GRAMD2A, Official Symbol GRAMD2Aprovided by HGNC Official Full Name GRAM domain containing 2Aprovided by HGNC Primary source HGNC:HGNC:27287 See related Ensembl:ENSG00000175318 MIM:620181; AllianceGenome:HGNC:27287 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GRAMD2 Summary Enables phosphatidylinositol-4,5-bisphosphate binding activity. Involved in endoplasmic reticulum-plasma membrane tethering and regulation of store-operated calcium entry. Located in organelle membrane contact site. Is extrinsic component of cytoplasmic side of plasma membrane and intrinsic component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in placenta (RPKM 18.3), lung (RPKM 8.8) and 4 other tissues See more Orthologs mouse all