1. A computer-based system for integrating a computerized business system, a computerized manufacturing system, and a laboratory information management system wherein the computerized business system creates a work order containing target data specifying a product to be manufactured, and the computerized manufacturing system requires a setpoint to manufacture the product, comprising: a business systems interface configured to receive the work order from the computerized business system and to extract the target data from the received work order; an event response processor coupled to said business system interface and configured to generate the setpoint by applying at least one rule to the target data, said at least one rule allowing computation of the setpoint to meet specific requirements of the computerized manufacturing system; and a computerized laboratory systems interface configured to provide sample correspondence data derived from said work order to said laboratory information management system.