IQGAP3, Official Symbol IQGAP3provided by HGNC Official Full Name IQ motif containing GTPase activating protein 3provided by HGNC Primary source HGNC:HGNC:20669 See related Ensembl:ENSG00000183856 AllianceGenome:HGNC:20669 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables calmodulin binding activity and myosin VI light chain binding activity. Predicted to be involved in regulation of actin cytoskeleton organization. Predicted to act upstream of or within several processes, including intracellular signal transduction; positive regulation of macromolecule metabolic process; and positive regulation of mammary gland epithelial cell proliferation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 5.6), duodenum (RPKM 3.0) and 16 other tissues See more Orthologs mouse all