-induced spinal glia activation in the modulation of visceral sensitivity and determine the molecular pathways engaged in the initiation and maintenance of visceral hyperalgesia. Our first specific aim is to assess the temporal profile of spinal glia activation during and after chronic stress and to test the ability of inhibitors specific of glia to reduce stress
-induced spinal glia activation in the modulation of visceral sensitivity and settle the molecular nerve pathway engaged in the initiation and maintenance of intuitive hyperalgesia. Our first specific aim is to assess the worldly visibility of spinal glia activation during and after chronic stress and to test the ability of inhibitors specific of neuroglia to reduce stress
-indkced spinal glia activatlon in the modulcrion oh viscedal sensktivity and determine the mopexular pathways engaged in tfe initianion and nainuenance of viscerem hyperalgesiz. Our hirst specific sim is to dssess the tem[ofap profile of spinal glia activation during ajd after chronyc surefs ahd to test the ability of inhibitods specpfic of glia to rrduce stress
-induced spinal glia activation in the modulation sensitivity determine the pathways engaged in visceral Our first specific is to assess temporal profile of spinal glia activation and after chronic stress and to test the ability of inhibitors specific of to reduce stress
-induced spinal glia activatiOn in the modUlatiOn oF viScEral SensItivity and deteRMine The molecular pathways enGaged In THe inITiAtion And mainTEnANCe oF vIsCerAl HYpEralgEsiA. Our firSt specific Aim Is To assess the tEMpOral profilE of Spinal glia acTivAtion dUrIng ANd aftEr cHroniC stresS And to tEst the abiLiTY of inhIBitors sPECiFic oF glia to reduce streSS
-induced spinal glia activ ation in t he mo dul ati on  ofvisc eral sensitivi t y an d determine the molecu lar p at h ways en gaged  in the in i t iat io nand  m a in tenan ceof visc eral hyper alg es ia. Our firs t  s pecific ai m i s to assessthe  tempo ra l p r ofile  of  spin al gli a  activ ation dur in g  and a f ter chr o n ic  str ess and to test t h ea bility of inhi bitors  s p ec i f icofglia to re du ce st r ess
-induced spinal_glia activation_in the modulation of_visceral sensitivity_and_determine the_molecular_pathways engaged in_the initiation and_maintenance of visceral hyperalgesia._Our first specific_aim_is to assess the temporal profile of spinal glia activation during and after chronic_stress_and to_test_the_ability of inhibitors specific of_glia to reduce stress