SH3KBP1, Official Symbol SH3KBP1provided by HGNC Official Full Name SH3 domain containing kinase binding protein 1provided by HGNC Primary source HGNC:HGNC:13867 See related Ensembl:ENSG00000147010 MIM:300374; AllianceGenome:HGNC:13867 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HSB1; AGMX2; CIN85; GIG10; HSB-1; IMD61; MIG18; CD2BP3 Summary This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017] Expression Ubiquitous expression in lymph node (RPKM 19.2), fat (RPKM 15.0) and 24 other tissues See more Orthologs mouse all