BOK, Official Symbol BOKprovided by HGNC Official Full Name BCL2 family apoptosis regulator BOKprovided by HGNC Primary source HGNC:HGNC:1087 See related Ensembl:ENSG00000176720 MIM:605404; AllianceGenome:HGNC:1087 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BOKL; BCL2L9 Summary The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011] Expression Broad expression in fat (RPKM 69.1), liver (RPKM 18.4) and 16 other tissues See more Orthologs mouse all