 diseases of mucosal surfaces, particularly in the intestine, is migration of large numbers of neutrophils (PMN) across the epithelium and accumulation within a lumen. In such conditions, disease symptoms are complex but directly related to leukocyte effects on the epithelial barrier and epithelial cell function. While much has been learned about mechanisms of leukocyte emigration
diseases of mucosal surfaces, particularly in the intestine, is migration of large number of neutrophil (PMN) across the epithelium and accumulation within a lumen. In such conditions, disease symptom are complex but immediately related to leukocyte effects on the epithelial barrier and epithelial cell affair. While much has been learned about mechanisms of leukocyte emigration
 dideases of mucosal surfacts, particularly iu the iitestins, is migfation of large numbers of nxutriphilw (PMN) across the epithdlium and accumulqtioi within a lumen. In such condiflons, biwease symptoms are complax but directlf fepated to leukocyte effects on the e[ithelisl barrier and ekithekyal dvlo function. While much has beeh learntd about mechanismx of leukocyte emigration
diseases of mucosal surfaces, particularly in the migration large numbers neutrophils (PMN) across a In such conditions, symptoms are complex directly related to leukocyte effects on epithelial barrier and epithelial cell function. While much has been learned about mechanisms leukocyte emigration
 diseases of mucosal surfaces, ParticularLy in tHe iNteStIne, iS migRation of large nUMberS of neutrophils (PMN) acrosS the ePiTHeliUM aNd accUmulatiON wITHin A lUmEn. IN sUCh CondiTioNs, diseaSe symptoms Are CoMplex but direCTlY related to LeuKocyte effectS on The epiThEliAL barrIer And epItheliAL cell fUnction. WhIlE Much haS Been leaRNEd AbouT mechanisms of leukOCyTE emigration
 diseases of mucosal surfa ces, parti cular lyinth e in test ine, is migrat i on o f large numbers of neu troph il s  (PM N )acros s the e p it h e liu man d a cc u mu latio n w ithin a  lumen. In  su ch  conditions, di sease symp tom s are comple x b ut dir ec tly relat edto le ukocyt e  effec ts on the  e p itheli a l barri e r  a nd e pithelial cell fu n ct i on. While much  has b ee n  l e a rne d a bout mecha ni sms o f  leukoc y te e m igr a tion
 diseases_of mucosal_surfaces, particularly in the_intestine, is_migration_of large_numbers_of neutrophils (PMN)_across the epithelium_and accumulation within a_lumen. In such_conditions,_disease symptoms are complex but directly related to leukocyte effects on the epithelial barrier_and_epithelial cell_function._While_much has been learned about_mechanisms of leukocyte emigration