FBXO17, Official Symbol FBXO17provided by HGNC Official Full Name F-box protein 17provided by HGNC Primary source HGNC:HGNC:18754 See related Ensembl:ENSG00000269190 MIM:609094; AllianceGenome:HGNC:18754 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBG4; FBX26; Fbx17; FBXO26 Summary This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] Expression Broad expression in kidney (RPKM 11.1), ovary (RPKM 9.9) and 23 other tissues See more Orthologs mouse all