C6, Official Symbol C6provided by HGNC Official Full Name complement C6provided by HGNC Primary source HGNC:HGNC:1339 See related Ensembl:ENSG00000039537 MIM:217050; AllianceGenome:HGNC:1339 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012] Expression Biased expression in liver (RPKM 126.4), heart (RPKM 11.8) and 2 other tissues See more Orthologs mouse all