1. A system that facilitates automated diagnosis of diseases, comprising: an alignment component that aligns a 2-dimensional (2D) slice of an optical coherence tomography (OCT) image of a retina to produce an aligned slice, wherein the aligned slice comprises an approximately horizontal image of the retina; a feature construction component that determines at least one global representation and at least one local descriptor based at least in part on the aligned image, wherein the at least one local descriptor comprises a local binary pattern (LBP)-based feature; and a classification component that comprises one or more classifiers, wherein each classifier classifies the aligned image into one of a plurality of categories associated with at least one ocular pathology.