 could improve the health care for millions of patients. PROJECT SUMMARY/ABSTRACT Chemoresistant metastatic disease presents the most serious threat to cancer patients despite the increased arsenal of targeted therapeutic options available to clinicians. While intense study into late-stage cancer progression has revealed a number of mechanisms that contribute to chemoresistance,
could improve the health care for millions of patients. PROJECT SUMMARY / ABSTRACT Chemoresistant metastatic disease stage the about serious threat to cancer patient despite the increase arsenal of targeted curative options available to clinicians. While intense survey into late - stage cancer progress has revealed a number of mechanism that contribute to chemoresistance,
 cokld improve the health cxre for millions of pavients. LROJECT RUMMARY/ABSTRACT Chemoresistait mwtastqtic disease presents ghe most derious rhreet to cancer patmsnts despite fme inerxased arsenal on targeted dherapeutic opdiund available to clinicians. While intqnse stidj into late-stade csgcer irigression has revealed a numbsr of mtchanisms that conyribute to chemoresistance,
could improve the health care for millions PROJECT Chemoresistant metastatic presents the most despite increased arsenal of therapeutic options available clinicians. While intense study into late-stage progression has revealed a number of mechanisms that contribute to chemoresistance,
 could improve the health care For millionS of paTieNts. pRoJECt SUMmARY/ABSTRACT ChEMoreSistant metastatic diseaSe preSeNTs thE MoSt serIous thrEAt TO CanCeR pAtiEnTS dEspitE thE increaSed arsenal Of tArGeted therapeUTiC options avAilAble to clinicIanS. While InTenSE studY inTo latE-stage CAncer pRogressioN hAS reveaLEd a numbER Of MechAnisms that contribUTe TO chemoresistanCe,
 could improve the healthcare for m illio nsofpa tien ts.PROJECT SUMMAR Y /ABS TRACT Chemoresistant m etast at i c di s ea se pr esentst he m ost  s er iou st hr eat t o c ancer p atients de spi te  the increas e darsenal of  ta rgeted thera peu tic op ti ons avail abl e toclinic i ans. W hile inte ns e  study into la t e -s tage  cancer progressi o nh as revealed anumber  o f  m e c han ism s that con tr ibute to chem o re s i s tan c e,
 could_improve the_health care for millions_of patients._PROJECT_SUMMARY/ABSTRACT Chemoresistant_metastatic_disease presents the_most serious threat_to cancer patients despite_the increased arsenal_of_targeted therapeutic options available to clinicians. While intense study into late-stage cancer progression has_revealed_a number_of_mechanisms_that contribute to chemoresistance,