title: Running script without virtualenv activation
body: <p>Is there a difference between running script using virtualenv interpreter (without virtualenv activation) and running it in activated virtualenv?</p>
  
  <pre><code>venv/bin/python some_script.py
  </code></pre>
  
  <p>vs</p>
  
  <pre><code>source venv/bin/activate
  python some_script.py
  </code></pre>