TTBK2, Official Symbol TTBK2provided by HGNC Official Full Name tau tubulin kinase 2provided by HGNC Primary source HGNC:HGNC:19141 See related Ensembl:ENSG00000128881 MIM:611695; AllianceGenome:HGNC:19141 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTBK; SCA11 Summary This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. [provided by RefSeq, Aug 2009] Expression Broad expression in testis (RPKM 9.5), brain (RPKM 5.6) and 24 other tissues See more Orthologs mouse all