ZBP1, Official Symbol ZBP1provided by HGNC Official Full Name Z-DNA binding protein 1provided by HGNC Primary source HGNC:HGNC:16176 See related Ensembl:ENSG00000124256 MIM:606750; AllianceGenome:HGNC:16176 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DAI; DLM1; DLM-1; C20orf183 Summary This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Annotation information Note: ZBP1 (Gene ID: 81030) and IGF2BP1 (Gene ID:10642) share the ZBP1 symbol/alias in common. ZBP1 is a widely used alternative name for insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1), which can be confused with the official symbol for ZBP1, Z-DNA binding protein 1 (ZBP1). [09 Aug 2021] Expression Biased expression in spleen (RPKM 3.6), appendix (RPKM 3.2) and 13 other tissues See more Orthologs mouse all