MMP19, Official Symbol MMP19provided by HGNC Official Full Name matrix metallopeptidase 19provided by HGNC Primary source HGNC:HGNC:7165 See related Ensembl:ENSG00000123342 MIM:601807; AllianceGenome:HGNC:7165 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CODA; MMP18; RASI-1 Summary This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013] Expression Broad expression in gall bladder (RPKM 58.3), appendix (RPKM 21.2) and 19 other tissues See more Orthologs mouse all