CFAP410, Official Symbol CFAP410provided by HGNC Official Full Name cilia and flagella associated protein 410provided by HGNC Primary source HGNC:HGNC:1260 See related Ensembl:ENSG00000160226 MIM:603191; AllianceGenome:HGNC:1260 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RDMS; SMDAX; LRRC76; YF5/A2; C21orf2 Summary Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients. [provided by RefSeq, Sep 2012] Expression Ubiquitous expression in kidney (RPKM 7.1), spleen (RPKM 5.4) and 25 other tissues See more Orthologs mouse all