SSH2, Official Symbol SSH2provided by HGNC Official Full Name slingshot protein phosphatase 2provided by HGNC Primary source HGNC:HGNC:30580 See related Ensembl:ENSG00000141298 MIM:606779; AllianceGenome:HGNC:30580 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SSH-2; SSH-2L Summary This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Expression Broad expression in lymph node (RPKM 6.2), appendix (RPKM 6.0) and 24 other tissues See more Orthologs mouse all