HGFAC, Official Symbol HGFACprovided by HGNC Official Full Name HGF activatorprovided by HGNC Primary source HGNC:HGNC:4894 See related Ensembl:ENSG00000109758 MIM:604552; AllianceGenome:HGNC:4894 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HGFA Summary This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Restricted expression toward liver (RPKM 27.9) See more Orthologs mouse all