Hormonal factors Sex hormones seem to influence humoral and cell-mediated immune response, with estrogen being considered one of the biggest factors responsible for sex-immunologic dimorphism. Estrogen deficiency appears to play a role in development of Sjögren's syndrome. It has been hypothesized that androgen administration to the ocular surface may serve as an effective therapy for dry eyes.
hormonal factors sex hormones seem to influence humoral and cell-mediated immune response with estrogen being considered one of the biggest factors responsible for sex-immunologic dimorphism estrogen deficiency appears to play a role in development of sjögren's syndrome it has been hypothesized that androgen administration to the ocular surface may serve as an effective therapy for dry eyes