1. A diabetes self-care system, comprising: (a) a blood glucose meter; (b) a portable microprocessor-based unit signal coupled with the blood glucose meter such as to be capable of advising a user to measure a blood glucose level by downloading blood glucose measurement data into the portable microprocessor-based unit, wherein said portable microprocessor based unit comprises a display screen configured to present to said user an interactive presentation; (c) said blood glucose measurement data being used as input data for a program of instructions running on the portable microprocessor-based unit; and (d) said program of instructions including instructions (i) to advise said user to inject insulin according to an insulin plan, (ii) present to said user on said display screen (a) said blood glucose measurement data and (b) information to educate said user regarding management of diabetes, (iii) receive from said user responses confirming said blood glucose level has been measured, and (iv) positively reinforce compliance with a diabetes management plan by providing incentives in said interactive presentation on said display screen in response to said blood glucose level being within an optimal range.