LHX6, Official Symbol LHX6provided by HGNC Official Full Name LIM homeobox 6provided by HGNC Primary source HGNC:HGNC:21735 See related Ensembl:ENSG00000106852 MIM:608215; AllianceGenome:HGNC:21735 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as hLHX6; LHX6.1 Summary This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein has tandem LIM domains as well as a DNA-binding homeodomain. The protein functions as a transcription factor involved in embryogenesis and head development and is highly expressed in neural crest derived mesenchyme cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2017] Expression Broad expression in fat (RPKM 1.9), brain (RPKM 1.8) and 20 other tissues See more Orthologs mouse all