NOX5, Official Symbol NOX5provided by HGNC Official Full Name NADPH oxidase 5provided by HGNC Primary source HGNC:HGNC:14874 See related Ensembl:ENSG00000290203 MIM:606572; AllianceGenome:HGNC:14874 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] Expression Biased expression in spleen (RPKM 7.9), testis (RPKM 4.2) and 3 other tissues See more Orthologs all