Geography Middletown is located in southern Dauphin County at (40.198491, -76.729326). Its southern border is along the Susquehanna River, and its eastern border is formed by Swatara Creek, across which is the borough of Royalton. Pennsylvania Route 230 (Main Street) leads northwest to the center of Harrisburg and southeast to Elizabethtown. Via the PA 283 expressway it is southeast to Lancaster. The Pennsylvania Turnpike (Interstate 76) passes through the northern part of the borough, but the nearest access is west near Highspire.
Geography Middletown is located in southern Dauphin County at (40198491 -76729326) Its southern border is along the Susquehanna River and its eastern border is formed by Swatara Creek across which is the borough of Royalton Pennsylvania Route 230 (Main Street) leads northwest to the center of Harrisburg and southeast to Elizabethtown Via the PA 283 expressway it is southeast to Lancaster The Pennsylvania Turnpike (Interstate 76) passes through the northern part of the borough but the nearest access is west near Highspire