UTF1, Official Symbol UTF1provided by HGNC Official Full Name undifferentiated embryonic cell transcription factor 1provided by HGNC Primary source HGNC:HGNC:12634 See related Ensembl:ENSG00000171794 MIM:604130; AllianceGenome:HGNC:12634 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene is a leucine zipper-containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. Found nearly exclusively in pluripotent cells, this protein can also serve as a transcriptional repressor. [provided by RefSeq, Nov 2015] Expression Low expression observed in reference dataset See more Orthologs mouse all