1. In a computer system comprising at least one processor, at least one storage means and at least one input device, a method of identifying suspicious anomalies in an anatomical colon under study, comprising: a. by means of at least one input device, acquiring a plurality of images of the anatomical colon; b. by means of at least one processor, registering at least a portion of a first acquired anatomical colon image with respect to at least a portion of a second acquired anatomical colon image; c. by means of at least one processor, for said first and second acquired anatomical colon images, identifying at least one candidate suspicious anomaly in said acquired anatomical colon image; d. by means of at least one processor, for at least one said candidate suspicious anomaly in the registered first acquired anatomical colon image, determining that at least one candidate suspicious anomaly in the registered second acquired anatomical colon image corresponds to said candidate suspicious anomaly in the registered first acquired anatomical colon image, whereby the corresponding suspicious anomalies constitute a matched set; e. by means of at least one processor, classifying at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies as belonging to a true positive class; and f. by means of at least one storage means, storing information with respect to at least one candidate suspicious anomaly in a matched set of candidate suspicious anomalies classified as belonging to a true positive class.