title: Subset of columns and filter Pandas
body: <p>Using Pandas how would I filter rows and take just a subset of columns from a pandas dataframe please in one command.</p>
  
  <p>I am trying to apply something like this....</p>
  
  <pre><code>frame[(frame.DESIGN_VALUE &gt; 20) &amp; (frame['mycol3','mycol6']))]
  </code></pre>
  
  <p>Thanks.</p>