GALNT9, Official Symbol GALNT9provided by HGNC Official Full Name polypeptide N-acetylgalactosaminyltransferase 9provided by HGNC Primary source HGNC:HGNC:4131 See related Ensembl:ENSG00000182870 MIM:606251; AllianceGenome:HGNC:4131 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GALNACT9; GALNAC-T9 Summary This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. This gene is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Annotation information Annotation category: suggests misassembly Expression Biased expression in brain (RPKM 5.0), thyroid (RPKM 1.4) and 1 other tissue See more Orthologs mouse all