History The area which is now Yazoo County was acquired by the State of Mississippi from the Choctaw Indians in 1820. Yazoo County was established on January 21, 1823. It was the 19th county established in the State of Mississippi, and remains the largest in area. It was developed for cotton plantations, which lined the major river to have transportation access.
history the area which is now yazoo county was acquired by the state of mississippi from the choctaw indians in 1820 yazoo county was established on january 21 1823 it was the 19th county established in the state of mississippi and remains the largest in area it was developed for cotton plantations which lined the major river to have transportation access