All known prion diseases in mammals affect the structure of the brain or other neural tissues. These diseases are progressive, have no known effective treatment, and are invariably fatal. Most prion diseases were thought to be caused by PrP until 2015 when a prion form of alpha-synuclein was linked to multiple system atrophy (MSA). Prions are also linked to other neurodegenerative diseases like Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), which are sometimes referred to as prion-like diseases.
All known prion diseases in mammals affect the structure of the brain or other neural tissues. These diseases are progressive, have no known effecti,ve treatment, and are invariably fatal. Most prion diseases were thought to be caused by ,PrP until 2015 when a prion form of alpha-synuclein was linked to multiple system atrophy (MSA). Prions are also linked to other neurodegenerative diseases like Alzheimer's disease Parkinson's disease and amyotrophic lateral sclerosis (ALS), which are sometimes referred to as prion-like diseases.