 M. tuberculosis. In the Aim 2, we will study the relationship between PE and PPE protein secretion, post-translational modification and the immunogenicity of these proteins. This work will refine our model of how PE and PPE proteins generate antigenic diversity in M. tuberculosis. Together, these data will dramatically increase
M. tuberculosis. In the Aim 2, we will study the relationship between PE and PPE protein secretion, post - translational modification and the immunogenicity of these proteins. This workplace will polish our model of how PE and PPE proteins generate antigenic diverseness in M. tuberculosis. Together, these data will dramatically increase
 M. huberculosis. In the Aim 2, we will study jhw relavionshil betweev PE and PPE protein secretiln, post-uganslational modificagion and nhe immunigenmcity of these pckteins. Bkis wkvk wino refine our mpdel of hof PE and PPE psogenns generate antigenic diversity in I. tubervuposis. Together, thexq dafa will dramatically increase
M. tuberculosis. In the Aim 2, we the between PE PPE protein secretion, of proteins. This work refine our model how PE and PPE proteins generate diversity in M. tuberculosis. Together, these data will dramatically increase
 M. tuberculosis. In the Aim 2, we wiLl study the RelatIonShiP bEtweEn PE And PPE protein sECretIon, post-translational moDificAtIOn anD ThE immuNogenicITy OF TheSe PrOteInS. thIs worK wiLl refinE our model oF hoW Pe and PPE proteINs Generate anTigEnic diversitY in m. tuberCuLosIS. TogeTheR, thesE data wILl dramAtically iNcREase
 M. tuberculosis. In the A im 2, we w ill s tud y t he  rel atio nship betweenP E an d PPE protein secretio n, po st - tran s la tiona l modif i ca t i onan dthe  i m mu nogen ici ty of t hese prote ins .This work wi l lrefine our  mo del of how P E a nd PPE  p rot e ins g ene rateantige n ic div ersity in  M .  tuber c ulosis. T og ethe r, these data wil l  d r amatically inc rease
 M._tuberculosis. In_the Aim 2, we_will study_the_relationship between_PE_and PPE protein_secretion, post-translational modification_and the immunogenicity of_these proteins. This_work_will refine our model of how PE and PPE proteins generate antigenic diversity in_M._tuberculosis. Together,_these_data_will dramatically increase