 and in accordance with the purposes of the present invention, as embodied and broadly described therein, the method of this invention comprises the formation of an autologous bioadhesive sealant comprising the steps of forming a platelet rich plasma or platelet poor plasma containing an anticoagulant. The platelet rich plasma or platelet poor plasma is then divided into two portions and the first portion is restored so that it can coagulate, thus forming a clot. The clot is triturated and the resulting serum is collected. The bioadhesive sealant composition is then prepared by combining a defined volume of the second portion of platelet rich plasma or platelet poor plasma with a sufficient volume of serum causing the fibrinogen in the second portion of platelet rich plasma or platelet poor plasma to be converted to fibrin, which then solidifies in the form of a gel. The use of electrical/electronic devices is growing rapidly in commercial blasting operations. For example, some detonators now rely on Integrated circuits to provide functionality. Providing electrical power to such devices is therefore necessary. This could be achieved in, for example wireless initiation devices, using a built-in battery or charged capacitor but providing the devices “live” presents significant safety concerns since the device may itself contain an explosive (detonators include a small charge of explosive) or be positioned within or in proximity to an explosive during use. Addressing these concerns by specifically designed safety systems, such as multiple layers of control at the level of circuit design, is possible. However, this adds to design complexity and operation and, in turn, this has implications with respect to cost, efficiency and application. Furthermore, safe operation is compromised if the safety system itself fails.
The possible problems of providing an explosive-containing initiation device with a built-in power supply can be overcome by supplying the device in multi-component form, with the power supply containing component being distinct from any component containing explosive material. However, in such cases, the use of a built-in power supply, such as a battery or other charge storage device, can limit the shelf life of that component due to unintended (bleeding of) electrical discharge. This may occur by a number of mechanisms, including chemical and physical mechanisms. An embodiment of this invention seeks to avoid the problem of shelf life limitation that may be associated with on-board power supplies such as batteries.
Further, in a blasting operation it is sometimes desirable to leave electrical devices in a borehole for a long time. In such cases the use of an on-board battery may limit the
and in accordance with the purposes of the present invention, as embodied and broadly described therein, the method acting of this invention constitute the formation of an autologous bioadhesive sealant comprising the footstep of form a platelet rich plasma or platelet poor plasma contain an anticoagulant. The platelet ample plasma or platelet poor plasma is then divide into two portions and the first share is restored so that it can coagulate, therefore forming a clot. The clot is triturated and the resulting serum is collected. The bioadhesive sealant composition is then prepared by combining a defined bulk of the second portion of platelet rich plasma or platelet poor plasma with a sufficient book of serum causing the fibrinogen in the second portion of platelet rich plasma or platelet poor plasma to be convert to fibrin, which then solidifies in the form of a gel. The use of electrical / electronic device is growing rapidly in commercial blasting operations. For example, some detonator nowadays rely on Integrated circuits to provide functionality. Providing electrical power to such devices is therefore necessary. This could be achieved in, for model wireless initiation devices, use a build - in battery or charged capacitor but provide the devices “ live ” presents significant condom concerns since the device may itself contain an explosive (detonators include a small charge of explosive) or be put within or in proximity to an explosive during use. Addressing these concerns by specifically designed condom systems, such as multiple layer of control at the level of circuit design, is possible. However, this total to design complexity and operation and, in turn, this has implications with respect to cost, efficiency and application. Furthermore, dependable operation is compromised if the safety system itself fails. 
 The potential problems of providing an explosive - containing initiation device with a build up - in power provision can be overcome by supplying the device in multi - component form, with the power supply incorporate component being clear-cut from any component containing explosive material. However, in such cases, the use of a construct - in power supply, such as a barrage or other charge storage device, can limit the shelf life of that component due to unintended (bleed of) electrical discharge. This may occur by a number of mechanisms, including chemical and physical mechanism. An shape of this invention seek to avoid the problem of shelf life limitation that may be associate with on - board power supplies such as battery. 
 Further, in a blasting operation it is sometimes desirable to leave electrical device in a borehole for a long time. In such cases the use of an on - board battery may restrict the
 anf in accordance with the purposes of thg presenv invenfion, as dmbodied and broadly describxd tyereib, the method of this ivvention bomprises the dormation of an aubjlogkms bimedhesive sealanj comprising the steps of xofmnng a platelet rich plasma or platelqt poor ppasma containigg am antjbocgulant. The platelet rich plasmz or pletelet poor plaxma is then divided into tao plrtions and the figst portion is wwstored so tfat it can coagulate, tgus forming a clot. The clot is grituxated and tye redolting serum is cjllected. The bioadhevive seslant compositlon iv tyen prepared by combiiing a defined volumg of the sacknd portion of plqtwlet tich [lasoq of pmavelst poog pmasma with a sufficiebt volume of serum vatwing the fibrjnogen ig the second portion of platelet rich pnasja or platelet poor plawma to be converted tl fibrin, rhich then solidifies in the form of a gel. The usa of xldctxlgal/euwchronic devices is growing rapidly in commerciwm nlssting operatijns. For exakppe, fome detonatots now xslg on Integrated cigcuits jo procide funcuionakity. Providing electrical piwer to such eevices is therefoxe necessary. Thix coukd be achieved in, for erample wireless ijitiation aevices, using a cuikt-hn battery or charged capasitor but proriding tfe dgvices “jive” presejts slcnificant safety clncerus sitce the degice may itself contain an explosive (detonatots hncnude a siall gharge of explofive) or be posntioned cithin or in proqimity to an exploside during use. Wddressing tiese concqrns by wpecifizxlly designed xafety systems, such as multiple layerx ow control at the lecel of circuit ceskgn, id 'ossifne. However, tvis xddr to ddsign complcxigy amd operation and, in durn, this has implicatooks with rgspect to cost, efficiemcy and applicatioj. Furvhermoce, safr okeration is compromised if the aafety sydtei itself faijs.
Thc pofsible proylems of providing an explosive-containinj initiation device wijh a built-in power sukpln can be oveccome fy supplyhng the device in muoti-component form, with the power supplg contdininh component being distinct from any component containing explosive materiql. Howxvqr, in such dasex, the ufz of a fuilv-ii power supply, subh as a battery or other charge rtorage gerice, can limit the shelf life ow that compongnt due to unintended (bleesing of) rlectrical discharge. This may ovcur by a number of mechsnisms, ibcludjng chvjiral and physical mecnanismv. An wmbodimwnt lf this invengiom deeks to wvoiv tke problem of shelf life limitatiin thar lay be associatev with on-boavd powet suppligs such as batterjes.
Fhgther, in a blastinb operation it is sometimes desiratlq to leave elexnrical devicex in a torehole for a long tima. In such cases the use of an on-board battery may lpmit the
and in accordance with the purposes of invention, embodied and described therein, the the of an autologous sealant comprising the of forming a platelet rich plasma platelet poor plasma containing an anticoagulant. The platelet rich plasma or platelet poor is then divided into two portions and the first portion is restored so it coagulate, forming clot. The clot is triturated and the resulting serum is collected. The bioadhesive sealant composition is prepared by combining a defined volume of the portion of platelet rich or platelet poor plasma with sufficient of serum the in second portion of rich plasma or platelet poor plasma to be converted to fibrin, which then solidifies in the form a gel. of electrical/electronic is rapidly commercial blasting operations. some detonators now rely on Integrated functionality. Providing electrical power to such devices is necessary. This be achieved in, for example wireless devices, using a built-in battery or charged capacitor providing the devices “live” presents significant safety concerns since the device may itself contain an include a small charge explosive) or be within in to explosive during Addressing these concerns by specifically designed safety systems, such as multiple of control at the level of circuit design, is possible. adds design complexity and and, in turn, this implications respect to cost, efficiency Furthermore, operation the system fails. The possible problems providing an explosive-containing initiation device a built-in power supply the device in multi-component form, with the power containing component being distinct from any component explosive material. However, in such cases, the use of a built-in power such as or other charge storage device, can limit the life of that component to unintended (bleeding of) electrical discharge. This may occur a of mechanisms, chemical and physical An embodiment of invention seeks to problem of life that with on-board power supplies such as Further, a blasting operation it is desirable electrical devices in a borehole for a long time. In such cases the use of battery may limit the
 and in accordance with the purPoses of the PreseNt iNveNtIon, aS embOdied and broadlY DescRibed therein, the method oF this InVEntiON cOmpriSes the fORmATIon Of An AutOlOGoUs bioAdhEsive seAlant comprIsiNg The steps of foRMiNg a plateleT riCh plasma or plAteLet pooR pLasMA contAinIng an AnticoAGulant. the platelEt RIch plaSMa or plaTELeT pooR plasma is then diviDEd INto two portions And the FiRSt PORtiOn iS restored sO tHat it CAn coaguLAtE, THUs fORming a clot. The Clot is trituRAteD and thE rEsuLTing seRum is CoLLecTed. The bioadHesiVe sealant ComposITion is tHEn prepaRed by cOmbIniNg a dEFiNeD voLuME of THe SecONd pOrtion of PlAtElet rIch pLASMA or pLatElet Poor pLasma with a sufFicIent VOluMe of sErum cAusiNg The fiBrinogEn in tHe Second portion of PlatElet rich pLasMa Or pLaTelet POor plaSma To bE converTed to fiBRin, WhICH ThEn solidifies in the fOrM OF a Gel. The usE of eleCTrIcAL/electroNiC deViceS IS growIng rAPiDly in comMerciaL BlAsTing opeRaTions. FOr ExaMplE, some DEtonAtors nOw rely on integRAted circuits to PRovide functioNAlITY. PROvidIng Electrical pOwer TO sucH devICeS is THerefOre neCeSSaRY. This could be achieveD iN, for exAmple Wireless initiAtion devicES, USing a buiLt-in BAtTEry or charged caPacitOr but proviDIng the deVices “Live” presEnts signiFICant safeTy cOncErnS siNCE tHe device may itSELf coNtAin an exPloSive (detOnaTorS inCluDe A small chaRge of expLoSiVe) Or Be pOsitiONed withiN oR in PrOxiMity tO An explOsive DuriNg UsE. addRessing THeSE ConcErNs By spEciFiCally DesiGNed Safety sYstems, sucH as MUltiPlE lAyers of Control at the lEvEl of circuiT dEsiGn, is poSSIble. HoweVer, this adds to design compLExity anD opEratiOn anD, in turn, thIs hAs implIcaTIons wiTh respEct to CoSt, eFFIcienCY AnD apPlIcation. FurTHErmOre, saFe OperAtion is Compromised if the saFEty System itself fAilS.
The POSsIblE PrOBleMs OF prOVIding an explosivE-containinG iNItIation deviCE wiTh A built-iN power sUpply CAn be oveRcome by suPplying thE dEvicE IN muLti-componeNt form, wiTh the poweR SupplY CoNtainIng ComponEnT beIng diStinct FRom Any coMponenT cOntainIng exPlOsive matErial. However, in such cases, The use Of a buIlt-In power suPplY, SucH as a batteRy or Other chargE stOraGe devIce, CAn limIt thE ShElf LIfe of That COmponent dUE tO unINTeNded (bleedinG OF) EleCtricAl dISchargE. ThiS may occur by a numbeR Of mechanisms, inCludING chEmiCAl anD pHysical mechaniSms. an EMBodiment Of This inventiOn seeks tO aVOid thE problEm of shElf life LIMiTAtion tHat mAy bE associatEd wItH On-board PoWeR SuppliEs suCh As battEries.
FURtheR, IN a blasting operatIon it IS SometIMes DesirAbLe to leaVE eleCtrical devIces in a boreHole foR a loNg timE. In such CaSes the Use Of An on-board bATtery may lImit tHe
 and in accordance with th e purposes  of t hepre se nt i nven tion, as embod i ed a nd broadly described t herei n, them et hod o f thisi nv e n tio nco mpr is e sthe f orm ation o f an autol ogo us  bioadhesive se alant comp ris ing the step s o f form in g a plate let  rich  plasm a  or pl atelet po or plasma contain i n gan a nticoagulant. The pl a telet rich pla sma or  p l at e l etpoo r plasma i sthend ividedi nt o t wop ortions and t he first po r tio n is r es tor e d so t hat i tc ancoagulate,thus  forminga clot .  The cl o t is tr iturat edand  the re su lti ng ser u misc oll ected. T he  b ioadh esiv e s e alan t c ompo sitio n is then pre par ed b y  co mbini ng adefi ne d vol ume of  these cond portion of  pla telet ric h p la sma  o r pla t elet p oor  pl asma wi th a su f fic ie n t vo lume of serum caus in g th e fibrin ogen i n  t he second p or tio n of p latel et r i ch  plasmaor pla t el et  poor p la sma to  b e c onv erted to f ibrin,  which t hen s o lidifies in th e  form of a ge l .T h eu se o f e lectrical/e lect r onic  dev i ce s i s  grow ing r ap i dl y  in commercial blas ti ng ope ratio ns. For examp le, some d e t o nators n ow r e ly on Integratedcircu its to pro v ide func tiona lity. Pr oviding e l e ctricalpow ertosuc h de vices is ther e f orene cessary . T his cou ldbeach iev ed  in, forexamplewi re le ss  in itiat i on devic es , u si nga bui l t-in b atter y or  c ha r ged  capaci t or b ut p ro vi ding  th edevic es “ l ive ” prese nts signi fic a nt s af et y conce rns since the  d evice mayit sel f cont a i n an exp losive (detonators incl u de a sm all  char ge o f explosi ve)  or be  po s itione d with in or  i n p r o ximit y to  an  e xplosive d u r ing  use.  A ddre ssing t hese concerns by s p eci fically desig ned  saf e t ysys t em s , s uc h  as m ultiple layersof control  a t  t he level o f  ci rc uit des ign, is  poss i ble. Ho wever, th is adds t odesi g n  co mplexity a nd opera tion and, in tu r n,  this  ha s impl ic ati ons w ith re s pec t tocost,ef ficien cy an dapplicat ion. Furthermore, safeoperat ion i s c ompromise d i f  th e safetysyst em itselffai ls. 
Thepos s ibleprob l em s o f  prov idin g  an explo s iv e-c o n ta ining initi a t i ondevic e w i th a b uilt -in power supplyc an be overcome  bys u ppl yin g  the  d evice in multi -co mp o n ent form ,with the po wer supp ly conta iningcompon ent bei n g  d i stinct  fro m a ny compon ent  c o ntainin gex p losive  mat er ial. H owever ,  ins u ch cases, the us e ofa built - inpower  s upply,s uchas a batte ry or other  charg e st orage  device ,can li mit  t he shelf l i fe of tha t com ponentdu e to  un intend ed ( b l eedin g of )ele ctrical d i s ch a rg e. Thi s ma y occ ur  bya numbero f mechan ism s , inclu di ngc h emical an d physical m ech anism s .  An embodi m ento ft his i nventi on see ks to a v oid  t he prob lem o f shelf l ife limit a tio nthat  may beas soci at edwi th on-board pow er suppl ies such a s batt eri e s.
F u rther,  i n a blasting  oper at i on it i s som etimesd esi rab leto l eav e el e ctrical devices in a bor ehol e for a l ong t ime.In  such ca s es t he use o f  an on-boardbattery may lim i t t h e
 and_in accordance_with the purposes of_the present_invention,_as embodied_and_broadly described therein,_the method of_this invention comprises the_formation of an_autologous_bioadhesive sealant comprising the steps of forming a platelet rich plasma or platelet poor_plasma_containing an_anticoagulant._The_platelet rich plasma or platelet_poor plasma is then divided_into two_portions and the first portion is restored so_that_it can coagulate,_thus forming a clot. The clot is triturated and_the resulting serum is collected. The_bioadhesive sealant composition_is_then_prepared by combining a_defined volume of the second portion_of platelet rich plasma or platelet_poor plasma with a sufficient volume of_serum causing the fibrinogen in the_second portion of platelet rich_plasma or_platelet poor plasma to be_converted to fibrin,_which then_solidifies in the_form of a gel. The use_of electrical/electronic devices_is growing rapidly in commercial blasting_operations._For example, some_detonators_now_rely on_Integrated circuits to_provide_functionality. Providing_electrical_power to such devices is therefore_necessary._This could be achieved in, for example_wireless initiation devices, using_a_built-in battery or charged_capacitor but providing the devices_“live” presents significant safety concerns since_the device_may itself_contain an explosive (detonators include a small charge of explosive) or_be positioned within or in proximity_to an explosive during_use. Addressing_these_concerns by specifically_designed_safety systems,_such as multiple layers of control at_the level_of circuit design, is possible. However,_this adds to design_complexity_and operation and, in turn, this_has implications with respect to cost,_efficiency and application. Furthermore, safe_operation_is_compromised if the safety system_itself fails.
The possible problems of providing_an explosive-containing initiation_device with a built-in power supply can_be_overcome by supplying the device in_multi-component_form, with the power supply containing_component_being_distinct from any component containing_explosive material. However, in such cases,_the use of a built-in power supply, such as_a battery or_other charge storage device, can_limit_the_shelf life of that component due to unintended (bleeding of)_electrical discharge._This may occur_by a number of mechanisms, including chemical and physical mechanisms._An embodiment of this invention seeks to_avoid the problem of shelf life limitation that may be associated_with on-board power supplies such as batteries.
Further, in_a blasting operation it is sometimes desirable_to leave electrical devices_in_a borehole for a long time. In_such_cases_the_use of an_on-board battery may_limit the