ASB6, Official Symbol ASB6provided by HGNC Official Full Name ankyrin repeat and SOCS box containing 6provided by HGNC Primary source HGNC:HGNC:17181 See related Ensembl:ENSG00000148331 MIM:615051; AllianceGenome:HGNC:17181 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011] Expression Ubiquitous expression in testis (RPKM 8.1), bone marrow (RPKM 7.8) and 25 other tissues See more Orthologs mouse all