PIGT, Official Symbol PIGTprovided by HGNC Official Full Name phosphatidylinositol glycan anchor biosynthesis class Tprovided by HGNC Primary source HGNC:HGNC:14938 See related Ensembl:ENSG00000124155 MIM:610272; AllianceGenome:HGNC:14938 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NDAP; PNH2; PIG-T; CGI-06; MCAHS3 Summary This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] Expression Ubiquitous expression in heart (RPKM 45.9), colon (RPKM 41.3) and 25 other tissues See more Orthologs mouse all