thumb|upright=1.35|Habsburg realms (green) under Charles V, Holy Roman Emperor The marriage produced three children, of whom only two survived: Philip I of Castile (1478–1506) who inherited his mother's domains following her death, but predeceased his father. He married Joanna of Castile, becoming king-consort of Castile upon her accession in 1504, and was the father of the Holy Roman Emperors Charles V and Ferdinand I. Margaret of Austria (1480–1530), who was first engaged at the age of two to the French dauphin (who became Charles VIII of France a year later) to confirm peace between France and Burgundy. She was sent back to her father in 1492 after Charles repudiated their betrothal to marry Anne of Brittany. She was then married to John, Prince of Asturias, crown prince of Castile and Aragon, and after his death to Philibert II of Savoy. She undertook the guardianship of her deceased brother Philip's children, and governed Burgundy for the heir, Charles. Francis of Austria, who died shortly after his birth in 1481. Maximilian was also married to Anne of Brittany (1477–1514). They were married by proxy in Rennes on 18 December 1490. The contract was dissolved by Pope Innocent VIII in early 1492, after Charles VIII had repudiated his betrothal to Margaret and forced Anne to marry him instead.
thumb|upright=135|Habsburg realms (green) under Charles V Holy Roman Emperor The marriage produced three children of whom only two survived Philip I of Castile (1478–1506) who inherited his mother's domains following her death but predeceased his father He married Joanna of Castile becoming king-consort of Castile upon her accession in 1504 and was the father of the Holy Roman Emperors Charles V and Ferdinand I Margaret of Austria (1480–1530) who was first engaged at the age of two to the French dauphin (who became Charles VIII of France a year later) to confirm peace between France and Burgundy She was sent back to her father in 1492 after Charles repudiated their betrothal to marry Anne of Brittany She was then married to John Prince of Asturias crown prince of Castile and Aragon and after his death to Philibert II of Savoy She undertook the guardianship of her deceased brother Philip's children and governed Burgundy for the heir Charles Francis of Austria who died shortly after his birth in 1481 Maximilian was also married to Anne of Brittany (1477–1514) They were married by proxy in Rennes on 18 December 1490 The contract was dissolved by Pope Innocent VIII in early 1492 after Charles VIII had repudiated his betrothal to Margaret and forced Anne to marry him instead