KMT5A, Official Symbol KMT5Aprovided by HGNC Official Full Name lysine methyltransferase 5Aprovided by HGNC Primary source HGNC:HGNC:29489 See related Ensembl:ENSG00000183955 MIM:607240; AllianceGenome:HGNC:29489 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SET8; SET07; SETD8; PR-Set7; PR/SET07 Summary The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation. [provided by RefSeq, May 2016] Expression Ubiquitous expression in prostate (RPKM 17.6), esophagus (RPKM 16.8) and 25 other tissues See more Orthologs mouse all