DENND2D, Official Symbol DENND2Dprovided by HGNC Official Full Name DENN domain containing 2Dprovided by HGNC Primary source HGNC:HGNC:26192 See related Ensembl:ENSG00000162777 MIM:615111; AllianceGenome:HGNC:26192 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in lymph node (RPKM 32.5), appendix (RPKM 17.0) and 20 other tissues See more Orthologs mouse all