UBE2W, Official Symbol UBE2Wprovided by HGNC Official Full Name ubiquitin conjugating enzyme E2 Wprovided by HGNC Primary source HGNC:HGNC:25616 See related Ensembl:ENSG00000104343 MIM:614277; AllianceGenome:HGNC:25616 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as UBC16; UBC-16 Summary This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] Expression Ubiquitous expression in brain (RPKM 6.0), thyroid (RPKM 4.9) and 25 other tissues See more Orthologs mouse all