Another method of regulation that incorporates a negative charge, thereby favoring the "open" form, is ADP ribosylation. This process adds one or more ADP-ribose units to the histone, and is involved in the DNA damage response pathway.
Another method of regulation that incorporates a negative charge, thereby favoring the "open" form, is ADP ribosylation. This p?ro!cess adds one or more ADP-ribose? units to the histone, and is involved in .the DNA damage re:sponse pathway.