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<http://schema.org/text>
"Ilse, as you can see you'll get different answers to this question because it depends on how you create the segmented data.And you also have to be very precise about the terms \"segment\" and \"segmentation.\" When you say \"... a segment based on Account Executives...\" I believe you actually mean a segmentation based on AEs, and a segmentation based on CSMs. (If not, you need to clarify.)When you use what I like to call Dynamic Content™ -- the name Marketo gives to basic segmentation/segment usage in the docs -- you can only divide a single block of content using a single segmentation (all the segments in that segmentation can be used, but not another segmentation).Different content blocks in the same email can use different segmentations, though.So if your signature occupies a single content block (as it usually would), whether you use a segmented Snippet or directly segment the content at the email level (by right-clicking on the element and choosing Segment By) you will only be choosing from the AE segments or the CSM segments.But that's not the only way to do lower-case dynamic content in Marketo. The other way is to use a Velocity script. Unlike Dynamic Content™, dynamic content with Velocity allows you to consult multiple segmentations and segments simultaneously to determine the final content for a block.Also, to get back to Dynamic Content™, you could have two segmented snippets right next to each other, with the Default segment's content blank for each. Then if someone is in the default segment for AE, the final email would have only their CSM segment, and vice versa."
<https://nation.marketo.com/t5/product-discussions/can-i-use-two-different-segments-in-the-same-email/m-p/59750/highlight/true>