A paraffin section of E15.5 wildtype mouse testis fluorescently stained with antibodies detecting the Sertoli cell marker SOX9 (green) and the Leydig cell marker 3beta-HSD (red). Nuclei (blue) are stained with DAPI. Sertoli cells are found within the tubular-like testes cords and play multiple roles in testes cell differentiation and morphogenesis. On the other hand, Leydig cells populate the interstitial compartment and mediate male steroidogenesis.Hudson Institute of Medical Research, Melbourne, Australia.
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