1. A method of matching images using a computer system, comprising: receiving, by a processor, first and second digitized images; receiving, by the processor, at least one CAD finding corresponding to a detected region of interest in the first image; and automatically determining, by the processor, at least one candidate location in the second image that matches the CAD finding in the first image based on local appearance features extracted for the CAD finding and the candidate location, wherein the automatically determining the candidate location comprises learning a distance metric and using the learned distance metric to compute, based on the local appearance features, a distance between the CAD finding in the first image and the candidate location in the second image.