TBPL1, Official Symbol TBPL1provided by HGNC Official Full Name TATA-box binding protein like 1provided by HGNC Primary source HGNC:HGNC:11589 See related Ensembl:ENSG00000028839 MIM:605521; AllianceGenome:HGNC:11589 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TLF; TLP; STUD; TRF2; MGC:8389; MGC:9620 Summary This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Nov 2011] Expression Broad expression in testis (RPKM 58.3), bone marrow (RPKM 8.1) and 20 other tissues See more Orthologs mouse all