 social jet lag (eTable 3 in the Supplement).

Many of the associations of evening preference and social jet lag varied by sex, with stronger associations with adiposity observed for girls vs boys (Figure). Greater evening preference as a continuous measure was associated with higher indices on every measure of adiposity among girls; for example, girls had 0.16 kg/m2 (95% CI, 0.01-0.31 kg/m2; P =.03 for interaction) higher DXA fat mass index and 0.58 cm (95% CI, 0.12-1.03 cm; P =.04 for interaction) higher waist circumference for each point on the inverse-coded Morningness-Eveningness Scale for Children. Similarly, with each additional hour of social jet lag, girls had 0.45 kg/m2 (95% CI, 0.09-0.82 kg/m2; P =.01 for interaction) higher DXA fat mass index and 1.19 cm (95% CI, 0.04-2.35 cm; P =.21 for interaction) higher waist circumference. Meanwhile, neither evening preferences nor social jet lag was significantly associated with any measure of adiposity in boys; however, associations were generally in the same direction as observed in girls.

The associations of evening preferences with adiposity were attenuated slightly with adjustment for potential mediating factors: for example, the continuous association of evening preferences with total DXA fat mass index in girls was attenuated from 0.16 kg/m2 (95% CI, 0.01-0.31 kg/m2) to 0.15 kg/m2 (95% CI, 0.00-0.31 kg/m2) with adjustment for sleep duration (Figure) and was further attenuated to 0.14 kg/m2 (95% CI, −0.02 to 0.30 kg/m2) with adjustment for physical activity, television viewing, and diet quality (Table 2). However, social jet lag remained associated with DXA fat mass indices: per 1 hour of social jet lag, girls had a 0.46-kg/m2 (95% CI, 0.08-0.84 kg/m2) total DXA fat mass index and a 0.24-kg/m2 (95% CI, 0.05-0.44 kg/m2) trunk DXA fat mass index after adjustment for these potential mediators (Table 2).

social jet lag (eTable 3 in the Supplement). 

 Many of the associations of evening preference and social k stave varied by sex, with stronger association with adiposity observed for girls vs boy (number). Greater evening predilection as a continuous standard was associated with high indices on every measure of adiposity among daughter; for example, girls had 0.16 kg / m2 (95% CI, 0.01 - 0.31 kg / m2; P = .03 for interaction) higher DXA fat batch index and 0.58 cm (95% CI, 0.12 - 1.03 cm; phosphorus = .04 for interaction) higher waist circumference for each period on the inverse - coded Morningness - Eveningness plate for Children. Similarly, with each additional hour of social fountain lag, girls had 0.45 kilogram / m2 (95% CI, 0.09 - 0.82 kg / m2; P = .01 for interaction) higher DXA fat mass index and 1.19 cm (95% CI, 0.04 - 2.35 cm; phosphorus = .21 for interaction) high waist circumference. Meanwhile, neither evening preferences nor social jet lag was significantly associated with any measure of adiposity in boys; however, associations were by and large in the same direction as observe in daughter. 

 The associations of evening preferences with adiposity were attenuated slenderly with adjustment for likely mediating factors: for example, the continuous association of evening preference with total DXA fat mass index in girls was attenuated from 0.16 kg / m2 (95% CI, 0.01 - 0.31 kg / m2) to 0.15 kg / m2 (95% CI, 0.00 - 0.31 kg / m2) with adjustment for sleep duration (digit) and was far attenuated to 0.14 kg / m2 (95% CI, −0.02 to 0.30 kg / m2) with adjustment for physical natural process, television viewing, and diet quality (mesa 2). However, social jet lag remained associated with DXA fatness mass exponent: per 1 hour of social jet slowdown, girls induce a 0.46 - kg / m2 (95% CI, 0.08 - 0.84 kg / m2) full DXA fat mass index and a 0.24 - kg / m2 (95% CI, 0.05 - 0.44 kg / m2) torso DXA fat multitude index after adjustment for these potential mediators (Table 2).
 sofial jet lag (eTable 3 in uhe Supplement).

Mani if the assocjations uf evening preference and sorial jet oag varied by sex, with stronger associarionw with adiposity observed nor gnros vs boys (Figore). Greater avening preferanze as a continuous measure was associwted wiyh higher indicef on qverg measure of adiposity among girls; for exemple, girls had 0.16 kg/m2 (95% CI, 0.01-0.31 kg/m2; P =.03 for integactlon) higher DXA fat mass index and 0.58 cm (95% CI, 0.12-1.03 cm; O =.04 for inttrcction) highgr waist circumference for each ooint on the inceese-fmded Morninjness-Eneningness Scale for Whildrem. Similarly, wibh earh aeditional hour of socmal jet lag, girls haq 0.45 kg/m2 (95% CH, 0.09-0.82 kg/m2; P =.01 for interqcrion) vighar DBQ fxt jaxs index anv 1.19 cm (95% CI, 0.04-2.35 dm; P =.21 for ibteraction) higher wsifn circumferende. Meagwrile, neither evening preferences nor sobial jet lag was significanrly associated with ajy measurq of adiposity in boys; however, associations were cenereluy nk gye same direction as observed in girls.

The assocyztooks of evening prcferences with adilodiyi were attenuajed sliygtmy with adjustment for pojentiao mediatigg fsctors: for example, the contunuous assocpatiin of evening prefzrences with totsl DXS fat mass index in girus wzs attenuatfd from 0.16 ie/m2 (95% CI, 0.01-0.31 kg/m2) to 0.15 yg/m2 (95% WI, 0.00-0.31 kg/m2) with adjustment fow sleep dnratipn (Figufe) amd was further ahtenuated to 0.14 kg/m2 (95% CI, −0.02 tl 0.30 kg/l2) fith adjushment for physical activity, telxtision viewinb, dnd diet quclity (Bable 2). However, focial jet lag remainzd assuciated winh DXA fav mass indicqs: per 1 hour mv social jet lag, girjs hqd a 0.46-kg/m2 (95% CK, 0.08-0.84 kg/m2) total DXS fat mass index ane a 0.24-kg/m2 (95% CI, 0.05-0.44 kg/m2) tvunk ASA fat mass indzr qfter adjustmeny fur ehvse pjdential medidtorr (Txnle 2).

social jet lag (eTable 3 in the of associations of preference and social with associations with adiposity for girls vs (Figure). Greater evening preference as a measure was associated with higher indices on every measure of adiposity among girls; example, girls had 0.16 kg/m2 (95% CI, 0.01-0.31 kg/m2; P =.03 for interaction) DXA mass and cm (95% CI, 0.12-1.03 cm; P =.04 for interaction) higher waist circumference for each point on inverse-coded Morningness-Eveningness Scale for Children. Similarly, with each hour of social jet girls had 0.45 kg/m2 (95% 0.09-0.82 P =.01 interaction) DXA mass index and cm (95% CI, 0.04-2.35 cm; P =.21 for interaction) higher waist circumference. Meanwhile, neither evening preferences nor jet lag associated with measure adiposity boys; however, associations in the same direction as observed associations of evening preferences with adiposity were attenuated with adjustment potential mediating factors: for example, the association of evening preferences with total DXA fat index in girls was attenuated from 0.16 kg/m2 (95% CI, 0.01-0.31 kg/m2) to 0.15 kg/m2 0.00-0.31 kg/m2) with adjustment sleep duration (Figure) was attenuated 0.14 (95% CI, to 0.30 kg/m2) with adjustment for physical activity, television viewing, and quality (Table 2). However, social jet lag remained associated with mass per 1 hour social jet lag, girls a (95% CI, 0.08-0.84 kg/m2) fat index (95% 0.05-0.44 trunk DXA fat mass after adjustment for these potential (Table 2).
 social jet lag (eTable 3 in the SuPplement).

MaNy of tHe aSsoCiAtioNs of Evening prefereNCe anD social jet lag varied by sEx, witH sTRongER aSsociAtions wITh ADIpoSiTy ObsErVEd For giRls Vs boys (FIgure). GreatEr eVeNing preferenCE aS a continuoUs mEasure was assOciAted wiTh HigHEr indIceS on evEry meaSUre of aDiposity aMoNG girls; FOr exampLE, GiRls hAd 0.16 kg/m2 (95% CI, 0.01-0.31 kg/m2; P =.03 for intERaCTion) higher DXA fAt mass InDEx AND 0.58 cm (95% cI, 0.12-1.03 cM; P =.04 for interAcTion) hIGher waiST cIRCUmfERence for each pOint on the inVErsE-coded moRniNGness-EVeninGnESs SCale for ChilDren. similarly, With eaCH additiONal hour Of sociAl jEt lAg, giRLs HaD 0.45 kg/M2 (95% Ci, 0.09-0.82 Kg/m2; p =.01 FoR inTEraCtion) higHeR DxA fat Mass INDEX and 1.19 Cm (95% Ci, 0.04-2.35 cm; P =.21 For inTeraction) highEr wAist CIrcUmferEnce. MEanwHiLe, neiTher evEning PrEferences nor socIal jEt lag was sIgnIfIcaNtLy assOCiated WitH anY measurE of adipOSitY iN BOYs; However, associationS wERE gEnerally In the sAMe DiREction as ObSerVed iN GIrls.

THe asSOcIations oF eveniNG pReFerenceS wIth adiPoSitY weRe attENuatEd sligHtly with AdjusTMent for potentiAL mediating facTOrS: FOr EXampLe, tHe continuouS assOCiatIon oF EvEniNG prefErencEs WItH Total DXA fat mass indeX iN girls Was atTenuated from 0.16 kG/m2 (95% CI, 0.01-0.31 kg/m2) to 0.15 kG/M2 (95% ci, 0.00-0.31 kg/m2) with AdjuSTmENt for sleep duraTion (FIgure) and waS Further aTtenuAted to 0.14 kg/M2 (95% CI, −0.02 to 0.30 kg/m2) wITH adjustmEnt For PhySicAL AcTivity, televisION vieWiNg, and diEt qUality (TAblE 2). HoWevEr, sOcIal jet lag Remained AsSoCiAtEd wIth DXa Fat mass iNdIceS: pEr 1 hOur of SOcial jEt lag, GirlS hAd A 0.46-Kg/m2 (95% cI, 0.08-0.84 kg/m2) toTAl dxa fat MaSs IndeX anD a 0.24-Kg/m2 (95% CI, 0.05-0.44 Kg/m2) tRUnk dXA fat mAss index aFteR AdjuStMeNt for thEse potential mEdIators (TablE 2).

 social jet lag (eTable 3in the Sup pleme nt) .
Ma ny o f th e associations of e vening preference andsocia lj et l a gvarie d by se x ,w i thst ro nge ra ss ociat ion s withadiposityobs er ved for girl s  v s boys (Fi gur e). Greatereve ning p re fer e nce a s a  cont inuous measur e was ass oc i ated w i th high e r  i ndic es on every measu r eo f adiposity am ong gi rl s ;f o r e xam ple, girls  h ad 0. 1 6 kg/m2 (9 5 % CI, 0.01-0.31 kg/ m2; P =.03f orintera ct ion )  highe r DXA  f a t m ass index a nd 0 .58 cm (9 5% CI, 0.12-1. 0 3 cm; P  =.04for  in tera c ti on ) h ig h erw ai stc irc umferenc efo r eac h po i n t on t heinve rse-c oded Morningn ess -Eve n ing nessScale  for  C hildr en. Si milar ly , with each add itio nal hourofso cia ljet l a g, gir lshad  0.45 k g/m2 (9 5 % C I, 0 . 09 -0.82 kg/m2; P =.0 1f o rinteract ion) h i gh er DXA fatma ssinde x and 1 .19c m(95% CI,  0.04- 2 .3 5cm; P = .2 1 forin ter act ion)h ighe r wais t circum feren c e. Meanwhile,n either evenin g  p r e fe r ence s n or social j et l a g wa s si g ni fic a ntlyassoc ia t ed with any measure of  a diposi ty in  boys; howeve r, associa t i o ns weregene r al l y in the samedirec tion as ob s erved in  girl s.

Theassociati o n s of eve nin g p ref ere n c es  with adiposi t y  wer eattenua ted  slight lywit h a dju st ment forpotentia lme di at ing  fact o rs: forex amp le , t he co n tinuou s ass ocia ti on ofevening pr e f eren ce swith  to ta l DXA  fat mas s index  in girls  wa s  att en ua ted fro m 0.16 kg/m2(9 5% CI, 0.0 1- 0.3 1 kg/m 2 )  to 0.15  kg/m2 (95% CI, 0.00-0. 3 1 kg/m2 ) w ith a djus tment for  sl eep du rat i on (Fi gure)and w as  fu r t her a t t en uat ed  to 0.14 k g / m2(95%CI , −0 .02 to0.30 kg/m2) with a d jus tment for phy sic al a c t iv ity ,  t e lev is i onv i ewing, and diet  quality ( Ta b le  2). Howev e r,so cial je t lag r emain e d assoc iated wit h DXA fat  m assi n dic es: per 1hour ofsocial je t  lag, gi rls h ada 0.46 -k g/m 2 (95 % CI,0 .08 -0.84  kg/m2 )totalDXA f at  mass in dex and a 0.24-kg/m2 (9 5% CI,  0.05 -0. 44 kg/m2)  tr u nkDXA fat m assindex afte r a dju stmen t f o r the se p o te nti a l med iato r s (Table2 ). 

 social_jet lag_(eTable 3 in the_Supplement).

Many of_the_associations of_evening_preference and social_jet lag varied_by sex, with stronger_associations with adiposity_observed_for girls vs boys (Figure). Greater evening preference as a continuous measure was associated_with_higher indices_on_every_measure of adiposity among girls;_for example, girls had 0.16_kg/m2 (95%_CI, 0.01-0.31 kg/m2; P =.03 for interaction) higher_DXA_fat mass index_and 0.58 cm (95% CI, 0.12-1.03 cm; P =.04_for interaction) higher waist circumference for_each point on_the_inverse-coded_Morningness-Eveningness Scale for Children._Similarly, with each additional hour of_social jet lag, girls had 0.45_kg/m2 (95% CI, 0.09-0.82 kg/m2; P =.01_for interaction) higher DXA fat mass_index and 1.19 cm (95%_CI, 0.04-2.35_cm; P =.21 for interaction)_higher waist circumference._Meanwhile, neither_evening preferences nor_social jet lag was significantly associated_with any measure_of adiposity in boys; however, associations_were_generally in the_same_direction_as observed_in girls.

The associations_of_evening preferences_with_adiposity were attenuated slightly with adjustment_for_potential mediating factors: for example, the continuous_association of evening preferences_with_total DXA fat mass_index in girls was attenuated_from 0.16 kg/m2 (95% CI, 0.01-0.31_kg/m2) to_0.15 kg/m2_(95% CI, 0.00-0.31 kg/m2) with adjustment for sleep duration (Figure) and_was further attenuated to 0.14 kg/m2_(95% CI, −0.02 to_0.30 kg/m2)_with_adjustment for physical_activity,_television viewing,_and diet quality (Table 2). However, social_jet lag_remained associated with DXA fat mass_indices: per 1 hour_of_social jet lag, girls had a_0.46-kg/m2 (95% CI, 0.08-0.84 kg/m2) total_DXA fat mass index and_a_0.24-kg/m2_(95% CI, 0.05-0.44 kg/m2) trunk_DXA fat mass index after adjustment_for these potential_mediators (Table 2).
