Complex nodal line dynamics in LQT1 TICM. Top panels: Vm and Ca2+. Bottom panels: Vm and Ca2+ nodal lines. The nodal lines of LQT1-TICM demonstrated complex patterns including genesis, vanishing, wiggling, and moving. The spatiotemporal patterns of nodal lines of action potential and Ca2+ transient were also complex. This movie corresponds to Fig 7A in the manuscript.
Lau E, Kossidas K, Kim T, Kunitomo Y, Ziv O, Zhen S, Taylor C, Schofield L, Yammine J, Liu G, Peng X, Qu Z, Koren G, Choi B
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<a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430457/bin/pone.0122754.s006.mp4">S1 Movie</a> from <cite style="font-style:normal">Lau E, Kossidas K, Kim T, Kunitomo Y, Ziv O, Zhen S, Taylor C, Schofield L, Yammine J, Liu G, Peng X, Qu Z, Koren G, Choi B (2015). "<a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430457">Spatially Discordant Alternans and Arrhythmias in Tachypacing-Induced Cardiac Myopathy in Transgenic LQT1 Rabbits: The Importance of IKs and Ca2+ Cycling</a>". <i>PLOS ONE</i>. <a href="https://en.wikipedia.org/wiki/Digital_object_identifier" class="extiw" title="w:Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1371/journal.pone.0122754">10.1371/journal.pone.0122754</a>. <a href="https://en.wikipedia.org/wiki/PMID" class="extiw" title="w:PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/25970695">25970695</a>. <a href="https://en.wikipedia.org/wiki/PubMed_Central" class="extiw" title="w:PubMed Central">PMC</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430457">4430457</a>.</cite>