SLC4A11, Official Symbol SLC4A11provided by HGNC Official Full Name solute carrier family 4 member 11provided by HGNC Primary source HGNC:HGNC:16438 See related Ensembl:ENSG00000088836 MIM:610206; AllianceGenome:HGNC:16438 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BTR1; CHED; CDPD1; CHED2; NABC1; dJ794I6.2 Summary This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010] Expression Biased expression in thyroid (RPKM 6.2), kidney (RPKM 5.1) and 12 other tissues See more Orthologs mouse all