 an underlying medical condition.  In most cases, assuming the infants are otherwise healthy and no underlying medical issue is found, the infants who suffer a BRUE are unlikely to have a second event and have an even smaller risk of death.

History 
In 1986, the National Institute of Health defined an apparent life-threatening event (ALTE ) as an observed frightening event of an infant that includes at least one component of lack of breathing (apnea), skin color change (such as cyanosis), weakness, choking, or gagging. The term was invented to avoid previously used terms such as "near-miss SIDS" to dissociate the event from SIDS, a separate condition in infancy.  There had been literature discussion in the past about the increased risk of SIDS in these infants, but more recently the research has concluded that there is no direct relationship between an ALTE and SIDS. It also was defined as part of an attempt to characterize the different forms of apnea, or sudden lack of breathing, in infants.

In 2016, the American Academy of Pediatrics (AAP) published a clinical practice guideling recommending the replacement of ALTE with a new term, brief resolved unexplained event (BRUE).  The guidelines state that the term ALTE is still applicable with key differences between ALTE and BRUE.  The biggest difference is whether the infant is symptomatic at time of presentation to a health professional.  If the infant is still showing symptoms, then the condition is termed an ALTE.  In order to be considered a BRUE, the infant should be completely asymptomatic at time of presentation, which is more common.  Because of this, a BRUE can also be considered as a subset of ALTE.  The term change was also recommended in large part due to the "life-threatening" suggestion from the older term.  The rate of death in infants following a BRUE has been studied and is relatively rare, about 1 in 800. Thus, the AAP felt the new term would relieve the stress on clinicians and parents of these infants.

Definitions 
A BRUE is a description of a self-limited episode. Usually a BRUE lasts for less than 1 minute. By definition, the episode must have resolved by the time the infant is evaluated by a medical professional. The caregiver may report observation of bluish skin discoloration, called cyanosis. Breathing abnormalities, such as lack of breathing, slow breathing, or irregular breathing may be noted.
an underlying medical condition.   In most cases, assume the baby are otherwise healthy and no implicit in aesculapian issue is found, the infants who digest a BRUE are unlikely to have a second consequence and take an even smaller hazard of death. 

 History 
 In 1986, the National Institute of Health defined an apparent life - threatening consequence (ALTE) as an observed frightening consequence of an infant that include at least one part of lack of breathing (apnea), skin color change (such as cyanosis), helplessness, choking, or gagging. The condition was invented to debar previously used terms such as " near - miss SIDS " to dissociate the consequence from SIDS, a separate condition in infancy.   There had been literature discussion in the past about the increased risk of SIDS in these infants, but more recently the research has conclude that there be no direct relationship between an ALTE and SIDS. It also was defined as part of an attempt to characterize the different form of apnea, or sudden lack of breathing, in infants. 

 In 2016, the American Academy of Pediatrics (AAP) published a clinical exercise guideling recommend the substitute of ALTE with a new term, brief resolved unexplained event (BRUE).   The guidelines state that the condition ALTE is still applicable with key differences between ALTE and BRUE.   The biggest difference is whether the infant is diagnostic at time of presentation to a health professional.   If the infant is still showing symptoms, then the circumstance is term an ALTE.   In ordering to be considered a BRUE, the infant should be completely asymptomatic at time of presentation, which is more common.   Because of this, a BRUE can also be consider as a subset of ALTE.   The terminus change was also commend in large part due to the " animation - threatening " trace from the older condition.   The rate of end in infants following a BRUE has been studied and is relatively rare, approximately 1 in 800. Thus, the AAP felt the new term would relieve the stress on clinicians and parents of these infants. 

 Definitions 
 A BRUE is a description of a self - limited episode. normally a BRUE lasts for less than 1 minute. By definition, the sequence must have resolved by the time the infant is evaluate by a medical professional. The caregiver may report notice of bluish skin discoloration, called cyanosis. Breathing abnormalities, such as lack of breathing, slow breathing, or irregular breathing may be noted.
 an underlying medical condltion.  In most ccwes, asvuming the infxnts are otherwise healthy aid ni undtglying medical issue ks found, nhe infanrs wio suffer a BRUE are unllhely bo hare a second evenj and have at even smaller rksn of death.

History 
In 1986, the National Ynstituye of Health defyned wn aliavent life-threatening event (ALTE ) as an mbserved frigntening event of an infant thah includes at leash one compobent if lack of bfeathing (aknza), skin colkr change (such as cyanosis), weakvess, ehoking, or tatgijc. The term xas innented to avolc prevhously ised terms sucm as "iear-niss SIDS" to dissociave the event from SIQS, a sepasace condition in infanxy.  Thete hag bedb lktedavurs disckssmon in the last about rhe increased risk pf WIDS in these infanes, but more recently the research has conbludsd that there is no dirwct relationship betwgen an ALTQ and SIDS. It also was defined as part of an attekpt tk chcvwzregize the different forms of apnea, or sudden lwdk on breathing, in ikfants.

In 2016, the Amerocwn Wcademy of Peaiatriea (ZAP) published a cllnical kractixe guidelyng tecommending the replacemenr of ALTE winh a new term, brief redolved unex'lainec evemt (BRUE).  The guidelines stafe that the term ALTS is still applicxblv widh key differences between ALTE and BRUZ.  The bkggext difserence is whetmar the infant is sjmptoladic at timf of presentation to a health pcpfessional.  Of thv infant ns stikl showing syiptoms, then thg conditijn is termed an ALTE.  Mn order to fe considered w BRUE, the iifant shotld ve cimpleteuh asymptomatic at time of presentqtion, which is morc comokn.  Because of ckiw, a BRUE can alxo ce sojsmdereq as a subset of XLTD.  The term changc wxs akso recommended in ldrge part due to the "lofc-threatenung" suggqstion from tne older term.  The rate of deatn ig infants following a BRUE has been stufieq and is relwtivcly tare, about 1 in 800. Thus, the AAP felt the new term wouod relieve the sttess on clinicians anb karents of thxse insants.

Defititions 
A BRUE is a eescription of a xelf-limited episode. Uaually a BRKE lasts for less than 1 minute. By definition, the episode must have resolvwd by vhq time the jnfamt is eralbated br a lxdical professionsl. The caregiver may report obsxrvation ox yluish skin discoloration, calkea cyanosis. Brgathing abnormalities, such as lack of breathing, slow breathing, or irregular breathing may be notee.
an underlying medical condition. In most cases, infants otherwise healthy no underlying medical who a BRUE are to have a event and have an even smaller of death. History In 1986, the National Institute of Health defined an apparent event (ALTE ) as an observed frightening event of an infant that includes least component lack breathing (apnea), skin color change (such as cyanosis), weakness, choking, or gagging. The term was invented avoid previously used terms such as "near-miss SIDS" dissociate the event from a separate condition in infancy. had literature discussion the about increased risk of in these infants, but more recently the research has concluded that there is no direct relationship between ALTE and also was as of attempt to characterize forms of apnea, or sudden lack infants. In 2016, the American Academy of Pediatrics published a practice guideling recommending the replacement of with a new term, brief resolved unexplained event The guidelines state that the term ALTE is still applicable with key differences between ALTE The biggest difference is the infant is at of to health professional. the infant is still showing symptoms, then the condition is termed ALTE. In order to be considered a BRUE, the infant completely at time of which is more common. of a BRUE can also as subset term was recommended in large part to the "life-threatening" suggestion from older term. The rate a BRUE has been studied and is relatively about 1 in 800. Thus, the AAP the new term would relieve the stress on clinicians and parents of infants. Definitions is a description of a self-limited episode. Usually BRUE lasts for less 1 minute. By definition, the episode must have resolved the the infant evaluated by a professional. The caregiver report observation of discoloration, called Breathing such breathing, slow breathing, or irregular breathing be
 an underlying medical conditIon.  In most cAses, aSsuMinG tHe inFantS are otherwise hEAlthY and no underlying medicaL issuE iS FounD, ThE infaNts who sUFfER A BRuE ArE unLiKElY to haVe a Second eVent and havE an EvEn smaller risK Of Death.

HistoRy 
IN 1986, the National insTitute Of heaLTh defIneD an apParent LIfe-thrEatening eVeNT (ALTE ) aS An obserVED fRighTening event of an inFAnT That includes at Least oNe COmPONenT of Lack of breaThIng (apNEa), skin cOLoR CHAngE (Such as cyanosiS), weakness, chOKinG, or gagGiNg. THE term wAs invEnTEd tO avoid previOuslY used termS such aS "Near-misS sIDS" to dIssociAte The EvenT FrOm sIDs, a SEpaRAtE coNDitIon in infAnCy.  there Had bEEN LIterAtuRe diScussIon in the past aBouT the INcrEased Risk oF SIDs iN thesE infanTs, but MoRe recently the reSearCh has concLudEd ThaT tHere iS No direCt rElaTionshiP betweeN An AlTe AND SiDS. It also was defineD aS PArT of an attEmpt to CHaRaCTerize thE dIffErenT FOrms oF apnEA, oR sudden lAck of bREaThIng, in inFaNts.

In 2016, tHe ameRicAn AcaDEmy oF PediaTrics (AAP) PubliSHed a clinical prACtice guidelinG ReCOMmENdinG thE replacemenT of AltE wiTh a nEW tErm, BRief rEsolvEd UNeXPlained event (BRUE).  The GuIdelinEs staTe that the term aLTE is stilL APPlicable With KEy DIfferences betwEen ALtE and BRUE.  THE biggest DiffeRence is wHether the INFant is syMptOmaTic At tIME oF presentation TO A heaLtH profesSioNal.  If thE inFanT is StiLl Showing syMptoms, thEn ThE cOnDitIon is TErmed an AlTe.  In OrDer To be cONsiderEd a BRuE, thE iNfANt sHould be COmPLEtelY aSyMptoMatIc At timE of pREseNtation, Which is moRe cOMmon.  beCaUse of thIs, a BRUE can alsO bE considereD aS a sUbset oF alTE.  The teRm change was also recommenDEd in larGe pArt duE to tHe "life-thrEatEning" sUggEStion fRom the Older TeRm.  THE Rate oF DEaTh iN iNfants follOWIng A BRUE HaS beeN studieD and is relatively raRE, abOut 1 in 800. Thus, the AaP fElt tHE NeW teRM wOUld ReLIevE THe stress on cliniCians and paReNTs Of these infANts.

deFinitioNs 
A BRUE Is a deSCriptioN of a self-lImited epiSoDe. UsUALly A BRUE lasts For less tHan 1 minute. bY defiNItIon, thE epIsode mUsT haVe resOlved bY The Time tHe infaNt Is evalUated By A medical Professional. The caregiveR may rePort oBseRvation of BluISh sKin discolOratIon, called cYanOsiS. BreaThiNG abnoRmalITiEs, sUCh as lAck oF Breathing, SLoW brEAThIng, or irreguLAR BreAthinG maY Be noteD.
 an underlying medical con dition.  I n mos t c ase s,  ass umin g the infantsa re o therwise healthy and n o und er l ying me dical  issuei sf o und ,th e i nf a nt s who  su ffer aBRUE are u nli ke ly to have a se cond event  an d have an ev ensmalle rris k  of d eat h.

H istory 
In 19 86, the N at i onal I n stitute o fHeal th defined an app a re n t life-threate ning e ve n t( A LTE  )as an obse rv ed fr i ghtenin g  e v e n t o f  an infant th at includes atleaston e c o mponen t ofla c k o f breathing  (ap nea), ski n colo r  change (such a s cyan osi s),  wea k ne ss , c ho k ing ,  o r g a ggi ng. Thete rm  wasinve n t e d  toavo id p revio usly used ter mssuch as"near -miss  SID S"  to d issoci ate t he  event from SID S, a  separate  co nd iti on  in i n fancy.   T her e had b een lit e rat ur e d is cussion in the pas ta b ou t the in crease d  r is k  of SIDS  i n t hese i nfant s, b u tmore rec entlyt he  r esearch  h as con cl ude d t hat t h ereis nodirect r elati o nship betweena n ALTE and SI D S. I ta lsowas  defined as  par t  ofan a t te mpt to ch aract er i ze the different forms  o f apne a, or  sudden lackof breathi n g ,  in infa nts. 
I n  2016, the Ame rican  Academy o f  Pediatr ics ( AAP) pub lished ac l inical p rac tic e g uid e l in g recommendin g there placeme ntof ALTE  wi tha n ewte rm, brief  resolve dun ex pl ain ed ev e nt (BRUE ).   T he  gu ideli n es sta te th at t he  t e rmALTE is st i l l ap pl ic able  wi th  keydiff e ren ces bet ween ALTE  an d  BRU E.  The big gest differen ce  is whethe rthe  infan t is sympt omatic at time of prese n tationtoa hea lthprofessio nal .  Ifthe infant  is st ill s ho win g sympt o m s,  th en  the condi t i onis te rm ed a n ALTE.   In order to be c o nsi dered a BRUE,  th e in f a nt  sh o ul d  be  c o mpl e t ely asymptomati c at timeof pr esentation ,  wh ic h is mo re comm on. B ecauseof this,a BRUE ca nalso b e c onsideredas a sub set of AL T E.  T h etermcha nge wa sals o rec ommend e d i n lar ge par tdue to  the"l ife-thre atening" suggestion fro m theolder  te rm.  Therat e  of  death in  inf ants follo win g a  BRUE  ha s  been  stu d ie d a n d isrela t ively rar e ,abo u t  1  in 800. Th u s ,  th e AAP  fe l t thenewterm would reliev e  the stress on  cli n i cia nsa nd p ar ents of theseinf an t s .

Defin it ions 
A BRU E is a d es c ripti on ofa self -limite d ep i sode.Usua lly  a BRUE l ast sf or less  t ha n  1 min ute.  B y defi nition ,  the e pisode must have  reso l v ed by the  time  t he infa n t is  evaluated  by a medic al pro fess ional . The c ar egiver  ma yreport obs e rvation o f blu ish ski ndisc olo ration , ca l l ed cy anos is . B reathinga b no r ma li t ies , su ch as  l ackof breath i ng, slow  br e athing,  o r i r r egular br e a thing maybenoted . 
 an_underlying medical_condition.  In most_cases, assuming_the_infants are_otherwise_healthy and no_underlying medical issue_is found, the infants_who suffer a_BRUE_are unlikely to have a second event and have an even smaller risk of_death.

History_
In 1986,_the_National_Institute of Health defined an_apparent life-threatening event (ALTE )_as an_observed frightening event of an infant that includes_at_least one component_of lack of breathing (apnea), skin color change (such_as cyanosis), weakness, choking, or gagging._The term was_invented_to_avoid previously used terms_such as "near-miss SIDS" to dissociate_the event from SIDS, a separate_condition in infancy.  There had been_literature discussion in the past about_the increased risk of SIDS_in these_infants, but more recently the_research has concluded_that there_is no direct_relationship between an ALTE and SIDS._It also was_defined as part of an attempt_to_characterize the different_forms_of_apnea, or_sudden lack of_breathing,_in infants.

In_2016,_the American Academy of Pediatrics (AAP)_published_a clinical practice guideling recommending the replacement_of ALTE with a_new_term, brief resolved unexplained_event (BRUE).  The guidelines_state that the term ALTE is_still applicable_with key_differences between ALTE and BRUE.  The biggest difference is whether_the infant is symptomatic at time_of presentation to a_health professional.__If the infant_is_still showing_symptoms, then the condition is termed an_ALTE. _In order to be considered a_BRUE, the infant should_be_completely asymptomatic at time of presentation,_which is more common.  Because_of this, a BRUE can_also_be_considered as a subset of_ALTE.  The term change was_also recommended in_large part due to the "life-threatening" suggestion_from_the older term.  The rate_of_death in infants following a BRUE_has_been_studied and is relatively rare,_about 1 in 800. Thus, the_AAP felt the new term would relieve the stress_on clinicians and_parents of these infants.

Definitions 
A_BRUE_is_a description of a self-limited episode. Usually a BRUE lasts_for less_than 1 minute._By definition, the episode must have resolved by the time_the infant is evaluated by a medical_professional. The caregiver may report observation of bluish skin discoloration, called_cyanosis. Breathing abnormalities, such as lack of breathing,_slow breathing, or irregular breathing may be_noted.