MNAT1, Official Symbol MNAT1provided by HGNC Official Full Name MNAT1 component of CDK activating kinaseprovided by HGNC Primary source HGNC:HGNC:7181 See related Ensembl:ENSG00000020426 MIM:602659; AllianceGenome:HGNC:7181 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MAT1; TFB3; CAP35; RNF66 Summary The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Expression Ubiquitous expression in fat (RPKM 3.3), prostate (RPKM 3.0) and 25 other tissues See more Orthologs mouse all