GPR18, Official Symbol GPR18provided by HGNC Official Full Name G protein-coupled receptor 18provided by HGNC Primary source HGNC:HGNC:4472 See related Ensembl:ENSG00000125245 MIM:602042; AllianceGenome:HGNC:4472 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DRV2 Summary Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to act upstream of or within T cell differentiation; negative regulation of leukocyte chemotaxis; and negative regulation of tumor necrosis factor production. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in lymph node (RPKM 11.0), testis (RPKM 4.7) and 4 other tissues See more Orthologs mouse all