SLC4A8, Official Symbol SLC4A8provided by HGNC Official Full Name solute carrier family 4 member 8provided by HGNC Primary source HGNC:HGNC:11034 See related Ensembl:ENSG00000050438 MIM:605024; AllianceGenome:HGNC:11034 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NBC3; NDCBE Summary The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] Expression Biased expression in testis (RPKM 5.0), brain (RPKM 4.6) and 9 other tissues See more Orthologs mouse all