KCNN4, Official Symbol KCNN4provided by HGNC Official Full Name potassium calcium-activated channel subfamily N member 4provided by HGNC Primary source HGNC:HGNC:6293 See related Ensembl:ENSG00000104783 MIM:602754; AllianceGenome:HGNC:6293 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IK; IK1; SK4; DHS2; KCA4; hSK4; IKCA1; hKCa4; KCa3.1; hIKCa1 Summary The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008] Expression Biased expression in salivary gland (RPKM 25.8), stomach (RPKM 13.6) and 10 other tissues See more Orthologs mouse all