1. A computerized image guided pre-colony selection method comprising the steps of: a) Input into computer memory at least one pre-colony cell image; b) Perform by a computer pre-colony region recognition using the pre-colony cell image to generate pre-colony region context output; c) Perform by a computer pre-colony region context measurement using the pre-colony region context to generate at least one pre-colony region context feature output wherein the pre-colony region context feature is from a set consisting of seed cell features, adjacent region context features and background context features; d) Perform by a computer pre-colony decision using the pre-colony region context feature to generate pre-colony selection decision output.