1. Process Control System, comprising an expert system that models the actions of an operator of the process over an operating region of the process, that represents a set of rules for actions to be taken by an operator upon the occurrence of predetermined conditions in the operation of the process in order to meet given process targets, and that takes the action when one of the predetermined conditions exist to control the operation of the process by changing one or more of process control variables that control the process following the set of rules; and, a model predictive control system that is operable to receive inputs representing measured variables of the process and to predict on an output of the model predictive control system predicted control values for controlled variables that control the process; characterized in, that the model predictive control system and the expert system are series connected in such a way that predicted control values of the model predictive control system serve as process targets for the expert system.