1. A computer-automated monitoring system for early detection of incipient health problems in a monitored patient, comprising: a computer-accessible memory for storing a set of exemplary data observations of multiple vital signs obtained from said monitored patient comprising a personalized model of said patient: a data feed for receiving new data observations of said multiple vital signs from said monitored patient; a computer configured by a kernel-based modeling software module to generate an estimate of the value of at least one of said multiple vital signs, as a weighted combination of a subset of said exemplary data observations where said weights are determined from a kernel function comparison of said subset of exemplary data observations and a said received observation; said computer being further configured by a localization software module to select said subset of exemplary data observations based on at least some of the vital signs in said received observation; said computer being further configured by a residual analysis software module to compare said estimate to the corresponding measured value of the at least one of said multiple vital signs in said received data observation to generate a residual; and said computer being further configured by an alerting module to trigger an alert when said generated residual exceeds a threshold, and present said alert in a web-based interface usable by a medical practitioner for monitoring said patient for incipient health problems.