1. A computer-implemented method of assaying a cell comprising: providing said computer with a reference database, wherein the reference database comprises cell datasets produced from characteristic data including global profile information for at least one-hundred fifty known cell lines, tissues, or primary cells and at least one dataset produced for each of human embryonic stem cells, human induced pluripotent stem cells and human somatic multipotent cells; receiving a test dataset in said computer, wherein the test dataset comprises data including global profile information for a cell line, tissue, or primary cell of previously unknown pluripotency; merging the test dataset into the reference database producing an updated reference database; and performing in said computer unsupervised classification of the updated reference database thereby producing a computed label classification of the test dataset, wherein the computed label classification includes an indication of whether or not the cell line, tissue, or primary cell in the test dataset is pluripotent or contains pluripotent cells.