Vermigli's best-known theological contribution was defending the Reformed doctrine of the Eucharist against Catholics and Lutherans. Contrary to the Catholic doctrine of transubstantiation, Vermigli did not believe that the bread and wine are changed into Christ's body and blood. He also disagreed with the Lutheran view that Christ's body is ubiquitous and so can be physically present at the Eucharist. Instead, Vermigli taught that Christ remains in Heaven even though he is offered to those who partake of the Eucharist and received by believers.
Vermigli's best-known theological contribution was defending the Reformed doctrine of the Eucharist against Catholics and Lutherans. Contrary to the Catholic doctrine of transubstantiation, Vermigli di,d not be.lieve that the bread and wine are changed into Christ's body and blood. He also disagreed with the Lutheran view that Christ's body is ubiquitous and so can be physically present at the Eucharist Instead Vermigli taught that Christ remains in Heaven even though he is offered to those who partake of the Eucharis.t and received by believers