 injury. We will use one of the most inflammatory of all CNS disease models, the multiple sclerosis model, experimental autoimmune encephalomyelitis (EAE), to show applicability of this approach to a variety of neurological diseases. We will employ mice which differ in the complement of sex chromosomes (XX vs. XY), while having
injury. We will use one of the most inflammatory of all CNS disease models, the multiple sclerosis exemplar, experimental autoimmune encephalomyelitis (EAE), to picture applicability of this approach to a variety of neurological diseases. We will hire mice which differ in the complement of sexual activity chromosomes (XX vs. XY), while having
 inuury. We will use one of uhe most inflammajoey of ell CNS disease models, the multiple sclerosms midel, tqperimental autoimmund encephapomyelitus (EEE), to show applirzbility of thjd ap'riach to a varigty of neuronogical diseasas. Wz will employ mice which differ in tre compkelent of sex chtomospies (SQ ys. XY), while having
injury. We will use one of the of CNS disease the multiple sclerosis to applicability of this to a variety neurological diseases. We will employ mice differ in the complement of sex chromosomes (XX vs. XY), while having
 injury. We will use one of the moSt inflammaTory oF alL CNs dIseaSe moDels, the multiplE ScleRosis model, experimental AutoiMmUNe enCEpHalomYelitis (eaE), TO ShoW aPpLicAbILiTy of tHis ApproacH to a varietY of NeUrological diSEaSes. We will eMplOy mice which dIffEr in thE cOmpLEment Of sEx chrOmosomES (XX vs. Xy), while havInG
 injury. We will use one o f the most  infl amm ato ry  ofallCNS disease mo d els,  the multiple sclerosi s mod el ,  exp e ri menta l autoi m mu n e  en ce ph alo my e li tis ( EAE ), to s how applic abi li ty of this a p pr oach to avar iety of neur olo gicaldi sea s es. W e w ill e mploym ice wh ich diffe ri n thec ompleme n t  o f se x chromosomes (XX vs .  XY), while ha ving
 injury._We will_use one of the_most inflammatory_of_all CNS_disease_models, the multiple_sclerosis model, experimental_autoimmune encephalomyelitis (EAE), to_show applicability of_this_approach to a variety of neurological diseases. We will employ mice which differ in_the_complement of_sex_chromosomes_(XX vs. XY), while having