WIPI1, Official Symbol WIPI1provided by HGNC Official Full Name WD repeat domain, phosphoinositide interacting 1provided by HGNC Primary source HGNC:HGNC:25471 See related Ensembl:ENSG00000070540 MIM:609224; AllianceGenome:HGNC:25471 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATG18; ATG18A; WIPI49 Summary This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] Expression Ubiquitous expression in placenta (RPKM 11.9), heart (RPKM 11.3) and 25 other tissues See more Orthologs mouse all