In contrast to the sudden fall in estradiol during menopause, the levels of total and free testosterone, as well as dehydroepiandrosterone sulfate (DHEAS) and androstenedione appear to decline more or less steadily with age. An effect of natural menopause on circulating androgen levels has not been observed. Thus specific tissue effects of natural menopause cannot be attributed to loss of androgenic hormone production.
in contrast to the sudden fall in estradiol during menopause the levels of total and free testosterone as well as dehydroepiandrosterone sulfate (dheas) and androstenedione appear to decline more or less steadily with age an effect of natural menopause on circulating androgen levels has not been observed thus specific tissue effects of natural menopause cannot be attributed to loss of androgenic hormone production