1. An X-ray imaging system comprising: an X-ray source configured to provide X-ray radiation and having an associated focal spot; a detector configured to generate a digital image representing attenuation of the X-ray radiation as it passes through a subject; an image enhancement component, implemented as machine executable instructions stored on a non-transitory computer readable medium and executed by an associated processor and configured to apply a selected one of a plurality of separable deconvolution kernels, each derived from an estimate of a point spread function associated with the focal spot as a separable function, to the digital image; and a user interface that displays the digital image to a user.