In molecular biology, several analogues of the sugar backbone exist. Due to the low stability of RNA, which is prone to hydrolysis, several more stable alternative nucleoside/nucleotide analogues that correctly bind to RNA are used. This is achieved by using a different backbone sugar. These analogues include locked nucleic acids (LNA), morpholinos and peptide nucleic acids (PNA).
in molecular biology several analogues of the sugar backbone exist due to the low stability of rna which is prone to hydrolysis several more stable alternative nucleoside/nucleotide analogues that correctly bind to rna are used this is achieved by using a different backbone sugar these analogues include locked nucleic acids (lna) morpholinos and peptide nucleic acids (pna)