SYTL2, Official Symbol SYTL2provided by HGNC Official Full Name synaptotagmin like 2provided by HGNC Primary source HGNC:HGNC:15585 See related Ensembl:ENSG00000137501 MIM:612880; AllianceGenome:HGNC:15585 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as EXO4; SLP2; SLP2A; SGA72M; CHR11SYT; PPP1R151 Summary The protein encoded by this gene is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jun 2009] Expression Broad expression in stomach (RPKM 22.4), colon (RPKM 16.3) and 17 other tissues See more Orthologs mouse all