HS3ST4, Official Symbol HS3ST4provided by HGNC Official Full Name heparan sulfate-glucosamine 3-sulfotransferase 4provided by HGNC Primary source HGNC:HGNC:5200 See related Ensembl:ENSG00000182601 MIM:604059; AllianceGenome:HGNC:5200 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as 30ST4; 3OST4; 3-OST-4; h3-OST-4 Summary This gene encodes the enzyme heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4. This enzyme generates 3-O-sulfated glucosaminyl residues in heparan sulfate. Cell surface heparan sulfate is used as a receptor by herpes simplex virus type 1 (HSV-1), and expression of this gene is thought to play a role in HSV-1 pathogenesis. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 7.8), spleen (RPKM 1.0) and 1 other tissue See more Orthologs mouse all