 to characterize the haplotype specific nature of suppression of EAE using F1 restricted T cell lines and clones. These experiments will define the genetic and antigenetic specifity of inhibition of disease using auto antigens and synthetic antigens whos immune response is under IR gene control. At present, the mechanism by which IR genes confer susceptibility
to characterize the haplotype specific nature of suppression of EAE using F1 restricted metric ton cellular telephone lines and clones. These experiment will specify the genetic and antigenetic specifity of inhibition of disease use car antigens and synthetic antigens who s immune response is under IR gene control. At present, the mechanism by which IR gene confer susceptibility
 to characterize the haplotnpe specific natorw of snppressjon of EXE using F1 restricted T cell lunes qnd clones. These experkments wipl definw tht genetic and antmfenetic specirlty oy mnhibition of dlsease usinc auto antigenv xnb synthetic antigens whos immune res[onse ix knder IR gene sontgoj. At irtsent, the mechanism by which IR gsnes coifer susceptibikity
to characterize the haplotype specific nature of EAE F1 restricted cell lines and the and antigenetic specifity inhibition of disease auto antigens and synthetic antigens whos response is under IR gene control. At present, the mechanism by which IR confer susceptibility
 to characterize the haplotypE specific nAture Of sUppReSsioN of EaE using F1 restriCTed T Cell lines and clones. ThesE expeRiMEnts WIlL defiNe the geNEtIC And AnTiGenEtIC sPecifIty Of inhibItion of disEasE uSing auto antiGEnS and syntheTic Antigens whos ImmUne resPoNse IS undeR IR Gene cOntrol. aT preseNt, the mechAnISm by whICh IR genES CoNfer Susceptibility
 to characterize the haplo type speci fic n atu reof  sup pres sion of EAE us i ng F 1 restricted T cell li nes a nd clon e s.  Thes e exper i me n t s w il ldef in e  t he ge net ic andantigeneti c s pe cifity of in h ib ition of d ise ase using au toantige ns  an d  synt het ic an tigens whos i mmune res po n se isu nder IR g en e co ntrol. At present ,  t h e mechanism by  which  I R  g e n escon fer suscep ti bilit y 
 to_characterize the_haplotype specific nature of_suppression of_EAE_using F1_restricted_T cell lines_and clones. These_experiments will define the_genetic and antigenetic_specifity_of inhibition of disease using auto antigens and synthetic antigens whos immune response is_under_IR gene_control._At_present, the mechanism by which_IR genes confer susceptibility