1. A method for determining and responding in real-time to an increased risk of death relating to a patient with epilepsy, comprising: receiving cardiac data into a medical device; determining, using the medical device, at least one cardiac index, said at least one cardiac index being based upon the cardiac data; determining, using the medical device, an increased risk of death associated with epilepsy if the at least one cardiac index is an extreme value; issuing automatically a warning of the occurrence of the increased risk of death; and logging automatically information related to the increased risk of death, further comprising determining a further increase in the risk of death; wherein logging comprises logging at least one of a time when the increased risk of death is identified, a time when the further increased risk of death is identified, a time when the warning is issued, a type of warning issued, a body organ index related to the determined at least one index and associated with at least one of the increased risk of death or the further increased risk of death, a classification of at least one of the increased risk of death or the further increased risk of death, one or more environmental factors, one or more patient conditions, one or more patient activity factors, or one or more patient circumstances associated with the increased risk of death; and wherein the one or more environmental factors, the one or more patient activity factors, the one or more patient conditions, and the one or more patient circumstances are based upon at least one of a level of consciousness of the patient, a level, type and duration of the activity of the patient, a body posture of the patient, a time of day, a type of seizure activity, a site of origin of the seizure activity, a frequency of seizure activity, an intensity, a duration of seizure activity, an extent of spread of seizure activity, one or more brain regions engaged in seizure activity involved by severity of seizure activity, or a time spent in seizure, a seizure burden on the patient, a seizure density, the age of the patient, the physical fitness/integrity of the patient, an impact of seizure activity on the patient, or types of medications the patient takes.