1. A method of improving efficiency of a refresh operation on a translation lookaside buffer (TLB) using an enhanced refresh PCI translation (RPCIT) instruction to refresh a translation lookaside buffer (TLB), the method comprising: analyzing, via a computer processor, a PCI command response block including at least one of a single-frame (SF) control bit field and a synchronization bypass (SB) control bit field; determining, via the computer processor, a single-frame TLB refresh operation is available based on a SF control bit existing in the SF control bit field; in response to detecting that the SF control bit indicates that the single-frame TLB refresh operation is available, determining, by the computer processor, a request to purge a translation for a single frame of the TLB in response to executing an enhanced RPCIT instruction configured to selectively perform one of the single-frame TLB refresh operation and a range-bounded TLB refresh operation; determining, by the computer processor, an absolute storage frame based on a translation of a PCI virtual address in response to the request to purge a translation for a single frame of the TLB; performing, by the computer processor, the single-frame TLB refresh operation to purge the translation for the single frame; and in response to detecting that the SF control bit indicates that the single-frame TLB refresh is unavailable, performing a range-bound refresh operation to purge multiple-addresses in the TLB.