CASTOR1, Official Symbol CASTOR1provided by HGNC Official Full Name cytosolic arginine sensor for mTORC1 subunit 1provided by HGNC Primary source HGNC:HGNC:34423 See related Ensembl:ENSG00000239282 MIM:617034; AllianceGenome:HGNC:34423 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GATSL3 Summary Enables arginine binding activity and identical protein binding activity. Involved in cellular response to L-arginine and negative regulation of TORC1 signaling. Located in cytosol. Colocalizes with GATOR2 complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in esophagus (RPKM 13.7), placenta (RPKM 8.5) and 22 other tissues See more Orthologs mouse all