1. A computer-implemented method for hybrid analysis of a layout design comprising: using a processor for: performing rules-based analysis on at least a section of the layout design; identifying one or more portions of the section of the layout design using one or more heat maps or locations of hotspots based at least in part upon the rules-based analysis; ranking the one or more portions by analyzing said one or more heat maps or locations of hotspots based at least in part upon a ranking strategy, wherein the ranking strategy is based at least in part upon an amount of available resources for processing the one or more portions by models-based analysis such that at least one of the one or more portions are analyzed while another one of the one or more portions are not analyzed; and analyzing the one or more portions using the models-based analysis based at least in part upon the ranking; and storing a result from the analyzed one or more portions in a volatile or non-volatile computer-usable medium or displaying the result on a display device.