PPCDC, Official Symbol PPCDCprovided by HGNC Official Full Name phosphopantothenoylcysteine decarboxylaseprovided by HGNC Primary source HGNC:HGNC:28107 See related Ensembl:ENSG00000138621 MIM:609854; AllianceGenome:HGNC:28107 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as coaC; MDS018; PPC-DC Summary Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in bone marrow (RPKM 1.6), appendix (RPKM 1.5) and 25 other tissues See more Orthologs mouse all