KAT7, Official Symbol KAT7provided by HGNC Official Full Name lysine acetyltransferase 7provided by HGNC Primary source HGNC:HGNC:17016 See related Ensembl:ENSG00000136504 MIM:609880; AllianceGenome:HGNC:17016 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as HBO1; HBOA; MYST2; ZC2HC7 Summary The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016] Expression Broad expression in testis (RPKM 37.1), bone marrow (RPKM 22.8) and 24 other tissues See more Orthologs mouse all