TRPM1, Official Symbol TRPM1provided by HGNC Official Full Name transient receptor potential cation channel subfamily M member 1provided by HGNC Primary source HGNC:HGNC:7146 See related Ensembl:ENSG00000134160 MIM:603576; AllianceGenome:HGNC:7146 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MLSN1; CSNB1C; LTRPC1 Summary This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011] Expression Biased expression in skin (RPKM 2.8) and testis (RPKM 1.1) See more Orthologs mouse all