, in retinal pigmented epithelial cells (RPE) and lens epithelial cells (LEC) iron regulates the activity of the transcription factor, hypoxia-inducible factor, which in turn regulates the synthesis of dozens of proteins. Our preliminary data indicate that hypoxic conditions stimulate glutamate release, another critically important observation since hypoxic conditions
, in retinal pigmented epithelial cells (RPE) and lens epithelial cells (LEC) iron regulates the natural process of the arrangement factor, hypoxia - inducible factor, which in turn regulate the synthesis of dozens of protein. Our preliminary data indicate that hypoxic conditions induce glutamate release, another critically important notice since hypoxic conditions
, in retinal pigmented epithtlial cells (RPE) aue lens epithslial ceuls (LEC) iron regulates the artivuty od the transcription faztor, hypoqia-inducivle hactor, which in vhrn regmjatea the wynthesis of dpzens of psoteins. Our pralkmnnary data indicate that hypoxic conqitions shimulate glutaiate welezse, another critically important ogservatpon since hypoxic conditions
, in retinal pigmented epithelial cells (RPE) epithelial (LEC) iron the activity of which turn regulates the of dozens of Our preliminary data indicate that hypoxic stimulate glutamate release, another critically important observation since hypoxic conditions
, in retinal pigmented epithelIal cells (RPe) and lEns EpiThEliaL celLs (LEC) iron regulATes tHe activity of the transcrIptioN fACtor, HYpOxia-iNduciblE FaCTOr, wHiCh In tUrN ReGulatEs tHe synthEsis of dozeNs oF pRoteins. Our prELiMinary data IndIcate that hypOxiC condiTiOns STimulAte GlutaMate reLEase, anOther critIcALly impORtant obSERvAtioN since hypoxic condITiONs
, in retinal pigmented epi thelial ce lls ( RPE ) a nd  len s ep ithelial cells (LEC ) iron regulates the a ctivi ty of t h etrans criptio n  f a c tor ,hy pox ia - in ducib lefactor,  which intur nregulates th e  s ynthesis o f d ozens of pro tei ns. Ou rpre l imina rydataindica t e that  hypoxicco n dition s  stimul a t eglut amate release, an o th e r critically i mporta nt ob s e rva tio n since hy po xic c o ndition s 
, in_retinal pigmented_epithelial cells (RPE) and_lens epithelial_cells_(LEC) iron_regulates_the activity of_the transcription factor,_hypoxia-inducible factor, which in_turn regulates the_synthesis_of dozens of proteins. Our preliminary data indicate that hypoxic conditions stimulate glutamate release,_another_critically important_observation_since_hypoxic conditions