ICOS, Official Symbol ICOSprovided by HGNC Official Full Name inducible T cell costimulatorprovided by HGNC Primary source HGNC:HGNC:5351 See related Ensembl:ENSG00000163600 MIM:604558; AllianceGenome:HGNC:5351 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AILIM; CD278; CVID1 Summary The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008] Expression Biased expression in lymph node (RPKM 7.8), bone marrow (RPKM 6.5) and 9 other tissues See more Orthologs mouse all