ITSN2, Official Symbol ITSN2provided by HGNC Official Full Name intersectin 2provided by HGNC Primary source HGNC:HGNC:6184 See related Ensembl:ENSG00000198399 MIM:604464; AllianceGenome:HGNC:6184 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SWA; SWAP; SH3D1B; SH3P18; PRO2015 Summary This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. [provided by RefSeq, Jan 2017] Expression Ubiquitous expression in thyroid (RPKM 16.9), lymph node (RPKM 13.9) and 25 other tissues See more Orthologs mouse all