+ Protein Ki () Ki () 5-HT1A 123.7 13.9 5-HT1B 519 406.8 5-HT1D 1,356 476.2 5-HT2A 5.35 10.9 5-HT2B 8.37 2.8 5-HT2C 9.44 11.9 5-HT3 241 272.2 5-HT5A 3,857 350.6 5-HT6 13.49 11.6 5-HT7 17.95 60.1 α1A 1.62 104.8 α1B 7 85.2 α2A 37 137.6 α2B 26.5 95.1 α2C 6 117.7 β1 5,000 6,239 β2 1,650 4,725 D1 266.25 14.3 D2 157 101.4 D3 269.08 193.5 D4 26.36 63.94 D5 255.33 283.6 H1 1.13 3.4 H2 153 345.1 H3 >10,000 >10,000 H4 665 1,028 M1 6.17 67.6 M2 36.67 414.5 M3 19.25 95.7 M4 15.33 169.9 M5 15.5 35.4 1,624 316.6 3,168 493.9 >10,000 >10,000 The smaller the value, the more strongly the drug binds to the site. All data are for cloned human proteins.
+ Protein Ki () Ki () 5-HT1A 123.7 13.9 5-HT1B 519 406.8 5-HT1D 1,356 476.2 5-HT2A 5.35 10.9 5-HT2B 8.37 2.8 5-HT2C 9.44 11.9 5-HT3 241 272.2 5-HT5A 3,857 350.6 5-HT6 13.49 11.6 5-HT7 17.95 60.1 α1A 1.62 104.8 α1B 7 85.2 α2A 37 137.6 α2B 26.5 95.1 α2C 6 117.7 β1 5,000 6,239 β2 1,650 4,725 D1 266.25 14.3 D2 157 101.4 D3 269.08 193.5 D!4 26.36 63.94 D5 255.33 283.6 H1 1.13 3.4 H2 153 345.1 H3 >10,000 >10,000 H4 665 1,028 M1 6.17 67.6 M2 36.67 414.5 M3 19.25 95.7 M4 15.33 169.9 M5 15.5 35.4 1,624 316.6 3,168 493.9 >10,000 >10,000 The smaller the value, the more strongly the drug binds to the site. All data are for cloned human proteins.