1. A system, comprising: a set of isolated polynucleotides or isolated polypeptides that specifically hybridize or bind to a panel of gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) biomarkers, wherein the panel comprises a plurality of GEP-NEN biomarkers selected from the group consisting of: AKAP8L, ATP6V1H, BNIP3L, C21orf7, COMMD9, ENPP4, FAM131A, FLJ10357, GLT8D1, HDAC9, HSF2, LEO1, MORF4L2, NOL3, NUDT3, OAZ2, PANK2, PHF21A, PKD1, PLD3, PQBP1, RNF41, RSF1, RTN2, SMARCD3, SPATA7, SST1, SST3, SST4, SST5, TECPR2, TRMT112, VPS13C, WDFY3, ZFHX3, ZXDC, ZZZ3, APLP2, CD59, ARAF1, BRAF1, KRAS, and RAF1 gene products.