ANKLE2, Official Symbol ANKLE2provided by HGNC Official Full Name ankyrin repeat and LEM domain containing 2provided by HGNC Primary source HGNC:HGNC:29101 See related Ensembl:ENSG00000176915 MIM:616062; AllianceGenome:HGNC:29101 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Lem4; LEMD7; MCPH16; KIAA0692 Summary This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation. [provided by RefSeq, Mar 2014] Expression Ubiquitous expression in testis (RPKM 31.1), lymph node (RPKM 13.1) and 25 other tissues See more Orthologs mouse all