, light and ultrastructural microscopical analyses, and computational modeling to address these objectives through the use of physiologically identified nociceptors and anatomically and physiologically identified subsets of second-order spinal interneurons. Detailed knowledge of the cellular mechanisms underlying the normal balance between excitatory and inhibitory interconnections that
, light and ultrastructural microscopical analyses, and computational modeling to cover these aim through the use of physiologically identified nociceptors and anatomically and physiologically identify subset of second - order spinal interneurons. Detailed knowledge of the cellular mechanisms underlie the normal balance between excitatory and inhibitory interconnections that
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, light and ultrastructural microscopical analyses, and to these objectives the use of and identified subsets of spinal interneurons. Detailed of the cellular mechanisms underlying the balance between excitatory and inhibitory interconnections that
, light and ultrastructural miCroscopicaL analYseS, anD cOmpuTatiOnal modeling to ADdreSs these objectives throuGh the UsE Of phYSiOlogiCally idENtIFIed NoCiCepToRS aNd anaTomIcally aNd physioloGicAlLy identified SUbSets of secoNd-oRder spinal inTerNeuronS. DEtaILed knOwlEdge oF the ceLLular mEchanisms UnDErlyinG The normAL BaLancE between excitatorY AnD Inhibitory inteRconneCtIOnS THat
, light and ultrastructura l microsco pical  an aly se s, a nd c omputational m o deli ng to address these ob jecti ve s  thr o ug h the  use of ph y s iol og ic all yi de ntifi ednocicep tors and a nat om ically and p h ys iologicall y i dentified su bse ts ofse con d -orde r s pinal  inter n eurons . Detaile dk nowled g e of th e ce llul ar mechanisms und e rl y ing the normal  balan ce be t w een  ex citatory a nd  inhi b itory i n te r c o nne c tions that
, light_and ultrastructural_microscopical analyses, and computational_modeling to_address_these objectives_through_the use of_physiologically identified nociceptors_and anatomically and physiologically_identified subsets of_second-order_spinal interneurons. Detailed knowledge of the cellular mechanisms underlying the normal balance between excitatory_and_inhibitory interconnections_that