CD6, Official Symbol CD6provided by HGNC Official Full Name CD6 moleculeprovided by HGNC Primary source HGNC:HGNC:1691 See related Ensembl:ENSG00000013725 MIM:186720; AllianceGenome:HGNC:1691 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TP120 Summary This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Expression Biased expression in lymph node (RPKM 22.7), appendix (RPKM 13.7) and 9 other tissues See more Orthologs mouse all