Population structure of centenarians and controls. Scatter plot of principal components 1 and 2 (PC1 and 2 PC2, top panels), and principal components 3 and 4 (PC3 and PC4, bottom panels) in subjects from the New England Centenarian Study, NECS (left) and Illumina control database (right) that were estimated using genome wide data. We labeled the clusters by ethnicity using the information about mother tongue and place of birth of NECS subjects and their parents. Note that some of the European ethnic groups in controls (NECS and Illumina) are not represented in NECS cases, for example Italics (⊗ green), Saxon/Scandinavia (× green), Celtics/Alpine (■, red), and Franks (○, red).
Paola Sebastiani , Nadia Solovieff, Andrew T. DeWan, Kyle M. Walsh, Annibale Puca, Stephen W. Hartley, Efthymia Melista, Stacy Andersen, Daniel A. Dworkis, Jemma B. Wilk, Richard H. Myers, Martin H. Steinberg, Monty Montano, Clinton T. Baldwin, Josephine Hoh, Thomas T. Perls
CC BY 2.5
Sebastiani P, Solovieff N, DeWan AT, Walsh KM, Puca A, Hartley SW, et al. (2012) Genetic Signatures of Exceptional Longevity in Humans. PLoS ONE 7(1): e29848. doi:10.1371/journal.pone.0029848 <a rel="nofollow" class="external free" href="http://journals.plos.org/plosone/article?id=info:doi/10.1371/journal.pone.0029848">http://journals.plos.org/plosone/article?id=info:doi/10.1371/journal.pone.0029848</a>