GRB7, Official Symbol GRB7provided by HGNC Official Full Name growth factor receptor bound protein 7provided by HGNC Primary source HGNC:HGNC:4567 See related Ensembl:ENSG00000141738 MIM:601522; AllianceGenome:HGNC:4567 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] Expression Broad expression in kidney (RPKM 6.4), esophagus (RPKM 5.5) and 16 other tissues See more Orthologs mouse all