ST8SIA1, Official Symbol ST8SIA1provided by HGNC Official Full Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1provided by HGNC Primary source HGNC:HGNC:10869 See related Ensembl:ENSG00000111728 MIM:601123; AllianceGenome:HGNC:10869 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo Also known as GD3S; SIAT8; SIAT8A; SIAT8-A; ST8SiaI Summary Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015] Expression Broad expression in brain (RPKM 1.5), adrenal (RPKM 0.7) and 19 other tissues See more Orthologs mouse all