CTSE, Official Symbol CTSEprovided by HGNC Official Full Name cathepsin Eprovided by HGNC Primary source HGNC:HGNC:2530 See related Ensembl:ENSG00000196188 MIM:116890; AllianceGenome:HGNC:2530 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CATE Summary This gene encodes a member of the A1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme, an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration. [provided by RefSeq, Nov 2015] Expression Biased expression in stomach (RPKM 543.0) and duodenum (RPKM 112.5) See more Orthologs mouse all