PIGG, Official Symbol PIGGprovided by HGNC Official Full Name phosphatidylinositol glycan anchor biosynthesis class Gprovided by HGNC Primary source HGNC:HGNC:25985 See related Ensembl:ENSG00000174227 MIM:616918; AllianceGenome:HGNC:25985 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EMM; GPI7; LAS21; MRT53; NEDHSCA; PRO4405; RLGS1930 Summary This gene encodes an enzyme involved in glycosylphosphatidylinositol-anchor biosynthesis. The encoded protein, which is localized to the endoplasmic reticulum, is involved in transferring ethanoloamine phosphate to mannose 2 of glycosylphosphatidylinositol species H7 to form species H8. Allelic variants of this gene have been associated with intellectual disability, hypotonia, and early-onset seizures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] Expression Ubiquitous expression in skin (RPKM 5.1), thyroid (RPKM 4.0) and 25 other tissues See more Orthologs mouse all