NMB, Official Symbol NMBprovided by HGNC Official Full Name neuromedin Bprovided by HGNC Primary source HGNC:HGNC:7842 See related Ensembl:ENSG00000197696 MIM:162340; AllianceGenome:HGNC:7842 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] Expression Biased expression in fat (RPKM 21.3), brain (RPKM 11.2) and 5 other tissues See more Orthologs mouse all