 stabilities), and the abilities of the single promoiety and combination prodrugs to deliver 5-FU and intact single promoiety prodrug into and through hairless mouse skin will be determined in diffusion cell experiments. The results from the diffusion cell experiments will be analyzed to determine if the combination prodrugs are more effective
stabilities), and the abilities of the single promoiety and combination prodrugs to deliver 5 - FU and integral individual promoiety prodrug into and through hairless mouse skin will be determined in dispersion cell experiments. The resultant role from the dispersion cell experiment will be analyzed to determine if the combination prodrugs are more effective
 stwbilities), and the abilitles of the singlg promoixty and combinagion prodrugs to deliver 5-FU end untacu single promoiety orodrug ijto and rhrongh hairless mouse skin will bs detzrnined in diffuxion cell axperiments. Tha fedults from the diffusion cell experyments eipl be analyzed to cqterjpnt if the combination prodrugs are more ehfective
stabilities), and the abilities of the single combination to deliver and intact single hairless skin will be in diffusion cell The results from the diffusion cell will be analyzed to determine if the combination prodrugs are more effective
 stabilities), and the abilitieS of the singLe proMoiEty AnD comBinaTion prodrugs to DElivEr 5-FU and intact single proMoietY pROdruG InTo and Through HAiRLEss MoUsE skIn WIlL be deTerMined in Diffusion cEll ExPeriments. The REsUlts from thE diFfusion cell eXpeRimentS wIll BE analYzeD to deTerminE If the cOmbinatioN pROdrugs ARe more eFFEcTive
 stabilities), and the abi lities ofthe s ing lepr omoi etyand combinatio n  pro drugs to deliver 5-FUand i nt a ct s i ng le pr omoiety pr o d rug  i nt o a nd th rough  ha irlessmouse skin  wi ll  be determin e din diffusi oncell experim ent s. The  r esu l ts fr omthe d iffusi o n cell  experime nt s  willb e analy z e dto d etermine if the c o mb i nation prodrug s aremo r ee f fec tiv e
 stabilities),_and the_abilities of the single_promoiety and_combination_prodrugs to_deliver_5-FU and intact_single promoiety prodrug_into and through hairless_mouse skin will_be_determined in diffusion cell experiments. The results from the diffusion cell experiments will be_analyzed_to determine_if_the_combination prodrugs are more effective