Mahmut Pasha Hamam, probably part of the Mahmut Pasha külliye (complex) which included the nearby Mahmut Pasha Mosque. This is one of the oldest Ottoman hamams in the city but is now used as a shopping or boutique center.
According to Dogan Kuban ("Ottoman Architecture", 2010) it is dated to 1466, though another guidebook to the city ("Strolling Through Istanbul", 2010 edition) it is dated to 1476. (One of those might be a typo of the other.)
<a href="//commons.wikimedia.org/wiki/User:R_Prazeres" title="User:R Prazeres">R Prazeres</a>
CC BY-SA 4.0
<span class="int-own-work" lang="en">Own work</span>