NDUFB2, Official Symbol NDUFB2provided by HGNC Official Full Name NADH:ubiquinone oxidoreductase subunit B2provided by HGNC Primary source HGNC:HGNC:7697 See related Ensembl:ENSG00000090266 MIM:603838; AllianceGenome:HGNC:7697 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AGGG; CI-AGGG Summary The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in heart (RPKM 93.9), kidney (RPKM 78.0) and 25 other tissues See more Orthologs mouse all