ULK1, Official Symbol ULK1provided by HGNC Official Full Name unc-51 like autophagy activating kinase 1provided by HGNC Primary source HGNC:HGNC:12558 See related Ensembl:ENSG00000177169 MIM:603168; AllianceGenome:HGNC:12558 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATG1; ATG1A; UNC51; hATG1; Unc51.1 Summary Enables identical protein binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including autophagosome assembly; positive regulation by symbiont of host autophagy; and protein phosphorylation. Located in autophagosome; cytosol; and phagophore assembly site membrane. Is extrinsic component of autophagosome membrane; extrinsic component of omegasome membrane; and extrinsic component of phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in bone marrow (RPKM 14.9), endometrium (RPKM 11.7) and 25 other tissues See more Orthologs mouse all