CKB, Official Symbol CKBprovided by HGNC Official Full Name creatine kinase Bprovided by HGNC Primary source HGNC:HGNC:1991 See related Ensembl:ENSG00000166165 MIM:123280; AllianceGenome:HGNC:1991 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCK; B-CK; CKBB; CPK-B; HEL-211; HEL-S-29 Summary The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008] Expression Broad expression in colon (RPKM 268.3), prostate (RPKM 227.9) and 18 other tissues See more Orthologs mouse all