VPS39, Official Symbol VPS39provided by HGNC Official Full Name VPS39 subunit of HOPS complexprovided by HGNC Primary source HGNC:HGNC:20593 See related Ensembl:ENSG00000166887 MIM:612188; AllianceGenome:HGNC:20593 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TLP; VAM6; hVam6p Summary This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in brain (RPKM 16.3), thyroid (RPKM 14.7) and 25 other tissues See more Orthologs mouse all