 superimposed acute injury. This Project is critically linked to Project 1, as studies in chronic AB-enrichment in the CMSstrongly support deleterious and maladaptive roles for RAGE in neuronal stress. As antagonism of RAGE nears clinical trials in Alzheimer's Disease and diabetes, it is imperative to dissect
superimposed acute injury. This Project is critically linked to Project 1, as report in chronic AB - enrichment in the CMSstrongly documentation deleterious and maladaptive roles for RAGE in neuronal tension. As antagonism of RAGE nears clinical trials in Alzheimer's Disease and diabetes, it is imperative to analyze
 suoerimposed acute injury. Uhis Project is ctiricallb linkes to Progect 1, as studies in chronic EB-eneichmtut in the CMSstronglh support deleteruous qnd malada'five roles fod RAGZ mn neuronal strgss. As antagmnism of RAGE texrd clinical trials in Alzheimer's Disqase anc fiabetes, it is imptraeive no dissect
superimposed acute injury. This Project is critically Project as studies chronic AB-enrichment in maladaptive for RAGE in stress. As antagonism RAGE nears clinical trials in Alzheimer's and diabetes, it is imperative to dissect
 superimposed acute injury. ThIs Project iS critIcaLly LiNked To PrOject 1, as studies IN chrOnic AB-enrichment in the CmSstrOnGLy suPPoRt delEteriouS AnD MAlaDaPtIve RoLEs For RAgE iN neuronAl stress. As AntAgOnism of RAGE nEArS clinical tRiaLs in AlzheimeR's DIsease AnD diABetes, It iS impeRative TO disseCt
 superimposed acute injury . This Pro jectiscri ti call y li nked to Projec t  1,as studies in chronicAB-en ri c hmen t  i n the  CMSstr o ng l y  su pp or t d el e te rious  an d malad aptive rol esfo r RAGE in ne u ro nal stress . A s antagonism  of  RAGEne ars clini cal  tria ls inA lzheim er's Dise as e  and d i abetes, i tis i mperative to diss e ct 
 superimposed_acute injury._This Project is critically_linked to_Project_1, as_studies_in chronic AB-enrichment_in the CMSstrongly_support deleterious and maladaptive_roles for RAGE_in_neuronal stress. As antagonism of RAGE nears clinical trials in Alzheimer's Disease and diabetes,_it_is imperative_to_dissect