CORIN, Official Symbol CORINprovided by HGNC Official Full Name corin, serine peptidaseprovided by HGNC Primary source HGNC:HGNC:19012 See related Ensembl:ENSG00000145244 MIM:605236; AllianceGenome:HGNC:19012 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CRN; ATC2; Lrp4; PEE5; TMPRSS10 Summary This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013] Expression Biased expression in heart (RPKM 20.5), skin (RPKM 3.4) and 2 other tissues See more Orthologs mouse all