1. A method to correlate a fluorescence microscopy image with an electron microscopy image in a sub diffraction resolution environment, comprising: under control of a processor and memory configured with executable instructions, receiving a first dataset representing a fluorescence microscopy capture containing a plurality of feature markers; receiving an electron microscopy capture containing a plurality of feature markers; registering a plurality of data points of the first dataset with the electron microscopy image to align the plurality of feature markers of the first dataset with the plurality of feature markers of the electron microscopy capture; and forming a combined visualization based upon the registering of the plurality of data points of the first dataset and the electron microscopy capture.