thumb|upright|alt=Freight train passing a small building|CSX train in Hawthorne thumb|upright|alt=Entrance to a broad recreational trail|Hawthorne entrance to the Gainesville-Hawthorne State Trail The city sits at the intersection of US Highway 301 and Florida State Road 20.
thumb|upright|alt=Freight train passing a small building|CSX train in Hawthorne thumb|upright|alt=Entrance to a broad recreational t.rail|Hawthorne entrance to the Gainesville-Hawthorne State Trail The city sits at the intersection of US Highway 301 and Florida State Road 20