1. A computer-implemented system for inducing or more deeply integrating a change of state in a subject, comprising: at least one data input device that samples initial subject data, at a first time, the initial subject data including at least genetic or epigenetic expression data relating to an initial state of the subject; a data storage device that stores the initial subject data in association with a subject record associated with the subject; a rules engine that determines, based on at least a subset of information stored in the subject record, one or more challenges to be presented to the subject that are designed to induce a change of state in the subject from the initial state to a desired state; a challenge presentation device that presents the one or more challenges to the subject at a second time, wherein the at least one data input device also samples responsive subject data at a third time, the responsive subject data including at least genetic or epigenetic expression data indicting a response by the subject to the one or more challenges, and wherein the data storage device stores a record of the one or more challenges and the responsive subject data in association with the subject record; and a recursive data analysis module that analyzes the subject record to determine changes in the response subject data from the initial subject data and that updates the rules engine, wherein the updated rules engine determines one or more additional challenges that have an increased likelihood of inducing a change of state in the subject from the initial state to the desired state, and wherein the challenge presentation device presents the one or more additional challenges to the subject at a fourth time.