RCC2, Official Symbol RCC2provided by HGNC Official Full Name regulator of chromosome condensation 2provided by HGNC Primary source HGNC:HGNC:30297 See related Ensembl:ENSG00000179051 MIM:609587; AllianceGenome:HGNC:30297 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TD-60 Summary The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer. [provided by RefSeq, Oct 2016] Expression Ubiquitous expression in lymph node (RPKM 29.5), skin (RPKM 28.3) and 25 other tissues See more Orthologs mouse all