CPA4, Official Symbol CPA4provided by HGNC Official Full Name carboxypeptidase A4provided by HGNC Primary source HGNC:HGNC:15740 See related Ensembl:ENSG00000128510 MIM:607635; AllianceGenome:HGNC:15740 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CPA3 Summary This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008] Expression Biased expression in skin (RPKM 24.3) and esophagus (RPKM 4.3) See more Orthologs all