Classes thumb|200px|class=skin-invert-image|Cortisol thumb|200px|class=skin-invert-image|Cortisone thumb|200px|class=skin-invert-image|Corticosterone thumb|200px|class=skin-invert-image|Aldosterone Glucocorticoids such as cortisol affect carbohydrate, fat, and protein metabolism, and have anti-inflammatory, immunosuppressive, anti-proliferative, and vasoconstrictive effects. Anti-inflammatory effects are mediated by blocking the action of inflammatory mediators (transrepression) and inducing anti-inflammatory mediators (transactivation). Immunosuppressive effects are mediated by suppressing delayed hypersensitivity reactions by direct action on T-lymphocytes. Anti-proliferative effects are mediated by inhibition of DNA synthesis and epidermal cell turnover. Vasoconstrictive effects are mediated by inhibiting the action of inflammatory mediators such as histamine. Mineralocorticoids such as aldosterone are primarily involved in the regulation of electrolyte and water balance by modulating ion transport in the epithelial cells of the renal tubules of the kidney.
classes thumb|200px|class=skin-invert-image|cortisol thumb|200px|class=skin-invert-image|cortisone thumb|200px|class=skin-invert-image|corticosterone thumb|200px|class=skin-invert-image|aldosterone glucocorticoids such as cortisol affect carbohydrate fat and protein metabolism and have anti-inflammatory immunosuppressive anti-proliferative and vasoconstrictive effects anti-inflammatory effects are mediated by blocking the action of inflammatory mediators (transrepression) and inducing anti-inflammatory mediators (transactivation) immunosuppressive effects are mediated by suppressing delayed hypersensitivity reactions by direct action on t-lymphocytes anti-proliferative effects are mediated by inhibition of dna synthesis and epidermal cell turnover vasoconstrictive effects are mediated by inhibiting the action of inflammatory mediators such as histamine mineralocorticoids such as aldosterone are primarily involved in the regulation of electrolyte and water balance by modulating ion transport in the epithelial cells of the renal tubules of the kidney