First stage The treatment for first-stage disease is fexinidazole by mouth or pentamidine by injection for T. b. gambiense. Suramin by injection is used for T. b. rhodesiense.
fIrst staGE ThE tREatMent FoR firsT-STaGe dIsEAse is fExINiDAzolE by MoUth or peNtAmIdIne By injectiOn FoR t. B. gAMBienSe. SurAmIN by inJecTiON Is Used For t. B. rhodEsieNse.