NCKAP1, Official Symbol NCKAP1provided by HGNC Official Full Name NCK associated protein 1provided by HGNC Primary source HGNC:HGNC:7666 See related Ensembl:ENSG00000061676 MIM:604891; AllianceGenome:HGNC:7666 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HEM2; NAP1; NAP125; p125Nap1 Summary Contributes to small GTPase binding activity. Involved in Rac protein signal transduction; positive regulation of Arp2/3 complex-mediated actin nucleation; and positive regulation of lamellipodium assembly. Located in extracellular exosome and focal adhesion. Part of SCAR complex. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in thyroid (RPKM 62.7), brain (RPKM 61.6) and 24 other tissues See more Orthologs mouse all