RAPSN, Official Symbol RAPSNprovided by HGNC Official Full Name receptor associated protein of the synapseprovided by HGNC Primary source HGNC:HGNC:9863 See related Ensembl:ENSG00000165917 MIM:601592; AllianceGenome:HGNC:9863 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FADS; CMS11; CMS4C; FADS2; RAPSYN; RNF205 Summary This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011] Expression Biased expression in placenta (RPKM 1.3), prostate (RPKM 0.9) and 7 other tissues See more Orthologs mouse all