HOXA11, Official Symbol HOXA11provided by HGNC Official Full Name homeobox A11provided by HGNC Primary source HGNC:HGNC:5101 See related Ensembl:ENSG00000005073 MIM:142958; AllianceGenome:HGNC:5101 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HOX1; HOX1I; RUSAT1 Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008] Expression Biased expression in endometrium (RPKM 34.9), prostate (RPKM 6.8) and 4 other tissues See more Orthologs mouse all