DYNLT2B, Official Symbol DYNLT2Bprovided by HGNC Official Full Name dynein light chain Tctex-type 2Bprovided by HGNC Primary source HGNC:HGNC:28482 See related Ensembl:ENSG00000213123 MIM:617353; AllianceGenome:HGNC:28482 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SRTD17; TCTEX1D2 Summary Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains. This gene encodes a subunit of the human cytoplasmic dynein-2 complex. Mutations in this gene are associated with short-rib thoracic dysplasia 17 with or without polydactyly. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017] Expression Broad expression in testis (RPKM 12.7), brain (RPKM 6.1) and 23 other tissues See more Orthologs mouse all