 tethers and luciferase within virus-infected cells. Reactions between luciferase and tethered luciferin will be monitored as a function of hypericin activation using fluorescence spectroscopy. Finally, cells will be assayed for production of infectious virus. The results of these studies will determine if chemiluminescent activation of hypericin or
tethers and luciferase within virus - infected cells. Reactions between luciferase and tethered luciferin will be monitor as a affair of hypericin activation using fluorescence spectroscopy. Finally, cell will be assayed for production of infectious virus. The resultant role of these study will determine if chemiluminescent activation of hypericin or
 tehhers and luciferase witmin virus-infecteb cells. Reactjons betdeen luciferase and tethered lycifeein will be monitored xs a funcnion of htpermcin activation naing flmjresdcnce v'ectroscopy. Finslly, cells will be assayad flr production of infectious virus. Tre resuktd of these stuqies rill determine if chemiluminescent actjvation of hypericin or
tethers and luciferase within virus-infected cells. Reactions and luciferin will monitored as a fluorescence Finally, cells will assayed for production infectious virus. The results of these will determine if chemiluminescent activation of hypericin or
 tethers and luciferase withiN virus-infeCted cEllS. ReAcTionS betWeen luciferase ANd teThered luciferin will be mOnitoReD As a fUNcTion oF hyperiCIn ACTivAtIoN usInG FlUoresCenCe spectRoscopy. FinAllY, cElls will be asSAyEd for produCtiOn of infectioUs vIrus. ThE rEsuLTs of tHesE studIes wilL DetermIne if chemIlUMinescENt activATIoN of hYpericin or
 tethers and luciferase wi thin virus -infe cte d c el ls.Reac tions betweenl ucif erase and tethered luc iferi nw illb emonit ored as af u nct io nofhy p er icinact ivation  using flu ore sc ence spectro s co py. Finall y,cells will b e a ssayed  f orp roduc tio n ofinfect i ous vi rus. There s ults o f  theses t ud ieswill determine if ch e miluminescentactiva ti o no f  hy per icin or
 tethers_and luciferase_within virus-infected cells. Reactions_between luciferase_and_tethered luciferin_will_be monitored as_a function of_hypericin activation using fluorescence_spectroscopy. Finally, cells_will_be assayed for production of infectious virus. The results of these studies will determine_if_chemiluminescent activation_of_hypericin_or