 as well as monocyte progenitors to release enhanced amounts of cytokine in response to bacterial endotoxin. Using both tissue macrophage and those derived from bone marrow progenitors, cytokine responses to endotoxin as well as phagocytosis and chemotaxis will be determined in mice with denervated compared to neural intact bone marrow. Having established the role of
as well as monocyte progenitors to release enhanced amounts of cytokine in reception to bacterial endotoxin. use both tissue macrophage and those derived from bone marrow progenitors, cytokine reaction to endotoxin as well as phagocytosis and chemotaxis will be determined in mouse with denervated compare to neural integral bone marrow. Having established the function of
 as well as monocyte progenltors to release enhancxd amouhts of chtokine in response to bactecial endoujxin. Using both tirsue macrlphage abd tiose derived from bone marrow lvogenntirs, cytokine rgsponses to andotoxin as walu cs phagocytosis and chemotaxis will fe detetmlned in mice wyth cqnerbated compared to neural intact bohe marrmw. Having estsblished the role of
as well as monocyte progenitors to release of in response bacterial endotoxin. Using derived bone marrow progenitors, responses to endotoxin well as phagocytosis and chemotaxis will determined in mice with denervated compared to neural intact bone marrow. Having established role of
 as well as monocyte progenitoRs to releasE enhaNceD amOuNts oF cytOkine in responsE To baCterial endotoxin. Using bOth tiSsUE macROpHage aNd those DErIVEd fRoM bOne MaRRoW progEniTors, cytOkine respoNseS tO endotoxin as WElL as phagocyTosIs and chemotaXis Will be DeTerMIned iN miCe witH denerVAted coMpared to nEuRAl intaCT bone maRROw. haviNg established the rOLe OF
 as well as monocyte proge nitors torelea seenh an cedamou nts of cytokin e  inresponse to bacterialendot ox i n. U s in g bot h tissu e  m a c rop ha ge  an dt ho se de riv ed from  bone marr owpr ogenitors, c y to kine respo nse s to endotox inas wel lasp hagoc yto sis a nd che m otaxis  will bede t ermine d  in mic e wi th d enervated compare d  t o  neural intact  bonema r ro w .  Ha vin g establis he d the role of 
 as_well as_monocyte progenitors to release_enhanced amounts_of_cytokine in_response_to bacterial endotoxin._Using both tissue_macrophage and those derived_from bone marrow_progenitors,_cytokine responses to endotoxin as well as phagocytosis and chemotaxis will be determined in_mice_with denervated_compared_to_neural intact bone marrow. Having_established the role of