BCL2, Official Symbol BCL2provided by HGNC Official Full Name BCL2 apoptosis regulatorprovided by HGNC Primary source HGNC:HGNC:990 See related Ensembl:ENSG00000171791 MIM:151430; AllianceGenome:HGNC:990 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Bcl-2; PPP1R50 Summary This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] Expression Broad expression in thyroid (RPKM 21.9), spleen (RPKM 9.1) and 20 other tissues See more Orthologs mouse all