DEFB1, Official Symbol DEFB1provided by HGNC Official Full Name defensin beta 1provided by HGNC Primary source HGNC:HGNC:2766 See related Ensembl:ENSG00000164825 MIM:602056; AllianceGenome:HGNC:2766 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BD1; HBD1; DEFB-1; DEFB101 Summary Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008] Expression Biased expression in kidney (RPKM 464.8), salivary gland (RPKM 76.4) and 2 other tissues See more Orthologs all