UBA2, Official Symbol UBA2provided by HGNC Official Full Name ubiquitin like modifier activating enzyme 2provided by HGNC Primary source HGNC:HGNC:30661 See related Ensembl:ENSG00000126261 MIM:613295; AllianceGenome:HGNC:30661 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ARX; SAE2; ACCES; HRIHFB2115 Summary Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] Expression Ubiquitous expression in testis (RPKM 52.1), fat (RPKM 42.8) and 25 other tissues See more Orthologs mouse all