1. A computer-implemented method of anatomical modeling, the method comprising: determining, using a processor, a first anatomic model of one or more blood vessels of a patient; determining a biomechanical model of the one or more blood vessels using at least the first anatomic model; determining one or more parameters associated with a changed physiological state of the patient; and determining a second anatomic model incorporating geometric changes to the first anatomic model in response to the changed physiological state, using the biomechanical model and the one or more parameters associated with the changed physiological state.