A transmembrane protein, CD93, has been shown to be essential for fibronectin matrix assembly (fibrillogenesis) in human dermal blood endothelial cells. As a consequence, knockdown of CD93 in these cells resulted in the disruption of the fibronectin fibrillogenesis. Moreover, the CD93 knockout mice retinas displayed disrupted fibronectin matrix at the retinal sprouting front.
a transmembrane protein cd93 has been shown to be essential for fibronectin matrix assembly (fibrillogenesis) in human dermal blood endothelial cells as a consequence knockdown of cd93 in these cells resulted in the disruption of the fibronectin fibrillogenesis moreover the cd93 knockout mice retinas displayed disrupted fibronectin matrix at the retinal sprouting front