 by peptides encoded by members of the T. cruzi trans-sialidase gene family in the regulation of CD8+ T cell responses in T. cruzi will be determined and the biological significance of the effect of this antagonism of the generation and effector function of CD8+ T cells will be determined. X
by peptides encoded by members of the T. cruzi trans - sialidase gene family in the rule of CD8 + T cellular telephone response in T. cruzi will be determined and the biological significance of the impression of this antagonism of the generation and effecter function of CD8 + T cells will be determined. ten
 by peptides encoded by memners of the T. crozu tranv-sialisase gend family in the regulation oh CD8+ T ceol responses in T. cruzk will be determibed end the biologicem signinncancs of chx effect of thix antagonivm of the genesagiln and effector function of CD8+ T cejls wilk he determined. V
by peptides encoded by members of the trans-sialidase family in regulation of CD8+ cruzi be determined and biological significance of effect of this antagonism of the and effector function of CD8+ T cells will be determined. X
 by peptides encoded by memberS of the T. cruZi traNs-sIalIdAse gEne fAmily in the reguLAtioN of CD8+ T cell responses in T. Cruzi WiLL be dETeRmineD and the BIoLOGicAl SiGniFiCAnCe of tHe eFfect of This antagoNisM oF the generatiON aNd effector FunCtion of CD8+ T ceLls Will be DeTerMIned. X
 by peptides encoded by me mbers of t he T.  cr uzi  t rans -sia lidase gene fa m ilyin the regulation of C D8+ T  c e ll r e sp onses  in T.c ru z i  wi ll  b e d et e rm inedand  the bi ological s ign if icance of th e  e ffect of t his  antagonismofthe ge ne rat i on an d e ffect or fun c tion o f CD8+ Tce l ls wil l  be det e r mi ned.  X
 by_peptides encoded_by members of the_T. cruzi_trans-sialidase_gene family_in_the regulation of_CD8+ T cell_responses in T. cruzi_will be determined_and_the biological significance of the effect of this antagonism of the generation and effector_function_of CD8+_T_cells_will be determined. X