title: Change color fill and shape of points in ggplot
body: <p>I want to change shape and color fill of points in ggplot, this is my code that worked partially, color legend is still black.</p>
  
  <pre><code>ID&lt;-rep(c("KO", "WT"), each=4)
  O&lt;-rep(c("HP", "NN"), each=2, times=2)
  Methionine&lt;-rep(c("- Methionine", "+ Methionine"), each=2, times=2)
  mean.1&lt;-sample(50:100, 8)
  se.1&lt;-runif(8, min=1, max=3)
  mydata&lt;-data.frame(ID, O, Methionine, mean.1, se.1)
  
  ggplot(mydata, aes(x=O, y=mean.1, ymax=max(mean.1), shape=Methionine, fill=ID)) + 
    geom_errorbar(aes(ymin=mean.1-se.1, ymax=mean.1+se.1), size=1,colour="black", width=.15) +
    geom_point( size = 10) +
    scale_shape_manual(labels=c("+ Methionine", "- Methionine"),
                       values = c(21,22))+
    scale_fill_manual(name=bquote(bold(paste(alpha, " "))), values = cols)
  </code></pre>