GSN, Official Symbol GSNprovided by HGNC Official Full Name gelsolinprovided by HGNC Primary source HGNC:HGNC:4620 See related Ensembl:ENSG00000148180 MIM:137350; AllianceGenome:HGNC:4620 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADF; AGEL Summary The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in fat (RPKM 444.2), heart (RPKM 172.6) and 23 other tissues See more Orthologs mouse all