X, where the phosphoacceptor site is followed on the carboxyl-terminus by a proline residue and X can be any amino acid. This grant application has three goals: (1) To define the structural determinants for substrates recognition by ceramide-activated protein kinase and for ceramide stimulation, and determine the intracellular
X, where the phosphoacceptor site is followed on the carboxyl - terminus by a proline residue and ten can be any amino acid. This concession application has three goal: (1) To specify the structural determinants for substrate realization by ceramide - activated protein kinase and for ceramide stimulation, and determine the intracellular
X, wjere the phosphoacceptor site is followgd on thx carbosyl-termivus by a proline residue and X can ve any amino acid. This grant apilication has rhree goals: (1) To dennne tgc strbcvural determinakts for subvtrates recognhtkou by ceramide-activated protein kinasq and fpr ceramide stimolatipg, ans determine the intracellular
X, where the phosphoacceptor site is followed carboxyl-terminus a proline and X can grant has three goals: To define the determinants for substrates recognition by ceramide-activated kinase and for ceramide stimulation, and determine the intracellular
X, where the phosphoacceptor sIte is folloWed on The CarBoXyl-tErmiNus by a proline rESiduE and X can be any amino acid. this gRaNT appLIcAtion Has threE GoALS: (1) To DeFiNe tHe STrUcturAl dEterminAnts for subStrAtEs recognitioN By Ceramide-acTivAted protein kInaSe and fOr CerAMide sTimUlatiOn, and dETerminE the intraCeLLular
X, where the phosphoaccept or site is  foll owe d o nthecarb oxyl-terminusb y aproline residue and Xcan b ea ny a m in o aci d. This gr a n t a pp li cat io n  h as th ree  goals:  (1) To de fin ethe structur a ldeterminan tsfor substrat esrecogn it ion by ce ram ide-a ctivat e d prot ein kinas ea nd for ceramid e st imul ation, and determ i ne the intracellu lar
X, where_the phosphoacceptor_site is followed on_the carboxyl-terminus_by_a proline_residue_and X can_be any amino_acid. This grant application_has three goals:_(1)_To define the structural determinants for substrates recognition by ceramide-activated protein kinase and for_ceramide_stimulation, and_determine_the_intracellular