 1kHz bandwidth. A critical and innovative aspect of this work is the integration of the PR force clamp with patch-clamp electrophysiology for synchronous force-displacement- physiological recordings. This technology will enable the first direct measurement of dynamic changes in tissue stiffness that may occur during mechano-electrical transduction and give
1kHz bandwidth. A critical and innovative aspect of this work is the integration of the public relations power clamp with patch - clamp electrophysiology for synchronous force - displacement- physiological recording. This technology will enable the first lineal measurement of dynamic changes in tissue stiffness that may happen during mechano - electric transduction and give
 1kHx bandwidth. A critical akd innovative askext of vhis wodk is thd integration of the PR forcx clqmp wuth patch-clamp electroohysiologj for synxhroious force-displarsment- pmvsiolknical cecordings. This technologf will enable dhd yirst direct measurement of dynamic shanges ij tissue stiffgess ehat may occur during mechano-electricam transvuction and givr
1kHz bandwidth. A critical and innovative aspect work the integration the PR force synchronous physiological recordings. This will enable the direct measurement of dynamic changes in stiffness that may occur during mechano-electrical transduction and give
 1kHz bandwidth. A critical and iNnovative aSpect Of tHis WoRk is The iNtegration of thE pR foRce clamp with patch-clamp ElectRoPHysiOLoGy for SynchroNOuS FOrcE-dIsPlaCeMEnT- physIolOgical rEcordings. THis TeChnology will ENaBle the firsT diRect measuremEnt Of dynaMiC chANges iN tiSsue sTiffneSS that mAy occur duRiNG mechaNO-electrICAl TranSduction and give
 1kHz bandwidth. A critica l and inno vativ e a spe ct  ofthis  work is the i n tegr ation of the PR forceclamp  w i th p a tc h-cla mp elec t ro p h ysi ol og y f or sy nchro nou s force -displacem ent -physiologica l  r ecordings.  Th is technolog y w ill en ab let he fi rst  dire ct mea s uremen t of dyna mi c  chang e s in ti s s ue  sti ffness that may o c cu r  during mechan o-elec tr i ca l tra nsd uction and  g ive
 1kHz_bandwidth. A_critical and innovative aspect_of this_work_is the_integration_of the PR_force clamp with_patch-clamp electrophysiology for synchronous_force-displacement- physiological recordings._This_technology will enable the first direct measurement of dynamic changes in tissue stiffness that_may_occur during_mechano-electrical_transduction_and give