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"&amp;lt;p&amp;gt;Mephedrone is a recent designer drug, commonly referred to as &amp;lt;a href=&amp;quot;https://www.verywell.com/what-are-bath-salts-22084&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;1&amp;quot;&amp;gt;bath salts.&amp;lt;/a&amp;gt;\u00A0Like MDMA, it shares similarities with stimulants and with hallucinogens. Although it has been popularized as a safer alternative, there are medical risks associated with this drug.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Although new on the drug scene, there has been some limited research documenting the effects of mephadrone. This is what users say it feels like to get high on mephadrone.&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Dosage and Duration of Intoxication&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;A study of 100 mephedrone users indicated that an average dose, of 97mg, with 500mg typically being consumed over the course of a drug using session. The typical first session lasted for 6 hours, and other drugs were used in conjunction with mephadrone.\u00A0On this\u00A0first occasion of use,\u00A0participants reported drinking alcohol, using\u00A0&amp;lt;a href=&amp;quot;https://www.verywell.com/what-does-cocaine-high-feel-like-21988&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;2&amp;quot;&amp;gt;cocaine&amp;lt;/a&amp;gt;,\u00A0taking\u00A0&amp;lt;a href=&amp;quot;https://www.verywell.com/what-is-ecstasy-22091&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;3&amp;quot;&amp;gt;MDMA&amp;lt;/a&amp;gt;, smoking\u00A0&amp;lt;a href=&amp;quot;https://www.verywell.com/types-of-marijuana-22323&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;4&amp;quot;&amp;gt;cannabis&amp;lt;/a&amp;gt;\u00A0and/or taking\u00A0&amp;lt;a href=&amp;quot;https://www.verywell.com/what-is-a-k-hole-21861&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;5&amp;quot;&amp;gt;ketamine&amp;lt;/a&amp;gt;.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;In subsequent sessions, most took 125mg intranasally by snorting, or orally. Injection is much less common, but has been documented, sometimes with severe negative consequences.\u00A0These later experiences typically lasted 10 hours, during which 1000mg, with 60 minute breaks between dosages. Use of other substances continued to be the norm, and use took place in groups of ten or so.&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Stimulant\u00A0Effects&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;The initial sensations associated with getting high on mephadrone are similar to those of other stimulant drugs, and include\u00A0\u2018self-confidence\u2019, \u2018buzzing\u2019,\u00A0\u2018dizziness\u2019 and \u2018impaired concentration and memory\u2019. \u00A0In another study, mephedrone users described\u00A0pleasant mood, euphoria, ease, suppressed appetite, dry mouth, sharpened\u00A0perception, insomnia and increased energy occurring most of the time when on mephedrone.&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Entactogen Effects&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;Entactogen effects add to the more straightforward feelings of stimulation and being wide-awake and energetic, with feelings of connection to self and others. This is described by users as\u00A0feeling&amp;lt;br/&amp;gt;oneself close to others, enhanced empathy,\u00A0and is most frequently attributed to the drug, ecstasy or MDMA.\u00A0A reduction in feelings of hostility towards others, and an increased sense of personal insight are also reported.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;When these feelings of being comfortable with others, and with oneself, are\u00A0combined with increased feelings of sexual desire and stimulation, enhanced mood, talkativeness, intensification of sensory experience, increased self confidence\u00A0and increased urge to move, it is easy to see how mephedrone\u00A0could\u00A0become a party and play drug. Indeed, as with ecstasy, the use of mephadrone can easily transfer from the nightclub scene to sex parties. Unfortunately, this also increases the risks to users.&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Cravings&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;Even shortly after taking mephedrone users report a strong feeling of\u00A0\u2018wanting\u2019 more of\u00A0the drug. This mephedrone &amp;lt;a href=&amp;quot;https://www.verywell.com/tips-for-coping-with-withdrawal-cravings-22371&amp;quot; data-component=&amp;quot;link&amp;quot; data-source=&amp;quot;inlineLink&amp;quot; data-type=&amp;quot;internalLink&amp;quot; data-ordinal=&amp;quot;6&amp;quot;&amp;gt;craving&amp;lt;/a&amp;gt;\u00A0was\u00A0the most frequently reported acute effect of the drug in\u00A0one study.\u00A0Further, \u2018wanting mephedrone\u2019 was also intensified\u00A0when users were actually sober but were thinking about their next mephadrone.\u00A0&amp;lt;/p&amp;gt;&amp;lt;h3&amp;gt;Withdrawal Related Effects&amp;lt;/h3&amp;gt;&amp;lt;p&amp;gt;Tiredness, insomnia, nasal congestion\u00A0and impaired concentration were the most\u00A0prevalent\u00A0withdrawal-related effects (with nasal congestion the\u00A0most intense effect).&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Sources&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Freeman, Tom P.; Morgan, Celia J. A.; Vaughn-Jones, James; Hussain, Nahida; Karimi, Kash; Curran, H. Valerie; Cognitive and subjective effects of mephedrone and factors influencing use of a &amp;amp;#39;new legal high&amp;amp;#39;.\u00A0Addiction, 107 (4): 792-800.\u00A02012.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Kapit\u00E1ny-F\u00F6v\u00E9ny M; Kert\u00E9sz M; Winstock A; Deluca P; Corazza O; Farkas J; Zacher G; Urb\u00E1n R; Demetrovics Z,\u00A0Substitutional potential of mephedrone: an analysis of the\u00A0subjective effects.\u00A0Hum. Psychopharmacol Clin Exp\u00A028: 308\u2013316.\u00A02013.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Measham, Fiona; Wood, David M.; Dargan, Paul I.; Moore, Karenza. The rise in legal highs: prevalence and patterns in the use of illegal drugs and first- and second-generation &amp;amp;#39;&amp;amp;#39;legal highs&amp;amp;#39;&amp;amp;#39; in South London gay dance clubs.\u00A0&amp;lt;em&amp;gt;Journal of Substance Use\u00A0&amp;lt;/em&amp;gt;16 (4): 263-72. 2011.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Winstock, Adam;\u00A0Mitcheson, Luke;\u00A0Ramsey, John;\u00A0Davies, Susannah;\u00A0Puchnarewicz, Malgorzata;\u00A0Marsden, John\u00A0Mephedrone: use, subjective effects and health risks\u00A0Addiction\u00A0106 (11): 1991-6.\u00A02011.&amp;lt;/p&amp;gt;"^^<http://www.w3.org/2001/XMLSchema#string>
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