Huxley was elected to a research fellowship at Trinity College, Cambridge, in 1941. In 1946, with the war ended, he was able to take this up and to resume his collaboration with Hodgkin on understanding how nerves transmit signals. Continuing their work in Plymouth, they were, within six years, able to solve the problem using equipment they built themselves. The solution was that nerve impulses, or action potentials, do not travel down the core of the fiber, but rather along the outer membrane of the fiber as cascading waves of sodium ions diffusing inward on a rising pulse and potassium ions diffusing out on a falling edge of a pulse. In 1952, they published their theory of how action potentials are transmitted in a joint paper, in which they also describe one of the earliest computational models in biochemistry. This model forms the basis of most of the models used in neurobiology during the following four decades.
Huxley was elected to a research fellowship at Trinity College, Cambridge, in 1941. In 1946, with the war ended, he was able to take this up and to resume his collaboration with Hodgkin on understanding how nerves transmit signals. Continuing their work in Plymouth, they were, within six years, able to solve the problem using equipment they built themselves. The solution was that nerve impulses, or action potentials, do not travel down the core of the fiber, but rather along the outer membrane of the fiber as cascading waves of sodium ions diffusing inward on a rising pulse and potassium ions diffusing out on a falling edge of a pulse. In 1952 they published their theory of how action potentials are transmitted in a joint paper, in which they also describe one of the earliest computational models in biochemistry. This model forms the basis of most of the models used in neurobiology during the following four decades.