1. A method, with an information processing system, in a wireless communication system, for suppressing interference, the method comprising: receiving, via each antenna of a plurality of receiver antennas, a transmission from a target wireless device; receiving, via each antenna of the plurality of receiver antennas, a transmission from an interfering wireless device; determining a set of pilot sequences associated with the interfering wireless device; determining a set of pilot sequences associated with the target wireless device; determining a set of weights for channel estimation associated with the set of pilot sequences associated with the interfering wireless device; determining a set of weights for channel estimation associated with the set of pilot sequences associated with the target wireless device; determining, in association with each antenna of the plurality of receiver antennas, a channel estimate for the target wireless device for each pilot sequence in the set of pilot sequences associated with the interfering wireless device and a channel estimate for the interfering wireless device for each pilot sequence in the set of pilot sequences associated with the interfering wireless device as a function of the received transmissions, the set of pilot sequences associated with the interfering wireless device, the set of pilot sequences associated with the target wireless device, the set of weights associated with the set of pilot sequences associated with the interfering wireless device, and the set of weights associated with the set of pilot sequences associated with the target wireless device; determining another set of weights, wherein the another set of weights comprises combining weights for each pilot sequence in the set of pilot sequences associated with the interfering wireless device as a function of the determined channel estimate of the target wireless device and the channel estimate of the interfering wireless device; and determining at least one pilot symbol estimate for the target communication device for each pilot sequence in the set of pilot sequences associated with the interfering wireless device as a function of the received transmission and the determined another set of weights, wherein, each combining weight of the another set of weights is applied to the received transmission from the target wireless device and the transmission from the interfering wireless device across all antennas of the plurality of receiver antennas in order to determine the at least one pilot symbol estimate.