1. A composition for ameliorating symptoms and/or treating one or more neurodegenerative diseases, neurological disorders, anxiety disorders or combinations thereof in a subject comprising: one or more spherical liposomes comprising a lipid or a phospholipid wall, wherein the liposomes encloses curcumin, curcumin analogues, curcumin derivatives or any combinations thereof dissolved or dispersed in an aqueous or a non-aqueous solvent with one or more optional related co-factors, proteins, antibodies, pain medications, and other pharmaceutically active agents dissolved, dispersed or suspended in the solvent; a suitable aqueous or non-aqueous dispersion medium, wherein the one or more spherical liposomes are dispersed in the dispersion medium; and one or more optional excipients, diluents, extended or controlled release agents, lubricants, preservatives or any combinations thereof.