 CD45RB isoform. By using T isolated from OVA-TCR Tg mice, we will be able to control exposure of the separate populations to antigen after adoptive transfer to SCID mice. This will allow us to dissect the earliest antigenic responses of these two populations during disease progression or prevention. In parallel
CD45RB isoform. By using T isolated from OVA - TCR Tg mice, we will be able to see vulnerability of the separate populations to antigen after adoptive transportation to SCID mice. This will allow us to analyze the early antigenic responses of these two population during disease progression or prevention. In parallel
 CD45GB isoform. By using T isulated from OVA-JCE Tg mmce, we sill be xble to control exposure of vhe weparqte populations to antkgen afteg adoptivw trensfer to SCID mmde. This will zplow ns to dissect tme earliest antigenic res[ovszs of these two populations during dysease lrlgression or ptevenuiog. In iavallel
CD45RB isoform. By using T isolated from mice, will be to control exposure antigen adoptive transfer to mice. This will us to dissect the earliest antigenic of these two populations during disease progression or prevention. In parallel
 CD45RB isoform. By using T isolatEd from OVA-TcR Tg mIce, We wIlL be aBle tO control exposuRE of tHe separate populations tO antiGeN AfteR AdOptivE transfER tO scID MiCe. thiS wILl Allow Us tO dissecT the earlieSt aNtIgenic responSEs Of these two PopUlations duriNg dIsease PrOgrESsion Or pRevenTion. In PAralleL
 CD45RB isoform. By usingT isolated  from  OV A-T CR  Tgmice , we will be a b le t o control exposure ofthe s ep a rate po pulat ions to an t i gen  a ft erad o pt ive t ran sfer to  SCID mice . T hi s will allow us  to dissec t t he earliestant igenic  r esp o nsesofthese  two p o pulati ons durin gd isease progres s i on  orprevention. In pa r al l el
 CD45RB_isoform. By_using T isolated from_OVA-TCR Tg_mice,_we will_be_able to control_exposure of the_separate populations to antigen_after adoptive transfer_to_SCID mice. This will allow us to dissect the earliest antigenic responses of these_two_populations during_disease_progression_or prevention. In parallel