_:nc52e785faeb74740ba6e93c49ddf5cf9xb29
<http://schema.org/text>
"<p>The malonic ester synthesis is a method for preparing carboxylic acids with a substituent on the alpha carbon. It involves the alkylation of malonic ester followed by decarboxylation. This method is particularly useful because it allows the introduction of a wide range of substituents in a controlled fashion, enabling the synthesis of substituted acetic acids that are otherwise difficult to obtain directly through other methods.</p>"
<https://chemistry.coach/organic-chemistry-3/enols-enolates-and-aldol-condensation>