Matlacha Isles-Matlacha Shores is an unincorporated community and census-designated place (CDP) in Lee County, Florida, United States. The population was 227 at the 2020 census, down from 229 at the 2010 census. It is part of the Cape Coral-Fort Myers, Florida Metropolitan Statistical Area.
Matlacha Isles-Matlacha Shores is an unincorporated community and census-designated place (CDP) in Lee County Florida United States The population was 227 at the 2020 census down from 229 at the 2010 census It is part of the Cape Coral-Fort Myers Florida Metropolitan Statistical Area