KDM1A, Official Symbol KDM1Aprovided by HGNC Official Full Name lysine demethylase 1Aprovided by HGNC Primary source HGNC:HGNC:29079 See related Ensembl:ENSG00000004487 MIM:609132; AllianceGenome:HGNC:29079 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as AOF2; CPRF; KDM1; LSD1; BHC110 Summary This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] Expression Broad expression in testis (RPKM 45.8), endometrium (RPKM 15.8) and 25 other tissues See more Orthologs mouse all