CALCR, Official Symbol CALCRprovided by HGNC Official Full Name calcitonin receptorprovided by HGNC Primary source HGNC:HGNC:1440 See related Ensembl:ENSG00000004948 MIM:114131; AllianceGenome:HGNC:1440 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRT; CTR; CT-R; CTR1 Summary This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] Expression Low expression observed in reference dataset See more Orthologs mouse all