 isolated hepatic metastases. These tumors often cause debilitating symptoms due to excessive hormonal secretion. Besides surgery, there are limited curative and palliative treatments available to patients with metastatic NE tumors, emphasizing the need for development of other forms of therapy. In this proposal, we will present data illustrating that GSK3B inhibition may be a
isolated hepatic metastases. These tumors often induce enfeeble symptom due to excessive hormonal secretion. Besides surgery, there be circumscribed curative and palliative treatments available to patients with metastatic NE tumor, underscore the need for growth of other forms of therapy. In this marriage proposal, we will present data illustrating that GSK3B inhibition may be a
 isllated hepatic metastaser. These tumors often ceuse degilitativg symptoms due to excessive hirmonql secretion. Besides sjrgery, thvre are lumittd curative and pemliativc trezbmentv available to katients witv metastatic NA gulors, emphasizing the need for develjpment pf other forms os thtra[y. Ih this proposal, we will present dafa illuvtrating that GSK3B inhibition may be a
isolated hepatic metastases. These tumors often cause due excessive hormonal Besides surgery, there treatments to patients with NE tumors, emphasizing need for development of other forms therapy. In this proposal, we will present data illustrating that GSK3B inhibition may a
 isolated hepatic metastases. these tumorS ofteN caUse DeBiliTatiNg symptoms due tO ExceSsive hormonal secretion. besidEs SUrgeRY, tHere aRe limitED cURAtiVe AnD paLlIAtIve trEatMents avAilable to pAtiEnTs with metastATiC NE tumors, eMphAsizing the neEd fOr deveLoPmeNT of otHer Forms Of therAPy. In thIs proposaL, wE Will prESent datA ILlUstrAting that GSK3B inhiBItIOn may be a
 isolated hepatic metastas es. Thesetumor s o fte ncaus e de bilitating sym p toms  due to excessive horm onalse c reti o n.  Besi des sur g er y ,  th er eare  l i mi ted c ura tive an d palliati vetr eatments ava i la ble to pat ien ts with meta sta tic NE  t umo r s, em pha sizin g then eed fo r develop me n t of o t her for m s  o f th erapy. In this pr o po s al, we will pr esentda t ai l lus tra ting thatGS K3B i n hibitio n  m a y bea 
 isolated_hepatic metastases._These tumors often cause_debilitating symptoms_due_to excessive_hormonal_secretion. Besides surgery,_there are limited_curative and palliative treatments_available to patients_with_metastatic NE tumors, emphasizing the need for development of other forms of therapy. In_this_proposal, we_will_present_data illustrating that GSK3B inhibition_may be a