PHPT1, Official Symbol PHPT1provided by HGNC Official Full Name phosphohistidine phosphatase 1provided by HGNC Primary source HGNC:HGNC:30033 See related Ensembl:ENSG00000054148 MIM:610167; AllianceGenome:HGNC:30033 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PHP; PHP14; CGI-202; HSPC141; HEL-S-132P Summary This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] Expression Ubiquitous expression in heart (RPKM 26.6), prostate (RPKM 24.5) and 25 other tissues See more Orthologs mouse all