SLC4A7, Official Symbol SLC4A7provided by HGNC Official Full Name solute carrier family 4 member 7provided by HGNC Primary source HGNC:HGNC:11033 See related Ensembl:ENSG00000033867 MIM:603353; AllianceGenome:HGNC:11033 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as NBC2; NBC3; SBC2; NBCN1; SLC4A6 Summary This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012] Expression Ubiquitous expression in duodenum (RPKM 27.5), small intestine (RPKM 8.8) and 20 other tissues See more Orthologs mouse all