 to be activated directly by DAG, whereby subsequent depletion of sarcolemmal PIP2 would prevent endocytosis and favor the expansion of the sarcolemma. Complementary to studies of PI4K2alpha, we will test whether the type 2beta PI4-kinase (PI4K2alpha) is
to be activated directly by DAG, whereby subsequent depletion of sarcolemmal PIP2 would prevent endocytosis and favor the expansion of the sarcolemma. Complementary to report of PI4K2alpha, we will screen whether the type 2beta PI4 - kinase (PI4K2alpha) is
 to be activated directly bn DAG, whereby suywequenv deplefion of rarcolemmal PIP2 would prevenv eneocytisis and favor the expxnsion of the sarxolenna. Complemxhtary to studjcs of 'I4K2alpha, we wilk test whedher the type 2tega PI4-kinase (PI4K2alpha) is
to be activated directly by DAG, whereby of PIP2 would endocytosis and favor Complementary studies of PI4K2alpha, will test whether type 2beta PI4-kinase (PI4K2alpha) is
 to be activated directly by DAg, whereby suBsequEnt DepLeTion Of saRcolemmal PIP2 woULd prEvent endocytosis and favOr the ExPAnsiON oF the sArcolemMA. COMPleMeNtAry To STuDies oF PI4k2alpha, wE will test wHetHeR the type 2beta pi4-kInase (PI4K2alPha) Is
 to be activated directlyby DAG, wh ereby  su bse qu entdepl etion of sarco l emma l PIP2 would prevent e ndocy to s is a n dfavor  the ex p an s i onof  t hesa r co lemma . C ompleme ntary to s tud ie s of PI4K2al p ha , we willtes t whether th e t ype 2b et a P I 4-kin ase  (PI4 K2alph a ) is
 to_be activated_directly by DAG, whereby_subsequent depletion_of_sarcolemmal PIP2_would_prevent endocytosis and_favor the expansion_of the sarcolemma. Complementary_to studies of_PI4K2alpha,_we will test whether the type 2beta PI4-kinase (PI4K2alpha) is