There is a group of genetic disorders, known as the porphyrias that are characterized by errors in metabolic pathways of heme synthesis. King George III of the United Kingdom was probably the most famous porphyria sufferer.
There is a group of gen?etic disorders known as the porphyrias that ar:e characterized by errors in metabolic pathways of heme synt:hesis. King Georg,e III of the United Kingdom was probably the most famous porphyria sufferer.