TNFRSF19, Official Symbol TNFRSF19provided by HGNC Official Full Name TNF receptor superfamily member 19provided by HGNC Primary source HGNC:HGNC:11915 See related Ensembl:ENSG00000127863 MIM:606122; AllianceGenome:HGNC:11915 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TAJ; TROY; TRADE; TAJ-alpha Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] Expression Biased expression in skin (RPKM 37.6), prostate (RPKM 12.9) and 8 other tissues See more Orthologs mouse all