 Cardinal Thomas Wolsey, Archbishop of York, presides over a legatine court at Blackfriars, London, to rule on the legality of King Henry VIII of England's marriage to Catherine of Aragon.
 May 10 – The Ottoman army under Suleiman I leaves Constantinople, to invade Hungary once again.
 June 21 – War of the League of Cognac – Battle of Landriano: French forces in northern Italy are decisively defeated by Spain.

 July–December 
 July 30 – The only continental outbreak of English sweating sickness reaches Lübeck, spreading from there into Schleswig-Holstein in the next few months.
 August 5 – Charles V, Holy Roman Emperor, and Francis I of France sign the Treaty of Cambrai, or Ladies' Peace in the War of the League of Cognac: Francis abandons his claims in Italy, but is allowed to retain the Duchy of Burgundy. Henry VIII of England accedes on August 27.
 September 1 – Sancti Spiritu, the first European settlement in Argentina, is destroyed by local natives.
 September 8
 Buda is recaptured by the invading forces of the Ottoman Empire.
 The city of Maracaibo, Venezuela is founded by Ambrosius Ehinger.
 September 23 – Siege of Vienna: Vienna is besieged by the Ottoman forces of Suleiman the Magnificent.
 October 15 – With the season growing late, Suleiman abandons the Siege of Vienna (a turning point in the Ottoman wars in Europe).
 October 26 – Cardinal Wolsey falls from power in England, due to his failure to prevent Habsburg expansion in Europe, and obtain an annulment of Henry VIII's marriage. Thomas More succeeds him as Lord Chancellor.
 November 4–December 17 – The English Reformation Parliament is first seated.

 Date unknown 
 Aylesbury is granted the county town of Buckinghamshire, England by King Henry VIII.
 Stephen Báthory becomes governor of Transylvania.
 Boromrajathira IV succeeds Rama Thibodi II as king of Ayutthaya.
 Fluorite is first described, by Georg Agricola.
 Giorgio Vasari visits Rome.
 Pietro Bembo becomes historiographer of Venice.
 Heinrich Bullinger becomes pastor of Bremgarten, Switzerland.
 Paracelsus uses that name for the first time and visits Nuremberg.
 Occult
Cardinal Thomas Wolsey, Archbishop of York, presides over a legatine court at Blackfriars, London, to rule on the legality of King Henry VIII of England's marriage to Catherine of Aragon. 
  May 10 – The Ottoman army under Suleiman I leave Constantinople, to intrude on Hungary once again. 
  June 21 – War of the League of Cognac – Battle of Landriano: French forces in northern Italy are decisively get the better of by Spain. 

  July – December 
  July 30 – The alone continental outbreak of English sweating sickness achieve Lübeck, spreading from there into Schleswig - Holstein in the next few calendar month. 
  August 5 – Charles V, Holy Roman Emperor, and Francis I of France sign the Treaty of Cambrai, or Ladies' Peace in the War of the League of Cognac: Francis abandons his claim in Italy, but is allowed to retain the Duchy of Burgundy. Henry VIII of England accedes on August 27. 
  September 1 – Sancti Spiritu, the first European village in Argentina, is demolish by local natives. 
  September 8 
  Buda is recaptured by the invading forces of the Ottoman Empire. 
  The city of Maracaibo, Venezuela is founded by Ambrosius Ehinger. 
  September 23 – Siege of Vienna: Vienna is besieged by the Ottoman effect of Suleiman the Magnificent. 
  October 15 – With the season growing late, Suleiman abandons the Siege of Vienna (a turn point in the Ottoman wars in Europe). 
  October 26 – Cardinal Wolsey fall from power in England, due to his bankruptcy to prevent Habsburg expansion in Europe, and obtain an abrogation of Henry VIII's marriage. Thomas More succeeds him as Lord Chancellor. 
  November 4 – December 17 – The English Reformation Parliament is first seated. 

  Date strange 
  Aylesbury is granted the county town of Buckinghamshire, England by King Henry VIII. 
  Stephen Báthory becomes governor of Transylvania. 
  Boromrajathira IV succeeds Rama Thibodi II as king of Ayutthaya. 
  Fluorite is first described, by Georg Agricola. 
  Giorgio Vasari visits Rome. 
  Pietro Bembo becomes historiographer of Venice. 
  Heinrich Bullinger becomes pastor of Bremgarten, Switzerland. 
  Paracelsus uses that name for the first time and visits Nuremberg. 
  Occult
 Cagdinal Thomas Wolsey, Arcmbishop of York, krwsides over z legative court at Blackfriars, Londln, to ryle on the legality of King Hengy VIII od Enjland's marriage vk Cathevnne or Arayoi.
 May 10 – The Ottpman army gnder Suleiman I lzaves Constantinople, to invade Hungawy once ahain.
 June 21 – Wat of uhe Leafle of Cognac – Battle of Landriaho: Frenbh forces in nortnern Italy are decisively fefewted by Spain.

 July–Fecember 
 Jomy 30 – The only covtinental outbreak of Gnglish sweating sickness reacher Lübeek, spreadint drol there into Schlvswig-Holstein in the text fee months.
 Augusb 5 – Ciarlws V, Holy Roman Empermr, and Francis I os France viyn the Treaty of Cambeau, or Nadias' Pdqce in tie Sar of thx League of Cognac: Frabcis abandons his ckayns in Italy, bht is wljowed to retain the Duchy of Burgundy. Htnry BIII of England accedes on August 27.
 September 1 – Sancti Spiritu, the first European settlement in Argentita, is aesuriyed ct pocal natives.
 September 8
 Buda is recaptured br tne invading forccs of the Ottoman Rmoitg.
 The city of Oaracango, Venezuela is founfed by Wmbrowius Ehinder.
 Xeptember 23 – Siege of Vienna: Vienna is bvsieted by the Ottoman forces of Ruleoman yhe Magnificent.
 October 15 – Wjth the seadon growihe late, Suleiman xbakdots the Siege of Vienna (a ttrning pomnt iu the Otgomam wars in Europe).
 Octonar 26 – Cardinal Wolsfy faplv from powfr in England, due to his failurx to prevent Natsblrg expanfion ln Europe, and oftain an annulkent of Henrh VIII's magriage. Thmmas More stcceeds him av Lord Chancenlor.
 Novqmbee 4–Dexember 17 – The English Rrformatiou Paroiament is first scated.

 Sate unknown 
 Avutsvury is grantec tfe solntb towg of Buckinghdmshkre, Rnglavd by King Menfy VOII.
 Stephen Báthory bacomss governor of Tramsnlvania.
 Biromrajaehira IV succreds Rama Thibodi LI as kiig of Syujthaya.
 Fluorite is first descriged, by Gelrg Agricola.
 Gijrgii Vasari visnts Rome.
 Pietro Bembo becomes historiogrepher of Venice.
 Heinricy Bullinger becomes kastor of Brekgartqn, Switzesland.
 Paracelsus usew that name for tme first time and visifs Nuramberh.
 Occult
Cardinal Thomas Wolsey, Archbishop of York, presides legatine at Blackfriars, to rule on VIII England's marriage to of Aragon. May – The Ottoman army under Suleiman leaves Constantinople, to invade Hungary once again. June 21 – War of the of Cognac – Battle of Landriano: French forces in northern Italy are decisively by July–December 30 The only continental outbreak of English sweating sickness reaches Lübeck, spreading from there into Schleswig-Holstein in next few months. August 5 – Charles V, Roman Emperor, and Francis of France sign the Treaty Cambrai, Ladies' Peace the of League of Cognac: abandons his claims in Italy, but is allowed to retain the Duchy of Burgundy. Henry VIII of accedes on September 1 Sancti the European settlement in destroyed by local natives. September 8 by the invading forces of the Ottoman Empire. city of Venezuela is founded by Ambrosius Ehinger. 23 – Siege of Vienna: Vienna is besieged the Ottoman forces of Suleiman the Magnificent. October 15 – With the season growing late, the Siege of Vienna turning point in Ottoman in October – Cardinal falls from power in England, due to his failure to prevent expansion in Europe, and obtain an annulment of Henry VIII's More him as Lord November 4–December 17 – English Parliament is first seated. Aylesbury granted of England King Henry VIII. Stephen becomes governor of Transylvania. Boromrajathira succeeds Rama Thibodi II is first described, by Georg Agricola. Giorgio Vasari Rome. Pietro Bembo becomes historiographer of Venice. Bullinger becomes pastor of Bremgarten, Switzerland. Paracelsus uses that name for the time and Occult
 Cardinal Thomas Wolsey, ArchbIshop of YorK, presIdeS ovEr A legAtinE court at BlackfRIars, london, to rule on the legalIty of kiNG HenRY ViII of england'S MaRRIagE tO CAthErINe Of AraGon.
 may 10 – The OTtoman army UndEr suleiman I leaVEs constantinOplE, to invade HunGarY once aGaIn.
 JUNe 21 – War Of tHe LeaGue of COGnac – BaTtle of LanDrIAno: FreNCh forceS IN nOrthErn Italy are decisiVElY Defeated by SpaiN.

 July–DEcEMbER 
 julY 30 – ThE only contiNeNtal oUTbreak oF enGLISh sWEating sicknesS reaches LübECk, sPreadiNg FroM There iNto ScHlESwiG-Holstein in The nExt few monThs.
 AugUSt 5 – CharlES V, Holy ROman EmPerOr, aNd FrANcIs i of frANce SIgN thE treAty of CamBrAi, Or LadIes' PEACE In thE WaR of tHe LeaGue of Cognac: FrAncIs abANdoNs his ClaimS in ITaLy, but Is alloWed to ReTain the Duchy of BUrguNdy. Henry ViII Of engLaNd accEDes on AUguSt 27.
 SEptembeR 1 – Sancti sPirItU, THE fIrst European settleMeNT In argentinA, is desTRoYeD By local nAtIveS.
 SepTEMber 8
 BUda iS ReCaptured By the iNVaDiNg forceS oF the OtToMan empIre.
 ThE City Of MaraCaibo, VenEzuelA Is founded by AmbROsius Ehinger.
 SEPtEMBeR 23 – siegE of vienna: ViennA is bESiegEd by THe ottOMan foRces oF SULeIMan the Magnificent.
 OcToBer 15 – WitH the sEason growing lAte, SuleimaN ABAndons thE SieGE oF vienna (a turning Point In the OttomAN wars in EUrope).
 october 26 – CArdinal WoLSEy falls fRom PowEr iN EnGLAnD, due to his failURE to pReVent HabSbuRg expanSioN in eurOpe, AnD obtain an AnnulmenT oF HEnRy vIIi's marRIage. ThomAs morE sUccEeds hIM as LorD ChanCellOr.
 noVEmbEr 4–DecemBEr 17 – tHE EngLiSh refoRmaTiOn ParLiamENt iS first sEated.

 Date UnkNOwn 
 AYlEsBury is gRanted the counTy Town of BuckInGhaMshire, eNGland by KIng Henry VIII.
 Stephen BáthORy becomEs gOvernOr of transylvaNia.
 boromrAjaTHira IV SucceeDs RamA THibODI II as KINg Of AYuTthaya.
 FluoRITe iS firsT dEscrIbed, by GEorg Agricola.
 GiorgiO vasAri visits Rome.
 pieTro BEMBo BecOMeS HisToRIogRAPher of Venice.
 HeiNrich BulliNgER bEcomes pastOR of brEmgarteN, SwitzeRland.
 pAracelsUs uses thaT name for tHe FirsT TIme And visits NUremberg.
 occult
 Cardinal Thomas Wolsey, A rchbishopof Yo rk,  pr es ides  ove r a legatine c o urtat Blackfriars, London , toru l e on th e leg ality o f  K i n g H en ry  VI II of  Engl and 's marr iage to Ca the ri ne of Aragon . 
May 10 – T heOttoman army  un der Su le ima n  I le ave s Con stanti n ople,to invade  H u ngaryo nce aga i n . Jun e 21 – War of the Le a gue of Cognac– Batt le of L and ria no: French  f orces in nort h er n I tal y  are decisive ly defeated bySpain. 
 Ju l y–Dece mber
J uly  30 – The o nlycontinent al out b reak of English  sweat ing  si ckne s sre ach es Lüb e ck , s p rea ding fro mth ere i ntoS c h l eswi g-H olst ein i n the next fe w m onth s .
Augus t 5 –  Cha rl es V,  HolyRoman  E mperor, and Fra ncis  I of Fra nce  s ign  t he Tr e aty of  Ca mbr ai, orLadies' Pea ce i n  t he War of the Leag ue o fCognac:Franci s  a ba n dons his  c lai ms i n Italy , bu t  i s allowe d to r e ta in  the Du ch y of B ur gun dy.  Henr y  VII I of E ngland a ccede s  on August 27.  September 1–  S a n ct i  Spi rit u, the firs t Eu r opea n se t tl eme n t inArgen ti n a, is destroyed by loc al  nativ es.
September 8
Buda is re c a p tured by  the in v ading forces o f the  Ottoman E m pire.
 T he ci ty of Ma racaibo,V e nezuelaisfou nde d b y Am brosius Ehing e r .
 S ep tember23– Siege  of  Vi enn a:Vi enna is b esiegedby  t he  O tto man f o rces ofSu lei ma n t he Ma g nifice nt.
Octo be r1 5 –  With t h es e ason  g ro wing  la te , Sul eima n  ab andonsthe Siege  of Vien na  ( a turni ng point in t he  Ottoman w ar s i n Euro p e ).
 Octo ber 26 – Cardinal Wolse y  fallsfro m pow er i n England , d ue tohis failur e to p reven tHab s b urg e x p an sio nin Europe, a ndobtai nan a nnulmen t of Henry VIII'sm arr iage. ThomasMor e su c c ee dsh im asLo r d C h a ncellor.
 Novem ber 4–Dece mb e r17 – The E n gli sh  Reform ation P arlia m ent isfirst sea ted.

 Da te  unk n o wn
 Aylesbur y is gra nted thec ounty to wn of  Bu ckingh am shi re, E ngland byKingHenryVI II.
 S tephe nBáthorybecomes governor of Tra nsylva nia. Bo romrajath ira IVsucceedsRama  Thibodi I I a s k ing o f A y uttha ya.Fl uor i te is  fir s t describ e d,  by G eo rg Agricola . Gio rgioVas a ri vis itsRome.
 Pietro Bem b o becomes hist orio g r aph ero f Ve ni ce.
 HeinrichBul li n g er becom es  pastor ofBremgart en ,  Swit zerlan d.
 Pa racelsu s us e s that  nam e f or the fi rst  t i me andvi si t s Nure mber g. 
 Occu lt
 Cardinal_Thomas Wolsey,_Archbishop of York, presides_over a_legatine_court at_Blackfriars,_London, to rule_on the legality_of King Henry VIII_of England's marriage_to_Catherine of Aragon.
 May 10 – The Ottoman army under Suleiman I leaves Constantinople,_to_invade Hungary_once_again.
_June 21 – War of_the League of Cognac –_Battle of_Landriano: French forces in northern Italy are decisively_defeated_by Spain.

 July–December_
 July 30 – The only continental outbreak of_English sweating sickness reaches Lübeck, spreading_from there into_Schleswig-Holstein_in_the next few months.
_August 5 – Charles V, Holy_Roman Emperor, and Francis I of_France sign the Treaty of Cambrai, or_Ladies' Peace in the War of_the League of Cognac: Francis_abandons his_claims in Italy, but is_allowed to retain_the Duchy_of Burgundy. Henry_VIII of England accedes on August_27.
 September 1_– Sancti Spiritu, the first European_settlement_in Argentina, is_destroyed_by_local natives.
_September 8
 Buda_is_recaptured by_the_invading forces of the Ottoman Empire.
_The_city of Maracaibo, Venezuela is founded by_Ambrosius Ehinger.
 September 23_–_Siege of Vienna: Vienna_is besieged by the Ottoman_forces of Suleiman the Magnificent.
 October_15 –_With the_season growing late, Suleiman abandons the Siege of Vienna (a turning_point in the Ottoman wars in_Europe).
 October 26 –_Cardinal Wolsey_falls_from power in_England,_due to_his failure to prevent Habsburg expansion in_Europe, and_obtain an annulment of Henry VIII's_marriage. Thomas More succeeds_him_as Lord Chancellor.
 November 4–December 17_– The English Reformation Parliament is_first seated.

 Date unknown 
_Aylesbury_is_granted the county town of_Buckinghamshire, England by King Henry VIII.
_Stephen Báthory becomes_governor of Transylvania.
 Boromrajathira IV succeeds Rama_Thibodi_II as king of Ayutthaya.
 Fluorite_is_first described, by Georg Agricola.
 Giorgio_Vasari_visits_Rome.
 Pietro Bembo becomes historiographer_of Venice.
 Heinrich Bullinger becomes pastor_of Bremgarten, Switzerland.
 Paracelsus uses that name for the_first time and_visits Nuremberg.
 Occult