 human monoclonal antibody A12. This aim will use the 27 unique human prostate cancer xenografts available in the Biospecimen Core as well as our preclinical finding of the significant synergy between castration and IGF-IR inhibition. Aim 2. Analysis of the functional interactions of the AR on IGF-IR gene expression as a
human monoclonal antibody A12. This aim will use the 27 unique human prostate gland cancer heterograft available in the Biospecimen Core equally well as our preclinical finding of the significant synergy between castration and IGF - IR prohibition. Aim 2. Analysis of the functional interaction of the AR on IGF - IR gene expression as a
 hulan monoclonal antibody X12. This aim will use thx 27 uniqhe human prostate cancer xenografts evaioable in the Biospecimen Cofe as welp as our prerlinical finding of the signifjgant vbnergy between gastration dnd IGF-IR inhitigiln. Aim 2. Analysis of the functional ynteracyilns of the AR jn IBS-IR fvnt expression as a
human monoclonal antibody A12. This aim will 27 human prostate xenografts available in as preclinical finding of significant synergy between and IGF-IR inhibition. Aim 2. Analysis the functional interactions of the AR on IGF-IR gene expression as a
 human monoclonal antibody A12. THis aim will Use thE 27 unIquE hUman ProsTate cancer xenoGRaftS available in the BiospecImen COrE As weLL aS our pRecliniCAl FINdiNg Of The SiGNiFicanT syNergy beTween castrAtiOn And IGF-IR inhiBItIon. Aim 2. AnalYsiS of the functiOnaL interAcTioNS of thE AR On IGF-iR gene EXpressIon as a
 human monoclonal antibody  A12. This  aimwil l u se  the  27unique human p r osta te cancer xenografts a vaila bl e  int he  Bios pecimen Co r e  as  w el l a so ur  prec lin ical fi nding of t hesi gnificant sy n er gy between  ca stration and  IG F-IR i nh ibi t ion.Aim  2. A nalysi s  of th e functio na l  inter a ctionso f  t he A R on IGF-IR genee xp r ession as a
 human_monoclonal antibody_A12. This aim will_use the_27_unique human_prostate_cancer xenografts available_in the Biospecimen_Core as well as_our preclinical finding_of_the significant synergy between castration and IGF-IR inhibition. Aim 2. Analysis of the functional_interactions_of the_AR_on_IGF-IR gene expression as a