DCXR, Official Symbol DCXRprovided by HGNC Official Full Name dicarbonyl and L-xylulose reductaseprovided by HGNC Primary source HGNC:HGNC:18985 See related Ensembl:ENSG00000169738 MIM:608347; AllianceGenome:HGNC:18985 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as XR; DCR; HCR2; P34H; HCRII; KIDCR; PNTSU; SDR20C1 Summary The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010] Expression Biased expression in liver (RPKM 345.1), kidney (RPKM 158.4) and 7 other tissues See more Orthologs mouse all