<p>Ribbon diagram of the <a href="https://en.wikipedia.org/wiki/fragment_antigen_binding" class="extiw" title="w:fragment antigen binding">Fab fragment</a> of <a href="https://en.wikipedia.org/wiki/alemtuzumab" class="extiw" title="w:alemtuzumab">alemtuzumab</a>, a <a href="https://en.wikipedia.org/wiki/monoclonal_antibody" class="extiw" title="w:monoclonal antibody">monoclonal antibody</a>, bound to a small synthetic <a href="https://en.wikipedia.org/wiki/antigen" class="extiw" title="w:antigen">antigen</a>. Created using <a rel="nofollow" class="external text" href="http://www.accelrys.com/products/downloads/ds_visualizer/index.html">Accelrys DS Visualizer Pro 1.6</a> and <a href="https://en.wikipedia.org/wiki/GIMP" class="extiw" title="w:GIMP">GIMP</a>.
</p>
<dl><dt>Legend</dt></dl><div class="legend" style="direction:ltr;line-height:23px;"><div class="legend-content" style="display:inline-block;vertical-align:top;box-sizing:border-box;width:34px;height:23px;overflow:hidden;font-size:15px;border:thin solid #333;background:#00AAFF;color:#202122;text-align:center;"> </div> <a href="https://en.wikipedia.org/wiki/Heavy_chain" class="extiw" title="w:Heavy chain">Heavy chain</a></div>
<div class="legend" style="direction:ltr;line-height:23px;"><div class="legend-content" style="display:inline-block;vertical-align:top;box-sizing:border-box;width:34px;height:23px;overflow:hidden;font-size:15px;border:thin solid #333;background:#CDEFFF;color:#202122;text-align:center;"> </div> <a href="https://en.wikipedia.org/wiki/Light_chain" class="extiw" title="w:Light chain">Light chain</a></div>
<div class="legend" style="direction:ltr;line-height:23px;"><div class="legend-content" style="display:inline-block;vertical-align:top;box-sizing:border-box;width:34px;height:23px;overflow:hidden;font-size:15px;border:thin solid #333;background:#FFAA00;color:#202122;text-align:center;"> </div> <a href="https://en.wikipedia.org/wiki/Antigen" class="extiw" title="w:Antigen">Antigen</a></div>
<a href="//commons.wikimedia.org/wiki/User:Fvasconcellos" title="User:Fvasconcellos">Fvasconcellos</a> 02:03, 28 May 2007 (UTC)
From <a href="https://en.wikipedia.org/wiki/Protein_Data_Bank" class="extiw" title="w:Protein Data Bank">PDB</a> entry <a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CE1">1CE1</a>.<br>More information: <cite style="font-style:normal">James LC, Hale G, Waldmann H, Bloomer AC, Waldman H (1999). "1.9 Å structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen". <i>J Mol Biol</i> <b>289</b> (2): 293–301. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/10366506?dopt=Abstract">PMID 10366506</a>.</cite> <a href="https://en.wikipedia.org/wiki/Digital_object_identifier" class="extiw" title="w:Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1006%2Fjmbi.1999.2750">10.1006/jmbi.1999.2750</a>.