TEC, Official Symbol TECprovided by HGNC Official Full Name tec protein tyrosine kinaseprovided by HGNC Primary source HGNC:HGNC:11719 See related Ensembl:ENSG00000135605 MIM:600583; AllianceGenome:HGNC:11719 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PSCTK4 Summary The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in bone marrow (RPKM 2.4), esophagus (RPKM 1.4) and 23 other tissues See more Orthologs mouse all