 multiple affected members. Once the HSS gene has been mapped, we will search for mutations in candidate genes, as well as identify novel transcribed sequences that may contain the HSS gene. We will then characterize the gene and its protein product through homology studies to known sequences. Knowledge of the molecular basis of this disease will lead
multiple affected members. Once the HSS gene has been mapped, we will search for mutation in campaigner genes, as well as name novel transcribe sequences that may check the HSS gene. We will then qualify the gene and its protein product through homology studies to known sequences. Knowledge of the molecular basis of this disease will head
 muptiple affected members. Unce the HSS geuw has ueen malped, we dill search for mutations in cqndidqte genes, as well as iaentify nlvel trabscrmbed sequences tizt may gjntajk the ISS gene. We wilk then chasacterize the ceve and its protein product through hoiology xtkdies to known seqlegces. Knowledge of the molecular basis kf this disease will lead
multiple affected members. Once the HSS gene mapped, will search mutations in candidate novel sequences that may the HSS gene. will then characterize the gene and protein product through homology studies to known sequences. Knowledge of the molecular basis this disease will lead
 multiple affected members. OnCe the HSS geNe has BeeN maPpEd, we Will Search for mutatIOns iN candidate genes, as well aS idenTiFY novEL tRanscRibed seQUeNCEs tHaT mAy cOnTAiN the HsS gEne. We wiLl then charActErIze the gene anD ItS protein prOduCt through homOloGy studIeS to KNown sEquEnces. knowleDGe of thE moleculaR bASis of tHIs diseaSE WiLl leAd
 multiple affected members . Once the  HSSgen e h as  bee n ma pped, we wills earc h for mutations in can didat eg enes ,  a s wel l as id e nt i f y n ov el  tr an s cr ibedseq uencesthat may c ont ai n the HSS ge n e.  We will t hen  characteriz e t he gen eand its p rot ein p roduct throug h homolog ys tudies to know n se quen ces. Knowledge of th e  molecular bas is ofth i sd i sea sewill lead
 multiple_affected members._Once the HSS gene_has been_mapped,_we will_search_for mutations in_candidate genes, as_well as identify novel_transcribed sequences that_may_contain the HSS gene. We will then characterize the gene and its protein product_through_homology studies_to_known_sequences. Knowledge of the molecular_basis of this disease will_lead