1. A method for determining and responding in real-time to an increased risk of death relating to a patient with epilepsy, comprising: receiving cardiac data into a medical device; determining, using the medical device, at least one cardiac index, said at least one cardiac index being based upon the cardiac data; determining, using the medical device, an increased risk of death associated with epilepsy if the at least one cardiac index is an extreme value; issuing automatically a warning of the occurrence of the increased risk of death; and logging automatically information related to the increased risk of death.