FHL5, Official Symbol FHL5provided by HGNC Official Full Name four and a half LIM domains 5provided by HGNC Primary source HGNC:HGNC:17371 See related Ensembl:ENSG00000112214 MIM:605126; AllianceGenome:HGNC:17371 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ACT; FHL-5; dJ393D12.2; 1700027G07Rik Summary The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Polymorphisms in this gene may be associated with susceptibility for migraine headaches. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Apr 2016] Expression Broad expression in testis (RPKM 16.0), fat (RPKM 12.3) and 18 other tissues See more Orthologs mouse all