BPIFA1, Official Symbol BPIFA1provided by HGNC Official Full Name BPI fold containing family A member 1provided by HGNC Primary source HGNC:HGNC:15749 See related Ensembl:ENSG00000198183 MIM:607412; AllianceGenome:HGNC:15749 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LUNX; NASG; PLUNC; SPURT; SPLUNC1; bA49G10.5 Summary This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014] Expression Biased expression in lung (RPKM 1.2), urinary bladder (RPKM 0.9) and 2 other tissues See more Orthologs mouse all