 mouse. Utilizing the data obtained from these various investigational approaches, the designed chemotherapy programs will be clinically tested in patients. Enzymes containing mononuclear non-heme iron sites catalyze a diverse array of reactions that are significant to medicine and to the environment. This proposal describes plans to study three representatives of the largest,
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 mokse. Utilizing the data ontained from these varimus inbestigatkonal approaches, the designev chwmothtgapy programs will be clinicalpy testee in patients. Eiaymes containjkg mouoiuclear non-heme iron sitev catalyze a dhvdrde array of reactions that are signyficant tl medicine and to uhe envjgokment. This proposal describes plzns to vtudy three rrpresentatives of the largfst,
mouse. Utilizing the data obtained from these approaches, designed chemotherapy will be clinically mononuclear iron sites catalyze diverse array of that are significant to medicine and the environment. This proposal describes plans to study three representatives of the largest,
 mouse. Utilizing the data obtaIned from thEse vaRioUs iNvEstiGatiOnal approaches, THe deSigned chemotherapy progRams wIlL Be clINiCally Tested iN PaTIEntS. ENzYmeS cONtAininG moNonucleAr non-heme iRon SiTes catalyze a DIvErse array oF reActions that aRe sIgnifiCaNt tO MedicIne And to The envIRonmenT. This propOsAL descrIBes planS TO sTudy Three representatiVEs OF the largest,
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 mouse._Utilizing the_data obtained from these_various investigational_approaches,_the designed_chemotherapy_programs will be_clinically tested in_patients. Enzymes containing mononuclear_non-heme iron sites_catalyze_a diverse array of reactions that are significant to medicine and to the environment._This_proposal describes_plans_to_study three representatives of the_largest,