 studies of cancer, and development of a set of interactive computer programs which can be used to analyze the trends of cancer rates over time. The central purpose of the proposed research is to define the roles which drug metabolism and pharmacokinetic factors play in determining the clinical response to certain commonly abused drugs, including the predisposition for compulsive
studies of cancer, and development of a set of interactive calculator broadcast which can be used to analyze the trends of cancer pace over fourth dimension. The central purpose of the nominate inquiry is to define the roles which drug metabolism and pharmacokinetic factors play in specify the clinical response to certain normally abused drugs, including the predisposition for compulsive
 stkdies of cancer, and deveuopment of a sej if intxractivs computdr programs which can be usev to analtze the trends of cancdr rates lver timw. Tht central purpose of the ixopossf revxarch is to deflne the rolas which drug kegayolism and pharmacokinetic factors pjay in cehermining the slinpcwl rssponse to certain commonly abused drugs, pncluding the precisposition for compulsive
studies of cancer, and development of a interactive programs which be used to rates time. The central of the proposed is to define the roles which metabolism and pharmacokinetic factors play in determining the clinical response to certain commonly drugs, including the predisposition for compulsive
 studies of cancer, and developMent of a set Of intEraCtiVe CompUter Programs which cAN be uSed to analyze the trends oF cancEr RAtes OVeR time. the centRAl PURpoSe Of The PrOPoSed reSeaRch is to Define the rOleS wHich drug metaBOlIsm and pharMacOkinetic factOrs Play in DeTerMIning The CliniCal resPOnse to Certain coMmONly abuSEd drugs, INClUdinG the predispositioN FoR Compulsive
 studies of cancer, and de velopmentof aset  of  i nter acti ve computer pr o gram s which can be used to  anal yz e  the tr endsof canc e rr a tes  o ve r t im e .The c ent ral pur pose of th e p ro posed resear c his to defi nethe roles wh ich  drugme tab o lismand  phar macoki n etic f actors pl ay in det e rmining t he  cli nical response to ce r tain commonlyabused  d r ug s ,  in clu ding the p re dispo s ition f o rc o m pul s ive
 studies_of cancer,_and development of a_set of_interactive_computer programs_which_can be used_to analyze the_trends of cancer rates_over time. The_central_purpose of the proposed research is to define the roles which drug metabolism and_pharmacokinetic_factors play_in_determining_the clinical response to certain_commonly abused drugs, including the_predisposition for_compulsive