CHIC1, Official Symbol CHIC1provided by HGNC Official Full Name cysteine rich hydrophobic domain 1provided by HGNC Primary source HGNC:HGNC:1934 See related Ensembl:ENSG00000204116 MIM:300922; AllianceGenome:HGNC:1934 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BRX Summary This gene encodes a cysteine-rich hydrophobic (CHIC) domain-containing protein, and is one of the few protein-coding genes found near the X-inactivation center. Studies in mouse indicate that the mouse ortholog of this gene is subject to X-inactivation in mouse. Experiments with other CHIC domain-containing family members show that the cysteine residues are palmitoylated post-translationally, resulting in membrane association. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017] Expression Ubiquitous expression in brain (RPKM 2.4), adrenal (RPKM 1.9) and 23 other tissues See more Orthologs mouse all