FEM1C, Official Symbol FEM1Cprovided by HGNC Official Full Name fem-1 homolog Cprovided by HGNC Primary source HGNC:HGNC:16933 See related Ensembl:ENSG00000145780 MIM:608767; AllianceGenome:HGNC:16933 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FEM1A; EUROIMAGE686608; EUROIMAGE783647 Summary Enables ubiquitin ligase-substrate adaptor activity. Involved in ubiquitin-dependent protein catabolic process via the C-end degron rule pathway. Located in cytosol and nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 24.9), testis (RPKM 9.4) and 25 other tissues See more Orthologs mouse all