1. A system for routing network traffic, comprising: a receiver configured to receive and process network traffic from one or more network traffic sources, the receiver comprising one or more transport destination synthesizers configured to selectively generate one or more synthetic destination transport responses; one or more application destination synthesizers configured to receive the network traffic from the receiver and selectively transmit to the receiver one or more synthetic destination application responses, the receiver being configured to transmit the one or more synthetic destination application responses to the one or more network traffic sources; one or more data diodes, each of which is coupled to a corresponding one of the one or more application destination synthesizers and configured to selectively provide one-way passage of the network traffic from the corresponding one of the one or more application destination synthesizers; one or more application source synthesizers corresponding to the one or more application destination synthesizers, each of the one or more application source synthesizers coupled to a corresponding one of the one or more data diodes and configured to receive the network traffic from the one or more data diodes; and a sender configured to receive the network traffic from the one or more application source synthesizers, the sender comprising one or more transport source synthesizers configured to selectively generate one or more synthetic source transport responses, wherein the sender is further configured to (i) transmit the one or more synthetic source transport responses to the one or more network traffic destinations, (ii) receive one or more destination responses from the corresponding one or more network traffic destinations, and (iii) transmit the one or more destination responses to the one or more application source synthesizers, wherein the one or more application source synthesizers are further configured to selectively generate and transmit, to the sender, one or more synthetic source application responses, and wherein the sender is further configured to transmit, to the corresponding one or more network traffic destinations, the network traffic and the one or more synthetic source application responses from the one or more application source synthesizers.