YWHAH, Official Symbol YWHAHprovided by HGNC Official Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein etaprovided by HGNC Primary source HGNC:HGNC:12853 See related Ensembl:ENSG00000128245 MIM:113508; AllianceGenome:HGNC:12853 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as YWHA1 Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009] Expression Broad expression in brain (RPKM 343.5), lung (RPKM 62.6) and 22 other tissues See more Orthologs mouse all