GBP3, Official Symbol GBP3provided by HGNC Official Full Name guanylate binding protein 3provided by HGNC Primary source HGNC:HGNC:4184 See related Ensembl:ENSG00000117226 MIM:600413; AllianceGenome:HGNC:4184 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2017] Expression Broad expression in duodenum (RPKM 41.6), small intestine (RPKM 35.5) and 23 other tissues See more Orthologs all