(original caption) Figure 1. The 16th-century population collapse in Mexico, based on estimates of Cook and Simpson (1). The 1545 and 1576 cocoliztli epidemics appear to have been hemorrhagic fevers caused by an indigenous viral agent and aggravated by unusual climatic conditions. The Mexican population did not recover to pre-Hispanic levels until the 20th century.
Rodolfo Acuna-Soto, David W. Stahle, Malcolm K. Cleaveland, and Matthew D. Therrell
2002-04
<cite style="font-style:normal">“<a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730237">Megadrought and Megadeath in 16th Century Mexico</a>” (PDF). <i><a href="https://en.wikipedia.org/wiki/Emerging_Infectious_Diseases" class="extiw" title="w:Emerging Infectious Diseases">Emerging Infectious Diseases</a></i> <b>8</b> (4): 360–362. Atlanta, GA: <a href="https://en.wikipedia.org/wiki/en:Centers_for_Disease_Control_and_Prevention" class="extiw" title="w:en:Centers for Disease Control and Prevention">Centers for Disease Control and Prevention</a>. <a href="https://en.wikipedia.org/wiki/Digital_object_identifier" class="extiw" title="w:Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.3201/eid0804.010175">10.3201/eid0804.010175</a>. <a href="https://en.wikipedia.org/wiki/PMID" class="extiw" title="w:PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/11971767">11971767</a>. <a href="https://en.wikipedia.org/wiki/PubMed_Central" class="extiw" title="w:PubMed Central">PMC</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730237">2730237</a>. <a href="https://en.wikipedia.org/wiki/International_Standard_Serial_Number" class="extiw" title="en:International Standard Serial Number">ISSN</a> <a rel="nofollow" class="external text" href="https://www.worldcat.org/issn/1080-6059">1080-6059</a>. Retrieved on <span class="mw-formatted-date" title="2018-12-07">2018-12-07</span>.</cite>