HPGD, Official Symbol HPGDprovided by HGNC Official Full Name 15-hydroxyprostaglandin dehydrogenaseprovided by HGNC Primary source HGNC:HGNC:5154 See related Ensembl:ENSG00000164120 MIM:601688; AllianceGenome:HGNC:5154 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGDH; PGDH1; PHOAR1; 15-PGDH; SDR36C1 Summary This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] Expression Biased expression in urinary bladder (RPKM 176.8), stomach (RPKM 67.9) and 11 other tissues See more Orthologs mouse all