1. A computer-implemented method of manipulating image annotations, the method comprising: receiving an image of an individual's anatomy; automatically determining, using a processor, two or more annotations for anatomical features identified in the image of the individual's anatomy; determining a dependency between at least two of the two or more annotations for anatomical features identified in the image of the individual's anatomy, wherein the dependency is defined such that a change in a first annotation results in a corresponding change in a second annotation; receiving a modification to the first annotation; determining an update to a second annotation dependent from the first annotation, in response to the modification to the first annotation; determining a plurality of user interfaces displaying the modified first annotation or displaying the updated second annotation dependent on the first annotation; and outputting the plurality of user interfaces displaying the modified first annotation or displaying the updated second annotation dependent from the first annotation in an order based on the dependency between at least two of the two or more annotations.