H2AZ2, Official Symbol H2AZ2provided by HGNC Official Full Name H2A.Z variant histone 2provided by HGNC Primary source HGNC:HGNC:20664 See related Ensembl:ENSG00000105968 MIM:620008; AllianceGenome:HGNC:20664 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as H2AV; H2AFV; H2A.Z-2 Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015] Expression Ubiquitous expression in bone marrow (RPKM 39.7), brain (RPKM 29.7) and 25 other tissues See more Orthologs mouse all