RND3, Official Symbol RND3provided by HGNC Official Full Name Rho family GTPase 3provided by HGNC Primary source HGNC:HGNC:671 See related Ensembl:ENSG00000115963 MIM:602924; AllianceGenome:HGNC:671 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARHE; Rho8; RhoE; memB Summary This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011] Expression Broad expression in esophagus (RPKM 87.1), liver (RPKM 49.1) and 19 other tissues See more Orthologs mouse all