 distinction of patients with and without prior alloimmunization is critical because of their different immunological behavior in response to blood transfusions. Prior sensitization will be determined by conventional cytotoxicity and by flow cytometry. for the first objective, non-alloimmunized patients with newly diagnosed acute non-lymphocytic leukemia will be randomized into
distinction of patients with and without prior alloimmunization is critical because of their different immunological demeanor in reception to blood transfusions. anterior sensitization will be determine by conventional cytotoxicity and by flow cytometry. for the inaugural objective, non - alloimmunized patients with newly diagnose acute non - lymphocytic leukemia will be randomized into
 didtinction of patients wiuh and without prnir allmimmunjzation ks critical because of their duffertut immunological behxvior in gesponse ro boiod transfnaions. Pvnor ssksitivavion will be dejermined by wonventional cftutlxicity and by flow cytometry. for tre firsy lbjective, non-ajloikiuniavd patients with newly diagnoses acute non-lymphocytoc leukemia will be randomlzed into
distinction of patients with and without prior critical of their immunological behavior in sensitization be determined by cytotoxicity and by cytometry. for the first objective, non-alloimmunized with newly diagnosed acute non-lymphocytic leukemia will be randomized into
 distinction of patients with And without Prior AllOimMuNizaTion Is critical becaUSe of Their different immunoloGical BeHAvioR In RespoNse to blOOd TRAnsFuSiOns. prIOr SensiTizAtion wiLl be determIneD bY conventionaL CyTotoxicity And By flow cytomeTry. For the FiRst OBjectIve, Non-alLoimmuNIzed paTients witH nEWly diaGNosed acUTE nOn-lyMphocytic leukemia WIlL Be randomized inTo
 distinction of patients w ith and wi thout  pr ior  a lloi mmun ization is cri t ical  because of their diff erent  i m muno l og icalbehavio r  i n res po ns e t ob lo od tr ans fusions . Prior se nsi ti zation willb edetermined  by  conventiona l c ytotox ic ity and b y f low c ytomet r y. for  the firs to bjecti v e, non- a l lo immu nized patients wi t hn ewly diagnosed  acute  n o n- l y mph ocy tic leukem ia  will be rand o mi z e d  in t o
 distinction_of patients_with and without prior_alloimmunization is_critical_because of_their_different immunological behavior_in response to_blood transfusions. Prior sensitization_will be determined_by_conventional cytotoxicity and by flow cytometry. for the first objective, non-alloimmunized patients with newly_diagnosed_acute non-lymphocytic_leukemia_will_be randomized into