 signaling events following PS-PSR recognition. In addition, we will test whether the disruption of PS-PSR recognition in the embryonic brain will alter the apoptosis of neural progenitor cells. Aim 2: We will examine the interaction between the JNK and canonical Wnt/beta-catenin signaling in the decision of self-renewal
signaling events following PS - PSR recognition. In accession, we will screen whether the disruption of PS - PSR recognition in the embryonic brain will change the apoptosis of neural progenitor cells. bearing 2: We will probe the interaction between the JNK and canonical Wnt / beta - catenin signaling in the decision of self - renewal
 sihnaling events following PS-PSR recognitnin. In edditioh, we wilu test whether the disruptioi of PS-PSE recognition in the eobryonic hrain wiol aorer the apoptosis of neudwl pxojenitor cells. Alm 2: We will examine the ittdrcction between the JNK and canonical Wnt/bets-cwtenin signaligg im the decision of self-renewal
signaling events following PS-PSR recognition. In addition, test the disruption PS-PSR recognition in the of neural progenitor Aim 2: We examine the interaction between the JNK canonical Wnt/beta-catenin signaling in the decision of self-renewal
 signaling events following Ps-PSR recognItion. in aDdiTiOn, we Will Test whether the DIsruPtion of PS-PSR recognitioN in thE eMBryoNIc Brain Will altER tHE ApoPtOsIs oF nEUrAl proGenItor celLs. Aim 2: We wilL exAmIne the interaCTiOn between tHe JnK and canonicAl WNt/beta-CaTenIN signAliNg in tHe deciSIon of sElf-renewaL
 signaling events followin g PS-PSR r ecogn iti on.  I n ad diti on, we will te s t wh ether the disruption o f PS- PS R  rec o gn ition  in the em b r yon ic  b rai nw il l alt erthe apo ptosis ofneu ra l progenitor ce lls. Aim 2 : W e will exami nethe in te rac t ion b etw een t he JNK and ca nonical W nt / beta-c a tenin s i g na ling  in the decisiono fs elf-renewal
 signaling_events following_PS-PSR recognition. In addition,_we will_test_whether the_disruption_of PS-PSR recognition_in the embryonic_brain will alter the_apoptosis of neural_progenitor_cells. Aim 2: We will examine the interaction between the JNK and canonical Wnt/beta-catenin_signaling_in the_decision_of_self-renewal