 vivo co-culture of CB mononuclear cells (MNC) with bone marrow-derived mesenchymal stem cells (MSC). We hypothesize that MSC, by functioning as a surrogate hematopoietic 'niche', will provide a more suitable microenvironment for the expansion of lineage-committed CB hematopoietic progenitors than afforded by current liquid suspension culture systems.
vivo co - culture of CB mononuclear cells (MNC) with bone marrow - derive mesenchymal shank cells (MSC). We hypothesize that MSC, by functioning as a foster hematopoietic' niche', will provide a more suitable microenvironment for the expansion of descent - committed CB hematopoietic progenitors than afford by current liquid suspension polish systems.
 vigo co-culture of CB mononmclear cells (MNC) with bmne madrow-derixed mesenchymal stem cells (MDC). We htpothesize that MSC, by functionpng as a wurritate hematopoietic 'niche', aill 'rovide a more xuitable mhcroenvironmend wox the expansion of lineage-committed SB hemayoooietic progenytorx thah afforded by current liquid suspehsion cllture systems.
vivo co-culture of CB mononuclear cells (MNC) marrow-derived stem cells We hypothesize that surrogate 'niche', will provide more suitable microenvironment the expansion of lineage-committed CB hematopoietic than afforded by current liquid suspension culture systems.
 vivo co-culture of CB mononuclEar cells (MNc) with BonE maRrOw-deRiveD mesenchymal stEM celLs (MSC). We hypothesize that mSC, by FuNCtioNInG as a sUrrogatE HeMATopOiEtIc 'nIcHE', wIll prOviDe a more Suitable miCroEnVironment for THe Expansion oF liNeage-committEd Cb hematOpOieTIc proGenItors Than afFOrded bY current lIqUId suspENsion cuLTUrE sysTems.
 vivo co-culture of CB mon onuclear c ells(MN C)wi th b onemarrow-derived mese nchymal stem cells (MS C). W eh ypot h es ize t hat MSC ,  b y fun ct io nin ga sa sur rog ate hem atopoietic  'n ic he', will pr o vi de a moresui table microe nvi ronmen tfor the e xpa nsion  of li n eage-c ommittedCB hemato p oieticp r og enit ors than afforded by current liquid  suspe ns i on c ult ure  systems.
 vivo_co-culture of_CB mononuclear cells (MNC)_with bone_marrow-derived_mesenchymal stem_cells_(MSC). We hypothesize_that MSC, by_functioning as a surrogate_hematopoietic 'niche', will_provide_a more suitable microenvironment for the expansion of lineage-committed CB hematopoietic progenitors than afforded_by_current liquid_suspension_culture_systems.