 of cohesion during aging causes defects in chromosome segregation in older eggs. In addition, we will will use genetic and proteomic approaches to identify gene products that influence age-dependent nondisjunction. We have described two dsRNA viruses (L-A and L-BC) and two ssRNA replicons (20S
of cohesion during aging causes defects in chromosome segregation in old egg. In addition, we will will use genetic and proteomic approach to identify gene products that influence historic period - dependent nondisjunction. We have described two dsRNA virus (L - A and L - BC) and two ssRNA replicons (20S
 of cohesion during aging cxuses defects iu chrommsome aegregatkon in older eggs. In additioi, we will will use genetic and oroteomic approacyes uo identify gene 'doducts that jkflueucx age-dependent kondisjuncthon. We have devcfiyed two dsRNA viruses (L-A and L-BC) and two ssTNW replicons (20S
of cohesion during aging causes defects in in eggs. In we will will to gene products that age-dependent nondisjunction. We described two dsRNA viruses (L-A and and two ssRNA replicons (20S
 of cohesion during aging causEs defects iN chroMosOme SeGregAtioN in older eggs. In ADditIon, we will will use genetiC and pRoTEomiC ApProacHes to idENtIFY geNe PrOduCtS ThAt infLueNce age-dEpendent noNdiSjUnction. We havE DeScribed two DsRnA viruses (L-A aNd L-bC) and tWo SsRna replIcoNs (20S
 of cohesion during agingcauses def ectsinchr om osom e se gregation in o l dereggs. In addition, wewillwi l l us e  g eneti c and p r ot e o mic  a pp roa ch e sto id ent ify gen e products  th at  influence a g e- dependentnon disjunction.  We  havede scr i bed t wodsRNA  virus e s (L-A  and L-BC )a nd two ssRNA r e p li cons  (20S
 of_cohesion during_aging causes defects in_chromosome segregation_in_older eggs._In_addition, we will_will use genetic_and proteomic approaches to_identify gene products_that_influence age-dependent nondisjunction. We have described two dsRNA viruses (L-A and L-BC) and two_ssRNA_replicons (20S