FOXO3, Official Symbol FOXO3provided by HGNC Official Full Name forkhead box O3provided by HGNC Primary source HGNC:HGNC:3821 See related Ensembl:ENSG00000118689 MIM:602681; AllianceGenome:HGNC:3821 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2 Summary This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 14.1), bone marrow (RPKM 13.9) and 25 other tissues See more Orthologs mouse all