MORC2, Official Symbol MORC2provided by HGNC Official Full Name MORC family CW-type zinc finger 2provided by HGNC Primary source HGNC:HGNC:23573 See related Ensembl:ENSG00000133422 MIM:616661; AllianceGenome:HGNC:23573 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ZCW3; CMT2Z; DIGFAN; ZCWCC1 Summary This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] Expression Broad expression in testis (RPKM 20.8), ovary (RPKM 5.3) and 24 other tissues See more Orthologs mouse all