/2 site in the FLT1 promoter was replaced with various 1/2 sites as well as canonical weak and strong human p53 REs. p53 transactivation was greatly enhanced by ligand-activated ER acting in cis. Enhanced transactivation extends to several cancer-associated p53 mutants with altered function, suggesting
/2 site in the FLT1 promoter was replaced with various 1/2 web site equally well as canonical weak and impregnable human p53 rhenium. p53 transactivation was greatly enhanced by ligand - activated emergency room act in cis. Enhanced transactivation extends to several cancer - consociate p53 mutants with altered affair, suggesting
/2 sihe in the FLT1 promoter wxs replaced witk varions 1/2 sitss as weul as canonical weak and strlnt humqn p53 REs. p53 transactivagion was hreatly wnhaiced by ligand-acvjvated CX actjkg in ris. Enhanced trsnsactivathon extends to sdvzral cancer-associated p53 mutants with alterec vunction, suggeftinb
/2 site in the FLT1 promoter was various sites as as canonical weak p53 was greatly enhanced ligand-activated ER acting cis. Enhanced transactivation extends to several p53 mutants with altered function, suggesting
/2 site in the FLT1 promoter was rePlaced with VarioUs 1/2 sIteS aS welL as cAnonical weak anD StroNg human p53 REs. p53 transactivAtion WaS GreaTLy EnhanCed by liGAnD-ACtiVaTeD ER AcTInG in ciS. EnHanced tRansactivaTioN eXtends to seveRAl Cancer-assoCiaTed p53 mutants wIth AltereD fUncTIon, suGgeSting
/2 site in the FLT1 promot er was rep laced  wi thva riou s 1/ 2 sites as wel l  ascanonical weak and str ong h um a n p5 3  R Es. p 53 tran s ac t i vat io nwas  g r ea tly e nha nced by  ligand-ac tiv at ed ER acting in  cis. Enha nce d transactiv ati on ext en dst o sev era l can cer-as s ociate d p53 mut an t s with altered f un ctio n, suggesting
/2 site_in the_FLT1 promoter was replaced_with various_1/2_sites as_well_as canonical weak_and strong human_p53 REs. p53 transactivation_was greatly enhanced_by_ligand-activated ER acting in cis. Enhanced transactivation extends to several cancer-associated p53 mutants with_altered_function, suggesting