Their music has spawned "a litter of like-minded bands", including industrial rock project Nine Inch Nails, who opened for Skinny Puppy for a short time on their 1988 VIVIsectVI tour. Trent Reznor also acknowledged that Skinny Puppy's "Dig It" inspired the very first Nine Inch Nails track written, "Down in It". Canadian synth-pop artist Grimes includes Skinny Puppy as an influence on her music, having grown up in Vancouver's industrial music scene. Sara Taylor of the EBM group Youth Code has said that the song "Worlock" was "one of the most influential songs" she had ever heard. Other artists impacted by Skinny Puppy's music include Marilyn Manson, Chester Bennington, Moby, Jonathan Davis, Daron Malakian, 3Teeth, Foals vocalist Yannis Philippakis, Al Jourgensen, Chris Vrenna, John Grant, Mortiis, Blush Response, Celldweller, Finite Automata, Shooter Jennings, Death Grips vocalist MC Ride, X Marks the Pedwalk, Wumpscut, Haujobb, Orgy, Filter, Front Line Assembly, Orphx, Crystal Castles, AFI side project Blaqk Audio, and Mayhem vocalist Attila Csihar.
Their music has spawned "a litter of like-minded bands" including industrial rock project Nine Inch Nails who opened for Skinny Puppy for a short time on their 1988 VIVIsectVI tour Trent Reznor also acknowledged that Skinny Puppy's "Dig It" inspired the very first Nine Inch Nails track written "Down in It" Canadian synth-pop artist Grimes includes Skinny Puppy as an influence on her music having grown up in Vancouver's industrial music scene Sara Taylor of the EBM group Youth Code has said that the song "Worlock" was "one of the most influential songs" she had ever heard Other artists impacted by Skinny Puppy's music include Marilyn Manson Chester Bennington Moby Jonathan Davis Daron Malakian 3Teeth Foals vocalist Yannis Philippakis Al Jourgensen Chris Vrenna John Grant Mortiis Blush Response Celldweller Finite Automata Shooter Jennings Death Grips vocalist MC Ride X Marks the Pedwalk Wumpscut Haujobb Orgy Filter Front Line Assembly Orphx Crystal Castles AFI side project Blaqk Audio and Mayhem vocalist Attila Csihar