Ladue began as a farming community St. Louis County suburb. After St. Louis City ejected St. Louis County in 1876, Ladue was known as ranges 4 and 5 of "Township 45", with Clayton being the political hub. Original Township 45 farming families included the Dennys, Dwyers, Conways, McCutcheons, McKnights (all Irish), Litzsinger, von Schraders, Spoedes, Luedloffs, Muellers, Seigers (all German), LaDues (French), Warsons, Lays, Barnes, Prices, and Watsons (all English), according to a 1868 Pitzman map of St. Louis,1868 Pitzman map of St. Louis County as well as 1878 and 1909 maps of St. Louis County.
Ladue began as a farming community St. Louis County suburb. After St. Louis City ejected St. Louis County in 1876, Ladue was known as ranges 4 and 5 of "Township 45", with Clayton being the political hub. Original Township 45 farming families included the Dennys, Dwyers, Conways, McCutcheons, McKnights (all Irish), Litzsinger, von Schraders, Spoedes, Luedloffs, Muellers, Seigers (all German), LaDues (French), Warsons, Lays, Barnes, Prices, and Watsons (all English), according to a 1868 Pitzman map of St. Louis,1868 Pitzman map of St. Louis County as well as 1878 and 1909 maps of St. Louis County.