PTGR2, Official Symbol PTGR2provided by HGNC Official Full Name prostaglandin reductase 2provided by HGNC Primary source HGNC:HGNC:20149 See related Ensembl:ENSG00000140043 MIM:608642; AllianceGenome:HGNC:20149 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PGR2; ZADH1; HEL-S-298 Summary This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] Expression Ubiquitous expression in heart (RPKM 10.6), thyroid (RPKM 9.3) and 24 other tissues See more Orthologs mouse all