 hypothesis by focusing on two aims. Aim 1: Determine effects of cocaine-induced down-regulation of anti-HIV cellular miRNAs on HIV-1 replication. Aim 2: Examine whether cocaine-induced down-regulation of anti-HIV cellular miRNAs activate latently infected HIV-1. PUBLIC HEALTH RELEVANCE:
hypothesis by focusing on two aims. Aim 1: Determine effect of cocaine - induce down - regulation of anti - HIV cellular miRNAs on HIV-1 replication. Aim 2: probe whether cocaine - induced down - regulation of anti - HIV cellular miRNAs trip latently infected HIV-1. PUBLIC HEALTH RELEVANCE:
 hyoothesis by focusing on uwo aims. Aim 1: Detgrnine ehfects kf cocaive-induced down-regulation of enti-YIV ctjlular miRNAs on HKV-1 replicwtion. Ain 2: Eeamine whether cocaine-induced slwn-rzgnlation of anti-MIV cellulas miRNAs activdtd patently infected HIV-1. PUBLIC HEALTH RELEVAMCF:
hypothesis by focusing on two aims. Aim effects cocaine-induced down-regulation anti-HIV cellular miRNAs Examine cocaine-induced down-regulation of cellular miRNAs activate infected HIV-1. PUBLIC HEALTH RELEVANCE:
 hypothesis by focusing on two Aims. Aim 1: DetErminE efFecTs Of coCainE-induced down-reGUlatIon of anti-HIV cellular mirNAs oN Hiv-1 repLIcAtion. aim 2: ExamINe WHEthEr CoCaiNe-INdUced dOwn-RegulatIon of anti-HiV cElLular miRNAs aCTiVate latentLy iNfected HIV-1. PUbLIc HEALTh ReLEvaNCE:
 hypothesis by focusing on  two aims.  Aim1:Det er mine  eff ects of cocain e -ind uced down-regulation o f ant i- H IV c e ll ularmiRNAso nH I V-1  r ep lic at i on . Aim  2:  Examin e whethercoc ai ne-induced d o wn -regulatio n o f anti-HIV c ell ular m iR NAs activ ate  late ntly i n fected  HIV-1. P UB L IC HEA L TH RELE V A NC E:
 hypothesis_by focusing_on two aims. Aim_1: Determine_effects_of cocaine-induced_down-regulation_of anti-HIV cellular_miRNAs on HIV-1_replication. Aim 2: Examine_whether cocaine-induced down-regulation_of_anti-HIV cellular miRNAs activate latently infected HIV-1. PUBLIC HEALTH RELEVANCE: