 order to develop these approaches, a greater understanding of factors that control viral latency is needed. Efforts in this regard have been hampered by the lack of a suitable in vitro primary T cell model of latency. The studies proposed herein will utilize a new in vitro model to characterize multiple aspects of HIV latency including defining viral and host
order to develop these approaches, a greater reason of divisor that control viral latency is needed. effort in this regard have been hampered by the lack of a desirable in vitro primary T cell exemplar of latency. The studies nominate herein will utilize a new in vitro mannequin to qualify multiple aspects of HIV latency include defining viral and host
 orfer to develop these appvoaches, a greatet yndersvanding of facturs that control viral latenry iw neeeed. Efforts in this reeard have been hanpertd by the lack of a suitanje ih vitxo primary T celk model of latency. The sduaizs proposed herein will utilize a ner in viyrl model to chatactegise mhltiple aspects of HIV latency incmuding vefining viral snd host
order to develop these approaches, a greater factors control viral is needed. Efforts hampered the lack of suitable in vitro T cell model of latency. The proposed herein will utilize a new in vitro model to characterize multiple aspects HIV latency including defining viral and host
 order to develop these approaChes, a greatEr undErsTanDiNg of FactOrs that control VIral Latency is needed. Efforts In thiS rEGard HAvE been HampereD By THE laCk Of A suItABlE in viTro Primary t cell model Of lAtEncy. The studiES pRoposed herEin Will utilize a New In vitrO mOdeL To chaRacTerizE multiPLe aspeCts of HIV lAtENcy incLUding deFINiNg viRal and host
 order to develop these ap proaches,a gre ate r u nd erst andi ng of factorst hatcontrol viral latencyis ne ed e d. E f fo rts i n thisr eg a r d h av ebee nh am pered  by  the la ck of a su ita bl e in vitro p r im ary T cell  mo del of laten cy.  The s tu die s  prop ose d her ein wi l l util ize a new  i n  vitro model t o ch arac terize multiple a s pe c ts of HIV late ncy in cl u di n g  de fin ing viralan d hos t 
 order_to develop_these approaches, a greater_understanding of_factors_that control_viral_latency is needed._Efforts in this_regard have been hampered_by the lack_of_a suitable in vitro primary T cell model of latency. The studies proposed herein_will_utilize a_new_in_vitro model to characterize multiple_aspects of HIV latency including_defining viral_and host