rosinase, whereas R298W is located within the Cys-rich motif 2. The mutations N364H, P384A, D394N, D437N and R403V disrupt the coordination of the copper ion center. A490D affects conformation of helix located in melanosomal membrane. TYRP
rosinase, whereas R298W is located within the Cys - rich motif 2. The mutations N364H, P384A, D394N, D437N and R403V interrupt the coordination of the bull ion center. A490D affects shape of coil located in melanosomal membrane. TYRP
roslnase, whereas R298W is locaued within the Cys-rich mmtif 2. Fhe mutagions N364H, P384A, D394N, D437N and R403V discupt the xoordination of the cooper ion benter. A490D afftcts conformation of heliw loczbed iu nelanosomal mekbrane. TYR[
rosinase, whereas R298W is located within the 2. mutations N364H, D394N, D437N and the ion center. A490D conformation of helix in melanosomal membrane. TYRP
rosinase, whereas R298W is locateD within the cys-riCh mOtiF 2. THe muTatiOns N364H, P384A, D394N, D437N and r403v disRupt the coordination of tHe copPeR Ion cENtEr. A490D aFfects cONfORMatIoN oF heLiX LoCated In mElanosoMal membranE. TYrP
rosinase, whereas R298W is  located w ithin  th e C ys -ric h mo tif 2. The mut a tion s N364H, P384A, D394N,  D437 Na nd R 4 03 V dis rupt th e  c o o rdi na ti onof th e cop per  ion ce nter. A490 D a ff ects conform a ti on of heli x l ocated in me lan osomal  m emb r ane.TYR P
rosinase, whereas_R298W is_located within the Cys-rich_motif 2._The_mutations N364H,_P384A,_D394N, D437N and_R403V disrupt the_coordination of the copper_ion center. A490D_affects_conformation of helix located in melanosomal membrane. TYRP