PROCR, Official Symbol PROCRprovided by HGNC Official Full Name protein C receptorprovided by HGNC Primary source HGNC:HGNC:9452 See related Ensembl:ENSG00000101000 MIM:600646; AllianceGenome:HGNC:9452 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CCCA; EPCR; CCD41 Summary The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013] Expression Ubiquitous expression in placenta (RPKM 14.7), fat (RPKM 10.7) and 24 other tissues See more Orthologs mouse all