GSDME, Official Symbol GSDMEprovided by HGNC Official Full Name gasdermin Eprovided by HGNC Primary source HGNC:HGNC:2810 See related Ensembl:ENSG00000105928 MIM:608798; AllianceGenome:HGNC:2810 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DFNA5; ICERE-1 Summary Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in placenta (RPKM 18.9), small intestine (RPKM 11.1) and 19 other tissues See more Orthologs mouse all