 loci. We now propose to elucidate further the role of NHEJ proteins in CSR and SM, with a particular focus on how defects in these processes, and in V(D)J recombination, may lead to the generation of chromosomal translocations that contribute to the generation and maintenance of mature B cell lymphomas.
loci. We now propose to elucidate far the function of NHEJ proteins in CSR and SM, with a particular focus on how defect in these processes, and in V(D)J recombination, may lead to the genesis of chromosomal translocation that contribute to the coevals and maintenance of mature bel cell lymphomas.
 lofi. We now propose to elugidate further tkw role of NHSJ protekns in CSR and SM, with a parvicuoar ficus on how defects in these prlcesses, qnd mn V(D)J recombinavjon, may lead fl thz jeneration of cmromosomal dranslocations tfac contribute to the generation and mwintenamcf of mature B sell jympgomas.
loci. We now propose to elucidate further of proteins in and SM, with defects these processes, and V(D)J recombination, may to the generation of chromosomal translocations contribute to the generation and maintenance of mature B cell lymphomas.
 loci. We now propose to elucidaTe further tHe rolE of nHEj pRoteIns iN CSR and SM, with a PArtiCular focus on how defects In theSe PRoceSSeS, and iN V(D)J recOMbINAtiOn, MaY leAd TO tHe genEraTion of cHromosomal TraNsLocations thaT CoNtribute to The Generation anD maIntenaNcE of MAture b ceLl lymPhomas.
 loci. We now propose to e lucidate f urthe r t hero le o f NH EJ proteins in CSRand SM, with a particu lar f oc u s on ho w def ects in th e s e p ro ce sse s, an d inV(D )J reco mbination,  ma ylead to theg en eration of  ch romosomal tr ans locati on s t h at co ntr ibute  to th e  gener ation and  m a intena n ce of m a t ur e Bcell lymphomas.
 loci._We now_propose to elucidate further_the role_of_NHEJ proteins_in_CSR and SM,_with a particular_focus on how defects_in these processes,_and_in V(D)J recombination, may lead to the generation of chromosomal translocations that contribute to_the_generation and_maintenance_of_mature B cell lymphomas.