-1 genes. We have made SHIV clones containing the envelope (env) gene of various HIV-1 subtype-B isolates, and have analyzed these recombinant viruses in vivo in juvenile and newborn macaques. Results A pathogenic SHIV (designated SHIV-33A), containing the env gene of HIV-
-1 genes. We have made SHIV clones containing the envelope (env) gene of diverse HIV-1 subtype - boron isolates, and have analyzed these recombinant viruses in vivo in juvenile and newborn macaque. Results A pathogenic SHIV (designated SHIV-33A), contain the env gene of HIV-
-1 gejes. We have made SHIV clunes containing the entelope (snv) gene of various HIV-1 subtype-B isopares, abd have analyzed these recombinwnt viruwes mn vivo in juvenmme and kzwborh maccqnes. Results A psthogenic VHIV (designateg RHNV-33A), containing the env gene of HIV-
-1 genes. We have made SHIV clones envelope gene of HIV-1 subtype-B isolates, viruses vivo in juvenile newborn macaques. Results pathogenic SHIV (designated SHIV-33A), containing the gene of HIV-
-1 genes. We have made SHIV clones Containing The enVelOpe (EnV) genE of vArious HIV-1 subtyPE-B isOlates, and have analyzed tHese rEcOMbinANt VirusEs in vivO In JUVenIlE aNd nEwBOrN macaQueS. ResultS A pathogenIc ShIv (designated ShiV-33a), containinG thE env gene of HIv-
-1 genes. We have made SHI V clones c ontai nin g t he  env elop e (env) gene o f  var ious HIV-1 subtype-B i solat es ,  and ha ve an alyzedt he s e  re co mb ina nt vi ruses  in  vivo i n juvenile  an dnewborn maca q ue s. Results  Apathogenic S HIV  (desi gn ate d  SHIV -33 A), c ontain i ng the  env gene  o f  HIV-
-1 genes._We have_made SHIV clones containing_the envelope_(env)_gene of_various_HIV-1 subtype-B isolates,_and have analyzed_these recombinant viruses in_vivo in juvenile_and_newborn macaques. Results A pathogenic SHIV (designated SHIV-33A), containing the env gene of HIV-