 PIL proteins will be further characterized. Cloned CDNAS for these interstitial proteins will be isolated and their structure characterized. Moreover, specific probes will be generated for use in determining both physiological and aberrant expression of these proteins in vivo and in vitro studies. Regulation of these interstitial proteins will be studied by analysis of their M
PIL proteins will be further characterized. Cloned CDNAS for these interstitial proteins will be sequester and their social organization characterized. Moreover, specific probe will be render for use in determining both physiologic and aberrant expression of these proteins in vivo and in vitro studies. rule of these interstitial protein will be studied by analysis of their megabyte
 PIP proteins will be furthtr characterized. Eooned RDNAS fkr these interstitial proteins will ue iwolattb and their structurd charactvrized. Moeeovtr, specific probes will bc gensvated hor use in detetmining both physiological avd aberrant expression of these proteyns in figo and in vitrj stldyes. Dvgmlation of these interstitial prkteins xill be studied by analysis of their M
PIL proteins will be further characterized. Cloned these proteins will isolated and their will generated for use determining both physiological aberrant expression of these proteins in and in vitro studies. Regulation of these interstitial proteins will be studied by of their M
 PIL proteins will be further cHaracterizEd. CloNed cDNaS For tHese Interstitial prOTeinS will be isolated and theiR struCtURe chARaCteriZed. MoreOVeR, SPecIfIc ProBeS WiLl be gEneRated foR use in deteRmiNiNg both physioLOgIcal and abeRraNt expression Of tHese prOtEinS In vivO anD in viTro stuDIes. RegUlation of ThESe inteRStitial PROtEins Will be studied by anALySIs of their M
 PIL proteins will be furt her charac teriz ed.  Cl on ed C DNAS  for these int e rsti tial proteins will beisola te d  and th eir s tructur e  c h a rac te ri zed .M or eover , s pecific  probes wi llbe  generated f o ruse in det erm ining both p hys iologi ca l a n d abe rra nt ex pressi o n of t hese prot ei n s in v i vo andi n  v itro  studies. Regulat i on of these inter stitia lp ro t e ins  wi ll be stud ie d bya nalysis of t h eir M
 PIL_proteins will_be further characterized. Cloned_CDNAS for_these_interstitial proteins_will_be isolated and_their structure characterized._Moreover, specific probes will_be generated for_use_in determining both physiological and aberrant expression of these proteins in vivo and in_vitro_studies. Regulation_of_these_interstitial proteins will be studied_by analysis of their M