GRIA1, Official Symbol GRIA1provided by HGNC Official Full Name glutamate ionotropic receptor AMPA type subunit 1provided by HGNC Primary source HGNC:HGNC:4571 See related Ensembl:ENSG00000155511 MIM:138248; AllianceGenome:HGNC:4571 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLUH1; GLUR1; GLURA; GluA1; HBGR1; MRD67; MRT76 Summary Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 23.3) and lung (RPKM 3.7) See more Orthologs mouse all