1. A computer-implemented method for searching a content collection, comprising: under control of one or more computer systems configured with executable instructions, receiving a search request specifying query content to be matched with content in the content collection, the content collection characterized by a set of content descriptors; determining a set of query descriptors for the query content, the query content including one or more regions, the one or more regions including a plurality of sub-regions, at least one of the set of query descriptors associated with query descriptor components corresponding to at least partially overlapping sub-regions of one of the one or more regions that includes an identified feature of the query content; identifying a subset of the set of content descriptors that corresponds to at least a portion of the set of query descriptors; and providing for presentation at least reference to a subset of the content collection selected based at least in part on the subset of the set of content descriptors.