ING4, Official Symbol ING4provided by HGNC Official Full Name inhibitor of growth family member 4provided by HGNC Primary source HGNC:HGNC:19423 See related Ensembl:ENSG00000111653 MIM:608524; AllianceGenome:HGNC:19423 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as my036; p29ING4 Summary This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 15.7), endometrium (RPKM 14.9) and 25 other tissues See more Orthologs mouse all