OTX1, Official Symbol OTX1provided by HGNC Official Full Name orthodenticle homeobox 1provided by HGNC Primary source HGNC:HGNC:8521 See related Ensembl:ENSG00000115507 MIM:600036; AllianceGenome:HGNC:8521 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Expression Biased expression in skin (RPKM 2.2), prostate (RPKM 0.7) and 5 other tissues See more Orthologs mouse all