 basis for the development of TMEV-induced demyelinating disease, and defined a critical role for MHC class II-restricted, virus-specific DTH responses in the demyelinating process. We have also demonstrated that chronic CNS demyelination can occur in the apparent absence of neuroantigen-specific autoimmune responses
basis for the development of TMEV - induced demyelinating disease, and defined a critical function for MHC course II - restricted, virus - specific DTH responses in the demyelinating procedure. We have besides demonstrated that chronic CNS demyelination can occur in the apparent absence of neuroantigen - specific autoimmune response
 badis for the development uf TMEV-induced bwmyeliiating sisease, xnd defined a critical role hor NHC coass II-restricted, virur-specific DTH responsts in the demyeliizting pvjcesa. We kate also demonsttated that cvronic CNS demfeuiuation can occur in the apparent absqnce of nfuroantigen-spesifib wutojmmune responses
basis for the development of TMEV-induced demyelinating defined critical role MHC class II-restricted, demyelinating We have also that chronic CNS can occur in the apparent absence neuroantigen-specific autoimmune responses
 basis for the development of TmEV-induced DemyeLinAtiNg DiseAse, aNd defined a critICal rOle for MHC class II-restriCted, vIrUS-speCIfIc DTH ResponsES iN THe dEmYeLinAtINg ProceSs. WE have alSo demonstrAteD tHat chronic CNs DeMyelinatioN caN occur in the aPpaRent abSeNce OF neurOanTigen-SpecifIC autoiMmune respOnSEs
 basis for the development  of TMEV-i nduce d d emy el inat ingdisease, and d e fine d a critical role forMHC c la s s II - re stric ted, vi r us - s pec if ic  DT Hr es ponse s i n the d emyelinati ngpr ocess. We ha v ealso demon str ated that ch ron ic CNS  d emy e linat ion  canoccuri n theapparentab s ence o f  neuroa n t ig en-s pecific autoimmun e  r e sponses
 basis_for the_development of TMEV-induced demyelinating_disease, and_defined_a critical_role_for MHC class_II-restricted, virus-specific DTH_responses in the demyelinating_process. We have_also_demonstrated that chronic CNS demyelination can occur in the apparent absence of neuroantigen-specific autoimmune_responses