PIK3C3, Official Symbol PIK3C3provided by HGNC Official Full Name phosphatidylinositol 3-kinase catalytic subunit type 3provided by HGNC Primary source HGNC:HGNC:8974 See related Ensembl:ENSG00000078142 MIM:602609; AllianceGenome:HGNC:8974 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as VPS34; Vps34; hVps34 Summary Enables 1-phosphatidylinositol-3-kinase activity. Involved in early endosome to late endosome transport and regulation of cytokinesis. Acts upstream of or within autophagy and protein lipidation. Located in autolysosome; late endosome; and midbody. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in testis (RPKM 7.2), brain (RPKM 7.0) and 25 other tissues See more Orthologs mouse all