 reflect changes in protein secretion and shedding from renal tubular cells and other sources. We predict that these changes will vary with onset, duration and severity of the obstruction. In our previous work, we have demonstrated our ability to use state-of-the-art mass spectrometric and proteomic approaches to identify proteins in the urinary
reflect changes in protein secretion and shedding from renal tubular cell and early sources. We predict that these change will deviate with onset, duration and severity of the obstacle. In our previous work, we have demonstrated our ability to practice department of state - of - the - art bulk spectrometric and proteomic approaches to identify protein in the urinary
 revlect changes in protein secretion and sheddinj from denal tucular cells and other sourced. Qe prtbict that these chanees will nary with onstt, duration and sxberity of the lbstxurtion. In our prgvious work, fe have demonsdrxtzd our ability to use state-of-the-art iass sprchrometric and krotepiic zipvoaches to identify proteins in fhe uriiary
reflect changes in protein secretion and shedding tubular and other We predict that onset, and severity of obstruction. In our work, we have demonstrated our ability use state-of-the-art mass spectrometric and proteomic approaches to identify proteins in the urinary
 reflect changes in protein seCretion and SheddIng FroM rEnal TubuLar cells and othER souRces. We predict that these ChangEs WIll vARy With oNset, durATiON And SeVeRitY oF ThE obstRucTion. In oUr previous WorK, wE have demonstRAtEd our abiliTy tO use state-of-tHe-aRt mass SpEctROmetrIc aNd proTeomic APproacHes to idenTiFY proteINs in the URInAry
 reflect changes in protei n secretio n and  sh edd in g fr om r enal tubular c e llsand other sources. Wepredi ct that th ese c hangesw il l var ywi thon s et , dur ati on andseverity o f t he  obstruction .  I n our prev iou s work, we h ave  demon st rat e d our  ab ility  to us e  state -of-the-a rt mass s p ectrome t r ic  and  proteomic approa c he s  to identify p rotein si nt h e u rin ary
 reflect_changes in_protein secretion and shedding_from renal_tubular_cells and_other_sources. We predict_that these changes_will vary with onset,_duration and severity_of_the obstruction. In our previous work, we have demonstrated our ability to use state-of-the-art_mass_spectrometric and_proteomic_approaches_to identify proteins in the_urinary