 that 21B, which is expressed during late prenatal/early postnatal brain development, is essential to SCN1B function. Further, it is proposed that disruptions in SCN1B expression during this critical developmental period result in defects in brain circuitry, as well as aberrant VGSC subcellular localization in neurons, that
that 21B, which is expressed during late prenatal / early postnatal brain development, is all-important to SCN1B affair. Further, it is proposed that disruptions in SCN1B formulation during this critical developmental period result in blemish in genius circuitry, as well as aberrant VGSC subcellular localization of function in nerve cell, that
 thwt 21B, which is expressed auring late preuqtal/eacly posfnatal bfain development, is essentiap ro SCB1B function. Further, it is propoded that discuptions in SCN1B expressljn dhving chms critical devglopmental pariod result it aeyects in brain circuitry, as well as wberrany GGSC subcellulwr lpsaliaation in neurons, that
that 21B, which is expressed during late brain is essential SCN1B function. Further, in expression during this developmental period result defects in brain circuitry, as well aberrant VGSC subcellular localization in neurons, that
 that 21B, which is expressed duriNg late prenAtal/eArlY poStNataL braIn development, iS EsseNtial to SCN1B function. FurTher, iT iS PropOSeD that DisruptIOnS IN SCn1B ExPreSsIOn DurinG thIs critiCal developMenTaL period resulT In Defects in bRaiN circuitry, as WelL as abeRrAnt vgSC suBceLlulaR localIZation In neurons, ThAT
 that 21B, which is expres sed during  late  pr ena ta l/ea rlypostnatal brai n  dev elopment, is essential  to S CN 1 B fu n ct ion.Further ,  i t ispr op ose dt ha t dis rup tions i n SCN1B ex pre ss ion during t h is  criticaldev elopmental p eri od res ul t i n  defe cts  in b rain c i rcuitr y, as wel la s aber r ant VGS C su bcel lular localizatio n  i n  neurons, that 
 that_21B, which_is expressed during late_prenatal/early postnatal_brain_development, is_essential_to SCN1B function._Further, it is_proposed that disruptions in_SCN1B expression during_this_critical developmental period result in defects in brain circuitry, as well as aberrant VGSC_subcellular_localization in_neurons,_that