8. A system for estimating a parameter, the system comprising: an imaging apparatus which obtains data that is reconstructed to obtain images; a parameter estimation processor programmed to: derive a parameter model function from the image data in which spillover is represented by a scaling factor [ f v ( 1 - f v ) ⁢ K 1 ] where f v is a spillover fraction and K 1 is an influx value; generate a N-dimensional grid, wherein N is a number of non-linear parameters or terms in the derived model function and a plurality of values are designated along each dimension; pre-calculate the one or more non-linear terms given the parameter model function and the designated values of the non-linear parameters; calculate one or more remaining model terms of the parameter model function; and display at least one of the one or more non-linear and remaining, linear model terms.
9. The system according to claim 8 , wherein the parameter model function is utilized to estimate myocardial blood flow.