PCSK1N, Official Symbol PCSK1Nprovided by HGNC Official Full Name proprotein convertase subtilisin/kexin type 1 inhibitorprovided by HGNC Primary source HGNC:HGNC:17301 See related Ensembl:ENSG00000102109 MIM:300399; AllianceGenome:HGNC:17301 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PEN; SAAS; SCG8; BigLEN; SgVIII; PROSAAS Summary The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity. [provided by RefSeq, Aug 2013] Expression Biased expression in kidney (RPKM 101.8), brain (RPKM 31.9) and 2 other tissues See more Orthologs mouse all