 access natural products, and has focused our efforts on secondary metabolite families that appear to covalently modify their targets as the basis for their phenotypic effects. Our chemical syntheses are deliberately concise and easily-scaled to enable subsequent investigation into reactivity and biological activity. The current application significantly advances these efforts, provides compelling preliminary data
access natural products, and has focused our efforts on junior-grade metabolite class that appear to covalently modify their target as the footing for their phenotypic effects. Our chemical syntheses are intentionally concise and easily - scaled to enable subsequent probe into responsiveness and biological activity. The current application importantly advances these efforts, provide compelling preliminary datum
 acfess natural products, ana has focused oor efforvs on sscondary metabolite families that ap'ear to civalently modify their targets ws the bqsis dor their 'genotyple effsgts. Obr chemical syntmeses are daliberately cotcksz and easily-scaled to enable subsequqnt invrshigation into teactpvyty znd biological activity. The currenf applibation significanyly advances these efforts, progides compelling pgeliminary eata
access natural products, and has focused our secondary families that to covalently modify for phenotypic effects. Our syntheses are deliberately and easily-scaled to enable subsequent investigation reactivity and biological activity. The current application significantly advances these efforts, provides compelling data
 access natural products, and hAs focused oUr effOrtS on SeCondAry mEtabolite familIEs thAt appear to covalently moDify tHeIR tarGEtS as thE basis fOR tHEIr pHeNoTypIc EFfEcts. OUr cHemical Syntheses aRe dElIberately conCIsE and easily-ScaLed to enable sUbsEquent InVesTIgatiOn iNto reActiviTY and biOlogical aCtIVity. ThE Current APPlIcatIon significantly aDVaNCes these effortS, proviDeS CoMPEllIng PreliminarY dAta
 access natural products,and has fo cused  ou r e ff orts  onsecondary meta b olit e families that appear  to c ov a lent l ymodif y their ta r g ets  a sthe  b a si s for  th eir phe notypic ef fec ts . Our chemic a lsynthesesare  deliberatel y c oncise  a nde asily -sc aledto ena b le sub sequent i nv e stigat i on into r ea ctiv ity and biologica l  a c tivity. The cu rrentap p li c a tio n s ignificant ly  adva n ces the s ee f f ort s , provides co mpelling pr e lim inaryda ta
 access_natural products,_and has focused our_efforts on_secondary_metabolite families_that_appear to covalently_modify their targets_as the basis for_their phenotypic effects._Our_chemical syntheses are deliberately concise and easily-scaled to enable subsequent investigation into reactivity and_biological_activity. The_current_application_significantly advances these efforts, provides_compelling preliminary data