1. A method for optimizing performance of an electronic signal monitoring study comprising: assessing study criteria to determine an appropriate noise reduction circuit; selecting via a computer-implemented user interface an appropriate noise reduction circuit from a plurality of noise reduction circuits in an electronic signal monitoring system, wherein at least one of the plurality of noise reduction circuits is a right leg drive circuit; connecting ECG cables from the electronic signal monitoring system to a patient; and obtaining a noise reduced ECG trace through operation of the electronic signal monitoring system using the noise reduction circuit.