 MPO-ANCA immunoglobulin gene expression. We hypothesize that MPO-ANCA and PR3-ANCA expression is dependent on specific light and heavy chain usage and that both MPO and PR3 are selecting antigens in the maturation of this autoimmune response. We developed a technique to amplify message from single B cells,
MPO - ANCA immunoglobulin gene expression. We hypothesize that MPO - ANCA and PR3 - ANCA expression is dependent on specific inner light and dense chain usage and that both MPO and PR3 are selecting antigen in the maturation of this autoimmune response. We developed a proficiency to overstate message from single B cells,
 MPL-ANCA immunoglobulin gent expression. We hipithesive that MPO-ANCA and PR3-ANCA expression is de'endwnt ob specific light and hdavy chaij usage qnd uhat both MPO and PR3 are selectjkg ancijens in the matoration of tvis autoimmune rds'onse. We developed a technique to am[lify mrsdage from singje B sella,
MPO-ANCA immunoglobulin gene expression. We hypothesize that PR3-ANCA is dependent specific light and both and PR3 are antigens in the of this autoimmune response. We developed technique to amplify message from single B cells,
 MPO-ANCA immunoglobulin gene Expression. we hypOthEsiZe That mPO-AnCA and PR3-ANCA exPRessIon is dependent on specifIc ligHt ANd heAVy Chain Usage anD ThAT BotH MpO And pR3 ARe SelecTinG antigeNs in the matUraTiOn of this autoIMmUne responsE. We Developed a teChnIque to AmPliFY messAge From sIngle B CElls,
 MPO-ANCA immunoglobulin g ene expres sion.  We  hy po thes izethat MPO-ANCAa nd P R3-ANCA expression isdepen de n t on sp ecifi c light an d hea vy  c hai nu sa ge an d t hat bot h MPO andPR3  a re selecting an tigens inthe  maturationofthis a ut oim m une r esp onse.  We de v eloped  a techni qu e  to am p lify me s s ag e fr om single B cells , 
 MPO-ANCA_immunoglobulin gene_expression. We hypothesize that_MPO-ANCA and_PR3-ANCA_expression is_dependent_on specific light_and heavy chain_usage and that both_MPO and PR3_are_selecting antigens in the maturation of this autoimmune response. We developed a technique to_amplify_message from_single_B_cells,