Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled. By randomly allocating participants among compared treatments, an RCT enables statistical control over these influences. Provided it is designed well, conducted properly, and enrolls enough participants, an RCT may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied.
participants who enroll in rcts differ from one another in known and unknown ways that can influence study outcomes and yet cannot be directly controlled by randomly allocating participants among compared treatments an rct enables statistical control over these influences provided it is designed well conducted properly and enrolls enough participants an rct may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied