premise: San Francisco Bay Area is located west of the U.S.
hypothesis: Oakland [ ˈoʊklənd ] is the largest city and the county seat of Alameda County , California , United States . A major West Coast port city , Oakland is the largest city in the East Bay region of the San Francisco Bay Area , the third largest city overall in the San Francisco Bay Area , the eighth largest city in California , and the 45th largest city in the United States , with a population of 419,267 .