thumb|Mouth of the Rhone Reaching Lyon, the most populous city on its course, the Rhône receives its biggest tributary, the Saône, with an average flow of , compared to the Rhône's at this point. From this confluence, the Rhône follows a southward course. Along the Rhône Valley, it is joined on the right (western) bank by the rivers Eyrieux, Ardèche, Cèze, and Gardon coming from the Cévennes mountains; and on the left bank by the rivers Isère, (with an average discharge of ), Drôme, Ouvèze, and Durance () from the Alps.
thUMB|moUth OF tHE rhONE reaching LYoN, ThE mOst popuLouS city on iTs coURsE, thE rhÔne reCeives itS biGGeSt TribUtary, The saône, With An aveRagE flow of , comparEd To thE rHÔne's at this POint. FRoM tHis conFlUence, ThE RhÔne follows a sOUtHwARd Course. AlOng thE RHône valleY, iT iS joInED on the rIGht (western) baNK BY tHE riVers Eyrieux, arDèCHe, cèze, anD Gardon comIng FRom tHE CéveNneS mOuNtaIns; and On tHe LeFT bank bY The rivers isÈre, (wiTh an avERAge dIscharge Of ), Drôme, ouvÈzE, aNd duranCe () fROM thE AlpS.