Transportation thumb|The Tuscaloosa Amtrak Station in 2003. The station is located one mile south of downtown Tuscaloosa. Tuscaloosa is connected to other parts of the country via air, rail, road and sea. The city lies at the intersection of several highways, including three federal highways (US 11, US 43, and US 82), three Alabama state highways (SR 69, SR 215, and SR 216) and two duplexed (conjoined) Interstates (I-20/I-59). Interstate 359 spurs off from I-20/I-59 and heads northward, ending in downtown Tuscaloosa.
Transportation thumb|The Tuscaloosa Amtrak Station in 2003. The station is located one mile south of downtown Tuscaloosa. Tuscaloosa is connected to other parts of the country via air, rail, road and sea. The city lies at the intersection of several highways, including three federal highways (US 11, US 43, and US 82), three Alabama state highways (SR 69, SR 215, and SR 216) and two duplexed (conjoined) Interstates (I-20/I-59). Interstate 359 spurs off from I-20/I-59 and heads northward, ending in downtown Tuscaloosa.