NPRL2, Official Symbol NPRL2provided by HGNC Official Full Name NPR2 like, GATOR1 complex subunitprovided by HGNC Primary source HGNC:HGNC:24969 See related Ensembl:ENSG00000114388 MIM:607072; AllianceGenome:HGNC:24969 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NPR2; NPR2L; TUSC4; FFEVF2 Summary Enables protein kinase activity. Contributes to GTPase activator activity. Involved in cellular response to amino acid starvation; negative regulation of TOR signaling; and negative regulation of kinase activity. Located in lysosomal membrane. Part of GATOR1 complex. Implicated in focal epilepsy. [provided by Alliance of Genome Resources, Apr 2022] Expression Ubiquitous expression in lymph node (RPKM 7.6), ovary (RPKM 7.3) and 25 other tissues See more Orthologs mouse all