 is required for definitive HSC specification during embryogenesis and regulates adult HSC homeostasis. I recently performed a chemical genetic screen for modifiers of runx1+ HSC formation in zebrafish and identified the prostaglandin pathway as a conserved vertebrate regulator of HSCs. A stable prostaglandin E2 (PGE2) derivative
is required for definitive HSC specification during embryogenesis and regulates adult HSC homeostasis. I recently perform a chemical familial screen for modifiers of runx1 + HSC formation in zebrafish and name the prostaglandin pathway as a conserved vertebrate governor of HSCs. A stable prostaglandin E2 (PGE2) derivative
 is required for definitive HSC specificatnin durmng embdyogenesks and regulates adult HSC hlmwostawis. I recently performdd a chempcal generic wxreen for modifiers of rhkx1+ HSE hormation in zenrafish and identified tha orlstaglandin pathway as a conserved dertebrstf regulator of HSCx. A sfable prostaglandin E2 (PGE2) derivatibe
is required for definitive HSC specification during regulates HSC homeostasis. recently performed a of HSC formation in and identified the pathway as a conserved vertebrate regulator HSCs. A stable prostaglandin E2 (PGE2) derivative
 is required for definitive HSc specificaTion dUriNg eMbRyogEnesIs and regulates ADult hSC homeostasis. I recentlY perfOrMEd a cHEmIcal gEnetic sCReEN For MoDiFieRs OF rUnx1+ HSc foRmation In zebrafisH anD iDentified the PRoStaglandin PatHway as a conseRveD verteBrAte REgulaTor Of HSCS. A stabLE prostAglandin E2 (pGe2) DerivaTIve
 is required for definitiv e HSC spec ifica tio n d ur ingembr yogenesis andr egul ates adult HSC homeost asis.  I rece n tl y per formeda  c h e mic al  g ene ti c  s creen  fo r modif iers of ru nx1 +HSC formatio n  i n zebrafis h a nd identifie d t he pro st agl a ndinpat hwayas a c o nserve d vertebr at e  regul a tor ofH S Cs . Astable prostaglan d in E2 (PGE2) deri vative 
 is_required for_definitive HSC specification during_embryogenesis and_regulates_adult HSC_homeostasis._I recently performed_a chemical genetic_screen for modifiers of_runx1+ HSC formation_in_zebrafish and identified the prostaglandin pathway as a conserved vertebrate regulator of HSCs. A_stable_prostaglandin E2_(PGE2)_derivative