MYB, Official Symbol MYBprovided by HGNC Official Full Name MYB proto-oncogene, transcription factorprovided by HGNC Primary source HGNC:HGNC:7545 See related Ensembl:ENSG00000118513 MIM:189990; AllianceGenome:HGNC:7545 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as efg; Cmyb; c-myb; c-myb_CDS Summary This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Expression Biased expression in bone marrow (RPKM 21.6), colon (RPKM 12.6) and 7 other tissues See more Orthologs mouse all