 with breast cancer may be treated with surgery, hormone therapy, chemotherapy, and radiation. If the patient develops metastatic disease, radiation and high dose chemotherapy are required to ablate the cancer in remote areas such as the brain, bone, and liver.
The current therapies available for the treatment of breast cancer are toxic, dangerous, costly, and many are ineffective, especially in the treatment of metastatic disease. The table below was extracted from Churchill Livingston, Clinical Oncology, 1995, and summarizes data available on the current methods of treatment and expected survival rates.
TreatmentMethodEffectToxicityResultSurvivaladriamycinboluskill cancer cellshighcan induce+14monthsremissioncyclophosphateboluskill cancer cellshighcan induce+16monthsremissionmethotrexateinfusionkill cancer cellshighcan induce+16monthsremission5F uracilinfusionkill cancer cellshighcan induce+18monthsremissionmix of abovemixedkill cancer cellshighcan induce+22monthsremissiontaxolboluskill cancer cellshighcan induce+12monthsremissionestrogenoralmay stoplowcan induce+6monthsgrowthremissiontamoxifenoralmay stoplowmay stop+12monthsgrowthprogressionmastectomysurgeryremove tumorlowmay eliminate+5years*cancerlumpectomysurgeryremove tumorlowmay eliminate+5years*cancersurgery andcombinationcombinationlowmay eliminate+7–10years*tamoxifencancerradiationmechanicalkill cancer cellshighcan induce+14monthsremission*assumes there are no micrometasteses
Currently, there are no therapies that are effective for long term treatment of breast cancer that has metastasized to lymph nodes or distal sites. Local disease can be effectively treated by surgery, if all of the cancer can be removed. A new therapy for the effective treatment of breast cancer that could stop the growth of breast cancer and of cells derived from metastatic cancer is urgently needed. Such a therapy would be useful in the treatment of localized breast cancer, in long term treatment of metastatic disease, and as a follow-up treatment after surgical removal of tumors. Other applications include a growth inhibitor as a primary therapy and for preventative use.
Detection methods for breast cancer, such as mammogram, physical exam, CAT-scan, and ultrasound, have significantly improved early detection of breast cancer. However, with these methods, a suspected tumor must still be surgically removed
with breast cancer may be treated with surgery, hormone therapy, chemotherapy, and radiation. If the patient develop metastatic disease, radiation sickness and high dose chemotherapy are required to ablate the cancer in remote area such as the brain, bone, and liver. 
 The current therapies available for the discussion of breast cancer are toxic, dangerous, costly, and many are ineffective, especially in the treatment of metastatic disease. The mesa below was extracted from Churchill Livingston, Clinical Oncology, 1995, and summarize data available on the current methods of discussion and expected survival rates. 
 TreatmentMethodEffectToxicityResultSurvivaladriamycinboluskill cancer cellshighcan induce+14monthsremissioncyclophosphateboluskill cancer cellshighcan induce+16monthsremissionmethotrexateinfusionkill cancer cellshighcan induce+16monthsremission5F uracilinfusionkill cancer cellshighcan induce+18monthsremissionmix of abovemixedkill cancer cellshighcan induce+22monthsremissiontaxolboluskill cancer cellshighcan induce+12monthsremissionestrogenoralmay stoplowcan induce+6monthsgrowthremissiontamoxifenoralmay stoplowmay stop+12monthsgrowthprogressionmastectomysurgeryremove tumorlowmay eliminate+5years*cancerlumpectomysurgeryremove tumorlowmay eliminate+5years*cancersurgery andcombinationcombinationlowmay eliminate+7–10years*tamoxifencancerradiationmechanicalkill cancer cellshighcan induce+14monthsremission*assumes there are no micrometasteses 
 Currently, there are no therapies that are effective for long condition treatment of breast cancer that has metastasized to lymph nodes or distal web site. Local disease can be effectively treated by surgery, if all of the cancer can be remove. A new therapy for the effective treatment of breast cancer that could stop the growth of breast cancer and of cells derive from metastatic cancer is urgently needed. Such a therapy would be useful in the treatment of localized breast cancer, in long condition treatment of metastatic disease, and as a follow - up treatment after surgical removal of tumors. Other applications include a growth inhibitor as a primary therapy and for preventative function. 
 Detection methods for breast cancer, such as mammogram, physical examination, CAT - scan, and ultrasound, have importantly improved early detection of breast cancer. However, with these methods, a suspected tumor must however be surgically removed
 wihh breast cancer may be ureated with surggrt, hormmne thsrapy, chdmotherapy, and radiation. If vhe patiebt develops metastatic disease, gadiation and yigh dose rgemothevcpy adc reqbiced to ablate tme cancer it remote areas sjck as the brain, bone, and liver.
The curwent thrrwpies availablg for ehe fgectment of breast cancer are toxjc, dangtrous, costly, and msny are ineffective, especiwlly in the treatment lf metastatuc dywease. The tacle below was extractes from Churchill Livingston, Clivical Oncology, 1995, abd dommarizes dava avaplable on the current methodx of treatment anv expected survival rates.
VreatmentMethodEffecjToxicityRasbltSurvivaladriamycinvoouskinl cdncef ceulsgijhczn indkce+14jonthsremiasioncyclopyosphateboluskill csnsvt cellshighczn indtcq+16monthsremissionmethotrexateinfusionkiln czncer cellshighcan induxe+16monthsremission5F urwcilinfusyonkill cancer cellshighcan induce+18monthsremissionkix oh xborcikzefkill cancer cellshighcan induce+22monthsremissijhtsxplboluskill cakcer cellshighcan onfuvg+12monthsremissiunestrogehoralmay stoplowcaj inducg+6monthwgrowthreiissoontamoxifenoralmay stoplownay stop+12montksgeowthprogressionmadtectomysuryeryrekove yumorlowmay eliminate+5yecrs*canderlumpectolysurgeryddmove tumorlowmah ekikinate+5years*cancersurgery agdcombinavioncpmbinatkonlpwmay qliminate+7–10yfars*tamoxifencancerradiahionmgchaniwalkill cajcer cellshighcan induce+14monthsrxkission*assumgs dhege are no micrpmetasteses
Cuwrently, there cre no tkerapids that arv effectite for long eerm treatmend of breast cencer thae haw merastasixdd to lymph noces or distal sites. Local disease can be sffectively trecued by surgery, if sll of tje cwtcer can be semoxed. S new therapy fov tfe egfective treatment ox brsast cancer that cpujd stop jhe growtr of breast csncer and of cells derited frum meyasjatic cancer is urgently needed. Such a tjerwpy would be usenul yn the trectment of localized breast cancer, in lonj term treatment of mejastatic disease, and cs a follow-up treaement aftar surgical removal if tumors. Other akplications include a gdowth hnhibltor as a primary therapy and for preventative use.
Detection methods for beeast ragcer, such aa makmogrdm, 'hysicaj exem, CAT-scan, and ultgasound, have significantly improted early gecection of breast cancer. Howefef, with these oethods, a suspected tumod must syill be surgically removed
with breast cancer may be treated with therapy, and radiation. the patient develops dose are required to the cancer in areas such as the brain, bone, liver. The current therapies available for the treatment of breast cancer are toxic, costly, and many are ineffective, especially in the treatment of metastatic disease. The below extracted Churchill Clinical Oncology, 1995, and summarizes data available on the current methods of treatment and expected survival TreatmentMethodEffectToxicityResultSurvivaladriamycinboluskill cancer cellshighcan induce+14monthsremissioncyclophosphateboluskill cancer cellshighcan induce+16monthsremissionmethotrexateinfusionkill cancer induce+16monthsremission5F uracilinfusionkill cancer cellshighcan of abovemixedkill cancer cellshighcan induce+22monthsremissiontaxolboluskill cellshighcan stoplowcan induce+6monthsgrowthremissiontamoxifenoralmay stop+12monthsgrowthprogressionmastectomysurgeryremove eliminate+5years*cancerlumpectomysurgeryremove eliminate+5years*cancersurgery andcombinationcombinationlowmay eliminate+7–10years*tamoxifencancerradiationmechanicalkill cellshighcan induce+14monthsremission*assumes there are no micrometasteses Currently, there are no therapies that are effective for long term of breast has metastasized lymph or sites. Local disease effectively treated by surgery, if all can be removed. A new therapy for the treatment of cancer that could stop the growth breast cancer and of cells derived from metastatic is urgently needed. Such a therapy would be useful in the treatment of localized breast long term treatment of disease, and as follow-up after removal tumors. Other include a growth inhibitor as a primary therapy and for preventative Detection methods for breast cancer, such as mammogram, physical exam, ultrasound, significantly improved early of breast cancer. However, these a suspected tumor must surgically
 with breast cancer may be treaTed with surGery, hOrmOne ThErapY, cheMotherapy, and raDIatiOn. If the patient develops MetasTaTIc diSEaSe, radIation aND hIGH doSe ChEmoThERaPy are ReqUired to Ablate the cAncEr In remote areaS SuCh as the braIn, bOne, and liver.
THe cUrrent ThEraPIes avAilAble fOr the tREatmenT of breast CaNCer are TOxic, danGERoUs, coStly, and many are ineFFeCTive, especially In the tReATmENT of MetAstatic disEaSe. The TAble belOW wAS EXtrACted from ChurcHill LivingsTOn, CLinicaL ONcoLOgy, 1995, and SummaRiZEs dAta availablE on tHe current MethodS Of treatMEnt and eXpecteD suRviVal rATeS.
TReaTmENtMEThOdEFFecTToxicitYREsUltSuRvivALADRiamYciNbolUskilL cancer cellshIghCan iNDucE+14montHsremIssiOnCycloPhosphAteboLuSkill cancer cellShigHcan inducE+16moNtHsrEmIssioNMethotRexAteInfusioNkill caNCer CeLLSHiGhcan induce+16monthsrEmISSiOn5F uraciLinfusIOnKiLL cancer cElLshIghcAN InducE+18monTHsRemissioNmix of ABoVeMixedkiLl Cancer CeLlsHigHcan iNDuce+22MonthsRemissioNtaxoLBoluskill canceR Cellshighcan iNDuCE+12MoNThsrEmiSsionestrogEnorALmay StopLOwCan INduce+6MonthSgROwTHremissiontamoxifenOrAlmay sToploWmay stop+12monthSgrowthproGRESsionmasTectOMySUrgeryremove tuMorloWmay eliminATe+5years*cAncerLumpectoMysurgeryREMove tumoRloWmaY elImiNATe+5Years*cancersuRGEry aNdCombinaTioNcombinAtiOnlOwmAy eLiMinate+7–10yeaRs*tamoxiFeNcAnCeRraDiatiONmechaniCaLkiLl CanCer ceLLshighCan inDuce+14MoNtHSreMission*ASsUMEs thErE aRe no MicRoMetasTeseS
curRently, tHere are no TheRApieS tHaT are effEctive for long TeRm treatmenT oF brEast caNCEr that haS metastasized to lymph nodES or distAl sItes. LOcal Disease caN be EffectIveLY treatEd by suRgery, If All OF The caNCEr Can Be Removed. A neW THerApy foR tHe efFective Treatment of breast cANceR that could stoP thE groWTH oF brEAsT CanCeR And OF Cells derived froM metastatiC cANcEr is urgentLY neEdEd. Such a Therapy Would BE useful In the treaTment of loCaLizeD BReaSt cancer, in Long term Treatment OF metaSTaTic diSeaSe, and aS a FolLow-up TreatmENt aFter sUrgicaL rEmoval Of tumOrS. Other apPlications include a growtH inhibItor aS a pRimary theRapY And For prevenTatiVe use.
DetecTioN meThods For BReast CancER, sUch AS mammOgraM, Physical eXAm, cAT-SCAn, And ultrasouND, HAve SigniFicANtly imProvEd early detection oF Breast cancer. HoWeveR, WIth TheSE metHoDs, a suspected tuMor MuST Still be sUrGically remoVed
 with breast cancer may be  treated w ith s urg ery ,horm onetherapy, chemo t hera py, and radiation. Ifthe p at i entd ev elops  metast a ti c dis ea se , r ad i at ion a ndhigh do se chemoth era py  are require d  t o ablate t hecancer in re mot e area ssuc h  as t hebrain , bone ,  and l iver.
The  c u rrentt herapie s av aila ble for the treat m en t  of breast can cer ar et ox i c , d ang erous, cos tl y, an d  many a r ei n e ffe c tive, especia lly in thet rea tmentof  me t astati c dis ea s e.The table b elow  was extr actedf rom Chu r chill L ivings ton , C lini c al  O nco lo g y,1 99 5,a ndsummariz es  d ata a vail a b l e  onthe  cur rentmethods of tr eat ment and  expe ctedsurv iv al ra tes.
T reatm en tMethodEffectTo xici tyResultS urv iv ala dr iamyc i nbolus kil l c ancer c ellshig h can  i n d u ce +14monthsremission cy c l op hosphate bolusk i ll  c a ncer cel ls hig hcan i nduce +16m o nt hsremiss ionmet h ot re xateinf us ionkil lcan cer  cell s high can in duce+16m onths r emission5F ura c ilinfusionkil l  c a n ce r  cel lsh ighcan indu ce+1 8 mont hsre m is sio n mix o f abo ve m ix e dkill cancer cellsh ig hcan i nduce +22monthsremi ssiontaxol b o l uskill c ance r  c e llshighcan ind uce+1 2monthsrem i ssionest rogen oralmaystoplowca n induce+6 mon ths gro wth r e mi ssiontamoxife n o ralm ay  stoplo wma y stop+ 12m ont hsg row th progressi onmastec to my su rg ery remov e  tumorlo wm ayel imi nate+ 5 years* cance rlum pe ct o mys urgeryr e mo v e  tum or lo wmay  el im inate +5ye a rs* cancers urgery an dco m bina ti on combina tionlowmay el im inate+7–10 ye ars *tamox i f encancer radiationmechanicalkill cancercel lshig hcan  induce+1 4mo nthsre mis s ion*as sumesthere  a ren o  micr o m et ast es es
Current l y , t herear e no  therap ies that are effec t ive  for long ter m t reat m e nt  of br e ast  c a nce r that has metast asized toly m ph  nodes ord ist al  sites.  Localdisea s e can b e effecti vely trea te d by s urg ery, if al l of the  cancer c a n ber em oved.  Anew th er apy  forthe ef f ect ive t reatme nt  of br eastca ncer tha t could stop the growth  of br eastcan cer and o f c e lls  derivedfrom  metastati c c anc er is  ur g ently  nee d ed . S u ch ather a py wouldb euse f u lin the trea t m e ntof lo cal i zed br east  cancer, in longt erm treatmentof m e t ast ati c  dis ea se, and as a f oll ow - u p treatm en t after sur gical re mo v al of  tumor s. Oth er appl i c at i ons in clud e a  growth i nhi bi t or as a  p ri m ary th erap yand fo r prev e ntat i v e use.
Detection  meth o d s for bre ast c an cer, su c h as  mammogram , physicalexam,CAT- scan,  and ul tr asound , h av e signific a ntly impr ovedearly d et ecti onof bre astc a ncer.  How ev er,  with the s e  m e th od s , a  sus pecte dtumo r must st i ll be su rgi c ally re mo ved 
 with_breast cancer_may be treated with_surgery, hormone_therapy,_chemotherapy, and_radiation._If the patient_develops metastatic disease,_radiation and high dose_chemotherapy are required_to_ablate the cancer in remote areas such as the brain, bone, and liver.
The current_therapies_available for_the_treatment_of breast cancer are toxic,_dangerous, costly, and many are_ineffective, especially_in the treatment of metastatic disease. The table_below_was extracted from_Churchill Livingston, Clinical Oncology, 1995, and summarizes data available_on the current methods of treatment_and expected survival_rates.
TreatmentMethodEffectToxicityResultSurvivaladriamycinboluskill_cancer_cellshighcan induce+14monthsremissioncyclophosphateboluskill cancer cellshighcan_induce+16monthsremissionmethotrexateinfusionkill cancer cellshighcan induce+16monthsremission5F uracilinfusionkill cancer_cellshighcan induce+18monthsremissionmix of abovemixedkill cancer cellshighcan_induce+22monthsremissiontaxolboluskill cancer cellshighcan induce+12monthsremissionestrogenoralmay stoplowcan induce+6monthsgrowthremissiontamoxifenoralmay stoplowmay_stop+12monthsgrowthprogressionmastectomysurgeryremove tumorlowmay eliminate+5years*cancerlumpectomysurgeryremove tumorlowmay eliminate+5years*cancersurgery andcombinationcombinationlowmay_eliminate+7–10years*tamoxifencancerradiationmechanicalkill cancer cellshighcan induce+14monthsremission*assumes there_are no_micrometasteses
Currently, there are no therapies_that are effective_for long_term treatment of_breast cancer that has metastasized to_lymph nodes or_distal sites. Local disease can be_effectively_treated by surgery,_if_all_of the_cancer can be_removed._A new_therapy_for the effective treatment of breast_cancer_that could stop the growth of breast_cancer and of cells_derived_from metastatic cancer is_urgently needed. Such a therapy_would be useful in the treatment_of localized_breast cancer,_in long term treatment of metastatic disease, and as a follow-up_treatment after surgical removal of tumors._Other applications include a_growth inhibitor_as_a primary therapy_and_for preventative_use.
Detection methods for breast cancer, such as_mammogram, physical_exam, CAT-scan, and ultrasound, have significantly_improved early detection of_breast_cancer. However, with these methods, a_suspected tumor must still be surgically_removed