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"&amp;lt;p&amp;gt;Corticobasal degeneration (CBD), also known as corticobasal ganglionic degeneration, is a rare, progressive neurological disorder. In CBD, brain cells &amp;lt;a href=&amp;quot;https://www.verywell.com/what-is-cerebral-brain-atrophy-98812&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;1&amp;quot;&amp;gt;atrophy&amp;lt;/a&amp;gt; (shrink) and die, and &amp;lt;a href=&amp;quot;https://www.verywell.com/neurofibrillary-tangles-and-alzheimers-disease-98580&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;2&amp;quot;&amp;gt;tau protein&amp;lt;/a&amp;gt; deposits build up in the brain and interfere with functioning. CBD is considered to be a type of &amp;lt;a href=&amp;quot;https://www.verywell.com/what-is-frontotemporal-dementia-98747&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;3&amp;quot;&amp;gt;frontotemporal dementia&amp;lt;/a&amp;gt;.&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Symptoms of CBD&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;CBD shares several symptoms with &amp;lt;a href=&amp;quot;https://www.verywell.com/parkinsons-4014674&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;4&amp;quot;&amp;gt;Parkinson\u2019s disease&amp;lt;/a&amp;gt;. Early symptoms include slow or clumsy movements, tremors or shakiness, muscle weakness, and stiffness. Often, the person with CBD initially has symptoms only on one side of the body. Later, as the disease progresses, both sides are affected.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Some people with CBD experience what is commonly called an &amp;amp;#34;alien limb.&amp;amp;#34; This term refers to an arm or leg that seems to move without any direction of the person. It may not even feel like the arm or leg is a part of the person&amp;amp;#39;s body.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;CBD also affects the ability to speak and understand what others are saying, and can affect &amp;lt;a href=&amp;quot;https://www.verywell.com/types-of-memory-explained-98552&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;5&amp;quot;&amp;gt;memory&amp;lt;/a&amp;gt; and the ability to do mathematical calculations. &amp;lt;a href=&amp;quot;https://www.verywell.com/alzheimers-disease-and-word-finding-difficulties-98554&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;6&amp;quot;&amp;gt;Finding the right word&amp;lt;/a&amp;gt; may become very difficult. &amp;lt;a href=&amp;quot;https://www.verywell.com/personality-changes-in-alzheimers-97989&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;7&amp;quot;&amp;gt;Changes in personality&amp;lt;/a&amp;gt; may develop and can include &amp;lt;a href=&amp;quot;https://www.verywell.com/coping-with-obsessive-compulsive-behavior-97616&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;8&amp;quot;&amp;gt;compulsions,&amp;lt;/a&amp;gt; socially &amp;lt;a href=&amp;quot;https://www.verywell.com/the-complete-guide-to-challenging-behaviors-in-dementia-97607&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;9&amp;quot;&amp;gt;inappropriate behaviors&amp;lt;/a&amp;gt;, and &amp;lt;a href=&amp;quot;https://www.verywell.com/is-repetition-in-dementia-driving-you-crazy-97637&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;10&amp;quot;&amp;gt;repetitive actions.&amp;lt;/a&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Who Gets CBD?&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;Researchers have not yet determined what causes CBD, although it does not appear to be an inherited disorder. The average age of onset is around 60. There are an estimated 2,000 to 3,000 Americans with this disorder, although it&amp;amp;#39;s possible that there are others who have an inaccurate diagnosis, since CBD is often initially misdiagnosed as Parkinson&amp;amp;#39;s or &amp;lt;a href=&amp;quot;https://www.verywell.com/what-is-alzheimers-disease-98795&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;11&amp;quot;&amp;gt;Alzheimer&amp;amp;#39;s disease&amp;lt;/a&amp;gt;.&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Treatment of CBD&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;As with the other disorders in the frontotemporal dementia group, treatment of CBD is limited. Medications that may help relieve some of the symptoms for a limited time include cognitive enhancers (drugs used to attempt to improve the ability to think and remember) that are usually prescribed in Alzheimer\u2019s disease, such as &amp;lt;a href=&amp;quot;https://www.verywell.com/treatment-of-alzheimers-disease-98679&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;12&amp;quot;&amp;gt;cholinesterase inhibitors&amp;lt;/a&amp;gt;.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Other people show some improvement in their physical abilities with medications like Sinemet, a drug often used in Parkinson&amp;amp;#39;s, Baclofen (which helps reduce muscle rigidity or tightness), or Clonazepam, which may help decrease the muscle jerks.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Physical, occupational, and speech therapy may also be ordered by the physician to try to improve the motor functioning and speech, as well as prevent muscle contractures.&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Prognosis&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;CBD is a progressive disease that often causes immobility after about five years; within 10 years, the person may pass away from complications such as a &amp;lt;a href=&amp;quot;https://www.verywell.com/what-is-a-pulmonary-embolism-2249174&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;13&amp;quot;&amp;gt;pulmonary embolism&amp;lt;/a&amp;gt;, &amp;lt;a href=&amp;quot;https://www.verywell.com/all-about-pneumonia-770689&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;14&amp;quot;&amp;gt;pneumonia&amp;lt;/a&amp;gt;, or another &amp;lt;a href=&amp;quot;https://www.verywell.com/how-do-infections-affect-people-with-dementia-98860&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;15&amp;quot;&amp;gt;infection.&amp;lt;/a&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;lt;sub&amp;gt;Sources:&amp;lt;/sub&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;lt;sub&amp;gt;The Association for Frontotemporal Degeneration. Corticobasal Degeneration. Accessed January 27, 2012. &amp;lt;a href=&amp;quot;http://www.theaftd.org/&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;externalLink&amp;quot; data-ordinal=&amp;quot;16&amp;quot;&amp;gt;http://www.theaftd.org/&amp;lt;/a&amp;gt;&amp;lt;/sub&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;lt;sub&amp;gt;National Center for Biotechnology Information. U.S. National Library of Medicine. Pub Med Health. Pick\u2019s Disease.\u00A0&amp;lt;/sub&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;lt;sub&amp;gt;National Institute of Neurological Disorders and Stroke. National Institutes of Health. Corticobasal Degeneration Information Page. Accessed December 11, 2011. &amp;lt;a href=&amp;quot;http://www.ninds.nih.gov/disorders/corticobasal_degeneration/corticobasal_degeneration.htm&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;externalLink&amp;quot; data-ordinal=&amp;quot;17&amp;quot;&amp;gt; http://www.ninds.nih.gov/disorders/corticobasal_degeneration/corticobasal_degeneration.htm&amp;lt;/a&amp;gt;&amp;lt;/sub&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;lt;sub&amp;gt;University of California, San Francisco. Forms of Frontotemporal Dementia. Accessed December 11, 2011. &amp;lt;a href=&amp;quot;http://memory.ucsf.edu/ftd/overview/ftd/forms/multiple&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;externalLink&amp;quot; data-ordinal=&amp;quot;18&amp;quot;&amp;gt; http://memory.ucsf.edu/ftd/overview/ftd/forms/multiple&amp;lt;/a&amp;gt;&amp;lt;/sub&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;lt;sub&amp;gt;University of California, San Francisco. Corticobasal Degeneration Signs and Symptoms. Accessed January 10, 2016. &amp;lt;a href=&amp;quot;http://www.ucsfhealth.org/conditions/corticobasal_degeneration/signs_and_symptoms.html&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;externalLink&amp;quot; data-ordinal=&amp;quot;19&amp;quot;&amp;gt;http://www.ucsfhealth.org/conditions/corticobasal_degeneration/signs_and_symptoms.html&amp;lt;/a&amp;gt;&amp;lt;/sub&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;lt;sub&amp;gt;University of California San Francisco. Corticobasal Degeneration Treatment. Accessed December 16, 2011. &amp;lt;a href=&amp;quot;http://www.ucsfhealth.org/conditions/corticobasal_degeneration/treatment.html&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;externalLink&amp;quot; data-ordinal=&amp;quot;20&amp;quot;&amp;gt;http://www.ucsfhealth.org/conditions/corticobasal_degeneration/treatment.html&amp;lt;/a&amp;gt; &amp;lt;/sub&amp;gt;&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;lt;sub&amp;gt;U.S. Department of Health &amp;amp;amp; Human Services. National Institute on Aging.\u00A0 Frontotemporal Disorders: Information for Patients, Families, and Caregivers&amp;lt;sub&amp;gt;. June 2014. &amp;lt;a href=&amp;quot;https://d2cauhfh6h4x0p.cloudfront.net/s3fs-public/ftd_2014_update-final-lowres.pdf&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;externalLink&amp;quot; data-ordinal=&amp;quot;21&amp;quot; rel=&amp;quot;nofollow&amp;quot;&amp;gt;https://d2cauhfh6h4x0p.cloudfront.net/s3fs-public/ftd_2014_update-final-lowres.pdf&amp;lt;/a&amp;gt;&amp;lt;/sub&amp;gt;&amp;lt;/sub&amp;gt;&amp;lt;/p&amp;gt;"^^<http://www.w3.org/2001/XMLSchema#string>
<https://www.verywell.com/corticobasal-degeneration-98733>