1. A system comprising: one or more of a computer processor and a computer storage device configured to: store an engine simulation model of an engine; incorporate an inferential sensor module into the engine simulation model; and calibrate one or more parameters for the inferential sensor module using one or more of engine measurement data and the engine simulation model, such that a difference between an inferred signal predicted by the inferential sensor module and a signal measured on the engine is minimized; wherein the engine simulation model is calibrated using measured on-engine data, the on-engine data comprising model input signals and measurements of a plurality of engine properties.