GZMM, Official Symbol GZMMprovided by HGNC Official Full Name granzyme Mprovided by HGNC Primary source HGNC:HGNC:4712 See related Ensembl:ENSG00000197540 MIM:600311; AllianceGenome:HGNC:4712 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MET1; LMET1 Summary Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] Expression Biased expression in spleen (RPKM 8.2), lymph node (RPKM 6.5) and 13 other tissues See more Orthologs mouse all