 rarely progresses to blast crisis; rather, mortality is due to extramedullary tumor cell expansion leading to organ failure, respiratory failure, bleeding, or infection. Notably, following allogeneic stem cell transplant, 50% of children succumb to leukemia relapse. This relapse rate in JMML is substantially higher than that of
rarely progresses to blast crisis; rather, mortality is ascribable to extramedullary tumor cellular telephone expansion lead to organ failure, respiratory bankruptcy, bleeding, or infection. Notably, stick to allogeneic stem cell graft, 50% of child succumb to leukemia backsliding. This backsliding rate in JMML is substantially high than that of
 ragely progresses to blast crisis; rather, mortalivy is dhe to exgramedullary tumor cell expaisiob leaeing to organ failure, fespiratogy failurw, blteding, or infection. Notably, folmlwiny ellogeneic stem cell tranvplant, 50% of chindfeu succumb to leukemia relapse. This rqlapse tahe in JMML is fubsuaneialmj migher than that of
rarely progresses to blast crisis; rather, mortality to tumor cell leading to organ infection. following allogeneic stem transplant, 50% of succumb to leukemia relapse. This relapse in JMML is substantially higher than that of
 rarely progresses to blast crIsis; rather, MortaLitY is DuE to eXtraMedullary tumor CEll eXpansion leading to organ FailuRe, REspiRAtOry faIlure, blEEdING, or InFeCtiOn. nOtAbly, fOllOwing alLogeneic stEm cElL transplant, 50% oF ChIldren succUmb To leukemia reLapSe. This ReLapSE rate In JmML is SubstaNTially Higher thaN tHAt of
 rarely progresses to blas t crisis;rathe r,mor ta lity  isdue to extrame d ulla ry tumor cell expansio n lea di n g to or gan f ailure, re s p ira to ry  fa il u re , ble edi ng, orinfection.  No ta bly, followi n gallogeneic  st em cell tran spl ant, 5 0%  of child ren  succ umb to leukem ia relaps e. This r e lapse r a t ein J MML is substantia l ly higher than th at of
 rarely_progresses to_blast crisis; rather, mortality_is due_to_extramedullary tumor_cell_expansion leading to_organ failure, respiratory_failure, bleeding, or infection._Notably, following allogeneic_stem_cell transplant, 50% of children succumb to leukemia relapse. This relapse rate in JMML_is_substantially higher_than_that_of