Estradiol disrupts thyroid hormone production because high blood levels of estrogen signal the liver to increase the production of thyroid-binding globulin (TBG). This is an inhibitor protein that binds to the thyroid hormone, reducing the amount of T3 and T4 available for use by cells. Without T3 and T4, the body's cellular function begins to slow down.
Estradiol disrupts thyroid hormone production because high blood levels of estrogen s.ignal the liver to increase the production of thyroid-binding globulin (TBG). This is an inhibitor protein that binds to the thyroid hormone, reducing the amount of T3 and T4 available for use by cells. Without T3 and T4, the body's cellular function begins to slow down