1. A method of executing an instruction, the method comprising: executing, by a guest processor, a perform frame management function (PFMF) instruction, the PFMF instruction comprising an address for locating a guest frame and a frame management function indication, the frame management function indication specifying at least one of a clear frame control or a set key control, the executing comprising: determining, based on the frame management function indication specifying the clear frame control, whether the guest frame is assigned to host memory; based on determining the guest frame is assigned to host memory, clearing the guest frame; and based on determining the guest frame is not assigned to host memory, performing one of generating a translation exception or logically clearing the guest frame.