If the quality of the extracted DNA is poor, all downstream steps can be compromised.
Purification, quantification and amplification of DNA and RNA are common methods used in many laboratory procedures across a wide variety of applications. Extraction of high-quality nucleic acid from cultured cells, animal or plant tissues, bacteria, body fluids and other sample types is a critical first step in most genomic analysis experiments. If the quality of the extracted DNA is poor, all downstream steps can be compromised.