SEC61G, Official Symbol SEC61Gprovided by HGNC Official Full Name SEC61 translocon subunit gammaprovided by HGNC Primary source HGNC:HGNC:18277 See related Ensembl:ENSG00000132432 MIM:609215; AllianceGenome:HGNC:18277 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SSS1 Summary The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in colon (RPKM 71.5), prostate (RPKM 56.4) and 25 other tissues See more Orthologs mouse all