 begins with the systematic analysis of insulin signaling. After over 30 years of intensive research in the pursuit of relevant protein kinases, Akt/PKB has emerged as the only serine/threonine protein kinases definitively established as a mediator of insulin's regulation of important metabolic targets. The activity of Akt/PKB depends on
begins with the systematic analysis of insulin signaling. After over 30 days of intensive inquiry in the pursuit of relevant protein kinases, Akt / PKB has emerge as the alone serine / threonine protein kinases definitively established as a mediator of insulin's rule of important metabolic targets. The activity of Akt / PKB depend on
 behins with the systematic analysis of insulin smgnalinf. After uver 30 years of intensive resxarcy in uke pursuit of relevavt proteij kinasew, Aku/PKB has emerged ea the okjy ssvine/tkrxonine protein linases dexinitively estdbuidhed as a mediator of insulin's regujation pf important metwbolpc tarfvtw. The activity of Akt/PKB depehds on
begins with the systematic analysis of insulin over years of research in the Akt/PKB emerged as the serine/threonine protein kinases established as a mediator of insulin's of important metabolic targets. The activity of Akt/PKB depends on
 begins with the systematic anAlysis of inSulin SigNalInG. AftEr ovEr 30 years of intenSIve rEsearch in the pursuit of rElevaNt PRoteIN kInaseS, Akt/PKB HAs EMErgEd As The OnLY sErine/ThrEonine pRotein kinaSes DeFinitively esTAbLished as a mEdiAtor of insuliN's rEgulatIoN of IMportAnt MetabOlic taRGets. ThE activity Of aKt/PKB dEPends on
 begins with the systemati c analysis  of i nsu lin  s igna ling . After over 3 0  yea rs of intensive resear ch in  t h e pu r su it of  releva n tp r ote in  k ina se s ,Akt/P KBhas eme rged as th e o nl y serine/thr e on ine protei n k inases defin iti vely e st abl i shedasa med iatoro f insu lin's reg ul a tion o f  import a n tmeta bolic targets. Th e  a c tivity of Akt/ PKB de pe n ds o n
 begins_with the_systematic analysis of insulin_signaling. After_over_30 years_of_intensive research in_the pursuit of_relevant protein kinases, Akt/PKB_has emerged as_the_only serine/threonine protein kinases definitively established as a mediator of insulin's regulation of important_metabolic_targets. The_activity_of_Akt/PKB depends on