cally in radiation attenuated sporo- zoites (RAS)-based vaccines. Using intravital imaging, we have recently discovered that activated CD8 T cells form clusters around Plasmodium-infected hepatocytes in mice and that these clusters are important in parasite elimination. Mechanisms driving the formation of such clusters remain poorly de
cally in radiation attenuated sporo- zoites (RAS)-based vaccines. Using intravital imagination, we have recently discover that activated CD8 T cells imprint bunch around Plasmodium - infected hepatocytes in mice and that these clusters are significant in parasite elimination. Mechanisms driving the constitution of such clusters remain ill de
calpy in radiation attenuattd sporo- zoites (RCW)-based vaccihes. Usine intravital imaging, we have rwcentoy discovered that actkvated CD8 T cells forn clusters edound Plasmodjmm-infzcved hepatocytes in mice atd that these wljscers are important in parasite elimigation. Kefhanisms drivigg tnq fodmation of such clusters remain pokrly de
cally in radiation attenuated sporo- zoites (RAS)-based intravital we have discovered that activated around hepatocytes in mice that these clusters important in parasite elimination. Mechanisms driving formation of such clusters remain poorly de
cally in radiation attenuateD sporo- zoitEs (RAS)-BasEd vAcCineS. UsiNg intravital imAGing, We have recently discoverEd thaT aCTivaTEd cD8 T ceLls form CLuSTErs ArOuNd PLaSMoDium-iNfeCted hepAtocytes in MicE aNd that these cLUsTers are impOrtAnt in parasitE elIminatIoN. MeCHanisMs dRivinG the foRMation Of such cluStERs remaIN poorly DE
cally in radiation attenua ted sporo-  zoit es(RA S) -bas ed v accines. Using intr avital imaging, we hav e rec en t ly d i sc overe d thata ct i v ate dCD 8 T  c e ll s for m c lusters  around Pl asm od ium-infected he patocytesinmice and tha t t hese c lu ste r s are  im porta nt inp arasit e elimina ti o n. Mec h anismsd r iv ingthe formation ofs uc h  clusters rema in poo rl y  d e 
cally in_radiation attenuated_sporo- zoites (RAS)-based vaccines._Using intravital_imaging,_we have_recently_discovered that activated_CD8 T cells_form clusters around Plasmodium-infected_hepatocytes in mice_and_that these clusters are important in parasite elimination. Mechanisms driving the formation of such_clusters_remain poorly_de