MLYCD, Official Symbol MLYCDprovided by HGNC Official Full Name malonyl-CoA decarboxylaseprovided by HGNC Primary source HGNC:HGNC:7150 See related Ensembl:ENSG00000103150 MIM:606761; AllianceGenome:HGNC:7150 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCD Summary The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 24.2), liver (RPKM 11.1) and 24 other tissues See more Orthologs mouse all