HUS1B, Official Symbol HUS1Bprovided by HGNC Official Full Name HUS1 checkpoint clamp component Bprovided by HGNC Primary source HGNC:HGNC:16485 See related Ensembl:ENSG00000188996 MIM:609713; AllianceGenome:HGNC:16485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008] Orthologs mouse all