1. A method comprising: locating a first region of a first image of a heart by clustering, the first region depicting a chamber of the heart, the chamber having a chamber shape; determining a boundary of the first region by contour tracing and retaining the traced contour overlapping the located first region; comparing a predetermined shape to the boundary, the predetermined shape having been determined without reference to the first image; determining a first plurality of parameters that, when applied to the predetermined shape, conforms the predetermined shape to the boundary and minimizes at least one error between the predetermined shape and the boundary; providing the first plurality of parameters to a classifier; and receiving from the classifier an indication of normality or abnormality of the chamber shape.