ADAM12, Official Symbol ADAM12provided by HGNC Official Full Name ADAM metallopeptidase domain 12provided by HGNC Primary source HGNC:HGNC:190 See related Ensembl:ENSG00000148848 MIM:602714; AllianceGenome:HGNC:190 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MCMP; MLTN; CAR10; MLTNA; MCMPMltna; ADAM12-OT1 Summary This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014] Expression Biased expression in placenta (RPKM 63.0), gall bladder (RPKM 5.5) and 2 other tissues See more Orthologs mouse all