Individuals who are exposed to the virus, either through infection or by immunization via polio vaccine, develop immunity. In immune individuals, IgA antibodies against poliovirus are present in the tonsils and gastrointestinal tract and able to block virus replication; IgG and IgM antibodies against PV can prevent the spread of the virus to motor neurons of the central nervous system. Infection or vaccination with one serotype of poliovirus does not provide immunity against the other serotypes, and full immunity requires exposure to each serotype.
individuals who are exposed to the virus either through infection or by immunization via polio vaccine develop immunity in immune individuals iga antibodies against poliovirus are present in the tonsils and gastrointestinal tract and able to block virus replication; igg and igm antibodies against pv can prevent the spread of the virus to motor neurons of the central nervous system infection or vaccination with one serotype of poliovirus does not provide immunity against the other serotypes and full immunity requires exposure to each serotype