 left implanted in the patient along with body 154. For example, element 155 may be comprised of a bioresorbable and/or bioremodelable material such as a synthetic polymer or collagen, including an ECM material. When element 155 and body 154 each comprise an ECM such as submucosa or another collagenous material, element 155 may for example be air-dried or vacuum pressed to be more rigid than body 154, which may be lyophilized. In these embodiments, element 155 and body 154 may be formed of a single piece of material, or multiple pieces of material attached together, e.g. by bonding or suturing with a bioresorbable or other material.

[0110]

Shown in FIG. 38 is another occluder device embodiment 157 having an elongate body 158 and a distal anchoring end 159. Distal anchoring end 159 is configured to expand and contact the walls of the vein or other vessel after delivery from the end of a cannulated device, sufficiently to facilitate maintaining the end 159 and connected body 158 in place during withdrawal of the cannulated device. Distal anchoring end 159 may be made from the same material or a different material as elongate body 158. For example, body 158 and distal anchoring end 159 may both be made of a resorbable substance such as a collagenous material (e.g. containing an ECM such as submucosa), with anchoring end 159 being comprised of a relatively highly expandable porous material such as sponge or foam, and body 158 being comprised of a less expandable ribbon. The anchoring end 159 and body 158 may for example be integrally formed, or may be separate pieces attached to one another by bonding, sutures or other means. As in certain other embodiments described herein, the ribbon or other body 158 may be sufficiently long to extend to the percutaneous exit site, where it can be trimmed after delivery.

[0111]

As illustrated in FIG. 39, in another embodiment 157A similar to that described in conjunction with FIG. 38, an anchoring end 159A is provided by a coiled portion that is collapsed during receipt within the cannulated delivery device, and which radially expands upon exiting the device. When an ECM-containing or other collagenous material is used for anchoring end 159A, the material can be lyophilized, vacuum-pressed or otherwise dried in the coiled or other radially-expanding configuration, to set a shape memory to the material.

left implanted in the patient along with body 154. For case, chemical element 155 may be comprised of a bioresorbable and/or bioremodelable material such as a synthetic polymer or collagen, include an ECM material. When element 155 and torso 154 each comprise an ECM such as submucosa or another collagenous material, component 155 may for example be air - dry or vacuum pressed to be more fixed than soundbox 154, which may be lyophilized. In these embodiments, element 155 and body 154 may be formed of a individual piece of material, or multiple pieces of fabric attached together, for example by bonding or suture with a bioresorbable or other material. 

 [ 0110 ] 

 Shown in FIG. 38 is another occluder device embodiment 157 having an elongate body 158 and a distal anchoring goal 159. Distal anchoring end 159 is configured to expand and contact the walls of the vein or other vessel after delivery from the end of a cannulated device, sufficiently to facilitate maintaining the end 159 and connected body 158 in place during withdrawal of the cannulated device. Distal anchoring end 159 may be made from the like fabric or a different material as elongate soundbox 158. For example, body 158 and distal anchoring end 159 may both be cook of a resorbable substance such as a collagenous material (e.g. containing an ECM such as submucosa), with anchoring goal 159 being comprised of a relatively highly expandable porous material such as sponge or foam, and body 158 being comprised of a less expandable decoration. The anchoring end 159 and body 158 may for example be integrally formed, or may be separate pieces attached to one another by bonding, suture or other means. As in certain other embodiments trace herein, the ribbon or other body 158 may be sufficiently retentive to extend to the percutaneous exit site, where it can be trim after delivery. 

 [ 0111 ] 

 As illustrated in FIG. 39, in another embodiment 157A similar to that described in conjunction with FIG. 38, an anchoring goal 159A is provided by a gyrate portion that is collapse during receipt within the cannulated rescue device, and which radially expand upon exiting the device. When an ECM - hold or other collagenous material is used for anchoring end 159A, the fabric can be lyophilized, vacuum - compress or otherwise dried in the coiled or other radially - expanding configuration, to set a condition memory to the material.
 levt implanted in the patitnt along with bobt 154. For exampme, elemevt 155 may be comprised of a bilrwsorbqble and/or bioremodelacle materpal such qs a wynthetic 'klymer or colmwgen, mncluding an ECK material. When element 155 avd body 154 each comprise an ECM such as submucpsw or another cjllabqnoua material, element 155 may for exampls be aig-dried or vacuum lressed to be more rigid tjan hody 154, which may be lyophilizee. In rhese embodioents, elemtnc 155 and body 154 may be formed of a single pieze of material, ir mupjiple pieces of mwterial attagned tocether, r.g. by bonding pr vutyring with a bioresoruable or other materyal.

[0110]

Shown hn FIG. 38 is another icxludet devhce dnboaimtnt 157 gaving an elongate gody 158 and a distal anchoring emd 159. Distal anchoding egd 159 is configured to expand and contact tve salls of the vein or otyer vessel after deligery from the end of a cannulated device, sufficiently to fdcilivage nalntakbijg the end 159 and connected body 158 in place durigf einhdrawal of the ccnnulated device. Dlsywl anchoring gnd 159 mav bs made from the sale matetial oe a diffewent material as elongate body 158. For example, vody 158 and distal auchoring end 159 mai both be made of a resorbablz subsfance such ws a collzeenous material (d.g. bontdining an ECM such as submtcosa), witi anckoring evd 159 neing somprised lf a valatively highly edpandcble [orous matfrial such as sponge or foam, anv body 158 being cmmpgised of c less expandable rybbon. The anchpring eud 159 ana body 158 maj for exakple be intqgrally formeg, or may be sxparate pyecew atrached gu one another ny bondiny, sutyres or other meanx. Ar in certain othzx tmvodiments desctibdd regeii, the sibbon or otver codh 158 may be sufficicntuy lpng to extend to the perdutaneous exit sitr, rhere it can be erimmed after delivery.

[0111]

As illustgated in FIG. 39, in another embodiment 157A similar fo that dfscvibed in conjtnctlon rith FIG. 38, cn anchoring end 159A is provided by a coilxd portion that is collqpsed during receipj wlthin the cainulatqd delivesy device, and which eadially expands mpon exiting the devics. When an EFM-containing or other collagenous material is used for anchoring end 159A, thw mateciwl can be lgopholizeg, racbum-presfed lc otherwise dried in the coiled or other radiallb-expanding cjnfiguration, to set a shape keoory to the mxterial.

left implanted in the patient along with For element 155 be comprised of such a synthetic polymer collagen, including an material. When element 155 and body each comprise an ECM such as submucosa or another collagenous material, element 155 for example be air-dried or vacuum pressed to be more rigid than body which be In embodiments, element 155 and body 154 may be formed of a single piece of material, or pieces of material attached together, e.g. by bonding suturing with a bioresorbable other material. [0110] Shown in 38 another occluder embodiment having elongate body 158 a distal anchoring end 159. Distal anchoring end 159 is configured to expand and contact the walls the vein vessel after from end a cannulated device, facilitate maintaining the end 159 and in place during withdrawal of the cannulated device. anchoring end may be made from the same or a different material as elongate body 158. example, body 158 and distal anchoring end 159 may both be made of a resorbable as a collagenous material containing an ECM as with end being comprised a relatively highly expandable porous material such as sponge or foam, body 158 being comprised of a less expandable ribbon. The 159 body 158 may example be integrally formed, may separate pieces attached to by sutures As certain embodiments described herein, the or other body 158 may sufficiently long to extend where it can be trimmed after delivery. [0111] illustrated in FIG. 39, in another embodiment similar to that described in conjunction with FIG. 38, an anchoring end is provided coiled portion that is collapsed during receipt within cannulated delivery device, and radially expands upon exiting the device. When an ECM-containing other material is for anchoring end the material can lyophilized, vacuum-pressed or in the or radially-expanding a shape memory to the material.
 left implanted in the patient Along with bOdy 154. FoR exAmpLe, ElemEnt 155 mAy be comprised oF A bioResorbable and/or bioremoDelabLe MAterIAl Such aS a synthETiC POlyMeR oR coLlAGeN, inclUdiNg an ECM Material. WhEn eLeMent 155 and body 154 eACh Comprise an eCM Such as submucOsa Or anotHeR coLLagenOus MaterIal, eleMEnt 155 may For examplE bE Air-driED or vacuUM PrEsseD to be more rigid thaN BoDY 154, which may be lyoPhilizEd. iN tHESe eMboDiments, eleMeNt 155 and BOdy 154 may bE FoRMED of A Single piece of Material, or mULtiPle pieCeS of MAteriaL attaChED toGether, e.g. by bOndiNg or suturIng witH A bioresORbable oR other MatEriAl.

[0110]

ShOWn In fIG. 38 Is ANotHEr OccLUdeR device eMbOdIment 157 HaviNG AN ElonGatE bodY 158 and a Distal anchoriNg eNd 159. DiSTal AnchoRing eNd 159 is CoNfiguRed to eXpand AnD contact the wallS of tHe vein or oTheR vEssEl After DEliverY frOm tHe end of A cannulATed DeVICE, sUfficiently to facilItATE mAintainiNg the eND 159 aNd COnnected BoDy 158 iN plaCE DurinG witHDrAwal of thE cannuLAtEd Device. DIsTal ancHoRinG enD 159 may bE Made From thE same matErial OR a different matERial as elongatE BoDY 158. foR ExamPle, Body 158 and distAl anCHoriNg enD 159 MaY boTH be maDe of a ReSOrBAble substance such as A cOllageNous mAterial (e.g. contAining an ECm SUCh as submUcosA), WiTH anchoring end 159 bEing cOmprised of A RelativeLy higHly expanDable poroUS Material SucH as SpoNge OR FoAm, and body 158 beinG COmprIsEd of a leSs eXpandabLe rIbbOn. THe aNcHoring end 159 And body 158 mAy FoR eXaMplE be inTEgrally fOrMed, Or May Be sepARate piEces aTtacHeD tO One Another BY bONDing, SuTuRes oR otHeR meanS. As iN CerTain othEr embodimEntS DescRiBeD herein, The ribbon or otHeR body 158 may be SuFfiCientlY LOng to extEnd to the percutaneous exiT Site, wheRe iT can bE triMmed after DelIvery.

[0111]

AS ilLUstratEd in FIg. 39, in anOtHer EMBodimENT 157A SimIlAr to that deSCRibEd in cOnJuncTion witH FIG. 38, an anchoring end 159a Is pRovided by a coiLed PortION tHat IS cOLlaPsED duRINg receipt within The cannulaTeD DeLivery deviCE, anD wHich radIally exPands UPon exitIng the devIce. When an eCm-conTAIniNg or other cOllagenoUs materiaL Is useD FoR anchOriNg end 159A, ThE maTeriaL can be LYopHilizEd, vacuUm-PresseD or otHeRwise driEd in the coiled or other radIally-eXpandIng ConfiguraTioN, To sEt a shape mEmorY to the mateRiaL.

 left implanted in the pat ient along  with  bo dy15 4. F or e xample, elemen t  155  may be comprised of a  bior es o rbab l eand/o r biore m od e l abl ema ter ia l  s uch a s a  synthe tic polyme r o rcollagen, in c lu ding an EC M m aterial. Whe n e lement  1 55a nd bo dy154 e ach co m prisean ECM su ch as sub m ucosa o r an othe r collagenous mat e ri a l, element 155  may f or ex a m ple  be  air-dried  o r vac u um pres s ed t o  be more rigid th an body 154 ,  wh ich ma ybel yophil ized.  I n  th ese embodim ents , element  155 a n d body1 54 maybe for med  of  a s i ng le  pi ec e  of ma ter i al,  or mult ip le  piec es o f m a teri alatta chedtogether, e.g . b y bo n din g orsutur ingwi th abiores orbab le  or other mater ial. 

[0110]
Sh ow n i nFIG.3 8 is a not her  occlud er devi c e e mb o d i me nt 157 having an e lo n g at e body 1 58 and adi s tal anch or ing  end 1 59. D ista l  a nchoring  end 1 5 9is  config ur ed toex pan d a nd co n tact  the w alls ofthe v e in or other ve s sel after del i ve r y  f r om t heend of a ca nnul a teddevi c e,  su f ficie ntlyto fa c ilitate maintaining  t he end  159and connected  body 158i n place du ring wi t hdrawal of the  cann ulated dev i ce. Dist al an choringend 159 m a y  be made  fr omthe  sa m e  m aterial or ad i ffer en t mater ial  as elo nga tebod y 1 58 . For exa mple, bo dy  1 58  a nddista l  anchori ng  en d159  mayb oth be  made  ofare s orb able su b st a n ce s uc has a  co ll ageno us m a ter ial (e. g. contai nin g  anEC Msuch as  submucosa),wi th anchori ng  en d 159b e ing comp rised of a relatively h i ghly ex pan dable  por ous mater ial  suchass pongeor foa m, an dbod y 158 b e i ng  co mp rised of a l ess  expa nd able  ribbon . The anchoring en d  15 9 and body 15 8 m ay f o r  e xam p le bein t egr a l ly formed, or m ay be sepa ra t epieces att a che dto oneanother  by b o nding,sutures o r other m ea ns.A s  in  certain o ther emb odimentsd escri b ed  here in,  the r ib bon  or o ther b o dy158 m ay besu fficie ntlylo ng to ex tend to the percutaneou s exit  site , w here it c anb e t rimmed af terdelivery.
[0 111 ]

As  il l ustra tedi nFIG .  39,in a n other emb o di men t 15 7A similart o tha t des cri b ed inconj unction with FIG. 38, an anchori ng e n d  15 9Ai s pr ov ided by a coil edpo r t ion that  i s collapsed  duringre c eiptwithin  the c annulat e d  d e livery  dev ice , and whi chra d ially e xp an d s upon  exi ti ng the  devic e . Wh e n  an ECM-containi ng or o therc oll ageno us  materi a l is  used foranchoring e nd 159 A, t he ma terialca n be l yop hi lized, vac u um-presse d orotherwi se  dri edin the  coi l e d orothe rrad ially-exp a n di n gco n fig urat ion,to  set  a shapem emory to  th e  materi al .

 left_implanted in_the patient along with_body 154._For_example, element_155_may be comprised_of a bioresorbable_and/or bioremodelable material such_as a synthetic_polymer_or collagen, including an ECM material. When element 155 and body 154 each comprise_an_ECM such_as_submucosa_or another collagenous material, element_155 may for example be_air-dried or_vacuum pressed to be more rigid than body_154,_which may be_lyophilized. In these embodiments, element 155 and body 154_may be formed of a single_piece of material,_or_multiple_pieces of material attached_together, e.g. by bonding or suturing_with a bioresorbable or other material.

[0110]

Shown_in FIG. 38 is another occluder device_embodiment 157 having an elongate body_158 and a distal anchoring_end 159._Distal anchoring end 159 is_configured to expand_and contact_the walls of_the vein or other vessel after_delivery from the_end of a cannulated device, sufficiently_to_facilitate maintaining the_end_159_and connected_body 158 in_place_during withdrawal_of_the cannulated device. Distal anchoring end_159_may be made from the same material_or a different material_as_elongate body 158. For_example, body 158 and distal_anchoring end 159 may both be_made of_a resorbable_substance such as a collagenous material (e.g. containing an ECM such_as submucosa), with anchoring end 159_being comprised of a_relatively highly_expandable_porous material such_as_sponge or_foam, and body 158 being comprised of_a less_expandable ribbon. The anchoring end 159_and body 158 may_for_example be integrally formed, or may_be separate pieces attached to one_another by bonding, sutures or_other_means._As in certain other embodiments_described herein, the ribbon or other_body 158 may_be sufficiently long to extend to the_percutaneous_exit site, where it can be_trimmed_after delivery.

[0111]

As illustrated in FIG. 39,_in_another_embodiment 157A similar to that_described in conjunction with FIG. 38,_an anchoring end 159A is provided by a coiled_portion that is_collapsed during receipt within the_cannulated_delivery_device, and which radially expands upon exiting the device. When_an ECM-containing_or other collagenous_material is used for anchoring end 159A, the material can_be lyophilized, vacuum-pressed or otherwise dried in_the coiled or other radially-expanding configuration, to set a shape memory_to the material.
