NHS, Official Symbol NHSprovided by HGNC Official Full Name NHS actin remodeling regulatorprovided by HGNC Primary source HGNC:HGNC:7820 See related Ensembl:ENSG00000188158 MIM:300457; AllianceGenome:HGNC:7820 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CXN; SCML1; CTRCT40 Summary This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein functions in eye, tooth, craniofacial and brain development, and it can regulate actin remodeling and cell morphology. Mutations in this gene have been shown to cause Nance-Horan syndrome, and also X-linked cataract-40. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2014] Expression Broad expression in endometrium (RPKM 2.8), kidney (RPKM 2.8) and 22 other tissues See more Orthologs mouse all