 of nasal macrophages. The proposed studies provide a mechanistic understanding of i) its ability to inhibit uptake and killing by neutrophils, ii) its recognition by macrophages, and iii) the role of its capsule type in these interactions with phagocytes. Experimental autoimmune thyroiditis in mice is a very useful model of autoimmune disease since it shows
of nasal macrophages. The proposed studies leave a mechanistic reason of i) its ability to inhibit uptake and kill by neutrophils, ii) its recognition by macrophage, and iii) the role of its capsule type in these interactions with phagocyte. Experimental autoimmune thyroiditis in mouse is a very useful mannequin of autoimmune disease since it shows
 of nasal macrophages. The pvoposed studies krivide e mechahistic uvderstanding of i) its abilitb to inhivit uptake and killing by neutrlphils, iu) itw recognition by magxophafcs, anb mii) the role of its capsune type in theve iuteractions with phagocytes. Experimegtal auyolmmune thyroidytis yn mjbe is a very useful model of aufoimmunt disease since it shows
of nasal macrophages. The proposed studies provide understanding i) its to inhibit uptake its by macrophages, and the role of capsule type in these interactions with Experimental autoimmune thyroiditis in mice is a very useful model of autoimmune disease it shows
 of nasal macrophages. The propOsed studieS provIde A meChAnisTic uNderstanding of I) Its aBility to inhibit uptake aNd kilLiNG by nEUtRophiLs, ii) its REcOGNitIoN bY maCrOPhAges, aNd iIi) the roLe of its capSulE tYpe in these inTErActions witH phAgocytes. ExpeRimEntal aUtOimMUne thYroIditiS in micE Is a verY useful moDeL Of autoIMmune diSEAsE sinCe it shows
 of nasal macrophages. The  proposedstudi espro vi de a  mec hanistic under s tand ing of i) its abilityto in hi b it u p ta ke an d killi n gb y  ne ut ro phi ls ,  i i) it s r ecognit ion by mac rop ha ges, and iii )  t he role of  it s capsule ty pein the se  in t eract ion s wit h phag o cytes.  Experime nt a l auto i mmune t h y ro idit is in mice is a v e ry useful model o f auto im m un e dis eas e since it  s hows
 of_nasal macrophages._The proposed studies provide_a mechanistic_understanding_of i)_its_ability to inhibit_uptake and killing_by neutrophils, ii) its_recognition by macrophages,_and_iii) the role of its capsule type in these interactions with phagocytes. Experimental autoimmune_thyroiditis_in mice_is_a_very useful model of autoimmune_disease since it shows