 types express functional GABAA receptors. However, the mechanism of this immune modulation is unknown. In this proposal, we present exciting preliminary data demonstrating that mice lacking expression of the GABAA receptor?4 subunit (gabra4), a subunit expressed in immune cells including CD4+ lymphocytes, have significantly greater lung
types express functional GABAA receptors. However, the mechanism of this immune transition is strange. In this proposal, we present exciting preliminary data demonstrating that shiner lacking expression of the GABAA receptor?4 fractional monetary unit (gabra4), a subunit expressed in immune cells include CD4 + lymphocytes, have importantly greater lung
 tyoes express functional GXBAA receptors. Kiwever, the mschanism of this immune modulation id ynknoqn. In this proposal, we present vxciting prelmminary data demonstratiky thaf micz oacking expresxion of tha GABAA receptmr?4 sbbunit (gabra4), a subunit expressed in ymmune vepls including SD4+ ljm[hocgnew, have significantly greater mung
types express functional GABAA receptors. However, the this modulation is In this proposal, demonstrating mice lacking expression the GABAA receptor?4 (gabra4), a subunit expressed in immune including CD4+ lymphocytes, have significantly greater lung
 types express functional GABaA receptorS. HoweVer, The MeChanIsm oF this immune modULatiOn is unknown. In this propoSal, we PrESent EXcIting PrelimiNArY DAta DeMoNstRaTInG that MicE lackinG expressioN of ThE GABAA receptOR?4 sUbunit (gabrA4), a sUbunit expresSed In immuNe CelLS inclUdiNg CD4+ lYmphocYTes, havE significAnTLy greaTEr lung
 types express functionalGABAA rece ptors . H owe ve r, t he m echanism of th i s im mune modulation is unk nown.  I n  thi s  p ropos al, wep re s e ntex ci tin gp re limin ary  data d emonstrati ngth at mice lack i ng  expressio n o f the GABAArec eptor? 4sub u nit ( gab ra4),  a sub u nit ex pressed i ni mmunec ells in c l ud ingCD4+ lymphocytes, ha v e significantl y grea te r  l u n g
 types_express functional_GABAA receptors. However, the_mechanism of_this_immune modulation_is_unknown. In this_proposal, we present_exciting preliminary data demonstrating_that mice lacking_expression_of the GABAA receptor?4 subunit (gabra4), a subunit expressed in immune cells including CD4+_lymphocytes,_have significantly_greater_lung