SLC1A2, Official Symbol SLC1A2provided by HGNC Official Full Name solute carrier family 1 member 2provided by HGNC Primary source HGNC:HGNC:10940 See related Ensembl:ENSG00000110436 MIM:600300; AllianceGenome:HGNC:10940 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GLT1; HBGT; DEE41; EAAT2; GLT-1; EIEE41 Summary This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017] Expression Restricted expression toward brain (RPKM 153.3) See more Orthologs mouse all