CDKN3, Official Symbol CDKN3provided by HGNC Official Full Name cyclin dependent kinase inhibitor 3provided by HGNC Primary source HGNC:HGNC:1791 See related Ensembl:ENSG00000100526 MIM:123832; AllianceGenome:HGNC:1791 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KAP; CDI1; CIP2; KAP1 Summary The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] Expression Biased expression in testis (RPKM 79.3), bone marrow (RPKM 10.8) and 5 other tissues See more Orthologs mouse all