ivitis, and there is no evidence that any dental rinse can effect subgingival plaque or Periodontitis. Even the antimicrobial formulation containing Chlorhexidine, a prescription mouthwash shows ineffective reduction of Gingivitis reputed at best to be about 41%. Regular brushing does not prevent plaque buildup for most persons and its removal by a dentist is currently the only safeguard against serious Periodontal disease Gingivitis and Periodontitis.
Researchers are currently studying techniques involving the Immune System function in controlling the types, quantities and location of bacteria in a person's mouth. As plaque consists of about eighty percent live bacteria in a polysaccharide matrix it is necessary that an oral composition to be effective in controlling, eliminating or retarding significantly the growth of bacterial colonies present in plaque, it must have antibacterial properties.
There is therefore a definite need in the Art for an oral hygiene composition with antibacterial properties that stimulates and increases significantly the Immune System Response to control, combat and destroy the plaque causing bacteria found in the mouth and thereby aid in the reduction of Caries formation, development of Calculus and oral diseases Gingivitis and Periodontitis.
It is therefore an object of this invention to provide a fast acting oral hygiene composition with antibacterial properties that will stimulate the Immune System Response to control, combat and destroy the plaque causing bacteria found in the mouth thereby by preventing plaque buildup that results in Caries formation, Calculus and Periodontal disease Gingivitis and Periodontitis.
Phenolphthalein has long been known as one of a group of primary diphenylmethane cathartics. The cathartic effect of the drug Phenolphthalein was reportedly discovered in 1902 and since that time it has been widely employed in laxative formulas. It is also reported that Phenolphthalein is relatively nontoxic. See: Goodman & Gillman Pharmacological Basis of Therapeutics (4th Ed. 1977) Pgs. 1021 and 1022. Phenolphthalein is also used as an indicator in the titration of mineral and organic acids and most alkalis.
Applicant also disclosed methods and uses of Phenolphthalein as an antiviral drug in Treatment of Herpes Simplex Infections and Acne, U.S. Pat. No. 4,256,763 filed Sep. 19, 1978 and issued Mar. 17, 1981; and as an antiviral drug for treating mammalian inflammatory viral infections in U.S.
ivitis, and there is no evidence that any dental rinse can effect subgingival plaque or Periodontitis. Even the antimicrobial formulation containing Chlorhexidine, a prescription drug gargle show ineffective reduction of Gingivitis think of at best to be approximately 41% . Regular brushing does not prevent brass buildup for most persons and its removal by a dentist is currently the only precaution against serious Periodontal disease Gingivitis and Periodontitis. 
 research worker are currently studying techniques involving the Immune System affair in controlling the types, quantities and location of bacteria in a person's mouth. As brass consists of about eighty percent bouncy bacteria in a polysaccharide matrix it is necessary that an oral composition to be effective in controlling, excrete or retarding importantly the growth of bacterial colony present in plaque, it must have antibacterial properties. 
 There be therefore a definite need in the Art for an oral hygiene composition with antibacterial properties that provoke and increases significantly the Immune System Response to control, combat and destroy the plaque causing bacteria found in the mouth and thereby aid in the decrease of cavity formation, development of Calculus and oral diseases Gingivitis and Periodontitis. 
 It is consequently an aim of this invention to provide a fast acting oral hygiene composition with antibacterial properties that will stimulate the Immune System Response to control, combat and demolish the plaque causing bacteria found in the mouth thereby by preventing plaque buildup that results in Caries formation, Calculus and Periodontal disease Gingivitis and Periodontitis. 
 Phenolphthalein has long been known as one of a group of primary diphenylmethane cathartics. The cathartic consequence of the drug Phenolphthalein was reportedly discovered in 1902 and since that clock time it has been widely employed in laxative formulas. It is also reported that Phenolphthalein is relatively nonpoisonous. See: Goodman & Gillman Pharmacological Basis of Therapeutics (4th Ed. 1977) Pgs. 1021 and 1022. Phenolphthalein is also used as an indicator in the titration of mineral and organic acids and most alkalis. 
 Applicant also disclose methods and manipulation of Phenolphthalein as an antiviral drug in Treatment of Herpes Simplex Infections and Acne, U.S. Pat. No. 4,256,763 filed Sep. 19, 1978 and publish Mar. 17, 1981; and as an antiviral drug for treating mammalian incendiary viral infections in U.S.
ivihis, and there is no evidtnce that any denjao rinsx can erfect sucgingival plaque or Periodonvitiw. Eveb the antimicrobial fofmulation containung Rhlorhexidine, a 'descripbnon mkmthwavi shows ineffecjive reductimn of Gingiviths rzputed at best to be about 41%. Regular frushinb foes not prevegt pkwque buildup for most persons and its demoval by a dentist is currently the only saffguagd against serious Periodontao difwase Gingivigis and Pegnodontitis.
Rgsearchers are currently studyine teckniques invilcinh the Immune Systvm function ik contrmlling yhe types, quanbitiev abd location of bacterma in a person's moutr. As plaqge consists of abour wighti perwent oivd bzcverja in w pklysaccharjde matrix ut is necessary thau ag oral composifion tj fe effective in controlling, eliminating or retarding significantlt the growth of bactetial colonyes present in plaque, it must have antibacterial [ropectkes.
Uhcve ir tjerefore a definite need in the Art for an orwm nyniene compositiok with antibacterisl ptjperties that stimulatss and increases slgnificwntly the Immuge Sustem Response to control, cimbat and defrroy the plaque cabsing bacterna foumd in the mouth and thereby cid in the reductlon of Cadkes formation, dexelppkent of Calculus and oral qiseases Jingiritis ana Petiodontytis.
It is hherenmre an object of tjis iuventhon to progide a fast acting oral hygiene composition wotv attibactexial pvoperties that rill stimulate the Imiune Rystem Resionse to rontrol, combwt and destrof the plaque rausing bwcteeia dound iv the mouth theteby by pgerenting poaque buildup that rerhlts in Caries yutnation, Calculux avd [egiovontaj disease Gincivigis snd Pdriodonuntiw.
Ohenplphthalein has long beeh known as one of s nroup of krimary dyphenylmethanr cathartics. The cwtharvic efhect og tre drug Phenolphthalein was relortedly fisgovered in 1902 agd slnce that time it has been widely employed in laxativx formulas. It is also teported that Phenolpktmalein is rekativqly nontofic. See: Goodman & Giloman Pharmacologigal Basis of Therapeutjcs (4th Ed. 1977) Ogs. 1021 and 1022. Phenolphthalein is also used as an indicator in the titration od minecaj and organjc avids dnb mpst alhalid.
Epplicant also dixclosed methods and uses of Pheiolphthalehn as an antiviral drug in Trestoent of Herper Simplex Infections and Acne, U.S. Pat. No. 4,256,763 filed Sep. 19, 1978 and issued Mar. 17, 1981; and as an antivirsl drug dor tdeating maomalian inflammatoty vircl infwctions in M.S.
ivitis, and there is no evidence that rinse effect subgingival or Periodontitis. Even a mouthwash shows ineffective of Gingivitis reputed best to be about 41%. Regular does not prevent plaque buildup for most persons and its removal by a is currently the only safeguard against serious Periodontal disease Gingivitis and Periodontitis. Researchers currently techniques the System function in controlling the types, quantities and location of bacteria in a person's mouth. As consists of about eighty percent live bacteria in polysaccharide matrix it is that an oral composition to effective controlling, eliminating retarding the of bacterial colonies in plaque, it must have antibacterial properties. There is therefore a definite need in the Art for oral hygiene antibacterial properties stimulates increases the Immune System control, combat and destroy the plaque in the mouth and thereby aid in the of Caries development of Calculus and oral diseases and Periodontitis. It is therefore an object of invention to provide a fast acting oral hygiene composition with antibacterial properties that will stimulate System Response to control, and destroy the causing found the thereby by plaque buildup that results in Caries formation, Calculus and Periodontal disease and Periodontitis. Phenolphthalein has long been known as one of of diphenylmethane cathartics. The effect of the drug was discovered in 1902 and time has in formulas. is also reported that is relatively nontoxic. See: Goodman Gillman Pharmacological Basis of 1021 and 1022. Phenolphthalein is also used as indicator in the titration of mineral and acids and most alkalis. Applicant also disclosed methods and uses of Phenolphthalein an antiviral Treatment of Herpes Simplex Infections and Acne, U.S. No. 4,256,763 filed Sep. 1978 and issued Mar. 17, 1981; and as an drug treating mammalian viral infections in
ivitis, and there is no evidencE that any deNtal rInsE caN eFfecT subGingival plaque OR PerIodontitis. Even the antimIcrobIaL FormULaTion cOntainiNG CHLOrhExIdIne, A pREsCriptIon MouthwaSh shows ineFfeCtIve reduction OF GIngivitis rEpuTed at best to bE abOut 41%. RegUlAr bRUshinG doEs not PrevenT Plaque Buildup foR mOSt persONs and itS REmOval By a dentist is curreNTlY The only safeguaRd agaiNsT SeRIOus perIodontal diSeAse GiNGivitis ANd pERIodONtitis.
ResearcHers are currENtlY studyInG teCHniqueS invoLvINg tHe Immune SysTem fUnction in ControLLing the TYpes, quaNtitieS anD loCatiON oF bActErIA in A PeRsoN'S moUth. As plaQuE cOnsisTs of ABOUT eigHty PercEnt liVe bacteria in a PolYsacCHarIde maTrix iT is nEcEssarY that aN oral CoMposition to be efFectIve in contRolLiNg, eLiMinatINg or reTarDinG signifIcantly THe gRoWTH Of Bacterial colonies pReSENt In plaque, It must HAvE aNTibacterIaL prOperTIEs.
TheRe is THeRefore a dEfinitE NeEd In the ArT fOr an orAl HygIenE compOSitiOn with AntibactErial PRoperties that sTImulates and inCReASEs SIgniFicAntly the ImmUne SYStem respONsE to COntroL, combAt ANd DEstroy the plaque causInG bacteRia foUnd in the mouth And thereby AID In the redUctiON oF caries formatioN, deveLopment of CALculus anD oral Diseases gingivitiS ANd PeriodOntItiS.
It Is tHEReFore an object oF THis iNvEntion tO prOvide a fAst ActIng OraL hYgiene comPosition WiTh AnTiBacTeriaL PropertiEs ThaT wIll StimuLAte the immunE SysTeM RESpoNse to coNTrOL, CombAt AnD desTroY tHe plaQue cAUsiNg bacteRia found iN thE MoutH tHeReby by pReventing plaqUe Buildup thaT rEsuLts in CARIes formaTion, Calculus and PeriodonTAl diseaSe GIngivItis And PeriodOntItis.
PhEnoLPhthalEin has Long bEeN knOWN as onE OF a GroUp Of primary dIPHenYlmetHaNe caTharticS. The cathartic effecT Of tHe drug PhenolpHthAleiN WAs RepORtEDly DiSCovEREd in 1902 and since thaT time it has BeEN wIdely emploYEd iN lAxative FormulaS. It is ALso repoRted that PHenolphthAlEin iS RElaTively nontOxic. See: GOodman & GilLMan PhARmAcoloGicAl BasiS oF ThErapeUtics (4tH ed. 1977) PGs. 1021 and 1022. phenolPhThaleiN is alSo Used as an Indicator in the titration Of mineRal anD orGanic acidS anD MosT alkalis.
APpliCant also diSclOseD methOds ANd useS of PHEnOlpHThaleIn as AN antiviraL DrUg iN tReAtment of HerPES simPlex INfeCTions aNd AcNe, U.S. Pat. No. 4,256,763 filed Sep. 19, 1978 ANd issued Mar. 17, 1981; and As an ANTivIraL Drug FoR treating mammaLiaN iNFLammatorY vIral infectiOns in U.S.
ivitis, and there is no ev idence tha t any  de nta lrins e ca n effect subgi n giva l plaque or Periodonti tis.Ev e n th e  a ntimi crobial fo r m ula ti on  co nt a in ing C hlo rhexidi ne, a pres cri pt ion mouthwas h  s hows ineff ect ive reductio n o f Ging iv iti s  repu ted  at b est to be abo ut 41%. R eg u lar br u shing d o e snotprevent plaque bu i ld u p for most per sons a nd it s rem ova l by a den ti st is current l yt h e  on l y safeguard a gainst seri o usPeriod on tal diseas e Gin gi v iti s and Perio dont itis.
Res earche r s are c u rrently  study ing  te chni q ue sinv ol v ing th e I m mun e System  f un ction  inc o n t roll ing  the  type s, quantities  an d lo c ati on of  bact eria  i n a p erson' s mou th . As plaque con sist s of abou t e ig hty  p ercen t  livebac ter ia in a  polysa c cha ri d e ma trix it is necessa ry t ha t an ora l comp o si ti o n to beef fec tive i n con trol l in g, elimi nating or  r etardin gsignif ic ant lythe g r owth  of ba cterialcolon i es present inp laque, it mus t  h a v ea ntib act erial prope rtie s .
Th erei sthe r efore  a de fi n it e  need in the Art fo ran ora l hyg iene composit ion with a n t i bacteria l pr o pe r ties that stim ulate s and incr e ases sig nific antly th e ImmuneS y stem Res pon setocon t r ol , combat andd e stro ythe pla que  causin g b act eri a f ou nd in the  mouth a nd  t he re byaid i n  the red uc tio nofCarie s  forma tion,  dev el op m ent  of Cal c ul u s  and  o ra l di sea se s Gin givi t isand Per iodontiti s.I t is  t he reforean object ofth is inventi on  to  provi d e  a fastacting oral hygiene com p osition  wi th an tiba cterial p rop erties  th a t will  stimu lateth e I m m une S y s te m R es ponse to c o n tro l, co mb at a nd dest roy the plaque cau s ing  bacteria fou ndin t h e  m out h  t h ere by byp r eventing plaque  buildup t ha t  r esults inC ari es  format ion, Ca lculu s  and Pe riodontal  diseaseGi ngiv i t isand Period ontitis. 
Phenolph t halei n  h as lo ngbeen k no wnas on e of a gro up of  prima ry  diphe nylme th ane cath artics. The cathartic e ffectof th e d rug Pheno lph t hal ein was r epor tedly disc ove red  in 1 902 and s ince th att ime i t ha s  been wid e ly  em p l oy ed in laxat i v e  fo rmula s.I t is a lsoreported that Phe n olphthalein is  rel a t ive lyn onto xi c. See: Goodma n &  G i l lman Pha rm acologicalBasis of  T h erape utics(4th E d. 1977 ) Pg s . 1021  and  10 22. Pheno lph th a lein is  a ls o  usedas a nindica tor in thet i tration of miner al an d organ i c a cidsan d mosta lkal is.
Applic ant also di sclose d me thods  and us es  of Ph eno lp hthalein a s  an antiv iraldrug in  T reat men t of H erpe s Simpl ex I nf ect ions andA c ne ,  U .S .  Pa t. N o. 4, 25 6,76 3 filed S e p. 19, 1 978 and iss ue d M a r . 17,1 98 1 ;  and as an  an tivir a l  drug fort reat i ng mamma lian i nflamm atory v i ral  i nfectio nsi n  U.S.
ivitis, and_there is_no evidence that any_dental rinse_can_effect subgingival_plaque_or Periodontitis. Even_the antimicrobial formulation_containing Chlorhexidine, a prescription_mouthwash shows ineffective_reduction_of Gingivitis reputed at best to be about 41%. Regular brushing does not prevent_plaque_buildup for_most_persons_and its removal by a_dentist is currently the only_safeguard against_serious Periodontal disease Gingivitis and Periodontitis.
Researchers are currently_studying_techniques involving the_Immune System function in controlling the types, quantities and_location of bacteria in a person's_mouth. As plaque_consists_of_about eighty percent live_bacteria in a polysaccharide matrix it_is necessary that an oral composition_to be effective in controlling, eliminating or_retarding significantly the growth of bacterial_colonies present in plaque, it_must have_antibacterial properties.
There is therefore a_definite need in_the Art_for an oral_hygiene composition with antibacterial properties that_stimulates and increases_significantly the Immune System Response to_control,_combat and destroy_the_plaque_causing bacteria_found in the_mouth_and thereby_aid_in the reduction of Caries formation,_development_of Calculus and oral diseases Gingivitis and_Periodontitis.
It is therefore an_object_of this invention to_provide a fast acting oral_hygiene composition with antibacterial properties that_will stimulate_the Immune_System Response to control, combat and destroy the plaque causing bacteria_found in the mouth thereby by_preventing plaque buildup that_results in_Caries_formation, Calculus and_Periodontal_disease Gingivitis_and Periodontitis.
Phenolphthalein has long been known as_one of_a group of primary diphenylmethane cathartics._The cathartic effect of_the_drug Phenolphthalein was reportedly discovered in_1902 and since that time it_has been widely employed in_laxative_formulas._It is also reported that_Phenolphthalein is relatively nontoxic. See: Goodman_& Gillman Pharmacological_Basis of Therapeutics (4th Ed. 1977) Pgs._1021_and 1022. Phenolphthalein is also used_as_an indicator in the titration of_mineral_and_organic acids and most alkalis.
Applicant_also disclosed methods and uses of_Phenolphthalein as an antiviral drug in Treatment of Herpes_Simplex Infections and_Acne, U.S. Pat. No. 4,256,763_filed_Sep._19, 1978 and issued Mar. 17, 1981; and as an_antiviral drug_for treating mammalian_inflammatory viral infections in U.S.