OGDHL, Official Symbol OGDHLprovided by HGNC Official Full Name oxoglutarate dehydrogenase Lprovided by HGNC Primary source HGNC:HGNC:25590 See related Ensembl:ENSG00000197444 MIM:617513; AllianceGenome:HGNC:25590 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YOBELN Summary The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells. [provided by RefSeq, Dec 2016] Expression Biased expression in kidney (RPKM 82.8), liver (RPKM 20.1) and 3 other tissues See more Orthologs mouse all