Figure 1. Schematic representation of the three main dose–response models linking cancer risk to dose of IR exposure. The Linear Non-Threshold (LNT) model states that cancer risk increases with dose in a linear fashion from a dose of zero units onwards. It is supported by human epidemiological data at intermediate to high doses, whereas supporting evidence in the low dose region (&lt;100 mGy) is weak. The LNT is a foundation of the regulatory policies put forth by the International Commission on Radiological Protection. The Threshold model implies the existence of a threshold dose, below which no measurable increase in cancer risk is observed. The radiation hormesis model assumes a negative cancer risk at low-dose exposures, resulting in protection from cancer. The radiation hormesis model is supported by a large body of radiobiological literature showing beneficial responses to LDR, including in vivo animal cancer and mortality studies.
Kabilan, U.; Graber, T.E.; Alain, T.; Klokov, D.
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<p>Kabilan, U.; Graber, T.E.; Alain, T.; Klokov, D. Ionizing Radiation and Translation Control: A Link to Radiation Hormesis? Int. J. Mol. Sci. 2020, 21, 6650. 
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