GMPR, Official Symbol GMPRprovided by HGNC Official Full Name guanosine monophosphate reductaseprovided by HGNC Primary source HGNC:HGNC:4376 See related Ensembl:ENSG00000137198 MIM:139265; AllianceGenome:HGNC:4376 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GMPR1; GMPR 1 Summary This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009] Expression Broad expression in prostate (RPKM 33.0), testis (RPKM 29.5) and 19 other tissues See more Orthologs mouse all