CENPO, Official Symbol CENPOprovided by HGNC Official Full Name centromere protein Oprovided by HGNC Primary source HGNC:HGNC:28152 See related Ensembl:ENSG00000138092 MIM:611504; AllianceGenome:HGNC:28152 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CENP-O; MCM21R; ICEN-36 Summary This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] Expression Ubiquitous expression in placenta (RPKM 11.4), testis (RPKM 8.5) and 24 other tissues See more Orthologs mouse all