NBEA, Official Symbol NBEAprovided by HGNC Official Full Name neurobeachinprovided by HGNC Primary source HGNC:HGNC:7648 See related Ensembl:ENSG00000172915 MIM:604889; AllianceGenome:HGNC:7648 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCL8B; LYST2; NEDEGE Summary This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011] Expression Broad expression in brain (RPKM 8.2), thyroid (RPKM 2.8) and 20 other tissues See more Orthologs mouse all