1. A method for controlling movement of a polynucleotide using voltage feedback control, the method resulting in identifying the sequence of a polynucleotide, the method comprising the steps of: providing two separate adjacent chambers comprising a medium, an interface between the two chambers, the interface comprising a material having at least channel therethrough and wherein one chamber is on the cis-side of the interface and the other chamber is on the trans-side of the interface, the channel so dimensioned as to allow sequential monomer-by-monomer passage from the cis-side of the channel to the trans-side of the channel of only one polynucleotide strand at a time; providing an enzyme having binding activity for a polynucleotide; providing a blocking oligomer; providing a polynucleotide complex, wherein a portion of the polynucleotide complex is double-stranded and a portion is single-stranded; providing a complimentary oligomer, wherein the complimentary oligomer is complementary to a portion of the single stranded polynucleotide; providing a substrate; introducing the polynucleotide complex into one of the two chambers; introducing the blocking oligomer into the same chamber; allowing the blocking oligomer to bind to the polynucleotide complex; introducing the enzyme into the same chamber; introducing the complementary oligomer into the other chamber; applying a potential difference between the two chambers, thereby creating a first polarity, the first polarity causing the single stranded portion of the polynucleotide to transpose through the channel to the trans-side thereby stripping the blocking oligomer from the polynucleotide complex; measuring the electrical current through the channel thereby detecting the polynucleotide; decreasing the potential difference a first time, thereby creating a second polarity; allowing the complementary oligomer to bind to the single-stranded polynucleotide; reversing the potential difference, thereby creating a third polarity; providing conditions to allow the enzyme to bind to the polynucleotide complex; providing conditions to allow the enzyme to incorporate substrate into the polynucleotide, thereby increasing length of the double-stranded portion; reversing the potential difference a second time; measuring the electrical current through the channel, thereby detecting a polynucleotide having incorporated substrate or a polynucleotide bound to the enzyme; repeating any one of the steps, thereby controlling the synthesis of the polynucleotide.