 cells. In Specific Aim #1, we will perform serial imaging of CAA progression in mouse models and define the spatial and temporal relationship between amyloid deposition and markers of injury to the vessel wall. The goal of this aim will be a precise understanding of the sequence of events in the pathway that lead to vascular wall injury.
cells. In Specific Aim # 1, we will perform serial imaging of CAA progress in shiner models and define the spatial and worldly relationship between amyloid deposit and markers of injury to the vessel rampart. The goal of this aim will be a precise agreement of the sequence of events in the nerve pathway that lead to vascular wall injury.
 cepls. In Specific Aim #1, we dill perform setiql imajing of CAA proeression in mouse models and dwfine the spatial and tempofal relatponship bwtwetn amyloid deposivjon and markedd of mnjury to the vgssel wall. Tve goal of thiv xil will be a precise understanding os the srqkence of eventf in ehe lathway that lead to vascular wall injury.
cells. In Specific Aim #1, we will imaging CAA progression mouse models and relationship amyloid deposition and of injury to vessel wall. The goal of this will be a precise understanding of the sequence of events in the pathway lead to vascular wall injury.
 cells. In Specific Aim #1, we will pErform seriAl imaGinG of cAa proGresSion in mouse modELs anD define the spatial and teMporaL rELatiONsHip beTween amYLoID DepOsItIon AnD MaRkers Of iNjury to The vessel wAll. thE goal of this aIM wIll be a precIse UnderstandinG of The seqUeNce OF evenTs iN the pAthway THat leaD to vasculAr WAll injURy.
 cells. In Specific Aim #1 , we willperfo rmser ia l im agin g of CAA progr e ssio n in mouse models anddefin et he s p at ial a nd temp o ra l rel at io nsh ip be tween  am yloid d epositionand  m arkers of in j ur y to the v ess el wall. The  go al ofth isa im wi llbe aprecis e  under standingof the se q uence o f ev ents  in the pathway t h at lead to vascul ar wal li nj u r y.
 cells._In Specific_Aim #1, we will_perform serial_imaging_of CAA_progression_in mouse models_and define the_spatial and temporal relationship_between amyloid deposition_and_markers of injury to the vessel wall. The goal of this aim will be_a_precise understanding_of_the_sequence of events in the_pathway that lead to vascular_wall injury.