1. A method, comprising: identifying a sample area of a sample holder, the sample area including a biological sample; receiving image data indicative of a first portion of the sample area, the image data including first color pixel data and second color pixel data for each of a plurality of pixels; transforming the image data to generate transformed pixel data for each of the plurality of pixels which is in a different format than said image data, and which transformed pixel data includes information indicative of both a value of the first color pixel data and a value of the second color pixel data for the associated pixel.