1 ) A process to detect drug masking adulterants in body fluids comprising the steps of: accepting the body fluid; said body fluid is divided into one or more aliquots; a first aliquot is processed via standard means; prior to processing a second aliquot a standard combination of suspected drugs at known amount(s), greater than the limit of quantitation are added to said aliquot and mixed to ensure uniformity; said second aliquot is set aside under laboratory conditions for a specified time; at the end of said specified time said second aliquots is processed via the same standard means as said first aliquot; and the results of the first aliquot, and said second aliquot are compared are compared with known test amounts of substances in artificial urine to determine if the submitted sample had added adulterants.