. The focus of this proposal is to optimize ex vivo culture of CB to provide increased numbers of cells to enable the use of CB in adult patients. In addition, optimization of the expansion cultures will enable more rapid hematopoietic and immune recovery post transplant and potentially minimize other complications associated with transplantation of CB. The first aim of these
. The focus of this proposal is to optimize ex vivo culture of CB to leave increase numbers of cells to enable the use of CB in adult affected role. In addition, optimization of the expansion cultures will enable more rapid hematopoietic and immune convalescence post transplant and potentially minimize early complication associated with transplant of CB. The first aim of these
. Thf focus of this proposal is to optimize ex vivm culthre of CC to provide increased numbecs od celos to enable the use ow CB in afult patuentw. In addition, optimlvatioh of chx expansion culjures will etable more raphd hzmatopoietic and immune recovery pose transllwnt and potentyallj iinijpzt other complications associated sith trensplantation og CB. The first aim of thesf
. The focus of this proposal is ex culture of to provide increased the of CB in patients. In addition, of the expansion cultures will enable rapid hematopoietic and immune recovery post transplant and potentially minimize other complications associated transplantation of CB. The first aim of these
. The focus of this proposal is tO optimize eX vivo CulTurE oF CB tO proVide increased nUMberS of cells to enable the use Of CB iN aDUlt pATiEnts. IN additiON, oPTImiZaTiOn oF tHE eXpansIon CultureS will enablE moRe Rapid hematopOIeTic and immuNe rEcovery post tRanSplant AnD poTEntiaLly MinimIze othER complIcations aSsOCiated WIth tranSPLaNtatIon of CB. The first aiM Of THese
. The focus of this propos al is to o ptimi zeexvi vo c ultu re of CB to pr o vide  increased numbers ofcells  t o  ena b le  theuse ofC Bi n  ad ul tpat ie n ts . Inadd ition,optimizati onof  the expansi o ncultures w ill  enable more  ra pid he ma top o ietic  an d imm une re c overypost tran sp l ant an d  potent i a ll y mi nimize other comp l ic a tions associat ed wit ht ra n s pla nta tion of CB .The f i rst aim of t h ese 
. The_focus of_this proposal is to_optimize ex_vivo_culture of_CB_to provide increased_numbers of cells_to enable the use_of CB in_adult_patients. In addition, optimization of the expansion cultures will enable more rapid hematopoietic and_immune_recovery post_transplant_and_potentially minimize other complications associated_with transplantation of CB. The_first aim_of these