DNM2, Official Symbol DNM2provided by HGNC Official Full Name dynamin 2provided by HGNC Primary source HGNC:HGNC:2974 See related Ensembl:ENSG00000079805 MIM:602378; AllianceGenome:HGNC:2974 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB Summary Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010] Expression Ubiquitous expression in colon (RPKM 49.5), stomach (RPKM 41.1) and 25 other tissues See more Orthologs mouse all