ADAM28, Official Symbol ADAM28provided by HGNC Official Full Name ADAM metallopeptidase domain 28provided by HGNC Primary source HGNC:HGNC:206 See related Ensembl:ENSG00000042980 MIM:606188; AllianceGenome:HGNC:206 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MDCL; MDC-L; eMDCII; ADAM 28; eMDC II Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Expression Biased expression in stomach (RPKM 21.4), gall bladder (RPKM 11.1) and 12 other tissues See more Orthologs mouse all