ANO1, Official Symbol ANO1provided by HGNC Official Full Name anoctamin 1provided by HGNC Primary source HGNC:HGNC:21625 See related Ensembl:ENSG00000131620 MIM:610108; AllianceGenome:HGNC:21625 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DOG1; INDMS; TAOS2; ORAOV2; TMEM16A Summary Enables calcium activated cation channel activity; intracellular calcium activated chloride channel activity; and iodide transmembrane transporter activity. Involved in cation transport; inorganic anion transport; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in apical plasma membrane and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in skin (RPKM 23.9), salivary gland (RPKM 22.1) and 16 other tissues See more Orthologs mouse all