PMEPA1, Official Symbol PMEPA1provided by HGNC Official Full Name prostate transmembrane protein, androgen induced 1provided by HGNC Primary source HGNC:HGNC:14107 See related Ensembl:ENSG00000124225 MIM:606564; AllianceGenome:HGNC:14107 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as STAG1; TMEPAI Summary This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Expression Broad expression in prostate (RPKM 54.2), fat (RPKM 28.9) and 20 other tissues See more Orthologs mouse all