17 human proteins with Gla domains have been discovered; they play key roles in the regulation of three physiological processes: Blood coagulation: prothrombin (factor II), factors VII, IX, and X, and proteins C, S, and Z Bone metabolism: osteocalcin, matrix Gla protein (MGP), periostin, and Gla-rich protein. Vascular biology: Matrix Gla protein, growth arrest – specific protein 6 (Gas6) Unknown functions: proline-rich γ-carboxyglutamyl proteins 1 and 2, and transmembrane γ-carboxy glutamyl proteins 3 and 4.
17 human proteins with Gla domains have been discovered; they play key roles in the regulation of three physiological processes: Blood coagulation: prothrombin (factor II), factors VII, IX and X, and proteins C, S, and Z Bone metabolism: osteocalcin, matrix Gla protein (MGP), periostin, and Gla-rich protein. Vascular biology: Matrix Gla protein, growth arrest – specific protein 6 (Gas6) Unknown functions: proline-rich γ-carboxyglutamyl proteins 1 and 2, and transmembrane γ-carboxy glutamyl proteins 3 and 4