MARS2, Official Symbol MARS2provided by HGNC Official Full Name methionyl-tRNA synthetase 2, mitochondrialprovided by HGNC Primary source HGNC:HGNC:25133 See related Ensembl:ENSG00000247626 MIM:609728; AllianceGenome:HGNC:25133 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MetRS; COXPD25; mtMetRS Summary This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014] Orthologs mouse all