PTPN23, Official Symbol PTPN23provided by HGNC Official Full Name protein tyrosine phosphatase non-receptor type 23provided by HGNC Primary source HGNC:HGNC:14406 See related Ensembl:ENSG00000076201 MIM:606584; AllianceGenome:HGNC:14406 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HDPTP; HD-PTP; NEDBASS; PTP-TD14 Summary This gene encodes a member of the non-receptor type protein-tyrosine phosphatase family. The encoded protein may be involved in the regulation of small nuclear ribonucleo protein assembly and pre-mRNA splicing by modifying the survival motor neuron (SMN) complex. The encoded protein additionally plays a role in ciliogenesis and is part of endosomal sorting complex required for transport (ESCRT) pathways. This gene may serve a tumor suppressor function. [provided by RefSeq, Jul 2016] Expression Ubiquitous expression in spleen (RPKM 10.2), brain (RPKM 9.8) and 25 other tissues See more Orthologs mouse all