 in airway remodeling. We will: 1) Evaluate the hypothesis that the reduced expression of cav1 is associated with the expression of inflammatory markers, more specifically IL-4 and TGF-beta, and the development of airway remodeling in allergen challenged mice. 2) Investigate the hypothesis that among the Th2 cytokines expressed
in airway remodeling. We will: 1) Evaluate the hypothesis that the dilute formula of cav1 is associated with the expression of inflammatory marker, more specifically IL-4 and TGF - beta, and the development of airway recast in allergen challenge mice. 2) Investigate the guess that among the Th2 cytokine expressed
 in airway remodeling. We wiul: 1) Evaluate thg yypothxsis thzt the rdduced expression of cav1 is essoxiatee with the expression uf inflamlatory mqrkecs, more specificemly IL-4 and TGR-neta, cnv the developmekt of airwaf remodeling it xlpergen challenged mice. 2) Investigate the hylohhesis that amjng uhe Th2 djtikines expressed
in airway remodeling. We will: 1) Evaluate that reduced expression cav1 is associated markers, specifically IL-4 and and the development airway remodeling in allergen challenged mice. Investigate the hypothesis that among the Th2 cytokines expressed
 in airway remodeling. We will: 1) EValuate the HypotHesIs tHaT the ReduCed expression oF Cav1 iS associated with the exprEssioN oF InflAMmAtory Markers, MOrE SPecIfIcAllY Il-4 AnD TGF-bEta, And the dEvelopment Of aIrWay remodelinG In Allergen chAllEnged mice. 2) InvEstIgate tHe HypOThesiS thAt amoNg the TH2 CytokiNes expresSeD
 in airway remodeling. Wewill: 1) E valua tethe  h ypot hesi s that the red u cedexpression of cav1 isassoc ia t ed w i th  theexpress i on o f i nf la mma to r ymarke rs,  more s pecificall y I L- 4 and TGF-be t a,  and the d eve lopment of a irw ay rem od eli n g inall ergen  chall e nged m ice. 2) I nv e stigat e  the hy p o th esis  that among the T h 2c ytokines expre ssed
 in_airway remodeling._We will: 1) Evaluate_the hypothesis_that_the reduced_expression_of cav1 is_associated with the_expression of inflammatory markers,_more specifically IL-4_and_TGF-beta, and the development of airway remodeling in allergen challenged mice. 2) Investigate the_hypothesis_that among_the_Th2_cytokines expressed