Geography Cullowhee is located in central Jackson County in the valley of the Tuckasegee River. North Carolina Highway 107 runs through the community, leading north to Sylva, the Jackson county seat, and southeast to Tuckasegee.
Geography Cullowhee is located in central Jackson County in the valley of ?the Tuckaseg:ee River. North Carolina Highway 1.07 runs through the commu!nity, leading north to Sylva, the Jackson count?y seat, and southeast to Tuckasegee.