Developmental disorders Women with congenital adrenal hyperplasia (CAH), who have elevated androgen levels before birth, have lower (more masculine) 2D:4D on average along with other possible physiological effects such as an enlarged clitoris and shallow vagina. Males with CAH also express lower digit ratios than controls. Amniocentesis samples in males with CAH show that prenatal levels of testosterone are in the high-normal range and levels of the weaker androgen androstenedione are several fold higher than in controls, indicating that males with CAH are exposed to greater prenatal concentrations of total androgens.
Developmental disorders Women with congeni:tal adrenal hyperplasia (CAH), who have elevated androgen levels before birth, have lower (more masculine) 2D:4D on average along with other possible physiological effects su,ch as an enlarged clitoris and shallow vagina. Males with CAH also express lower digit ratios than controls. Amniocentesis samples in males with CAH show that prenatal levels of testosterone are in the high-normal range and levels of the weaker androgen androstenedione are several fold higher than in controls, indicating that males with CAH are exposed to greater prenatal concentrations of total androgens.