NOP53, Official Symbol NOP53provided by HGNC Official Full Name NOP53 ribosome biogenesis factorprovided by HGNC Primary source HGNC:HGNC:4333 See related Ensembl:ENSG00000105373 MIM:605691; AllianceGenome:HGNC:4333 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PICT1; PICT-1; GLTSCR2 Summary Enables 5S rRNA binding activity; identical protein binding activity; and p53 binding activity. Involved in several processes, including negative regulation of transcription, DNA-templated; regulation of cellular protein metabolic process; and regulation of intracellular signal transduction. Located in cytosol; fibrillar center; and nucleoplasm. Colocalizes with rDNA heterochromatin. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in ovary (RPKM 175.8), spleen (RPKM 136.0) and 25 other tissues See more Orthologs mouse all