CDH17, Official Symbol CDH17provided by HGNC Official Full Name cadherin 17provided by HGNC Primary source HGNC:HGNC:1756 See related Ensembl:ENSG00000079112 MIM:603017; AllianceGenome:HGNC:1756 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HPT1; CDH16; HPT-1 Summary This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] Expression Biased expression in duodenum (RPKM 145.2), small intestine (RPKM 127.8) and 2 other tissues See more Orthologs mouse all