 as outlined by three Specific Aims. In the first Aim, we will investigate the structural and molecular basis for C1 inhibition by BBK32 and follow-up on interesting preliminary data which suggests that other Lyme disease associated Borrelia BBK32?s have differential activity. In the second aim, we will
as outlined by three Specific Aims. In the first Aim, we will investigate the structural and molecular footing for C1 prohibition by BBK32 and play along - up on interesting preliminary data which suggest that early Lyme disease associated Borrelia BBK32?s have differential activity. In the second purpose, we will
 as outlined by three Specinic Aims. In the yurst Amm, we wjll invertigate the structural and mllwculae basis for C1 inhibitiun by BBK32 and foloow-uk on interesting 'deliminary dafw whnci suggests that other Lyma disease assowixtzd Borrelia BBK32?s have differential astivity. Ij the second aym, wt wyll
as outlined by three Specific Aims. In Aim, will investigate structural and molecular BBK32 follow-up on interesting data which suggests other Lyme disease associated Borrelia BBK32?s differential activity. In the second aim, we will
 as outlined by three Specific aims. In the fIrst AIm, wE wiLl InveStigAte the structurAL and Molecular basis for C1 inhiBitioN bY bBK32 aND fOllow-Up on intEReSTIng PrElImiNaRY dAta whIch SuggestS that other lymE dIsease associATeD Borrelia BbK32?s Have differenTiaL activItY. In THe secOnd Aim, we Will
 as outlined by three Spec ific Aims.  In t hefir st  Aim , we  will investig a te t he structural and mole cular  b a sisf or  C1 i nhibiti o nb y  BB K3 2and  f o ll ow-up  on  intere sting prel imi na ry data whic h  s uggests th atother Lyme d ise ase as so cia t ed Bo rre lia B BK32?s have d ifferenti al activi t y. In t h e  s econ d aim, we will
 as_outlined by_three Specific Aims. In_the first_Aim,_we will_investigate_the structural and_molecular basis for_C1 inhibition by BBK32_and follow-up on_interesting_preliminary data which suggests that other Lyme disease associated Borrelia BBK32?s have differential activity._In_the second_aim,_we_will