1. A computer program product for performing a frame management function defined for a computer system of a machine architecture, the computer program product comprising: a storage medium readable by said computer system, said computer readable medium storing instructions for performing: obtaining a machine instruction containing an opcode for a set storage key and clear instruction; and executing the machine instruction comprising: obtaining a frame management field with a key field comprising a plurality of access-protection bits and a block size indicator field; obtaining an operand address of a storage frame upon which said machine instruction is to be performed, said operand address being one of an address to a large block of data and address to a small block of data; in response to a set storage key function being enabled, setting storage access-protection bits of each storage key associated with said determined block of data to a value of said access-protection bits of said key field; and in response to a clear function being enabled, clearing each block of data addressed by said operand address by setting all bytes of each block of data to zero.