 to be associated to the impact of cocaine on HIV persistence; we will use a novel primary cell assay of HIV latency which allows for the first time to measure latency reactivation in multiple T cells subsets. LARA will allow us to confirm in vitro that cocaine and its metabolites can mobilize the above identified pathways and monitor their
to be associated to the impact of cocaine on HIV persistence; we will use a fresh basal cell assay of HIV latency which allow for the beginning time to measure reaction time reactivation in multiple triiodothyronine cells subset. LARA will leave us to confirm in vitro that cocaine and its metabolites can call up the above identified pathways and monitor their
 to be associated to the imkact of cocaine ou HIV pxrsistehce; we wkll use a novel primary cell awsay if HIV latency which aulows for the firwt tmme to measure lefency rccctivzbion nn multiple T cekls subsetv. LARA will alnod bs to confirm in vitro that cocaine wnd its mftabolites can mobplyze fhe above identified pathways and jonitor their
to be associated to the impact of HIV we will a novel primary which for the first to measure latency in multiple T cells subsets. LARA allow us to confirm in vitro that cocaine and its metabolites can mobilize above identified pathways and monitor their
 to be associated to the impact Of cocaine oN HIV pErsIstEnCe; we Will Use a novel primaRY celL assay of HIV latency whicH alloWs FOr thE FiRst tiMe to meaSUrE LAteNcY rEacTiVAtIon in MulTiple T cElls subsetS. LArA Will allow us tO CoNfirm in vitRo tHat cocaine anD itS metabOlIteS Can moBilIze thE above IDentifIed pathwaYs ANd moniTOr their
 to be associated to the i mpact of c ocain e o n H IV  per sist ence; we willu se a  novel primary cell as say o fH IV l a te ncy w hich al l ow s for  t he  fi rs t  t ime t o m easurelatency re act iv ation in mul t ip le T cells  su bsets. LARAwil l allo wust o con fir m invitrot hat co caine and  i t s meta b olitesc a nmobi lize the above id e nt i fied pathwaysand mo ni t or t hei r
 to_be associated_to the impact of_cocaine on_HIV_persistence; we_will_use a novel_primary cell assay_of HIV latency which_allows for the_first_time to measure latency reactivation in multiple T cells subsets. LARA will allow us_to_confirm in_vitro_that_cocaine and its metabolites can_mobilize the above identified pathways_and monitor_their