AACS, Official Symbol AACSprovided by HGNC Official Full Name acetoacetyl-CoA synthetaseprovided by HGNC Primary source HGNC:HGNC:21298 See related Ensembl:ENSG00000081760 MIM:614364; AllianceGenome:HGNC:21298 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACSF1; SUR-5 Summary Predicted to enable acetoacetate-CoA ligase activity. Predicted to be involved in positive regulation of insulin secretion. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in fat (RPKM 23.3), skin (RPKM 16.5) and 24 other tissues See more Orthologs mouse all