 and oxidation of Dna. Alkylated DNA bases in tissues will be determined by immunostaining and immunoassays and levels of 8-hydroxydeoxyguanosine, as a measure of oxidative DNA damage, will be detected by HPLC with electrochemical detection. Unknown carcinogen spectrometry. Bacterial enzymes responsible for nitrosation
and oxidation of Dna. Alkylated DNA bases in tissues will be determined by immunostaining and immunoassays and degree of 8 - hydroxydeoxyguanosine, as a standard of oxidative DNA damage, will be detected by HPLC with electrochemical signal detection. Unknown carcinogen spectrometry. Bacterial enzymes creditworthy for nitrosation
 anf oxidation of Dna. Alkylxted DNA bases nb tissnes wilm be detdrmined by immunostaining anv imnunoawsays and levels of 8-hyaroxydeoxjguanosinw, as q measure of oxidabnve DHW dakege, will be detgcted by HPLW with electrowhdmncal detection. Unknown carcinogen spqctromeyrj. Bacterial eneymes wespknsible for nitrosation
and oxidation of Dna. Alkylated DNA bases will determined by and immunoassays and measure oxidative DNA damage, be detected by with electrochemical detection. Unknown carcinogen spectrometry. enzymes responsible for nitrosation
 and oxidation of Dna. AlkylateD DNA bases iN tissUes WilL bE detErmiNed by immunostaINing And immunoassays and leveLs of 8-hYdROxydEOxYguanOsine, as A MeASUre Of OxIdaTiVE DnA damAge, Will be dEtected by HpLC WiTh electrocheMIcAl detectioN. UnKnown carcinoGen SpectrOmEtrY. bacteRiaL enzyMes resPOnsiblE for nitroSaTIon
 and oxidation of Dna. Alk ylated DNA  base s i n t is sues  wil l be determine d  byimmunostaining and imm unoas sa y s an d  l evels  of 8-h y dr o x yde ox yg uan os i ne , asa m easureof oxidati veDN A damage, wi l lbe detecte d b y HPLC withele ctroch em ica l  dete cti on. U nknown carcin ogen spec tr o metry. Bacteri a l  e nzym es responsible fo r  n i trosation
 and_oxidation of_Dna. Alkylated DNA bases_in tissues_will_be determined_by_immunostaining and immunoassays_and levels of_8-hydroxydeoxyguanosine, as a measure_of oxidative DNA_damage,_will be detected by HPLC with electrochemical detection. Unknown carcinogen spectrometry. Bacterial enzymes responsible_for_nitrosation