1. A biological interface system comprising: a sensor comprising a plurality of electrodes for detecting multicellular signals emanating from one or more living cells of a patient; and a processing unit configured to receive the multicellular signals from the sensor and process the multicellular signals to produce a processed signal, the processing unit being configured to transmit the processed signal to a controlled device that is configured to receive the processed signal, wherein the system is configured to perform an integrated patient training routine to generate one or more system configuration parameters that are used by the processing unit to produce the processed signal, and wherein the system is configured such that the patient training routine is performed at least once during use of the system.