 potential mechanisms that explain contribution of CD8 T cells to elimination of Plasmodium liver stages in mice. We will provide such insights via three complementary speci?c aims. In speci?c Aim 1, we will discriminate between alternative mechanisms of formation of CD8 T cell clusters around sporozoite-infected hepatocytes
potential mechanisms that explain contribution of CD8 T cells to elimination of Plasmodium liver stage in mouse. We will provide such insights via three complementary speci?c aim. In speci?c Aim 1, we will discriminate between alternative mechanisms of geological formation of CD8 T cellular telephone clusters around sporozoite - infected hepatocytes
 pohential mechanisms that txplain contributnin of RD8 T cemls to euimination of Plasmodium livxr srages in mice. We will proviae such ijsights cia uhree complementacg speci?g aima. In v'eci?c Aim 1, we wlll discrimhnate between dlgexnative mechanisms of formation of CQ8 T celk flusters arounq sppwozojne-lnfected hepatocytes
potential mechanisms that explain contribution of CD8 to of Plasmodium stages in mice. via complementary speci?c aims. speci?c Aim 1, will discriminate between alternative mechanisms of of CD8 T cell clusters around sporozoite-infected hepatocytes
 potential mechanisms that exPlain contrIbutiOn oF CD8 t cElls To elImination of PlaSModiUm liver stages in mice. We wIll prOvIDe suCH iNsighTs via thREe COMplEmEnTarY sPEcI?c aimS. In Speci?c AIm 1, we will diScrImInate between ALtErnative meChaNisms of formaTioN of CD8 T CeLl cLUsterS arOund sPorozoITe-infeCted hepatOcYTes
 potential mechanisms that  explain c ontri but ion  o f CD 8 Tcells to elimi n atio n of Plasmodium liverstage si n mi c e.  We w ill pro v id e suc hin sig ht s  v ia th ree  comple mentary sp eci ?c  aims. In sp e ci ?c Aim 1,wewill discrim ina te bet we ena ltern ati ve me chanis m s of f ormationof CD8 Tc ell clu s t er s ar ound sporozoite-i n fe c ted hepatocyte s
 potential_mechanisms that_explain contribution of CD8_T cells_to_elimination of_Plasmodium_liver stages in_mice. We will_provide such insights via_three complementary speci?c_aims._In speci?c Aim 1, we will discriminate between alternative mechanisms of formation of CD8_T_cell clusters_around_sporozoite-infected_hepatocytes