RUVBL2, Official Symbol RUVBL2provided by HGNC Official Full Name RuvB like AAA ATPase 2provided by HGNC Primary source HGNC:HGNC:10475 See related Ensembl:ENSG00000183207 MIM:604788; AllianceGenome:HGNC:10475 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as RVB2; TIH2; ECP51; TIP48; CGI-46; ECP-51; INO80J; REPTIN; TIP49B; TAP54-beta Summary This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008] Expression Broad expression in testis (RPKM 64.1), colon (RPKM 12.0) and 24 other tissues See more Orthologs mouse all