FOXO4, Official Symbol FOXO4provided by HGNC Official Full Name forkhead box O4provided by HGNC Primary source HGNC:HGNC:7139 See related Ensembl:ENSG00000184481 MIM:300033; AllianceGenome:HGNC:7139 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AFX; AFX1; MLLT7 Summary This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] Expression Broad expression in placenta (RPKM 74.9), testis (RPKM 15.0) and 21 other tissues See more Orthologs mouse all