. These ongoing studies give rise to an overarching hypothesis to be tested in four interrelated sub-projects in this SCR requiring a highly integrated approach. The SCR overall novel hypothesis addressed is: Periodontal disease (oral inflammation and tissue injury), certain microbes, surgical anesthesia, and other widely used drugs impact recently uncovered
. These ongoing studies give rise to an overarching hypothesis to be quiz in four interconnected sub - projects in this SCR command a highly desegregate approach. The SCR overall novel guess addressed is: Periodontal disease (oral inflammation and tissue wound), sealed microbes, surgical anesthesia, and other wide used drugs shock recently uncover
. Thfse ongoing studies give rise to an ovetaeching hypotgesis to be tested in four interrelaved wub-prijects in this SCR reqjiring a jighly ibtegcated approach. Tis SCR oyzrall kovel iypothesis addrgssed is: Perhodontal diseave (oxal inflammation and tissue injury), cqrtain kifrobes, surgicaj antstresiz, and other widely used drugs impadt receitly uncovered
. These ongoing studies give rise to hypothesis be tested four interrelated sub-projects highly approach. The SCR novel hypothesis addressed Periodontal disease (oral inflammation and tissue certain microbes, surgical anesthesia, and other widely used drugs impact recently uncovered
. These ongoing studies give riSe to an overArchiNg hYpoThEsis To be Tested in four inTErreLated sub-projects in this sCR reQuIRing A HiGhly iNtegratED aPPRoaCh. thE SCr oVErAll noVel HypotheSis addressEd iS: PEriodontal diSEaSe (oral inflAmmAtion and tissUe iNjury), cErTaiN MicroBes, SurgiCal aneSThesia, And other wIdELy used DRugs impACT rEcenTly uncovered
. These ongoing studies gi ve rise to  an o ver arc hi ng h ypot hesis to be te s tedin four interrelated s ub-pr oj e ctsi nthisSCR req u ir i n g a  h ig hly  i n te grate d a pproach . The SCRove ra ll novel hyp o th esis addre sse d is: Period ont al dis ea se( oralinf lamma tion a n d tiss ue injury ), certai n  microb e s ,surg ical anesthesia,a nd other widely u sed dr ug s  i m p act  re cently unc ov ered
. These_ongoing studies_give rise to an_overarching hypothesis_to_be tested_in_four interrelated sub-projects_in this SCR_requiring a highly integrated_approach. The SCR_overall_novel hypothesis addressed is: Periodontal disease (oral inflammation and tissue injury), certain microbes, surgical_anesthesia,_and other_widely_used_drugs impact recently uncovered