 aggravate AIDS-associated CNS dysfunctions. The results obtained in this proposal will allow the generation of data on direct effects of the drug on cells, relative susceptibility of different cell types to direct actions, and on pathways, aiming a future R01 application on modulation of oxidative stress in Meth abuse in vivo. These will lead
aggravate AIDS - associated CNS dysfunctions. The result prevail in this proposal will allow the generation of datum on direct effects of the drug on cells, proportional susceptibility of unlike cell types to direct actions, and on pathways, calculate a future R01 application on modulation of oxidative tension in Meth abuse in vivo. These will lead
 aghravate AIDS-associated CKS dysfunctions. Jhw resunts obfained iv this proposal will allow tie gwneraupon of data on direct effects lf the deug ib cells, relative smfcepflbilicy of different gell types do direct actimnr, cnd on pathways, aiming a future R01 ap[licatipn on modulation of pvidafpvt stress in Meth abuse in vivo. Thsse wiln lead
aggravate AIDS-associated CNS dysfunctions. The results obtained proposal allow the of data on on relative susceptibility of cell types to actions, and on pathways, aiming a R01 application on modulation of oxidative stress in Meth abuse in vivo. These lead
 aggravate AIDS-associated CNs dysfunctiOns. ThE reSulTs ObtaIned In this proposal WIll aLlow the generation of datA on diReCT effECtS of thE drug on CElLS, RelAtIvE suScEPtIbiliTy oF differEnt cell typEs tO dIrect actions, ANd On pathways, AimIng a future R01 aPplIcatioN oN moDUlatiOn oF oxidAtive sTRess in meth abuse In VIvo. TheSE will leAD
 aggravate AIDS-associated  CNS dysfu nctio ns.  Th eresu ltsobtained in th i s pr oposal will allow thegener at i on o f  d ata o n direc t  e f f ect sof  th ed ru g oncel ls, rel ative susc ept ib ility of dif f er ent cell t ype s to directact ions,an d o n  path way s, ai ming a future  R01 appl ic a tion o n  modula t i on  ofoxidative stressi nM eth abuse in v ivo. T he s ew i lllea d
 aggravate_AIDS-associated CNS_dysfunctions. The results obtained_in this_proposal_will allow_the_generation of data_on direct effects_of the drug on_cells, relative susceptibility_of_different cell types to direct actions, and on pathways, aiming a future R01 application_on_modulation of_oxidative_stress_in Meth abuse in vivo._These will lead