Degradation resistance in nature Overwhelming evidence shows that prions resist degradation and persist in the environment for years, and proteases do not degrade them. Experimental evidence shows that unbound prions degrade over time, while soil-bound prions remain at stable or increasing levels, suggesting that prions likely accumulate in the environment. One 2015 study by US scientists found that repeated drying and wetting may render soil bound prions less infectious, although this was dependent on the soil type they were bound to.
Degradation resistance in nature Overwhelming evidence shows that prions resist degradation and persist in the environment for years and proteases do not degrade them Experimental evidence shows that unbound prions degrade over time while soil-bound prions remain at stable or increasing levels suggesting that prions likely accumulate in the environment One 2015 study by US scientists found that repeated drying and wetting may render soil bound prions less infectious although this was dependent on the soil type they were bound to