 congenic for the H-2b genotype derived from strain C57L/J. These mice have been shown in our laboratory to have delayed and reduced leukemia incidence with respect to AKR/J and preliminary evidence incicates that they also have an altered immune responsiveness. This study is designed to confirm and expand upon these
congenic for the H-2b genotype derived from strain C57L / J. These mice have been shown in our laboratory to have stay and reduce leukemia incidence with respect to AKR / J and preliminary evidence incicates that they also have an adapted immune responsiveness. This study is designed to confirm and expand upon these
 cojgenic for the H-2b genotyke derived from sjrqin C57L/O. These mice haxe been shown in our laboratlrt to yave delayed and reducdd leukempa incidebce xith respect to EIR/J and prelijlnary xvidence incicajes that thef also have an autzred immune responsiveness. This studr is dexihned to confiri anc expznd upon these
congenic for the H-2b genotype derived from These have been in our laboratory leukemia with respect to and preliminary evidence that they also have an altered responsiveness. This study is designed to confirm and expand upon these
 congenic for the H-2b genotype dErived from StraiN C57L/j. ThEsE micE havE been shown in ouR LaboRatory to have delayed and ReducEd LEukeMIa IncidEnce witH ReSPEct To aKr/J aNd PReLiminAry EvidencE incicates ThaT tHey also have aN AlTered immunE reSponsiveness. thiS study Is DesIGned tO coNfirm And expANd upon These
 congenic for the H-2b gen otype deri ved f rom  st ra in C 57L/ J. These miceh avebeen shown in our labo rator yt o ha v edelay ed andr ed u c edle uk emi ai nc idenc e w ith res pect to AK R/J  a nd prelimina r yevidence i nci cates that t hey  alsoha vea n alt ere d imm une re s ponsiv eness. Th is studyi s desig n e dto c onfirm and expand up o n these
 congenic_for the_H-2b genotype derived from_strain C57L/J._These_mice have_been_shown in our_laboratory to have_delayed and reduced leukemia_incidence with respect_to_AKR/J and preliminary evidence incicates that they also have an altered immune responsiveness. This_study_is designed_to_confirm_and expand upon these