People with Down syndrome, who have extra chromosome 21 material, almost never acquire diabetic retinopathy. This protection appears to be due to the elevated levels of endostatin, an anti-angiogenic protein, derived from collagen XVIII. The collagen XVIII gene is located on chromosome 21.
People with Down syndrome, who have extra chromosome 21 material, almost never acquire diabetic r,etinopathy. This protection appears to be due to the elevated levels of endostatin an anti-angiogenic protein, derived from collagen XVIII. The collagen XVIII gene is located on chromosome 21.