HNRNPH1, Official Symbol HNRNPH1provided by HGNC Official Full Name heterogeneous nuclear ribonucleoprotein H1provided by HGNC Primary source HGNC:HGNC:5041 See related Ensembl:ENSG00000169045 MIM:601035; AllianceGenome:HGNC:5041 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HNRPH; HNRPH1; NEDCDS; hnRNPH Summary This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012] Expression Ubiquitous expression in bone marrow (RPKM 153.8), lymph node (RPKM 101.7) and 25 other tissues See more Orthologs mouse all