GATA-3 directly controls the expression of estrogen receptor (ER) and other genes associated with epithelial differentiation, and the loss of GATA-3 leads to loss of differentiation and poor prognosis due to cancer cell invasion and metastasis.
GATA-3 directly controls the expression of estrogen receptor (ER) and other genes associated with epithelial differentiation and the loss of GATA-3 leads to loss of differentiation and poor prognosis due to cancer cell invasion and metastasis