HBEGF, Official Symbol HBEGFprovided by HGNC Official Full Name heparin binding EGF like growth factorprovided by HGNC Primary source HGNC:HGNC:3059 See related Ensembl:ENSG00000113070 MIM:126150; AllianceGenome:HGNC:3059 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DTR; DTS; DTSF; HEGFL Summary Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in gall bladder (RPKM 39.1), esophagus (RPKM 22.6) and 20 other tissues See more Orthologs mouse all