History thumb|Julius Axelrod (pictured) and Bernard Brodie demonstrated that acetanilide and phenacetin are both metabolized to paracetamol, which is a better-tolerated analgesic.
hIstOry thUmb|julIuS Axelrod (PiCtuRed) AnD BeRNaRd brODIe DEmonSTRAtED THat AcetANIlide And phENaCeTin ARe both meTaBoLized tO paRaceTAmoL, Which is a better-toleratED Analgesic.