 inflammation at baseline and with changes in inflammation over time in older adults; and (3) determine whether, and to what degree, inflammation reduces the effect of MetS on physical function. Statistical methods to be used include logistic regression and mixed effects modeling, as well as mediation analysis. This project will provide a practical opportunity for
inflammation at baseline and with changes in inflammation over meter in previous adults; and (3) determine whether, and to what degree, ignition reduces the effect of MetS on forcible function. Statistical methods to be used admit logistic arrested development and mixed effects model, as well as mediation analysis. This project will leave a practical opportunity for
 invlammation at baseline akd with changes nb inflemmatioh over tkme in older adults; and (3) detxrmibe whtnher, and to what degrde, inflamlation rwducts the effect of MetS on ikysiczp fuucvion. Statisticak methods do be used incnuae logistic regression and mixed effests modrllng, as well as medpaeion analysis. This project will provids a prabtical opportunitu for
inflammation at baseline and with changes in time older adults; (3) determine whether, reduces effect of MetS physical function. Statistical to be used include logistic regression mixed effects modeling, as well as mediation analysis. This project will provide a opportunity for
 inflammation at baseline and With changeS in inFlaMmaTiOn ovEr tiMe in older adultS; And (3) dEtermine whether, and to whAt degReE, InflAMmAtion Reduces THe EFFecT oF MEtS On PHySical FunCtion. StAtistical mEthOdS to be used incLUdE logistic rEgrEssion and mixEd eFfects MoDelINg, as wEll As medIation ANalysiS. This projEcT Will prOVide a prACTiCal oPportunity for
 inflammation at baselineand with c hange s i n i nf lamm atio n over time in olde r adults; and (3) dete rmine  w h ethe r ,and t o whatd eg r e e,in fl amm at i on  redu ces  the ef fect of Me tSon  physical fu n ct ion. Stati sti cal methodstobe use dinc l ude l ogi sticregres s ion an d mixed e ff e cts mo d eling,a s  w ellas mediation anal y si s . This project  willpr o vi d e  apra ctical opp or tunit y  for
 inflammation_at baseline_and with changes in_inflammation over_time_in older_adults;_and (3) determine_whether, and to_what degree, inflammation reduces_the effect of_MetS_on physical function. Statistical methods to be used include logistic regression and mixed effects_modeling,_as well_as_mediation_analysis. This project will provide_a practical opportunity for