PRRX2, Official Symbol PRRX2provided by HGNC Official Full Name paired related homeobox 2provided by HGNC Primary source HGNC:HGNC:21338 See related Ensembl:ENSG00000167157 MIM:604675; AllianceGenome:HGNC:21338 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PMX2; PRX2 Summary The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008] Expression Broad expression in skin (RPKM 3.1), prostate (RPKM 3.0) and 17 other tissues See more Orthologs mouse all