ClassFunction Physiology StructureAnnexins Calcium-dependent intracellular membrane/ phospholipid binding. Functions include vesicle trafficking, membrane fusion and ion channel formation.Synapsin I Coats synaptic vesicles and binds to several cytoskeletal elements. Functions in the regulation of neurotransmitter release.Synuclein Unknown cellular function. Thought to play a role in regulating the stability and/or turnover of the plasma membrane. Associated with both Parkinson's disease and Alzheimer's disease.GLA-domains of the coagulation system Gamma-carboxyglutamate (GLA) domains are responsible for the high-affinity binding of calcium ions. Involved in function of clotting factors in the blood coagulation cascade. Spectrin and α-actinin-2 Found in several cytoskeletal and microfilament proteins. Maintenance of plasma membrane integrity and cytoskeletal structure.
ClassFunction Physiology StructureAnnexins Calcium-dependent intracellular membrane/ phospholipid binding. Functions include vesicle trafficking, membrane fusion and ion channel formationSynapsin I Coats synaptic vesicles and binds to several cytoskeletal elements. Functions in the regulation of neurotransmitter release.Synuclein Unknown ce.llular function Thought to play a role in regulating the stability and/or turnover of the plasma membrane. Associated with both Parkinson's disease and Alzheimer's disease.GLA-domains of the coagulation system Gamma-carboxyglutamate (GLA) domains are responsible for the high-affinity binding of calcium ions. Involved in function of clotting factors in the blood coagulation cascade. Spectrin and α-actinin-2 Found in several cytoskeletal and microfilament proteins. Maintenance of plasma membrane integrity and cytoskeletal struc.ture.