 the flippases facilitate 'downhill' transport of lipids; this distinguishes ER flippases from other translocators, typically found in the eukaryotic plasma membrane, that couple ATP hydrolysis to concentrative 'uphill' transport of lipids. We estimate that there are as many as six different ER lipid flippases but
the flippases facilitate' downhill' transport of lipids; this distinguishes ER flippases from early translocators, typically discover in the eukaryotic plasma membrane, that couple ATP hydrolysis to concentrative' uphill' transport of lipid. We estimate that there be as many as six different ER lipid flippases but
 thf flippases facilitate 'duwnhill' transpott of li'ids; thjs distivguishes ER flippases from ovher tranwlocators, typically fojnd in thv eukaryoric klasma membrane, tizt couple ATP mydronbsis to concenttative 'uphiln' transport of lkpnds. We estimate that there are as magy as sox different ER jipic fliliawes but
the flippases facilitate 'downhill' transport of lipids; ER from other typically found in couple hydrolysis to concentrative transport of lipids. estimate that there are as many six different ER lipid flippases but
 the flippases facilitate 'dowNhill' transPort oF liPidS; tHis dIstiNguishes ER flipPAses From other translocators, TypicAlLY fouND iN the eUkaryotIC pLASma MeMbRanE, tHAt CouplE ATp hydrolYsis to concEntRaTive 'uphill' trANsPort of lipiDs. WE estimate thaT thEre are As ManY As six DifFerenT ER lipID flippAses but
 the flippases facilitate'downhill'  tran spo rtof  lip ids;  this distingu i shes  ER flippases from oth er tr an s loca t or s, ty pically fo u n d i nth e e uk a ry oticpla sma mem brane, tha t c ou ple ATP hydr o ly sis to con cen trative 'uph ill ' tran sp ort of li pid s. We  estim a te tha t there a re as man y  as six d if fere nt ER lipid flipp a se s  but
 the_flippases facilitate_'downhill' transport of lipids;_this distinguishes_ER_flippases from_other_translocators, typically found_in the eukaryotic_plasma membrane, that couple_ATP hydrolysis to_concentrative_'uphill' transport of lipids. We estimate that there are as many as six different_ER_lipid flippases_but