1. A method for Ileo-Cecal Valve (ICV) detection in an input 3D computed tomography (CT) volume, comprising: detecting initial box candidates for the ICV based on an ICV orifice in said input 3D CT volume; and detecting a box bounding the ICV in said 3D CT volume by sequentially detecting possible locations, scales, and orientations of the box bounding the ICV using incremental parameter learning based on said initial box candidates.