. Half are also randomly allocated to receive 3 zoledronic acid infusions, one every 6 months. Bone mineral density and serologic markers of bone metabolism are the primary study endpoints. GOG-199 participants who cross-over from screening to surgery remain eligible for this study. The entry criteria have been relaxed to
. Half are also randomly allocated to receive 3 zoledronic acid infusion, one every 6 calendar month. Bone mineral density and serologic markers of bone metabolism are the elementary study endpoints. GOG-199 player who crossbreed - over from screen to surgery remain eligible for this study. The entrance criteria have been relaxed to
. Hapf are also randomly allucated to receirw 3 zolxdronic acid inwusions, one every 6 months. Boie munerao density and serologiz markers of bone metebolism are the 'dimary study skdpoiutw. GOG-199 participsnts who csoss-over from vcfezning to surgery remain eligible for this syufy. The entry ctiterpa havs been relaxed to
. Half are also randomly allocated to zoledronic infusions, one 6 months. Bone of metabolism are the study endpoints. GOG-199 who cross-over from screening to surgery eligible for this study. The entry criteria have been relaxed to
. Half are also randomly allocaTed to receiVe 3 zolEdrOniC aCid iNfusIons, one every 6 moNThs. BOne mineral density and seRologIc MArkeRS oF bone MetabolISm ARE thE pRiMarY sTUdY endpOinTs. GOG-199 paRticipants Who CrOss-over from sCReEning to surGerY remain eligiBle For thiS sTudY. the enTry CriteRia havE Been reLaxed to
. Half are also randomly a llocated t o rec eiv e 3  z oled roni c acid infusio n s, o ne every 6 months. Bon e min er a l de n si ty an d serol o gi c mar ke rs  of  b o ne  meta bol ism are  the prima ryst udy endpoint s .GOG-199 pa rti cipants whocro ss-ove rfro m  scre eni ng to  surge r y rema in eligib le for th i s study . Th e en try criteria have be e n relaxed to
. Half_are also_randomly allocated to receive_3 zoledronic_acid_infusions, one_every_6 months. Bone_mineral density and_serologic markers of bone_metabolism are the_primary_study endpoints. GOG-199 participants who cross-over from screening to surgery remain eligible for this_study._The entry_criteria_have_been relaxed to