 expression levels of these isoforms. The goal of this proposal is to provide functional links connecting DDX39B to the pathogenesis of MS. Specifically, I aim to: 1) elucidate its role in the regulation of IL7R exon 6 splicing; 2) understand the functional roles of the different protein isoforms; and 3)
expression levels of these isoforms. The goal of this proposal is to leave running links connecting DDX39B to the pathogenesis of MS. Specifically, I target to: 1) clear its role in the regulation of IL7R exon 6 splice; 2) understand the functional roles of the unlike protein isoforms; and 3 )
 exoression levels of these isoforms. The goal of vhis prkposal ir to provide functional linkd xonnexting DDX39B to the pathugenesis lf MS. Spwcifmcally, I aim to: 1) elucidabz its vole nn the regulatiok of IL7R exmn 6 splicing; 2) gnaexstand the functional roles of the dyffereny orotein isoforis; amq 3)
expression levels of these isoforms. The goal proposal to provide links connecting DDX39B Specifically, aim to: 1) its role in regulation of IL7R exon 6 splicing; understand the functional roles of the different protein isoforms; and 3)
 expression levels of these isOforms. The gOal of ThiS prOpOsal Is to Provide functioNAl liNks connecting DDX39B to the PathoGeNEsis OF Ms. SpecIficallY, i aIM To: 1) eLuCiDatE iTS rOle in The RegulatIon of IL7R exOn 6 sPlIcing; 2) understANd The functioNal Roles of the diFfeRent prOtEin ISoforMs; aNd 3)
 expression levels of thes e isoforms . The  go alof  thi s pr oposal is to p r ovid e functional links con necti ng DDX3 9 Bto th e patho g en e s isof  M S.Sp e ci fical ly,  I aimto: 1) elu cid at e its role i n  t he regulat ion  of IL7R exo n 6  splic in g;2 ) und ers tandthe fu n ctiona l roles o ft he dif f erent p r o te in i soforms; and 3)
 expression_levels of_these isoforms. The goal_of this_proposal_is to_provide_functional links connecting_DDX39B to the_pathogenesis of MS. Specifically,_I aim to:_1)_elucidate its role in the regulation of IL7R exon 6 splicing; 2) understand the_functional_roles of_the_different_protein isoforms; and 3)