EDA2R, Official Symbol EDA2Rprovided by HGNC Official Full Name ectodysplasin A2 receptorprovided by HGNC Primary source HGNC:HGNC:17756 See related Ensembl:ENSG00000131080 MIM:300276; AllianceGenome:HGNC:17756 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as XEDAR; EDAA2R; EDA-A2R; TNFRSF27 Summary The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016] Expression Broad expression in thyroid (RPKM 3.4), ovary (RPKM 3.3) and 22 other tissues See more Orthologs mouse all