PABPC5, Official Symbol PABPC5provided by HGNC Official Full Name poly(A) binding protein cytoplasmic 5provided by HGNC Primary source HGNC:HGNC:13629 See related Ensembl:ENSG00000174740 MIM:300407; AllianceGenome:HGNC:13629 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PABP5 Summary This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010] Expression Broad expression in ovary (RPKM 5.4), adrenal (RPKM 4.2) and 18 other tissues See more Orthologs mouse all