 that the rate of increase in PIB retention in individual subjects will be of larger magnitude and be detectable earlier than the rate of decrease in hippocampal volume or cerebral metabolic rate. The volume and electrolyte composition of saliva are dependent on the coordinated activity of ion transport proteins including multiple Na+-dependent mechanisms. Acinar cells employ a combination
that the rate of increase in PIB retention in individual subjects will be of large order of magnitude and be detectable earlier than the rate of decrease in hippocampal bulk or cerebral metabolic pace. The volume and electrolyte composition of saliva are dependent on the coordinated action of ion transport proteins include multiple Na+-dependent mechanisms. Acinar cells hire a combination
 thwt the rate of increase ln PIB retention in indmvidual subjectr will be of larger magnitudx ane be eetectable earlier thav the ratv of decrwase un hippocampal volmie od cerzbcal metabolic rste. The vonume and electsouyce composition of saliva are dependegt on tne coordinated astivptr of pok transport proteins including mhltiple Na+-dependent kechanisms. Acinar cells emoloy a combination
that the rate of increase in PIB individual will be larger magnitude and rate decrease in hippocampal or cerebral metabolic The volume and electrolyte composition of are dependent on the coordinated activity of ion transport proteins including multiple Na+-dependent Acinar cells employ a combination
 that the rate of increase in PIb retention In indIviDuaL sUbjeCts wIll be of larger mAGnitUde and be detectable earlIer thAn THe raTE oF decrEase in hIPpOCAmpAl VoLumE oR CeRebraL meTabolic Rate. The volUme AnD electrolyte COmPosition of SalIva are dependEnt On the cOoRdiNAted aCtiVity oF ion trANsport Proteins iNcLUding mULtiple NA+-DEpEndeNt mechanisms. AcinaR CeLLs employ a combiNation
 that the rate of increase  in PIB re tenti oninin divi dual  subjects will be o f larger magnitude and  be d et e ctab l eearli er than th e rat eof  de cr e as e inhip pocampa l volume o r c er ebral metabo l ic  rate. The  vo lume and ele ctr olyteco mpo s ition  of  sali va are depend ent on th ec oordin a ted act i v it y of  ion transport pr o te i ns including m ultipl eN a+ - d epe nde nt mechani sm s. Ac i nar cel l se m p loy a combination 
 that_the rate_of increase in PIB_retention in_individual_subjects will_be_of larger magnitude_and be detectable_earlier than the rate_of decrease in_hippocampal_volume or cerebral metabolic rate. The volume and electrolyte composition of saliva are dependent_on_the coordinated_activity_of_ion transport proteins including multiple_Na+-dependent mechanisms. Acinar cells employ_a combination