1. A method of executing an instruction, the method comprising: obtaining a perform frame management function (PFMF) machine instruction, the PFMF machine instruction comprising an opcode field, a first field designating a first register and a second field designating a second register; executing, by a pageable guest, the obtained PFMF machine instruction, the executing comprising: performing one or more operations on a guest frame designated by contents of the second register, said guest frame being non-resident in host memory, the performing being absent host intervention, and the one or more operations being specified in the first register, and wherein the one or more operations comprises a set storage key operation, and the performing comprises, based on the set storage key operation, associating a requested key value with a host page to enable interrogation of the requested key value while the host page is not host resident, and wherein the associating comprises including the requested key value in a page status table entry.