RGS20, Official Symbol RGS20provided by HGNC Official Full Name regulator of G protein signaling 20provided by HGNC Primary source HGNC:HGNC:14600 See related Ensembl:ENSG00000147509 MIM:607193; AllianceGenome:HGNC:14600 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RGSZ1; ZGAP1; gz-GAP; g(z)GAP Summary The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Expression Biased expression in brain (RPKM 2.5), thyroid (RPKM 0.6) and 3 other tissues See more Orthologs mouse all