FOSL1, Official Symbol FOSL1provided by HGNC Official Full Name FOS like 1, AP-1 transcription factor subunitprovided by HGNC Primary source HGNC:HGNC:13718 See related Ensembl:ENSG00000175592 MIM:136515; AllianceGenome:HGNC:13718 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FRA; FRA1; fra-1 Summary The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] Expression Biased expression in gall bladder (RPKM 16.7), urinary bladder (RPKM 10.2) and 13 other tissues See more Orthologs mouse all