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"Symptoms of jet lag\u2014fatigue, headaches, indigestion, insomnia\u2014occur because the body's internal clock doesn't match the current time at one's destination. People who have entered another time zone can only shift their body clocks to the new schedule by about an hour per day, scientists say. But recent research could lead to new treatments. The genes that help the body's cells tell the time are activated by signals of light and darkness\u2014and now researchers have discovered a gene, SIK1, that slows the process of resetting the biological clock. Blocking this gene's activity made mice more responsive to light conditions and shortened their adjustment to a six-hour time shift (from five days to about two days), says Stuart Peirson, a senior researcher in neuroscience at the University of Oxford in England. Developing this kind of drug for use in people could take years. For now, exposure to natural light at your travel location is the best way to minimize jet lag, and staying well hydrated also helps reduce symptoms, Peirson says.\\n\\n#### See Also\\n\\n- [Preventing Holiday-Travel Meltdowns (at Least for Your Skin)](http://www.allure.com/beauty-trends/blogs/daily-beauty-reporter/2013/12/prevent-holiday-skin-problems.html)\\n\\n\\n- [Insiders' Guide: How to Adjust Your Skin Care When You Travel](http://www.allure.com/beauty-trends/how-to/2013/how-to-adjust-your-skin-care-when-you-travel)\\n\\n\\n- [Insiders' Guide: How to Stock a Travel Beauty Bag](http://www.allure.com/beauty-trends/how-to/2012/how-to-stock-travel-beauty-bag)"^^<http://www.w3.org/2001/XMLSchema#string>
<http://www.allure.com/story/jet-lag-gene>