Pfeiffer's next role was that of high school teacher and former United States Marine LouAnne Johnson in the drama Dangerous Minds (1995), co-produced by her company. She appeared as her character in the music video for the soundtrack's lead single, "Gangsta's Paradise" by Coolio, featuring L.V.; the song won the 1996 Grammy Award for Best Rap Solo Performance, and the video won the MTV Video Music Award for Best Rap Video. While Dangerous Minds received negative reviews, it was a box office success, grossing US$179.5 million around the globe. In 1996, Pfeiffer portrayed Sally Atwater in the romantic drama Up Close & Personal, with Robert Redford, took on the titular role in the drama To Gillian on Her 37th Birthday, which was adapted by her husband David Kelley from Michael Brady's play of the same name, and served as an executive producer and starred as the divorced single mother architect Melanie Parker in the romantic comedy One Fine Day, with George Clooney.
Pfeiffer's next role was that of high school teacher and former United States Marine LouAnne Johnson in the drama Dangerous Minds (1995) co-produced by her company She appeared as her character in the music video for the soundtrack's lead single "Gangsta's Paradise" by Coolio featuring LV; the song won the 1996 Grammy Award for Best Rap Solo Performance and the video won the MTV Video Music Award for Best Rap Video While Dangerous Minds received negative reviews it was a box office success grossing US$1795 million around the globe In 1996 Pfeiffer portrayed Sally Atwater in the romantic drama Up Close & Personal with Robert Redford took on the titular role in the drama To Gillian on Her 37th Birthday which was adapted by her husband David Kelley from Michael Brady's play of the same name and served as an executive producer and starred as the divorced single mother architect Melanie Parker in the romantic comedy One Fine Day with George Clooney