 of proteins, polypeptides and lipoproteins across cells and basement membranes. The studies will be done on isolated segments of renal tubules employing in vitro and in situ microperfusion methods and electron microscopy. Functional, quantitative data on the absorption and transport of various macromolecular substances will be directly correlated with fine structural changes at the
of proteins, polypeptides and lipoproteins across cells and basement membrane. The cogitation will be done on sequester segment of renal tubules hire in vitro and in situ microperfusion method acting and electron microscopy. Functional, quantitative datum on the concentration and transport of versatile macromolecular substances will be directly correlate with all right structural changes at the
 of proteins, polypeptides akd lipoproteins cxross rells ahd basemdnt membranes. The studies wipl be dine on isolated segmengs of renwl tubulws enploying in vitro akb in altu mnccoperfusion metmods and elactron microscmph. Yunctional, quantitative data on the wbsorptooj and transporj of nawioua macromolecular substances will bs direculy correlated witn fine structural changes wt tje
of proteins, polypeptides and lipoproteins across cells membranes. studies will done on isolated in and in situ methods and electron Functional, quantitative data on the absorption transport of various macromolecular substances will be directly correlated with fine structural changes the
 of proteins, polypeptides and LipoproteiNs acrOss CelLs And bAsemEnt membranes. ThE StudIes will be done on isolateD segmEnTS of rENaL tubuLes emplOYiNG In vItRo And In SItU micrOpeRfusion Methods and EleCtRon microscopY. fuNctional, quAntItative data oN thE absorPtIon ANd traNspOrt of VariouS MacromOlecular sUbSTances WIll be diRECtLy coRrelated with fine sTRuCTural changes at The
 of proteins, polypeptides  and lipop rotei nsacr os s ce llsand basement m e mbra nes. The studies willbe do ne on i s ol atedsegment s  o f ren al  t ubu le s  e mploy ing  in vit ro and insit umicroperfusi o nmethods an d e lectron micr osc opy. F un cti o nal,qua ntita tive d a ta onthe absor pt i on and transpo r t  o f va rious macromolecu l ar substances wil l be d ir e ct l y  co rre lated with  f ine s t ructura l  c h a n ges at the
 of_proteins, polypeptides_and lipoproteins across cells_and basement_membranes._The studies_will_be done on_isolated segments of_renal tubules employing in_vitro and in_situ_microperfusion methods and electron microscopy. Functional, quantitative data on the absorption and transport of_various_macromolecular substances_will_be_directly correlated with fine structural_changes at the