Several State Highways cross the county including, State Highway 7 which connects Lawton to Duncan. State Highway 17 starts at US Highway 62 and connects the city of Elgin to the town of Sterling and leads to Rush Springs in Grady County. State Highway 36 connects the towns of Chattanooga to Faxon and has its eastern terminus at Interstate 44. State Highway 49 enters the county from Kiowa County and becomes unsigned through the Wichita Wildlife refuge heading east. Leaving the refuge it becomes signed and leads through Medicine Park to its eastern terminus at Interstate 44. State Highway 58 connects to Carnegie in Caddo County to State Highway 49 near Medicine Park. State Highway 115 leads from Mountain View in Kiowa County through Meers to the Wichita Mountain Refuge. There it becomes unsigned as it leads to the south. Exiting the refuge, it becomes signed and leads to its southern terminus north of Cache on US Highway 62.
Several State Highways cross the county including, State Highway 7 which connects Lawton to Duncan. State Highway 17 starts at US Highway 62 and connects the city of Elgin to the town of Sterling and leads to Rush Springs in Grady County State Highway 36 connects the towns of Chattanooga to Faxon and has its eastern terminus at Interstate 44. State Highway 49 enters the county from Kiowa County and becomes unsigned through the Wichita Wildlife refuge heading east. Leaving the refuge it becomes signed and leads through Medicine Park to its eastern terminus at Interstate 44. State Highway 58 connects to Carnegie in Caddo County to State Highway 49 near Medicine Park. State Highway 115 leads from Mountain View in Kiowa County through Meers to the Wichita Mountain Refuge. There it becomes unsigned as it leads to the south. Exiting the refuge, it becomes signed and leads to its southern terminus north of Cache on US Highway 62.