PDE2A, Official Symbol PDE2Aprovided by HGNC Official Full Name phosphodiesterase 2Aprovided by HGNC Primary source HGNC:HGNC:8777 See related Ensembl:ENSG00000186642 MIM:602658; AllianceGenome:HGNC:8777 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PDE2A1; PED2A4; cGSPDE; CGS-PDE; IDDPADS Summary Enables several functions, including 3',5'-cyclic-nucleotide phosphodiesterase activity; anion binding activity; and metal ion binding activity. Involved in several processes, including cellular response to organic cyclic compound; cyclic-nucleotide-mediated signaling; and regulation of vascular permeability. Located in several cellular components, including cytosol; mitochondrial membrane; and perinuclear region of cytoplasm. Colocalizes with plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in spleen (RPKM 45.0), brain (RPKM 27.8) and 14 other tissues See more Orthologs mouse all