 capability do not exist. We propose to develop these novel tools by applying newly developed cell-based protein-protein interaction LinkLight assay technology. The assays can measure specific subcellular ERK activation signaling pathways. ERK signaling pathways are implicated in LTP, memory, learning, mood stabilization etc. Therefore, developing these tools for identifying compounds
capability do not exist. We propose to develop these novel tools by apply newly modernize cell - based protein - protein interaction LinkLight assay engineering. The assays can measure specific subcellular ERK activation sign pathways. ERK signaling nerve pathway are implicated in LTP, memory, learning, climate stabilization etc. Therefore, developing these instrument for identify compounds
 caoability do not exist. We propose to devglip theve novsl tools by applying newly developed cwll-bawed protein-protein intdraction PinkLighr aswqy technology. The assays gan mzawure specific xubcellulas ERK activatimn sngnaling pathways. ERK signaling pathrays arr lmplicated in JTP, kqmorg, learning, mood stabilization etc. Fherefoge, developing thexe tools for identifying clmpoknds
capability do not exist. We propose to novel by applying developed cell-based protein-protein assays measure specific subcellular activation signaling pathways. signaling pathways are implicated in LTP, learning, mood stabilization etc. Therefore, developing these tools for identifying compounds
 capability do not exist. We proPose to deveLop thEse NovEl ToolS by aPplying newly deVElopEd cell-based protein-protEin inTeRActiON LInkLiGht assaY TeCHNolOgY. THe aSsAYs Can meAsuRe speciFic subcellUlaR ErK activation SIgNaling pathWayS. ERK signalinG paThways ArE imPLicatEd iN LTP, mEmory, lEArning, Mood stabiLiZAtion eTC. TherefORE, dEvelOping these tools foR IdENtifying compouNds
 capability do not exist.We propose  to d eve lop  t hese  nov el tools by ap p lyin g newly developed cell -base dp rote i n- prote in inte r ac t i onLi nk Lig ht as say t ech nology.  The assay s c an  measure spe c if ic subcell ula r ERK activa tio n sign al ing pathw ays . ERK  signa l ing pa thways ar ei mplica t ed in L T P ,memo ry, learning, moo d  s t abilization et c. The re f or e ,  de vel oping thes etools for ide n ti f y i ngc ompounds
 capability_do not_exist. We propose to_develop these_novel_tools by_applying_newly developed cell-based_protein-protein interaction LinkLight_assay technology. The assays_can measure specific_subcellular_ERK activation signaling pathways. ERK signaling pathways are implicated in LTP, memory, learning, mood_stabilization_etc. Therefore,_developing_these_tools for identifying compounds