 functional capacities of these cells, including cytokines produced, will be characterized extensively. We will next test the different types of DC for efficient localization in T cell areas of lymph nodes after intranodal injection. Finally, we will test in vivo the ability of different DC types to stimulate polarized CD4 T cell responses to antigens and
functional capacities of these cells, including cytokine produce, will be characterized extensively. We will next test the unlike types of DC for effective localization in T cellular telephone areas of lymph nodes after intranodal injection. Finally, we will screen in vivo the ability of different DC types to provoke polarized CD4 T cellular telephone responses to antigens and
 fujctional capacities of tmese cells, inclubung cyvokines producea, will be characterized exteisivwly. Wt will next test thd differejt types of VC for efficient localization jk T czlo areas of lymkh nodes aftar intranodal hngeetion. Finally, we will test in vivo tre abilotj of different DC uypqs tk stimulate polarized CD4 T cell reaponses to antigens snd
functional capacities of these cells, including cytokines be extensively. We next test the efficient in T cell of lymph nodes intranodal injection. Finally, we will test vivo the ability of different DC types to stimulate polarized CD4 T cell to antigens and
 functional capacities of theSe cells, incLudinG cyTokInEs prOducEd, will be characTErizEd extensively. We will nexT test ThE DiffEReNt typEs of DC fOR eFFIciEnT lOcaLiZAtIon in t ceLl areas Of lymph nodEs aFtEr intranodal INjEction. FinaLly, We will test in VivO the abIlIty OF diffEreNt DC tYpes to STimulaTe polarizEd cd4 T cell REsponseS TO aNtigEns and
 functional capacities ofthese cell s, in clu din gcyto kine s produced, wi l l be  characterized extensi vely.  W e  wil l  n ext t est the di f f ere nt  t ype so fDC fo r e fficien t localiza tio nin T cell ar e as  of lymphnod es after int ran odal i nj ect i on. F ina lly,we wil l  testin vivo t he abilit y  of dif f e re nt D C types to stimul a te polarized CD4T cell  r e sp o n ses  to  antigensan d
 functional_capacities of_these cells, including cytokines_produced, will_be_characterized extensively._We_will next test_the different types_of DC for efficient_localization in T_cell_areas of lymph nodes after intranodal injection. Finally, we will test in vivo the_ability_of different_DC_types_to stimulate polarized CD4 T_cell responses to antigens and