β-α-β motif Due to the chirality of their component amino acids, all strands exhibit right-handed twist evident in most higher-order β-sheet structures. In particular, the linking loop between two parallel strands almost always has a right-handed crossover chirality, which is strongly favored by the inherent twist of the sheet.See sections II B and III C, D in This linking loop frequently contains a helical region, in which case it is called a β-α-β motif. A closely related motif called a β-α-β-α motif forms the basic component of the most commonly observed protein tertiary structure, the TIM barrel.
β-α-β motif Due to the chirality of their component amino acids all strands exhibit right-handed twist evident in most higher-order β-sheet structures In particular the linking loop between two parallel strands almost always has a right-handed crossover chirality which is strongly favored by the inherent twist of the sheetSee sections II B and III C D in This linking loop frequently contains a helical region in which case it is called a β-α-β motif A closely related motif called a β-α-β-α motif forms the basic component of the most commonly observed protein tertiary structure the TIM barrel