Immune regulation Under glutamine-deprived conditions, α-ketoglutarate promotes naïve CD4+ T cells differentiation into inflammation-promoting Th1 cells while inhibiting their differentiation into inflammation-inhibiting Treg cells thereby promoting certain inflammation responses.
Immune regulation Under glutamine-depr.ived conditions, α-ketoglutarate promotes naïve CD4+ T cells differentiation into inflammation-promo:ting Th1 cells while inhibiting their differentiation into inflammation-inhibiting Treg cells there,by promoting certain inflammation responses