SRI, Official Symbol SRIprovided by HGNC Official Full Name sorcinprovided by HGNC Primary source HGNC:HGNC:11292 See related Ensembl:ENSG00000075142 MIM:182520; AllianceGenome:HGNC:11292 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SCN; V19; CP22; CP-22 Summary This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene. [provided by RefSeq, Mar 2012] Expression Broad expression in colon (RPKM 86.4), brain (RPKM 64.5) and 24 other tissues See more Orthologs mouse all