LCN2, Official Symbol LCN2provided by HGNC Official Full Name lipocalin 2provided by HGNC Primary source HGNC:HGNC:6526 See related Ensembl:ENSG00000148346 MIM:600181; AllianceGenome:HGNC:6526 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as p25; 24p3; MSFI; NGAL Summary This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015] Expression Biased expression in gall bladder (RPKM 1027.2), bone marrow (RPKM 834.0) and 5 other tissues See more Orthologs mouse all