 in vitro and in vivo, leading to increased production of a secreted receptor (sIL7R) that is unable to activate the IL-7 signaling pathway. Importantly, sIL7R has been linked to the disease in both human patients and animal models. These results directly implicate splicing of IL7R to the
in vitro and in vivo, leading to increased production of a secreted sense organ (sIL7R) that is ineffective to trip the IL-7 signaling pathway. Importantly, sIL7R has been linked to the disease in both human affected role and animal models. These results immediately implicate splicing of IL7R to the
 in vitro and in vivo, leadikg to increased kriductimn of z secretdd receptor (sIL7R) that is unaule ro acupvate the IL-7 signaline pathway. Importabtly, wIL7R has bxsn linkcb to fme divxase in both hukan patiends and animal koaeps. These results directly implicate splicimg of IL7R to the
in vitro and in vivo, leading to of secreted receptor that is unable pathway. sIL7R has been to the disease both human patients and animal models. results directly implicate splicing of IL7R to the
 in vitro and in vivo, leading to Increased pRoducTioN of A sEcreTed rEceptor (sIL7R) thaT Is unAble to activate the IL-7 sigNalinG pAThwaY. imPortaNtly, sIL7r HaS BEen LiNkEd tO tHE dIseasE in Both humAn patients And AnImal models. ThESe Results dirEctLy implicate sPliCing of iL7r to THe
 in vitro and in vivo, lea ding to in creas edpro du ctio n of  a secreted re c epto r (sIL7R) that is unab le to  a c tiva t ethe I L-7 sig n al i n g p at hw ay.  I m po rtant ly,  sIL7Rhas been l ink ed  to the dise a se  in both h uma n patients a ndanimal  m ode l s. Th ese  resu lts di r ectlyimplicate  s p licing of IL7R t othe
 in_vitro and_in vivo, leading to_increased production_of_a secreted_receptor_(sIL7R) that is_unable to activate_the IL-7 signaling pathway._Importantly, sIL7R has_been_linked to the disease in both human patients and animal models. These results directly_implicate_splicing of_IL7R_to_the