GRIK5, Official Symbol GRIK5provided by HGNC Official Full Name glutamate ionotropic receptor kainate type subunit 5provided by HGNC Primary source HGNC:HGNC:4583 See related Ensembl:ENSG00000105737 MIM:600283; AllianceGenome:HGNC:4583 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as KA2; EAA2; GRIK2; GluK5 Summary This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Broad expression in testis (RPKM 5.6), brain (RPKM 5.5) and 14 other tissues See more Orthologs mouse all