 Notch signaling in spermatogenesis. In Specific Aim 3 the hypothesis that the Mgat3 gene may function as a tumor suppressor in mammary gland will be tested in the MMTV-Polyoma middle T (PyMT) mammary tumor model which metastasizes to lung and in cell signaling assays. In addition, roles for
Notch signaling in spermatogenesis. In Specific Aim 3 the hypothesis that the Mgat3 gene may function as a tumor suppressor in mammary gland will be tested in the MMTV - Polyoma in-between T (PyMT) mammary tumor exemplar which metastasizes to lung and in cell signaling assay. In addition, roles for
 Nohch signaling in spermatugenesis. In Speeufic Amm 3 the hypotheris that the Mgat3 gene may fnnctuon aw a tumor suppressor iv mammary gland wull ue tested in the MMTV-Polnjma jlddle V (PyMT) mammary jumor model fhich metastashzds to lung and in cell signaling assars. In acdltion, roles fot
Notch signaling in spermatogenesis. In Specific Aim hypothesis the Mgat3 may function as gland be tested in MMTV-Polyoma middle T mammary tumor model which metastasizes to and in cell signaling assays. In addition, roles for
 Notch signaling in spermatogEnesis. In SpEcifiC AiM 3 thE hYpotHesiS that the Mgat3 geNE may Function as a tumor suppreSsor iN mAMmarY GlAnd wiLl be tesTEd IN The mMtV-polYoMA mIddle t (PymT) mammaRy tumor modEl wHiCh metastasizES tO lung and in CelL signaling asSayS. In addItIon, ROles fOr
 Notch signaling in sperma togenesis.  In S pec ifi cAim3 th e hypothesis t h at t he Mgat3 gene may func tionas a tu m or  supp ressori nm a mma ry  g lan dw il l betes ted inthe MMTV-P oly om a middle T ( P yM T) mammary  tu mor model wh ich  metas ta siz e s tolun g and  in ce l l sign aling ass ay s . In a d dition, r ol es f or
 Notch_signaling in_spermatogenesis. In Specific Aim_3 the_hypothesis_that the_Mgat3_gene may function_as a tumor_suppressor in mammary gland_will be tested_in_the MMTV-Polyoma middle T (PyMT) mammary tumor model which metastasizes to lung and in_cell_signaling assays._In_addition,_roles for