TNIK, Official Symbol TNIKprovided by HGNC Official Full Name TRAF2 and NCK interacting kinaseprovided by HGNC Primary source HGNC:HGNC:30765 See related Ensembl:ENSG00000154310 MIM:610005; AllianceGenome:HGNC:30765 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MRT54 Summary Wnt signaling plays important roles in carcinogenesis and embryonic development. The protein encoded by this gene is a serine/threonine kinase that functions as an activator of the Wnt signaling pathway. Mutations in this gene are associated with an autosomal recessive form of cognitive disability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017] Expression Broad expression in brain (RPKM 10.5), small intestine (RPKM 7.1) and 20 other tissues See more Orthologs mouse all