1. A physical integrated circuit (IC) design tool for analyzing an IC design, the design tool comprising: instructions of one or more software modules stored in a storage device and executable by a processor, the instructions of the one or more software modules including instructions for a user interface (UI) software module to read a design uncertainties file including a plurality of predetermined IC design uncertainties, wherein the plurality of predetermined IC design uncertainties of the design uncertainties file includes at least two of the set of lithography, semiconductor processing, etching, chemical-mechanical polishing, dopant fluctuations, placement, orientation, surrounding geometry, Intra-Chip positional, Chip-to-Chip positional, operational, voltage, temperature, and aging, to communicate the plurality of predetermined IC design uncertainties to a user for selection, and to receive one or more user-selected IC design uncertainties from the user; and a design analysis software module in communication with the UI software module to receive the one or more user-selected IC design uncertainties, the design analysis software module to analyze a circuit in response to the one or more user-selected IC design uncertainties.