PBX4, Official Symbol PBX4provided by HGNC Official Full Name PBX homeobox 4provided by HGNC Primary source HGNC:HGNC:13403 See related Ensembl:ENSG00000105717 MIM:608127; AllianceGenome:HGNC:13403 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Summary This gene encodes a member of the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011] Expression Broad expression in thyroid (RPKM 3.9), testis (RPKM 2.5) and 18 other tissues See more Orthologs mouse all