OTOS, Official Symbol OTOSprovided by HGNC Official Full Name otospiralinprovided by HGNC Primary source HGNC:HGNC:22644 See related Ensembl:ENSG00000178602 MIM:607877; AllianceGenome:HGNC:22644 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OTOSP Summary Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003 [PubMed 12687421]).[supplied by OMIM, Mar 2008] Expression Restricted expression toward thyroid (RPKM 6.1) See more Orthologs mouse all