1. A method for optimizing a circuit design over a set of scenarios, wherein each scenario is associated with a corner from a set of corners and a mode from a set of modes, the method comprising: determining, by computer, a subset of the set of scenarios based on a dominance relation on the set of corners such that if the circuit design meets a set of design constraints in each scenario in the subset of the set of scenarios, the circuit design is expected to meet the set of design constraints in each scenario in the set of scenarios; and wherein determining the subset of the set of scenarios based on the dominance relation on the set of corners includes removing a first scenario from the set of scenarios if the first scenario and a second scenario in the set of scenarios are associated with the same mode and a first corner associated with the first scenario is dominated by a second corner associated with the second scenario; and optimizing the circuit design over the subset of the set of scenarios.