CKM, Official Symbol CKMprovided by HGNC Official Full Name creatine kinase, M-typeprovided by HGNC Primary source HGNC:HGNC:1994 See related Ensembl:ENSG00000104879 MIM:123310; AllianceGenome:HGNC:1994 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CKMM; M-CK; CPK-M Summary The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008] Expression Biased expression in heart (RPKM 751.9), esophagus (RPKM 219.5) and 1 other tissue See more Orthologs mouse all