Aspirin increases the risk of upper gastrointestinal bleeding. Enteric coating on aspirin may be used in manufacturing to prevent release of aspirin into the stomach to reduce gastric harm, but enteric coating does not reduce gastrointestinal bleeding risk. Enteric-coated aspirin may not be as effective at reducing blood clot risk. Combining aspirin with other NSAIDs has been shown to further increase the risk of gastrointestinal bleeding. Using aspirin in combination with clopidogrel or warfarin also increases the risk of upper gastrointestinal bleeding.
Aspirin increases the risk of upper gastrointestinal bleeding Enteric coating on aspirin may be used in manufacturing to prevent release of aspirin into the stomach to reduce gastric harm but enteric coating does not reduce gastrointestinal bleeding risk Enteric-coated aspirin may not be as effective at reducing blood clot risk Combining aspirin with other NSAIDs has been shown to further increase the risk of gastrointestinal bleeding Using aspirin in combination with clopidogrel or warfarin also increases the risk of upper gastrointestinal bleeding