CACNG1, Official Symbol CACNG1provided by HGNC Official Full Name calcium voltage-gated channel auxiliary subunit gamma 1provided by HGNC Primary source HGNC:HGNC:1405 See related Ensembl:ENSG00000108878 MIM:114209; AllianceGenome:HGNC:1405 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CACNLG Summary Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). [provided by RefSeq, Dec 2010] Expression Biased expression in esophagus (RPKM 1.9), prostate (RPKM 1.8) and 2 other tissues See more Orthologs mouse all