AURKC, Official Symbol AURKCprovided by HGNC Official Full Name aurora kinase Cprovided by HGNC Primary source HGNC:HGNC:11391 See related Ensembl:ENSG00000105146 MIM:603495; AllianceGenome:HGNC:11391 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AIE2; AIK3; ARK3; AurC; SPGF5; STK13; HEL-S-90; aurora-C Summary This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] Expression Biased expression in testis (RPKM 14.8), brain (RPKM 1.0) and 1 other tissue See more Orthologs mouse all