LCAT, Official Symbol LCATprovided by HGNC Official Full Name lecithin-cholesterol acyltransferaseprovided by HGNC Primary source HGNC:HGNC:6522 See related Ensembl:ENSG00000213398 MIM:606967; AllianceGenome:HGNC:6522 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency. [provided by RefSeq, Jul 2008] Expression Broad expression in liver (RPKM 51.1), skin (RPKM 11.1) and 19 other tissues See more Orthologs mouse all