1. A computer-accessible memory medium comprising program instructions, wherein the program instructions are executable to: receive a graphical program, wherein the graphical program comprises a first portion having a first computational model and a second portion having a second computational model, wherein the first portion of the graphical program comprises a first plurality of interconnected nodes that visually indicates functionality of the first portion of the graphical program, and wherein the second portion of the graphical program comprises a second plurality of interconnected nodes that visually indicates functionality of the second portion of the graphical program; and generate a hardware description based on the graphical program, wherein the hardware description describes a hardware implementation of the graphical program, and wherein the hardware description is configured to configure a programmable hardware element to implement functionality of the graphical program.