Cause The underlying cause of migraine is unknown. However, it is believed to be related to a mix of environmental and genetic factors. Migraine runs in families in about two-thirds of cases and rarely occur due to a single gene defect. While migraine attacks were once believed to be more common in those of high intelligence, this does not appear to be true. A number of psychological conditions are associated, including depression, anxiety, and bipolar disorder.The Headaches, pp. 246–247 thumb|Intracranial cavernous sinus: a potential site where dilation cerebral vessels can compress multiple cranial nerves. Success of the surgical migraine treatment by decompression of extracranial sensory nerves adjacent to vessels suggests that people with migraine may have anatomical predisposition for neurovascular compression that may be caused by both intracranial and extracranial vasodilation due to migraine triggers. This, along with the existence of numerous cranial neural interconnections, may explain the multiple cranial nerve involvement and consequent diversity of migraine symptoms.
Cause The underlying cause of migraine is unknown However it is believed to be related to a mix of environmental and genetic factors Migraine runs in families in about two-thirds of cases and rarely occur due to a single gene defect While migraine attacks were once believed to be more common in those of high intelligence this does not appear to be true A number of psychological conditions are associated including depression anxiety and bipolar disorderThe Headaches pp 246–247 thumb|Intracranial cavernous sinus a potential site where dilation cerebral vessels can compress multiple cranial nerves Success of the surgical migraine treatment by decompression of extracranial sensory nerves adjacent to vessels suggests that people with migraine may have anatomical predisposition for neurovascular compression that may be caused by both intracranial and extracranial vasodilation due to migraine triggers This along with the existence of numerous cranial neural interconnections may explain the multiple cranial nerve involvement and consequent diversity of migraine symptoms