PCED1A, Official Symbol PCED1Aprovided by HGNC Official Full Name PC-esterase domain containing 1Aprovided by HGNC Primary source HGNC:HGNC:16212 See related Ensembl:ENSG00000132635 AllianceGenome:HGNC:16212 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FAM113A; C20orf81; bA12M19.1 Summary The protein encoded by this gene is a member of the GDSL/SGNH superfamily. Members of this family are hydrolytic enzymes with esterase and lipase activity and broad substrate specificity. This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine, aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif). A pseudogene of this gene has been identified on the long arm of chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012] Expression Ubiquitous expression in spleen (RPKM 18.9), thyroid (RPKM 14.9) and 25 other tissues See more Orthologs mouse all