PCDH12, Official Symbol PCDH12provided by HGNC Official Full Name protocadherin 12provided by HGNC Primary source HGNC:HGNC:8657 See related Ensembl:ENSG00000113555 MIM:605622; AllianceGenome:HGNC:8657 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DMJDS1; VECAD2; VE-cadherin-2 Summary This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth. [provided by RefSeq, Jul 2008] Expression Broad expression in placenta (RPKM 15.3), lung (RPKM 10.9) and 20 other tissues See more Orthologs mouse all