1. A method of treating a patient in need of pain therapy comprising administering a vanilloid receptor-1 (VR1) agonist to the patient, wherein the VR1 agonist is resiniferatoxin, and the resiniferatoxin is administered to a ganglion or nerve root by intraganglionic injection in an amount from 50 nanograms to 500 micrograms, in a volume sufficient to achieve pain relief, wherein the pain in the patient is caused by a disease or a neuralgia.