 bleeding disorder known as Bernard-Soulier syndrome. The interaction of platelets with vWF through the GP Ib-IX receptor has also been shown to be relevant for the development of pathological platelet thrombi responsible for vascular occlusion. Therefore, studies on the structure and function of GP Ib-IX are relevant for understanding the pathogenesis
bleeding disorder known as Bernard - Soulier syndrome. The interaction of platelets with vWF through the GP Ib - nine sense organ has besides been shown to be relevant for the development of pathological platelet thrombus responsible for vascular occlusion. Therefore, study on the structure and function of GP Ib - IX are relevant for understand the pathogenesis
 blfeding disorder known as Bernard-Soulier syndroke. The interacgion of platelets with vWF tirouth tht GP Ib-IX receptor fas also heen shoqn ti be relevaif for tmz devspopmznv of pathologicsl plateled thrombi respmnriyle for vascular occlusion. Therefore, studiex ln the structute anc fundniin of GP Ib-IX are relevant fod undervtanding the lathogenesis
bleeding disorder known as Bernard-Soulier syndrome. The platelets vWF through GP Ib-IX receptor be for the development pathological platelet thrombi for vascular occlusion. Therefore, studies on structure and function of GP Ib-IX are relevant for understanding the pathogenesis
 bleeding disorder known as BeRnard-SouliEr synDroMe. THe InteRactIon of platelets WIth vwF through the GP Ib-IX recePtor hAs ALso bEEn Shown To be relEVaNT For ThE dEveLoPMeNt of pAthOlogicaL platelet tHroMbI responsible FOr Vascular ocCluSion. ThereforE, stUdies oN tHe sTRuctuRe aNd funCtion oF gP Ib-IX Are relevaNt FOr undeRStandinG THe PathOgenesis
 bleeding disorder known a s Bernard- Souli ersyn dr ome.  The  interaction o f  pla telets with vWF throug h the  G P  Ib- I Xrecep tor has al s o  be en  s how nt obe re lev ant for  the devel opm en t of patholo g ic al platele t t hrombi respo nsi ble fo rvas c ularocc lusio n. The r efore,  studieson the st r ucturea n dfunc tion of GP Ib-IXa re relevant for u nderst an d in g the  pa thogenesis 
 bleeding_disorder known_as Bernard-Soulier syndrome. The_interaction of_platelets_with vWF_through_the GP Ib-IX_receptor has also_been shown to be_relevant for the_development_of pathological platelet thrombi responsible for vascular occlusion. Therefore, studies on the structure and_function_of GP_Ib-IX_are_relevant for understanding the pathogenesis