 of bone markers. Only type I collagen shows similar expression pattern in both mutations, with decreased expression, secretion and matrix incorporation. Type XIV OI is a moderately severe form of OI which was identified in 2013. It is caused by recessive defects in TMEM38B, which encodes TRIC-B,
of bone markers. Only type I collagen shows exchangeable formula pattern in both mutations, with decreased formulation, secretion and matrix incorporation. Type XIV OI is a moderately hard form of OI which was identified in 2013. It is cause by recessive defects in TMEM38B, which encode TRIC - B,
 of bone markers. Only type L collagen shows similac expreasion pagtern in both mutations, with dwcreawed expression, secretiun and manrix incoeporetion. Type XIV OM is a moderatspy szvxre form of OI ehich was hdentified in 2013. Ig ns caused by recessive defects in TMQM38B, whivh encodes TRIC-B,
of bone markers. Only type I collagen expression in both with decreased expression, XIV is a moderately form of OI was identified in 2013. It is by recessive defects in TMEM38B, which encodes TRIC-B,
 of bone markers. Only type I colLagen shows SimilAr eXprEsSion PattErn in both mutatIOns, wIth decreased expression, SecreTiON and MAtRix inCorporaTIoN. tYpe xIv Oi is A mODeRatelY seVere forM of OI which Was IdEntified in 2013. It IS cAused by recEssIve defects in tMEm38B, whicH eNcoDEs TRIc-B,
 of bone markers. Only typ e I collag en sh ows  si mi larexpr ession pattern in b oth mutations, with de creas ed expr e ss ion,secreti o na n d m at ri x i nc o rp orati on.  Type X IV OI is a  mo de rately sever e  f orm of OIwhi ch was ident ifi ed in20 13. It is  ca usedby rec e ssivedefects i nT MEM38B ,  whiche n co desTRIC-B,
 of_bone markers._Only type I collagen_shows similar_expression_pattern in_both_mutations, with decreased_expression, secretion and_matrix incorporation. Type XIV_OI is a_moderately_severe form of OI which was identified in 2013. It is caused by recessive_defects_in TMEM38B,_which_encodes_TRIC-B,