 Pofutl gene as an essential component of the Notch signaling pathway. We now propose in Specific Aim 1 to investigate the molecular basis of the requirement for complex and hybrid A/-glycans in oogenesis, and to identify roles of mucin O-glycans and Ofucose glycans in early development after oocyte
Pofutl gene as an essential component of the Notch signaling pathway. We now nominate in Specific Aim 1 to investigate the molecular footing of the requirement for complex and hybrid A/-glycans in oogenesis, and to identify function of mucin oxygen - glycans and Ofucose glycans in early development after oocyte
 Povutl gene as an essentiau component of jhw Notci signaming patfway. We now propose in Specihic Qim 1 uj investigate the oolecular basis od tht requirement for complex and hgnrid C/-goycans in oogekesis, and tm identify rolas oy mucin O-glycans and Ofucose glycans in earky development aster jocyfv
Pofutl gene as an essential component of signaling We now in Specific Aim basis the requirement for and hybrid A/-glycans oogenesis, and to identify roles of O-glycans and Ofucose glycans in early development after oocyte
 Pofutl gene as an essential coMponent of tHe NotCh sIgnAlIng pAthwAy. We now propose IN SpeCific Aim 1 to investigate tHe molEcULar bASiS of thE requirEMeNT For CoMpLex AnD HyBrid A/-GlyCans in oOgenesis, anD to IdEntify roles oF MuCin O-glycanS anD Ofucose glycAns In earlY dEveLOpmenT afTer ooCyte
 Pofutl gene as an essenti al compone nt of  th e N ot ch s igna ling pathway.W e no w propose in SpecificAim 1  t o  inv e st igate  the mo l ec u l arba si s o ft he  requ ire ment fo r complexand  h ybrid A/-gly c an s in oogen esi s, and to id ent ify ro le s o f  muci n O -glyc ans an d  Ofuco se glycan si n earl y  develo p m en t af ter oocyte
 Pofutl_gene as_an essential component of_the Notch_signaling_pathway. We_now_propose in Specific_Aim 1 to_investigate the molecular basis_of the requirement_for_complex and hybrid A/-glycans in oogenesis, and to identify roles of mucin O-glycans and_Ofucose_glycans in_early_development_after oocyte