 microscopic analysis, including partial denaturation and heteroduplex techniques, and cleavage of specific circular DNA classes with site-specific restriction endonucleases in order to determine the relationships between these molecules. DNA-DNA hybridization will also be employed as will sedimentation velocity procedures for characterization of these elements. Specific inhibitors will be employed
microscopic analysis, including partial denaturation and heteroduplex techniques, and cleavage of specific round deoxyribonucleic acid class with site - specific limitation endonucleases in club to determine the kinship between these atom. DNA - DNA hybridization will besides be use as will sedimentation velocity procedure for characterization of these elements. Specific inhibitor will be employed
 mifroscopic analysis, incluaing partial deuqturatmon and heterodjplex techniques, and cleavagx of specufic circular DNA clasres with dite-specufic eestrictioi endonugjeassd in irder to deterkine the ralationships batdezn these molecules. DNA-DNA hybridizatyon wilk wlso be employgd as rill sedimentation velocity procedures for cheracterization pf these elements. Specific inhlbitors will be emoloyed
microscopic analysis, including partial denaturation and heteroduplex cleavage specific circular classes with site-specific determine relationships between these DNA-DNA hybridization will be employed as will sedimentation velocity for characterization of these elements. Specific inhibitors will be employed
 microscopic analysis, includIng partial DenatUraTioN aNd heTeroDuplex techniquES, and Cleavage of specific circUlar DnA CLassES wIth siTe-speciFIc REStrIcTiOn eNdONuCleasEs iN order tO determine The ReLationships bETwEen these moLecUles. DNA-DNA hyBriDizatiOn WilL Also bE emPloyeD as wilL SedimeNtation veLoCIty proCEdures fOR ChAracTerization of these ELeMEnts. Specific inHibitoRs WIlL BE emPloYed
 microscopic analysis, inc luding par tialden atu ra tion  and  heteroduplext echn iques, and cleavage of  spec if i c ci r cu lar D NA clas s es w ith  s it e-s pe c if ic re str ictionendonuclea ses  i n order to d e te rmine therel ationships b etw een th es e m o lecul es.  DNA- DNA hy b ridiza tion will  a l so bee mployed a swill  sedimentation ve l oc i ty proceduresfor ch ar a ct e r iza tio n of these  e lemen t s. Spec i fi c i nhi b itors will be  employed
 microscopic_analysis, including_partial denaturation and heteroduplex_techniques, and_cleavage_of specific_circular_DNA classes with_site-specific restriction endonucleases_in order to determine_the relationships between_these_molecules. DNA-DNA hybridization will also be employed as will sedimentation velocity procedures for characterization_of_these elements._Specific_inhibitors_will be employed