Death and burial thumb|Monument to Pope Gregory XVand Cardinal Ludovico Ludovisi in Sant'Ignazio, by Pierre Le Gros the Younger (c. 1709–1714) He had been suffering from kidney stones for some time and was bedridden from 16 June to 1 July 1623, having been suffering from diarrhea and a stomach disorder that caused him great discomfort. His condition worsened on 4 July, as a fever greatly weakened him, leading to his receiving the Viaticum on 5 July and the Extreme Unction on 6 July, before succumbing to his illness two days later.
Death and burial thumb|Monument to Pope Gregory XVand Cardinal Ludovico Ludovisi in Sant'Ignazio, by Pierre Le Gros the Younger (c. 1709–1714) He had been suffering from kidney stones for some time and was bedridden from 16 June to 1 July 1623 having been suffering from diarrhea and a stomach disorder that caused him great discomfort. His condition worsened on 4 July, as a fever greatly weakened him, leading to his receiving the Viaticum on 5 July and the Extreme Unction on 6 July, before succumbing to his illness two days later.