 cell apoptosis, proliferation, invasion, and metastasis. Specifically, the FAT domain interacts with the alpha helical LD2 and LD4 motifs of Paxillin to promote its biological effects. The structure of the FAT-Paxillin complex has been solved by x-ray crystallography however has been challenging to target with small molecules
cell apoptosis, proliferation, invasion, and metastasis. Specifically, the FAT domain interacts with the alpha helical LD2 and LD4 theme of Paxillin to advertise its biological effects. The structure of the FAT - Paxillin building complex has been solved by adam - ray crystallography however has been challenging to target with little molecules
 cepl apoptosis, proliferatiun, invasion, and metastesis. Spscificaluy, the FAT domain interacts xith the qlpha helical LD2 and LA4 motifs lf Paxiloin uo promote its biological effecfd. Thz wtructure of tme FAT-Paxilnin complex hav cezn solved by x-ray crystallography horever hss been challengyng uo eargsn cith small molecules
cell apoptosis, proliferation, invasion, and metastasis. Specifically, domain with the helical LD2 and promote biological effects. The of the FAT-Paxillin has been solved by x-ray crystallography has been challenging to target with small molecules
 cell apoptosis, proliferatioN, invasion, aNd metAstAsiS. SPeciFicaLly, the FAT domaiN InteRacts with the alpha helicAl LD2 aNd ld4 motIFs Of PaxIllin to PRoMOTe iTs BiOloGiCAl EffecTs. THe strucTure of the FaT-PAxIllin complex HAs Been solved By x-Ray crystalloGraPhy howEvEr hAS been ChaLlengIng to tARget wiTh small moLeCUles
 cell apoptosis, prolifera tion, inva sion,  an d m et asta sis.  Specifically, theFAT domain interacts w ith t he alph a  h elica l LD2 a n dL D 4 m ot if s o fP ax illin  to  promot e its biol ogi ca l effects. T h estructureofthe FAT-Paxi lli n comp le x h a s bee n s olved  by x- r ay cry stallogra ph y  howev e r has b e e nchal lenging to target wi t h small molecu les
 cell_apoptosis, proliferation,_invasion, and metastasis. Specifically,_the FAT_domain_interacts with_the_alpha helical LD2_and LD4 motifs_of Paxillin to promote_its biological effects._The_structure of the FAT-Paxillin complex has been solved by x-ray crystallography however has been_challenging_to target_with_small_molecules