SERPINF1, Official Symbol SERPINF1provided by HGNC Official Full Name serpin family F member 1provided by HGNC Primary source HGNC:HGNC:8824 See related Ensembl:ENSG00000132386 MIM:172860; AllianceGenome:HGNC:8824 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OI6; OI12; PEDF; EPC-1; PIG35 Summary This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016] Expression Broad expression in liver (RPKM 299.4), gall bladder (RPKM 273.5) and 21 other tissues See more Orthologs mouse all