LCP1, Official Symbol LCP1provided by HGNC Official Full Name lymphocyte cytosolic protein 1provided by HGNC Primary source HGNC:HGNC:6528 See related Ensembl:ENSG00000136167 MIM:153430; AllianceGenome:HGNC:6528 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN Summary Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008] Expression Broad expression in lymph node (RPKM 278.7), bone marrow (RPKM 256.8) and 18 other tissues See more Orthologs mouse all