title: Calculating the average of multiple time-series with random sampling interval
body: <p>I've tried searching for answers, but couldn't find one that exactly match my problem.</p>
  
  <p>I'm doing a stochastic simulator of biological systems, where the outcome is a "Scatter-plot" time series with concentration levels at some random points in time. Now i would like to be able to take the average time-series of multiple simulation runs and are in doubt how to proceed as up to 500 simulation runs, each with several thousands measurements, can be expected.</p>
  
  <p>Naturally, i could "bucket" the intervals probably losing some precision or try to interpolate the missing measurements. But what is the preferred method in my case?</p>
  
  <p>This has to be implemented in Java and i would prefer a citation to a paper that explains the method.</p>
  
  <p>Thanks!</p>