous expression in lymph node (RPKM 26.5), brain (RPKM 25.3) and 25 other tissues See more Orthologs all