PRUNE1, Official Symbol PRUNE1provided by HGNC Official Full Name prune exopolyphosphatase 1provided by HGNC Primary source HGNC:HGNC:13420 See related Ensembl:ENSG00000143363 MIM:617413; AllianceGenome:HGNC:13420 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as PRUNE; DRES17; HTCD37; NMIHBA; DRES-17; H-PRUNE Summary This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] Expression Ubiquitous expression in thyroid (RPKM 21.1), heart (RPKM 13.3) and 25 other tissues See more Orthologs mouse all