 by comparing against 2-D monolayer and 3-D hydrogel cultures. We seek to define the mechanism of enhanced adipogenesis in the context of morphological cues (cell shape through the mmp14 pathway) regulating PPAR-?, a key effector of adipogenesis. (3) Determine the effects of multiple metabolic stresses (fatty
by comparing against 2 - D monolayer and 3 - D hydrogel cultures. We search to specify the mechanism of enhanced adipogenesis in the context of morphological cues (cellular telephone shape through the mmp14 pathway) regulating PPAR-? , a cardinal effecter of adipogenesis. (3) Determine the effects of multiple metabolic stresses (fatty
 by comparing against 2-D monulayer and 3-D hybeogel rulturea. We seey to define the mechanism of ebhanctb adipogenesis in thd context of morpyolojical cues (cell shape thvjugh bhe mk'14 pathway) regulsting PPAR-?, a key effectos uf adipogenesis. (3) Determine the effectf of muktlple metabolic strtssqs (fzntn
by comparing against 2-D monolayer and 3-D We to define mechanism of enhanced morphological (cell shape through mmp14 pathway) regulating a key effector of adipogenesis. (3) the effects of multiple metabolic stresses (fatty
 by comparing against 2-D monolaYer and 3-D hydRogel CulTurEs. we seEk to Define the mechaNIsm oF enhanced adipogenesis iN the cOnTExt oF MoRpholOgical cUEs (CELl sHaPe ThrOuGH tHe mmp14 PatHway) regUlating PPAr-?, a kEy Effector of adIPoGenesis. (3) DetErmIne the effectS of MultipLe MetABolic StrEsses (Fatty
 by comparing against 2-Dmonolayerand 3 -Dhyd ro gelcult ures. We seekt o de fine the mechanism ofenhan ce d  adi p og enesi s in th e  c o n tex tof  mo rp h ol ogica l c ues (ce ll shape t hro ug h the mmp14p at hway) regu lat ing PPAR-?,a k ey eff ec tor of ad ipo genes is. (3 )  Deter mine theef f ects o f  multip l e  m etab olic stresses (fa t ty 
 by_comparing against_2-D monolayer and 3-D_hydrogel cultures._We_seek to_define_the mechanism of_enhanced adipogenesis in_the context of morphological_cues (cell shape_through_the mmp14 pathway) regulating PPAR-?, a key effector of adipogenesis. (3) Determine the effects_of_multiple metabolic_stresses_(fatty