DHDDS, Official Symbol DHDDSprovided by HGNC Official Full Name dehydrodolichyl diphosphate synthase subunitprovided by HGNC Primary source HGNC:HGNC:20603 See related Ensembl:ENSG00000117682 MIM:608172; AllianceGenome:HGNC:20603 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as DS; CIT; CPT; HDS; RP59; hCIT; DEDSM Summary The protein encoded by this gene catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins. Mutations in this gene are associated with retinitis pigmentosa type 59. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] Expression Ubiquitous expression in fat (RPKM 22.0), colon (RPKM 11.7) and 24 other tissues See more Orthologs mouse all