PPA2, Official Symbol PPA2provided by HGNC Official Full Name inorganic pyrophosphatase 2provided by HGNC Primary source HGNC:HGNC:28883 See related Ensembl:ENSG00000138777 MIM:609988; AllianceGenome:HGNC:28883 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCFI; SCFAI; HSPC124; SID6-306 Summary The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in kidney (RPKM 25.8), colon (RPKM 25.1) and 25 other tissues See more Orthologs mouse all