Topiramate is an antiepileptic medication which had been studied to assess the efficacy and safety in the treatment of ET. Overall, it is considered a second-line therapy alone or in combination with other medications when first-line treatments fail to show improvement or medication intolerance. Topiramate has been shown effective in reducing limb tremors at the maximum dose of 200 mg, however, there was a higher risk for the development of adverse effects including weight loss, anorexia, cognitive impairment, and kidney stones.
Topiramate is an antiepileptic medication which had been studied to assess the efficacy and safety in the treatment of ET. Overall, it is considered a second-line therapy alone or in combination with other medications when first-line treatments fail to show improvement or medication intolerance. Topiramate has been shown effective in reducing limb tremors at the maximum dose of 200 mg, however, there was a higher risk for the development of adverse effects including weight loss, anorexia, cognitive impairment and kidney stones.