U.S. Route 220, a four-lane freeway, runs along the southern edge of the borough, with access from Exit 118 (Pennsylvania Route 150) to the south of town and from Exit 120 (Pennsylvania Route 44) to the east. The borough of Jersey Shore is to the east of Avis, and Williamsport is to the east via US 220, while Lock Haven, the Clinton county seat, is to the west.
US Route 220 a four-lane freeway runs along the southern edge of the borough with access from Exit 118 (Pennsylvania Route 150) to the south of town and from Exit 120 (Pennsylvania Route 44) to the east The borough of Jersey Shore is to the east of Avis and Williamsport is to the east via US 220 while Lock Haven the Clinton county seat is to the west