thumb|400px|The effects of temperature on enzyme activity. Top: increasing temperature increases the rate of reaction (Q10 coefficient). Middle: the fraction of folded and functional enzyme decreases above its denaturation temperature. Bottom: consequently, an enzyme's optimal rate of reaction is at an intermediate temperature.
thumb|400px|The effects of temperature on enzyme activity Top increasing temperature increases the rate of reaction (Q10 coefficient) Middle the fraction of folded and functional enzyme decreases above its denaturation temperature Bottom consequently an enzyme's optimal rate of reaction is at an intermediate temperature