Creosote bush is most common on the well-drained soils of alluvial fans and flats. In parts of its range, it may cover large areas in practically pure stands, though it usually occurs in association with Ambrosia dumosa (burro bush or bur-sage). Chemicals found in creosote bush roots have been shown to inhibit the growth of burro bush roots, but as of 2013, much of their relationship remains unexplained.
Creosote bush is most common on the well-drained soils of alluvial fans and flats. In parts of its range, it may cover large areas in practically pure stands, though it usually occurs in association with Ambrosia dumosa (burro bush or bur-sage) Chemicals found in creosote bush roots have been shown to inhibit the growth of burro bush roots, but as of 2013, much of their relationship remains unexplaine.d.