GRIK4, Official Symbol GRIK4provided by HGNC Official Full Name glutamate ionotropic receptor kainate type subunit 4provided by HGNC Primary source HGNC:HGNC:4582 See related Ensembl:ENSG00000149403 MIM:600282; AllianceGenome:HGNC:4582 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KA1; EAA1; GRIK; GluK4; GluK4-2 Summary This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Expression Biased expression in brain (RPKM 2.8), ovary (RPKM 0.9) and 4 other tissues See more Orthologs mouse all