thumb|right|Comparing Serial Numbers 1 and 1000 of Spinco's Model E Analytical Ultracentrifuge, 1965 In 1946, Pickels cofounded Spinco (Specialized Instruments Corp.) to market analytical and preparative ultracentrifuges based on his design. Pickels considered his design to be too complicated for commercial use and developed a more easily operated, “foolproof” version. But even with the enhanced design, sales of analytical centrifuges remained low, and Spinco almost went bankrupt. The company survived by concentrating on sales of preparative ultracentrifuge models, which were becoming popular as workhorses in biomedical laboratories. In 1949, Spinco introduced the Model L, the first preparative ultracentrifuge to reach a maximum speed of 40,000 rpm. In 1954, Beckman Instruments (later Beckman Coulter) purchased the company, forming the basis of its Spinco centrifuge division.Arnold O. Beckman: One Hundred Years of Excellence. By Arnold Thackray and Minor Myers, Jr. Philadelphia: Chemical Heritage Foundation, 2000.
tHumb|rigHT|COmPaRing seriAl NumberS 1 And 1000 oF spincO's MOdel e anAlYTIcal uLtracEntrifugE, 1965 In 1946, PiCkEls cOfouNded spInCO (SpecIAlIzed InsTrumeNTS CorP.) TO market anaLYtIcaL aNd prepaRAtivE ulTracentRiFUgeS baSed ON hIS dEsign. pICkels conSIdered HIs desIgn to be tOo ComPlicated FoR CommerciaL uSe and deVeLOPed a mOre Easily oPerATEd, “FooLPRoOf” VersioN. buT even wITh tHE enHANcEd DeSign, sALEs of analyTical cEntrifuGes remaIned loW, AND spInco aLmost weNt bANkrUPt. ThE ComPanY survivEd bY concENtrating oN sales of prepARative uLtRacentrifuGE mOdeLs, wHich werE BEComING popUlaR As worKHOrses in BIOmeDical laBorAtories. in 1949, spiNCO iNTRoducEd tHE modeL l, The fIrSt preparaTive ulTraCentRifuGe to REaCh a MAximuM speed of 40,000 rpm. in 1954, BeCKmaN iNSTrUmEnts (later bECkMAN coUlter) purchaSed thE comPAny, foRminG tHe Basis oF iTs sPIncO CEnTrIfuge dIVision.aRNolD o. BecKMAn: ONe HUNdred years of eXCElLenCE. bY ArnOld thackray aNd minOR myerS, JR. PhiLAdelphIA: chEmicaL HeritagE FoUNdaTiOn, 2000.