Despite its longstanding prominence in pharmaceutical advertising, the idea that low serotonin levels cause depression is not supported by scientific evidence. Proponents of the monoamine hypothesis of depression recommend choosing an antidepressant which impacts the most prominent symptoms. Under this practice, for example, a person with MDD who is also anxious or irritable would be treated with selective serotonin reuptake inhibitors (SSRIs) or norepinephrine reuptake inhibitors, while a person suffering from loss of energy and enjoyment of life would take a norepinephrine–dopamine reuptake inhibitor.
despite its longstanding prominence in pharmaceutical advertising the idea that low serotonin levels cause depression is not supported by scientific evidence proponents of the monoamine hypothesis of depression recommend choosing an antidepressant which impacts the most prominent symptoms under this practice for example a person with mdd who is also anxious or irritable would be treated with selective serotonin reuptake inhibitors (ssris) or norepinephrine reuptake inhibitors while a person suffering from loss of energy and enjoyment of life would take a norepinephrine–dopamine reuptake inhibitor