URI1, Official Symbol URI1provided by HGNC Official Full Name URI1 prefoldin like chaperoneprovided by HGNC Primary source HGNC:HGNC:13236 See related Ensembl:ENSG00000105176 MIM:603494; AllianceGenome:HGNC:13236 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RMP; URI; NNX3; C19orf2; PPP1R19 Summary This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. [provided by RefSeq, Nov 2011] Expression Ubiquitous expression in thyroid (RPKM 23.9), testis (RPKM 18.7) and 25 other tissues See more Orthologs mouse all