SMO, Official Symbol SMOprovided by HGNC Official Full Name smoothened, frizzled class receptorprovided by HGNC Primary source HGNC:HGNC:11119 See related Ensembl:ENSG00000128602 MIM:601500; AllianceGenome:HGNC:11119 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as Gx; CRJS; PHLS; SMOH; FZD11 Summary The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010] Expression Broad expression in ovary (RPKM 15.6), endometrium (RPKM 13.9) and 24 other tissues See more Orthologs mouse all