 When synthetic GnRH first became available for clinical study, there was not yet an adequate understanding of the physiology of GnRH secretion in the human to support its potential therapeutic application. As a result, early attempts at ovulation induction were unsuccessful. It was soon appreciated that an episodic mode of delivery was essential for normal pituitary
When synthetic GnRH first became available for clinical study, there be not so far an adequate understanding of the physiology of GnRH secretion in the human to support its likely therapeutic application. As a result, early attempt at ovulation induction were unsuccessful. It was soon appreciate that an episodic mode of delivery was substantive for normal pituitary
 Whfn synthetic GnRH first necame available for clmnical atudy, thdre was not yet an adequate nndeestaneing of the physiology of GnRH decretiob in rhe human vk suppovc its iotenciel therapeutic spplicatiot. As a result, aaflv attempts at ovulation induction wewe unsuvcfssful. It was foon wpprsbicted that an episodic mode of dslivery was essentiak for normal pituitary
When synthetic GnRH first became available for there not yet adequate understanding of in human to support potential therapeutic application. a result, early attempts at ovulation were unsuccessful. It was soon appreciated that an episodic mode of delivery was for normal pituitary
 When synthetic GnRH first becAme availabLe for CliNicAl StudY, theRe was not yet an aDEquaTe understanding of the phYsiolOgY Of Gnrh sEcretIon in thE HuMAN to SuPpOrt ItS PoTentiAl tHerapeuTic applicaTioN. AS a result, earlY AtTempts at ovUlaTion inductioN weRe unsuCcEssFUl. It wAs sOon apPreciaTEd that An episodiC mODe of deLIvery waS ESsEntiAl for normal pituitARy
 When synthetic GnRH first  became av ailab lefor  c lini calstudy, there w a s no t yet an adequate unde rstan di n g of th e phy siology of G nRH  s ec ret io n  i n the  hu man tosupport it s p ot ential thera p eu tic applic ati on. As a res ult , earl yatt e mptsatovula tion i n ductio n were un su c cessfu l . It wa s so on a ppreciated that a n  e p isodic mode of  deliv er y  w a s  es sen tial for n or mal p i tuitary 
 When_synthetic GnRH_first became available for_clinical study,_there_was not_yet_an adequate understanding_of the physiology_of GnRH secretion in_the human to_support_its potential therapeutic application. As a result, early attempts at ovulation induction were unsuccessful._It_was soon_appreciated_that_an episodic mode of delivery_was essential for normal pituitary