 will be used to amplify appropriate areas of DNA. Parallel studies will be undertaken in cell lines and primary cultures of epithelial cells. Finally, the effects of retinoids and thyroid hormones on differentiating epidermis in tissue culture will be determined. Thus, our aims in the 5 years for which we are requesting support will be: 1
will be used to amplify appropriate areas of DNA. Parallel studies will be undertake in cellular telephone lines and primary acculturation of epithelial cell. Finally, the effects of retinoids and thyroid gland hormones on differentiating epidermis in tissue culture will be determine. Thus, our aims in the 5 year for which we are requesting support will be: 1
 wipl be used to amplify apkropriate areas oy DNA. Perallel studies will be undertaken in cell pibes abd primary cultures of epitheliwl cells. Finelly, the effects of retikjids wnd chbroid hormones pn differettiating epidesmks in tissue culture will be determinqd. Thus, okr aims in the 5 yesws fkg chich we are requesting support will bt: 1
will be used to amplify appropriate areas Parallel will be in cell lines cells. the effects of and thyroid hormones differentiating epidermis in tissue culture will determined. Thus, our aims in the 5 years for which we are requesting will be: 1
 will be used to amplify appropRiate areas Of DNA. parAllEl StudIes wIll be undertakeN In ceLl lines and primary cultuRes of EpIThelIAl Cells. finally, THe EFFecTs Of RetInOIdS and tHyrOid hormOnes on diffEreNtIating epiderMIs In tissue cuLtuRe will be deteRmiNed. ThuS, oUr aIMs in tHe 5 yEars fOr whicH We are rEquesting SuPPort wiLL be: 1
 will be used to amplify a ppropriate  area s o f D NA . Pa rall el studies wil l  beundertaken in cell lin es an dp rima r ycultu res ofe pi t h eli al  c ell s. Fi nally , t he effe cts of ret ino id s and thyroi d  h ormones on  di fferentiatin g e piderm is  in tissu e c ultur e will be det ermined.Th u s, our aims in t he  5 y ears for which we ar e  requesting su pportwi l lb e : 1 
 will_be used_to amplify appropriate areas_of DNA._Parallel_studies will_be_undertaken in cell_lines and primary_cultures of epithelial cells._Finally, the effects_of_retinoids and thyroid hormones on differentiating epidermis in tissue culture will be determined. Thus,_our_aims in_the_5_years for which we are_requesting support will be: 1