1. A manufacture method of a light guide plate, comprising the following steps: providing a substrate, which comprises a first surface; forming accommodation parts, which are arranged in an array on the first surface, wherein the accommodation parts are each a circular cavity having a circular arc cross section; filling quantum dots in each of the accommodation parts; and covering the first surface of the substrate with an isolation layer such that the accommodation parts and the quantum dots filled in the accommodation parts are covered by the isolation layer, wherein the step of providing a substrate comprises: providing a substrate formation device, which receives and processes a substrate material in a molten state to form the substrate, wherein the substrate formation device comprises a first press roller and a second press roller, and a first predetermined gap is set between the first press roller and the second press roller, and the first press roller is formed of a rigid material, and the second press roller is formed of an elastic material, wherein the substrate material of the molten state passes through the first predetermined gap between the first press roller and the second press roller, and cools down to form the substrate; wherein the step of forming the accommodation parts comprises: providing a third press roller and a fourth press roller, wherein a surface of the third press roller is a smooth surface, and a surface of the fourth press roller is provided with bulges, and the third press roller is set at a first temperature, and the fourth press roller is set at a second temperature, and the first temperature is smaller than the second temperature and also smaller than a melt point of the substrate material, and a second predetermined gap is set between the third press roller and the fourth press roller; and the substrate passing through the second predetermined gap between the third press roller and the fourth press roller, such that a surface of the substrate that is close to the fourth press roller is formed with the accommodation parts, and the surface where the accommodation parts are formed is defined as the first surface; and wherein the step of filling quantum dots in each of the accommodation parts comprises: providing a fifth press roller, wherein the fifth press roller comprises a recess, in which the quantum dots are loaded, such that when the fifth press roller rolls on the first surface, the quantum dots in the recess falls into the accommodation parts to fill the quantum dots in the accommodation parts.