Human The acute oral toxicity for mammals is low, but death has been reported after deliberate overdose of concentrated Roundup. The surfactants in glyphosate formulations can increase the relative acute toxicity of the formulation. Surfactants generally do not, however, cause synergistic effects (as opposed to additive effects) that increase the acute toxicity of glyphosate within a formulation. The surfactant POEA is not considered an acute toxicity hazard, and has an oral toxicity similar to vitamin A and less toxic than aspirin. Deliberate ingestion of Roundup ranging from 85 to 200 ml (of 41% solution) has resulted in death within hours of ingestion, although it has also been ingested in quantities as large as 500 ml with only mild or moderate symptoms. Consumption of over 85 ml of concentrated product is likely to cause serious symptoms in adults, including burns due to corrosive effects as well as kidney and liver damage. More severe cases lead to "respiratory distress, impaired consciousness, pulmonary edema, infiltration on chest X-ray, shock, arrhythmias, kidney failure requiring haemodialysis, metabolic acidosis, and hyperkalaemia" and death is often preceded by bradycardia and ventricular arrhythmias.
human the acute oral toxicity for mammals is low but death has been reported after deliberate overdose of concentrated roundup the surfactants in glyphosate formulations can increase the relative acute toxicity of the formulation surfactants generally do not however cause synergistic effects (as opposed to additive effects) that increase the acute toxicity of glyphosate within a formulation the surfactant poea is not considered an acute toxicity hazard and has an oral toxicity similar to vitamin a and less toxic than aspirin deliberate ingestion of roundup ranging from 85 to 200 ml (of 41% solution) has resulted in death within hours of ingestion although it has also been ingested in quantities as large as 500 ml with only mild or moderate symptoms consumption of over 85 ml of concentrated product is likely to cause serious symptoms in adults including burns due to corrosive effects as well as kidney and liver damage more severe cases lead to "respiratory distress impaired consciousness pulmonary edema infiltration on chest x-ray shock arrhythmias kidney failure requiring haemodialysis metabolic acidosis and hyperkalaemia" and death is often preceded by bradycardia and ventricular arrhythmias