DRD1, Official Symbol DRD1provided by HGNC Official Full Name dopamine receptor D1provided by HGNC Primary source HGNC:HGNC:3020 See related Ensembl:ENSG00000184845 MIM:126449; AllianceGenome:HGNC:3020 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as D1R; DADR; DRD1A Summary This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008] Expression Biased expression in brain (RPKM 3.4), placenta (RPKM 0.8) and 9 other tissues See more Orthologs mouse all