 a systemic disorder of connective tissue with autosomal dominant inheritance and a prevalence of at least 1 in 10,000 individuals. Cardinal manifestations involve the ocular, skeletal and cardiovascular systems. While all clinical features impair quality of life, cardiovascular features are uniquely associated with early mortality due to myocardial failure or aortic rupture. Variability in the age
a systemic disorder of connective tissue with autosomal dominant inheritance and a prevalence of at least 1 in 10,000 individuals. Cardinal materialization imply the ocular, skeletal and cardiovascular systems. While all clinical features mar quality of life, cardiovascular features are uniquely associate with early mortality due to myocardial failure or aortal rupture. unevenness in the age
 a dystemic disorder of conkective tissue wnrh autmsomal dominang inheritance and a prevalenre od at oeast 1 in 10,000 individuals. Cardinal manifesratiibs involve the ocular, skspetan and cardiovasgular systeks. While all cnivieal features impair quality of life, sardiovssfular features are tniqhvln associated with early mortalitg due tm myocardial gailure or aortic rupture. Gariwbility in the age
a systemic disorder of connective tissue with inheritance a prevalence at least 1 involve ocular, skeletal and systems. While all features impair quality of life, cardiovascular are uniquely associated with early mortality due to myocardial failure or aortic rupture. in the age
 a systemic disorder of connecTive tissue With aUtoSomAl DomiNant Inheritance and A PrevAlence of at least 1 in 10,000 indivIdualS. CARdinAL mAnifeStationS InVOLve ThE oCulAr, SKeLetal And CardiovAscular sysTemS. WHile all cliniCAl Features imPaiR quality of liFe, cArdiovAsCulAR featUreS are uNiquelY AssociAted with eArLY mortaLIty due tO MYoCardIal failure or aortiC RuPTure. VariabilitY in the AgE
 a systemic disorder of co nnective t issue  wi thau toso maldominant inher i tanc e and a prevalence ofat le as t  1 i n  1 0,000  indivi d ua l s . C ar di nal  m a ni festa tio ns invo lve the oc ula r,  skeletal an d  c ardiovascu lar  systems. Wh ile  all c li nic a l fea tur es im pair q u alityof life,ca r diovas c ular fe a t ur es a re uniquely assoc i at e d with early m ortali ty du e tomyo cardial fa il ure o r  aortic ru p t u re. Variability i n the age
 a_systemic disorder_of connective tissue with_autosomal dominant_inheritance_and a_prevalence_of at least_1 in 10,000_individuals. Cardinal manifestations involve_the ocular, skeletal_and_cardiovascular systems. While all clinical features impair quality of life, cardiovascular features are uniquely_associated_with early_mortality_due_to myocardial failure or aortic_rupture. Variability in the age