SCARF2, Official Symbol SCARF2provided by HGNC Official Full Name scavenger receptor class F member 2provided by HGNC Primary source HGNC:HGNC:19869 See related Ensembl:ENSG00000244486 MIM:613619; AllianceGenome:HGNC:19869 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NSR1; SREC2; VDEGS; SREC-II; SRECRP-1 Summary The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Expression Broad expression in fat (RPKM 3.8), prostate (RPKM 3.4) and 24 other tissues See more Orthologs mouse all