HEPACAM2, Official Symbol HEPACAM2provided by HGNC Official Full Name HEPACAM family member 2provided by HGNC Primary source HGNC:HGNC:27364 See related Ensembl:ENSG00000188175 MIM:614133; AllianceGenome:HGNC:27364 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as MIKI Summary This gene encodes a protein related to the immunoglobulin superfamily that plays a role in mitosis. Knockdown of this gene results in prometaphase arrest, abnormal nuclear morphology and apoptosis. Poly(ADP-ribosylation) of the encoded protein promotes its translocation to centrosomes, which may stimulate centrosome maturation. A chromosomal deletion including this gene may be associated with myeloid leukemia and myelodysplastic syndrome in human patients. [provided by RefSeq, Oct 2016] Expression Biased expression in colon (RPKM 38.5), small intestine (RPKM 21.6) and 3 other tissues See more Orthologs mouse all