1. A method comprising: selecting a baseline electrode combination; delivering stimulation therapy to a patient via the baseline electrode combination; receiving patient feedback to the therapy delivery via the baseline electrode combination; selecting a therapy metric based on the patient feedback, the therapy metric comprising a quantifiable result of delivery of stimulation; and selecting an additional electrode combination based on information associating a plurality of electrode combinations with a respective value of the therapy metric, wherein the values of the therapy metric associated with the electrode combinations are generated by computer modeling of delivery of stimulation via the electrode combinations.