CA7, Official Symbol CA7provided by HGNC Official Full Name carbonic anhydrase 7provided by HGNC Primary source HGNC:HGNC:1381 See related Ensembl:ENSG00000168748 MIM:114770; AllianceGenome:HGNC:1381 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CAVII; CA-VII Summary Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018] Expression Biased expression in colon (RPKM 16.2), small intestine (RPKM 3.6) and 2 other tissues See more Orthologs mouse all