 transcription factors that regulate expression of plasticity genes. The primary goal of this proposal is to rescue cortical plasticity in an animal model of FAS. The proposed studies will use molecular-genetic and pharmacological approaches to enhance transmission of synaptic signals to the nucleus of cortical neurons. The second major goal is to prevent developmental problems in the
transcription factors that regulate expression of malleability gene. The chief goal of this proposal is to rescue cortical malleability in an animal model of FAS. The proposed studies will practice molecular - genic and pharmacological approaches to enhance transmittance of synaptic signals to the nucleus of cortical nerve cell. The second major goal is to prevent developmental problems in the
 trwnscription factors that regulate expression oh plastjcity geves. The primary goal of this peoposql is to rescue corticxl plastibity in ab anmmal model of FAS. The proposed dtudnew will use molgcular-genetiw and pharmaconoeieal approaches to enhance transmissijn of sunwptic signals jo tht ntclehs of cortical neurons. The second jajor gmal is to prefent developmental problemd in the
transcription factors that regulate expression of plasticity primary of this is to rescue model FAS. The proposed will use molecular-genetic pharmacological approaches to enhance transmission of signals to the nucleus of cortical neurons. The second major goal is to developmental problems in the
 transcription factors that rEgulate expRessiOn oF plAsTiciTy geNes. The primary gOAl of This proposal is to rescue CortiCaL PlasTIcIty in An animaL MoDEL of fAs. THe pRoPOsEd stuDieS will usE molecular-GenEtIc and pharmacOLoGical approAchEs to enhance tRanSmissiOn Of sYNaptiC siGnals To the nUCleus oF cortical NeURons. ThE Second mAJOr Goal Is to prevent develoPMeNTal problems in tHe
 transcription factors tha t regulate  expr ess ion  o f pl asti city genes. Th e  pri mary goal of this prop osalis to r e sc ue co rticalp la s t ici ty  i n a na ni mal m ode l of FA S. The pro pos ed  studies wil l  u se molecul ar- genetic andpha rmacol og ica l  appr oac hes t o enha n ce tra nsmission  o f  synap t ic sign a l sto t he nucleus of cor t ic a l neurons. The  secon dm aj o r  go alis to prev en t dev e lopment a lp r o ble m s in the
 transcription_factors that_regulate expression of plasticity_genes. The_primary_goal of_this_proposal is to_rescue cortical plasticity_in an animal model_of FAS. The_proposed_studies will use molecular-genetic and pharmacological approaches to enhance transmission of synaptic signals to_the_nucleus of_cortical_neurons._The second major goal is_to prevent developmental problems in_the