CBX4, Official Symbol CBX4provided by HGNC Official Full Name chromobox 4provided by HGNC Primary source HGNC:HGNC:1554 See related Ensembl:ENSG00000141582 MIM:603079; AllianceGenome:HGNC:1554 Gene type protein coding RefSeq status VALIDATED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PC2; NBP16 Summary Enables SUMO binding activity; SUMO ligase activity; and enzyme binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nuclear body. Part of PRC1 complex. Implicated in hepatocellular carcinoma. Biomarker of hepatocellular carcinoma. [provided by Alliance of Genome Resources, Apr 2022] Expression Broad expression in bone marrow (RPKM 17.4), spleen (RPKM 5.9) and 24 other tissues See more Orthologs mouse all