1. A neuro-stimulation system, comprising: an electrode array having an implantable support member configured to be implanted into a patient and a plurality of therapy electrodes carried by the support member; a pulse system operatively coupled to the therapy electrodes, the pulse system delivering a stimulus to the therapy electrodes; and a controller operatively coupled to the pulse system, the controller including a computer operable medium containing instructions that generate command signals that define the stimulus delivered by the pulse system and determine a desired configuration for the therapy electrodes and/or a desired stimulus to be delivered to the therapy electrodes based upon feedback input to the controller.