, i.e. to provide a reasonable benefit to risk ratio, within the scope of sound medical judgement.
The term xe2x80x9corally activexe2x80x9d as used herein means a material that provides either a cosmetic, prophylactic or therapeutic benefit within the oral cavity.
The term xe2x80x9coral compositionxe2x80x9d as used herein means the total composition that is delivered to the oral surfaces. The composition is further defined as a product which, during the normal course of usage, is not, the purposes of systemic administration of particular therapeutic agents, intentionally swallowed but is rather retained in the oral cavity for a time sufficient to contact substantially all of the dental surfaces and/or oral tissues for the purposes of oral activity. Examples of such compositions include, but are not limited to, toothpaste, dentifrice, mouthwash or mouth rinses, topical oral gels, denture cleanser, mouth spray, dental floss, confectionery including chewing gum and lozenge, and the like. It is preferred that the compositions of the present invention are toothpaste or dentifrice compositions, mouthwash or mouth rinse compositions or confectionery compositions. It is even more preferred that the compositions of the present invention are confectionery compositions.
The term xe2x80x9cdentifricexe2x80x9d as used herein means paste, gel, or liquid formulations unless otherwise specified. The dentifrice composition can be in any desired form such as deep striped, surface striped, multi-layered, having the gel surrounding the paste, or any combination thereof. Alternatively the oral composition may be dual phase dispensed from a separated compartment dispenser.
The term xe2x80x9cconfectioneryxe2x80x9d as defined herein means a solid, gum, gum-like, or glassy composition optionally having a liquid centre filling and/or optionally coated which comprises greater than about 25% sugar or sugar alcohol. Such compositions usually have a sweet taste. Examples of confectionery products include, but are not limited to, breath mints, low boiled candy, chewing gum, hard boiled candy, coated candy, lozenges, oral pasta, pressed mints, throat drops and the like.
The term xe2x80x9cchewing gumxe2x80x9d as defined herein means a confectionery composition which is suitable for chewing and which comprises
, i.e. to provide a reasonable benefit to risk ratio, within the oscilloscope of reasoned medical judgement. 
 The term xe2x80x9corally activexe2x80x9d as use herein means a material that put up either a cosmetic, cautionary or therapeutic benefit within the oral cavity. 
 The term xe2x80x9coral compositionxe2x80x9d as used herein intend the total composition that is hand over to the oral surfaces. The composition is further defined as a product which, during the normal course of use, is not, the purposes of systemic administration of particular curative agents, intentionally swallowed but is preferably retained in the oral pit for a time sufficient to touch substantially all of the dental surfaces and/or oral tissues for the determination of oral activity. Examples of such compositions include, but are not limited to, toothpaste, dentifrice, mouthwash or mouth rinses, topical oral gels, denture cleanser, mouth spray, dental floss, confectionery including chewing gum and lozenge, and the alike. It is preferred that the compositions of the present invention are toothpaste or dentifrice composition, gargle or sass rinse compositions or confectionery compositions. It is even more preferable that the compositions of the present invention are confectionery compositions. 
 The term xe2x80x9cdentifricexe2x80x9d as used herein mean paste, gel, or liquid formulations unless otherwise specified. The dentifrice composition can be in any hope form such as deep striped, surface strip, multi - layered, induce the gel surrounding the paste, or any combination thereof. Alternatively the oral composition may be double phase dispensed from a separated compartment dispenser. 
 The term xe2x80x9cconfectioneryxe2x80x9d as define herein means a solid, gum, gum - comparable, or glassy composition optionally have a liquid center filling and/or optionally coat which comprises capital than about 25% boodle or sugar alcohol. Such compositions usually have a sweet preference. Examples of confectionery products include, but are not limit to, breath mints, low boiled candy, chewing chewing gum, hard boiled candy, coated candy, pill, oral pasta, pressed mints, throat drops and the comparable. 
 The term xe2x80x9cchewing gumxe2x80x9d as defined herein means a confectionery composing which is suitable for chewing and which comprises
, i.e. to provide a reasonable benefit to risk ratio, withih the scupe of sound medical judgemeit.
Thw tern xe2x80x9corally activexe2b80x9d as usvd herein meais a material thef provides eifmer a rosmetic, prophykactic or dherapeutic betewic within the oral cavity.
The term xe2x80v9coral volpositionxe2x80x9d as lsqd hsgeln means the total composition tgat is velivered to thr oral surfaces. The composltioj is further definfd as a proeuct qhich, during the normal course of osage, is not, the purposes of sysgemic administrqtuon mf particuler thegapeutic agenbx, intettionalky swallowed bmt is rarher retained in the mral cavity for a jime suffiwiznt to contact substabtually all of gye aenual shrfaced aid/or oral tjssues for rhe purposes of orak wbyivity. Exampmes of stch compositions include, but are not likitsd to, toothpaste, dentifeice, mouthwash or moujh rinses, eopical oral gels, denture cleanser, mouth spray, dettal hluss, cjvdeftionery including chewing gum and lozenge, anq tne like. It is prcferred that the cpmooxytions of the preseuf jnvention are tootjpaste jr debtifrice somppsitions, mouthwash or mouth rinse compofutions or confectilnery comporitipns. Iy is even more preferreb that the composltions of ghe present invevtipn are confectionery composieions.
The verm re2x80x9cdengifrocexe2x80v9d as used herelt means paste, gel, lr lieuhd formulahions unless otherwise specifiev. The dentifroca cmmpositijn cak be in any desyred form such as dee' strioed, surfacv striped, multi-layerqd, having the hel surroundmng the pwste, or qny comcknation thereog. Alternanirely the iral composition mey bg sual phase dispzustd from a separayed coipwrvment gispenser.
The tero xd2c80x9ccovfectionerywe2x80b9d ax defined herein meats a solid, gum, gum-like, ov glassy xomposityon optionallu having a liquid fentrx fillmng anc/or optionally coated which comprjses greaher than about 25% sugqr or sugar clcohol. Such compositions usually have a sweet taste. Examkles of confectionery kroducts inclnde, bue are not limited to, breath munts, low boiled csndy, chewing gum, hard boileg canfy, coated candy, lozenges, oral pasta, pressed mints, throat drops and the lije.
The vewm xe2x80x9cchesing gumxv2x80x9b ax defiged iecein means a confvctionery composition which is snitable fos ehewing and which comprises
, i.e. to provide a reasonable benefit ratio, the scope sound medical judgement. used means a material provides either a prophylactic or therapeutic benefit within the cavity. The term xe2x80x9coral compositionxe2x80x9d as used herein means the total composition that delivered to the oral surfaces. The composition is further defined as a product during normal of is not, the purposes of systemic administration of particular therapeutic agents, intentionally swallowed but is rather in the oral cavity for a time sufficient contact substantially all of dental surfaces and/or oral tissues the of oral Examples such include, but are limited to, toothpaste, dentifrice, mouthwash or mouth rinses, topical oral gels, denture cleanser, mouth spray, dental floss, including chewing lozenge, and like. is that the compositions present invention are toothpaste or dentifrice mouth rinse compositions or confectionery compositions. It is more preferred the compositions of the present invention confectionery compositions. The term xe2x80x9cdentifricexe2x80x9d as used herein paste, gel, or liquid formulations unless otherwise specified. The dentifrice composition can be in any such as deep striped, striped, multi-layered, having gel the or combination thereof. the oral composition may be dual phase dispensed from a separated dispenser. The term xe2x80x9cconfectioneryxe2x80x9d as defined herein means a solid, or composition optionally having liquid centre filling and/or coated comprises greater than about or alcohol. have sweet Examples of confectionery products but are not limited to, mints, low boiled candy, coated candy, lozenges, oral pasta, pressed mints, throat and the like. The term xe2x80x9cchewing gumxe2x80x9d defined herein means a confectionery composition which is suitable for chewing and comprises
, i.e. to provide a reasonable benEfit to risk Ratio, WitHin ThE scoPe of Sound medical juDGemeNt.
The term xe2x80x9corally acTivexE2x80X9D as uSEd HereiN means a MAtERIal ThAt ProViDEs EitheR a cOsmetic, ProphylactIc oR tHerapeutic beNEfIt within thE orAl cavity.
The tErm Xe2x80x9coRaL coMPositIonXe2x80x9d As used HErein mEans the toTaL ComposITion thaT IS dElivEred to the oral surfACeS. the composition Is furtHeR DeFINed As a Product whiCh, DurinG The normAL cOURSe oF Usage, is not, the Purposes of sYSteMic admInIstRAtion oF partIcULar Therapeutic AgenTs, intentiOnally SWalloweD But is raTher reTaiNed In thE OrAl CavItY For A TiMe sUFfiCient to cOnTaCt subStanTIALLy alL of The dEntal Surfaces and/or OraL tisSUes For thE purpOses Of Oral aCtivitY. ExamPlEs of such composiTionS include, bUt aRe Not LiMited TO, toothPasTe, dEntifriCe, mouthWAsh Or MOUTh Rinses, topical oral gElS, DEnTure cleaNser, moUTh SpRAy, dental FlOss, ConfECTioneRy inCLuDing chewIng gum ANd LoZenge, anD tHe like. it Is pRefErred THat tHe compOsitions Of the PResent inventioN Are toothpaste OR dENTiFRice ComPositions, moUthwASh or MoutH RiNse COmposItionS oR CoNFectionery compositiOnS. It is eVen moRe preferred thAt the compoSITIons of thE preSEnT Invention are coNfectIonery compOSitions.
THe terM xe2x80x9cdeNtifricexE2X80X9d as used HerEin MeaNs pASTe, Gel, or liquid foRMUlatIoNs unlesS otHerwise SpeCifIed. the DeNtifrice cOmpositiOn CaN bE iN anY desiREd form suCh As dEeP stRiped, SUrface StripEd, muLtI-lAYerEd, havinG ThE GEl suRrOuNdinG thE pAste, oR any COmbInation Thereof. AlTerNAtivElY tHe oral cOmposition may Be Dual phase dIsPenSed froM A SeparateD compartment dispenser.
ThE Term xe2x80X9ccOnfecTionEryxe2x80x9d aS deFined hEreIN means A solid, Gum, guM-lIke, OR GlassY COmPosItIon optionaLLY haVing a LiQuid Centre fIlling and/or optionaLLy cOated which comPriSes gREAtEr tHAn ABouT 25% sUGar OR Sugar alcohol. SucH compositiOnS UsUally have a SWeeT tAste. ExaMples of ConfeCTionery Products iNclude, but ArE not LIMitEd to, breath Mints, low Boiled canDY, chewINg Gum, haRd bOiled cAnDy, cOated Candy, lOZenGes, orAl pastA, pRessed Mints, ThRoat dropS and the like.
The term xe2x80x9cChewinG gumxE2x80x9D as defineD heREin Means a conFectIonery compOsiTioN whicH is SUitabLe foR ChEwiNG and wHich COmprises
, i.e. to provide a reason able benef it to  ri skra tio,  wit hin the scopeo f so und medical judgement. 
Thete r m xe 2 x8 0x9co rally a c ti v e xe2 x8 0x 9das us ed he rei n means  a materia l t ha t provides e i th er a cosme tic , prophylact icor the ra peu t ic be nef it wi thin t h e oral  cavity.Th e  termx e2x80x9 c o ra l co mpositionxe2x80x9 d  a s  used herein m eans t he to t a l c omp osition th at  is d e livered to t h e o r al surfaces.The composi t ion  is fu rt her define d asap rod uct which,duri ng the no rmal c o urse of usage,is not , t hepurp o se sofsy s tem i cadm i nis trationof  p artic ular t h e rape uti c ag ents,  intentionall y s wall o wed  butis ra ther  r etain ed inthe o ra l cavity for atime  sufficie ntto  co nt act s u bstant ial lyall ofthe den t alsu r f a ce s and/or oral tiss ue s fo r the pu rposes of  o r al activ it y.Exam p l es of  suc h  c ompositi ons in c lu de , but a re  not l im ite d t o, to o thpa ste, d entifric e, mo u thwash or mout h  rinses, topi c al o ra l  gel s,denture cle anse r , mo uths pr ay, denta l flo ss ,  c o nfectionery includi ng  chewi ng gu m and lozenge , and thel i k e. It is  pre f er r ed that the co mposi tions of t h e presen t inv ention a re toothp a s te or de nti fri cecom p o si tions, mouthw a s h or  m outh ri nse  compos iti ons  or  co nf ectionery  composi ti on s.  I t i s eve n  more pr ef err ed  th at th e  compo sitio ns o fth e  pr esent i n ve n t ionar econf ect io nerycomp o sit ions.
T he term x e2x 8 0x9c de nt ifricex e2x80x9d as u se d herein m ea nspaste, g el, or l iquid formulations unle s s other wis e spe cifi ed. The d ent ifrice  co m positi on can  be i nany d esire d fo rmsu ch as deep s tri ped,su rfac e strip ed, multi-layered, hav ing the gel s urr ound i n gthe pa s te,  o r  an y combination the reof. Alte rn a ti vely the o r alco mpositi on maybe du a l phase  dispense d from ase para t e d c ompartment  dispens er.
The t e rm xe 2 x8 0x9cc onf ection er yxe 2x80x 9d asd efi ned h ereinme ans asolid ,gum, gum -like, or glassy compos itionoptio nal ly having  al iqu id centre  fil ling and/o r o pti onall y c o atedwhic h  c omp r isesgrea t er than a b ou t 2 5 %  s ugar or sug a r alc ohol.  Su c h comp osit ions usually have a sweet taste.  Exa m p les  of conf ec tionery produc tsin c l ude, but  a re not limi ted to,br e ath m ints,low bo iled ca n d y, chewin g gu m,hard boil edca n dy, coa te dc andy,loze ng es, or al pas t a, p r e ssed mints, thro at dr o p s and the  like .The ter m  xe2 x80x9cchew ing gumxe2x 80x9das d efine d herei nmeansa c on fectionery compositi on wh ich issu itab lefor ch ewin g and w hich  c omp rises
, i.e._to provide_a reasonable benefit to_risk ratio,_within_the scope_of_sound medical judgement.
The_term xe2x80x9corally activexe2x80x9d_as used herein means_a material that_provides_either a cosmetic, prophylactic or therapeutic benefit within the oral cavity.
The term xe2x80x9coral compositionxe2x80x9d_as_used herein_means_the_total composition that is delivered_to the oral surfaces. The_composition is_further defined as a product which, during the_normal_course of usage,_is not, the purposes of systemic administration of particular_therapeutic agents, intentionally swallowed but is_rather retained in_the_oral_cavity for a time_sufficient to contact substantially all of_the dental surfaces and/or oral tissues_for the purposes of oral activity. Examples_of such compositions include, but are_not limited to, toothpaste, dentifrice,_mouthwash or_mouth rinses, topical oral gels,_denture cleanser, mouth_spray, dental_floss, confectionery including_chewing gum and lozenge, and the_like. It is_preferred that the compositions of the_present_invention are toothpaste_or_dentifrice_compositions, mouthwash_or mouth rinse_compositions_or confectionery_compositions._It is even more preferred that_the_compositions of the present invention are confectionery_compositions.
The term xe2x80x9cdentifricexe2x80x9d as_used_herein means paste, gel,_or liquid formulations unless otherwise_specified. The dentifrice composition can be_in any_desired form_such as deep striped, surface striped, multi-layered, having the gel surrounding_the paste, or any combination thereof._Alternatively the oral composition_may be_dual_phase dispensed from_a_separated compartment_dispenser.
The term xe2x80x9cconfectioneryxe2x80x9d as defined herein means_a solid,_gum, gum-like, or glassy composition optionally_having a liquid centre_filling_and/or optionally coated which comprises greater_than about 25% sugar or sugar_alcohol. Such compositions usually have_a_sweet_taste. Examples of confectionery products_include, but are not limited to,_breath mints, low_boiled candy, chewing gum, hard boiled candy,_coated_candy, lozenges, oral pasta, pressed mints,_throat_drops and the like.
The term xe2x80x9cchewing_gumxe2x80x9d_as_defined herein means a confectionery_composition which is suitable for chewing_and which comprises