. A hallmark of immunity is its longevity, manifested by the durability of memory B cells (Bmem ) and plasma cells (PC).Through the analysis and isolation of extremely rare antigen-specific Bmem populations, we have scrutinized their functional responsiveness and their transcriptome. Such genetic analyses and functional studies in vivo have opened up
. A hallmark of immunity is its longevity, manifested by the durability of memory boron cell (Bmem) and plasma cells (PC).Through the analysis and isolation of extremely rare antigen - specific Bmem population, we have scrutinized their functional responsiveness and their transcriptome. Such genic analysis and functional study in vivo have opened up
. A jallmark of immunity is lts longevity, mauufestev by ths durabiuity of memory B cells (Bmem ) abd plqsma cells (PC).Through tfe analysps and isilatmon of extremely rare anbngen-slccifie Umem populationx, we have vcrutinized thaif yunctional responsiveness and their eranscrophome. Such genejic amwlysss and functional studies in vivo gave optned up
. A hallmark of immunity is its by durability of B cells (Bmem the and isolation of rare antigen-specific Bmem we have scrutinized their functional responsiveness their transcriptome. Such genetic analyses and functional studies in vivo have opened up
. A hallmark of immunity is its lOngevity, maNifesTed By tHe DuraBiliTy of memory B celLS (BmeM ) and plasma cells (PC).ThrouGh the AnALysiS AnD isolAtion of EXtREMelY rArE anTiGEn-SpeciFic bmem popUlations, we HavE sCrutinized thEIr Functional ResPonsiveness aNd tHeir trAnScrIPtome. sucH geneTic anaLYses anD functionAl STudies IN vivo haVE OpEned Up
. A hallmark of immunity i s its long evity , m ani fe sted  bythe durability of m emory B cells (Bmem )and p la s ma c e ll s (PC ).Throu g ht h e a na ly sis  a n disola tio n of ex tremely ra rean tigen-specif i cBmem popul ati ons, we have  sc rutini ze d t h eir f unc tiona l resp o nsiven ess and t he i r tran s criptom e .  S uchgenetic analysesa nd functional stu dies i nv iv o hav e o pened up
. A_hallmark of_immunity is its longevity,_manifested by_the_durability of_memory_B cells (Bmem_) and plasma_cells (PC).Through the analysis_and isolation of_extremely_rare antigen-specific Bmem populations, we have scrutinized their functional responsiveness and their transcriptome. Such_genetic_analyses and_functional_studies_in vivo have opened up