_:nc52e785faeb74740ba6e93c49ddf5cf9xb31
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"<p>Acetoacetic ester synthesis is a powerful method for the preparation of ketones. It begins with the alkylation\nof acetoacetic ester, an ester derived from a β-keto acid, to form a substituted acetoacetic ester. This substituted\nester can then undergo hydrolysis and decarboxylation, effectively removing the two carbon atoms between the carbonyl\ngroup of the acetoacetate and the newly introduced alkyl group. The end product is a ketone with a carbon skeleton\nthat has been extended by the length of the alkyl halide used in the alkylation step. This synthesis is particularly\nuseful for creating ketones with complex substituents that may be difficult to introduce by other methods.</p>"
<https://chemistry.coach/organic-chemistry-3/enols-enolates-and-aldol-condensation>