 inflammation thereafter leads to spinal ankylosis and poorer long-term health outcomes. We will test this model in two stages. First, we will identify genetic markers associated with worse radiological outcomes, greater functional disability, work disability and need for total hip arthroplasty in a retrospective cohort study of 400 patients with AS of 20 years
inflammation thereafter leads to spinal ankylosis and poorer retentive - condition health outcomes. We will test this model in two degree. First, we will identify genic marker associated with worse radiological outcomes, greater running disability, work disability and need for total hip arthroplasty in a retrospective age group study of 400 patients with AS of 20 days
 invlammation thereafter lexds to spinal aujylosiv and loorer lung-term health outcomes. We wmll rest ukis model in two staees. First, we will ideitify genetic maciers associatsf wich worse radiolonical outcokes, greater futcgilnal disability, work disability and need fpr total hip artrropkwsty pn a retrospective cohort study of 400 pauients with AS of 20 years
inflammation thereafter leads to spinal ankylosis and health We will this model in identify markers associated with radiological outcomes, greater disability, work disability and need for hip arthroplasty in a retrospective cohort study of 400 patients with AS of years
 inflammation thereafter leaDs to spinal AnkylOsiS anD pOoreR lonG-term health outCOmes. we will test this model in tWo staGeS. firsT, We Will iDentify GEnETIc mArKeRs aSsOCiAted wIth Worse raDiological OutCoMes, greater fuNCtIonal disabIliTy, work disabiLitY and neEd For TOtal hIp aRthroPlasty IN a retrOspective CoHOrt stuDY of 400 patiENTs With aS of 20 years
 inflammation thereafter l eads to sp inalank ylo si s an d po orer long-term heal th outcomes. We will t est t hi s  mod e lin tw o stage s .F i rst ,we  wi ll id entif y g eneticmarkers as soc ia ted with wor s eradiologic aloutcomes, gr eat er fun ct ion a l dis abi lity,  workd isabil ity and n ee d  for t o tal hip a rt hrop lasty in a retros p ec t ive cohort stu dy of40 0  p a t ien tswith AS of  2 0 yea r s
 inflammation_thereafter leads_to spinal ankylosis and_poorer long-term_health_outcomes. We_will_test this model_in two stages._First, we will identify_genetic markers associated_with_worse radiological outcomes, greater functional disability, work disability and need for total hip arthroplasty_in_a retrospective_cohort_study_of 400 patients with AS_of 20 years