OXCT1, Official Symbol OXCT1provided by HGNC Official Full Name 3-oxoacid CoA-transferase 1provided by HGNC Primary source HGNC:HGNC:8527 See related Ensembl:ENSG00000083720 MIM:601424; AllianceGenome:HGNC:8527 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as OXCT; SCOT Summary This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008] Expression Broad expression in heart (RPKM 90.1), brain (RPKM 37.8) and 19 other tissues See more Orthologs mouse all