Another lifestyle approach to reduce LDL cholesterol has been minimizing total body fat, in particular fat stored inside the abdominal cavity (visceral body fat). Visceral fat, which is more metabolically active than subcutaneous fat, has been found to produce many enzymatic signals, e.g. resistin, which increase insulin resistance and circulating VLDL particle concentrations, thus both increasing LDL particle concentrations and accelerating the development of diabetes mellitus.
Another lifestyle approach to reduce LDL cholesterol has been minimizing total body fat in particular fat stored inside the abdominal cavity (visceral body fat) Visceral fat which is more metabolically active than subcutaneous fat has been found to produce many enzymatic signals eg resistin which increase insulin resistance and circulating VLDL particle concentrations thus both increasing LDL particle concentrations and accelerating the development of diabetes mellitus