PRDM6, Official Symbol PRDM6provided by HGNC Official Full Name PR/SET domain 6provided by HGNC Primary source HGNC:HGNC:9350 See related Ensembl:ENSG00000061455 MIM:616982; AllianceGenome:HGNC:9350 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PDA3; KMT8C; PRISM Summary The protein encoded by this gene is a transcriptional repressor and a member of the PRDM family. Family members contain a PR domain and multiple zinc-finger domains. The encoded protein is involved in regulation of vascular smooth muscle cells (VSMC) contractile proteins. Mutations in this gene result in patent ductus arteriosus 3 (PDA3). [provided by RefSeq, Apr 2017] Expression Broad expression in gall bladder (RPKM 2.3), placenta (RPKM 2.0) and 16 other tissues See more Orthologs mouse all