GPR27, Official Symbol GPR27provided by HGNC Official Full Name G protein-coupled receptor 27provided by HGNC Primary source HGNC:HGNC:4482 See related Ensembl:ENSG00000170837 MIM:605187; AllianceGenome:HGNC:4482 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SREB1 Summary GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010] Orthologs mouse all