MYBPC3, Official Symbol MYBPC3provided by HGNC Official Full Name myosin binding protein C3provided by HGNC Primary source HGNC:HGNC:7551 See related Ensembl:ENSG00000134571 MIM:600958; AllianceGenome:HGNC:7551 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FHC; CMH4; CMD1MM; LVNC10; MYBP-C; cMyBP-C Summary MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3 is expressed exclusively in heart muscle and is a key regulator of cardiac contraction. Mutations in this gene are a frequent cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, May 2022] Expression Restricted expression toward heart (RPKM 426.0) See more Orthologs mouse all