MED8, Official Symbol MED8provided by HGNC Official Full Name mediator complex subunit 8provided by HGNC Primary source HGNC:HGNC:19971 See related Ensembl:ENSG00000159479 MIM:607956; AllianceGenome:HGNC:19971 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARC32 Summary This gene encodes a protein component of the mediator complex, which aids in transcriptional activation through interaction with RNA polymerase II and gene-specific transcription factors. The encoded protein may also function in ubiquitin ligation and protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013] Expression Ubiquitous expression in thyroid (RPKM 12.7), placenta (RPKM 11.6) and 25 other tissues See more Orthologs mouse all