TNFSF13B, Official Symbol TNFSF13Bprovided by HGNC Official Full Name TNF superfamily member 13bprovided by HGNC Primary source HGNC:HGNC:11929 See related Ensembl:ENSG00000102524 MIM:603969; AllianceGenome:HGNC:11929 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20 Summary The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011] Expression Broad expression in appendix (RPKM 11.4), lymph node (RPKM 7.1) and 21 other tissues See more Orthologs mouse all