Major highways 40px Interstate 75 The county's only fully controlled-access freeway, and has 10 interchanges within Lee County, linking the area to Naples, Fort Lauderdale, and Miami to the south and east; and Sarasota and Tampa to the north. The freeway is at least six lanes throughout Lee County and is up to eight lanes in some areas. 40px U.S. Route 41Tamiami TrailCleveland Avenue US 41 runs the length of Lee County, and is the county's main north–south arterial highway. It is a major commercial corridor, running as an elevated highway through the center of downtown Fort Myers, continuing south as a multilane, divided-surface highway through the communities of South Fort Myers, San Carlos Park, Estero, and Bonita Springs. From north-to-south, the highway's name starts as "North Tamiami Trail", changes to "Cleveland Avenue" from the Caloosahatchee River to State Road 884 (Colonial Boulevard) in the City of Fort Myers; then it is called "South Cleveland Avenue" from Colonial Boulevard to County Road 876 (Daniels Parkway), and then changes to South Tamiami Trail until the border with Collier County. 40px State Road 80Palm Beach Boulevard SR 80's western terminus is in downtown Fort Myers. The multilane highway runs east-northeast along the southern banks of the Caloosahatchee River as "Palm Beach Boulevard" within the county, traversing the state of Florida to connect the area with LaBelle, Clewiston, and West Palm Beach. 40px State Road 82Dr. Martin Luther King Jr. BoulevardImmokalee Road SR 82's western terminus is in downtown Fort Myers. The highway is called "Dr. Martin Luther King Jr. Boulevard" within the incorporated limits of the City of Fort Myers, becoming "Immokalee Road" as it passes through Lehigh Acres and connects the area to Immokalee. 45px State Road 884Veterans Memorial ParkwayColonial BoulevardLee Boulevard SR 884 is Lee County's main east–west arterial highway. Its western terminus is in the incorporated limits of the City of Cape Coral and the eastern terminus is in Lehigh Acres. Within Cape Coral, the highway is named "Veterans' Memorial Parkway", and is a multilane, controlled-access highway. Within Fort Myers, it is named "Colonial Boulevard". The road crosses the Caloosahatchee River as an elevated highway across a toll bridge, interchanging with U.S. Highway 41 and Interstate 75, then becomes a multilane, divided-surface highway through Lehigh Acres. After it intersects with State Road 82, it is called "Lee Boulevard".
Major highways 40px Interstate 75 The county's only fully controlled-access freeway and has 10 interchanges within Lee County linking the area to Naples Fort Lauderdale and Miami to the south and east; and Sarasota and Tampa to the north The freeway is at least six lanes throughout Lee County and is up to eight lanes in some areas 40px US Route 41Tamiami TrailCleveland Avenue US 41 runs the length of Lee County and is the county's main north–south arterial highway It is a major commercial corridor running as an elevated highway through the center of downtown Fort Myers continuing south as a multilane divided-surface highway through the communities of South Fort Myers San Carlos Park Estero and Bonita Springs From north-to-south the highway's name starts as "North Tamiami Trail" changes to "Cleveland Avenue" from the Caloosahatchee River to State Road 884 (Colonial Boulevard) in the City of Fort Myers; then it is called "South Cleveland Avenue" from Colonial Boulevard to County Road 876 (Daniels Parkway) and then changes to South Tamiami Trail until the border with Collier County 40px State Road 80Palm Beach Boulevard SR 80's western terminus is in downtown Fort Myers The multilane highway runs east-northeast along the southern banks of the Caloosahatchee River as "Palm Beach Boulevard" within the county traversing the state of Florida to connect the area with LaBelle Clewiston and West Palm Beach 40px State Road 82Dr Martin Luther King Jr BoulevardImmokalee Road SR 82's western terminus is in downtown Fort Myers The highway is called "Dr Martin Luther King Jr Boulevard" within the incorporated limits of the City of Fort Myers becoming "Immokalee Road" as it passes through Lehigh Acres and connects the area to Immokalee 45px State Road 884Veterans Memorial ParkwayColonial BoulevardLee Boulevard SR 884 is Lee County's main east–west arterial highway Its western terminus is in the incorporated limits of the City of Cape Coral and the eastern terminus is in Lehigh Acres Within Cape Coral the highway is named "Veterans' Memorial Parkway" and is a multilane controlled-access highway Within Fort Myers it is named "Colonial Boulevard" The road crosses the Caloosahatchee River as an elevated highway across a toll bridge interchanging with US Highway 41 and Interstate 75 then becomes a multilane divided-surface highway through Lehigh Acres After it intersects with State Road 82 it is called "Lee Boulevard"