1. A method for use with an implantable system including a lead having multiple electrodes implantable proximate to a patient's left ventricular (LV) chamber, the method comprising: simultaneously delivering pacing pulses over corresponding pacing vectors, the pacing vectors defined by electrodes proximate to the LV chamber; recording evoked responses that are responsive to the pacing pulses, the evoked responses associated with the corresponding pacing pulses and measured over separate corresponding sensing channels; comparing the evoked responses to at least one template, the at least one template representing local capture of a local LV tissue region along one or more of the corresponding pacing vectors, the comparison used to determine whether the pacing pulses achieved local capture along the corresponding pacing vectors; and updating at least one of the pacing pulses or the pacing vectors based on the comparison of the evoked responses to the at least one template in order to determine a local capture threshold for the corresponding pacing vectors.