DPM3, Official Symbol DPM3provided by HGNC Official Full Name dolichyl-phosphate mannosyltransferase subunit 3, regulatoryprovided by HGNC Primary source HGNC:HGNC:3007 See related Ensembl:ENSG00000179085 MIM:605951; AllianceGenome:HGNC:3007 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CDG1O; MDDGB15; MDDGC15 Summary Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in fat (RPKM 20.5), colon (RPKM 20.2) and 25 other tissues See more Orthologs mouse all