His music has been a staple of the children's television shows Rugrats, Beakman's World, Santo Bugito and Clifford the Big Red Dog. He wrote the new theme song for the original Felix the Cat show when it was sold to Broadway Video, some music for Pee-wee's Playhouse in 1986–1990 and the theme song for the Super Mario World TV series for DIC Entertainment in 1991. The character design for Chuckie on Rugrats was loosely based on him. Along with Bob Casale, he produced Heroes & Villains (2000), a soundtrack album with music inspired by The Powerpuff Girls. Mothersbaugh originally sought out to be the show's main composer, but his demo was rejected by creator Craig McCracken, who despite being a Devo fan, had concerns about his cartoon being pushed aside if a big feature film came to Mothersbaugh's production company.
His music has been a staple of the children's television shows Rugrats, Beakman's World, Santo Bugito and Clifford the Big Red Dog. He wrote the new theme song for the original Felix the Cat show when it was sold to Broadway Video, some music for Pee-wee's Playhouse in 1986–1990 and the theme song for the Super Mario World TV series for DIC Entertainment in 1991. The character design for Chuckie on Rugrats was loosely based on him. Along with Bob Casale, he produced Heroes & Villains (2000), a soundtrack album with music inspired by The Powerpuff Girls. Mothersbaugh originally sought out to be the show's main composer, but his demo was rejected by creator Craig McCracken, who despite being a Devo fan, had concerns about his cartoon being pushed aside if a big feature film came to Mothersbaugh's production company.