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" What is it used for?  Medication given before an operation to sedate the patient  How does it work? This medicine contains two ingredients, papaveretum and hyoscine hydrobromide. Papaveretum is a mixture of three opioids, morphine hydrochloride, codeine hydrochloride and papaverine hydrochloride. They are powerful analgesic (pain-relieving) medicines. They act directly on the brain and spinal cord to alter the perception of pain. They act like the endorphins (naturally occurring hormones)which are produced in the brain and spinal cord and which stop transmission of pain sensation. Nausea and vomiting are common side effects of papaveretum. Hyoscine is an anti-cholinergic medicine used to control nausea and to dry up secretions before surgical operations. It also acts as a mild sedative.This injection is used as pre-operative medication. Warning!  This medicine may cause drowsiness. If affected do not drive or operate machinery. Alcohol should be avoided. The effectiveness of this medicine may decrease if used for long periods of time (tolerance). Administration of this medicine during labour may cause breathing difficulties (respiratory depression) in the new-born baby.  Use with caution in  Breathing problems Elderly people  Not to be used in  Alcoholism Obstructive airways disease People who have taken monoamine-oxidase inhibitor antidepressants (MAOIs) in the last 14 days. Slow, shallow breathing (respiratory depression) Unresponsive unconscious states (comatose states)  This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately. Pregnancy and Breastfeeding Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.  This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than any possible risk to the foetus. Seek medical advice from your doctor. This medicine should be used with caution by breastfeeding mothers, and only if the expected benefit to the mother is greater than any possible risk to the baby. Seek medical advice from your doctor.  Side effects Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.  Difficulty in passing urine (urinary retention) Slow, shallow breathing (respiratory depression) Nausea Addiction to the medicine (dependence) Dizziness Constipation Drowsiness  The side effects listed above may not include all of the side effects reported by the drug&amp;#039;s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist. How can this medicine affect other medicines? Medicines that have a sedative effect on the brain, for example alcohol, sleeping medicines, antihistamines, and antidepressant medicines are likely to increase the effects of papaveretum. Papaveretum should not be taken with MAOI anti-depressants or if MAOIs have been stopped for less than two weeks.When taken together with phenothiazines there may be a severe fall in blood pressure. Last updated 08.07.2004 "^^<http://www.w3.org/2001/XMLSchema#string>
<http://www.netdoctor.co.uk/medicines/aches-and-pains/a7313/papaveretum-and-hyoscine-injection/>