PLD4, Official Symbol PLD4provided by HGNC Official Full Name phospholipase D family member 4provided by HGNC Primary source HGNC:HGNC:23792 See related Ensembl:ENSG00000166428 MIM:618488; AllianceGenome:HGNC:23792 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as C14orf175 Summary Predicted to enable single-stranded DNA 5'-3' exodeoxyribonuclease activity. Predicted to be involved in hematopoietic progenitor cell differentiation; phagocytosis; and regulation of cytokine production involved in inflammatory response. Predicted to be located in early endosome and endoplasmic reticulum membrane. Predicted to be active in several cellular components, including endoplasmic reticulum; phagocytic vesicle; and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in skin (RPKM 31.7), spleen (RPKM 4.6) and 9 other tissues See more Orthologs mouse all