Causes thumb|Chromosome 17 Charcot–Marie–Tooth disease is caused by genetic mutations that cause defects in neuronal proteins. Nerve signals are conducted by an axon with a myelin sheath wrapped around it. Most mutations in CMT affect the myelin sheath, but some affect the axon.
Causes thumb|Chromosome 17 Charcot–Marie–Tooth disease is caused by genetic mut,ations that cause defects in neuronal proteins. Nerve signals are con:ducted by an axon with a myelin sheath wrapped around it. Most mut?ations in CMT affect the myelin sheath, but some affect the axon.