KCNJ2, Official Symbol KCNJ2provided by HGNC Official Full Name potassium inwardly rectifying channel subfamily J member 2provided by HGNC Primary source HGNC:HGNC:6263 See related Ensembl:ENSG00000123700 MIM:600681; AllianceGenome:HGNC:6263 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as IRK1; LQT7; SQT3; ATFB9; HHIRK1; KIR2.1; HHBIRK1 Summary Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008] Expression Broad expression in spleen (RPKM 3.4), heart (RPKM 3.3) and 23 other tissues See more Orthologs mouse all