1. A computer executable model of a biological system in combination with a computer system including a memory and a processor, said computer executable model comprising: a plurality of biological representations stored in said memory and having a plurality of chemical level data points, each said chemical level data point representing a level of a chemical within a particular time period in a biological component; a means for determining unit impulse response from a first collection of said plurality of biological representations; a means for performing deconvolution having as inputs said unit impulse response and a second collection of said plurality of biological representations and producing as an output in vivo mean absorption data; a means for developing an in vitro in vivo correlation model having as inputs a third collection of said plurality of biological representations, each of said third collection of said plurality of biological representations chemical level data points representing in vitro ER data and said in vivo mean absorption data; and a means for validation of said in vitro in vivo correlation model.