What does ～ながらにして mean?


Can someone please explain the bold grammar?

> せんてんてき 【先天的】 《ダナ》生まれ **ながらにして** 持っていること




I suppose "生まれながらにして" almost always comes together, people rarely use only
"~ながらにして" with othre nouns or conjugated verb from as long as my conscious
life.
<https://thesaurus.weblio.jp/content/%E3%81%86%E3%81%BE%E3%82%8C%E3%81%AA%E3%81%8C%E3%82%89%E3%81%AB%E3%81%97%E3%81%A6>
As the website above, "生まれながらにして" has more idiomatic sense as a whole.

It's an intriguing phrase, off the top of my head, "~ながら" itself is frequently
used as a way of conveying the meaning 'doing something while doing something
else', check out this <http://www.e-japanese.jp/?p=291>

–– Additional ––

So what is the sense of "して/にして" in "~ながらにして"? Well, I got the impression that
it's almost the same meaning of 'even though/despite' in English.

