IRF7, Official Symbol IRF7provided by HGNC Official Full Name interferon regulatory factor 7provided by HGNC Primary source HGNC:HGNC:6122 See related Ensembl:ENSG00000185507 MIM:605047; AllianceGenome:HGNC:6122 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IMD39; IRF-7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H Summary This gene encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. It has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. The encoded protein plays an important role in the innate immune response against DNA and RNA viruses. [provided by RefSeq, Jul 2021] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in immune response or antiviral activity. Expression Broad expression in spleen (RPKM 16.7), lymph node (RPKM 8.9) and 24 other tissues See more Orthologs mouse all