<https://www.fpm.org.uk/blog/hydroxychloroquine-history-and-its-cardiovascular-safety/#primaryimage>
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"Figure 3: Simplified schema of the potential mechanism of action of quinine, in particular hydroxychloroquine. Panel (A) (the Pink box to the left) quinines interfere with some membrane receptors, like Toll-like receptor (TLR) or ACE2, preventing binding to their ligands, and by inhibiting the intracellular nucleic acid sensor cyclic GMP-AMP synthesis (cGAS). These will alter the signalling and transcriptional pathway that produces proinflammatory cytokines, interleukins, or interferons. Panel (B) (the yellow box to the right) quinine s decrease the acidic environment of the Lysosome, hindering the functionality of lysosomes as a waste disposal organelle. Thus, preventing their mechanism of endocytosis (which is essential in viral infection) or autophagy, reducing the presentation of the antigens to the immune cells."
<https://www.fpm.org.uk/blog/hydroxychloroquine-history-and-its-cardiovascular-safety/>