TLN2, Official Symbol TLN2provided by HGNC Official Full Name talin 2provided by HGNC Primary source HGNC:HGNC:15447 See related Ensembl:ENSG00000171914 MIM:607349; AllianceGenome:HGNC:15447 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ILWEQ Summary This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008] Expression Broad expression in kidney (RPKM 12.9), brain (RPKM 11.8) and 19 other tissues See more Orthologs mouse all