1. A method for computer aided detection, the method comprising: determining a pixel threshold value for an analysis of an image selected by a user, wherein the image includes a plurality of pixels; determining a segmentation setting for the analysis, the segmentation setting specifying a size of a portion of the image to be used during the analysis; analyzing the image by performing a comparison between a first and second segment of the image based on the pixel threshold value and the segmentation setting; and identifying potential abnormalities in the image based on the analysis.