SPEF1, Official Symbol SPEF1provided by HGNC Official Full Name sperm flagellar 1provided by HGNC Primary source HGNC:HGNC:15874 See related Ensembl:ENSG00000101222 MIM:610674; AllianceGenome:HGNC:15874 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as CLAMP; SPEF1A; C20orf28 Summary Enables actin binding activity. Involved in filopodium assembly; lamellipodium assembly; and negative regulation of cell death. Located in several cellular components, including basolateral plasma membrane; lamellipodium; and microvillus. [provided by Alliance of Genome Resources, Apr 2022] Expression Biased expression in testis (RPKM 4.6), brain (RPKM 1.1) and 4 other tissues See more Orthologs mouse all