Tyrosine-specific protein kinases ( and ) phosphorylate tyrosine amino acid residues, and like serine/threonine-specific kinases are used in signal transduction. They act primarily as growth factor receptors and in downstream signaling from growth factors. Some examples include: Platelet-derived growth factor receptor (PDGFR) Epidermal growth factor receptor (EGFR) Insulin receptor and insulin-like growth factor 1 receptor (IGF1R) Stem cell factor (SCF) receptor (also called c-kit, see the article on gastrointestinal stromal tumor).
Tyrosine-specific protein kinases ( and ) phosphorylate tyrosine amino acid residues and like serine/threonine-specific kinases are used in signal transduction They act primarily as growth factor receptors and in downstream signaling from growth factors Some examples include Platelet-derived growth factor receptor (PDGFR) Epidermal growth factor receptor (EGFR) Insulin receptor and insulin-like growth factor 1 receptor (IGF1R) Stem cell factor (SCF) receptor (also called c-kit see the article on gastrointestinal stromal tumor)