 expression during abortive infection by SV40, and 3) the relationship between viral mediated control of DHFR synthesis and the control by cell cycle, serum growth factors, and cyclic nucleotides. An important feature of the proposed research is the use of methotrexate resistant cell lines in which one of the viral induced enzymes,
expression during abortive infection by SV40, and 3) the relationship between viral mediated restraint of DHFR deduction and the control by cell hertz, serum emergence factors, and cyclic nucleotides. An significant feature of the proposed inquiry is the habit of methotrexate resistant cellular telephone lines in which one of the viral induced enzymes,
 exoression during abortive infection by SR40, and 3) vhe relztionshio between viral mediated convrol of DYFR synthesis and the zontrol bj cell cyxle, wwrum growti factors, and dnclic iucleotides. An lmportant faature of the [ruplsed research is the use of methotrqxate rrslstant cell liges pn whidh one of the viral induced enzymea,
expression during abortive infection by SV40, and relationship viral mediated of DHFR synthesis cycle, growth factors, and nucleotides. An important of the proposed research is the of methotrexate resistant cell lines in which one of the viral induced enzymes,
 expression during abortive iNfection by sV40, and 3) The RelAtIonsHip bEtween viral medIAted Control of DHFR synthesis And thE cONtroL By Cell cYcle, serUM gROWth FaCtOrs, AnD CyClic nUclEotides. an importanT feAtUre of the propOSeD research iS thE use of methotRexAte resIsTanT Cell lIneS in whIch one OF the viRal induceD eNZymes,
 expression during abortiv e infectio n bySV4 0,an d 3)  the  relationshipb etwe en viral mediated cont rol o fD HFRs yn thesi s and t h ec o ntr ol  b y c el l  c ycle,  se rum gro wth factor s,an d cyclic nuc l eo tides. Animp ortant featu reof the  p rop o sed r ese archis the use of  methotre xa t e resi s tant ce l l  l ines  in which one oft he viral inducedenzyme s, 
 expression_during abortive_infection by SV40, and_3) the_relationship_between viral_mediated_control of DHFR_synthesis and the_control by cell cycle,_serum growth factors,_and_cyclic nucleotides. An important feature of the proposed research is the use of methotrexate_resistant_cell lines_in_which_one of the viral induced_enzymes,