ASTL, Official Symbol ASTLprovided by HGNC Official Full Name astacin like metalloendopeptidaseprovided by HGNC Primary source HGNC:HGNC:31704 See related Ensembl:ENSG00000188886 MIM:608860; AllianceGenome:HGNC:31704 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SAS1B; OOMD11; OZEMA11 Summary Predicted to enable aspartic-type peptidase activity; glutamic-type peptidase activity; and metalloendopeptidase activity. Predicted to be involved in several processes, including negative regulation of binding activity of sperm to zona pellucida; positive regulation of protein processing; and prevention of polyspermy. Predicted to be located in cortical granule and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in bone marrow (RPKM 1.1), skin (RPKM 0.2) and 10 other tissues See more Orthologs mouse all