MAD2L2, Official Symbol MAD2L2provided by HGNC Official Full Name mitotic arrest deficient 2 like 2provided by HGNC Primary source HGNC:HGNC:6764 See related Ensembl:ENSG00000116670 MIM:604094; AllianceGenome:HGNC:6764 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as REV7; FANCV; MAD2B; POLZ2 Summary The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 22.7), bone marrow (RPKM 15.4) and 25 other tissues See more Orthologs mouse all