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<p>Regenerative Endodontics: Part 1<br>Lieutenant Commander Christopher E. Sandlin, DC, USN, Captain Patricia A. Tordik DC, USN<br><br>Introduction<br>The dental pulp is of mesenchymal origin. It is a complex tissue comprised of nerves, connective tissue fibers, odontoblasts, fibroblasts, immunocompetent cells, stem cells, vascular tissue, ground substance, interstitial fluid, and other cellular components. The close relationship between odontoblasts and dentin is often referred to as the dentin-pulp complex. The function of pulp as sensory tissue is well known. However, pulp tissue also has regenerative potential equally important in its protective role. It has a lifelong ability to produce new dentin in response to trauma and disease. Once the functional properties of the pulp are restored, continued dentin formation is possible. A vital pulp also protects against apical periodontitis.<br><br>Preservation of the natural dentition remains a primary objective in endodontic practice. When the pulp is diseased or necessitates removal for restorative reasons, it can be replaced with an artificial filling material. Esthetics, form and function are not primarily dependent upon a vital pulp after root maturation, but there are disadvantages to conventional root canal treatment.
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<br>Subjects: Root Canal Therapy; Dental Pulp Cavity; Dentin; Dentition; Endodontics</div>
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U.S. Navy. Naval Postgraduate Dental School</div>
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