1. A system for patient user-specific rehabilitation, the system comprising: one or more processors and a non-transitory computer-readable medium having executable instructions encoded thereon such that when executed, the one or more processors perform operations of: monitoring, using a Mobile Patient Monitor (MPM), sensor data obtained from a plurality of sensors in real-time to generate a quantitative assessment of a physical state and a motivational state of a user; generating, using a Virtual Patient (VP) unit, predictions related to the user utilizing user-specific biomechanical and neurocognitive models implemented with predictive simulations; generating rehabilitation guidance using a Virtual Coach (VC) unit through real-time communication with the VP unit; registering, using an Augmented Reality (AR) unit, video feed of the user with sensor data from the MPM and a set of simulation data from the VP unit; and conveying rehabilitation guidance instructions to the user through dialog-based user-VC interactions; and a lightweight exoskeleton worn by the user configured to convey real-time rehabilitation guidance to the user.