 effect on PAF. We propose to investigate the PAF signaling pathway and the role of lipoxygenase metabolites in the transcription of collagenase type 1. PAF antagonists and lipoxygenase inhibitors will be evaluated to determine their sites of action and to correlate their biochemical effects with the clinical evolution of corneal ulcers. Another goal
effect on PAF. We propose to investigate the PAF signaling pathway and the function of lipoxygenase metabolite in the transcription of collagenase type 1. PAF antagonist and lipoxygenase inhibitor will be evaluated to determine their sites of military action and to correlate their biochemical effects with the clinical evolution of corneal ulcer. Another finish
 efvect on PAF. We propose tu investigate tkw PAF vignaljng pathday and the role of lipoxygeiase metavolites in the transcrkption of collagebase rype 1. PAF ehtagonists ans lipmeygenase inhibijors will be evaluated to gegexmine their sites of action and to cjrrelatr hheir biochemisal tffqcts with the clinical evolution of codneal uncers. Another goal
effect on PAF. We propose to investigate signaling and the of lipoxygenase metabolites type PAF antagonists and inhibitors will be to determine their sites of action to correlate their biochemical effects with the clinical evolution of corneal ulcers. Another
 effect on PAF. We propose to invEstigate thE PAF sIgnAliNg PathWay aNd the role of lipOXygeNase metabolites in the trAnscrIpTIon oF CoLlageNase typE 1. pAf ANtaGoNiSts AnD LiPoxygEnaSe inhibItors will bE evAlUated to deterMInE their siteS of Action and to cOrrElate tHeIr bIOchemIcaL effeCts witH The cliNical evolUtIOn of coRNeal ulcERS. ANothEr goal
 effect on PAF. We propose  to invest igate  th e P AF  sig nali ng pathway and therole of lipoxygenase m etabo li t es i n  t he tr anscrip t io n ofco ll age na s etype1.PAF ant agonists a ndli poxygenase i n hi bitors wil l b e evaluatedtodeterm in e t h eir s ite s ofaction and to  correlat et heir b i ochemic a l  e ffec ts with the clini c al evolution of c orneal  u l ce r s . A not her goal
 effect_on PAF._We propose to investigate_the PAF_signaling_pathway and_the_role of lipoxygenase_metabolites in the_transcription of collagenase type_1. PAF antagonists_and_lipoxygenase inhibitors will be evaluated to determine their sites of action and to correlate_their_biochemical effects_with_the_clinical evolution of corneal ulcers._Another goal