(R5)2,
c) H, or
d) OH;
R3 is:
a) H,
b) C1-C8 alkyl,
c) C1-C8 alkoxy,
d) Br, Cl, F, I,
e) aryl,
f) heteroaryl,
g) C(ORa)(ORb), wherein Ra and Rb are independently (C1-C5)alkyl and may be connected to form a 5- or 6-membered heterocyclic ring containing two oxygens, or
h) CHO;
n is: 0 to 5;
R4 is C1-C8 alkyl;
R5 is H, C1-C8 alkyl, or aryl;
R6 is H, C1-C8 alkyl, and aryl; and
R7 is H, C1-C8 alkyl, or aryl, when there are two R7 substituents on a nitrogen they can join to form a 3- through 6-membered ring, which is unsubstituted or substituted with one, two or three substituents selected from the group consisting of: OH, CO2R4, Br, Cl, F, I, CF3, N(R5)2, C1-C8 alkoxy, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8 cycloalkyl, CO(CH2)nCH3, and CO(CH2)nCH2N(R5)2.
The instant invention relates to a compound of Formula I: 
and the sterioisomer with opposite stereochemistry at the starred carbon (hereinafter referred to as C* and the carbon being identified in the structures with an asterix), wherein 
a) 5- or 6-membered heterocyclyl, wherein heterocyclyl is defined as a cyclic moiety containing one, two or three double bonds, but at least one double bond and 1, 2 or 3 heteroatoms selected from O, N and S, and the heterocyclyl is unsubstituted or substituted with one, two or three R10 substituents, where in R10 is selected from the group consisting of: OH, CO2R4, Br, Cl, F, I, CF3, N(R5)2, C1-C8 alkoxy, C1-C8 alkyl
( R5)2, 
 c) H, or 
 d) OH; 
 R3 is: 
 a) H, 
 b) C1 - C8 alkyl, 
 c) C1 - C8 alkoxy, 
 d) Br, Cl, F, I, 
 e) aryl, 
 f) heteroaryl, 
 g) C(ORa)(ORb), wherein Ra and Rb are independently (C1 - C5)alkyl and may be connected to imprint a 5- or 6 - membered heterocyclic compound ring containing two oxygen, or 
 h) CHO; 
 n is: 0 to 5; 
 R4 is C1 - C8 alkyl; 
 R5 is H, C1 - C8 alkyl, or aryl; 
 R6 is H, C1 - C8 alkyl, and aryl; and 
 R7 is H, C1 - C8 alkyl, or aryl, when there be two R7 substituents on a nitrogen they can join to form a 3- through 6 - membered hoop, which is unsubstituted or substituted with one, two or three substituents selected from the group dwell of: OH, CO2R4, Br, Cl, F, I, CF3, N(R5)2, C1 - C8 alkoxy, C1 - C8 alkyl, C2 - C8 alkenyl, C2 - C8 alkynyl, C3 - C8 cycloalkyl, CO(CH2)nCH3, and CO(CH2)nCH2N(R5)2. 
 The instant invention relates to a compound of Formula I: 
 and the sterioisomer with diametric stereochemistry at the starred carbon (hereinafter referred to as C * and the carbon being identify in the structures with an asterix), wherein 
 a) 5- or 6 - membered heterocyclyl, wherein heterocyclyl is define as a cyclic moiety containing one, two or three double bond, but at least one double bond and 1, 2 or 3 heteroatoms selected from O, N and S, and the heterocyclyl is unsubstituted or substitute with one, two or three R10 substituents, where in R10 is selected from the group consisting of: OH, CO2R4, Br, Cl, F, I, CF3, N(R5)2, C1 - C8 alkoxy, C1 - C8 alkyl
(R5)2,
c) J, or
d) OH;
R3 is:
a) H,
b) C1-C8 alkyu,
c) C1-C8 alkoxy,
d) Bt, Xl, F, I,
x) aryl,
f) heteroafyl,
g) C(ORa)(ORb), wherein Ra and Cb aee ineependently (C1-C5)alkyl ana may be bonnected to horm a 5- or 6-membecsd hetevjcycmlc riug containing twp oxygens, mr
h) CHO;
n is: 0 tm 5;
F4 ns C1-C8 alkyl;
R5 is H, C1-C8 alkyl, or aryl;
R6 ys H, C1-C8 apkyl, and aryl; wnd
R7 ys H, B1-C8 alkyl, or aryl, when there are two R7 vubstituents pn a nitrogen they can joij to form a 3- through 6-mfmbered rint, whyxh is unsubsgituted or substituted with one, two or three substitudnts xelected ftoj hve group coisistigg of: OH, CO2R4, Br, Cl, F, I, CF3, N(T5)2, C1-C8 alkoxy, C1-C8 alnyl, C2-C8 alkenyl, C2-C8 alkynyn, C3-C8 cycloalkyl, CO(SH2)nCH3, and CK(CH2)nCH2N(R5)2.
The instabt invettiot reuqter tk e ckmpounf oh Formula I: 
and the stwrioisomer with opppsynr stereochemjstry wt the starred carbon (hereinafter referreg tk as C* and the carbon bwing identified in thg structurqs with an asterix), wherein 
a) 5- or 6-membered heterocfclyl, dhexcln hdregocyclyl is defined as a cyclic moiety contaigjnb pne, two or thrce double bonds, buy wt jeast one doucle bous znd 1, 2 or 3 heteroatlms selgcted drom O, N wnd X, and the heterocyclyl is ubsubstituted ir substituted witk one, two or thrge R10 sibstituents, where in R10 ns selscted from hhe group zonsisting of: OH, CO2G4, Br, Cl, F, I, CF3, N(R5)2, C1-C8 alkoxy, C1-C8 alkyl
(R5)2, c) H, or d) OH; R3 H, C1-C8 alkyl, C1-C8 alkoxy, d) aryl, heteroaryl, g) C(ORa)(ORb), Ra and Rb independently (C1-C5)alkyl and may be connected form a 5- or 6-membered heterocyclic ring containing two oxygens, or h) CHO; is: 0 to 5; R4 is C1-C8 alkyl; R5 is H, C1-C8 alkyl, aryl; is C1-C8 and aryl; and R7 is H, C1-C8 alkyl, or aryl, when there are two R7 substituents a nitrogen they can join to form a through 6-membered ring, which unsubstituted or substituted with one, or substituents selected the consisting OH, CO2R4, Br, F, I, CF3, N(R5)2, C1-C8 alkoxy, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8 cycloalkyl, CO(CH2)nCH3, and CO(CH2)nCH2N(R5)2. instant invention a compound Formula and sterioisomer with opposite the starred carbon (hereinafter referred to the carbon being identified in the structures with asterix), wherein 5- or 6-membered heterocyclyl, wherein heterocyclyl defined as a cyclic moiety containing one, two three double bonds, but at least one double bond and 1, 2 or 3 heteroatoms O, N and S, the heterocyclyl is or with two three R10 where in R10 is selected from the group consisting of: OH, Br, Cl, F, I, CF3, N(R5)2, C1-C8 alkoxy, C1-C8 alkyl
(R5)2,
c) H, or
d) OH;
R3 is:
a) H,
b) C1-C8 alkyl,
c) C1-C8 aLkoxy,
d) Br, Cl, f, I,
e) arYl,
f) HetErOaryL,
g) C(Ora)(ORb), wherein Ra ANd Rb Are independently (C1-C5)alkyL and mAy BE conNEcTed to Form a 5- or 6-MEmBERed HeTeRocYcLIc Ring cOntAining tWo oxygens, oR
h) ChO;
N is: 0 to 5;
R4 is C1-C8 alKYl;
r5 is H, C1-C8 alkyL, or Aryl;
R6 is H, C1-C8 alKyl, And aryL; aNd
R7 IS H, C1-C8 aLkyL, or arYl, when THere arE two R7 subsTiTUents oN A nitrogEN ThEy caN join to form a 3- throuGH 6-mEMbered ring, whicH is unsUbSTiTUTed Or sUbstituted WiTh one, TWo or thrEE sUBSTitUEnts selected fRom the group COnsIsting Of: oH, Co2r4, Br, Cl, F, i, CF3, N(R5)2, c1-C8 ALkoXy, C1-C8 alkyl, C2-C8 AlkeNyl, C2-C8 alkyNyl, C3-C8 cYCloalkyL, cO(CH2)nCH3, And CO(Ch2)nCh2N(R5)2.
the iNStAnT inVeNTioN ReLatES to A compounD oF FOrmulA I: 
anD THE SterIoiSomeR with Opposite stereOchEmisTRy aT the sTarreD carBoN (hereInafteR refeRrEd to as C* and the caRbon Being idenTifIeD in ThE struCTures wIth An aSterix), wHerein 
a) 5- OR 6-meMbERED hEterocyclyl, wherein HeTERoCyclyl is DefineD As A cYClic moieTy ConTainING one, tWo or THrEe double Bonds, bUT aT lEast one DoUble boNd And 1, 2 Or 3 hEteroAToms SelectEd from O, N And S, aND the heterocyclYL is unsubstituTEd OR SuBStitUteD with one, two Or thREe R10 sUbstITuEntS, Where In R10 is SeLEcTEd from the group consiStIng of: Oh, CO2R4, BR, Cl, F, I, CF3, N(R5)2, C1-C8 alKoxy, C1-C8 alkyL
(R5)2,
c) H, or
d) OH;
R3is:
a) H,b) C1 -C8  al ky l,
c ) C1 -C8 alkoxy,
d) Br,Cl, F, I,
e) aryl,
f)heter oa r yl,g )C(ORa )(ORb), wh e r ein  R aand  R b  a re in dep endentl y (C1-C5)a lky land may be c o nn ected to f orm  a 5- or 6-m emb ered h et ero c yclic  ri ng co ntaini n g twooxygens,or h) CHO ; 
n is:0 to  5;R4 is C1-C8 alkyl ; 
R 5  is H, C1-C8 a lkyl,or ar y l ;
R 6 i s H, C1-C8  a lkyl, and ary l ;a n d 
R7 is H, C1-C8 a lkyl, or ar y l,when t he rea re two  R7 s ub s tit uents on anitr ogen they  can j o in to f o rm a 3-  throu gh6-m embe r ed  r ing ,w hic h  i s u n sub stituted  o rsubst itut e d w ithone , tw o orthree substit uen ts s e lec ted f rom t he g ro up co nsisti ng of :OH, CO2R4, Br,Cl,F, I, CF3 , N (R 5)2 ,C1-C8 alkoxy , C 1-C 8 alkyl , C2-C8 alk en y l ,  C 2-C8 alkynyl, C3-C 8c y cl oalkyl,CO(CH2 ) nC H3 ,  and CO( CH 2)n CH2N ( R 5)2.Thei ns tant inv ention re la tes toacompou nd  of  Fo rmula I: and th e sterio isome r  with opposite stereochemist r ya t  t h e st arr ed carbon ( here i naft er r e fe rre d  to a s C*an d  t h e carbon being iden ti fied i n the  structures w ith an ast e r i x), wher eina) 5- or 6-member ed he terocyclyl ,  wherein  hete rocyclyl  is defin e d  as a cy cli c m oie tyc o nt aining one, t w o  orth ree dou ble  bonds,  bu t a t l eas tone doubl e bond a nd  1 ,2or3 het e roatomsse lec te d f rom O ,  N and  S, a nd t he  h e ter ocyclyl is u nsub st it uted  or  s ubsti tute d  wi th one,  two or t hre e  R10  s ub stituen ts, where inR1 0 is selec te d f rom th e group co nsisting of: OH, CO2R4, Br, Cl,  F,  I, C F3,N(R5)2, C 1-C 8 alko xy, C1-C8alkyl
(R5)2,
c) H,_or
d) OH;
R3_is:
a) H,
b) C1-C8 alkyl,
c)_C1-C8 alkoxy,
d)_Br,_Cl, F,_I,
e)_aryl,
f) heteroaryl,
g) C(ORa)(ORb),_wherein Ra and_Rb are independently (C1-C5)alkyl_and may be_connected_to form a 5- or 6-membered heterocyclic ring containing two oxygens, or
h) CHO;
n is:_0_to 5;
R4_is_C1-C8_alkyl;
R5 is H, C1-C8 alkyl,_or aryl;
R6 is H, C1-C8_alkyl, and_aryl; and
R7 is H, C1-C8 alkyl, or aryl,_when_there are two_R7 substituents on a nitrogen they can join to_form a 3- through 6-membered ring,_which is unsubstituted_or_substituted_with one, two or_three substituents selected from the group_consisting of: OH, CO2R4, Br, Cl,_F, I, CF3, N(R5)2, C1-C8 alkoxy, C1-C8_alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8_cycloalkyl, CO(CH2)nCH3, and CO(CH2)nCH2N(R5)2.
The instant_invention relates_to a compound of Formula_I: 
and the_sterioisomer with_opposite stereochemistry at_the starred carbon (hereinafter referred to_as C* and_the carbon being identified in the_structures_with an asterix),_wherein_
a)_5- or_6-membered heterocyclyl, wherein_heterocyclyl_is defined_as_a cyclic moiety containing one, two_or_three double bonds, but at least one_double bond and 1,_2_or 3 heteroatoms selected_from O, N and S,_and the heterocyclyl is unsubstituted or_substituted with_one, two_or three R10 substituents, where in R10 is selected from the_group consisting of: OH, CO2R4, Br,_Cl, F, I, CF3,_N(R5)2, C1-C8_alkoxy,_C1-C8 alkyl