1. A deductive multiscale simulation method comprising: (i) constructing a set of order parameters that model one or more structural characteristics of a macromolecule; (ii) simulating an ensemble of atomistic configurations for the macromolecule using instantaneous values of the set of order parameters; (iii) simulating thermal-average forces and diffusivities for the ensemble of atomistic configurations; (iv) evolving the set of order parameters via Langevin dynamics using the thermal-average forces and diffusivities; and (v) repeating steps (ii)-(iv) at each of a plurality of Langevin timesteps, wherein each of the plurality of Langevin timesteps is between 50 and 100 picoseconds.