ERC1, Official Symbol ERC1provided by HGNC Official Full Name ELKS/RAB6-interacting/CAST family member 1provided by HGNC Primary source HGNC:HGNC:17072 See related Ensembl:ENSG00000082805 MIM:607127; AllianceGenome:HGNC:17072 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ELKS; Cast2; ERC-1; RAB6IP2 Summary The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Expression Ubiquitous expression in thyroid (RPKM 7.0), esophagus (RPKM 6.1) and 25 other tissues See more Orthologs mouse all