 We hypothesized that the cause of recessive OI with abnormal collagen biochemistry and normal collagen gene sequence would involve a gene(s) whose products interacted with type I collagen. Ten years ago we identified defects in two components of the collagen prolyl 3-hydroxylation complex, CRTAP and P3H1
We hypothesized that the cause of recessive OI with abnormal collagen biochemistry and normal collagen gene sequence would imply a gene(s) whose product interacted with type I collagen. Ten years ago we name defects in two components of the collagen prolyl 3 - hydroxylation building complex, CRTAP and P3H1
 We hypothesized that the cxuse of recessirw OI wmth abnkrmal coulagen biochemistry and normel cillagtu gene sequence woula involve a gene(s) whoww products interacbzd wifm typz M collagen. Ten iears ago we identified dexeztd in two components of the collagen prolyl 3-hjdroxylation cjmpltx, SRTAL and P3H1
We hypothesized that the cause of recessive abnormal biochemistry and collagen gene sequence products with type I Ten years ago identified defects in two components of collagen prolyl 3-hydroxylation complex, CRTAP and P3H1
 We hypothesized that the causE of recessiVe OI wIth AbnOrMal cOllaGen biochemistrY And nOrmal collagen gene sequeNce woUlD InvoLVe A gene(S) whose pROdUCTs iNtErActEd WItH type i coLlagen. TEn years ago We iDeNtified defecTS iN two componEntS of the collagEn pRolyl 3-hYdRoxYLatioN coMplex, cRTAP aND P3H1
 We hypothesized that thecause of r ecess ive  OI  w ithabno rmal collagenb ioch emistry and normal col lagen  g e ne s e qu encewould i n vo l v e a  g en e(s )w ho se pr odu cts int eracted wi thty pe I collage n .Ten yearsago  we identifi eddefect sint wo co mpo nents  of th e  colla gen proly l3 -hydro x ylation c om plex , CRTAP and P3H1
 We_hypothesized that_the cause of recessive_OI with_abnormal_collagen biochemistry_and_normal collagen gene_sequence would involve_a gene(s) whose products_interacted with type_I_collagen. Ten years ago we identified defects in two components of the collagen prolyl_3-hydroxylation_complex, CRTAP_and_P3H1