 to learn whether the proposed treatment induces tumor- specific T cell responses and generates a tumor immune signature consistent with immunological rejection. The proposed studies will create the basis for a potential paradigm shift with direct clinical implications: harnessing a novel combination to effectively immunize the patient to her own tumor, and thereby achieving a response of the
to learn whether the proposed treatment induces tumor- specific metric ton cellular telephone responses and generates a tumor immune touch coherent with immunological rejection. The proposed studies will produce the footing for a potential paradigm shift with direct clinical implications: rule a novel combination to effectively immunize the affected role to her own tumor, and thereby achieving a response of the
 to learn whether the propored treatment iueuces vumor- slecific G cell responses and generatxs a tumoe immune signature conristent wpth immunilogmcal rejection. Tis proposed sthfies xill create the basis for a potential pdrxdngm shift with direct clinical implisations: hwrnessing a nodel boibinzniin to effectively immunize ths patieit to her own timor, and thereby achieving a rfsponse of the
to learn whether the proposed treatment induces T responses and a tumor immune The studies will create basis for a paradigm shift with direct clinical implications: a novel combination to effectively immunize the patient to her own tumor, and achieving a response of the
 to learn whether the proposed Treatment iNduceS tuMor- SpEcifIc T cEll responses anD GeneRates a tumor immune signaTure cOnSIsteNT wIth imMunologICaL REjeCtIoN. ThE pROpOsed sTudIes will Create the bAsiS fOr a potential PArAdigm shift WitH direct cliniCal ImplicAtIonS: HarneSsiNg a noVel comBInatioN to effectIvELy immuNIze the pATIeNt to Her own tumor, and theREbY Achieving a respOnse of ThE
 to learn whether the prop osed treat mentind uce stumo r- s pecific T cell resp onses and generates atumor  i m mune si gnatu re cons i st e n t w it himm un o lo gical  re jection . The prop ose dstudies will cr eate the b asi s for a pote nti al par ad igm shift  wi th di rect c l inical  implicat io n s: har n essinga no velcombination to ef f ec t ively immunize  the p at i en t toher  own tumor ,and t h ereby a c hi e v i nga  response ofthe
 to_learn whether_the proposed treatment induces_tumor- specific_T_cell responses_and_generates a tumor_immune signature consistent_with immunological rejection. The_proposed studies will_create_the basis for a potential paradigm shift with direct clinical implications: harnessing a novel_combination_to effectively_immunize_the_patient to her own tumor,_and thereby achieving a response_of the