1. A method, comprising: selecting a diverse group of sera, the diverse group of sera having different characteristics; applying each of the diverse group of sera to at least one spot on a plurality of different biochips; performing mass spectrometry on each of said plurality of biochips; generating a biochip model based at least in part on the spectra obtained from the plurality of different sera and biochips; applying a test serum to a spot on a biochip; performing mass spectrometry on the test serum to obtain a spectrum associated with the test serum; mapping the spectrum obtained from said performing to the biochip model; and determining whether the spectrum maps to the biochip model.