1. A multi-core processor comprising: a first register to reference a set of page tables, the set of page tables to provide a mapping of guest virtual addresses to guest physical addresses; a second register to reference an active set of extended page tables, including one of: a first set of extended page tables to provide a mapping of guest physical addresses to host physical addresses for a first virtual machine, the first set of extended page tables to reference a portion of host physical address space associated with the first virtual machine, and a second set of extended page tables to provide a mapping of guest physical addresses to host physical addresses for a second virtual machine, the second set of extended page tables to reference a portion of host physical address space associated with the second virtual machine; address translation logic to access the set of page tables and the set of extended page tables to translate a guest virtual address to a guest physical address and to translate the guest physical address to a host physical address in response to a memory access request including the guest virtual address; a translation look-aside buffer (TLB) to cache a plurality TLB entries, including guest physical address to host physical address translations; and execution logic, in response to a TLB invalidate instruction, to invalidate only TLB entries associated with the first virtual machine, independent of corresponding guest physical addresses.