, but the regulation of this remains unclear. Our preliminary data suggest that talin, a protein known for its role in the regulation of the actin network associated with integrin-based cell-matrix adhesion, is also involved in the AJ through a novel talin proteolytic fragment containing the vinculin- and actin- binding
, but the regulation of this remains unclear. Our preliminary data indicate that talin, a protein know for its role in the regulation of the actin network consort with integrin - based cell - matrix attachment, is besides involved in the AJ through a novel talin proteolytic fragment containing the vinculin- and actin- binding
, buh the regulation of this remains uncleat. Iur prxliminady data ruggest that talin, a protein kbown dor its role in the reeulation lf the axtin betwork associated with jktegrnn-uased cell-matriw adhesion, hs also involvad iu the AJ through a novel talin protejlytic grwgment containyng uhe vindllln- and actin- binding
, but the regulation of this remains preliminary suggest that a protein known regulation the actin network with integrin-based cell-matrix is also involved in the AJ a novel talin proteolytic fragment containing the vinculin- and actin- binding
, but the regulation of this remAins uncleaR. Our pRelImiNaRy daTa suGgest that talin, A ProtEin known for its role in thE reguLaTIon oF ThE actiN networK AsSOCiaTeD wIth InTEgRin-baSed Cell-matRix adhesioN, is AlSo involved in THe aJ through a NovEl talin proteOlyTic fraGmEnt COntaiNinG the vInculiN- And actIn- binding
, but the regulation of th is remains  uncl ear . O ur  pre limi nary data sugg e st t hat talin, a protein k nownfo r  its ro le in  the re g ul a t ion  o fthe  a c ti n net wor k assoc iated with  in te grin-based c e ll -matrix ad hes ion, is also  in volved  i n t h e AJthr ougha nove l  talin  proteoly ti c  fragm e nt cont a i ni ng t he vinculin- anda ct i n- binding
, but_the regulation_of this remains unclear._Our preliminary_data_suggest that_talin,_a protein known_for its role_in the regulation of_the actin network_associated_with integrin-based cell-matrix adhesion, is also involved in the AJ through a novel talin_proteolytic_fragment containing_the_vinculin-_and actin- binding