SEPTIN1, Official Symbol SEPTIN1provided by HGNC Official Full Name septin 1provided by HGNC Primary source HGNC:HGNC:2879 See related Ensembl:ENSG00000180096 MIM:612897; AllianceGenome:HGNC:2879 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as LARP; SEP1; DIFF6; SEPT1; PNUTL3 Summary This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012] Expression Biased expression in lymph node (RPKM 27.2), spleen (RPKM 18.3) and 9 other tissues See more Orthologs mouse all