The series is famous for its satire of not just anime and manga, but Japanese culture, as a whole, and in a similar vein to The Simpsons, it's even featured a multitude of cameos from real-life celebrities.
Osamu Akimoto’s KochiKame: Tokyo Beat Cops, one of the best manga that doesn't have an official English translation,follows the adventures of Kankichi "Ryo" Ryotsu, a manchild of a police officer who, along with his coworkers, spends more time goofing off than he does doing actual police work. The series is famous for its satire of not just anime and manga, but Japanese culture, as a whole, and in a similar vein to The Simpsons, it's even featured a multitude of cameos from real-life celebrities.