NOSTRIN, Official Symbol NOSTRINprovided by HGNC Official Full Name nitric oxide synthase traffickingprovided by HGNC Primary source HGNC:HGNC:20203 See related Ensembl:ENSG00000163072 MIM:607496; AllianceGenome:HGNC:20203 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DaIP2 Summary Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004] Expression Ubiquitous expression in fat (RPKM 8.2), lung (RPKM 6.6) and 24 other tissues See more Orthologs mouse all