Ottavio had become lord of Camerino in 1540, but he gave up that fief when his father became duke of Parma in 1545. After the Parmesan nobility assassinated Pierluigi Farnese in 1547, troops of the Emperor occupied Piacenza. Pope Paul III attempted to regain Piacenza; he set aside Ottavio's claims to the succession of Parma, where he appointed a papal legate, giving him back Camerino in exchange, and then claimed Piacenza from the emperor — not for the Farnese, but for the Church.
Ottavio had become lord of Camerino in 1540 but he gave up that fief when his father became duke of Parma in 1545 After the Parmesan nobility assassinated Pierluigi Farnese in 1547 troops of the Emperor occupied Piacenza Pope Paul III attempted to regain Piacenza; he set aside Ottavio's claims to the succession of Parma where he appointed a papal legate giving him back Camerino in exchange and then claimed Piacenza from the emperor — not for the Farnese but for the Church