NUFIP1, Official Symbol NUFIP1provided by HGNC Official Full Name nuclear FMR1 interacting protein 1provided by HGNC Primary source HGNC:HGNC:8057 See related Ensembl:ENSG00000083635 MIM:604354; AllianceGenome:HGNC:8057 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Rsa1; NUFIP; bA540M5.1 Summary This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012] Expression Ubiquitous expression in testis (RPKM 3.6), brain (RPKM 2.9) and 25 other tissues See more Orthologs mouse all