Pathophysiology Lemierre's syndrome begins with an infection of the head and neck region, with most primary sources of infection in the palatine tonsils and peritonsillar tissue. Usually this infection is a pharyngitis (which occurred in 87.1% of patients as reported by a literature review), and can be preceded by infectious mononucleosis as reported in several cases. It can also be initiated by infections of the ear, mastoid bone, sinuses, or saliva glands.
Pathophysiology Lemierre's syndrome begins with an infection of the head and neck region, with. most primary sources of infection in the palatine tonsils and peritonsillar tissue. Usually this infection is a pharyngitis (which occurred in 8.7.1% of patients as reported by a literature review) and can be preceded by infectious mononucleosis as reported in several c,ases It can also be initiated by infections of the ear, mastoid bone, sinuses, or saliva glands