TM4SF4, Official Symbol TM4SF4provided by HGNC Official Full Name transmembrane 4 L six family member 4provided by HGNC Primary source HGNC:HGNC:11856 See related Ensembl:ENSG00000169903 MIM:606567; AllianceGenome:HGNC:11856 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as ILTMP; il-TMP Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation.[provided by RefSeq, Mar 2011] Expression Biased expression in gall bladder (RPKM 554.1), duodenum (RPKM 308.9) and 2 other tissues See more Orthologs mouse all