FBXO41, Official Symbol FBXO41provided by HGNC Official Full Name F-box protein 41provided by HGNC Primary source HGNC:HGNC:29409 See related Ensembl:ENSG00000163013 MIM:609108; AllianceGenome:HGNC:29409 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as FBX41 Summary This gene encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the SCF ubiquitin protein ligase complex that plays a role in phosphorylation-dependent ubiquitination. F-box proteins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains, FBXL proteins contain leucine-rich repeats, and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the FBXO class. [provided by RefSeq, Feb 2014] Expression Biased expression in brain (RPKM 10.6), lymph node (RPKM 3.0) and 13 other tissues See more Orthologs mouse all