1. A method of process monitoring, comprising: generating a multivariate analysis reference model of a process environment from data corresponding to monitored parameters of the process environment; identifying at least one, but less than all, of the monitored parameters having an expected maturation path that correlates to an expected maturation path of the process environment; collecting current process data corresponding to the monitored parameters, including the at least one identified parameter; and mathematically manipulating the multivariate reference model based on the current process data limited to the at least one identified parameter to account for the expected maturation path of the process environment.