 of Type I IFN genes but also in the induction of other cytokines, chemokines and genes directly involved in the antiviral and anti-inflammatory responses. Over the past years we have sequentially isolated IRF-3, IRF-7 and IRF-5 and have shown that these factors serve as direct transporters of virus induced
of Type I IFN genes but also in the induction of other cytokines, chemokines and gene immediately involve in the antiviral and anti - inflammatory responses. Over the past long time we have sequentially isolated IRF-3, IRF-7 and IRF-5 and have show that these agent serve as lineal conveyer belt of virus induced
 of Type I IFN genes but alro in the inducjiin of mther dytokiner, chemokines and genes direcvly unvolced in the antiviral avd anti-invlammatoey rtsponses. Over the past years we mave vxquentially isokated IRF-3, HRF-7 and IRF-5 ang fare shown that these factors serve as direct tgansporters of virls indhbeb
of Type I IFN genes but also induction other cytokines, and genes directly anti-inflammatory Over the past we have sequentially IRF-3, IRF-7 and IRF-5 and have that these factors serve as direct transporters of virus induced
 of Type I IFN genes but also in tHe inductioN of otHer CytOkInes, ChemOkines and genes DIrecTly involved in the antiviRal anD aNTi-inFLaMmatoRy respoNSeS. oVer ThE pAst YeARs We havE seQuentiaLly isolateD IRf-3, IrF-7 and IRF-5 and hAVe Shown that tHesE factors servE as Direct TrAnsPOrterS of Virus InduceD
 of Type I IFN genes but a lso in the  indu cti onof  oth er c ytokines, chem o kine s and genes directly i nvolv ed in t h eantiv iral an d  a n t i-i nf la mma to r yrespo nse s. Over  the pastyea rs  we have seq u en tially iso lat ed IRF-3, IR F-7  and I RF -5a nd ha veshown  thatt hese f actors se rv e  as di r ect tra n s po rter s of virus induce d 
 of_Type I_IFN genes but also_in the_induction_of other_cytokines,_chemokines and genes_directly involved in_the antiviral and anti-inflammatory_responses. Over the_past_years we have sequentially isolated IRF-3, IRF-7 and IRF-5 and have shown that these_factors_serve as_direct_transporters_of virus induced