RIPOR2, Official Symbol RIPOR2provided by HGNC Official Full Name RHO family interacting cell polarization regulator 2provided by HGNC Primary source HGNC:HGNC:13872 See related Ensembl:ENSG00000111913 MIM:611410; AllianceGenome:HGNC:13872 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PL48; DFNA21; DIFF40; DIFF48; FAM65B; MYONAP; C6orf32; DFNB104 Summary This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. [provided by RefSeq, Sep 2016] Expression Biased expression in lymph node (RPKM 23.2), spleen (RPKM 16.0) and 11 other tissues See more Orthologs mouse all