Preclinical applications of fUS imaging. Setups for awake rats (a) or mice (b). (c) Ultra high-sensitivity Doppler allows whole-brain imaging in rats [14]. (d) Hyperemia induced by whiskers stimulation in the barrel cortex and in the ventral posterior medial nucleus. (e) Propagation of an epileptiform seizure in the rat brain. (f) 3D reconstruction of the activated visual system of an anesthetized rat. (g) Resting state connectivity matrix in an anesthetized rat. The anti-diagonal represents the interhemispheric functional coupling. Lower panel: different protocols and animal models tested.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1">[1]</a></sup>
Thomas Deffieux, Charlie Demene, Mathieu Pernot, Mickael Tanter
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