1. Adaptive direct transaction method for interactive multi-media streaming to wirelessly locatable flat-panel network client group comprising steps: group analysis overlaying by at least one software-automated task manager implemented by at least one processor coupled wirelessly to a plurality of wirelessly locatable flat-panel client devices, each flat-panel client device comprising a wirelessly locatable sensor that enables real-time tracking of flat-panel mobile usage or location pattern, and at least one electronically programmed or reconfigured processor, and thereby enabling sensor monitoring and device analysis overlay of the plurality of flat-panel client devices by the at least one software-automated task manager by automatically comparing and classifying the plurality of flat-panel client devices hierarchically into at least one of sub-group or super-group of wirelessly locatable flat-panel client devices; and directed offering transacting by the at least one software-automated task manager with at least one flat-panel client device classified hierarchically by the at least one software-automated task manager into the at least one of sub-group or super group by wirelessly streaming interactive multi-media for offering directly to such classified flat-panel client device of the at least one of sub-group or super-group adaptively according to real-time tracking by least one software-automated task manager implemented by the at least one electronically programmed or reconfigured processor of each classified flat-panel client device mobile usage or location pattern; wherein at least one of the sensor comprises a global positioning system (GPS) receiver and accelerometer providing signal feedback that indicates out-of-range or movement alarm to the at least one software-automated task manager according to flat-panel client device product model, upgrade or defect; monitoring by the at least one software-automated task manager the GPS receiver or accelerometer of the plurality of flat-panel client devices and hierarchically grouping the plurality of flat-panel client devices based on real-time tracking of flat-panel mobile usage or location pattern; contextually mapping by the at least one software-automated task manager the at least one sub-group or super-group to a single interactive multi-media stream, thereby enabling the directed offering of the single interactive multi-media stream to flat-panel client devices grouped in a hierarchical manner; dynamically enabling by the at least one software-automated task manager adaptive direct transaction for interactive multi-media streaming singly to wirelessly locatable flat-panel network client device of the at least one of sub-group or super-group in real-time according to media-, mobile- or bio-sensing of each client device, processing by the at least one software-automated task manager using group overlay software one or more media-,mobile- and bio-sensor database associated with each client device in the network client device the at least one of sub-group or super-group, classifying by the at least one software-automated task manager each client device adaptively into the network client device of the at least one of sub-group or super-group by using said group overlay software to compare each client device media-, mobile-, or bio-sensor data and said group overlay software; enabling direct offering transaction automatically via single interactive multi-media stream to each client device in the network client device sub-group or super-group adaptively according to each client device media-, mobile-, and/or bio-sensor data; using by the at least one of said plurality of wirelessly locatable flat-panel client devices said at least one software-automated task manager to provide telemedicine diagnostic computation or communication service adaptively according to at least one of: medical condition, bio-sensor condition or demographic attribute associated with at least one of: equivalent or substantially similar personal protein or genetic sequence, said personal protein or genetic sequence is received as at least one of: sensor-sampled or input-verified personal protein or genetic sequence, thereby providing the at least one directed offering transaction by said at least one software-automated task manager adaptively according to said at least one of: medical condition, bio-sensor condition or demographic attribute associated with said at least one of: equivalent or substantially similar one or more sensor-sampled or input-verified personal protein or genetic sequence.