SPG11, Official Symbol SPG11provided by HGNC Official Full Name SPG11 vesicle trafficking associated, spatacsinprovided by HGNC Primary source HGNC:HGNC:11226 See related Ensembl:ENSG00000104133 MIM:610844; AllianceGenome:HGNC:11226 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALS5; CMT2X; KIAA1840 Summary The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Expression Ubiquitous expression in thyroid (RPKM 18.4), testis (RPKM 13.2) and 25 other tissues See more Orthologs mouse all