1. A method for computer aided detection, the method comprising: determining a pixel threshold value for an analysis of an image selected by a user, wherein the image includes a plurality of pixels; determining a segmentation setting for the analysis, the segmentation setting specifying a size of a portion of the image to be used during the analysis; analyzing, using a computer, the image by determining a difference between a first segment of the image and a second segment of the image and comparing the difference to the pixel threshold value and the segmentation setting; and identifying, using a computer, potential abnormalities in the image based on the analysis.