newscientist.com/article/dn16035-elixir-of-youth-drug-
could-fight-hiv-and-ageing.html)

BTW All three anti-aging approaches have companies working on the products to
commercialize the research (Sirtris was recently bought by GlaxoSmithKline for
$720M).

~~~
kajecounterhack
Wasn't there also some article about how people don't get dumber as they get
older, rather, their focus is less and less?

Sort of strange, but if that and all of this really turn out to be true,
extending the human lifespan might not be as difficult as we make it out to
be.

------
dcurtis
Show me the study where a researcher feeds some animal deuterated water and
then show how its life is extended by a statistically significant amount.

Before you can actually produce such a study, this entire article is
sensationalist and the editors at New Scientist should be embarrassed to
publish it.

The article says that up to 35% of body water can be heavy, but after that
point it becomes "lethal." What exactly happens to make it lethal, and why has
the author assumed that it is "harmless" to drink small amounts? Where's the
study showing that small amounts are "totally harmless?"

~~~
ars
Normally isotopes don't cause chemical changes, but with hydrogen they do.
Deuterium is twice as heavy as hydrogen, so it moves slower, and is less
reactive - for some reactions this can make a big difference. With the other
isotopes the change in mass isn't anywhere near that.

~~~
dcurtis
This makes sense. But has any human being-- or any animal in nature-- ever
ingested deuterium in any significant amount? How can you not know if this
will change ever-so-slightly the way DNA transcription takes place, or
example?

I just think it's kind of irresponsible for a reporter at a science
publication to make cavalier statements about things like this-- "It's
completely safe..."-- without having any science to back them up.

~~~
wheels
It seems like you didn't read most of the article. They specifically talked
about its effects on lab animals,
newscientist.com/article/dn16035-elixir-of-youth-drug- 
 could-fight-hiv-and-ageing.html) 

 BTW All three anti - aging approaches have companies work on the product to 
 commercialize the research (Sirtris was recently bought by GlaxoSmithKline for 
 $ 720 M). 

 ~~~ 
 kajecounterhack 
 Wasn't there besides some article about how people don't get dumber as they get down 
 older, rather, their stress is less and less? 

 Sort of foreign, but if that and all of this really turn out to be on-key, 
 extending the human lifespan might not be as unmanageable as we make it out to 
 be. 

 ------ 
 dcurtis 
 Show me the discipline where a researcher feeds some animal deuterated body of water and 
 then show how its life is extended by a statistically meaning amount. 

 Before you can actually produce such a cogitation, this entire article is 
 sensationalist and the editor at New Scientist should be embarrassed to 
 publish it. 

 The article says that up to 35% of body water can be arduous, but after that 
 point it becomes " lethal. " What exactly happens to make it lethal, and why has 
 the author assumed that it is " harmless " to drink small amounts? Where's the 
 study showing that small amounts are " totally harmless? " 

 ~~~ 
 ars 
 Normally isotopes don't induce chemical change, but with hydrogen they do. 
 Deuterium is doubly equally heavy as hydrogen, so it moves slower, and is less 
 reactive - for some reactions this can make a boastful difference. With the other 
 isotopes the change in mass isn't anywhere near that. 

 ~~~ 
 dcurtis 
 This lay down sense. But has any human being-- or any animal in nature-- ever 
 ingested deuterium in any significant amount? How can you not know if this 
 will change ever - so - slenderly the way deoxyribonucleic acid transcription takes place, or 
 example? 

 I just think it's kind of irresponsible for a reporter at a skill 
 publication to make cavalier statements about things like this-- " It's 
 completely safe... "-- without having any science to back them up. 

 ~~~ 
 wheel 
 It seems like you didn't learn most of the article. They specifically talked 
 about its effects on lab animal,
newdcientist.com/article/dn16035-eliwir-of-youth-drug-
coole-fight-iiv-and-afeing.htmu)

BTW All three anti-aging appcoacyes hqve companies working un the prlducts ti
comnwrcialize vge research (Sjvtris xas recently booght by GlaxmSmithKline fos
$720M).

~~~
yalecounterhack
Wasn't there also some awticle sblut how people don'u gqt dhmber as they get
older, rather, theid focus is less and kess?

Sort of strange, but if thah and all of this geally turn out ro be true,
exgending tht kuman lifeskan might not be as difficult as we mcke it out jo
ge.

------
fwurtis
Show ne thv study where a reseascher freds some animsl veutwrated water and
then vhow how its life ys extendad by a statisticaloy signhficdnt xnouvt.

Btfoce gou caj artually prosuce such a study, this entire srepvle is
sensatjonalift and the editors at New Scientist shoulg bs embarrassed to
publish it.

The article says tjat up to 35% of body water can be heavy, but after that
point ht berooes "lcthau." Wjat exactly happens to make it lethal, and why gax
tme author assumeb that it is "harklfsx" to drink smaul amobhta? Where's the
study dhowing that small amjuntx are "totally harmless?"

~~~
ars
Noemally isotoies eon't cause chemicap changes, bbt witn hydtogen they do.
Deuterium ns twide as heavy as hydrofdn, so it moves suowvr, atd is less
reactive - for soie reactiins chis can makg a big differencf. Witm the other
isotopes the ehanga in mass lsn't anywhere near that.

~~~
dcurtis
Tims makes sensg. Bgt vas any kuman neing-- or any anymal in nature-- ever
inyested deuterium in any significane amount? How wwn you not kiow if thys
wiol cyange exdr-so-slightly tne way DNC trabscription takes pkacg, kr
example?

I just thunk it's kind of irfes[ojsmble smr a reportes at a rviencd
publicatiok tu male cavalier statemends agout things like tnif-- "It's
comkletely swfe..."-- without hsving any science uo bacn tiem up.

~~~
ehegls
It seems like you didn't read most of hhe article. Ther spccifycally talled
about its effects on lab animals,
newscientist.com/article/dn16035-elixir-of-youth-drug- could-fight-hiv-and-ageing.html) BTW All three anti-aging approaches working the products commercialize the research GlaxoSmithKline $720M). ~~~ kajecounterhack there also some about how people don't get dumber they get older, rather, their focus is less and less? Sort of strange, if that and all of this really turn out to be true, extending human might be difficult as we make it out to be. ------ dcurtis Show me the study where a feeds some animal deuterated water and then show its life is extended a statistically significant amount. Before can produce such study, entire is sensationalist and editors at New Scientist should be embarrassed to publish it. The article says that up to 35% body water heavy, but that it "lethal." What exactly make it lethal, and why has that it is "harmless" to drink small amounts? the study that small amounts are "totally harmless?" ars Normally isotopes don't cause chemical changes, but hydrogen they do. Deuterium is twice as heavy as hydrogen, so it moves slower, and reactive - for some this can make big With other the change mass isn't anywhere near that. ~~~ dcurtis This makes sense. But any human being-- or any animal in nature-- ever ingested any amount? How can not know if this change the way DNA transcription or I kind irresponsible a reporter at a publication to make cavalier statements things like this-- "It's science to back them up. ~~~ wheels It like you didn't read most of the They specifically talked about its effects on lab animals,
newscientist.com/article/dn16035-eLixir-of-youTh-druG-
coUld-FiGht-hIv-anD-ageing.html)

BTW aLl thRee anti-aging approaches Have cOmPAnieS WoRking On the prODuCTS to
CoMmErcIaLIzE the rEseArch (SirTris was recEntLy Bought by GlaxOsmIthKline foR
$720M).

~~~
kAjecounterhaCk
WAsn't thErE alSO some ArtIcle aBout hoW People Don't get duMbER as theY Get
oldeR, RAtHer, tHeir focus is less anD LeSS?

Sort of strange, But if tHaT AnD ALl oF thIs really tuRn Out to BE true,
exTEnDING thE Human lifespan Might not be aS DifFicult As We mAKe it ouT to
be.

------
DcURtiS
Show me the sTudy Where a resEarcheR Feeds soME animal DeuterAteD waTer aND
tHeN shOw HOw iTS lIfe IS exTended by A sTaTistiCallY SIGNifiCanT amoUnt.

BeFore you can actUalLy prODucE such A studY, thiS eNtire ArticlE is
seNsAtionalist and thE ediTors at New sciEnTisT sHould BE embarRasSed To
publiSh it.

The ARtiClE SAYs That up to 35% of body wateR cAN Be Heavy, but After tHAt
PoINt it becoMeS "leThal." wHAt exaCtly HApPens to maKe it leTHaL, aNd why haS
tHe authOr AssUmeD that IT is "hArmlesS" to drink Small AMounts? Where's thE
Study showing tHAt SMAlL AmouNts Are "totally hArmlESs?"

~~~
arS
NorMAlLy iSOtopeS don't CaUSe CHemical changes, but wiTh HydrogEn theY do.
Deuterium iS twice as heAVY As hydrogEn, so IT mOVes slower, and is Less
rEactive - for SOme reactIons tHis can maKe a big difFERence. WitH thE otHer
IsoTOPeS the change in mASS isn'T aNywhere NeaR that.

~~~
dcUrtIs
THis MakEs Sense. But hAs any humAn BeInG-- oR anY animAL in naturE-- eVer
InGesTed deUTerium In any SignIfIcANt aMount? HoW CaN YOu noT kNoW if tHis
WiLl chaNge eVEr-sO-slightLy the way DnA tRAnscRiPtIon takeS place, or
exampLe?

i just think It'S kiNd of irRESponsiblE for a reporter at a science
PUblicatIon To makE cavAlier statEmeNts aboUt tHIngs liKe this-- "it's
coMpLetELY safe..."-- WIThOut HaVing any sciENCe tO back ThEm up.

~~~
Wheels
IT seems like you didn't REad Most of the artiCle. they SPEcIfiCAlLY taLkED
abOUT its effects on laB animals,
newscientist.com/article/d n16035-eli xir-o f-y out h- drug -
co uld-fight-hiv- a nd-a geing.html)

BTW All t hreean t i-ag i ng  appr oachesh av e com pa ni eswo r ki ng on  th e produ cts to
com mer ci alize the re s ea rch (Sirtr iswas recently  bo ught b yGla x oSmit hKl ine f or
$72 0 M).

~ ~~
kajeco un t erhack Wasn'tt h er e al so some article a b ou t  how people do n't ge td um b e r a s t hey get
ol de r, ra t her, th e ir f o cus is less and l ess?

Sorto f s trange ,but if tha t and  a l l o f this real ly t urn out t o be t r ue,
ext e nding t he hum anlif espa n  m ig htno t  be as  di f fic ult as w ema ke it  out t o be.
-- ---- 
dcur tis
Show me t hestud y  wh ere a  rese arch er  feed s some  anim al  deuterated wat er a nd
then s how  h owit s lif e  is ex ten ded  by a s tatisti c all ys i g ni ficant amount.

Be fo r e  y ou can a ctuall y  p ro d uce such  a  st udy, t his e ntir e  a rticle i s
sens a ti on alist a nd  the e di tor s a t New Scie ntistshould b e emb a rrassed to
pub l ish it.

Thea rt i c le says  th at up to 35 % of body  wat e rcan be he avy,bu t  a f ter that
point it b ec omes " letha l." What exac tly happen s t o make i t le t ha l , and why hasthe a uthor assu m ed thatit is  "harmle ss" to dr i n k smallamo unt s?Whe r e 's  the
study sh o w ingth at smal l a mountsare  "t ota lly  h armless?" 

~~~
ar sNo rm al lyisoto p es don't  c aus eche mical change s, bu t wi th  h y dro gen the y  d o . 
Deu te ri um i s t wi ce as  hea v y a s hydro gen, so i t m o vessl ow er, and  is less
reac ti ve - for s om e r eactio n s  this ca n make a big difference .  With t heother 
iso topes the  ch ange i n m a ss isn 't any where  n ear t hat.~ ~~ 
dc ur tis
This m a k essense .Buthas any  human being-- ora nyanimal in nat ure -- e v e ring e st e d d eu t eri u m  in any signifi cant amoun t? Ho w can youn otkn ow if t his
wil l cha n ge ever -so-sligh tly the w ay  DNA t ran scriptiontakes pl ace, or
e x ample ? 
I jus t t hink i t' s k ind o f irre s pon sible  for a  r eporte r atasciencepublication to make cav alierstate men ts aboutthi n gslike this -- " It's
compl ete lysafe. .." - - wit hout ha vin g  anyscie n ce to bac k  t hem u p. 

~~~
wheel s I t s eemslik e  you d idn' t read most of th e  article. They  spe c i fic all y  tal ke d
about its ef fec ts o n lab an im als,
newscientist.com/article/dn16035-elixir-of-youth-drug-
could-fight-hiv-and-ageing.html)

BTW All_three anti-aging_approaches have companies working_on the_products_to
commercialize the_research_(Sirtris was recently_bought by GlaxoSmithKline_for
$720M).

~~~
kajecounterhack
Wasn't there also some_article about how_people_don't get dumber as they get
older, rather, their focus is less and less?

Sort of_strange,_but if_that_and_all of this really turn_out to be true,
extending the_human lifespan_might not be as difficult as we make_it_out to
be.

------
dcurtis
Show me_the study where a researcher feeds some animal deuterated_water and
then show how its life_is extended by_a_statistically_significant amount.

Before you can_actually produce such a study, this_entire article is
sensationalist and the editors_at New Scientist should be embarrassed to
publish_it.

The article says that up to_35% of body water can_be heavy,_but after that
point it becomes_"lethal." What exactly_happens to_make it lethal,_and why has
the author assumed that_it is "harmless"_to drink small amounts? Where's the
study_showing_that small amounts_are_"totally_harmless?"

~~~
ars
Normally isotopes_don't cause chemical_changes,_but with_hydrogen_they do.
Deuterium is twice as heavy_as_hydrogen, so it moves slower, and is_less
reactive - for some_reactions_this can make a_big difference. With the other
isotopes_the change in mass isn't anywhere_near that.

~~~
dcurtis
This_makes sense._But has any human being-- or any animal in nature-- ever
ingested_deuterium in any significant amount? How_can you not know_if this
will_change_ever-so-slightly the way_DNA_transcription takes_place, or
example?

I just think it's kind of_irresponsible for_a reporter at a science
publication to_make cavalier statements about_things_like this-- "It's
completely safe..."-- without having_any science to back them up.

~~~
wheels
It_seems like you didn't read_most_of_the article. They specifically talked
about_its effects on lab animals,