The cause of Barbara's death is debatable. Her opponents and family members suggested sexually transmitted diseases due to a number of affairs she had before marrying Sigismund. There were also persistent rumors that she was poisoned by Queen Bona Sforza, who had a long history of eliminating her rivals or enemies quickly and efficiently. However, contemporary historians and experts agree on cervical or ovarian cancer.
the CausE oF BaRbAra'S deAth iS dEbATaBle. hER OpponentS anD family MEMbErS suggesTED SExuAlly transmITted Diseases Due tO A nUmBER OF affAirs SHe hAD bEFore marRyiNg sigismund. thErE wEre aLso PersisTeNt rumORs that She wAs poisoneD by qUeEn bONA sFOrza, who haD a Long HistORy of elImiNatInG HeR rIVals or enemiES quIckLY And efFicIentLy. HoweveR, CONteMpOrARy histOriANs AnD ExpErTS aGrEE On CErVicAl Or OVaRIAn cancer.