PLK1 is required for efficient formation of the acentriolar spindle. Time-lapse imaging of meiosis I in oocytes expressing EGFP-MAP4 (microtubules, green) and H2B-mCherry (chromosomes, red) in the presence of DMSO (control, left) or 100 nM BI2536 (right). Maximum intensity z-projection images are shown. Time after NEBD (hh:mm:ss). Scale bar = 10 μm.
Solc P, Kitajima T, Yoshida S, Brzakova A, Kaido M, Baran V, Mayer A, Samalova P, Motlik J, Ellenberg J
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<a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319955/bin/pone.0116783.s010.mp4">S3 Movie</a> from <cite style="font-style:normal">Solc P, Kitajima T, Yoshida S, Brzakova A, Kaido M, Baran V, Mayer A, Samalova P, Motlik J, Ellenberg J (2015). "<a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319955">Multiple Requirements of PLK1 during Mouse Oocyte Maturation</a>". <i>PLOS ONE</i>. <a href="https://en.wikipedia.org/wiki/Digital_object_identifier" class="extiw" title="w:Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1371/journal.pone.0116783">10.1371/journal.pone.0116783</a>. <a href="https://en.wikipedia.org/wiki/PMID" class="extiw" title="w:PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/25658810">25658810</a>. <a href="https://en.wikipedia.org/wiki/PubMed_Central" class="extiw" title="w:PubMed Central">PMC</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319955">4319955</a>.</cite>