SIX1, Official Symbol SIX1provided by HGNC Official Full Name SIX homeobox 1provided by HGNC Primary source HGNC:HGNC:10887 See related Ensembl:ENSG00000126778 MIM:601205; AllianceGenome:HGNC:10887 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BOS3; TIP39; DFNA23 Summary The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3). [provided by RefSeq, Jul 2008] Expression Biased expression in salivary gland (RPKM 12.9), prostate (RPKM 9.2) and 6 other tissues See more Orthologs mouse all