1. A method for evaluating unit processes for a semiconductor manufacturing process, comprising: performing a first set of tests corresponding to a semiconductor manufacturing operation in a combinatorial manner according to corresponding input variables in order to evaluate material properties on a first substrate wherein the semiconductor manufacturing operation is one of a wet chemical operation, a dry processing operation, or a deposition operation; inputting results of the first set of tests and the corresponding input variables into a mathematical model to derive coefficients relating the input variables to the results; defining sets of varied input variables; combining sets of the varied input variables with the coefficients to derive a predicted output for each of the sets; selecting a portion of the sets of the varied input variables; and performing a second set of tests in a combinatorial manner according to the portion of the sets of the varied input variables on a second substrate.