TNFRSF17, Official Symbol TNFRSF17provided by HGNC Official Full Name TNF receptor superfamily member 17provided by HGNC Primary source HGNC:HGNC:11913 See related Ensembl:ENSG00000048462 MIM:109545; AllianceGenome:HGNC:11913 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as BCM; BCMA; CD269; TNFRSF13A Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] Expression Biased expression in lymph node (RPKM 11.9), duodenum (RPKM 11.5) and 10 other tissues See more Orthologs mouse all