<div class="description">
<p>Antibiotic resistance and antibiotics in endodontics<br>Lieutenant Brent. J. Crumpton, DC, USNR, Captain Scott B. McClanahan, DC, USN<br><br>Antibiotic resistance has been called one of the world's most pressing public health problems. Antibiotic resistance is not a new problem. Resistant disease strains began emerging not long after the discovery of antibiotics more than 50 years ago. Penicillin and other antibiotics, which were initially viewed as miracle drugs for their ability to cure such serious and often life-threatening diseases as bacterial meningitis, typhoid fever, and rheumatic fever, soon were challenged by some defiant strains. Antibiotic resistance is a major contributor to the disease, death, and costs resulting from hospital-acquired infections. One report placed the annual cost of antimicrobial resistance among a single pathogen (Staphylococcus aureus) at $122 million. Antibiotic resistance has made potential killers out of bacteria that previously posed little threat to mankind. The indiscriminate and reckless use of antibiotics has led to a fast- approaching crisis in which human dominance of the planet is threatened by single, elementary cells of the microbial world. Reasons for the development of antimicrobial resistance fall into two broad categories: over-prescription by health-care providers and improper use by patients. Although physician over-prescription for upper respiratory infections is the single largest reason for the development of resistant microbial strains, over-prescription for dental problems and/or dental pain is emerging as a growing threat. The purpose of this clinical update is to review the Centers for Disease Control and Prevention (CDC) recommendations regarding antibiotic use and to review the literature regarding antibiotic use in endodontics.
</p>
<br>Subjects: Drug Resistance; Microbial ; Endodontics</div>
<div class="fn value">
U.S. Navy. Naval Postgraduate Dental School</div>
<dl><dd><a rel="nofollow" class="external free" href="https://archive.org/details/03012AntibioticResistanceAndAntibioticsInEndodontics">https://archive.org/details/03012AntibioticResistanceAndAntibioticsInEndodontics</a></dd>
<dd><a rel="nofollow" class="external free" href="https://archive.org/download/03012AntibioticResistanceAndAntibioticsInEndodontics/03_-_012%20Antibiotic%20resistance%20and%20antibiotics%20in%20endodontics.pdf">https://archive.org/download/03012AntibioticResistanceAndAntibioticsInEndodontics/03_-_012%20Antibiotic%20resistance%20and%20antibiotics%20in%20endodontics.pdf</a></dd></dl>