 of two subunits, with expression of the IL-12 receptor beta 2 chain (IL-12RB2) dictating a high affinity IL-12 receptor complex. Signaling through this high affinity IL-12 receptor controls the development of TH1 lymphocytes and the maintenance of this phenotype, while limiting lineage commitment to the TH2
of two subunits, with expression of the IL-12 receptor beta 2 chain (IL-12RB2) dictate a eminent affinity IL-12 receptor complex. Signaling through this gamey affinity IL-12 receptor controls the exploitation of TH1 lymphocyte and the maintenance of this phenotype, while limiting lineage commitment to the TH2
 of two subunits, with exprersion of the IL-12 receptmr betz 2 chain (IL-12RB2) dictating a high affinmty UL-12 rexeptor complex. Signalivg througj this hugh effinity IL-12 rece'for conbxols fme dereoopment of TH1 kymphocytev and the maindevauce of this phenotype, while limiting lineagr fommitment to jhe TN2
of two subunits, with expression of the beta chain (IL-12RB2) a high affinity this affinity IL-12 receptor the development of lymphocytes and the maintenance of this while limiting lineage commitment to the TH2
 of two subunits, with expressiOn of the IL-12 rEceptOr bEta 2 ChAin (Il-12RB2) dIctating a high aFFiniTy IL-12 receptor complex. SigNalinG tHRougH ThIs higH affiniTY Il-12 REcePtOr ConTrOLs The deVelOpment oF TH1 lymphocYteS aNd the maintenANcE of this pheNotYpe, while limiTinG lineaGe ComMItmenT to The TH2
 of two subunits, with exp ression of  theIL- 12re cept or b eta 2 chain (I L -12R B2) dictating a high a ffini ty IL-1 2  r ecept or comp l ex . Sig na li ngth r ou gh th ishigh af finity IL- 12re ceptor contr o ls  the devel opm ent of TH1 l ymp hocyte sand the m ain tenan ce oft his ph enotype,wh i le lim i ting li n e ag e co mmitment to the T H 2
 of_two subunits,_with expression of the_IL-12 receptor_beta_2 chain_(IL-12RB2)_dictating a high_affinity IL-12 receptor_complex. Signaling through this_high affinity IL-12_receptor_controls the development of TH1 lymphocytes and the maintenance of this phenotype, while limiting_lineage_commitment to_the_TH2