RYR3, Official Symbol RYR3provided by HGNC Official Full Name ryanodine receptor 3provided by HGNC Primary source HGNC:HGNC:10485 See related Ensembl:ENSG00000198838 MIM:180903; AllianceGenome:HGNC:10485 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RYR-3; CMYP20 Summary The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Expression Broad expression in brain (RPKM 1.5), endometrium (RPKM 1.4) and 19 other tissues See more Orthologs mouse all