 research is directed at epithelial differentiation in normal and pathologic states. This grant focuses on the roles of vitamins and hormones, as exemplified by retinoids and thyroid hormones, in the control of keratin synthesis and in the process of keratinization. For decades, clinicians have recognized that thyroid hormones and vitamin A had profound effects upon normal and
research is directed at epithelial differentiation in normal and pathologic state. This concession focuses on the roles of vitamin and hormones, as exemplify by retinoids and thyroid hormones, in the control condition of keratin synthesis and in the process of keratinization. For decade, clinicians have recognized that thyroid gland hormones and vitamin A had profound effect upon normal and
 redearch is directed at eplthelial differeuriatioi in nodmal and pathologic states. This granv foxuses on the roles of vitamkns and hlrmones, qs eeemplified by revjnoids and thgvoid kocmones, in the cpntrol of neratin synthevir cnd in the process of keratinization. For devafes, clinicians havt rqcoghpztd that thyroid hormones and vitajin A hed profound effrcts upon normal and
research is directed at epithelial differentiation in pathologic This grant on the roles exemplified retinoids and thyroid in the control keratin synthesis and in the process keratinization. For decades, clinicians have recognized that thyroid hormones and vitamin A had effects upon normal and
 research is directed at epithElial diffeRentiAtiOn iN nOrmaL and Pathologic statES. ThiS grant focuses on the roleS of viTaMIns aND hOrmonEs, as exeMPlIFIed By ReTinOiDS aNd thyRoiD hormonEs, in the conTroL oF keratin syntHEsIs and in the ProCess of keratiNizAtion. FOr DecADes, clIniCians Have reCOgnizeD that thyrOiD HormonES and vitAMIn a had Profound effects upON nORmal and
 research is directed at e pithelialdiffe ren tia ti on i n no rmal and patho l ogic  states. This grant fo cuses  o n  the ro les o f vitam i ns a ndho rm one s, as  exem pli fied by  retinoids  an dthyroid horm o ne s, in thecon trol of kera tin  synth es isa nd in  th e pro cess o f  kerat inization .F or dec a des, cl i n ic ians  have recognizedt ha t  thyroid hormo nes an dv it a m inA h ad profoun deffec t s uponn or m a l  an d 
 research_is directed_at epithelial differentiation in_normal and_pathologic_states. This_grant_focuses on the_roles of vitamins_and hormones, as exemplified_by retinoids and_thyroid_hormones, in the control of keratin synthesis and in the process of keratinization. For_decades,_clinicians have_recognized_that_thyroid hormones and vitamin A_had profound effects upon normal_and