MAL2, Official Symbol MAL2provided by HGNC Official Full Name mal, T cell differentiation protein 2provided by HGNC Primary source HGNC:HGNC:13634 See related Ensembl:ENSG00000147676 MIM:609684; AllianceGenome:HGNC:13634 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface. [provided by RefSeq, Jul 2008] Expression Broad expression in esophagus (RPKM 140.3), thyroid (RPKM 100.0) and 16 other tissues See more Orthologs mouse all