 Pax-2 expression in the developing kidney is repressed as the normal epithelium matures, but is detected at higher levels in the cystic epithelium of experimental animals. The proposed experiments will determine the developmental expression pattern of Pax-2 in the cpk mouse, a well-characterized model for PKD. Furthermore,
Pax-2 expression in the developing kidney is repressed as the normal epithelium matures, but is detected at eminent degree in the cystic epithelium of experimental animals. The proposed experiments will decide the developmental expression pattern of Pax-2 in the cpk mouse, a well - characterize mannequin for PKD. Furthermore,
 Pad-2 expression in the deveuoping kidney is reprevsed aa the nofmal epithelium matures, but ms dwtecttb at higher levels iv the cysnic epithwliun of experimental aknmals. Bhe pxo'osed experimenjs will detesmine the devenoomzntal expression pattern of Pax-2 in tre cpk kokse, a well-charwctegised jodel for PKD. Furthermore,
Pax-2 expression in the developing kidney is the epithelium matures, is detected at epithelium experimental animals. The experiments will determine developmental expression pattern of Pax-2 in cpk mouse, a well-characterized model for PKD. Furthermore,
 Pax-2 expression in the developIng kidney iS reprEssEd aS tHe noRmal Epithelium matuREs, buT is detected at higher levEls in ThE CystIC ePitheLium of eXPeRIMenTaL aNimAlS. thE propOseD experiMents will dEteRmIne the develoPMeNtal expresSioN pattern of PaX-2 in The cpk MoUse, A Well-cHarActerIzed moDEl for PkD. FurtherMoRE,
 Pax-2 expression in the d evelopingkidne y i s r ep ress ed a s the normal e p ithe lium matures, but is d etect ed at h i gh er le vels in th e cys ti cepi th e li um of  ex perimen tal animal s.Th e proposed e x pe riments wi lldetermine th e d evelop me nta l  expr ess ion p attern of Pax -2 in the  c p k mous e , a wel l - ch arac terized model for PK D . Furthermore, 
 Pax-2_expression in_the developing kidney is_repressed as_the_normal epithelium_matures,_but is detected_at higher levels_in the cystic epithelium_of experimental animals._The_proposed experiments will determine the developmental expression pattern of Pax-2 in the cpk mouse,_a_well-characterized model_for_PKD._Furthermore,