1. A method of determining an estimated neural response in a hybrid electric acoustic audio prosthesis comprising: recording a B response by target nerve tissue to an electric stimulus sequence which includes: i. delivering to the target nerve tissue a first electric stimulus pulse P 1 to elicit a corresponding action potential followed by a relative refractory period, and ii. within the relative refractory period, delivering to the target nerve tissue a second electric stimulus pulse P 2 ; recording an A response by the target nerve tissue to a hybrid electric acoustic stimulus sequence which includes: i. delivering to the target nerve tissue a first reference electric stimulus pulse P 7 corresponding to the first electric stimulus pulse P 2 , and ii. delivering to the target nerve tissue an associated acoustic stimulation signal; recording a C response by the target nerve tissue to delivery of a second reference electric stimulus pulse P 5 corresponding to the first electric stimulus pulse P 1 ; processing the recorded responses to determine an artifact canceled estimated neural response Y following the relation Y=A−(B−C).