DMRT2, Official Symbol DMRT2provided by HGNC Official Full Name doublesex and mab-3 related transcription factor 2provided by HGNC Primary source HGNC:HGNC:2935 See related Ensembl:ENSG00000173253 MIM:604935; AllianceGenome:HGNC:2935 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DSXL-2 Summary The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010] Expression Biased expression in kidney (RPKM 4.2), fat (RPKM 1.8) and 2 other tissues See more Orthologs mouse all