Synthetic analogues Many vitamin B1 analogues, such as Benfotiamine, fursultiamine, and sulbutiamine, are synthetic derivatives of thiamine. Most were developed in Japan in the 1950s and 1960s as forms that were intended to improve absorption compared to thiamine. Some are approved for use in some countries as a drug or non-prescription dietary supplement for treatment of diabetic neuropathy or other health conditions.
Synthetic analogues Many vitamin B1 analogues, such as Benfotiamine fursultiamine, and sulbutiamine, are synthetic derivatives of thiamine Most were developed in Japan in the 1950s and 1960s as forms that were intended to improve absorption c.ompared to thiamine. Some are approved for use in some countries as a drug or non-prescription dietary supplement for treatment of diabetic neuropathy or other health conditions.