COX14, Official Symbol COX14provided by HGNC Official Full Name cytochrome c oxidase assembly factor COX14provided by HGNC Primary source HGNC:HGNC:28216 See related Ensembl:ENSG00000178449 MIM:614478; AllianceGenome:HGNC:28216 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCAG1; MC4DN10; C12orf62 Summary This gene encodes a small single-pass transmembrane protein that localizes to mitochondria. This protein may play a role in coordinating the early steps of cytochrome c oxidase (COX; also known as complex IV) subunit assembly and, in particular, the synthesis and assembly of the COX I subunit of the holoenzyme. Mutations in this gene have been associated with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] Expression Ubiquitous expression in fat (RPKM 29.8), heart (RPKM 27.0) and 25 other tissues See more Orthologs mouse all