1. A method of executing a machine instruction in a central processing unit, the method comprising: obtaining, by a processor, a machine instruction for execution, the machine instruction being defined for computer execution according to a computer architecture, the machine instruction comprising: at least one opcode field to provide an opcode, the opcode identifying a Vector Find Element Not Equal operation; an extension field to be used in designating one or more registers; a first register field combined with a first portion of the extension field to designate a first register, the first register comprising a first operand; a second register field combined with a second portion of the extension field to designate a second register, the second register comprising a second operand; a third register field combined with a third portion of the extension field to designate a third register, the third register comprising a third operand; a mask field, the mask field comprising one or more controls to be used during execution of the machine instruction; and executing the machine instruction, the execution comprising: determining whether the mask field includes a zero element control set to indicate a search for a zero element; based on the mask field including the zero element control set to indicate the search for a zero element, searching the second operand for a zero element, the searching providing a null index, the null index including one of an index of a zero element found in the search or an indication of no zero elements found; comparing one or more elements of the second operand with one or more elements of the third operand for inequality, the comparing providing a compare index, the compare index including one of an index of an unequal element based on the comparing finding an unequal element or an indication of no inequality based on the comparing finding no unequal elements; providing a result, the result based on whether the search for zero element was performed, wherein the result includes one of: based on not performing the search for zero element, the result includes the compare index; or based on performing the search for zero element, the result includes one of the compare index or the null index.