 been shown to suppress A1 expression. Herein, I propose a novel suppressive effect of A1 on HDAC3. My central hypothesis predicts that myeloid A1 protects against retinal IR injury through ODC-mediated suppression of HDAC3. I will be using mice with myeloid-specific deletion of A1, ODC
been shown to suppress A1 expression. Herein, I propose a fresh suppressive consequence of A1 on HDAC3. My central hypothesis predict that myeloid A1 protect against retinal IR injury through ODC - mediated inhibition of HDAC3. I will be using mice with myeloid - specific deletion of A1, ODC
 befn shown to suppress A1 ewpression. Herein, I propmse a hovel suopressive effect of A1 on HDAR3. My centeal hypothesis predictr that myvloid A1 peoterts against retiizl IR iklury fmrougk IDC-mediated sukpression of HDAC3. I will ba jsnng mice with myeloid-specific deletijn of A1, OFC
been shown to suppress A1 expression. Herein, a suppressive effect A1 on HDAC3. myeloid protects against retinal injury through ODC-mediated of HDAC3. I will be using with myeloid-specific deletion of A1, ODC
 been shown to suppress A1 expreSsion. HereiN, I proPosE a nOvEl suPpreSsive effect of A1 ON HDAc3. My central hypothesis prEdictS tHAt myELoId A1 prOtects aGAiNST reTiNaL IR InJUrY throUgh oDC-mediAted suppreSsiOn Of HDAC3. I will bE UsIng mice witH myEloid-specifiC deLetion Of a1, ODc
 been shown to suppress A1  expressio n. He rei n,Iprop osea novel suppre s sive  effect of A1 on HDAC3 . Myce n tral hy pothe sis pre d ic t s  th at  m yel oi d  A 1 pro tec ts agai nst retina l I Rinjury throu g hODC-mediat edsuppressionofHDAC3.  I  wi l l beusi ng mi ce wit h  myelo id-specif ic deleti o n of A1 , OD C
 been_shown to_suppress A1 expression. Herein,_I propose_a_novel suppressive_effect_of A1 on_HDAC3. My central_hypothesis predicts that myeloid_A1 protects against_retinal_IR injury through ODC-mediated suppression of HDAC3. I will be using mice with myeloid-specific_deletion_of A1,_ODC