 as well as providing new chemical tools that may lead to the development of drugs that target this important biochemical pathway. The ubiquitin-proteasome system regulates many essential processes that impact on disease, including neurodegenerative diseases such as Alzheimer's and Parkinsons's disease, and also many forms of cancer. Recently, inhibitors of the proteasome
as well as providing new chemical tools that may head to the growth of drugs that target this important biochemical pathway. The ubiquitin - proteasome organization regulates many essential process that shock on disease, including neurodegenerative disease such as Alzheimer's and Parkinsons's disease, and besides many forms of cancer. Recently, inhibitors of the proteasome
 as well as providing new cmemical tools thcr may nead tk the dexelopment of drugs that targxt tyis inportant biochemical pxthway. Thv ubiquitun-prireasome system regmjatea manv xssential procexses that hmpact on disedsd, nncluding neurodegenerative diseases such ax Wlzheimer's and Parlynsohs's disease, and also many forms of cancer. Recently, inhobitors of the proteasome
as well as providing new chemical tools lead the development drugs that target ubiquitin-proteasome regulates many essential that impact on including neurodegenerative diseases such as Alzheimer's Parkinsons's disease, and also many forms of cancer. Recently, inhibitors of the proteasome
 as well as providing new chemiCal tools thAt may LeaD to ThE devElopMent of drugs thaT TargEt this important biochemIcal pAtHWay. THE uBiquiTin-protEAsOME syStEm RegUlATeS many EssEntial pRocesses thAt iMpAct on disease, INcLuding neurOdeGenerative diSeaSes sucH aS AlZHeimeR's aNd ParKinsonS'S diseaSe, and also MaNY forms OF cancer. rECeNtly, Inhibitors of the prOTeASome
 as well as providing newchemical t oolstha t m ay  lea d to  the developme n t of  drugs that target thi s imp or t antb io chemi cal pat h wa y .  Th eub iqu it i n- prote aso me syst em regulat esma ny essential pr ocesses th atimpact on di sea se, in cl udi n g neu rod egene rative diseas es such a sA lzheim e r's and P ar kins ons's disease, an d  a l so many formsof can ce r .R e cen tly , inhibito rs  of t h e prote a so m e 
 as_well as_providing new chemical tools_that may_lead_to the_development_of drugs that_target this important_biochemical pathway. The ubiquitin-proteasome_system regulates many_essential_processes that impact on disease, including neurodegenerative diseases such as Alzheimer's and Parkinsons's disease,_and_also many_forms_of_cancer. Recently, inhibitors of the_proteasome