1. A system, comprising: a plurality of processing actors, each including a computer processor, wherein the plurality of processing actors includes an imaging device from a group consisting of computed tomography, positron emission tomography, magnetic resonance imaging, ultrasound and X-ray; and an orchestrator, including a processor, configured to orchestrate closed-loop implementation of a workflow plan by the plurality of processing actors, wherein the processor: generates the workflow plan, in electronic format, based on an imaging procedure for a subject and the imaging device, wherein the workflow plan includes at least one action including performing the imaging procedure with the imaging device; creates a schedule, in electronic format, for the imaging procedure; conveys the schedule to at least one actor of the plurality of processing actors, wherein the at least one actor includes a computing device; transmits, in response to arrival of the scheduled date and over a network, a notification signal to the imaging device being used to perform the imaging procedure, wherein the notification signal causes the imaging device to load an identified imaging protocol for the imaging procedure to configure itself to scan the subject; and modifies the workflow plan to indicate the imaging procedure has been performed in response to completion of the imaging procedure, wherein the workflow plan includes at least one additional action to perform.