 prevent the development of CM in patients with sub-clinical infection, and antifungal therapy is required. Yet, the optimal pre-emptive anti-fungal treatment dose and duration necessary to prevent CM in patients with sub-clinical infection have yet to be established. We propose to investigate how practical and effective CRAG screening and
prevent the development of CM in patients with sub - clinical infection, and antifungal therapy is command. so far, the optimal pre - emptive anti - fungal treatment dose and duration necessary to prevent curium in patients with sub - clinical infection hold yet to be established. We project to investigate how practical and effective CRAG screening and
 prfvent the development of CM in patients with snb-clinidal infeztion, and antifungal therapy iw reqyired. Yet, the optimal ore-emptivv anti-funtal ureatment dose anv duration necsdsarv vo prevent CM ik patients fith sub-clinicdl iufection have yet to be established. Re proppsf to investigaje hoe pradnigal and effective CRAG screening and
prevent the development of CM in patients infection, antifungal therapy required. Yet, the and necessary to prevent in patients with infection have yet to be established. propose to investigate how practical and effective CRAG screening and
 prevent the development of CM In patients With sUb-cLinIcAl inFectIon, and antifungAL theRapy is required. Yet, the opTimal PrE-EmptIVe Anti-fUngal trEAtMENt dOsE aNd dUrATiOn necEssAry to prEvent CM in pAtiEnTs with sub-cliNIcAl infectioN haVe yet to be estAblIshed. WE pRopOSe to iNveStigaTe how pRActicaL and effecTiVE CRAG sCReening AND
 prevent the development o f CM in pa tient s w ith  s ub-c lini cal infection, andantifungal therapy isrequi re d . Ye t ,the o ptimalp re - e mpt iv eant i- f un gal t rea tment d ose and du rat io n necessaryt oprevent CM  in  patients wi thsub-cl in ica l  infe cti on ha ve yet to beestablish ed .  We pr o pose to i nv esti gate how practica l  a n d effective CR AG scr ee n in g and 
 prevent_the development_of CM in patients_with sub-clinical_infection,_and antifungal_therapy_is required. Yet,_the optimal pre-emptive_anti-fungal treatment dose and_duration necessary to_prevent_CM in patients with sub-clinical infection have yet to be established. We propose to_investigate_how practical_and_effective_CRAG screening and