 place, without dissociation of the gp120 subunit, to create a functional form of the Env trimer. It might also be necessary to minimize the immunogenicity of the variable sequences. In preliminary studies on the creation of VLPs carrying HIV-1 Env proteins, we have begun to address the challenges outlined above. The preliminary
place, without dissociation of the gp120 subunit, to create a functional human body of the Env trimer. It might besides be necessary to minimize the immunogenicity of the variable sequence. In preliminary study on the creation of VLPs carrying HIV-1 Env protein, we have begun to address the challenges sketch above. The preliminary
 plwce, without dissociation of the gp120 subuuut, to rreate z functiunal form of the Env trimer. Mt mught qlso be necessary to mknimize tje immunigenmcity of the varmzble sequencea. In 'rxliminary studigs on the craation of VLPs cxrxying HIV-1 Env proteins, we have begun to addteds the challendes pttlihvd above. The preliminary
place, without dissociation of the gp120 subunit, a form of Env trimer. It minimize immunogenicity of the sequences. In preliminary on the creation of VLPs carrying Env proteins, we have begun to address the challenges outlined above. The preliminary
 place, without dissociation oF the gp120 subuNit, to CreAte A fUnctIonaL form of the Env tRImer. it might also be necessary To minImIZe thE ImMunogEnicity OF tHE VarIaBlE seQuENcEs. In pRelIminary Studies on tHe cReAtion of VLPs cARrYing HIV-1 Env ProTeins, we have bEguN to addReSs tHE chalLenGes ouTlined ABove. ThE preliminArY
 place, without dissociati on of thegp120  su bun it , to  cre ate a function a l fo rm of the Env trimer.It mi gh t  als o  b e nec essaryt om i nim iz ethe  i m mu nogen ici ty of t he variabl e s eq uences. In p r el iminary st udi es on the cr eat ion of  V LPs carry ing  HIV- 1 Envp rotein s, we hav eb egun t o  addres s th e ch allenges outlined ab o ve. The prelim inary
 place,_without dissociation_of the gp120 subunit,_to create_a_functional form_of_the Env trimer._It might also_be necessary to minimize_the immunogenicity of_the_variable sequences. In preliminary studies on the creation of VLPs carrying HIV-1 Env proteins,_we_have begun_to_address_the challenges outlined above. The_preliminary