Therapeutic effects Pain relief: Primarily, fentanyl provides the relief of pain by acting on the brain and spinal μ-receptors. Sedation: Fentanyl produces sleep and drowsiness, as the dosage is increased, and can produce the δ-waves often seen in natural sleep on electroencephalogram. Suppression of the cough reflex: Fentanyl can decrease the struggle against an endotracheal tube and excessive coughing by decreasing the cough reflex, becoming useful when intubating people who are awake and have compromised airways. After receiving a bolus dose of fentanyl, people can also experience paradoxical coughing, which is a phenomenon that is not well understood.
Therapeutic effects Pain relief Primarily fentanyl provides the relief of pain by acting on the brain and spinal μ-receptors Sedation Fentanyl produces sleep and drowsiness as the dosage is increased and can produce the δ-waves often seen in natural sleep on electroencephalogram Suppression of the cough reflex Fentanyl can decrease the struggle against an endotracheal tube and excessive coughing by decreasing the cough reflex becoming useful when intubating people who are awake and have compromised airways After receiving a bolus dose of fentanyl people can also experience paradoxical coughing which is a phenomenon that is not well understood