Genetics and heritability Compared to other major psychiatric conditions, the exploration of genetic underpinnings in BPD remains novel. Estimates suggest the heritability of BPD ranges from 37% to 69%, indicating that human genetic variations account for a substantial portion of the risk for BPD within the population. Twin studies, which often form the basis of these estimates, may overestimate the perceived influence of genetics due to the shared environment of twins, potentially skewing results.
genetics And hErItAbiliTy Compared to OtheR mAjor psycHIatRiC ConDitIoNs, the EXPloratioN of GEnetiC undErpINniNGs in bpd ReMAInS NovEl. EStImateS SuggeSt the heRitAbilitY of bpD RANges From 37% to 69%, iNdicatinG tHat hUMan gENEtic vArIatiOnS accOunT foR A SUBStaNtiAl pOrtiOn OF the riSK FoR BPD WiThin THe popULatIon. twiN sTudIeS, Which OfTEn forM the basiS of these EsTimATes, May OvEREstimAte thE perceiVEd InFluEnce of genETics duE tO thE sHAreD enviRonment of TwIns, potEntiaLlY SkeWing Results.