Effect on learning The hippocampus is a structure in the limbic system that receives projections from ipRGCs. It is required for the consolidation of short-term memories into long-term memories as well as spatial orientation and navigation. Depression and heightened serum corticosterone levels are linked to impaired hippocampal learning. Hattar and his team analyzed the T7 mice in the Morris water maze (MWM), a spatial learning task that places a mouse in a small pool of water and tests the mouse's ability to locate and remember the location of a rescue platform located just below the waterline. Compared to the T24 mice, the T7 mice took longer to find the platform in subsequent trials and did not exhibit a preference for the quadrant containing the platform. In addition, T7 mice exhibited impaired hippocampal long-term potentiation (LTP) when subjected to theta burst stimulation (TBS). Recognition memory was also affected, with T7 mice failing to show preference for novel objects in the novel object recognition test.
effect on learning the hippocampus is a structure in the limbic system that receives projections from iprgcs it is required for the consolidation of short-term memories into long-term memories as well as spatial orientation and navigation depression and heightened serum corticosterone levels are linked to impaired hippocampal learning hattar and his team analyzed the t7 mice in the morris water maze (mwm) a spatial learning task that places a mouse in a small pool of water and tests the mouse's ability to locate and remember the location of a rescue platform located just below the waterline compared to the t24 mice the t7 mice took longer to find the platform in subsequent trials and did not exhibit a preference for the quadrant containing the platform in addition t7 mice exhibited impaired hippocampal long-term potentiation (ltp) when subjected to theta burst stimulation (tbs) recognition memory was also affected with t7 mice failing to show preference for novel objects in the novel object recognition test