KCTD6, Official Symbol KCTD6provided by HGNC Official Full Name potassium channel tetramerization domain containing 6provided by HGNC Primary source HGNC:HGNC:22235 See related Ensembl:ENSG00000168301 MIM:618791; AllianceGenome:HGNC:22235 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KCASH3 Summary Enables ankyrin binding activity; cullin family protein binding activity; and identical protein binding activity. Involved in negative regulation of smoothened signaling pathway and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 6.8), endometrium (RPKM 3.6) and 25 other tissues See more Orthologs mouse all