ANAPC1, Official Symbol ANAPC1provided by HGNC Official Full Name anaphase promoting complex subunit 1provided by HGNC Primary source HGNC:HGNC:19988 See related Ensembl:ENSG00000153107 MIM:608473; AllianceGenome:HGNC:19988 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APC1; MCPR; TSG24 Summary This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011] Expression Ubiquitous expression in testis (RPKM 7.2), lymph node (RPKM 6.5) and 25 other tissues See more Orthologs mouse all