SNRNP70, Official Symbol SNRNP70provided by HGNC Official Full Name small nuclear ribonucleoprotein U1 subunit 70provided by HGNC Primary source HGNC:HGNC:11150 See related Ensembl:ENSG00000104852 MIM:180740; AllianceGenome:HGNC:11150 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RPU1; Snp1; U1AP; U170K; U1RNP; RNPU1Z; SNRP70; U1-70K Summary Enables U1 snRNA binding activity. Involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Located in nucleoplasm. Part of U1 snRNP and spliceosomal complex. Implicated in disease of mental health and systemic lupus erythematosus. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in prostate (RPKM 63.5), spleen (RPKM 63.2) and 25 other tissues See more Orthologs mouse all