SMG1, Official Symbol SMG1provided by HGNC Official Full Name SMG1 nonsense mediated mRNA decay associated PI3K related kinaseprovided by HGNC Primary source HGNC:HGNC:30045 See related Ensembl:ENSG00000157106 MIM:607032; AllianceGenome:HGNC:30045 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ATX; LIP; 61E3.4 Summary This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013] Expression Ubiquitous expression in skin (RPKM 20.7), bone marrow (RPKM 12.3) and 25 other tissues See more Orthologs mouse all