ENAM, Official Symbol ENAMprovided by HGNC Official Full Name enamelinprovided by HGNC Primary source HGNC:HGNC:3344 See related Ensembl:ENSG00000132464 MIM:606585; AllianceGenome:HGNC:3344 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ADAI; AI1C; AIH2 Summary Dental enamel forms the outer cap of teeth and is the hardest substance found in vertebrates. This gene encodes the largest protein in the enamel matrix of developing teeth. The protein is involved in the mineralization and structural organization of enamel. Defects in this gene result in amelogenesis imperfect type 1C.[provided by RefSeq, Oct 2009] Expression Biased expression in kidney (RPKM 2.0), heart (RPKM 1.3) and 5 other tissues See more Orthologs mouse all