The ribosome initially attaches to the mRNA at the start codon (AUG) and begins to translate the molecule. The mRNA nucleotide sequence is read in triplets; three adjacent nucleotides in the mRNA molecule correspond to a single codon. Each tRNA has an exposed sequence of three nucleotides, known as the anticodon, which are complementary in sequence to a specific codon that may be present in mRNA. For example, the first codon encountered is the start codon composed of the nucleotides AUG. The correct tRNA with the anticodon (complementary 3 nucleotide sequence UAC) binds to the mRNA using the ribosome. This tRNA delivers the correct amino acid corresponding to the mRNA codon, in the case of the start codon, this is the amino acid methionine. The next codon (adjacent to the start codon) is then bound by the correct tRNA with complementary anticodon, delivering the next amino acid to ribosome. The ribosome then uses its peptidyl transferase enzymatic activity to catalyze the formation of the covalent peptide bond between the two adjacent amino acids.
The ribosome initially attaches to the mRNA at the start codon (AUG) and begins to translate the molecule The mRNA nucleotide sequence is read in triplets; three adjacent nucleotides in the mRNA molecule correspond to a single codon Each tRNA has an exposed sequence of three nucleotides known as the anticodon which are complementary in sequence to a specific codon that may be present in mRNA For example the first codon encountered is the start codon composed of the nucleotides AUG The correct tRNA with the anticodon (complementary 3 nucleotide sequence UAC) binds to the mRNA using the ribosome This tRNA delivers the correct amino acid corresponding to the mRNA codon in the case of the start codon this is the amino acid methionine The next codon (adjacent to the start codon) is then bound by the correct tRNA with complementary anticodon delivering the next amino acid to ribosome The ribosome then uses its peptidyl transferase enzymatic activity to catalyze the formation of the covalent peptide bond between the two adjacent amino acids