HS3ST3A1, Official Symbol HS3ST3A1provided by HGNC Official Full Name heparan sulfate-glucosamine 3-sulfotransferase 3A1provided by HGNC Primary source HGNC:HGNC:5196 See related Ensembl:ENSG00000153976 MIM:604057; AllianceGenome:HGNC:5196 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 3OST3A1; 3-OST-3A Summary Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Dec 2014] Expression Broad expression in spleen (RPKM 1.4), ovary (RPKM 1.0) and 20 other tissues See more Orthologs all