 (sphingolipids, fatty acids, cholesterol and cholesterol esters) reflect brain functioning and pathology, and may interact with ApoE genotype in the development of AD pathogenesis, warranting human studies. Clinical and epidemiological studies of short duration, while important, will not contribute to our understanding of the earliest phases of AD
(sphingolipids, fatty acids, cholesterol and cholesterol esters) reflect mind operation and pathology, and may interact with ApoE genotype in the development of AD pathogenesis, warranting human report. Clinical and epidemiologic studies of short duration, while important, will not lend to our understanding of the earliest phase of AD
 (spjingolipids, fatty acids, gholesterol and eyolestxrol esfers) refuect brain functioning and pethooogy, qnd may interact with XpoE genonype in tye dtvelopment of AD 'zthogencfis, swrrautmng human studigs. Clinical dnd epidemiolocizap studies of short duration, while iiportany, aill not contrybutt tj oud understanding of the earliest phzses of AD
(sphingolipids, fatty acids, cholesterol and cholesterol esters) functioning pathology, and interact with ApoE AD warranting human studies. and epidemiological studies short duration, while important, will not to our understanding of the earliest phases of AD
 (sphingolipids, fatty acids, chOlesterol aNd choLesTerOl EsteRs) reFlect brain funcTIoniNg and pathology, and may inTeracT wITh ApOe gEnotyPe in the DEvELOpmEnT oF AD PaTHoGenesIs, wArrantiNg human stuDieS. CLinical and epIDeMiological StuDies of short dUraTion, whIlE imPOrtanT, wiLl not ContriBUte to oUr understAnDIng of tHE earlieST PhAses Of AD
 (sphingolipids, fatty aci ds, choles terol  an d c ho lest erol  esters) refle c t br ain functioning and pa tholo gy ,  and ma y int eract w i th A poE  g en oty pe in  thedev elopmen t of AD pa tho ge nesis, warra n ti ng human s tud ies. Clinica l a nd epi de mio l ogica l s tudie s of s h ort du ration, w hi l e impo r tant, w i l lnotcontribute to our un d erstanding ofthe ea rl i es t pha ses  of AD
 (sphingolipids,_fatty acids,_cholesterol and cholesterol esters)_reflect brain_functioning_and pathology,_and_may interact with_ApoE genotype in_the development of AD_pathogenesis, warranting human_studies._Clinical and epidemiological studies of short duration, while important, will not contribute to our_understanding_of the_earliest_phases_of AD