 video capturing, playback of music or video files, game playing, and broadcast reception.
As one type of a terminal, there is a wireless sound device. The wireless sound device may be worn on a user's neck and interoperate with a mobile device to implement various functions. Since the wireless sound device is worn on a user's neck, the user does not need to hold it separately and also the wireless sound device is light. Therefore, it receives attention as a wearable device. Adding various functions to the wireless sound device is attempted and furthermore, researches on configuration and/or user experience (UX) optimized for the wireless sound device are in progress. 1. Field of the Invention
The herpes viruses include the Herpes Simplex virus (HSV), comprising two closely related variants designated types 1 (HSV-1) and 2 (HSV-2). These types cross react strongly but can be distinguished by neutralization titrations. HSV-1 and HSV-2 are responsible for a variety of human diseases, such as skin infections, genital herpes, vital encephalitis and the like.
HSV is a double-stranded DNA virus having a genome of about 150 to 160 kbp packaged within an icosahedral nucleocapsid enveloped in a membrane. The membrane includes a number of virus-specific glycoproteins, the most abundant of which are gB, gC, gD and gE, where gB and gD are cross-reactive between types 1 and 2.
It is a matter of great medical and scientific interest to provide safe and effective human vaccines against both HSV-1 and HSV-2 and, where infection has occurred, therapies for treatment of the disease.
One promising approach to the production of human vaccines against HSV has been the use of isolated glycoproteins, which have been shown to provide protection when injected into mice subsequently challenged with live virus. However, the availability of the Herpes Simplex glycoproteins has heretofore been primarily dependent upon the growth of the virus and the isolation of the membranous proteins. The problems of commercial production of the glycoproteins associated with the handling of a dangerous pathogen, the maintenance of the virus in cell culture, the isolation of the glycoproteins free of the vital genome or portions thereof, have substantially precluded the use of the glycoproteins as vaccines. It would therefore be desirable to provide human vaccines employing glycoproteins produced by methods other than by growth of the virus and isolation of the membranes proteins.
2. Description of the Relevant Literature
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video capturing, playback of music or video files, game acting, and air reception. 
 As one type of a terminal, there be a wireless good device. The wireless sound device may be worn on a drug user's neck and interoperate with a fluid device to implement various functions. Since the wireless sound device is worn on a drug user's neck, the user does not need to declare it separately and also the wireless sound device is light. Therefore, it receives care as a wearable device. Adding various functions to the wireless good device is attempted and furthermore, researches on shape and/or user experience (UX) optimize for the wireless sound device are in advancement. 1. Field of the Invention 
 The herpes viruses include the Herpes Simplex virus (HSV), comprising two close related variants designated types 1 (HSV-1) and 2 (HSV-2). These types cross react strongly but can be distinguished by neutralization titrations. HSV-1 and HSV-2 are responsible for a variety of human diseases, such as skin infections, genital herpes, vital encephalitis and the like. 
 HSV is a double - maroon DNA virus having a genome of approximately 150 to 160 kbp box within an icosahedral nucleocapsid enveloped in a membrane. The membrane includes a number of virus - specific glycoproteins, the about abundant of which are gB, gC, gD and gE, where gB and gD are crabbed - reactive between types 1 and 2. 
 It is a matter of great aesculapian and scientific interest to provide safe and effective human vaccines against both HSV-1 and HSV-2 and, where infection has occurred, therapy for treatment of the disease. 
 One promising approach to the production of human vaccines against HSV has been the use of isolated glycoprotein, which have been indicate to provide protection when injected into mouse subsequently challenged with live virus. However, the availability of the Herpes Simplex glycoprotein has heretofore been chiefly dependent upon the growth of the virus and the isolation of the membranous proteins. The problems of commercial production of the glycoprotein associated with the handling of a dangerous pathogen, the maintenance of the virus in cell culture, the isolation of the glycoprotein free of the vital genome or portions thereof, have well precluded the use of the glycoproteins as vaccine. It would therefore be desirable to provide human vaccines employing glycoproteins produced by methods other than by growth of the virus and isolation of the membranes proteins. 
 2. Description of the Relevant Literature 
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 vifeo capturing, playback on music or video files, jame plzying, ana broadcast reception.
As one vype of a terminal, there is a wkreless slund devuce. Uhe wireless sounv device may bs woru in a user's necl and intesoperate with d ooyile device to implement various funstions. Xijce the wirelefs sptnd svvlce is worn on a user's neck, the hser dots not need to holc it separately and also tje wlreless sound devife is light. Thewwfore, it recdives attention as a wgarable device. Adding various fuvctious to the wurwledv sound devmce is attempted akc furtvermore, researches on coifigyration and/or user ex'erience (UX) optimizeq for the wnreless sound device qrw in krograss. 1. Dieud kf tge Invfntmon
The herpss viruses unclude the Herpes Xiiikex virus (HSB), compwifing two closely related variants desigtatsd types 1 (HSV-1) and 2 (HSV-2). Rhese types cross reaft strongjy but can be distinguished by neutralization titsatiois. HSR-1 and FWV-2 are responsible for a variety of human diseafss, slch as skin infecbions, genital herprs, vojal encephalitks and ths like.
HSV is a douhle-stragded ENA virus havong a genome of about 150 to 160 jbp packaged qithin an icosahedxal nucleoca'sid emveloled in a membrane. The mzmbrans includes w number kw virus-specific elyboprmteins, the most abundant os which ace gB, gC, gD xnd bE, whewe gB and hD arc cross-reactive betaeen jypes 1 and 2.
It is a matter of great medical and scientific intgrevt no providz safe and effectivq human vaccings againsc both HSV-1 and HAV-2 and, xhere infectyon has occursgd, therapies hor treatient of rhe disdxse.
One promisimg approabh to rhe production of muman baccines againsc YSV has been thr ure jf ixojdted glycoprmteivs, dnich fave betu smowv to provide protection fhen injected into micr fubsequebtly chajlenged with kive virus. However, the evailauility of the Herpes Simplex glycoprotejns has hfrebofore been pwimavily dependent upon the growth of the virus and the iwolation of the mgmbranous proteins. Thg pvoblems of cpmmersial prodgction of the glycopeoteins associatec with the handling or a datgeroks pathogen, the maintenance of the virus in cell culture, the isolation of the glycoproteins frer of nhe rital gqnomx ur portions thervof, have substantially precluded the use oy the glycoproteins as vaccinrs. It would thetefore be desirable to probide humsn vaccines employing glycoprotrins produced by methods other tyan bg growng uf the virus and ixolatimn of the menbrakes proteins.
2. Ddsctiition of tje Rtlevcnt Literature
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video capturing, playback of music or video playing, broadcast reception. one type of wireless device. The wireless device may be on a user's neck and interoperate a mobile device to implement various functions. Since the wireless sound device is on a user's neck, the user does not need to hold it separately also wireless device light. Therefore, it receives attention as a wearable device. Adding various functions to the wireless sound is attempted and furthermore, researches on configuration and/or experience (UX) optimized for wireless sound device are in 1. of the The viruses the Herpes Simplex (HSV), comprising two closely related variants designated types 1 (HSV-1) and 2 (HSV-2). These types cross react but can by neutralization HSV-1 HSV-2 responsible for a human diseases, such as skin infections, encephalitis and the like. HSV is a double-stranded virus having genome of about 150 to 160 packaged within an icosahedral nucleocapsid enveloped in a The membrane includes a number of virus-specific glycoproteins, the most abundant of which are gB, and gE, where gB gD are cross-reactive types and It a matter great medical and scientific interest to provide safe and effective human against both HSV-1 and HSV-2 and, where infection has occurred, treatment the disease. One approach to the production human against HSV has been of glycoproteins, shown provide when injected into mice challenged with live virus. However, availability of the Herpes primarily dependent upon the growth of the virus the isolation of the membranous proteins. The of commercial production of the glycoproteins associated with the handling of a pathogen, the the virus in cell culture, the isolation of glycoproteins free of the genome or portions thereof, have substantially precluded the use the as vaccines. would therefore be to provide human employing glycoproteins produced other than growth the of the membranes proteins. 2. Description the Literature Eber
 video capturing, playback of mUsic or videO fileS, gaMe pLaYing, And bRoadcast receptIOn.
As One type of a terminal, therE is a wIrELess SOuNd devIce. The wIReLESs sOuNd DevIcE MaY be woRn oN a user's Neck and intEroPeRate with a mobILe Device to imPleMent various fUncTions. SInCe tHE wireLesS sounD devicE Is worn On a user's nEcK, The useR Does not NEEd To hoLd it separately and ALsO The wireless souNd deviCe IS lIGHt. THerEfore, it recEiVes atTEntion aS A wEARAblE Device. Adding vArious functIOns To the wIrEleSS sound DevicE iS AttEmpted and fuRtheRmore, reseArches ON configURation aNd/or usEr eXpeRienCE (Ux) oPtiMiZEd fOR tHe wIRelEss sound DeViCe are In prOGRESs. 1. FiEld Of thE InveNtion
The herpeS viRuseS IncLude tHe HerPes SImPlex vIrus (HSv), compRiSing two closely rElatEd variantS deSiGnaTeD typeS 1 (hSV-1) and 2 (hSV-2). theSe types Cross reACt sTrONGLy But can be distinguisHeD BY nEutralizAtion tITrAtIOns. HSV-1 anD HsV-2 aRe reSPOnsibLe foR A vAriety of Human dISeAsEs, such aS sKin infEcTioNs, gEnitaL HerpEs, vitaL encephaLitis ANd the like.
HSV is A Double-strandeD dNa VIrUS havIng A genome of abOut 150 tO 160 Kbp pAckaGEd WitHIn an iCosahEdRAl NUcleocapsid envelopeD iN a membRane. THe membrane incLudes a numbER OF virus-spEcifIC gLYcoproteins, the Most aBundant of wHIch are gB, GC, gD aNd gE, wherE gB and gD aRE Cross-reaCtiVe bEtwEen TYPeS 1 and 2.
It is a mattER Of grEaT medicaL anD scientIfiC inTerEst To Provide saFe and effEcTiVe HuMan VacciNEs againsT bOth hSv-1 anD HSV-2 aND, where InfecTion HaS oCCurRed, therAPiES For tReAtMent Of tHe DiseaSe.
OnE ProMising aPproach to The PRoduCtIoN of humaN vaccines agaiNsT HSV has beeN tHe uSe of isOLAted glycOproteins, which have been sHOwn to prOviDe proTectIon when inJecTed intO miCE subseQuentlY chalLeNgeD WIth liVE ViRus. hoWever, the avAILabIlity Of The HErpes SiMplex glycoproteins HAs hEretofore been PriMariLY DePenDEnT UpoN tHE grOWTh of the virus and The isolatiOn OF tHe membranoUS prOtEins. The ProblemS of coMMercial ProductioN of the glyCoProtEINs aSsociated wIth the haNdling of a DAngerOUs PathoGen, The maiNtEnaNce of The virUS in Cell cUlture, ThE isolaTion oF tHe glycopRoteins free of the vital geNome or PortiOns Thereof, haVe sUBstAntially pReclUded the use Of tHe gLycopRotEIns as VaccINeS. It WOuld tHereFOre be desiRAbLe tO PRoVide human vaCCINes EmploYinG GlycopRoteIns produced by methODs other than by gRowtH OF thE viRUs anD iSolation of the mEmbRaNES proteinS.
2. DEscription oF the ReleVaNT LiteRature
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 video capturing, playback  of musicor vi deo  fi le s, g ameplaying, and b r oadc ast reception.
As onetypeof a te r mi nal,there i s  a w ire le ss  so un d  d evice . T he wire less sound  de vi ce may be wo r non a user' s n eck and inte rop eratewi tha  mobi ledevic e to i m plemen t various  f u nction s . Since t he  wir eless sound devic e  i s  worn on a use r's ne ck ,  t h e  us erdoes not n ee d toh old its ep a r a tel y  and also the  wireless s o und  devic eisl ight.There fo r e,it receives  att ention as  a wea r able de v ice. Ad ding v ari ous  fun c ti on s t ot hew ir ele s s s ound dev ic eis at temp t e d andfur ther more,  researches o n c onfi g ura tionand/o r us er  expe rience  (UX)  o ptimized for th e wi reless so und  d evi ce  arei n prog res s.1. Fiel d of th e  In ve n t i on 
The herpes viruse si n cl ude theHerpes Si mp l ex virus  ( HSV ), c o m prisi ng t w ocloselyrelate d  v ar iants d es ignate dtyp es1 (HS V -1)and 2(HSV-2).  Thes e  types cross r e act stronglyb ut c an be d ist inguished b y ne u tral izat i on  ti t ratio ns. H SV - 1a nd HSV-2 are respon si ble fo r a v ariety of hum an disease s , such asskin in f ections, genit al he rpes, vita l  encepha litis  and the  like.
HS V is a dou ble -st ran ded D NA  virus having a  gen om e of ab out  150 to  16 0 k bppac ka ged withi n an ico sa he dr al  nu cleoc a psid env el ope dina mem b rane.The m embr an ei ncl udes an um b e r of  v ir us-s pec if ic gl ycop r ote ins, th e most ab und a nt o fwh ich are  gB, gC, gD a nd  gE, where  g B a nd gDa r e cross- reactive between types1  and 2. 
It  is a  mat ter of gr eat  medic ala nd sci entifi c int er est t o pro v i de  sa fe  and effec t i vehuman  v acci nes aga inst both HSV-1 an d  HS V-2 and, wher e i nfec t i on  ha s  o c cur re d , t h e rapies for trea tment of t he di sease.
One pro mi sing ap proachto th e  produc tion of h uman vacc in es a g a ins t HSV hasbeen the  use of i s olate d  g lycop rot eins,wh ich  have  beens how n toprovid eprotec tionwh en injec ted into mice subsequen tly ch allen ged  with liv e v i rus . However , th e availabi lit y o f the  He r pes S impl e xgly c oprot eins has heret o fo reb e en  primarilyd e p end ent u pon the gr owth  of the virus and the isolationof t h e  me mbr a nous  p roteins. The p rob le m s  of comm er cial produc tion ofth e  glyc oprote ins as sociate d wi t h thehand lin g of a da nge ro u s patho ge n, the ma inte na nce of  the v i rusi n  cell culture, t he is o l ation ofthe g ly coprote i ns f ree of the  vital geno me orport ionsthereof ,have s ubs ta ntially pr e cluded th e use  of the  g lyco pro teinsas v a c cines . It  w oul d therefo r e  b e  d es i rab le t o pro vi de h uman vacc i nes empl oyi n g glyco pr ote i n s prod u ce d by methods  ot her t h a n by growt h  oft he virus  and i solati on of t h e m em branespro t e ins.
2. D escriptio n  of  t he R elevantLi tera tu reEb er
 video_capturing, playback_of music or video_files, game_playing,_and broadcast_reception.
As_one type of_a terminal, there_is a wireless sound_device. The wireless_sound_device may be worn on a user's neck and interoperate with a mobile device_to_implement various_functions._Since_the wireless sound device is_worn on a user's neck,_the user_does not need to hold it separately and_also_the wireless sound_device is light. Therefore, it receives attention as a_wearable device. Adding various functions to_the wireless sound_device_is_attempted and furthermore, researches_on configuration and/or user experience (UX)_optimized for the wireless sound device_are in progress. 1. Field of the_Invention
The herpes viruses include the Herpes_Simplex virus (HSV), comprising two_closely related_variants designated types 1 (HSV-1)_and 2 (HSV-2)._These types_cross react strongly_but can be distinguished by neutralization_titrations. HSV-1 and_HSV-2 are responsible for a variety_of_human diseases, such_as_skin_infections, genital_herpes, vital encephalitis_and_the like.
HSV_is_a double-stranded DNA virus having a_genome_of about 150 to 160 kbp packaged_within an icosahedral nucleocapsid_enveloped_in a membrane. The_membrane includes a number of_virus-specific glycoproteins, the most abundant of_which are_gB, gC,_gD and gE, where gB and gD are cross-reactive between types_1 and 2.
It is a matter_of great medical and_scientific interest_to_provide safe and_effective_human vaccines_against both HSV-1 and HSV-2 and, where_infection has_occurred, therapies for treatment of the_disease.
One promising approach to_the_production of human vaccines against HSV_has been the use of isolated_glycoproteins, which have been shown_to_provide_protection when injected into mice_subsequently challenged with live virus. However,_the availability of_the Herpes Simplex glycoproteins has heretofore been_primarily_dependent upon the growth of the_virus_and the isolation of the membranous_proteins._The_problems of commercial production of_the glycoproteins associated with the handling_of a dangerous pathogen, the maintenance of the virus_in cell culture,_the isolation of the glycoproteins_free_of_the vital genome or portions thereof, have substantially precluded the_use of_the glycoproteins as_vaccines. It would therefore be desirable to provide human vaccines_employing glycoproteins produced by methods other than_by growth of the virus and isolation of the membranes proteins.
2._Description of the Relevant Literature
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