 localization in the Pur-alpha knockout mouse model, suggesting that Pur-alpha is required for their proper function. Based on these preliminary observations, we hypothesize that Pur-alpha has a central role in the well-balanced activities of RhoA and Rac, and that its genetic ablation or its functional alteration by associating with Tat
localization in the Pur - alpha knockout mouse model, suggesting that Pur - alpha is required for their proper affair. free-base on these preliminary observations, we hypothesize that Pur - alpha has a cardinal role in the well - balanced activities of RhoA and Rac, and that its familial ablation or its functional alteration by associate with Tat
 lofalization in the Pur-alpma knockout mousg nodel, vuggesfing thag Pur-alpha is required for tieir proptg function. Based on tfese prelpminary ovsertations, we hypotissize tmct Pud-wlphc ias a central rple in the well-balanced dcgirities of RhoA and Rac, and that its denetic ahlation or its funbtyonam alteration by associating with Tzt
localization in the Pur-alpha knockout mouse model, Pur-alpha required for proper function. Based hypothesize Pur-alpha has a role in the activities of RhoA and Rac, and its genetic ablation or its functional alteration by associating with Tat
 localization in the Pur-alpha Knockout moUse moDel, SugGeStinG thaT Pur-alpha is reqUIred For their proper function. based On THese PReLiminAry obseRVaTIOns, We HyPotHeSIzE that pur-Alpha haS a central rOle In The well-balanCEd Activities Of RHoA and Rac, and ThaT its geNeTic ABlatiOn oR its fUnctioNAl alteRation by aSsOCiatinG With Tat
 localization in the Pur-a lpha knock out m ous e m od el,sugg esting that Pu r -alp ha is required for the ir pr op e r fu n ct ion.Based o n  t h e sepr el imi na r yobser vat ions, w e hypothes ize  t hat Pur-alph a  h as a centr alrole in thewel l-bala nc eda ctivi tie s ofRhoA a n d Rac,  and that  i t s gene t ic abla t i on  orits functional al t er a tion by associ atingwi t hT a t
 localization_in the_Pur-alpha knockout mouse model,_suggesting that_Pur-alpha_is required_for_their proper function._Based on these_preliminary observations, we hypothesize_that Pur-alpha has_a_central role in the well-balanced activities of RhoA and Rac, and that its genetic_ablation_or its_functional_alteration_by associating with Tat