PIP5K1A, Official Symbol PIP5K1Aprovided by HGNC Official Full Name phosphatidylinositol-4-phosphate 5-kinase type 1 alphaprovided by HGNC Primary source HGNC:HGNC:8994 See related Ensembl:ENSG00000143398 MIM:603275; AllianceGenome:HGNC:8994 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity and kinase binding activity. Involved in several processes, including activation of GTPase activity; focal adhesion assembly; and ruffle assembly. Located in several cellular components, including lamellipodium; nuclear speck; and ruffle membrane. Colocalizes with mRNA cleavage and polyadenylation specificity factor complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 22.2), placenta (RPKM 13.0) and 25 other tissues See more Orthologs mouse all