TSEN54, Official Symbol TSEN54provided by HGNC Official Full Name tRNA splicing endonuclease subunit 54provided by HGNC Primary source HGNC:HGNC:27561 See related Ensembl:ENSG00000182173 MIM:608755; AllianceGenome:HGNC:27561 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PCH4; PCH5; PCH2A; sen54; SEN54L Summary This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.[provided by RefSeq, Oct 2009] Expression Ubiquitous expression in spleen (RPKM 8.3), duodenum (RPKM 7.0) and 25 other tissues See more Orthologs mouse all