 accessibility and known microbial composition. Specific Aim 1 will examine the effects of 3 systemically administered antibiotics on the microbial composition of subgingival biofilms in adult humans with periodontitis. All subjects will receive scaling and root planing and will be randomly assigned to one of 4 groups of 36 subjects each receiving one of do
accessibility and known microbial composition. Specific Aim 1 will examine the effect of 3 systemically distribute antibiotics on the microbial composition of subgingival biofilms in adult humans with periodontal disease. All subjects will receive scaling and root planing and will be randomly put to one of 4 groups of 36 subjects each meet one of do
 acfessibility and known migrobial compositnin. Sperific Ajm 1 will examine the effects of 3 sysvemixally administered antibiotkcs on thv microbiql cinposition of subgikyival niofinns in adult hukans with [eriodontitis. Dlu dubjects will receive scaling and rjot plamijg and will be rancjmly assigned to one of 4 groups of 36 sugjects tach receiving one of do
accessibility and known microbial composition. Specific Aim examine effects of systemically administered antibiotics subgingival in adult humans periodontitis. All subjects receive scaling and root planing and be randomly assigned to one of 4 groups of 36 subjects each receiving of do
 accessibility and known micrObial compoSitioN. SpEciFiC Aim 1 Will Examine the effeCTs of 3 Systemically administerEd antIbIOticS On The miCrobial COmPOSitIoN oF suBgINgIval bIofIlms in aDult humans WitH pEriodontitis. aLl Subjects wiLl rEceive scalinG anD root pLaNinG And wiLl bE randOmly asSIgned tO one of 4 groUpS Of 36 subjECts each RECeIvinG one of do
 accessibility and known m icrobial c ompos iti on.  S peci ficAim 1 will exa m inethe effects of 3 syste mical ly admi n is tered  antibi o ti c s  on  t he  mi cr o bi al co mpo sitionof subging iva lbiofilms ina du lt humanswit h periodonti tis . Allsu bje c ts wi llrecei ve sca l ing an d root pl an i ng and will be r an doml y assigned to one of 4 groups of 36  subje ct s  e a c h r ece iving oneof  do
 accessibility_and known_microbial composition. Specific Aim_1 will_examine_the effects_of_3 systemically administered_antibiotics on the_microbial composition of subgingival_biofilms in adult_humans_with periodontitis. All subjects will receive scaling and root planing and will be randomly_assigned_to one_of_4_groups of 36 subjects each_receiving one of do