CXCL1, Official Symbol CXCL1provided by HGNC Official Full Name C-X-C motif chemokine ligand 1provided by HGNC Primary source HGNC:HGNC:4602 See related Ensembl:ENSG00000163739 MIM:155730; AllianceGenome:HGNC:4602 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a Summary This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014] Annotation information Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in immune response or antiviral activity. Expression Biased expression in spleen (RPKM 42.1), urinary bladder (RPKM 38.5) and 12 other tissues See more Orthologs all