1. A system for quality assessment of optical colonoscopy images, the system comprising: an input device configured to acquire a series of images during an optical colonoscopy; and a computing device coupled in communication with the input device, the computing device including a processor platform comprising: a processor; and a memory containing instructions that, when executed by the processor, causes the processor to perform a process on each image of the series of optical images comprising: acquiring from the input device an input image from the series of images captured during the optical colonoscopy; forming a cell grid including a plurality of cells on the input image; performing an image transformation of the input image with each cell of the plurality of cells within the cell grid; reconstructing each cell to form a reconstructed image; computing a difference image of a sum of a plurality of differences between the input image and the reconstructed image; computing a histogram of the difference image; and applying a probabilistic classifier to the histogram to calculate an informativeness score for the input image.