1. A computer-implemented method of deterministic multithreaded execution, the method comprising: executing one or more threads via one or more execution pipelines, wherein each thread is configured to access an isolated memory region; and in response to determining that all of the one or more threads have detected end of execution quantum events, synchronizing the isolated memory regions; wherein the end of execution quantum events include an instruction count event, wherein the instruction count event indicates execution of a predetermined number of machine instructions by a thread, and wherein the number of machine instructions includes memory instructions and arithmetic instructions.