1. A method comprising: acquiring a video sequence, including a plurality of video frames, of an eye of a patient; selecting and assigning weights to at least one static eye-related parameter and at least one dynamic eye-related parameter of a plurality of eye-related parameters, including a baseline pupil size, a maximum change in size of a pupil, an average velocity of constriction of the pupil, a maximum velocity of constriction of the pupil, latency of constriction of the pupil, and a velocity of re-dilation of the pupil, based on which physiologic perturbation of a patient, of a plurality of selectable physiologic perturbations, is selected to be determined; and determining, using processing circuitry, whether the patient has the selected physiologic perturbation based on the selected at least one static eye-related parameter and the at least one dynamic eye-related parameter and the weights assigned to the at least one static eye-related parameter and the at least one dynamic eye-related parameter.