Kaitai Shinsyo is a Japanese first medical textbook (on European medical technology), late <a href="https://en.wikipedia.org/wiki/en:Edo_Period" class="extiw" title="w:en:Edo Period">Edo Period</a>, published on 1774.  This textbook is owned and exhibited at The Center for Regional Culture and History at Saga University.
<bdi><a href="https://en.wikipedia.org/wiki/en:Sugita_Genpaku" class="extiw" title="w:en:Sugita Genpaku"><span title="Japanese scholar">Sugita Genpaku</span></a>
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佐賀大学地域学歴史文化研究センター