1. A deductive multiscale simulation method comprising: (i) constructing a set of order parameters that model one or more structural characteristics of a macromolecule; (ii) simulating an ensemble of atomistic configurations for the macromolecule using instantaneous values of the set of order parameters; (iii) simulating thermal-average forces and diffusivities for the ensemble of atomistic configurations; and (iv) evolving the set of order parameters via Langevin dynamics using the thermal-average forces and diffusivities.