premise: Aaron Burr engaged a Secretary of Treasury in a duel.
hypothesis: Aaron Burr . In 1804 , the last full year of his single term as vice president , Burr killed his political rival Alexander Hamilton in a famous duel . The Burr -- Hamilton duel was fought between prominent American politicians Aaron Burr , the sitting Vice President of the United States , and Alexander Hamilton , the former Secretary of the Treasury , at Weehawken , New Jersey on July 11 , 1804 .