New York State Route 53 is a north–south highway through the town. left|thumb|The former Kanona & Prattsburgh station in Wheeler From c. 1889–1961, Wheeler was located on a railroad. The Kanona & Prattsburgh Railroad Company, the Kanona & Prattsburgh Railway Company, and the Prattsburgh Railway Corporation during the period operated an 11.44 single-track standard-gauge railroad from a connection with the Erie Railroad at Kanona to Prattsburgh. Intermediate stations included Wheeler, Beans, and Stickneys, though Wheeler was the only one with a full-time agent (until c.1930).
New York State Route 53 is a north–south highway through the town left|thumb|The former Kanona & Prattsburgh station in Wheeler From c 1889–1961 Wheeler was located on a railroad The Kanona & Prattsburgh Railroad Company the Kanona & Prattsburgh Railway Company and the Prattsburgh Railway Corporation during the period operated an 1144 single-track standard-gauge railroad from a connection with the Erie Railroad at Kanona to Prattsburgh Intermediate stations included Wheeler Beans and Stickneys though Wheeler was the only one with a full-time agent (until c1930)