CUL1, Official Symbol CUL1provided by HGNC Official Full Name cullin 1provided by HGNC Primary source HGNC:HGNC:2551 See related Ensembl:ENSG00000055130 MIM:603134; AllianceGenome:HGNC:2551 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Predicted to enable ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Located in plasma membrane. Part of Parkin-FBXW7-Cul1 ubiquitin ligase complex and SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in testis (RPKM 55.7), lymph node (RPKM 17.7) and 24 other tissues See more Orthologs mouse all