EXO1, Official Symbol EXO1provided by HGNC Official Full Name exonuclease 1provided by HGNC Primary source HGNC:HGNC:3511 See related Ensembl:ENSG00000174371 MIM:606063; AllianceGenome:HGNC:3511 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEX1; hExoI Summary This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008] Expression Biased expression in bone marrow (RPKM 3.9), testis (RPKM 2.9) and 13 other tissues See more Orthologs mouse all