premise: John Frusciante is an American musician.
hypothesis: John Anthony Frusciante ( [ fruːˈʃɑːnteɪ ] born March 5 , 1970 ) is an American guitarist , singer , producer and composer . He is best known as the former guitarist of the rock band Red Hot Chili Peppers , from 1988 until 1992 , and again from 1998 until 2009 .