1. An image signal processing system comprising: an image processing pipeline configured to collect statistics associated with fixed pattern noise of image data by: receiving a first frame of the image data comprising a plurality of pixels acquired using a digital image sensor; determining a sum of a first plurality of pixel values that correspond to at least a first portion of the plurality of pixels, wherein each pixel in at least the first portion of the plurality of pixels is disposed along a first axis within the frame of the image data; and storing the sum of the first plurality of pixel values in a memory, wherein the sum of the first plurality of pixel values represent the statistics.