Atlantic and Cape May counties thumb|right|Route 49 westbound at milepost 49 in Estell ManorRoute 49 crosses the Tuckahoe River into Estell Manor, Atlantic County. It runs a short distance to the north of the Tuckahoe River and intersects CR 649 (Aetna Avenue) and CR 666 (Cape May Avenue) at Head of the River Church. The route crosses the Tuckahoe River into Upper Township, Cape May County, and intersects the eastern terminus of CR 548 (Tuckahoe Road), heading to the east. It intersects CR 632 (Marshallville Road) and then comes to CR 617 (Woodbine Road), which heads south to provide access to CR 557. Route 49 continues east into Tuckahoe, where it comes to a bridge over the Beesleys Point Secondary railroad line operated by the Cape May Seashore Lines railroad and intersects CR 659 (Railroad Avenue) before it ends at Route 50/CR 557.
Atlantic and Cape May counties thumb|right|Route 49 westbound at milepost 49 in Estell ManorRoute 49 crosses the Tuckahoe River into Estell Manor Atlantic County It runs a short distance to the north of the Tuckahoe River and intersects CR 649 (Aetna Avenue) and CR 666 (Cape May Avenue) at Head of the River Church The route crosses the Tuckahoe River into Upper Township Cape May County and intersects the eastern terminus of CR 548 (Tuckahoe Road) heading to the east It intersects CR 632 (Marshallville Road) and then comes to CR 617 (Woodbine Road) which heads south to provide access to CR 557 Route 49 continues east into Tuckahoe where it comes to a bridge over the Beesleys Point Secondary railroad line operated by the Cape May Seashore Lines railroad and intersects CR 659 (Railroad Avenue) before it ends at Route 50/CR 557