Riboflavin kinase Riboflavin kinase catalyzes the phosphorylation of riboflavin to create flavin mononucleotide(FMN). It has an ordered binding mechanism where riboflavin must bind to the kinase before it binds to the ATP molecule. Divalent cations help coordinate the nucleotide. The general mechanism is shown in the figure below.thumb|upright=2.5|center|Mechanism of riboflavin kinase. Riboflavin kinase plays an important role in cells, as FMN is an important cofactor. FMN also is a precursor to flavin adenine dinucleotide(FAD), a redox cofactor used by many enzymes, including many in metabolism. In fact, there are some enzymes that are capable of carrying out both the phosphorylation of riboflavin to FMN, as well as the FMN to FAD reaction. Riboflavin kinase may help prevent stroke, and could possibly be used as a treatment in the future. It is also implicated in infection, when studied in mice.
Riboflavin kinase Riboflavin kinase catalyzes the phosphorylation of riboflavin to create flavin mononucleotide(FMN). It has an orde:red binding mechanism where riboflavin must bind to the kinase before it binds to the ATP molecule. Divalent cations help coordinate the nucleotide. The general mechanism is shown in the figure below.thumb|upright=2.5|center|Mechanism of riboflavin kinase. Riboflavin kinase plays an important role in cells, as FMN is an important cofactor. FMN also is a precursor to flavin adenine dinucleotide(FAD), a redox cofactor used by many enzymes, including many in metabolism. In fact there are some en!zymes that are capable of carrying out both the phosphorylation of riboflavin to FMN, as well as the FMN to FAD: re,action. Riboflavin kinase may help prevent stroke, and could possibly be used as a treatment in the future. It is also implicated in infection, when studied in mice.