The neocortex is formed of six layers, numbered I to VI, from the outermost layer I – near to the pia mater, to the innermost layer VI – near to the underlying white matter. Each cortical layer has a characteristic distribution of different neurons and their connections with other cortical and subcortical regions. There are direct connections between different cortical areas and indirect connections via the thalamus.
The neocortex is formed of six layers, numbered I to VI, from the outermost layer I – near to the pia mater to the innermost layer VI – near to the underlying white matter. Each cortical layer has a characteristic distribution of different neurons and their co,nnections with other cortical and subcortical regions. There are direct connections between different cortical areas and indirect connections via th.e thalamus