Can a Japanese word combine both on'yomi and kun'yomi characters?


I would like to know whether a Japanese word combining at least two kanji can
combine both on'yomi and kun'yomi characters, within the same word.




The answer is yes. There are "重箱読み (ju-bako-yomi)" and "湯桶読み (yu-tou-yomi)" in
Japanese vocabulary (in 2 kanji words only).

重箱 is read as Ju-bako. "Ju" is on'yomi and "bako" is kun'yomi. Like this, it
is called 重箱読み when 1st kanji is on'yomi and 2nd kanji is kun'yomi.

湯桶 is read as Yu-tou. "Yu" is kun'yomi and "tou" is on'yomi. Like this, it is
called 湯桶読み when 1st kanji is kun'yomi and 2nd kanji is on'yomi.

Other examples:

> 王様(ou-sama) : on + kun --> 重箱読み  
>  味方(mi-kata) : on + kun --> 重箱読み  
>  丸太(maru-ta) : kun + on --> 湯桶読み  
>  見本(mi-hon ) : kun + on --> 湯桶読み

