AOC1, Official Symbol AOC1provided by HGNC Official Full Name amine oxidase copper containing 1provided by HGNC Primary source HGNC:HGNC:80 See related Ensembl:ENSG00000002726 MIM:104610; AllianceGenome:HGNC:80 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ABP; DAO; KAO; ABP1; DAO1 Summary This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013] Expression Biased expression in placenta (RPKM 229.3), kidney (RPKM 118.3) and 3 other tissues See more Orthologs all