ADAM2, Official Symbol ADAM2provided by HGNC Official Full Name ADAM metallopeptidase domain 2provided by HGNC Primary source HGNC:HGNC:198 See related Ensembl:ENSG00000104755 MIM:601533; AllianceGenome:HGNC:198 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CT15; FTNB; PH30; CRYN1; CRYN2; PH-30b; PH30-beta Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] Expression Restricted expression toward testis (RPKM 28.4) See more Orthologs mouse all