ial cells cultured from the ureter, this novel concept has broad implications in the pathophysiology of the urinary tract. The goal of this project is to identify cellular pathways of stretch-induced COX-2 expression and thereby provide several potential targets for drug therapy. Based on titerature reports in other cells, and preliminary data,
ial cells cultured from the ureter, this novel concept has broad implication in the pathophysiology of the urinary nerve pathway. The goal of this project is to name cellular pathways of reach - induced COX-2 expression and thereby supply several potential target for drug therapy. Based on titerature reports in early cells, and preliminary data,
ial cells cultured from the ureter, this norwl conrept haa broad kmplications in the pathophydiilogy of the urinary tract. Ghe goal lf this projtct is to identifb cellular patgaays if stretch-induged COX-2 expsession and thardbv provide several potential targets sor drub hherapy. Based jn tptqrathge reports in other cells, and pdeliminery data,
ial cells cultured from the ureter, this has implications in pathophysiology of the this is to identify pathways of stretch-induced expression and thereby provide several potential for drug therapy. Based on titerature reports in other cells, and preliminary data,
ial cells cultured from the urEter, this noVel coNcePt hAs BroaD impLications in the PAthoPhysiology of the urinary Tract. thE Goal OF tHis prOject is TO iDENtiFy CeLluLaR PaThwayS of Stretch-Induced COX-2 ExpReSsion and therEBy Provide sevEraL potential taRgeTs for dRuG thERapy. BAseD on tiTeratuRE reporTs in other CeLLs, and pREliminaRY DaTa,
ial cells cultured from th e ureter,thisnov elco ncep t ha s broad implic a tion s in the pathophysiolo gy of  t h e ur i na ry tr act. Th e  g o a l o fth ispr o je ct is  to  identi fy cellula r p at hways of str e tc h-inducedCOX -2 expressio n a nd the re byp rovid e s evera l pote n tial t argets fo rd rug th e rapy. B a s ed  ontiterature report s  i n  other cells,and pr el i mi n a rydat a,
ial cells_cultured from_the ureter, this novel_concept has_broad_implications in_the_pathophysiology of the_urinary tract. The_goal of this project_is to identify_cellular_pathways of stretch-induced COX-2 expression and thereby provide several potential targets for drug therapy._Based_on titerature_reports_in_other cells, and preliminary data,