TMIE, Official Symbol TMIEprovided by HGNC Official Full Name transmembrane inner earprovided by HGNC Primary source HGNC:HGNC:30800 See related Ensembl:ENSG00000181585 MIM:607237; AllianceGenome:HGNC:30800 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNB6 Summary This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment. [provided by RefSeq, Mar 2009] Expression Broad expression in adrenal (RPKM 2.0), brain (RPKM 1.3) and 20 other tissues See more Orthologs mouse all