ARHGEF10L, Official Symbol ARHGEF10Lprovided by HGNC Official Full Name Rho guanine nucleotide exchange factor 10 likeprovided by HGNC Primary source HGNC:HGNC:25540 See related Ensembl:ENSG00000074964 MIM:612494; AllianceGenome:HGNC:25540 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GrinchGEF Summary This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2016] Expression Ubiquitous expression in kidney (RPKM 7.7), colon (RPKM 6.9) and 24 other tissues See more Orthologs mouse all