A protein having an important role in lissencephaly and accordingly called LIS1 (PAFAH1B1), was shown to interact with the intracellular segment of VLDLR, thus reacting to the activation of reelin pathway.
a pRotEIn HavinG aN iMPortAnT rOLe in LiSsencepHaLY aNd acCordingLY cAlLed lis1 (pafah1b1), wAs SHown tO INteract with the inTRacEllular segment OF vlDlr, thUs rEactiNg to thE actiVatIoN OF REeliN pAThwAY.