SRPRB, Official Symbol SRPRBprovided by HGNC Official Full Name SRP receptor subunit betaprovided by HGNC Primary source HGNC:HGNC:24085 See related Ensembl:ENSG00000144867 MIM:616883; AllianceGenome:HGNC:24085 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as APMCF1; SR-beta Summary The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane. [provided by RefSeq, Jul 2008] Expression Ubiquitous expression in thyroid (RPKM 18.4), testis (RPKM 17.1) and 25 other tissues See more Orthologs mouse all