 changes in alternative splicing occur during this process. A change in this splicing network is a thus a dynamic feature of the EMT and changes in splicing of ESRP-regulated targets can be used as a biomarker for the EMT. In this application we will develop more robust next generation splicing reporter assays using ESRP- regulated exons that
changes in alternative splicing occur during this procedure. A variety in this splicing network is a therefore a dynamic feature of speech of the EMT and changes in splicing of ESRP - baffle target can be used as a biomarker for the EMT. In this lotion we will originate more robust future generation splicing reporter assay using ESRP- regulated exons that
 chwnges in alternative spllcing occur duriut this proceas. A chavge in this splicing network iw a tyus a dynamic feature uf the EMN and chabges un splicinj of ESRI-xegulzbed tcrjets can be usec as a biokarker for the EOT. In this application we will develo[ more tohust next genetatiom spljbikg reporter assays using ESRP- refulated exons that
changes in alternative splicing occur during this change this splicing is a thus EMT changes in splicing ESRP-regulated targets can used as a biomarker for the In this application we will develop more robust next generation splicing reporter assays ESRP- regulated exons that
 changes in alternative splicIng occur duRing tHis ProCeSs. A cHangE in this splicinG NetwOrk is a thus a dynamic featUre of ThE eMT aND cHangeS in spliCInG OF ESrP-ReGulAtED tArgetS caN be used As a biomarkEr fOr The EMT. In this APpLication we WilL develop more RobUst nexT gEneRAtion SplIcing ReportER assayS using ESRp- rEGulateD Exons thAT
 changes in alternative sp licing occ ur du rin g t hi s pr oces s. A change in this  splicing network is a  thus  a dyna m ic  feat ure oft he E MTan dcha ng e sin sp lic ing ofESRP-regul ate dtargets canb eused as abio marker for t heEMT. I nthi s  appl ica tionwe wil l  devel op more r ob u st nex t  genera t i on  spl icing reporter as s ay s  using ESRP- r egulat ed ex o n s t hat 
 changes_in alternative_splicing occur during this_process. A_change_in this_splicing_network is a_thus a dynamic_feature of the EMT_and changes in_splicing_of ESRP-regulated targets can be used as a biomarker for the EMT. In this_application_we will_develop_more_robust next generation splicing reporter_assays using ESRP- regulated exons_that