1. A computer-implemented method for navigating current and reference images and associated evidence comprising: loading a current image and a reference image for review via a navigator interface based on a time entry selection by a user; registering one or more markers indicating clinical findings or evidence with at least one of the current image and the reference image and associated regional information; displaying the one or more markers in conjunction with the current image and the reference image; providing a synopsis of information associated with a selected marker upon selection of the marker by a user; and allowing a user to navigate through image and marker data over time by selecting each of a plurality of time entries to display images and associated markers for user review.