Recently, researchers have been looking into means of reducing the general burden of immunosuppression. Common approaches include avoidance of steroids, reduced exposure to calcineurin inhibitors, increased coverance of vaccination for Vaccine-preventable diseaseCostantino, A.; Invernizzi, F.; Centorrino, E.; Vecchi, M.; Lampertico, P.; Donato, M.F. COVID-19 Vaccine Acceptance among Liver Transplant Recipients. Vaccines 2021, 9, 1314. https://doi.org/10.3390/vaccines9111314Costantino, A.; Morlacchi, L.; Donato, M.F.; Gramegna, A.; Farina, E.; Dibenedetto, C.; Campise, M.; Redaelli, M.; Perego, M.; Alfieri, C.; et al. Hesitancy toward the Full COVID-19 Vaccination among Kidney, Liver and Lung Transplant Recipients in Italy. Vaccines 2022, 10, 1899. https://doi.org/10.3390/vaccines10111899 and other means of weaning drugs based on patient outcome and function. While short-term outcomes appear promising, long-term outcomes are still unknown, and in general, reduced immunosuppression increases the risk of rejection and decreases the risk of infection. The risk of early rejection is increased if corticosteroid immunosuppression are avoided or withdrawn after renal transplantation.
Recently, researchers have been looking into means of reducing the general burden of immunosuppression. Common approaches include avoidance of steroids, reduced exposure to calcineurin inhibitors, increased coverance of vaccination for Vaccine-preventable diseaseCostantino, A.; Invernizzi, F.; Centorrino, E.; Vecchi, M.; Lampertico, P.; Donato, M.F. COVID-19 Vaccine Acceptance among Liver Transplant Recipients. Vaccines 2021, 9, 1314. https://doi.org/10.3390/vaccines911131.4Costantino, A.; Morlacchi, L.; Donato, M.F.; Gramegna, A.; Farina, E.; Dibenedetto, C.; Campise, M.; Redaelli, M.; Perego, M.; Alfieri, C.; et al. Hesitancy toward the Full COVID-19 Vaccination among Kidney, Liver and Lung Transplant Recipients in Italy. Vaccines 2022, 10, 1899. https://doi.org/10.3390/vaccines10111899 and other means of weaning drugs based on patient outcome and function. While short-term outcomes appear promising, long-term outcomes are still unknown, and in general, reduced immunosuppression increases the risk of rejection and decreases the risk of infection. The risk of early rejection is increased i?f corticosteroid immunosuppression are avoided or withdrawn after renal transplantation.