1. A line replaceable unit (LRU) for an integrated modular avionics architecture, the LRU comprising at least one input/output interface and a plurality of connectors disposed within the LRU, wherein each connector includes at least one pin and said at least one pin of each connector is either unused or is connected to a single wire route bundle segregated from dissimilar wire route bundles according to segregation rules, and any other pins of each said connector that has a connected pin are precluded from connection to a wire route bundle dissimilar to said wire route bundle of the connected pin, and wherein hardware of one input/output interface is electrically connected within the LRU to one or more pins of each of at least two of the connectors.