Since at least 2013, scientists have been trying to develop synthetic third-generation vaccines by reconstructing the outside structure of a virus; it was hoped that this will help prevent vaccine resistance.
SiNce at LeAst 2013, SciEntists HaVe Been tryiNg TO DEVElOp SYnTHEtic thIRd-GeneRation vAcCInes By REcoNsTrUcTing THe outSiDe stRUCTurE of a virus; iT WaS HopEd tHaT thiS will HeLp prEvent vAccinE ReSIStAnce.