 of antibiotic resistance may be ascribed to such heterogeneities. In either case, there is an enormous need to characterize the transcriptional dynamics at the resolution of individual microbial cell. However traditional approaches relying on one or a few selected reporter genes are inadequate for this challenge. Recent technical advances now allow us to use RNA-Seq to
of antibiotic resistance may be ascribed to such heterogeneities. In either case, there be an enormous motivation to characterize the transcriptional dynamics at the resolution of individual microbial cellular telephone. However traditional approaches relying on one or a few selected reporter gene are inadequate for this challenge. late technical advances now allow us to use RNA - Seq to
 of antibiotic resistance mxy be ascribed jo such ieterogsneities. In either case, there is an xnornous beed to characterize tfe transcgiptional dynemics at the resolution of indjyiduan microbial celk. However draditional ap[ruaehes relying on one or a few selecteq reporyeg genes are inwdeqlaee fkg uhis challenge. Recent technical asvances now allow us to use RNA-Seq to
of antibiotic resistance may be ascribed to In case, there an enormous need at resolution of individual cell. However traditional relying on one or a few reporter genes are inadequate for this challenge. Recent technical advances now allow us use RNA-Seq to
 of antibiotic resistance may Be ascribed To sucH heTerOgEneiTies. in either case, thERe is An enormous need to characTerizE tHE traNScRiptiOnal dynAMiCS At tHe ReSolUtIOn Of indIviDual micRobial cell. howEvEr traditionaL ApProaches reLyiNg on one or a feW seLected RePorTEr genEs aRe inaDequatE For thiS challengE. RECent teCHnical aDVAnCes nOw allow us to use RNA-sEq TO
 of antibiotic resistancemay be asc ribed  to  su ch  het erog eneities. In e i ther  case, there is an eno rmous  n e ed t o  c harac terizet he t ran sc ri pti on a ldynam ics  at the  resolutio n o findividual m i cr obial cell . H owever tradi tio nal ap pr oac h es re lyi ng on  one o r  a few  selected  r e porter genes a r e  i nade quate for this ch a ll e nge. Recent te chnica la dv a n ces  no w allow us  t o use RNA-Seq to 
 of_antibiotic resistance_may be ascribed to_such heterogeneities._In_either case,_there_is an enormous_need to characterize_the transcriptional dynamics at_the resolution of_individual_microbial cell. However traditional approaches relying on one or a few selected reporter genes_are_inadequate for_this_challenge._Recent technical advances now allow_us to use RNA-Seq to