1. A method of preparing a compound of the formula comprising (i) attaching a conjugation component of the formula wherein R 2 is R 2a or R ap , to a solid support to form a compound of the formula (ii) when R 2 is R 2ap , converting and (iii) contacting with a conjugation component of the formula wherein R 3 is R 3a , R 3ap , hydrogen, a detectable label or an oligo; to form wherein: is a solid support material; are independently an oligo; R 1a and R 1b are complementary conjugation functionalities and L 1 is conjugate linker, and R 1a , R 1b , and L 1 are (a) R 1a is azido, R 1b is —C≡C—R 23 , or (b) R 1a is —NHR 23 , R 1b is carboxy, and L 1 is —NR 23 C(═O)—, or (c) R 1a is carboxy, R 1b is —NHR 23 , and L 1 is —C(═O)NR 23 —, or (d) R 1a is —NHR 23 , R 1b is halo, and L 1 is —NR 23 —, or (e) R 1a is —O—P(═O)(OH)(X), R 1b is hydroxy, and L 1 is —O—P(═O)(OH)—O—, or (f) R 1a is —O—P(═O)(OH)(X), R 1b is —NHR 23 , and L 1 is —O—P(═O)(OH)—NR 23 —, or (g) R 1a is —O—P(═O)(OH)(X), R 1b is thio, and L 1 is —O—P(═O)(OH)—S—, or (h) R 1a is halo, R 1b is thio, and L 1 is —S—, or (i) R 1a is R 1b is thio, and L 1 is or (j) R 1a is —C≡C—R 23 , R 1b is azido, and L 1 is or (k) R 1a is halo, R 1b is —NHR 23 , and L 1 is —NR 23 —, or (l) R 1a is hydroxy, R 1b is —O—P(═O)(OH)(X), and L 1 is —O—P(═O)(OH)—O—, or (m) R 1a is —NHR 23 , R 1b is —O—P(═O)(OH)(X), and L 1 is —NR 23 —P(═O)(OH)—O—, or (n) R 1a is thio, R 1b is —O—P(═O)(OH)(X), and L 1 is —S—P(═O)(OH)—O—, or (o) R 1a is —O—P(═O)(OH)SH, R 1b is —X, and L 1 is —O—P(═O)(OH)—S—, or (p) R 1a is —X, R 1b is —O—P(═O)(OH)SH, and L 1 is —S—P(═O)(OH)—O—, or (q) R 1a is —(CR 25 R 2s ) s C(═O)OR 23 , R 1b is —NHR 23 , L 1 is —(CR 25 R 25 ) s C(═O)NR 23 —, or (r) R 1a is —NHR 23 , R 1b is —(CR 25 R 25 ) s C(═O)OR 23 , L 1 is —NR 23 C(═O)—(CR 25 R 25 ), or (s) R 1a is thio, R 1b is halo, and L 1 is —S—, or (t) R 1a is thio, R 1b is and L 1 is (u) R 1a is —SH, R 1b is —O—P(═O)(OH)(O—(CH 2 ) n —SH) and L 1 is —S—S—(CH 2 )—O—P(OH)(═O)—O—; R 2a and R 2b are complementary conjugation functionalities and L 2 is conjugate linker, and R 2ap , R 2a , R 2b , and L 2 are (a′) R 2ap is halo, R 2a is azido, R 2b is —C≡C—R 23 , and L 2 is or (b′) R 2ap is —NR 23 Pr, R 2a is —NHR 23 , R 2b is carboxy, and L 2 is —NR 23 C(═O)—, or (c′) R 2ap is carboxy ester, R 2a is carboxy, R 2b is —NHR 23 , and L 2 is —C(═O)NR 23 —, or (d′) R 2ap is —NR 23 Pr, R 2a is —NHR 23 , R 2b is halo, and L 2 is —NR 23 —, or (e′) R 2ap is —OH, phosphate or phosphate ester, R 2a is —O—P(═O)(OH)(X), R 2b is hydroxy, and L 2 is —O—P(═O)(OH)—O—, or (f) R 2ap is —OH, phosphate or phosphate ester, R 2a is —O—P(═O)(OH)(X), R 2b is —NHR 23 , and L 2 is —O—P(═O)(OH)—NR 23 —, or (g′) R 2ap is —OH, phosphate or phosphate ester, R 2a is —O—P(═O)(OH)(X), R 2b is thio, and L 2 is —O—P(═O)(OH)—S—, or (h′) R 2a is —X, R 2b is thio, and L 2 is —S—, or (i′) R 2a is R 2b is thio, and L 2 is or (j′) R 2a is —C≡C—R 23 , R 2b is azido, and L 2 is or (k′) R 2a is halo, R 2b is —NHR 23 , and L 2 is —NR 23 —, or (l′) R 2a is hydroxy, R 2b is —O—P(═O)(OH)(X), and L 2 is —O—P(═O)(OH)—O—, or (m′) R 2a is —NHR 23 , R 2b is —O—P(═O)(OH)(X), and L 2 is —NR 23 —P(═O)(OH)—O—, or (n′) R 2a is thio, R 2b is —O—P(═O)(OH)(X), and L 2 is —S—P(═O)(OH)—O—, or (o′) R 2ap is —O—P(═O)(OH)SR 24 , R 2a is —O—P(═O)(OH)SH, R 2b is —X, and L 2 is —O—P(═O)(OH)—S—, or (p′) R 2a is —X, R 2b is —O—P(═O)(OH)SH, and L 2 is —S—P(═O)(OH)—O—, or (q′) R 2a is —(CR 25 R 25 ) s C(═O)OR 23 , R 2b is —NHR 23 , L 2 is —(CR 25 R 25 )C(═O)NR 23 —, or (r′) R 1a is —NHR 23 , R 2b is —(CR 25 R 25 ) s C(═O)OR 23 , L 2 is —NR 23 C(═O)—(CR 25 R 25 ) s —, or (s′) R 2a is thio, R 2b is halo, and L 2 is —S—, or (t′) R 2a is thio, R 2b is and L 2 is or (u′) R 2a is —SH, R 2b is —O—P(═O)(OH)(O—(CH 2 ) n —SH) and L 2 is —S—S—(CH 2 ) n —O—P(OH)(═O)—O—; X is selected from chlorine, bromine, fluorine, tosylate, mesylate, triflate, or dimethoxy triflate, n is 1, 2, 3, 4, 5, or 6; R 23 is selected from the group consisting of hydrogen, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl, cycloalkyl, substituted cycloalkyl, cycloalkenyl, substituted cycloalkenyl, cycloalkynyl, substituted cycloalkynyl, heteroaryl, substituted heteroaryl, heterocyclic, and substituted heterocyclic; Pr is an amino protecting group; R 24 is trityl or benzyl; R 25 is hydrogen or C 1-6 alkyl; n is 1, 2, 3, 4, 5, or 6; s is an integer of greater than 1; R 3ap is selected from the group consisting of halo, —OH, —NR 23 Pr, —O—P(═O)(OH)SR 24 , carboxy ester, phosphate and phosphate ester; and R 3a is selected from the group consisting of azido, —C≡C—R 23 , —NHR 23 , carboxy, halo, hydroxy, —C(═O)OR 23 , —O—P(═O)(OH)SH and —O—P(═O)(OH)Br; provided that R 2 does not react with R 1a or R 1b , and R 3 does not react with R 2a or R 2b ; - - - - - represents the point of connection to the part of the solid support-bound conjugated molecule that is closer to and represents the point of connection to the part of the solid support-bound conjugated molecule that is further away from