NUCKS1, Official Symbol NUCKS1provided by HGNC Official Full Name nuclear casein kinase and cyclin dependent kinase substrate 1provided by HGNC Primary source HGNC:HGNC:29923 See related Ensembl:ENSG00000069275 MIM:611912; AllianceGenome:HGNC:29923 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as JC7; NUCKS Summary This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010] Expression Ubiquitous expression in brain (RPKM 77.7), thyroid (RPKM 69.9) and 25 other tissues See more Orthologs mouse all