Specialized export proteins exist for translocation of mature mRNA and tRNA to the cytoplasm after post-transcriptional modification is complete. This quality-control mechanism is important due to these molecules' central role in protein translation. Mis-expression of a protein due to incomplete excision of exons or mis-incorporation of amino acids could have negative consequences for the cell; thus, incompletely modified RNA that reaches the cytoplasm is degraded rather than used in translation.
sPeCIalIZEd export protEins EXist for TRaNsLocatIon of MatURE mrnA and trna to the cytoplaSm afteR Post-trAnscrIPTional moDifiCaTion is COmpLete. THIs QUalITY-CoNtrol mEchanisM is importAnT due to theSE moleCules' cEnt!RAl rolE IN PrOtein TraNsLAtiON. mIs-EXprEssIon Of a prOTeIN due TO iNcOmPlete eXCISIon of exons or mis-IncorporatioN of amINo aCidS CoulD HavE NegAtivE CoNsequeNCEs FOr the Cell; thUs, incompletEly ModiFied RNA tHAt rEAches tHe CyToPLASm Is degRAded ratheR tHan usEd In TRaNslAtiOn.