 hippocampus will be correlated with their susceptibility to epilepsy associated damage. Similar studies will be carried out in rats with seizures induced by graded electrical stimulation. Because the hippocampal somatostatin interneuron appears to be an early excitotoxic target, and thus of possible significance in the pathogenesis of TLE, we will particularly focus on the
hippocampus will be correlated with their susceptibility to epilepsy associated damage. Similar report will be carry out in rats with seizures induced by grade electrical stimulation. Because the hippocampal somatostatin interneuron appear to be an early excitotoxic aim, and thus of potential meaning in the pathogenesis of TLE, we will particularly focus on the
 hiopocampus will be correlxted with their suscepvibilitg to epiuepsy associated damage. Simipae stueies will be carried ojt in ratd with swizuces induced by gczded elcetriczp stnmnlation. Because the hippowampal somatosdagiu interneuron appears to be an early excitoyodic target, and thux of lossible significance in the pathofenesis of TLE, we wikl particularly focus on tje
hippocampus will be correlated with their susceptibility associated Similar studies be carried out by electrical stimulation. Because hippocampal somatostatin interneuron to be an early excitotoxic target, thus of possible significance in the pathogenesis of TLE, we will particularly focus the
 hippocampus will be correlatEd with theiR suscEptIbiLiTy to EpilEpsy associated DAmagE. Similar studies will be cArrieD oUT in rATs With sEizures INdUCEd bY gRaDed ElECtRical StiMulatioN. Because thE hiPpOcampal somatOStAtin internEurOn appears to bE an Early eXcItoTOxic tArgEt, and Thus of POssiblE significAnCE in the PAthogenESIs Of TLe, we will particularLY fOCus on the
 hippocampus will be corre lated with  thei r s usc ep tibi lity  to epilepsy a s soci ated damage. Similar s tudie sw illb ecarri ed outi nr a tswi th  se iz u re s ind uce d by gr aded elect ric al  stimulation .  B ecause the  hi ppocampal so mat ostati nint e rneur onappea rs tob e an e arly exci to t oxic t a rget, a n d  t husof possible signi f ic a nce in the pat hogene si s  o f TLE , w e will par ti cular l y focus on t h e
 hippocampus_will be_correlated with their susceptibility_to epilepsy_associated_damage. Similar_studies_will be carried_out in rats_with seizures induced by_graded electrical stimulation._Because_the hippocampal somatostatin interneuron appears to be an early excitotoxic target, and thus of_possible_significance in_the_pathogenesis_of TLE, we will particularly_focus on the