PHYKPL, Official Symbol PHYKPLprovided by HGNC Official Full Name 5-phosphohydroxy-L-lysine phospho-lyaseprovided by HGNC Primary source HGNC:HGNC:28249 See related Ensembl:ENSG00000175309 MIM:614683; AllianceGenome:HGNC:28249 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PHLU; AGXT2L2 Summary This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] Expression Ubiquitous expression in small intestine (RPKM 10.2), spleen (RPKM 9.1) and 25 other tissues See more Orthologs mouse all