Palladin Expression in Primary Cultures of Pancreatic Ductal Cells Derived from Increasingly Neoplastic Samples. Expression of Palladin RNA increases relative to the degree of precancer to cancer: normal to PanIN 1 (hyperplasia) to PanIN 3 (carcinoma in situ) to cancer. Each bar represents epithelial cell cultures from one person. The PanIN 1 and PanIN 3 lesions (lower left photomicrograph) were purified from two affected members of Family X. The pancreatic cancer epithelial cells (lower right photomicrograph) were purified from a sample of sporadic adenocarcinoma.
<ul><li>original work (<a href="//commons.wikimedia.org/wiki/File:Palladin_expression_neoplasia.png" title="File:Palladin expression neoplasia.png">Palladin_expression_neoplasia.png</a>) by <a href="//commons.wikimedia.org/wiki/User:Filip_em" title="User:Filip em">Filip_em</a>, based on: Pogue-Geile KL, Chen R, Bronner MP, Crnogorac-Jurcevic T, Moyes KW, et al. (2006) Palladin Mutation Causes Familial Pancreatic Cancer and Suggests a New Cancer Mechanism. PLoS Med 3(12): e516. doi:10.1371/journal.pmed.0030516. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/17194196?dopt=Abstract">PMID 17194196</a></li>
<li>original derivative work (<a href="//commons.wikimedia.org/wiki/File:Pancreas_neoplasia_carcinoma_sequence.png" title="File:Pancreas neoplasia carcinoma sequence.png">Pancreas neoplasia carcinoma sequence.png</a>) by <a href="//commons.wikimedia.org/wiki/User:Nephron" title="User:Nephron">Nephron</a></li>
<li>derivative work: <a href="//commons.wikimedia.org/wiki/User:M1llx" title="User:M1llx">M1llx</a> (<a href="https://pl.wikipedia.org/wiki/Dyskusja_wikipedysty:M1llx" class="extiw" title="pl:Dyskusja wikipedysty:M1llx">zgłoś błąd</a>)</li></ul>
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