 the hydrogel membrane composition and thickness, the enzyme reaction, the device geometry, and the molecular properties of GnRH on the pulsatile release pattern will be studied. We will investigate device behavior in buffers and simulated plasma, when challenged with constant levels of glucose and programs of glucose fluctuations that are observed in nondiabetic individuals.
the hydrogel membrane composition and thickness, the enzyme reaction, the device geometry, and the molecular properties of GnRH on the pulsatile release design will be study. We will investigate device behavior in buffers and simulated plasma, when challenge with constant levels of glucose and platform of glucose variation that are observed in nondiabetic individuals.
 thf hydrogel membrane compusition and thiejness, vhe enzgme reacgion, the device geometry, and tye mooecular properties of EnRH on tje pulsarile eelease pavfern will be abudieb. Xe will investinate device behavior in bgfwexs and simulated plasma, when challended witn fonstant levelf of dluckse and programs of glucose fluctuztions uhat are observed on nondiabetic individuals.
the hydrogel membrane composition and thickness, the the geometry, and molecular properties of pattern be studied. We investigate device behavior buffers and simulated plasma, when challenged constant levels of glucose and programs of glucose fluctuations that are observed in individuals.
 the hydrogel membrane composItion and thIckneSs, tHe eNzYme rEactIon, the device geOMetrY, and the molecular properTies oF GNrH on THe PulsaTile relEAsE PAttErN wIll Be STuDied. WE wiLl invesTigate deviCe bEhAvior in buffeRS aNd simulateD plAsma, when chalLenGed witH cOnsTAnt leVelS of glUcose aND progrAms of glucOsE FluctuATions thAT ArE obsErved in nondiabetiC InDIviduals.
 the hydrogel membrane com position a nd th ick nes s,  the  enz yme reaction,t he d evice geometry, and th e mol ec u larp ro perti es of G n RH o n t he  p uls at i le  rele ase  patter n will bestu di ed. We willi nv estigate d evi ce behaviorinbuffer sand simul ate d pla sma, w h en cha llenged w it h  const a nt leve l s  o f gl ucose and program s  o f  glucose fluct uation st ha t are  ob served inno ndiab e tic ind i vi d u a ls. 
 the_hydrogel membrane_composition and thickness, the_enzyme reaction,_the_device geometry,_and_the molecular properties_of GnRH on_the pulsatile release pattern_will be studied._We_will investigate device behavior in buffers and simulated plasma, when challenged with constant levels_of_glucose and_programs_of_glucose fluctuations that are observed_in nondiabetic individuals.