IGF2BP1, Official Symbol IGF2BP1provided by HGNC Official Full Name insulin like growth factor 2 mRNA binding protein 1provided by HGNC Primary source HGNC:HGNC:28866 See related Ensembl:ENSG00000159217 MIM:608288; AllianceGenome:HGNC:28866 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1 Summary This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Annotation information Note: ZBP1 (GeneID: 81030) and IGF2BP1 (GeneID:10642) share the ZBP1 symbol/alias in common. ZBP1 is a widely used alternative name for insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1), which can be confused with the official symbol for ZBP1, Z-DNA binding protein 1 (ZBP1). [09 Aug 2021] Expression Biased expression in testis (RPKM 3.6), placenta (RPKM 2.9) and 1 other tissue See more Orthologs mouse all