SLITRK1, Official Symbol SLITRK1provided by HGNC Official Full Name SLIT and NTRK like family member 1provided by HGNC Primary source HGNC:HGNC:20297 See related Ensembl:ENSG00000178235 MIM:609678; AllianceGenome:HGNC:20297 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as TTM; LRRC12 Summary This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology to neurotrophin receptors. This protein is thought to be involved in neurite outgrowth. Mutations in this gene may be associated with Tourette syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Restricted expression toward brain (RPKM 10.6) See more Orthologs mouse all