NEK1, Official Symbol NEK1provided by HGNC Official Full Name NIMA related kinase 1provided by HGNC Primary source HGNC:HGNC:7744 See related Ensembl:ENSG00000137601 MIM:604588; AllianceGenome:HGNC:7744 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ALS24; SRPS2; SRTD6; SRPS2A; NY-REN-55 Summary The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in testis (RPKM 6.8), brain (RPKM 4.8) and 25 other tissues See more Orthologs mouse all