STUB1, Official Symbol STUB1provided by HGNC Official Full Name STIP1 homology and U-box containing protein 1provided by HGNC Primary source HGNC:HGNC:11427 See related Ensembl:ENSG00000103266 MIM:607207; AllianceGenome:HGNC:11427 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CHIP; SCA48; UBOX1; SCAR16; HSPABP2; NY-CO-7; SDCCAG7 Summary This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2. [provided by RefSeq, Jun 2014] Expression Ubiquitous expression in fat (RPKM 42.9), kidney (RPKM 39.1) and 25 other tissues See more Orthologs mouse all