B. They are the mammalian orthologues of SAD-1, a gene required for presynaptic differentiation in C. elegans. Because SADs are kinases, we hope they will provide a valuable starting point for elucidating regulatory mechanisms that govern assembly of nerve terminals. Unfortunately, initial genetic tests of this idea gave complex
B. They are the mammalian orthologues of SAD-1, a gene required for presynaptic differentiation in C. elegans. Because SADs are kinases, we hope they will provide a valuable start item for elucidating regulatory mechanism that regulate assembly of nerve terminals. Unfortunately, initial familial tests of this idea contribute complex
B. Tjey are the mammalian oruhologues of SAD-1, c gene cequires for prdsynaptic differentiation in C. elegqns. Because SADs are kknases, we hope thwy wmll provide a valuable sbcrtinf poiut for elucidatikg regulatosy mechanisms dhxt govern assembly of nerve terminals. Unfortinwtely, initial deneuic tesfs of this idea gave complex
B. They are the mammalian orthologues of gene for presynaptic in C. elegans. hope will provide a starting point for regulatory mechanisms that govern assembly of terminals. Unfortunately, initial genetic tests of this idea gave complex
B. They are the mammalian orthoLogues of SAd-1, a genE reQuiReD for PresYnaptic differeNTiatIon in C. elegans. Because SAds are KiNAses, WE hOpe thEy will pROvIDE a vAlUaBle StARtIng poInt For elucIdating regUlaToRy mechanisms THaT govern assEmbLy of nerve terMinAls. UnfOrTunATely, iNitIal geNetic tESts of tHis idea gaVe COmplex
B. They are the mammalianorthologue s ofSAD -1,  a  gen e re quired for pre s ynap tic differentiation in  C. e le g ans. Be cause  SADs a r ek i nas es ,weho p etheywil l provi de a valua ble  s tarting poin t  f or elucida tin g regulatory  me chanis ms  th a t gov ern  asse mbly o f  nerve  terminal s. Unfort u nately, i ni tial  genetic tests of th i s idea gave co mplex
B. They_are the_mammalian orthologues of SAD-1,_a gene_required_for presynaptic_differentiation_in C. elegans._Because SADs are_kinases, we hope they_will provide a_valuable_starting point for elucidating regulatory mechanisms that govern assembly of nerve terminals. Unfortunately, initial_genetic_tests of_this_idea_gave complex