1. A computer-implemented method of analyzing a document with a managed research domain, comprising: parsing text of a first document to identify one or more assertions made by the text of the first document; for each identified assertion: generating assertion metadata describing a relationship between one or more topics in the assertion, and determining a set of documents stored by the managed research domain that contain assertions regarding the topics identified in the assertion; and providing an indication to a user of the set of documents that contain assertions regarding the topics identified in the one or more assertions.