Tumor survives. This movie shows a representative simulation that results in tumor survival under the base parameter set. Tumor cells are shown top left (red: alive, black: dead); Macrophages are shown top middle (blue: naïve, red: M1, green: M2). The four diffusible signals (TLS, M2S, Oxygen, Activator) are shown top right and in the bottom row, respectively. Concentrations are represented by color (low = blue, medium = yellow/green, red = high).
Wells D, Chuang Y, Knapp L, Brockmann D, Kath W, Leonard J
CC BY 4.0
<a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408028/bin/pcbi.1004181.s010.mp4">S1 Movie</a> from <cite style="font-style:normal">Wells D, Chuang Y, Knapp L, Brockmann D, Kath W, Leonard J (2015). "<a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408028">Spatial and Functional Heterogeneities Shape Collective Behavior of Tumor-Immune Networks</a>". <i>PLOS Computational Biology</i>. <a href="https://en.wikipedia.org/wiki/Digital_object_identifier" class="extiw" title="w:Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1371/journal.pcbi.1004181">10.1371/journal.pcbi.1004181</a>. <a href="https://en.wikipedia.org/wiki/PMID" class="extiw" title="w:PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/25905470">25905470</a>. <a href="https://en.wikipedia.org/wiki/PubMed_Central" class="extiw" title="w:PubMed Central">PMC</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408028">4408028</a>.</cite>