ABCC9, Official Symbol ABCC9provided by HGNC Official Full Name ATP binding cassette subfamily C member 9provided by HGNC Primary source HGNC:HGNC:60 See related Ensembl:ENSG00000069431 MIM:601439; AllianceGenome:HGNC:60 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SUR2; ABC37; CANTU; CMD1O; IDMYS; ATFB12 Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011] Expression Broad expression in fat (RPKM 12.5), liver (RPKM 7.3) and 19 other tissues See more Orthologs mouse all