. The mechanisms underlying the virulence differences between serotypes are not known but may involve both the polysaccharide structures and other factors in the genetic background in which they are expressed. Molecular genetic studies have identified a common organization among the different S. pneumoniae capsule loci. This organization permits the exchange of capsular serotypes during transformation,
. The mechanisms underlying the virulence differences between serotypes are not known but may imply both the polysaccharide structure and other factors in the genetic backdrop in which they are expressed. Molecular genetic study have identified a common arrangement among the different S. pneumoniae capsule locus. This organization permits the substitution of capsular serotypes during transformation,
. Thf mechanisms underlying uhe virulence difywrencev betwsen serogypes are not known but may mnvoove bith the polysaccharide structurvs and otyer hactors in the gxhetic backgrohkd in xhich they are gxpressed. Monecular genetiw rtbdies have identified a common organyzation along the diffetent X. pnehmoniae capsule loci. This organizafion pegmits the exchangr of capsular serotypes duging transformation,
. The mechanisms underlying the virulence differences are known but involve both the in genetic background in they are expressed. genetic studies have identified a common among the different S. pneumoniae capsule loci. This organization permits the exchange of serotypes during transformation,
. The mechanisms underlying thE virulence DiffeRenCes BeTweeN serOtypes are not knOWn buT may involve both the polySacchArIDe stRUcTures And otheR FaCTOrs In ThE geNeTIc BackgRouNd in whiCh they are eXprEsSed. Molecular GEnEtic studieS haVe identified A coMmon orGaNizATion aMonG the dIffereNT S. pneuMoniae capSuLE loci. THIs organIZAtIon pErmits the exchange OF cAPsular serotypeS durinG tRAnSFOrmAtiOn,
. The mechanisms underlyin g the viru lence  di ffe re nces  bet ween serotypes arenot known but may invo lve b ot h  the po lysac charide st r u ctu re sand  o t he r fac tor s in th e geneticbac kg round in whi c hthey are e xpr essed. Molec ula r gene ti c s t udies  ha ve id entifi e d a co mmon orga ni z ationa mong th e di ffer ent S. pneumoniae ca p sule loci. Thi s orga ni z at i o n p erm its the ex ch angeo f capsu l ar s e rot y pes during tr ansformatio n ,
. The_mechanisms underlying_the virulence differences between_serotypes are_not_known but_may_involve both the_polysaccharide structures and_other factors in the_genetic background in_which_they are expressed. Molecular genetic studies have identified a common organization among the different_S._pneumoniae capsule_loci._This_organization permits the exchange of_capsular serotypes during transformation,