ST3GAL5, Official Symbol ST3GAL5provided by HGNC Official Full Name ST3 beta-galactoside alpha-2,3-sialyltransferase 5provided by HGNC Primary source HGNC:HGNC:10872 See related Ensembl:ENSG00000115525 MIM:604402; AllianceGenome:HGNC:10872 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as SATI; SIAT9; SPDRS; ST3GalV; SIATGM3S; ST3Gal V Summary Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Expression Broad expression in adrenal (RPKM 17.6), thyroid (RPKM 16.1) and 23 other tissues See more Orthologs mouse all