CEP19, Official Symbol CEP19provided by HGNC Official Full Name centrosomal protein 19provided by HGNC Primary source HGNC:HGNC:28209 See related Ensembl:ENSG00000174007 MIM:615586; AllianceGenome:HGNC:28209 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MOSPGF; C3orf34 Summary The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole. This gene resides in a region of human chromosome 3 that is linked to morbid obesity. A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance. Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF). This gene has a pseudogene on human chromosome 2. [provided by RefSeq, Apr 2014] Expression Broad expression in testis (RPKM 6.7), brain (RPKM 1.9) and 21 other tissues See more Orthologs mouse all