ARL3, Official Symbol ARL3provided by HGNC Official Full Name ADP ribosylation factor like GTPase 3provided by HGNC Primary source HGNC:HGNC:694 See related Ensembl:ENSG00000138175 MIM:604695; AllianceGenome:HGNC:694 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RP83; ARFL3; JBTS35 Summary Enables GDP binding activity; GTP binding activity; and microtubule binding activity. Involved in several processes, including cilium assembly; protein localization to cilium; and small GTPase mediated signal transduction. Acts upstream of or within post-Golgi vesicle-mediated transport. Located in several cellular components, including microtubule cytoskeleton; midbody; and photoreceptor connecting cilium. Implicated in Joubert syndrome and retinitis pigmentosa 83. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in brain (RPKM 13.2), kidney (RPKM 7.9) and 24 other tissues See more Orthologs mouse all