ANXA9, Official Symbol ANXA9provided by HGNC Official Full Name annexin A9provided by HGNC Primary source HGNC:HGNC:547 See related Ensembl:ENSG00000143412 MIM:603319; AllianceGenome:HGNC:547 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ANX31 Summary The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 12.1), thyroid (RPKM 11.7) and 23 other tissues See more Orthologs mouse all