DNAJC24, Official Symbol DNAJC24provided by HGNC Official Full Name DnaJ heat shock protein family (Hsp40) member C24provided by HGNC Primary source HGNC:HGNC:26979 See related Ensembl:ENSG00000170946 MIM:611072; AllianceGenome:HGNC:26979 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DPH4; JJJ3; ZCSL3 Summary Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008] Expression Ubiquitous expression in fat (RPKM 5.9), skin (RPKM 5.2) and 25 other tissues See more Orthologs mouse all