CLCN2, Official Symbol CLCN2provided by HGNC Official Full Name chloride voltage-gated channel 2provided by HGNC Primary source HGNC:HGNC:2020 See related Ensembl:ENSG00000114859 MIM:600570; AllianceGenome:HGNC:2020 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLC2; ECA2; ECA3; EGI3; EGMA; EJM6; EJM8; FHA2; FHII; CIC-2; EGI11; HALD2; LKPAT; clC-2 Summary This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] Expression Broad expression in testis (RPKM 8.7), colon (RPKM 7.2) and 24 other tissues See more Orthologs mouse all