1. A computer-implemented method for generating a three-dimensional representation of an object, the method comprising: receiving as input a first two-dimensional projection image; receiving as input acquisition data associated with said first two-dimensional projection image; processing said first two-dimensional projection image based upon said acquisition data to generate a three-dimensional volume of data providing said representation of said object, the volume of data comprising a plurality of voxels, each voxel having a value based upon at least one pixel of the two-dimensional projection image.