1. A method of determining changes of an anatomical structure in a patient over time, the method comprising: accessing an image in a memory; segmenting a portion of the image containing an aneurysm; detecting the aneurysm in the segmented portion of the image; segmenting the detected aneurysm in the image; quantifying the segmented detected aneurysm in the image; visually presenting the segmented detected aneurysm; storing a location of the segmented detected aneurysm image data to the memory; accessing a second image in the memory; propagating the location of the segmented detected aneurysm onto the second image using bookmarking or registration; segmenting a second detected aneurysm in the second image; quantifying the second segmented detected aneurysm in the second image; determining temporal differences between the first segmented detected aneurysm and the second segmented detected aneurism; and visually presenting the temporal differences between the first segmented detected aneurysm and the second segmented detected aneurism.