IHH, Official Symbol IHHprovided by HGNC Official Full Name Indian hedgehog signaling moleculeprovided by HGNC Primary source HGNC:HGNC:5956 See related Ensembl:ENSG00000163501 MIM:600726; AllianceGenome:HGNC:5956 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BDA1; HHG2 Summary This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015] Expression Biased expression in endometrium (RPKM 15.6), colon (RPKM 13.1) and 7 other tissues See more Orthologs mouse all