1. A lesion characterization system ( 10 ), including: a processor ( 12 ) that receives anatomical image data for an image of a lesion volume ( 50 ), executes a segmentation protocol on the image data, and identifies intermediate segmentation results for the image data after one or more actions in the segmentation protocol are executed; a memory ( 14 ) that stores at least the image data, and intermediate and final segmentation results; and a user interface ( 16 ) on which at least the intermediate segmentation results and the final segmentation results are presented to a user for review.