RTKN2, Official Symbol RTKN2provided by HGNC Official Full Name rhotekin 2provided by HGNC Primary source HGNC:HGNC:19364 See related Ensembl:ENSG00000182010 MIM:618450; AllianceGenome:HGNC:19364 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PLEKHK1; bA531F24.1 Summary Involved in negative regulation of intrinsic apoptotic signaling pathway; positive regulation of NF-kappaB transcription factor activity; and positive regulation of NIK/NF-kappaB signaling. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in lung (RPKM 32.1) and testis (RPKM 2.2) See more Orthologs mouse all